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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cetylpyridinium
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Accession:CHEBI:32914 term browser browse the term
Definition:A pyridinium ion that has formula C21H38N.
Synonyms:exact_synonym: 1-hexadecylpyridinium
 related_synonym: Formula=C21H38N;   InChI=1S/C21H38N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-22-20-17-15-18-21-22/h15,17-18,20-21H,2-14,16,19H2,1H3/q+1;   InChIKey=NEUSVAOJNUQRTM-UHFFFAOYSA-N;   N-hexadecylpyridinium;   SMILES=CCCCCCCCCCCCCCCC[n+]1ccccc1
 xref: Beilstein:1431415;   CAS:7773-52-6;   Drug_Central:3083;   Gmelin:342398
 xref_mesh: MESH:D002594



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cetylpyridinium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Cetylpyridinium results in increased cleavage of CASP3 protein] CTD PMID:31982400 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdc6 cell division cycle 6 decreases expression
multiple interactions
ISO Cetylpyridinium results in decreased expression of CDC6 mRNA; Cetylpyridinium results in decreased expression of CDC6 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Cetylpyridinium results in decreased expression of CDC6 protein]
CTD PMID:36725023 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Cetylpyridinium results in increased expression of HMOX1 mRNA CTD PMID:37149095 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Cetylpyridinium results in increased expression of IL1A protein CTD PMID:25290854 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Triclosan co-treated with Cetylpyridinium] inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; [Triclosan co-treated with Cetylpyridinium] inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone] CTD PMID:16253096 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Cetylpyridinium results in increased expression of LDLR mRNA CTD PMID:37149095 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G LOC120094873 U6 spliceosomal RNA increases expression ISO Cetylpyridinium results in increased expression of RNU6-334P CTD PMID:37149095 NCBI chr 9:13,809,929...13,810,029
Ensembl chr 9:13,809,929...13,810,029
Ensembl chr 9:13,809,929...13,810,029
JBrowse link
G Mir125b1 microRNA 125b-1 increases expression ISO Cetylpyridinium results in increased expression of MIR125B1 CTD PMID:37149095 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Cetylpyridinium results in increased activity of NR1I2 protein CTD PMID:28728110 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Cetylpyridinium results in increased cleavage of PARP1 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Cetylpyridinium results in increased cleavage of PARP1 protein]
CTD PMID:31982400 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Triclosan co-treated with Cetylpyridinium] inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; [Triclosan co-treated with Cetylpyridinium] inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA] CTD PMID:16253096 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Triclosan co-treated with Cetylpyridinium] results in decreased phosphorylation of RELA protein CTD PMID:16253096 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Cetylpyridinium results in increased expression of SLC7A11 mRNA CTD PMID:37149095 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Triclosan co-treated with Cetylpyridinium] inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; [Triclosan co-treated with Cetylpyridinium] inhibits the reaction [TNF protein results in increased secretion of Dinoprostone] CTD PMID:16253096 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      molecular entity 19878
        ion 17081
          organic ion 11443
            organic cation 8954
              pyridinium ion 2442
                cetylpyridinium 14
                  cetylpyridinium chloride + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    main group molecular entity 19817
                      p-block molecular entity 19817
                        carbon group molecular entity 19757
                          organic molecular entity 19754
                            organic ion 11443
                              organic cation 8954
                                pyridinium ion 2442
                                  cetylpyridinium 14
                                    cetylpyridinium chloride + 0
paths to the root