CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: octadecane
Accession: CHEBI:32926
browse the term
Definition: A straight-chain alkane carrying 18 carbon atoms.
Synonyms: related_synonym: CH3-[CH2]16-CH3; Formula=C18H38; InChI=1S/C18H38/c1-3-5-7-9-11-13-15-17-18-16-14-12-10-8-6-4-2/h3-18H2,1-2H3; InChIKey=RZJRJXONCZWCBN-UHFFFAOYSA-N; Oktadekan; SMILES=CCCCCCCCCCCCCCCCCC; n-octadecane
xref: Beilstein:1740138; CAS:593-45-3; Gmelin:263389; KNApSAcK:C00030879; PMID:9842728; Reaxys:1740138
G
Lipc
lipase C, hepatic type
multiple interactions decreases abundance
ISO
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol
CTD
PMID:24777581
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lipg
lipase G, endothelial type
decreases abundance multiple interactions
ISO
LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol
CTD
PMID:24777581
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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Col1a1
collagen type I alpha 1 chain
multiple interactions
ISO
1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]
CTD
PMID:27936102
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Dagla
diacylglycerol lipase, alpha
increases metabolic processing
ISO
DAGLA protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol
CTD
PMID:18657971
NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
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Daglb
diacylglycerol lipase, beta
increases metabolic processing
ISO
DAGLB protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol
CTD
PMID:18657971
NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
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Dgke
diacylglycerol kinase epsilon
increases phosphorylation
ISO
DGKE protein results in increased phosphorylation of 1-stearoyl-2-arachidonoylglycerol
CTD
PMID:17455907
NCBI chr10:73,853,030...73,877,334
Ensembl chr10:73,855,583...73,877,100
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Ppargc1a
PPARG coactivator 1 alpha
increases expression
ISO
1-stearoyl-2-arachidonoylglycerol results in increased expression of PPARGC1A mRNA
CTD
PMID:23056435
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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Tgfb1
transforming growth factor, beta 1
multiple interactions
ISO
1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]
CTD
PMID:27936102
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Trpm6
transient receptor potential cation channel, subfamily M, member 6
multiple interactions
ISO
TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Calcium]
CTD
PMID:11988098
NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
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Lipc
lipase C, hepatic type
decreases abundance
ISO
LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol
CTD
PMID:24777581
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lipg
lipase G, endothelial type
decreases abundance
ISO
LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol
CTD
PMID:24777581
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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Lipc
lipase C, hepatic type
multiple interactions
ISO
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of stearoyl alpha-lysolecithin
CTD
PMID:24777581
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lipg
lipase G, endothelial type
multiple interactions
ISO
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of stearoyl alpha-lysolecithin
CTD
PMID:24777581
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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Adtrp
androgen-dependent TFPI-regulating protein
affects chemical synthesis
ISO
ADTRP protein affects the chemical synthesis of 9-hydroxystearic acid
CTD
PMID:32152231
NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826
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Aig1
androgen-induced 1
affects chemical synthesis
ISO
AIG1 protein affects the chemical synthesis of 9-hydroxystearic acid
CTD
PMID:32152231
NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084
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Lipg
lipase G, endothelial type
decreases abundance
ISO
LIPG gene mutant form results in decreased abundance of cholesterol stearate
CTD
PMID:24777581
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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Abcg8
ATP binding cassette subfamily G member 8
affects expression
EXP
Corn Oil affects the expression of ABCG8 mRNA
CTD
PMID:16360708
NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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Acaca
acetyl-CoA carboxylase alpha
increases expression
EXP
Corn Oil results in increased expression of ACACA mRNA
CTD
PMID:1973097
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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Acly
ATP citrate lyase
affects expression
EXP
Corn Oil affects the expression of ACLY mRNA
CTD
PMID:16360708
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Acot2
acyl-CoA thioesterase 2
affects expression
EXP
Corn Oil affects the expression of ACOT2 mRNA
CTD
PMID:16360708
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions
EXP
Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein]
CTD
PMID:29165388
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Akr1b7
aldo-keto reductase family 1, member B7
affects expression
EXP
Corn Oil affects the expression of AKR1B7 mRNA
CTD
PMID:16360708
NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression
EXP
Corn Oil affects the expression of ALDH1A1 mRNA
CTD
PMID:16360708
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Angptl4
angiopoietin-like 4
affects expression
EXP
Corn Oil affects the expression of ANGPTL4 mRNA
CTD
PMID:16360708
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Areg
amphiregulin
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of AREG mRNA
CTD
PMID:32186404
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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Bad
BCL2-associated agonist of cell death
increases expression
EXP
Corn Oil results in increased expression of BAD mRNA
CTD
PMID:22760963
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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Bdkrb1
bradykinin receptor B1
multiple interactions
EXP
Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein]
CTD
PMID:29165388
NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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Bhlhe40
basic helix-loop-helix family, member e40
affects expression
EXP
Corn Oil affects the expression of BHLHE40 mRNA
CTD
PMID:16360708
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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Bhmt
betaine-homocysteine S-methyltransferase
affects expression
EXP
Corn Oil affects the expression of BHMT mRNA
CTD
PMID:16360708
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Birc3
baculoviral IAP repeat-containing 3
increases expression
ISO
Corn Oil results in increased expression of BIRC3 mRNA
CTD
PMID:33263755
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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Bmp1
bone morphogenetic protein 1
affects expression
EXP
Corn Oil affects the expression of BMP1 mRNA
CTD
PMID:16360708
NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
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Bmp2
bone morphogenetic protein 2
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of BMP2 mRNA
CTD
PMID:32186404
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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Cadm1
cell adhesion molecule 1
affects expression
EXP
Corn Oil affects the expression of CADM1 mRNA
CTD
PMID:16360708
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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Calca
calcitonin-related polypeptide alpha
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of CALCA mRNA
CTD
PMID:32186404
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Car6
carbonic anhydrase 6
increases expression
ISO
Corn Oil results in increased expression of CAR6 mRNA
CTD
PMID:33263755
NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
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Card9
caspase recruitment domain family, member 9
increases expression
ISO
Corn Oil results in increased expression of CARD9 mRNA
CTD
PMID:33263755
NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
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Cat
catalase
multiple interactions decreases expression
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in decreased expression of CAT protein Corn Oil results in decreased expression of CAT protein
CTD
PMID:36432690
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cav3
caveolin 3
decreases expression
ISO
Corn Oil results in decreased expression of CAV3 mRNA
CTD
PMID:33263755
NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
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Ccl3
C-C motif chemokine ligand 3
increases expression decreases expression
ISO EXP
Corn Oil results in increased expression of CCL3 mRNA Corn Oil results in decreased expression of CCL3 mRNA
CTD
PMID:22760963 PMID:23409006
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccnd1
cyclin D1
affects expression
EXP
Corn Oil affects the expression of CCND1 mRNA
CTD
PMID:16360708
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Cd36
CD36 molecule
decreases expression
EXP
Corn Oil results in decreased expression of CD36 mRNA
CTD
PMID:22760963
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cdhr1
cadherin-related family member 1
increases expression
EXP
Corn Oil results in increased expression of CDHR1 mRNA
CTD
PMID:22760963
NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
affects expression increases expression
EXP
Corn Oil affects the expression of CDKN1A mRNA Corn Oil results in increased expression of CDKN1A mRNA
CTD
PMID:16360708 PMID:22760963
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cenpt
centromere protein T
increases expression
EXP
Corn Oil results in increased expression of CENPT mRNA
CTD
PMID:22760963
NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142
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Cfb
complement factor B
increases expression
EXP
Corn Oil results in increased expression of CFB mRNA
CTD
PMID:22760963
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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Cldn1
claudin 1
decreases expression
ISO
Corn Oil results in decreased expression of CLDN1 mRNA
CTD
PMID:33263755
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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Cldn9
claudin 9
increases expression
ISO
Corn Oil results in increased expression of CLDN9 mRNA
CTD
PMID:33263755
NCBI chr10:12,714,137...12,715,568
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Cox7a1
cytochrome c oxidase subunit 7A1
decreases expression
ISO
Corn Oil results in decreased expression of COX7A1 mRNA
CTD
PMID:23409006
NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151
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Cpt1a
carnitine palmitoyltransferase 1A
increases expression multiple interactions affects expression
EXP ISO
Corn Oil results in increased expression of CPT1A mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT1A mRNA Corn Oil affects the expression of CPT1A mRNA
CTD
PMID:16360708 PMID:22760963 PMID:36432690
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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Cpt2
carnitine palmitoyltransferase 2
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT2 mRNA
CTD
PMID:36432690
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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Crot
carnitine O-octanoyltransferase
affects expression multiple interactions
EXP ISO
Corn Oil affects the expression of CROT mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CROT mRNA
CTD
PMID:16360708 PMID:36432690
NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
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Ctsg
cathepsin G
increases expression
EXP
Corn Oil results in increased expression of CTSG mRNA
CTD
PMID:22760963
NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
affects expression
EXP
Corn Oil affects the expression of CYP17A1 mRNA
CTD
PMID:16360708
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
affects expression
EXP
Corn Oil affects the expression of CYP7A1 mRNA
CTD
PMID:16360708
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Cyp8b1
cytochrome P450 family 8 subfamily B member 1
affects expression
EXP
Corn Oil affects the expression of CYP8B1 mRNA
CTD
PMID:16360708
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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Ephx2
epoxide hydrolase 2
affects expression
EXP
Corn Oil affects the expression of EPHX2 mRNA
CTD
PMID:16360708
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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Ets1
ETS proto-oncogene 1, transcription factor
decreases expression
EXP
Corn Oil results in decreased expression of ETS1 mRNA
CTD
PMID:22760963
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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Fabp1
fatty acid binding protein 1
multiple interactions
EXP
[Ethanol co-treated with Corn Oil] results in decreased expression of FABP1 mRNA
CTD
PMID:15016835
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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Fabp2
fatty acid binding protein 2
affects expression
EXP
Corn Oil affects the expression of FABP2 mRNA
CTD
PMID:16360708
NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
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Fabp7
fatty acid binding protein 7
affects expression
EXP
Corn Oil affects the expression of FABP7 mRNA
CTD
PMID:16360708
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
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Fasn
fatty acid synthase
affects expression
EXP
Corn Oil affects the expression of FASN mRNA
CTD
PMID:16360708
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Fcgrt
Fc gamma receptor and transporter
decreases expression
EXP
Corn Oil results in decreased expression of FCGRT mRNA
CTD
PMID:22760963
NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084
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Fgb
fibrinogen beta chain
affects expression
EXP
Corn Oil affects the expression of FGB mRNA
CTD
PMID:16360708
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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Fgf21
fibroblast growth factor 21
affects expression
EXP
Corn Oil affects the expression of FGF21 mRNA
CTD
PMID:16360708
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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Fst
follistatin
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of FST mRNA
CTD
PMID:32186404
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
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G0s2
G0/G1switch 2
affects expression
EXP
Corn Oil affects the expression of G0S2 mRNA
CTD
PMID:16360708
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
affects expression
EXP
Corn Oil affects the expression of GADD45A mRNA
CTD
PMID:16360708
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gal
galanin and GMAP prepropeptide
increases expression
EXP
Corn Oil results in increased expression of GAL mRNA
CTD
PMID:22760963
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
G
Gck
glucokinase
affects expression
EXP
Corn Oil affects the expression of GCK mRNA
CTD
PMID:16360708
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Gjd2
gap junction protein, delta 2
increases expression
ISO
Corn Oil results in increased expression of GJD2 mRNA
CTD
PMID:33263755
NCBI chr 3:100,771,450...100,776,134
Ensembl chr 3:100,772,062...100,775,061
G
Got1
glutamic-oxaloacetic transaminase 1
affects expression
EXP
Corn Oil affects the expression of GOT1 mRNA
CTD
PMID:16360708
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Got2
glutamic-oxaloacetic transaminase 2
decreases expression
EXP
Corn Oil results in decreased expression of GOT2 mRNA
CTD
PMID:34987138
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
G
Gpd2
glycerol-3-phosphate dehydrogenase 2
affects expression
EXP
Corn Oil affects the expression of GPD2 mRNA
CTD
PMID:16360708
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
EXP
[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein; Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]; Orlistat inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]
CTD
PMID:29479035
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
H2ac25
H2A clustered histone 25
affects expression
EXP
Corn Oil affects the expression of H2A mRNA
CTD
PMID:16360708
NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874
G
Hal
histidine ammonia lyase
affects expression
EXP
Corn Oil affects the expression of HAL mRNA
CTD
PMID:16360708
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
G
Hamp
hepcidin antimicrobial peptide
affects expression
EXP
Corn Oil affects the expression of HAMP mRNA
CTD
PMID:16360708
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
affects expression
EXP
Corn Oil affects the expression of HMGCR mRNA
CTD
PMID:16360708
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Hoxa11
homeobox A11
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of HOXA11 mRNA
CTD
PMID:32186404
NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
G
Hp
haptoglobin
increases expression
EXP
Corn Oil results in increased expression of HP mRNA
CTD
PMID:22760963
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
Corn Oil results in increased expression of HSP90AA1 mRNA
CTD
PMID:33263755
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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Idi1
isopentenyl-diphosphate delta isomerase 1
affects expression
EXP
Corn Oil affects the expression of IDI1 mRNA
CTD
PMID:16360708
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
affects expression increases expression
EXP
Corn Oil affects the expression of IGF2BP2 mRNA Corn Oil results in increased expression of IGF2BP2 mRNA
CTD
PMID:22760963
NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
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Igfbp1
insulin-like growth factor binding protein 1
affects expression
EXP
Corn Oil affects the expression of IGFBP1 mRNA
CTD
PMID:16360708
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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Ihh
Indian hedgehog signaling molecule
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of IHH mRNA
CTD
PMID:32186404
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
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Il12b
interleukin 12B
increases secretion
EXP
Corn Oil results in increased secretion of IL12B protein
CTD
PMID:33263755
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Il18
interleukin 18
increases expression
ISO
Corn Oil results in increased expression of IL18 mRNA
CTD
PMID:33263755
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1a
interleukin 1 alpha
increases secretion
EXP
Corn Oil results in increased secretion of IL1A protein
CTD
PMID:33263755
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
increases secretion
EXP
Corn Oil results in increased secretion of IL1B protein
CTD
PMID:33263755
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1rn
interleukin 1 receptor antagonist
increases expression
EXP
Corn Oil results in increased expression of IL1RN mRNA
CTD
PMID:22760963
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Il4
interleukin 4
increases expression increases secretion decreases expression
ISO EXP
Corn Oil results in increased expression of IL4 mRNA Corn Oil results in increased secretion of IL4 protein Corn Oil results in decreased expression of IL4 mRNA
CTD
PMID:23409006 PMID:33263755
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6r
interleukin 6 receptor
increases expression
EXP
Corn Oil results in increased expression of IL6R mRNA
CTD
PMID:22760963
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
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Il9
interleukin 9
increases secretion
EXP
Corn Oil results in increased secretion of IL9 protein
CTD
PMID:33263755
NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
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Inhbe
inhibin subunit beta E
affects expression
EXP
Corn Oil affects the expression of INHBE mRNA
CTD
PMID:16360708
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
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Ins1
insulin 1
multiple interactions
EXP
Corn Oil inhibits the reaction [Glucose results in increased expression of INS1 protein]
CTD
PMID:29165388
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
G
Irak1
interleukin-1 receptor-associated kinase 1
increases expression
ISO
Corn Oil results in increased expression of IRAK1 mRNA
CTD
PMID:33263755
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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Irf5
interferon regulatory factor 5
increases expression
ISO
Corn Oil results in increased expression of IRF5 mRNA
CTD
PMID:33263755
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
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Irf7
interferon regulatory factor 7
increases expression
ISO
Corn Oil results in increased expression of IRF7 mRNA
CTD
PMID:33263755
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Corn Oil results in increased expression of JUN mRNA
CTD
PMID:33263755
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Klf2
KLF transcription factor 2
affects expression
EXP
Corn Oil affects the expression of KLF2 mRNA
CTD
PMID:16360708
NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
G
Lcat
lecithin cholesterol acyltransferase
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of LCAT mRNA
CTD
PMID:36432690
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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Lcn2
lipocalin 2
increases expression
EXP
Corn Oil results in increased expression of LCN2 mRNA
CTD
PMID:22760963
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Lep
leptin
multiple interactions
EXP
Corn Oil inhibits the reaction [Glucose results in increased expression of LEP protein]
CTD
PMID:29165388
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lgals1
galectin 1
increases expression
EXP
Corn Oil results in increased expression of LGALS1 mRNA
CTD
PMID:22760963
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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Lox
lysyl oxidase
multiple interactions
ISO
Corn Oil results in increased activity of and results in increased cleavage of LOX protein
CTD
PMID:26240151
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
G
Ly75
lymphocyte antigen 75
increases expression
EXP
Corn Oil results in increased expression of LY75 mRNA
CTD
PMID:22760963
NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374
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Map2k1
mitogen activated protein kinase kinase 1
increases expression
ISO
Corn Oil results in increased expression of MAP2K1 mRNA
CTD
PMID:33263755
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Map2k3
mitogen activated protein kinase kinase 3
increases expression
ISO
Corn Oil results in increased expression of MAP2K3 mRNA
CTD
PMID:33263755
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
G
Map2k6
mitogen-activated protein kinase kinase 6
affects expression
EXP
Corn Oil affects the expression of MAP2K6 mRNA
CTD
PMID:16360708
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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Map3k7
mitogen activated protein kinase kinase kinase 7
increases expression
ISO
Corn Oil results in increased expression of MAP3K7 mRNA
CTD
PMID:33263755
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
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Mapk1
mitogen activated protein kinase 1
increases expression
ISO
Corn Oil results in increased expression of MAPK1 mRNA
CTD
PMID:33263755
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk14
mitogen activated protein kinase 14
increases expression
ISO
Corn Oil results in increased expression of MAPK14 mRNA
CTD
PMID:33263755
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
G
Mapk3
mitogen activated protein kinase 3
increases expression
ISO
Corn Oil results in increased expression of MAPK3 mRNA
CTD
PMID:33263755
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mdm2
MDM2 proto-oncogene
decreases expression
EXP
Corn Oil results in decreased expression of MDM2 mRNA
CTD
PMID:22760963
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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Mgmt
O-6-methylguanine-DNA methyltransferase
increases expression
EXP
Corn Oil results in increased expression of MGMT mRNA
CTD
PMID:22760963
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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Mgst2
microsomal glutathione S-transferase 2
increases expression
EXP
Corn Oil results in increased expression of MGST2 mRNA
CTD
PMID:22760963
NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
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Mlycd
malonyl-CoA decarboxylase
decreases expression
EXP
Corn Oil results in decreased expression of MLYCD mRNA
CTD
PMID:22760963
NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
G
Msmo1
methylsterol monooxygenase 1
affects expression
EXP
Corn Oil affects the expression of MSMO1 mRNA
CTD
PMID:16360708
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
G
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of MTR mRNA
CTD
PMID:36432690
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
G
Mx2
MX dynamin like GTPase 2
affects expression
EXP
Corn Oil affects the expression of MX2 mRNA
CTD
PMID:16360708
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
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Myd88
MYD88, innate immune signal transduction adaptor
increases expression
ISO
Corn Oil results in increased expression of MYD88 mRNA
CTD
PMID:33263755
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
G
Nfe2l2
NFE2 like bZIP transcription factor 2
decreases activity
ISO
Corn Oil results in decreased activity of NFE2L2 protein
CTD
PMID:30203046
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nfkbia
NFKB inhibitor alpha
increases expression
ISO
Corn Oil results in increased expression of NFKBIA mRNA
CTD
PMID:33263755
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
G
Nlrc4
NLR family, CARD domain containing 4
increases expression
ISO
Corn Oil results in increased expression of NLRC4 mRNA
CTD
PMID:33263755
NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
G
Nr1h4
nuclear receptor subfamily 1, group H, member 4
affects expression
EXP
Corn Oil affects the expression of NR1H4 mRNA
CTD
PMID:16360708
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
G
Nr4a2
nuclear receptor subfamily 4, group A, member 2
increases expression
EXP
Corn Oil results in increased expression of NR4A2 mRNA
CTD
PMID:22760963
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
G
Nsmce3
NSE3 homolog, SMC5-SMC6 complex component
affects expression
EXP
Corn Oil affects the expression of NSMCE3 mRNA
CTD
PMID:16360708
NCBI chr 1:118,401,302...118,402,629
G
Oat
ornithine aminotransferase
affects expression
EXP
Corn Oil affects the expression of OAT mRNA
CTD
PMID:16360708
NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
G
Osgin1
oxidative stress induced growth inhibitor 1
affects expression
EXP
Corn Oil affects the expression of OSGIN1 mRNA
CTD
PMID:16360708
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
G
P2rx5
purinergic receptor P2X 5
affects expression
EXP
Corn Oil affects the expression of P2RX5 mRNA
CTD
PMID:16360708
NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
G
Pax8
paired box 8
affects expression
EXP
Corn Oil affects the expression of PAX8 mRNA
CTD
PMID:16360708
NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
G
Pdgfa
platelet derived growth factor subunit A
affects expression
EXP
Corn Oil affects the expression of PDGFA mRNA
CTD
PMID:16360708
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
G
Pdgfrb
platelet derived growth factor receptor beta
increases expression
EXP
Corn Oil results in increased expression of PDGFRB mRNA
CTD
PMID:22760963
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
G
Pdlim1
PDZ and LIM domain 1
affects expression
EXP
Corn Oil affects the expression of PDLIM1 mRNA
CTD
PMID:16360708
NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
G
Pdlim2
PDZ and LIM domain 2
affects expression
EXP
Corn Oil affects the expression of PDLIM2 mRNA
CTD
PMID:16360708
NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
G
Pgf
placental growth factor
increases expression
EXP
Corn Oil results in increased expression of PGF mRNA
CTD
PMID:22760963
NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
G
Pgrmc2
progesterone receptor membrane component 2
affects expression
EXP
Corn Oil affects the expression of PGRMC2 mRNA
CTD
PMID:16360708
NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
increases expression
ISO
Corn Oil results in increased expression of PIK3CA mRNA
CTD
PMID:33263755
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
G
Plin2
perilipin 2
affects expression
EXP
Corn Oil affects the expression of PLIN2 mRNA
CTD
PMID:16360708
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Prlr
prolactin receptor
affects expression
EXP
Corn Oil affects the expression of PRLR mRNA
CTD
PMID:16360708
NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of PTGS2 mRNA
CTD
PMID:32186404
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptprf
protein tyrosine phosphatase, receptor type, F
affects expression
EXP
Corn Oil affects the expression of PTPRF mRNA
CTD
PMID:16360708
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
G
Pycard
PYD and CARD domain containing
increases expression
ISO
Corn Oil results in increased expression of PYCARD mRNA
CTD
PMID:33263755
NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
G
Rac1
Rac family small GTPase 1
increases expression
ISO
Corn Oil results in increased expression of RAC1 mRNA
CTD
PMID:33263755
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
G
Ripk1
receptor interacting serine/threonine kinase 1
increases expression
ISO
Corn Oil results in increased expression of RIPK1 mRNA
CTD
PMID:33263755
NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
G
Ripk2
receptor-interacting serine-threonine kinase 2
increases expression
ISO
Corn Oil results in increased expression of RIPK2 mRNA
CTD
PMID:33263755
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
G
RT1-A
RT1 class I, locus A
increases expression
EXP
Corn Oil results in increased expression of RT1-A mRNA
CTD
PMID:22760963
G
RT1-Bb
RT1 class II, locus Bb
increases expression
EXP
Corn Oil results in increased expression of RT1-BB mRNA
CTD
PMID:22760963
NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
G
RT1-CE11
RT1 class I, locus CE11
decreases expression
EXP
Corn Oil results in decreased expression of RT1-CE11 mRNA
CTD
PMID:22760963
NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362
G
RT1-CE14
RT1 class I, locus CE14
increases expression
EXP
Corn Oil results in increased expression of RT1-CE14 mRNA
CTD
PMID:22760963
NCBI chr20:3,296,654...3,300,795
Ensembl chr20:3,297,196...3,305,134
G
RT1-CE15
RT1 class I, locus CE15
decreases expression
EXP
Corn Oil results in decreased expression of RT1-CE15 mRNA
CTD
PMID:22760963
NCBI chr20:3,275,575...3,279,074
Ensembl chr20:3,264,172...3,279,563 Ensembl chr20:3,264,172...3,279,563
G
RT1-CE16
RT1 class I, locus CE16
increases expression
EXP
Corn Oil results in increased expression of RT1-CE16 mRNA
CTD
PMID:22760963
NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
G
RT1-CE2
RT1 class I, locus CE2
increases expression
EXP
Corn Oil results in increased expression of RT1-CE2 mRNA
CTD
PMID:22760963
NCBI chr20:3,538,452...3,541,841
Ensembl chr20:3,537,809...3,541,790
G
RT1-CE3
RT1 class I, locus CE3
increases expression
EXP
Corn Oil results in increased expression of RT1-CE3 mRNA
CTD
PMID:22760963
NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081
G
RT1-CE4
RT1 class I, locus CE4
increases expression
EXP
Corn Oil results in increased expression of RT1-CE4 mRNA
CTD
PMID:22760963
NCBI chr20:3,431,509...3,504,535
G
RT1-CE5
RT1 class I, locus CE5
increases expression
EXP
Corn Oil results in increased expression of RT1-CE5 mRNA
CTD
PMID:22760963
NCBI chr20:3,403,418...3,479,476
G
RT1-N1
RT1 class Ib, locus N1
decreases expression
EXP
Corn Oil results in decreased expression of RT1-N1 mRNA
CTD
PMID:22760963
G
S100a8
S100 calcium binding protein A8
increases expression
EXP
Corn Oil results in increased expression of S100A8 mRNA
CTD
PMID:22760963
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
G
S100a9
S100 calcium binding protein A9
increases expression
EXP
Corn Oil results in increased expression of S100A9 mRNA
CTD
PMID:22760963
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
G
Scd
stearoyl-CoA desaturase
affects expression
EXP
Corn Oil affects the expression of SCD1 mRNA
CTD
PMID:16360708
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Scn1b
sodium voltage-gated channel beta subunit 1
affects expression
EXP
Corn Oil affects the expression of SCN1B mRNA
CTD
PMID:16360708
NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
G
Sds
serine dehydratase
affects expression
EXP
Corn Oil affects the expression of SDS mRNA
CTD
PMID:16360708
NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
G
Sfrp2
secreted frizzled-related protein 2
decreases expression
EXP
Corn Oil results in decreased expression of SFRP2 mRNA
CTD
PMID:22760963
NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
G
Slc25a20
solute carrier family 25 member 20
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of SLC25A20 mRNA
CTD
PMID:36432690
NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
G
Slc25a25
solute carrier family 25 member 25
affects expression
EXP
Corn Oil affects the expression of SLC25A25 mRNA
CTD
PMID:16360708
NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
G
Sod1
superoxide dismutase 1
decreases activity multiple interactions
ISO
Corn Oil results in decreased activity of SOD1 protein [Corn Oil co-treated with Iron, Dietary] results in decreased activity of SOD1 protein; [Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]; Iron, Dietary promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]
CTD
PMID:17194920
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Sparc
secreted protein acidic and cysteine rich
increases expression
EXP
Corn Oil results in increased expression of SPARC mRNA
CTD
PMID:22760963
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
G
Sqle
squalene epoxidase
affects expression
EXP
Corn Oil affects the expression of SQLE mRNA
CTD
PMID:16360708
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
G
Srebf1
sterol regulatory element binding transcription factor 1
affects expression
EXP
Corn Oil affects the expression of SREBF1 mRNA
CTD
PMID:16360708
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
G
Sstr3
somatostatin receptor 3
decreases expression
EXP
Corn Oil results in decreased expression of SSTR3 mRNA
CTD
PMID:22760963
NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
G
Sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
increases expression
ISO
Corn Oil results in increased expression of SUGT1 mRNA
CTD
PMID:33263755
NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
G
Syk
spleen associated tyrosine kinase
increases expression
ISO
Corn Oil results in increased expression of SYK mRNA
CTD
PMID:23409006
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
G
Tac1
tachykinin, precursor 1
decreases expression
EXP
Corn Oil results in decreased expression of TAC1 mRNA
CTD
PMID:22760963
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
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Tat
tyrosine aminotransferase
affects expression
EXP
Corn Oil affects the expression of TAT mRNA
CTD
PMID:16360708
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
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Tbc1d14
TBC1 domain family, member 14
affects expression
EXP
Corn Oil affects the expression of TBC1D14 mRNA
CTD
PMID:16360708
NCBI chr14:74,172,652...74,272,182
Ensembl chr14:74,172,664...74,272,183
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Tgfa
transforming growth factor alpha
decreases expression
EXP
Corn Oil results in decreased expression of TGFA mRNA
CTD
PMID:22760963
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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Ticam1
TIR domain containing adaptor molecule 1
increases expression
ISO
Corn Oil results in increased expression of TICAM1 mRNA
CTD
PMID:33263755
NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
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Tjp2
tight junction protein 2
increases expression
ISO
Corn Oil results in increased expression of TJP2 mRNA
CTD
PMID:33263755
NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
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Tjp3
tight junction protein 3
increases expression
ISO
Corn Oil results in increased expression of TJP3 mRNA
CTD
PMID:33263755
NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
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Tnfrsf1a
TNF receptor superfamily member 1A
increases expression
ISO
Corn Oil results in increased expression of TNFRSF1A mRNA
CTD
PMID:33263755
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Tollip
toll interacting protein
increases expression
ISO
Corn Oil results in increased expression of TOLLIP mRNA
CTD
PMID:33263755
NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625
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Tpcn2
two pore segment channel 2
affects expression
EXP
Corn Oil affects the expression of TPCN2 mRNA
CTD
PMID:16360708
NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236
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Tpt1
tumor protein, translationally-controlled 1
increases expression
EXP
Corn Oil results in increased expression of TPT1 mRNA
CTD
PMID:22760963
NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
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Vegfb
vascular endothelial growth factor B
decreases expression
EXP
Corn Oil results in decreased expression of VEGFB mRNA
CTD
PMID:22760963
NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
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Vnn1
vanin 1
affects expression
EXP
Corn Oil affects the expression of VNN1 mRNA
CTD
PMID:16360708
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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Xiap
X-linked inhibitor of apoptosis
decreases expression
ISO
Corn Oil results in decreased expression of XIAP mRNA
CTD
PMID:33263755
NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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Xpnpep2
X-prolyl aminopeptidase 2
affects expression
EXP
Corn Oil affects the expression of XPNPEP2 mRNA
CTD
PMID:16360708
NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223
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Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
affects expression
EXP
Corn Oil affects the expression of ZDHHC23 mRNA
CTD
PMID:16360708
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
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Abcg1
ATP binding cassette subfamily G member 1
increases expression
ISO
stearic acid results in increased expression of ABCG1 mRNA
CTD
PMID:16730733
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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Adamts9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
increases expression
ISO
stearic acid results in increased expression of ADAMTS9 mRNA
CTD
PMID:32347412
NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
G
Adipoq
adiponectin, C1Q and collagen domain containing
decreases expression multiple interactions
ISO
stearic acid results in decreased expression of ADIPOQ mRNA resveratrol inhibits the reaction [stearic acid results in decreased expression of ADIPOQ mRNA]
CTD
PMID:17374693
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Agr2
anterior gradient 2, protein disulphide isomerase family member
increases expression
ISO
stearic acid results in increased expression of AGR2 mRNA
CTD
PMID:32347412
NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
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Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
stearic acid results in increased expression of AKR1C1 mRNA
CTD
PMID:32347412
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
stearic acid results in increased expression of AKR1C2 mRNA
CTD
PMID:32347412
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Alb
albumin
affects binding multiple interactions
ISO
ALB protein binds to stearic acid; stearic acid binds to ALB protein [[[stearic acid binds to ALB protein] which affects the susceptibility to Clozapine] which affects the reduction of Cysteine] which affects the activity of ALB protein; [[stearic acid binds to ALB protein] which affects the susceptibility to Clozapine] which affects the reduction of Cysteine; [ALB protein binds to stearic acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to stearic acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein]; [ALB protein modified form binds to stearic acid] which results in decreased reduction of Dithionitrobenzoic Acid; [stearic acid binds to ALB protein] which affects the susceptibility to Clozapine; stearic acid inhibits the reaction [Clozapine binds to ALB protein]; stearic acid inhibits the reaction [ziprasidone binds to ALB protein]
CTD
PMID:25451573 PMID:31400341
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
decreases expression
ISO
stearic acid results in decreased expression of ALDH1A1 protein
CTD
PMID:26739624
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Apoa4
apolipoprotein A4
increases expression
ISO
stearic acid results in increased expression of APOA4 mRNA
CTD
PMID:26739624
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
G
Ar
androgen receptor
multiple interactions
ISO
stearic acid binds to and results in decreased activity of AR protein
CTD
PMID:27633901
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Atg9b
autophagy related 9B
increases expression
ISO
stearic acid results in increased expression of ATG9B mRNA
CTD
PMID:32347412
NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:10,786,114...10,793,651
G
Becn1
beclin 1
multiple interactions
ISO
[stearic acid co-treated with Lipopolysaccharides] affects the expression of BECN1 protein
CTD
PMID:33810233
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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Casp3
caspase 3
multiple interactions
EXP
SCD1 protein inhibits the reaction [stearic acid results in increased activity of CASP3 protein]; stearic acid results in increased cleavage of and results in increased activity of CASP3 protein
CTD
PMID:22413010
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp7
caspase 7
increases activity
EXP
stearic acid results in increased activity of CASP7 protein
CTD
PMID:22413010
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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Cat
catalase
increases activity
EXP
stearic acid results in increased activity of CAT protein
CTD
PMID:17302992
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccl2
C-C motif chemokine ligand 2
multiple interactions increases expression
ISO
resveratrol inhibits the reaction [stearic acid results in increased expression of CCL2 mRNA]
CTD
PMID:17374693
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl3
C-C motif chemokine ligand 3
increases expression
ISO
stearic acid results in increased expression of CCL3 mRNA
CTD
PMID:21745629 PMID:32347412
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
G
Csf2
colony stimulating factor 2
increases expression multiple interactions affects response to substance
ISO
stearic acid results in increased expression of CSF2 mRNA [CSF2 protein affects the susceptibility to stearic acid] which affects the abundance of Adenosine Triphosphate
CTD
PMID:32347412
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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Cxcr4
C-X-C motif chemokine receptor 4
increases expression
ISO
stearic acid results in increased expression of CXCR4 mRNA
CTD
PMID:32347412
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases activity
ISO
stearic acid results in increased activity of CYP2E1 protein
CTD
PMID:26739624
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
multiple interactions decreases expression
ISO
INS protein inhibits the reaction [stearic acid results in decreased expression of CYP3A4 mRNA] stearic acid results in decreased expression of CYP3A4 mRNA; stearic acid results in decreased expression of CYP3A4 protein
CTD
PMID:26739624
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Dll4
delta like canonical Notch ligand 4
increases expression
ISO
stearic acid results in increased expression of DLL4 mRNA
CTD
PMID:32347412
NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
G
Edn1
endothelin 1
increases expression
ISO
stearic acid results in increased expression of EDN1 mRNA; stearic acid results in increased expression of EDN1 protein
CTD
PMID:16895544
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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Esr1
estrogen receptor 1
multiple interactions
ISO
stearic acid binds to and results in increased activity of ESR1 protein
CTD
PMID:27633901
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Foxo1
forkhead box O1
multiple interactions decreases expression
ISO
resveratrol inhibits the reaction [stearic acid results in decreased expression of FOXO1 protein]
CTD
PMID:17374693
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
G
Gpx1
glutathione peroxidase 1
multiple interactions decreases expression
ISO
resveratrol inhibits the reaction [stearic acid results in decreased expression of GPX1 mRNA]
CTD
PMID:17374693
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Hmox1
heme oxygenase 1
increases expression
ISO
stearic acid results in increased expression of HMOX1 mRNA
CTD
PMID:26739624
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Il6
interleukin 6
multiple interactions increases expression
ISO
resveratrol inhibits the reaction [stearic acid results in increased expression of IL6 mRNA]
CTD
PMID:17374693
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ins2
insulin 2
multiple interactions
ISO
INS protein inhibits the reaction [stearic acid results in decreased expression of CYP3A4 mRNA]; INS protein inhibits the reaction [stearic acid results in increased chemical synthesis of 6-hydroxychlorzoxazone]; INS protein inhibits the reaction [stearic acid results in increased hydroxylation of Chlorzoxazone] [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of stearic acid analog; [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of stearic acid analog
CTD
PMID:26739624 PMID:26820058
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
multiple interactions
ISO
[stearic acid co-treated with Lipopolysaccharides] affects the expression of MAP1LC3B protein
CTD
PMID:33810233
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
G
Mkx
mohawk homeobox
increases expression
ISO
stearic acid results in increased expression of MKX mRNA
CTD
PMID:32347412
NCBI chr17:55,077,073...55,156,877
Ensembl chr17:55,077,540...55,156,124
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Mmp12
matrix metallopeptidase 12
increases expression
ISO
stearic acid results in increased expression of MMP12 mRNA
CTD
PMID:32347412
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
G
Mpo
myeloperoxidase
multiple interactions
ISO
[lupeol binds to stearic acid] inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of MPO protein]
CTD
PMID:32006539
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Ndrg1
N-myc downstream regulated 1
increases expression
ISO
stearic acid results in increased expression of NDRG1 mRNA
CTD
PMID:32347412
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
G
Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression
ISO
stearic acid results in increased expression of NFE2L2 mRNA; stearic acid results in increased expression of NFE2L2 protein
CTD
PMID:28555106
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Pdk4
pyruvate dehydrogenase kinase 4
increases expression
ISO
stearic acid results in increased expression of PDK4 mRNA
CTD
PMID:32347412
NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
G
Pklr
pyruvate kinase L/R
decreases expression
ISO
stearic acid results in decreased expression of PKLR protein
CTD
PMID:26739624
NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
G
Plin1
perilipin 1
increases expression
ISO
stearic acid results in increased expression of PLIN1 mRNA
CTD
PMID:26739624
NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
G
Plin2
perilipin 2
increases expression
ISO
stearic acid results in increased expression of PLIN2 mRNA
CTD
PMID:26739624
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Ppara
peroxisome proliferator activated receptor alpha
multiple interactions
ISO
stearic acid binds to and results in increased activity of PPARA protein
CTD
PMID:10403814
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions
EXP
stearic acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARG protein]
CTD
PMID:17302992
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppargc1a
PPARG coactivator 1 alpha
increases expression
ISO
stearic acid results in increased expression of PPARGC1A mRNA
CTD
PMID:23056435
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
G
Scd
stearoyl-CoA desaturase
multiple interactions decreases response to substance increases expression
EXP
SCD1 protein inhibits the reaction [stearic acid results in increased abundance of Ceramides]; SCD1 protein inhibits the reaction [stearic acid results in increased abundance of Reactive Oxygen Species]; SCD1 protein inhibits the reaction [stearic acid results in increased activity of CASP3 protein] SCD1 protein results in decreased susceptibility to stearic acid stearic acid results in increased expression of SCD1 mRNA
CTD
PMID:22413010
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Serpine1
serpin family E member 1
multiple interactions increases expression
ISO
resveratrol inhibits the reaction [stearic acid results in increased expression of SERPINE1 mRNA]
CTD
PMID:17374693
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Sh3bgr
SH3 domain binding glutamate-rich protein
increases expression
ISO
stearic acid results in increased expression of SH3BGR mRNA
CTD
PMID:32347412
NCBI chr11:35,503,663...35,527,853
Ensembl chr11:35,503,725...35,527,853
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Sirt2
sirtuin 2
multiple interactions
ISO
[stearic acid co-treated with Lipopolysaccharides] affects the expression of SIRT2 protein
CTD
PMID:33810233
NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
G
Sod1
superoxide dismutase 1
increases activity
EXP
stearic acid results in increased activity of SOD1 protein
CTD
PMID:17302992
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Sod2
superoxide dismutase 2
multiple interactions decreases expression
ISO
resveratrol inhibits the reaction [stearic acid results in decreased expression of SOD2 mRNA]
CTD
PMID:17374693
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Sqstm1
sequestosome 1
multiple interactions
ISO
[stearic acid co-treated with Lipopolysaccharides] results in increased expression of SQSTM1 protein
CTD
PMID:33810233
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Tnf
tumor necrosis factor
multiple interactions
ISO
stearic acid promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD
PMID:33810233
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Trib3
tribbles pseudokinase 3
increases expression
ISO
stearic acid results in increased expression of TRIB3 mRNA
CTD
PMID:26739624
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
G
Tuba1b
tubulin, alpha 1B
multiple interactions
ISO
[stearic acid co-treated with Lipopolysaccharides] affects the acylation of TUBA1B protein
CTD
PMID:33810233
NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186
G
Vnn3
vanin 3
increases expression
ISO
stearic acid results in increased expression of VNN3P mRNA
CTD
PMID:32347412
NCBI chr 1:21,571,364...21,583,626
Ensembl chr 1:21,571,364...21,583,626
G
Aifm1
apoptosis inducing factor, mitochondria associated 1
multiple interactions
ISO
[perifosine co-treated with Butyrates] results in increased secretion of AIFM1 protein; [perifosine co-treated with trichostatin A] results in increased secretion of AIFM1 protein; [perifosine co-treated with vorinostat] results in increased secretion of AIFM1 protein
CTD
PMID:15781658
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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Akt1
AKT serine/threonine kinase 1
multiple interactions decreases phosphorylation
ISO
[perifosine co-treated with Butyrates] results in decreased activity of AKT1 protein; [perifosine co-treated with trichostatin A] results in decreased activity of AKT1 protein; [perifosine co-treated with Vorinostat] results in decreased activity of AKT1 protein; AKT1 protein modified form results in decreased activity of [perifosine co-treated with Butyrates]; AKT1 protein modified form results in decreased activity of [perifosine co-treated with trichostatin A]; AKT1 protein modified form results in decreased activity of [perifosine co-treated with Vorinostat]; perifosine inhibits the reaction [cyadox results in increased phosphorylation of AKT1 protein] [perifosine co-treated with temsirolimus] results in decreased activity of AKT1 protein perifosine results in decreased phosphorylation of AKT1 protein
CTD
PMID:15781658 PMID:21267448 PMID:30265530 PMID:31445927
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
G
Bak1
BCL2-antagonist/killer 1
multiple interactions
ISO
[perifosine co-treated with Butyrates] results in decreased expression of BAK1 protein; [perifosine co-treated with trichostatin A] results in decreased expression of BAK1 protein; [perifosine co-treated with vorinostat] results in decreased expression of BAK1 protein
CTD
PMID:15781658
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
G
Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
[perifosine co-treated with Butyrates] results in increased activity of BAX protein; [perifosine co-treated with trichostatin A] results in increased activity of BAX protein; [perifosine co-treated with vorinostat] results in increased activity of BAX protein
CTD
PMID:15781658
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Casp3
caspase 3
multiple interactions decreases expression
ISO
[perifosine co-treated with Butyrates] results in increased activity of CASP3 protein; [perifosine co-treated with trichostatin A] results in increased activity of CASP3 protein; [perifosine co-treated with vorinostat] results in increased activity of CASP3 protein perifosine results in decreased expression of CASP3 protein
CTD
PMID:15781658 PMID:25416439
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
multiple interactions increases expression
ISO
[perifosine co-treated with Butyrates] results in increased activity of CASP8 protein; [perifosine co-treated with trichostatin A] results in increased activity of CASP8 protein; [perifosine co-treated with Vorinostat] results in increased activity of CASP8 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [perifosine results in increased expression of CASP8 protein modified form]; LAT2 protein inhibits the reaction [perifosine results in increased expression of CASP8 protein modified form]
CTD
PMID:15781658 PMID:32587277
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions
ISO
perifosine inhibits the reaction [Mitomycin results in increased expression of CDKN1A protein]
CTD
PMID:34624459
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cycs
cytochrome c, somatic
multiple interactions
ISO
[perifosine co-treated with Butyrates] affects the localization of CYCS protein; [perifosine co-treated with trichostatin A] affects the localization of CYCS protein; [perifosine co-treated with vorinostat] affects the localization of CYCS protein
CTD
PMID:15781658
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
G
Egf
epidermal growth factor
multiple interactions
ISO
perifosine inhibits the reaction [cyadox results in increased expression of EGF]; perifosine inhibits the reaction [Hydrogen Peroxide results in increased expression of EGF]
CTD
PMID:30265530
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
G
Fas
Fas cell surface death receptor
affects response to substance
ISO
perifosine affects the susceptibility to FAS protein
CTD
PMID:31445927
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
G
Foxo1
forkhead box O1
multiple interactions
ISO
[perifosine co-treated with cyadox] results in increased expression of FOXO1 mRNA; [perifosine co-treated with Hydrogen Peroxide] results in increased expression of FOXO1 mRNA perifosine inhibits the reaction [cyanoginosin LR results in increased phosphorylation of FOXO1 protein]
CTD
PMID:30265530 PMID:33078829
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
G
Glb1
galactosidase, beta 1
multiple interactions
ISO
perifosine inhibits the reaction [Mitomycin results in increased activity of GLB1 protein]
CTD
PMID:34624459
NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
G
Lat2
linker for activation of T cells family, member 2
multiple interactions decreases response to substance decreases expression
ISO
ixazomib inhibits the reaction [perifosine results in decreased expression of LAT2 protein]; LAT2 protein inhibits the reaction [perifosine results in increased cleavage of PARP1 protein]; LAT2 protein inhibits the reaction [perifosine results in increased expression of CASP8 protein modified form] LAT2 protein results in decreased susceptibility to perifosine
CTD
PMID:23001822 PMID:32587277
NCBI chr12:22,104,173...22,118,294
Ensembl chr12:22,104,219...22,118,288
G
Map2k1
mitogen activated protein kinase kinase 1
multiple interactions
ISO
MAP2K1 protein mutant form results in decreased activity of [perifosine co-treated with Butyrates]; MAP2K1 protein mutant form results in decreased activity of [perifosine co-treated with trichostatin A]; MAP2K1 protein mutant form results in decreased activity of [perifosine co-treated with vorinostat]
CTD
PMID:15781658
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
[perifosine co-treated with Butyrates] results in decreased activity of MAPK1 protein; [perifosine co-treated with trichostatin A] results in decreased activity of MAPK1 protein; [perifosine co-treated with vorinostat] results in decreased activity of MAPK1 protein
CTD
PMID:15781658
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
[perifosine co-treated with Butyrates] results in decreased activity of MAPK3 protein; [perifosine co-treated with trichostatin A] results in decreased activity of MAPK3 protein; [perifosine co-treated with vorinostat] results in decreased activity of MAPK3 protein
CTD
PMID:15781658
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
[perifosine co-treated with Butyrates] results in increased activity of MAPK8 protein; [perifosine co-treated with trichostatin A] results in increased activity of MAPK8 protein; [perifosine co-treated with vorinostat] results in increased activity of MAPK8 protein
CTD
PMID:15781658
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
G
Mtor
mechanistic target of rapamycin kinase
multiple interactions
ISO
[perifosine co-treated with temsirolimus] results in decreased activity of MTOR protein
CTD
PMID:21267448
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions increases cleavage
ISO
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [perifosine results in increased cleavage of PARP1 protein]; LAT2 protein inhibits the reaction [perifosine results in increased cleavage of PARP1 protein]
CTD
PMID:32587277
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
G
Tnf
tumor necrosis factor
increases response to substance
ISO
perifosine results in increased susceptibility to TNF protein
CTD
PMID:31445927
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tp53
tumor protein p53
multiple interactions
ISO
perifosine inhibits the reaction [cyadox results in increased expression of TP53 mRNA]; perifosine inhibits the reaction [cyadox results in increased expression of TP53 protein]; perifosine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]
CTD
PMID:30265530
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
G
Abcb11
ATP binding cassette subfamily B member 11
affects expression
EXP
Soybean Oil affects the expression of ABCB11 mRNA
CTD
PMID:15770074
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
G
Abcb1b
ATP-binding cassette, sub-family B member 1B
affects expression
EXP
Soybean Oil affects the expression of ABCB1B mRNA
CTD
PMID:15770074
NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
G
Abcb4
ATP binding cassette subfamily B member 4
affects expression
EXP
Soybean Oil affects the expression of ABCB4 mRNA
CTD
PMID:15770074
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
G
Abcc1
ATP binding cassette subfamily C member 1
affects expression
EXP
Soybean Oil affects the expression of ABCC1 mRNA
CTD
PMID:15770074
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
G
Abcc2
ATP binding cassette subfamily C member 2
affects expression
EXP
Soybean Oil affects the expression of ABCC2 mRNA
CTD
PMID:15770074
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Abcc5
ATP binding cassette subfamily C member 5
affects expression
EXP
Soybean Oil affects the expression of ABCC5 mRNA
CTD
PMID:15770074
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
G
Abcc6
ATP binding cassette subfamily C member 6
affects expression
EXP
Soybean Oil affects the expression of ABCC6 mRNA
CTD
PMID:15770074
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
G
Acat1
acetyl-CoA acetyltransferase 1
decreases activity
EXP
Soybean Oil results in decreased activity of ACAT1 protein
CTD
PMID:12559476
NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
G
Bcl2
BCL2, apoptosis regulator
increases expression
EXP
Soybean Oil results in increased expression of BCL2 protein
CTD
PMID:15309441
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Cat
catalase
increases activity
EXP
Soybean Oil results in increased activity of CAT protein
CTD
PMID:12781854
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Ccnd1
cyclin D1
increases expression
EXP
Soybean Oil results in increased expression of CCND1 mRNA
CTD
PMID:21088903
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
G
Cyp4a1
cytochrome P450, family 4, subfamily a, polypeptide 1
affects expression
EXP
Soybean Oil affects the expression of CYP4A1 mRNA
CTD
PMID:16079505
NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases activity
EXP
Soybean Oil results in increased activity of CYP7A1 protein
CTD
PMID:12559476
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Gstp1
glutathione S-transferase pi 1
multiple interactions
EXP
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein]
CTD
PMID:11600134
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases activity
EXP
Soybean Oil results in increased activity of HMGCR protein
CTD
PMID:12559476
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Il12b
interleukin 12B
decreases expression
ISO
Soybean Oil results in decreased expression of IL12B mRNA
CTD
PMID:10065739
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
G
Slc22a1
solute carrier family 22 member 1
affects expression
EXP
Soybean Oil affects the expression of SLC22A1 mRNA
CTD
PMID:15770074
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
G
Slc22a7
solute carrier family 22 member 7
affects expression
EXP
Soybean Oil affects the expression of SLC22A7 mRNA
CTD
PMID:15770074
NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
G
Gsta1
glutathione S-transferase alpha 1
multiple interactions
ISO
stearoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein
CTD
PMID:10542059
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
G
Ppara
peroxisome proliferator activated receptor alpha
multiple interactions
ISO
stearoyl-coenzyme A binds to and results in increased activity of PPARA protein
CTD
PMID:11139385
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions
ISO
stearoyl-coenzyme A binds to and results in increased activity of PPARG protein
CTD
PMID:11139385
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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