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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:calcium dichloride
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Accession:CHEBI:3312 term browser browse the term
Definition:A calcium salt that has formula CaCl2.
Synonyms:related_synonym: CaCl2;   calcium chloride;   calcium chloride anhydrous
 xref: AGR:IND607339542;   CAS:10043-52-4;   DrugBank:DB01164;   HMDB:HMDB0303526
 xref_mesh: MESH:D002122
 xref: MolBase:1869;   PPDB:109;   foodb.food:FDB015404;   kegg.compound:C08130;   metacyc.compound:CPD0-1589;   pubmed:11057678;   pubmed:13333715;   pubmed:32018153;   pubmed:32441097;   pubmed:34618995;   pubmed:34981086;   pubmed:35159430;   pubmed:35159592;   pubmed:35200459;   pubmed:35260323;   wikipedia.en:Calcium_Chloride
 chemrof_formula: Ca.2Cl
 chemrof_inchi: InChI=1S/Ca.2ClH/h;2*1H/q+2;;/p-2
 chemrof_inchikey: UXVMQQNJUSDDNG-UHFFFAOYSA-L
 chemrof_smiles: [Ca+2].[Cl-].[Cl-]


show annotations for term's descendants           Sort by:
calcium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 increases expression EXP Calcium Chloride results in increased expression of ADAM10 mRNA; Calcium Chloride results in increased expression of ADAM10 protein CTD PMID:20621845 NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases expression EXP Calcium Chloride results in increased expression of ADAM17 mRNA; Calcium Chloride results in increased expression of ADAM17 protein CTD PMID:20621845 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Calcium Chloride results in increased expression of ALPL mRNA CTD PMID:25824407 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167 		JBrowse link
G Apoc3 apolipoprotein C3 increases expression ISO Calcium Chloride results in increased expression of APOC3 protein CTD PMID:25824407 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 increases expression ISO Calcium Chloride results in increased expression of ATP5PF protein CTD PMID:25824407 NCBI chr11:37,368,045...37,375,721
Ensembl chr11:37,368,042...37,375,466 		JBrowse link
G Bag4 BAG cochaperone 4 increases expression ISO Calcium Chloride results in increased expression of BAG4 protein CTD PMID:25824407 NCBI chr16:72,991,407...73,008,620
Ensembl chr16:72,991,362...73,013,273 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO Calcium Chloride results in increased expression of BGLAP mRNA CTD PMID:25824407 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318 		JBrowse link
G Bicd2 BICD cargo adaptor 2 increases expression ISO Calcium Chloride results in increased expression of BICD2 protein CTD PMID:25824407 NCBI chr17:15,449,011...15,511,423
Ensembl chr17:15,435,894...15,511,305 		JBrowse link
G Calm3 calmodulin 3 multiple interactions ISO Calcium Chloride inhibits the reaction [CALM3 protein binds to and results in decreased activity of UBE3B protein] CTD PMID:28003368 NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:86,717,321...86,725,960 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage 		EXP cordycepin inhibits the reaction [Calcium Chloride results in increased cleavage of CASP3 protein] CTD PMID:36731150 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions 		EXP Calcium Chloride results in increased cleavage of CASP9 protein
cordycepin inhibits the reaction [Calcium Chloride results in increased cleavage of CASP9 protein] 		CTD PMID:36731150 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Casr calcium-sensing receptor multiple interactions
increases activity 		ISO Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein]
Calcium Chloride results in increased activity of CASR protein 		CTD PMID:16316325 PMID:17376781 NCBI chr11:77,738,398...77,813,639
Ensembl chr11:77,740,614...77,810,167 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases phosphorylation
multiple interactions
increases expression 		ISO Calcium Chloride results in increased phosphorylation of CCL2 protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CCL2 protein]; Resveratrol inhibits the reaction [Calcium Chloride results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Calcium Chloride results in increased phosphorylation of CCL2 protein]
Calcium Chloride results in increased expression of CCL2 mRNA; Calcium Chloride results in increased expression of CCL2 protein 		CTD PMID:21530968 PMID:22728078 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A decreases expression ISO Calcium Chloride results in decreased expression of CCT6A protein CTD PMID:25824407 NCBI chr12:32,508,842...32,519,072
Ensembl chr12:32,508,675...32,519,119 		JBrowse link
G Cd68 Cd68 molecule multiple interactions
increases expression 		ISO resveratrol inhibits the reaction [Calcium Chloride results in increased expression of CD68 mRNA] CTD PMID:21530968 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN1B protein] CTD PMID:12189186 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A mRNA]; Calcium Chloride inhibits the reaction [Azoxymethane results in decreased expression of CDKN2A protein] CTD PMID:12189186 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases activity ISO Calcium Chloride results in increased activity of CEBPA protein CTD PMID:17214633 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309 		JBrowse link
G Clec3b C-type lectin domain family 3, member B increases expression ISO Calcium Chloride results in increased expression of CLEC3B protein CTD PMID:25824407 NCBI chr 8:131,687,575...131,693,292 JBrowse link
G Clic3 chloride intracellular channel 3 decreases expression ISO Calcium Chloride results in decreased expression of CLIC3 protein CTD PMID:25824407 NCBI chr 3:28,670,176...28,672,166
Ensembl chr 3:28,670,229...28,675,723 		JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 increases expression ISO Calcium Chloride results in increased expression of CMTM6 protein CTD PMID:25824407 NCBI chr 8:123,301,131...123,319,230
Ensembl chr 8:123,300,918...123,319,230 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Calcium Chloride results in increased expression of COL1A1 mRNA CTD PMID:25824407 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain increases expression ISO Calcium Chloride results in increased expression of COL8A1 protein CTD PMID:25824407 NCBI chr11:56,245,998...56,378,586
Ensembl chr11:56,369,868...56,376,229 		JBrowse link
G Cops3 COP9 signalosome subunit 3 increases expression ISO Calcium Chloride results in increased expression of COPS3 protein CTD PMID:25824407 NCBI chr10:45,117,664...45,151,868
Ensembl chr10:45,117,657...45,152,074 		JBrowse link
G Cst3 cystatin C increases expression ISO Calcium Chloride results in increased expression of CST3 protein CTD PMID:25824407 NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937 		JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 decreases expression ISO Calcium Chloride results in decreased expression of CTHRC1 protein CTD PMID:25824407 NCBI chr 7:72,007,372...72,017,654
Ensembl chr 7:72,007,372...72,017,654 		JBrowse link
G Ctsb cathepsin B increases expression
multiple interactions 		ISO Calcium Chloride results in increased expression of CTSB protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CTSB protein] 		CTD PMID:22728078 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478 		JBrowse link
G Ctsk cathepsin K increases expression
multiple interactions 		ISO Calcium Chloride results in increased expression of CTSK protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CTSK protein] 		CTD PMID:22728078 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582 		JBrowse link
G Dcn decorin decreases expression ISO Calcium Chloride results in decreased expression of DCN protein CTD PMID:25824407 NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926 		JBrowse link
G Ddx39b DExD-box helicase 39B increases expression ISO Calcium Chloride results in increased expression of DDX39B protein CTD PMID:25824407 NCBI chr20:3,577,200...3,589,651
Ensembl chr20:3,576,734...3,589,651 		JBrowse link
G Ehd2 EH-domain containing 2 increases expression ISO Calcium Chloride results in increased expression of EHD2 protein CTD PMID:25824407 NCBI chr 1:85,767,757...85,786,974
Ensembl chr 1:85,768,667...85,786,943 		JBrowse link
G F10 coagulation factor X multiple interactions ISO [F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein; aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; nothofagin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] CTD PMID:25325928 NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280 		JBrowse link
G F11 coagulation factor XI multiple interactions ISO [F11 protein co-treated with Calcium Chloride] results in increased activity of F9 protein CTD PMID:6604052 NCBI chr16:53,720,502...53,741,547
Ensembl chr16:53,718,621...53,740,941 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO [F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein; aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; nothofagin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] CTD PMID:25325928 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G F5 coagulation factor V multiple interactions ISO [F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein; aspalathin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein]; nothofagin inhibits the reaction [[F5 protein co-treated with F10 protein co-treated with Calcium Chloride] results in increased metabolism of F2 protein] CTD PMID:25325928 NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247 		JBrowse link
G F9 coagulation factor IX multiple interactions ISO [F11 protein co-treated with Calcium Chloride] results in increased activity of F9 protein CTD PMID:6604052 NCBI chr  X:143,388,642...143,433,143
Ensembl chr  X:143,388,621...143,433,146 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Calcium Chloride results in increased expression of FYN protein CTD PMID:25824407 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G Git1 GIT ArfGAP 1 increases expression ISO Calcium Chloride results in increased expression of GIT1 protein CTD PMID:25824407 NCBI chr10:62,840,165...62,854,508
Ensembl chr10:62,840,394...62,854,508 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions EXP [manganese chloride co-treated with Calcium Chloride] results in increased secretion of GNRH1 protein CTD PMID:18603625 NCBI chr15:46,147,878...46,152,086
Ensembl chr15:46,148,301...46,148,977
Ensembl chr15:46,148,301...46,148,977 		JBrowse link
G Gpr89b G protein-coupled receptor 89B increases expression ISO Calcium Chloride results in increased expression of GPR89B protein CTD PMID:25824407 NCBI chr 2:187,096,970...187,134,391
Ensembl chr 2:187,080,020...187,134,391 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression 		ISO Quercetin inhibits the reaction [Calcium Chloride results in increased expression of GPX1 mRNA]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of GPX1 mRNA] CTD PMID:21530968 PMID:24337353 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions
increases expression 		ISO Quercetin inhibits the reaction [Calcium Chloride results in increased expression of GPX3 mRNA]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of GPX3 mRNA] CTD PMID:21530968 PMID:24337353 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Calcium Chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:21443188 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Htra1 HtrA serine peptidase 1 decreases expression ISO Calcium Chloride results in decreased expression of HTRA1 protein CTD PMID:25824407 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions 		ISO Calcium Chloride results in increased expression of ICAM1 mRNA
resveratrol inhibits the reaction [Calcium Chloride results in increased expression of ICAM1 mRNA] 		CTD PMID:21530968 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ift27 intraflagellar transport 27 increases expression ISO Calcium Chloride results in increased expression of IFT27 protein CTD PMID:25824407 NCBI chr 7:111,619,145...111,635,129
Ensembl chr 7:111,619,077...111,634,936 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions 		ISO
EXP 		Calcium Chloride results in increased expression of IL1B protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of IL1B protein] 		CTD PMID:22728078 PMID:36731150 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO Calcium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO Calcium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr17:73,285,281...73,321,555
Ensembl chr17:73,285,270...73,321,547 		JBrowse link
G Klk8 kallikrein related-peptidase 8 increases activity ISO Calcium Chloride results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr 1:103,388,352...103,395,195
Ensembl chr 1:103,388,352...103,395,195 		JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression ISO Calcium Chloride results in increased expression of LASP1 protein CTD PMID:25824407 NCBI chr10:83,290,820...83,331,989
Ensembl chr10:83,290,865...83,331,988 		JBrowse link
G Lrrfip1 LRR binding FLII interacting protein 1 decreases expression ISO Calcium Chloride results in decreased expression of LRRFIP1 protein CTD PMID:25824407 NCBI chr 9:99,039,590...99,167,805
Ensembl chr 9:99,039,614...99,167,779 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions 		EXP Calcium Chloride results in increased phosphorylation of MAPK1 protein
[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK1 protein; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK1 protein] 		CTD PMID:21215118 PMID:33621091 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression
increases phosphorylation
multiple interactions 		ISO
EXP 		Calcium Chloride results in increased expression of MAPK3 protein
Calcium Chloride results in increased phosphorylation of MAPK3 protein
[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK3 protein; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of MAPK3 protein] 		CTD PMID:21215118 PMID:25824407 PMID:33621091 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
multiple interactions
increases activity 		EXP
ISO 		Calcium Chloride results in increased expression of MMP2 mRNA; Calcium Chloride results in increased expression of MMP2 protein
Calcium Chloride inhibits the reaction [2,3-dihydroxybenzoic acid results in decreased activity of MMP2 protein]; Calcium Chloride inhibits the reaction [Deferoxamine results in decreased activity of MMP2 protein]; Calcium Chloride inhibits the reaction [Ferrichrome results in decreased activity of MMP2 protein]; Calcium Chloride inhibits the reaction [rhodotorulic acid results in decreased activity of MMP2 protein]
Quercetin inhibits the reaction [Calcium Chloride results in increased activity of MMP2 protein]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP2 mRNA]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP2 protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased activity of MMP2 protein] 		CTD PMID:10086886 PMID:16159824 PMID:20621845 PMID:21530968 PMID:22728078 More... NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions
increases activity 		EXP
ISO 		Calcium Chloride results in increased expression of MMP9 mRNA; Calcium Chloride results in increased expression of MMP9 protein
Quercetin inhibits the reaction [Calcium Chloride results in increased activity of MMP9 protein]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP9 mRNA]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of MMP9 protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased activity of MMP9 protein] 		CTD PMID:20621845 PMID:21530968 PMID:22728078 PMID:24337353 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP Calcium Chloride inhibits the reaction [Azoxymethane results in increased expression of MYC mRNA]; Calcium Chloride inhibits the reaction [Azoxymethane results in increased expression of MYC protein] CTD PMID:12189186 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression
multiple interactions 		ISO Calcium Chloride results in increased expression of NCF1 mRNA; Calcium Chloride results in increased expression of NCF1 protein
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of NCF1 mRNA]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of NCF1 protein] 		CTD PMID:24337353 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP Calcium Chloride promotes the reaction [NOS1 protein results in increased reduction of Trinitrotoluene] CTD PMID:15223068 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions 		ISO Calcium Chloride results in increased expression of NOS2 mRNA
Quercetin inhibits the reaction [Calcium Chloride results in increased expression of NOS2 mRNA] 		CTD PMID:24337353 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nt5c 5', 3'-nucleotidase, cytosolic increases expression ISO Calcium Chloride results in increased expression of NT5C protein CTD PMID:25824407 NCBI chr10:101,238,552...101,240,666
Ensembl chr10:101,238,576...101,240,865 		JBrowse link
G Nxn nucleoredoxin increases expression ISO Calcium Chloride results in increased expression of NXN protein CTD PMID:25824407 NCBI chr10:61,607,557...61,745,807
Ensembl chr10:61,607,568...61,745,807 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO Calcium Chloride promotes the reaction [PON1 protein results in increased hydrolysis of Paraoxon] CTD PMID:16052486 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
G Postn periostin decreases expression ISO Calcium Chloride results in decreased expression of POSTN protein CTD PMID:25824407 NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300 		JBrowse link
G Ppid peptidylprolyl isomerase D increases expression ISO Calcium Chloride results in increased expression of PPID mRNA; Calcium Chloride results in increased expression of PPID protein CTD PMID:18614807 NCBI chr 2:167,025,985...167,037,998
Ensembl chr 2:167,025,931...167,054,493 		JBrowse link
G Psen2 presenilin 2 increases expression ISO Calcium Chloride results in increased expression of PSEN2 protein CTD PMID:25824407 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:94,499,928...94,525,116 		JBrowse link
G Rad50 RAD50 double strand break repair protein decreases expression ISO Calcium Chloride results in decreased expression of RAD50 protein CTD PMID:25824407 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs increases expression ISO Calcium Chloride results in increased expression of RECK protein CTD PMID:25824407 NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:62,898,668...62,965,270 		JBrowse link
G S100a13 S100 calcium binding protein A13 multiple interactions ISO [Calcium Chloride co-treated with cuprous chloride] binds to and affects the folding of S100A13 protein; Calcium Chloride binds to and affects the folding of S100A13 protein CTD PMID:16766622 NCBI chr 2:178,297,020...178,303,514
Ensembl chr 2:178,296,917...178,303,507 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Calcium Chloride results in increased expression of S100A8 mRNA; Calcium Chloride results in increased expression of S100A8 protein CTD PMID:17214633 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Calcium Chloride results in increased expression of S100A9 mRNA; Calcium Chloride results in increased expression of S100A9 protein CTD PMID:17214633 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870 		JBrowse link
G Shc1 SHC adaptor protein 1 increases expression ISO Calcium Chloride results in increased expression of SHC1 protein CTD PMID:25824407 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Sod2 superoxide dismutase 2 increases activity
multiple interactions 		ISO Calcium Chloride results in increased activity of SOD2 protein
Quercetin inhibits the reaction [Calcium Chloride results in increased activity of SOD2 protein] 		CTD PMID:24337353 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 decreases expression ISO Calcium Chloride results in decreased expression of STAT6 protein CTD PMID:25824407 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
G Syn1 synapsin I multiple interactions EXP [4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of SYN1 protein; typhaneoside inhibits the reaction [[4-Aminopyridine co-treated with Calcium Chloride] results in increased phosphorylation of SYN1 protein] CTD PMID:33621091 NCBI chr  X:3,725,745...3,780,940
Ensembl chr  X:3,725,714...3,780,938 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO Calcium Chloride results in decreased expression of TGFB1 protein CTD PMID:25824407 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression
multiple interactions 		ISO Calcium Chloride results in decreased expression of TIMP1 mRNA
Quercetin inhibits the reaction [Calcium Chloride results in decreased expression of TIMP1 mRNA] 		CTD PMID:22728078 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression 		ISO
EXP 		Quercetin inhibits the reaction [Calcium Chloride results in increased expression of TNF protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of TNF mRNA]
Calcium Chloride results in increased expression of TNF mRNA; Calcium Chloride results in increased expression of TNF protein
Calcium Chloride inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]
cordycepin inhibits the reaction [Calcium Chloride results in increased expression of TNF protein] 		CTD PMID:21530968 PMID:22728078 PMID:36416909 PMID:36731150 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO Calcium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; Calcium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 3:56,911,398...56,930,797
Ensembl chr 3:56,911,252...56,930,796 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity 		ISO
EXP 		Calcium Chloride inhibits the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]; Ionomycin promotes the reaction [Calcium Chloride inhibits the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]]
Calcium Chloride results in increased activity of TRPV1 protein
Ionomycin inhibits the reaction [Calcium Chloride results in increased activity of TRPV1 protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Calcium Chloride results in increased activity of TRPV1 protein]; resiniferatoxin promotes the reaction [Calcium Chloride results in increased activity of TRPV1 protein] 		CTD PMID:19553475 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Ube3b ubiquitin protein ligase E3B multiple interactions ISO Calcium Chloride inhibits the reaction [CALM3 protein binds to and results in decreased activity of UBE3B protein] CTD PMID:28003368 NCBI chr12:47,844,368...47,890,702
Ensembl chr12:47,844,369...47,890,702 		JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 decreases phosphorylation
multiple interactions 		EXP Calcium Chloride results in decreased phosphorylation of UQCRFS1 protein
[oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein; [tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein; Cyclosporine inhibits the reaction [[oxophenylarsine co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein]; Cyclosporine inhibits the reaction [[tert-Butylhydroperoxide co-treated with Calcium Chloride] results in decreased phosphorylation of UQCRFS1 protein] 		CTD PMID:16023995 NCBI chr17:34,173,787...34,190,952
Ensembl chr17:34,173,833...34,190,950 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions 		ISO Calcium Chloride results in increased expression of VEGFA mRNA
resveratrol inhibits the reaction [Calcium Chloride results in increased expression of VEGFA mRNA] 		CTD PMID:21530968 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      application 20572
        NMR chemical shift reference compound 4426
          calcium dichloride 83
            calcium chloride dihydrate 0
            calcium chloride hexahydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    main group molecular entity 20809
                      s-block molecular entity 20147
                        alkaline earth molecular entity 916
                          calcium molecular entity 771
                            elemental calcium 769
                              calcium ion 373
                                calcium cation 372
                                  calcium(2+) 372
                                    calcium salt 372
                                      calcium dichloride 83
                                        calcium chloride dihydrate 0
                                        calcium chloride hexahydrate 0
paths to the root