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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrrolidine
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Accession:CHEBI:33135 term browser browse the term
Definition:A cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family.
Synonyms:related_synonym: 1-azacyclopentane;   Formula=C4H9N;   InChI=1S/C4H9N/c1-2-4-5-3-1/h5H,1-4H2;   InChIKey=RWRDLPDLKQPQOW-UHFFFAOYSA-N;   SMILES=C1CCNC1;   azacyclopentane;   azolidine;   butylenimine;   perhydropyrrole;   prolamine;   tetrahydropyrrole;   tetramethylenimine
 xref: Beilstein:102395;   CAS:123-75-1;   Chemspider:29008;   FooDB:FDB007401;   Gmelin:1704;   HMDB:HMDB0031641
 xref_mesh: MESH:C032519
 xref: PDBeChem:VES;   PMID:1221030;   PMID:18838771;   PMID:20024446
 cyclic_relationship: is_conjugate_base_of CHEBI:52145



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pyrrolidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hrh3 histamine receptor H3 multiple interactions EXP
ISO
pyrrolidine binds to and results in decreased activity of HRH3 protein CTD PMID:17169555 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO [pyrrolidine analog binds to Palladium binds to Diclofenac] which results in decreased activity of PON1 protein; [pyrrolidine analog binds to Palladium binds to Mefenamic Acid] which results in decreased activity of PON1 protein; [pyrrolidine analog binds to Platinum binds to Diclofenac] which results in decreased activity of PON1 protein; [pyrrolidine analog binds to Platinum binds to Mefenamic Acid] which results in decreased activity of PON1 protein CTD PMID:29512227 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      atom 19799
        nonmetal atom 19686
          nitrogen atom 18767
            nitrogen molecular entity 18767
              organonitrogen compound 18544
                organonitrogen heterocyclic compound 17661
                  azacycloalkane 142
                    pyrrolidine 2
                      N-[(Z)-dodec-2-enoyl]pyrrolidine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  organic heteromonocyclic compound 17120
                                    saturated organic heteromonocyclic parent 9797
                                      pyrrolidine 2
                                        N-[(Z)-dodec-2-enoyl]pyrrolidine 0
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