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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(E)-cinnamyl alcohol
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Accession:CHEBI:33227 term browser browse the term
Definition:The E (trans) stereoisomer of cinnamyl alcohol.
Synonyms:exact_synonym: (2E)-3-phenylprop-2-en-1-ol
 related_synonym: (E)-3-phenyl-2-propen-1-ol;   3-Phenyl-2-propen-1-ol;   Formula=C9H10O;   InChI=1S/C9H10O/c10-8-4-7-9-5-2-1-3-6-9/h1-7,10H,8H2/b7-4+;   InChIKey=OOCCDEMITAIZTP-QPJJXVBHSA-N;   SMILES=OC\\C=C\\c1ccccc1;   Styrylcarbinol
 xref: Beilstein:741973;   CAS:104-54-1;   CAS:4407-36-7;   Gmelin:261108;   HMDB:HMDB0029698;   KEGG:C02394
 xref_mesh: MESH:C020722
 xref: MetaCyc:CINNAMYL-ALC;   PMID:20431333;   PMID:20940038;   Reaxys:741973;   Wikipedia:Cinnamyl_alcohol


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(E)-cinnamyl alcohol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO cinnamyl alcohol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO cinnamyl alcohol results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases activity ISO cinnamyl alcohol results in increased activity of AKR1C2 promoter CTD PMID:21195160 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO cinnamyl alcohol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO cinnamyl alcohol results in increased expression of ATF3 mRNA CTD PMID:23999411 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions ISO BACH1 mRNA promotes the reaction [cinnamyl alcohol results in increased expression of HMOX1 mRNA] CTD PMID:26244607 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Cat catalase increases expression ISO cinnamyl alcohol results in increased expression of CAT mRNA CTD PMID:20566472 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO cinnamyl alcohol results in increased expression of CXCL2 protein CTD PMID:23178550 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO cinnamyl alcohol results in increased expression of DNAJB4 mRNA CTD PMID:23999411 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Fech ferrochelatase increases expression ISO cinnamyl alcohol results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO cinnamyl alcohol results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO cinnamyl alcohol results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO cinnamyl alcohol results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO cinnamyl alcohol results in increased expression of GCLM mRNA CTD PMID:20566472, PMID:23999411, PMID:27965148 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO cinnamyl alcohol results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO cinnamyl alcohol results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO cinnamyl alcohol results in increased expression of HMOX1 mRNA
BACH1 mRNA promotes the reaction [cinnamyl alcohol results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA promotes the reaction [cinnamyl alcohol results in increased expression of HMOX1 mRNA]
CTD PMID:20566472, PMID:23445166, PMID:26244607 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO cinnamyl alcohol results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Il18 interleukin 18 increases expression ISO cinnamyl alcohol results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO cinnamyl alcohol results in increased expression of MAFF mRNA CTD PMID:20566472 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO cinnamyl alcohol results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO cinnamyl alcohol results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr12:16,923,989...16,934,706
Ensembl chr12:16,923,990...16,934,706
JBrowse link
G Me1 malic enzyme 1 increases expression ISO cinnamyl alcohol results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO cinnamyl alcohol results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO NFE2L2 mRNA promotes the reaction [cinnamyl alcohol results in increased expression of HMOX1 mRNA] CTD PMID:26244607 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO cinnamyl alcohol results in increased expression of NQO1 mRNA CTD PMID:20566472 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO cinnamyl alcohol results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO cinnamyl alcohol results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases activity
ISO [cinnamyl alcohol co-treated with Glucose deficiency] results in decreased activity of SLC2A1 protein
cinnamyl alcohol results in increased activity of SLC2A1 protein
CTD PMID:20955755 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO cinnamyl alcohol results in increased expression of SOD1 mRNA CTD PMID:20566472 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO cinnamyl alcohol results in increased expression of SOD2 mRNA CTD PMID:20566472 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 increases expression ISO cinnamyl alcohol results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO cinnamyl alcohol results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Txn2 thioredoxin 2 increases expression ISO cinnamyl alcohol results in increased expression of TXN2 mRNA CTD PMID:20566472 NCBI chr 7:119,144,350...119,158,173
Ensembl chr 7:119,144,351...119,158,201
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO cinnamyl alcohol results in increased expression of TXNRD1 mRNA CTD PMID:20566472, PMID:23445166 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Txnrd2 thioredoxin reductase 2 increases expression ISO cinnamyl alcohol results in increased expression of TXNRD2 mRNA CTD PMID:20566472 NCBI chr11:86,667,994...86,716,063
Ensembl chr11:86,667,997...86,716,254
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO cinnamyl alcohol results in increased expression of UGT1A6 mRNA CTD PMID:20566472 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO cinnamyl alcohol results in increased expression of VEGFA protein CTD PMID:25617811 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            eukaryotic metabolite 18908
              plant metabolite 17360
                (E)-cinnamyl alcohol 38
                  (E)-5-hydroxyconiferyl alcohol 0
                  (E)-caffeyl alcohol 0
                  3,4,5-trimethoxy cinnamyl alcohol 0
                  3,4-dimethoxycinnamyl alcohol 0
                  coniferol + 0
                  trans-p-coumaryl alcohol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              organic hydroxy compound 18634
                                alcohol 14987
                                  primary alcohol 13886
                                    cinnamyl alcohol 38
                                      (E)-cinnamyl alcohol 38
                                        (E)-5-hydroxyconiferyl alcohol 0
                                        (E)-caffeyl alcohol 0
                                        3,4,5-trimethoxy cinnamyl alcohol 0
                                        3,4-dimethoxycinnamyl alcohol 0
                                        coniferol + 0
                                        trans-p-coumaryl alcohol + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.