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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:potassium cyanide
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Accession:CHEBI:33191 term browser browse the term
Definition:A cyanide salt containing equal numbers of potassium cations and cyanide anions.
Synonyms:related_synonym: Formula=CKN;   InChI=1S/CN.K/c1-2;/q-1;+1;   InChIKey=NNFCIKHAZHQZJG-UHFFFAOYSA-N;   KCN;   Kaliumcyanid;   Kaliumzyanid;   SMILES=[C-]#N.[K+];   Zyankali;   cyanide of potassium
 xref: Beilstein:3593645;   Beilstein:4652394;   CAS:151-50-8;   Gmelin:647425
 xref_mesh: MESH:D011190
 xref: PMID:16850258;   PMID:24318282;   PMID:25850896;   PMID:27170681;   PMID:27170682;   PMID:27250664;   PMID:27666790;   PMID:27737792;   Wikipedia:Potassium_cyanide


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potassium cyanide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases response to substance
multiple interactions
EXP BCL2 protein results in decreased susceptibility to Potassium Cyanide
[[pirinixic acid results in increased expression of UCP2 protein] which results in decreased expression of BCL2 protein] which results in increased susceptibility to Potassium Cyanide; Potassium Cyanide promotes the reaction [[pirinixic acid results in increased expression of UCP2 protein] which results in increased degradation of BCL2 protein]
CTD PMID:19361538 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Cth cystathionine gamma-lyase increases activity ISO Potassium Cyanide results in increased activity of CTH protein CTD PMID:23929717 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
EXP Potassium Cyanide inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA]
Potassium Cyanide results in increased expression of EGR1 mRNA
CTD PMID:10723097 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP Potassium Cyanide results in increased expression of FOS mRNA
Potassium Cyanide inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]
CTD PMID:10723097 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Potassium Cyanide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:3030588 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mpst mercaptopyruvate sulfurtransferase decreases activity ISO Potassium Cyanide results in decreased activity of MPST protein CTD PMID:23929717 NCBI chr 7:119,626,636...119,631,317
Ensembl chr 7:119,626,637...119,631,425
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP Buthionine Sulfoximine promotes the reaction [Potassium Cyanide results in increased expression of NOS2 protein]; Ethacrynic Acid promotes the reaction [Potassium Cyanide results in increased expression of NOS2 protein]; N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Potassium Cyanide results in increased expression of NOS2 protein]; S-ethyl glutathione inhibits the reaction [Potassium Cyanide results in increased expression of NOS2 protein]; SN50 peptide inhibits the reaction [Potassium Cyanide results in increased expression of NOS2 protein]
Potassium Cyanide results in increased expression of NOS2 mRNA; Potassium Cyanide results in increased expression of NOS2 protein
CTD PMID:16933320 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Slc39a8 solute carrier family 39 member 8 multiple interactions ISO Potassium Cyanide inhibits the reaction [SLC39A8 protein results in increased uptake of Cadmium] CTD PMID:16638970 NCBI chr 2:241,028,851...241,092,584
Ensembl chr 2:241,029,693...241,092,582
JBrowse link
G Sod1 superoxide dismutase 1 increases metabolic processing ISO Potassium Cyanide results in increased metabolism of SOD1 protein CTD PMID:15096637 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Tst thiosulfate sulfurtransferase affects activity ISO Potassium Cyanide affects the activity of TST protein CTD PMID:23929717 NCBI chr 7:119,616,323...119,623,072
Ensembl chr 7:119,616,324...119,623,072
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions
increases expression
EXP [[pirinixic acid results in increased expression of UCP2 protein] which results in decreased expression of BCL2 protein] which results in increased susceptibility to Potassium Cyanide; dihydroxy-vitamin D3 inhibits the reaction [pirinixic acid promotes the reaction [Potassium Cyanide results in increased expression of UCP2 protein]]; dihydroxy-vitamin D3 inhibits the reaction [Potassium Cyanide results in increased expression of UCP2 protein]; pirinixic acid promotes the reaction [Potassium Cyanide results in increased expression of UCP2 protein]; Potassium Cyanide promotes the reaction [[pirinixic acid results in increased expression of UCP2 protein] which results in increased abundance of Hydrogen Peroxide]; Potassium Cyanide promotes the reaction [[pirinixic acid results in increased expression of UCP2 protein] which results in increased degradation of BCL2 protein] CTD PMID:18183618 PMID:19361538 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      biological role 19792
        aetiopathogenetic role 18974
          neurotoxin 17616
            potassium cyanide 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            one-carbon compound 17568
                              hydrogen cyanide 2909
                                cyanides 2909
                                  cyanide salt 18
                                    potassium cyanide 11
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