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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phloretic acid
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Accession:CHEBI:32980 term browser browse the term
Definition:A hydroxy monocarboxylic acid consisting of propionic acid having a 4-hydroxyphenyl group at the 3-position.
Synonyms:exact_synonym: 3-(4-hydroxyphenyl)propanoic acid
 related_synonym: 3-(4-Hydroxyphenyl)propionic acid;   3-(p-hydroxyphenyl)propionic acid;   4-Hydroxyphenylpropionic acid;   Dihydro-p-coumaric acid;   Formula=C9H10O3;   HYDROXYPHENYL PROPIONIC ACID;   InChI=1S/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12);   InChIKey=NMHMNPHRMNGLLB-UHFFFAOYSA-N;   Phloretinic acid;   SMILES=OC(=O)CCc1ccc(O)cc1;   beta-(p-hydroxyphenyl)propionic acid;   desaminotyrosine;   p-Hydroxyhydrocinnamic acid;   p-hydroxyphenylpropionic acid
 alt_id: CHEBI:19934;   CHEBI:43113;   CHEBI:8110
 xref: Beilstein:2209841;   CAS:501-97-3;   DrugBank:DB03897;   HMDB:HMDB0002199;   KEGG:C01744;   KNApSAcK:C00029471
 xref_mesh: MESH:C008869
 xref: PDBeChem:HPP;   PMID:1623136;   PMID:16656273;   PMID:17190852;   PMID:19176242;   PMID:21109029;   PMID:21141880;   PMID:5354935;   PMID:6531939;   Reaxys:2209841
 cyclic_relationship: is_conjugate_acid_of CHEBI:16331


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phloretic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO phloretic acid results in decreased expression of PTGS2 protein CTD PMID:16177193 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      application 19426
        pharmaceutical 19301
          drug 19301
            antifungal drug 5144
              propionic acid 3670
                phloretic acid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        monocarboxylic acid 17476
                                          fatty acid 15990
                                            saturated fatty acid 15965
                                              propionic acid 3670
                                                phloretic acid 1
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