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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:rodenticide
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Accession:CHEBI:33288 term browser browse the term
Definition:A substance used to destroy rodent pests.
Synonyms:related_synonym: rodenticides
 xref: Wikipedia:Rodenticide



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gamma-hexachlorocyclohexane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase decreases activity EXP Hexachlorocyclohexane results in decreased activity of CAT protein CTD PMID:16838206 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
sodium arsenite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 increases degradation
multiple interactions
decreases expression
EXP sodium arsenite results in increased degradation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of AKT1 protein]; sodium arsenite results in decreased expression of and results in increased phosphorylation of AKT1 protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]
sodium arsenite results in decreased expression of AKT1 protein
CTD PMID:12760830 PMID:16239170
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
EXP bisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]; Go 6976 inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]
sodium arsenite results in increased expression of HIF1A mRNA; sodium arsenite results in increased expression of HIF1A protein
CTD PMID:15089098 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G MAPK6 mitogen-activated protein kinase 6 increases expression EXP sodium arsenite results in increased expression of MAPK6 protein CTD PMID:12760830 NCBI chr 1:119,725,026...119,770,988
Ensembl chr 1:119,725,029...119,771,312
JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
increases degradation
decreases expression
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of NOS3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of NOS3 protein]; sodium arsenite results in increased phosphorylation of and results in decreased activity of NOS3 protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of NOS3 protein]
sodium arsenite results in decreased expression of NOS3 protein
CTD PMID:16239170 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha decreases expression EXP sodium arsenite results in decreased expression of PRKACA protein CTD PMID:12760830 NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,553
JBrowse link
G PRKCD protein kinase C delta increases phosphorylation EXP sodium arsenite results in increased phosphorylation of PRKCD protein CTD PMID:15089098 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,264...35,323,356
JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 decreases expression EXP sodium arsenite results in decreased expression of RPS6KA1 protein CTD PMID:12760830 NCBI chr 6:83,905,124...83,947,189
Ensembl chr 6:83,905,076...83,950,984
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
increases activity
EXP [sodium arsenite results in increased activity of SOD1 protein] which results in increased abundance of Hydrogen Peroxide CTD PMID:12530527 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,749
JBrowse link
G TP53 tumor protein p53 increases expression EXP sodium arsenite results in increased expression of TP53 CTD PMID:13129816 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
G VEGFA vascular endothelial growth factor A increases expression
multiple interactions
EXP sodium arsenite results in increased expression of VEGFA mRNA
bisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; R 59949 promotes the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; sodium arsenite results in increased expression of and results in increased secretion of VEGFA protein
CTD PMID:15089098 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
strychnine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM2 cholinergic receptor muscarinic 2 multiple interactions EXP Strychnine analog promotes the reaction [N-Methylscopolamine binds to CHRM2 protein] CTD PMID:12757728 NCBI chr18:12,455,139...12,600,314
Ensembl chr18:12,455,150...12,600,249
JBrowse link
warfarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 multiple interactions EXP [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 protein; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA] CTD PMID:29358327 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,215
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of CDKN1A protein CTD PMID:29358327 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
JBrowse link
G EP300 E1A binding protein p300 multiple interactions EXP [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of EP300 protein CTD PMID:29358327 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions EXP [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein] CTD PMID:29358327 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,513...40,459,686
JBrowse link
G SNAI2 snail family transcriptional repressor 2 multiple interactions EXP [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of SNAI2 protein; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein]; SNAI2 protein promotes the reaction [TP53 protein results in increased susceptibility to Warfarin]; Warfarin promotes the reaction [TP53 protein binds to SNAI2 promoter] CTD PMID:29358327 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,878...79,268,475
JBrowse link
G TP53 tumor protein p53 increases response to substance
increases expression
multiple interactions
EXP TP53 protein results in increased susceptibility to Warfarin
Warfarin results in increased expression of TP53 mRNA
[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of CDKN1A protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of EP300 protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein; [TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of SNAI2 protein; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of BMP2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 mRNA]; SNAI2 protein promotes the reaction [[TP53 protein results in increased susceptibility to Warfarin] which results in increased expression of RUNX2 protein]; SNAI2 protein promotes the reaction [TP53 protein results in increased susceptibility to Warfarin]; Warfarin promotes the reaction [TP53 protein binds to SNAI2 promoter]; Warfarin results in increased expression of and results in decreased acetylation of TP53 protein
CTD PMID:29358327 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link

Term paths to the root
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  CHEBI ontology 1029
    role 969
      application 804
        pesticide 146
          rodenticide 17
            endrin 0
            ethanethiol 0
            gamma-hexachlorocyclohexane 1
            lead arsenate 0
            scilliroside 0
            sodium arsenite 10
            sodium fluoroacetate 0
            strychnine + 1
            strychnine hydrochloride 0
            thallium sulfate 0
            undecan-2-one 0
            vitamin D2 + 0
            warfarin 6
            warfarin potassium 0
            warfarin sodium 0
paths to the root