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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:beta-tocotrienol
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Accession:CHEBI:33275 term browser browse the term
Definition:A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5 and 8 and a farnesyl chain at position 2. It has been isolated from various cultivars of wheat.
Synonyms:exact_synonym: (2R)-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-chromen-6-ol
 related_synonym: (2R)-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-1-benzopyran-6-ol;   (2R)-3,4-dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol;   Formula=C28H42O2;   InChI=1S/C28H42O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-24(6)26(29)19-23(5)27(25)30-28/h11,13,15,19,29H,8-10,12,14,16-18H2,1-7H3/b21-13+,22-15+/t28-/m1/s1;   InChIKey=FGYKUFVNYVMTAM-WAZJVIJMSA-N;   SMILES=CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC[C@]1(C)CCc2c(C)c(O)cc(C)c2O1;   epsilon-tocopherol
 alt_id: CHEBI:35070
 xref: AGR:IND44045372;   AGR:IND607266641;   Beilstein:43513;   CAS:490-23-3;   Chemspider:4445513;   FooDB:FDB002433;   HMDB:HMDB0030554;   KEGG:C14154;   KNApSAcK:C00035060;   LIPID_MAPS_instance:LMPR02020055
 xref_mesh: MESH:C082089
 xref: MetaCyc:CPD-15837;   PMID:11902929;   PMID:14747214;   PMID:18921970;   PMID:20413888;   PMID:32283796;   Patent:CN101842488;   Patent:EP1948808;   Patent:EP2198029;   Patent:MX2010003631;   Patent:US2007021497;   Patent:US2011113503;   Reaxys:43513;   Wikipedia:Beta-Tocotrienol


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beta-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO tocotrienol, beta results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO tocotrienol, beta results in increased expression of CYP3A4 CTD PMID:15269186 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO tocotrienol, beta binds to and results in increased activity of NR1I2 protein; tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO tocotrienol, beta results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      chemical role 19421
        antioxidant 15726
          vitamin E 1739
            beta-tocotrienol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic molecule 19656
                              organic cyclic compound 19461
                                organic heterocyclic compound 18817
                                  oxacycle 17770
                                    benzopyran 11699
                                      1-benzopyran 11461
                                        chromanes 3943
                                          chromanol 1739
                                            chroman-6-ol 1739
                                              tocol 257
                                                tocotrienol 43
                                                  beta-tocotrienol 5
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