|
G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Hydrogen co-treated with APP protein] results in increased expression of CAT protein; [Hydrogen co-treated with APP protein] results in increased expression of SOD1 protein; dorsomorphin inhibits the reaction [Hydrogen inhibits the reaction [APP protein results in decreased expression of FOXO3 protein]]; dorsomorphin inhibits the reaction [Hydrogen inhibits the reaction [APP protein results in decreased expression of SIRT1 protein]]; Hydrogen inhibits the reaction [APP protein results in decreased expression of and affects the localization of FOXO3 protein]; Hydrogen inhibits the reaction [APP protein results in decreased expression of CAT mRNA]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SIRT1 protein]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD1 mRNA]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD1 protein]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD2 mRNA]; Hydrogen inhibits the reaction [APP protein results in increased cleavage of CASP3 protein]; Hydrogen inhibits the reaction [APP protein results in increased cleavage of PARP1 protein] |
CTD |
PMID:26271894 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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|
G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [APP protein results in increased cleavage of CASP3 protein] |
CTD |
PMID:26271894 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
|
|
G |
Cat |
catalase |
multiple interactions increases expression |
ISO |
[Hydrogen co-treated with APP protein] results in increased expression of CAT protein; Hydrogen inhibits the reaction [APP protein results in decreased expression of CAT mRNA] Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of CAT mRNA] Hydrogen results in increased expression of CAT mRNA; Hydrogen results in increased expression of CAT protein |
CTD |
PMID:26271894 PMID:32955216 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
|
|
G |
Foxo3 |
forkhead box O3 |
multiple interactions increases expression |
ISO |
dorsomorphin inhibits the reaction [Hydrogen inhibits the reaction [APP protein results in decreased expression of FOXO3 protein]]; Hydrogen inhibits the reaction [APP protein results in decreased expression of and affects the localization of FOXO3 protein] Hydrogen results in increased expression of FOXO3 protein |
CTD |
PMID:26271894 |
|
NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLC mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLM mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
|
|
G |
Gfap |
glial fibrillary acidic protein |
multiple interactions |
EXP |
Hydrogen inhibits the reaction [[Chlorpyrifos co-treated with Lipopolysaccharides] results in increased expression of GFAP protein] |
CTD |
PMID:30236991 |
|
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GPX1 mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
|
|
G |
Ldha |
lactate dehydrogenase A |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of LDHA mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
|
|
G |
Nox4 |
NADPH oxidase 4 |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of NOX4 mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [APP protein results in increased cleavage of PARP1 protein] |
CTD |
PMID:26271894 |
|
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Hydrogen inhibits the reaction [[Chlorpyrifos co-treated with Lipopolysaccharides] results in increased phosphorylation of RELA protein] |
CTD |
PMID:30236991 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
|
|
G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in increased expression of SCD1 mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
|
|
G |
Sirt1 |
sirtuin 1 |
increases expression multiple interactions |
ISO |
Hydrogen results in increased expression of SIRT1 protein dorsomorphin inhibits the reaction [Hydrogen inhibits the reaction [APP protein results in decreased expression of SIRT1 protein]]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SIRT1 protein] |
CTD |
PMID:26271894 |
|
NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
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|
G |
Sod1 |
superoxide dismutase 1 |
multiple interactions increases expression |
ISO |
[Hydrogen co-treated with APP protein] results in increased expression of SOD1 protein; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD1 mRNA]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD1 protein] Hydrogen results in increased expression of SOD1 mRNA; Hydrogen results in increased expression of SOD1 protein |
CTD |
PMID:26271894 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
|
|
G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions |
ISO |
Hydrogen results in increased expression of SOD2 protein Hydrogen inhibits the reaction [Chlorpyrifos results in increased expression of SOD2 mRNA] Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD2 mRNA] |
CTD |
PMID:26271894 PMID:32955216 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
|
|
G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
EXP |
Hydrogen inhibits the reaction [Chlorpyrifos promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]] |
CTD |
PMID:30236991 |
|
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
|
|
|
G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Hydrogen co-treated with APP protein] results in increased expression of CAT protein; [Hydrogen co-treated with APP protein] results in increased expression of SOD1 protein; dorsomorphin inhibits the reaction [Hydrogen inhibits the reaction [APP protein results in decreased expression of FOXO3 protein]]; dorsomorphin inhibits the reaction [Hydrogen inhibits the reaction [APP protein results in decreased expression of SIRT1 protein]]; Hydrogen inhibits the reaction [APP protein results in decreased expression of and affects the localization of FOXO3 protein]; Hydrogen inhibits the reaction [APP protein results in decreased expression of CAT mRNA]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SIRT1 protein]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD1 mRNA]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD1 protein]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD2 mRNA]; Hydrogen inhibits the reaction [APP protein results in increased cleavage of CASP3 protein]; Hydrogen inhibits the reaction [APP protein results in increased cleavage of PARP1 protein] |
CTD |
PMID:26271894 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
|
|
G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [APP protein results in increased cleavage of CASP3 protein] |
CTD |
PMID:26271894 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
|
|
G |
Cat |
catalase |
multiple interactions increases expression |
ISO |
[Hydrogen co-treated with APP protein] results in increased expression of CAT protein; Hydrogen inhibits the reaction [APP protein results in decreased expression of CAT mRNA] Hydrogen results in increased expression of CAT mRNA; Hydrogen results in increased expression of CAT protein Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of CAT mRNA] |
CTD |
PMID:26271894 PMID:32955216 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
|
|
G |
Foxo3 |
forkhead box O3 |
multiple interactions increases expression |
ISO |
dorsomorphin inhibits the reaction [Hydrogen inhibits the reaction [APP protein results in decreased expression of FOXO3 protein]]; Hydrogen inhibits the reaction [APP protein results in decreased expression of and affects the localization of FOXO3 protein] Hydrogen results in increased expression of FOXO3 protein |
CTD |
PMID:26271894 |
|
NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLC mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLM mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
|
|
G |
Gfap |
glial fibrillary acidic protein |
multiple interactions |
EXP |
Hydrogen inhibits the reaction [[Chlorpyrifos co-treated with Lipopolysaccharides] results in increased expression of GFAP protein] |
CTD |
PMID:30236991 |
|
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GPX1 mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
|
|
G |
Ldha |
lactate dehydrogenase A |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of LDHA mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
|
|
G |
Nox4 |
NADPH oxidase 4 |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of NOX4 mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [APP protein results in increased cleavage of PARP1 protein] |
CTD |
PMID:26271894 |
|
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Hydrogen inhibits the reaction [[Chlorpyrifos co-treated with Lipopolysaccharides] results in increased phosphorylation of RELA protein] |
CTD |
PMID:30236991 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
|
|
G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
Hydrogen inhibits the reaction [Chlorpyrifos results in increased expression of SCD1 mRNA] |
CTD |
PMID:32955216 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
|
|
G |
Sirt1 |
sirtuin 1 |
increases expression multiple interactions |
ISO |
Hydrogen results in increased expression of SIRT1 protein dorsomorphin inhibits the reaction [Hydrogen inhibits the reaction [APP protein results in decreased expression of SIRT1 protein]]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SIRT1 protein] |
CTD |
PMID:26271894 |
|
NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
|
|
G |
Sod1 |
superoxide dismutase 1 |
multiple interactions increases expression |
ISO |
[Hydrogen co-treated with APP protein] results in increased expression of SOD1 protein; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD1 mRNA]; Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD1 protein] Hydrogen results in increased expression of SOD1 mRNA; Hydrogen results in increased expression of SOD1 protein |
CTD |
PMID:26271894 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
|
|
G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions |
ISO |
Hydrogen results in increased expression of SOD2 protein Hydrogen inhibits the reaction [APP protein results in decreased expression of SOD2 mRNA] Hydrogen inhibits the reaction [Chlorpyrifos results in increased expression of SOD2 mRNA] |
CTD |
PMID:26271894 PMID:32955216 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
|
|
G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
EXP |
Hydrogen inhibits the reaction [Chlorpyrifos promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]] |
CTD |
PMID:30236991 |
|
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
|
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