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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:secondary amine
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Accession:CHEBI:32863 term browser browse the term
Definition:A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups.
Synonyms:exact_synonym: secondary amines
 related_synonym: Formula=HNR2;   R2NH;   SMILES=[H]N([*])[*];   sekundaeres Amin
 alt_id: CHEBI:26618;   CHEBI:9078
 xref: KEGG:C02324
 cyclic_relationship: is_conjugate_base_of CHEBI:137419


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bisoprolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A increases transport
multiple interactions
ISO ABCB1 protein results in increased transport of Bisoprolol
Bisoprolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; valspodar inhibits the reaction [ABCB1 protein results in increased transport of Bisoprolol]
CTD PMID:16671962 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Adrb1 adrenergic receptor, beta 1 decreases activity
increases expression
multiple interactions
affects binding
ISO Bisoprolol results in decreased activity of ADRB1 protein
Bisoprolol results in increased expression of ADRB1 mRNA
[Bisoprolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; Bisoprolol binds to and results in decreased activity of ADRB1 protein; Bisoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Bisoprolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB1 protein]
Bisoprolol binds to ADRB1 protein
CTD PMID:1389726 PMID:2897299 PMID:10372227 PMID:11562432 PMID:12535855 PMID:14730417 PMID:15060759 PMID:17200720 PMID:20668454 NCBI chr19:56,722,117...56,725,150
Ensembl chr19:56,722,199...56,733,113
JBrowse link
G Adrb2 adrenergic receptor, beta 2 multiple interactions
increases expression
ISO [Bisoprolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Bisoprolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; Bisoprolol binds to and results in decreased activity of ADRB2 protein; Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB2 protein]
Bisoprolol results in increased expression of ADRB2 mRNA
CTD PMID:14730417 PMID:17925438 PMID:20668454 NCBI chr18:62,177,713...62,179,981
Ensembl chr18:62,177,816...62,179,959
JBrowse link
G Adrb3 adrenergic receptor, beta 3 multiple interactions ISO Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB3 protein] CTD PMID:14730417 NCBI chr 8:27,225,776...27,230,845
Ensembl chr 8:27,225,776...27,250,616
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 decreases expression ISO Bisoprolol results in decreased expression of CCL2 protein CTD PMID:19840533 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus increases expression ISO Bisoprolol results in increased expression of GNAS mRNA CTD PMID:20668454 NCBI chr 2:174,284,320...174,346,744
Ensembl chr 2:174,284,320...174,346,744
JBrowse link
G Il10 interleukin 10 increases expression ISO Bisoprolol results in increased expression of IL10 protein CTD PMID:19840533 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Bisoprolol results in decreased expression of IL1B protein CTD PMID:19840533 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 decreases expression ISO Bisoprolol results in decreased expression of IL6 protein CTD PMID:19840533 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Ins2 insulin II multiple interactions ISO Bisoprolol inhibits the reaction [Terbutaline results in increased expression of INS protein] CTD PMID:12795776 NCBI chr 7:142,678,656...142,679,726
Ensembl chr 7:142,678,656...142,743,381
JBrowse link
G Prkca protein kinase C, alpha decreases expression ISO Bisoprolol results in decreased expression of PRKCA protein CTD PMID:20668454 NCBI chr11:107,933,387...108,343,888
Ensembl chr11:107,933,387...108,343,928
JBrowse link
G Prkcd protein kinase C, delta decreases expression ISO Bisoprolol results in decreased expression of PRKCD protein CTD PMID:20668454 NCBI chr14:30,595,353...30,626,414
Ensembl chr14:30,595,354...30,626,210
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 multiple interactions ISO Bisoprolol inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr17:12,648,874...12,675,838
Ensembl chr17:12,648,869...12,675,829
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Bisoprolol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:19740083 NCBI chr17:12,584,189...12,628,489
Ensembl chr17:12,584,132...12,628,488
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Bisoprolol results in decreased expression of TNF protein CTD PMID:19840533 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
brimonidine tartrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenergic receptor, alpha 2a multiple interactions ISO
EXP
Brimonidine Tartrate inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]; Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]; Prazosin inhibits the reaction [Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]]; Yohimbine inhibits the reaction [Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]] CTD PMID:8397342 PMID:10742289 PMID:12208771 PMID:12598592 NCBI chr19:54,045,259...54,048,982
Ensembl chr19:54,044,151...54,048,982
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) multiple interactions ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator multiple interactions EXP Brimonidine Tartrate inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation ISO Brimonidine Tartrate results in increased phosphorylation of CREB1 protein CTD PMID:17680988 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Prkca protein kinase C, alpha affects localization
multiple interactions
ISO Brimonidine Tartrate affects the localization of PRKCA protein
Nitric Oxide deficiency promotes the reaction [Brimonidine Tartrate affects the localization of PRKCA protein]
CTD PMID:12388232 NCBI chr11:107,933,387...108,343,888
Ensembl chr11:107,933,387...108,343,928
JBrowse link
G Prkcd protein kinase C, delta affects localization
multiple interactions
ISO Brimonidine Tartrate affects the localization of PRKCD protein
Nitric Oxide deficiency inhibits the reaction [Brimonidine Tartrate affects the localization of PRKCD protein]
CTD PMID:12388232 NCBI chr14:30,595,353...30,626,414
Ensembl chr14:30,595,354...30,626,210
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Brimonidine Tartrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,584,189...12,628,489
Ensembl chr17:12,584,132...12,628,488
JBrowse link
diethylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hrh3 histamine receptor H3 multiple interactions ISO diethylamine binds to and results in decreased activity of HRH3 protein CTD PMID:17169555 NCBI chr 2:180,099,465...180,104,484
Ensembl chr 2:180,099,465...180,104,488
JBrowse link
G Ifng interferon gamma multiple interactions EXP [diethylamine co-treated with Sodium Dodecyl Sulfate] results in increased expression of IFNG protein CTD PMID:12062936 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il18 interleukin 18 increases activity EXP diethylamine results in increased activity of IL18 protein CTD PMID:15840424 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840
JBrowse link
G Il1a interleukin 1 alpha increases activity EXP diethylamine results in increased activity of IL1A protein CTD PMID:15840424 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il4 interleukin 4 multiple interactions EXP [diethylamine co-treated with Sodium Dodecyl Sulfate] results in increased expression of IL4 protein CTD PMID:12062936 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
dimethylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dek DEK proto-oncogene (DNA binding) increases secretion ISO DEK protein results in increased secretion of dimethylamine CTD PMID:28558019 NCBI chr13:47,084,767...47,107,530
Ensembl chr13:47,084,775...47,106,201
JBrowse link
G Hrh3 histamine receptor H3 multiple interactions ISO dimethylamine binds to and results in decreased activity of HRH3 protein CTD PMID:17169555 NCBI chr 2:180,099,465...180,104,484
Ensembl chr 2:180,099,465...180,104,488
JBrowse link
dobutamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 decreases activity ISO Dobutamine results in decreased activity of ABCB11 protein CTD PMID:28437613 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616
JBrowse link
G Adcy6 adenylate cyclase 6 affects response to substance EXP ADCY6 protein affects the susceptibility to Dobutamine CTD PMID:12393090 NCBI chr15:98,589,978...98,610,287
Ensembl chr15:98,589,973...98,610,076
JBrowse link
G Adra2a adrenergic receptor, alpha 2a multiple interactions ISO Dobutamine binds to and results in increased activity of ADRA2A protein CTD PMID:16024912 NCBI chr19:54,045,259...54,048,982
Ensembl chr19:54,044,151...54,048,982
JBrowse link
G Adrb1 adrenergic receptor, beta 1 affects response to substance
multiple interactions
ISO ADRB1 gene affects the susceptibility to Dobutamine; ADRB1 gene polymorphism affects the susceptibility to Dobutamine; ADRB1 protein polymorphism affects the susceptibility to Dobutamine
ADRB1 gene polymorphism affects the susceptibility to [Dobutamine co-treated with Metoprolol]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Dobutamine binds to and results in increased activity of ADRB1 protein; Dobutamine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of and results in increased uptake of EGFR protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]
[Dobutamine co-treated with ICI 118551] results in decreased expression of ADRB1 mRNA; [Dobutamine co-treated with ICI 118551] results in decreased expression of ADRB1 protein; Dobutamine binds to and results in increased activity of ADRB1 protein; Dobutamine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Oxygen deficiency results in increased susceptibility to [Dobutamine binds to and results in increased activity of ADRB1 protein]
CTD PMID:8096834 PMID:10192281 PMID:11753577 PMID:14502278 PMID:15564877 PMID:16024912 PMID:18787115 PMID:19719783 PMID:20821015 PMID:21311897 NCBI chr19:56,722,117...56,725,150
Ensembl chr19:56,722,199...56,733,113
JBrowse link
G Adrb2 adrenergic receptor, beta 2 affects response to substance ISO ADRB2 gene polymorphism affects the susceptibility to Dobutamine CTD PMID:17094270 NCBI chr18:62,177,713...62,179,981
Ensembl chr18:62,177,816...62,179,959
JBrowse link
G Adrb3 adrenergic receptor, beta 3 multiple interactions ISO [Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 mRNA; [Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 protein CTD PMID:19719783 NCBI chr 8:27,225,776...27,230,845
Ensembl chr 8:27,225,776...27,250,616
JBrowse link
G Ahsg alpha-2-HS-glycoprotein affects response to substance EXP AHSG protein affects the susceptibility to Dobutamine CTD PMID:16177000 NCBI chr16:22,892,015...22,899,451
Ensembl chr16:22,891,277...22,899,449
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 affects response to substance
multiple interactions
ISO AKT1 protein affects the susceptibility to Dobutamine
Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein]
CTD PMID:16094411 PMID:16339297 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Akt2 thymoma viral proto-oncogene 2 multiple interactions ISO Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT2 protein] CTD PMID:16339297 NCBI chr 7:27,591,552...27,640,826
Ensembl chr 7:27,591,552...27,640,826
JBrowse link
G Akt3 thymoma viral proto-oncogene 3 multiple interactions ISO Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT3 protein] CTD PMID:16339297 NCBI chr 1:177,020,076...177,261,781
Ensembl chr 1:177,020,073...177,258,203
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]] CTD PMID:18787115 NCBI chr 7:99,535,147...99,606,772
Ensembl chr 7:99,535,466...99,606,771
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]] CTD PMID:18787115 NCBI chr11:70,432,485...70,440,828
Ensembl chr11:70,432,635...70,440,828
JBrowse link
G Bax BCL2-associated X protein increases expression EXP Dobutamine results in increased expression of BAX protein CTD PMID:15052282 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression EXP Dobutamine results in decreased expression of BCL2 protein CTD PMID:15052282 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bnip1 BCL2/adenovirus E1B interacting protein 1 increases expression EXP Dobutamine results in increased expression of BNIP1 protein CTD PMID:15052282 NCBI chr17:26,781,079...26,792,521
Ensembl chr17:26,781,066...26,792,565
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions ISO Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] CTD PMID:12818967 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 multiple interactions ISO Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 protein] CTD PMID:12818968 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355
JBrowse link
G Clu clusterin increases expression EXP Dobutamine results in increased expression of CLU protein CTD PMID:15052282 NCBI chr14:65,968,483...65,981,548
Ensembl chr14:65,968,483...65,981,547
JBrowse link
G Comt catechol-O-methyltransferase increases methylation
increases expression
ISO COMT protein results in increased methylation of Dobutamine
Dobutamine results in increased expression of COMT mRNA
CTD PMID:11160877 PMID:12423672 NCBI chr16:18,406,882...18,426,716
Ensembl chr16:18,406,886...18,426,852
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression ISO Dobutamine results in increased expression of CPT1A mRNA; Dobutamine results in increased expression of CPT1A protein CTD PMID:8479178 NCBI chr19:3,322,326...3,385,735
Ensembl chr19:3,322,334...3,385,733
JBrowse link
G Crem cAMP responsive element modulator affects response to substance EXP CREM protein affects the susceptibility to Dobutamine CTD PMID:12475904 NCBI chr18:3,266,354...3,337,773
Ensembl chr18:3,266,048...3,337,748
JBrowse link
G Ctf1 cardiotrophin 1 affects response to substance EXP CTF1 protein affects the susceptibility to Dobutamine CTD PMID:17150369 NCBI chr 7:127,712,676...127,718,188
Ensembl chr 7:127,712,736...127,718,192
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions
increases expression
ISO Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]; Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 protein]
Dobutamine results in increased expression of CXCL8 mRNA
CTD PMID:12818968 PMID:15502056 PMID:32816093 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 multiple interactions EXP Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA] CTD PMID:11605937 NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938
JBrowse link
G Dbh dopamine beta hydroxylase affects response to substance EXP DBH protein affects the susceptibility to Dobutamine CTD PMID:10338466 NCBI chr 2:27,165,507...27,183,204
Ensembl chr 2:27,165,233...27,183,200
JBrowse link
G Dmd dystrophin, muscular dystrophy increases response to substance EXP DMD gene mutant form results in increased susceptibility to Dobutamine CTD PMID:17440445 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141
JBrowse link
G Egfr epidermal growth factor receptor decreases response to substance
multiple interactions
EXP
ISO
EGFR gene mutant form results in decreased susceptibility to Dobutamine
AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of and results in increased uptake of EGFR protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]
CTD PMID:18599591 PMID:18787115 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO Dobutamine binds to and results in increased activity of ESR1 protein CTD PMID:24928891 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G F3 coagulation factor III increases expression ISO Dobutamine results in increased expression of F3 protein CTD PMID:16286589 NCBI chr 3:121,723,537...121,735,052
Ensembl chr 3:121,723,537...121,735,048
JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance ISO
EXP
FGF2 protein affects the susceptibility to Dobutamine CTD PMID:10491406 PMID:14583313 NCBI chr 3:37,348,477...37,410,106
Ensembl chr 3:37,348,346...37,410,108
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]; Metoprolol inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked increases activity ISO Dobutamine results in increased activity of G6PD protein CTD PMID:1978808 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Gh growth hormone multiple interactions ISO GH1 protein promotes the reaction [Dobutamine results in increased metabolism of Lipids] CTD PMID:14981226 NCBI chr11:106,300,261...106,303,703
Ensembl chr11:106,300,271...106,301,865
JBrowse link
G Gk glycerol kinase increases activity ISO Dobutamine results in increased activity of GK protein CTD PMID:12736183 NCBI chr  X:85,701,937...85,776,819
Ensembl chr  X:85,701,937...85,776,819
JBrowse link
G Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus increases response to substance ISO GNAS gene SNP results in increased susceptibility to Dobutamine CTD PMID:19542315 NCBI chr 2:174,284,320...174,346,744
Ensembl chr 2:174,284,320...174,346,744
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects response to substance EXP GSK3B gene mutant form affects the susceptibility to Dobutamine CTD PMID:17901358 NCBI chr16:38,089,001...38,246,084
Ensembl chr16:38,089,001...38,246,084
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]] CTD PMID:18787115 NCBI chr18:36,504,927...36,515,805
Ensembl chr18:36,504,927...36,515,805
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO esmolol inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]; Metoprolol inhibits the reaction [Dobutamine results in increased expression of HMOX1 mRNA]; Metoprolol inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased expression of HMOX1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]
Dobutamine results in increased expression of HMOX1 mRNA; Dobutamine results in increased expression of HMOX1 protein
CTD PMID:15179140 PMID:16627864 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Igf1 insulin-like growth factor 1 increases response to substance ISO IGF1 protein results in increased susceptibility to Dobutamine CTD PMID:17184500 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]
Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
CTD PMID:11605937 PMID:15502056 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression
ISO Dobutamine results in increased expression of IL1B mRNA
Dobutamine results in decreased expression of IL1B mRNA
CTD PMID:9387890 PMID:32816093 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 increases expression
decreases expression
multiple interactions
ISO
EXP
Dobutamine results in increased expression of IL6 protein
Dobutamine results in decreased expression of IL6 mRNA
Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD PMID:11605937 PMID:12423672 PMID:16286589 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) affects response to substance EXP ITGB1 protein affects the susceptibility to Dobutamine CTD PMID:11884376 NCBI chr 8:128,685,654...128,733,579
Ensembl chr 8:128,685,654...128,733,200
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]; Metoprolol inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Jund jun D proto-oncogene multiple interactions ISO Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]; Metoprolol inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr 8:70,697,739...70,700,616
Ensembl chr 8:70,698,949...70,700,616
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Dobutamine results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 5:24,319,589...24,351,684
Ensembl chr 5:24,319,589...24,351,604
JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 multiple interactions
affects response to substance
EXP KCNJ11 protein affects the reaction [[Manganese co-treated with Dobutamine] results in increased abundance of Calcium]
KCNJ11 protein affects the susceptibility to Dobutamine
CTD PMID:17189350 NCBI chr 7:46,097,123...46,100,952
Ensembl chr 7:46,093,953...46,100,764
JBrowse link
G Klk1 kallikrein 1 affects response to substance ISO KLK1 protein affects the susceptibility to Dobutamine CTD PMID:12411458 NCBI chr 7:44,225,360...44,229,622
Ensembl chr 7:44,225,360...44,229,618
JBrowse link
G Lep leptin decreases secretion
decreases expression
ISO
EXP
Dobutamine results in decreased secretion of LEP protein
Dobutamine results in decreased expression of LEP mRNA; Dobutamine results in decreased expression of LEP protein
CTD PMID:9002984 PMID:11022189 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Lepr leptin receptor affects response to substance EXP LEPR protein affects the susceptibility to Dobutamine CTD PMID:20175764 NCBI chr 4:101,717,137...101,815,352
Ensembl chr 4:101,717,404...101,815,352
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO [Dobutamine co-treated with ICI 118551] results in increased activity of MAPK1 protein
AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]
Dobutamine results in increased phosphorylation of MAPK1 protein
CTD PMID:16760913 PMID:18787115 PMID:19719783 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [Dobutamine co-treated with ICI 118551] results in increased activity of MAPK3 protein
AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]
Dobutamine results in increased phosphorylation of MAPK3 protein
CTD PMID:16760913 PMID:18787115 PMID:19719783 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Dobutamine co-treated with ICI 118551] results in increased activity of MAPK9 protein CTD PMID:19719783 NCBI chr11:49,846,728...49,886,421
Ensembl chr11:49,846,751...49,886,421
JBrowse link
G Mb myoglobin affects response to substance EXP MB protein affects the susceptibility to Dobutamine CTD PMID:10468637 NCBI chr15:77,015,487...77,050,668
Ensembl chr15:77,015,487...77,050,670
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] CTD PMID:15502056 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal affects response to substance EXP NOS1 protein affects the susceptibility to Dobutamine CTD PMID:16344403 NCBI chr 5:117,866,839...117,958,840
Ensembl chr 5:117,781,032...117,958,840
JBrowse link
G Nos2 nitric oxide synthase 2, inducible affects response to substance ISO
EXP
NOS2 protein affects the susceptibility to Dobutamine CTD PMID:9396439 PMID:11489778 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases activity ISO Dobutamine results in increased activity of NR1H4 protein CTD PMID:22414727 NCBI chr10:89,454,234...89,533,645
Ensembl chr10:89,454,234...89,533,585
JBrowse link
G Phgdh 3-phosphoglycerate dehydrogenase increases expression ISO Dobutamine results in increased expression of PHGDH mRNA CTD PMID:12423672 NCBI chr 3:98,313,171...98,339,969
Ensembl chr 3:98,313,170...98,339,990
JBrowse link
G Pln phospholamban affects response to substance ISO PLN protein affects the susceptibility to Dobutamine CTD PMID:14991071 NCBI chr10:53,337,686...53,345,999
Ensembl chr10:53,337,667...53,345,987
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform affects response to substance EXP PPP2CA protein affects the susceptibility to Dobutamine CTD PMID:15247211 NCBI chr11:52,098,824...52,122,749
Ensembl chr11:52,098,681...52,127,778
JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha multiple interactions ISO Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of PRKACA protein] CTD PMID:16339297 NCBI chr 8:83,972,978...83,996,444
Ensembl chr 8:83,972,993...83,996,443
JBrowse link
G Prkce protein kinase C, epsilon affects response to substance EXP PRKCE protein affects the susceptibility to Dobutamine CTD PMID:15242976 NCBI chr17:86,167,785...86,657,919
Ensembl chr17:86,167,785...86,657,919
JBrowse link
G Prop1 paired like homeodomain factor 1 decreases response to substance EXP PROP1 gene mutant form results in decreased susceptibility to Dobutamine CTD PMID:19414510 NCBI chr11:50,950,806...50,953,757
Ensembl chr11:50,950,806...50,953,765
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Dobutamine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ren1 renin 1 structural multiple interactions
increases expression
increases secretion
increases activity
ISO Cycloheximide inhibits the reaction [Dobutamine results in increased secretion of REN protein]; Dactinomycin inhibits the reaction [Dobutamine results in increased secretion of REN protein]
Dobutamine results in increased expression of REN mRNA
Dobutamine results in increased activity of REN protein
CTD PMID:9203624 PMID:9209250 NCBI chr 1:133,350,674...133,360,320
Ensembl chr 1:133,350,510...133,360,325
JBrowse link
G S100a1 S100 calcium binding protein A1 increases response to substance EXP S100A1 gene mutant form results in increased susceptibility to Dobutamine CTD PMID:18645228 NCBI chr 3:90,511,034...90,514,330
Ensembl chr 3:90,511,034...90,514,392
JBrowse link
G Scnn1g sodium channel, nonvoltage-gated 1 gamma increases expression ISO Dobutamine results in increased expression of SCNN1G mRNA CTD PMID:16638327 NCBI chr 7:121,734,420...121,768,482
Ensembl chr 7:121,734,479...121,768,475
JBrowse link
G Sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) affects response to substance EXP SGCD affects the susceptibility to Dobutamine CTD PMID:20675662 NCBI chr11:46,971,077...47,989,451
Ensembl chr11:46,896,253...47,988,969
JBrowse link
G Sptan1 spectrin alpha, non-erythrocytic 1 increases degradation ISO Dobutamine deficiency results in increased degradation of SPTAN1 protein CTD PMID:15849228 NCBI chr 2:29,965,560...30,031,451
Ensembl chr 2:29,965,560...30,031,451
JBrowse link
G Tac1 tachykinin 1 multiple interactions ISO Dobutamine promotes the reaction [TAC1 protein binds to and results in increased activity of TACR1 protein] CTD PMID:8994422 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions ISO Dobutamine promotes the reaction [TAC1 protein binds to and results in increased activity of TACR1 protein] CTD PMID:8994422 NCBI chr 6:82,402,003...82,560,104
Ensembl chr 6:82,402,334...82,560,104
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Dobutamine results in increased expression of TGFB1 mRNA CTD PMID:16760913 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO Dobutamine results in increased expression of TGFB2 mRNA CTD PMID:16760913 NCBI chr 1:186,622,787...186,709,697
Ensembl chr 1:186,622,792...186,705,989
JBrowse link
G Tnf tumor necrosis factor decreases expression
decreases secretion
ISO Dobutamine results in decreased expression of TNF mRNA
Dobutamine results in decreased secretion of TNF protein
CTD PMID:12423672 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 decreases expression ISO Dobutamine results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 2:52,038,113...52,056,681
Ensembl chr 2:52,038,009...52,056,686
JBrowse link
G Usf1 upstream transcription factor 1 multiple interactions ISO USF1 gene polymorphism promotes the reaction [Dobutamine results in increased metabolism of Lipids]; USF1 protein affects the reaction [Dobutamine results in increased metabolism of Lipids] CTD PMID:15985485 NCBI chr 1:171,411,307...171,418,954
Ensembl chr 1:171,411,313...171,419,142
JBrowse link
G Vegfa vascular endothelial growth factor A affects response to substance ISO
EXP
VEGFA protein affects the susceptibility to Dobutamine CTD PMID:11599061 PMID:14583313 PMID:19237429 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
maleimide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trp53 transformation related protein 53 multiple interactions ISO maleimide analog binds to and results in increased activity of TP53 protein mutant form CTD PMID:15998635 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
methamphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 2610528J11Rik RIKEN cDNA 2610528J11 gene multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RGD1305347 mRNA
Methamphetamine results in decreased expression of RGD1305347 mRNA
CTD PMID:19564919 NCBI chr 4:118,526,962...118,530,217
Ensembl chr 4:118,526,999...118,530,228
JBrowse link
G 4921524J17Rik RIKEN cDNA 4921524J17 gene increases expression ISO Methamphetamine results in increased expression of RGD1308706 mRNA CTD PMID:19564919 NCBI chr 8:85,408,759...85,432,841
Ensembl chr 8:85,408,759...85,432,833
JBrowse link
G 9930012K11Rik RIKEN cDNA 9930012K11 gene decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of RGD1308117 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RGD1308117 mRNA
CTD PMID:19564919 NCBI chr14:70,154,405...70,159,502
Ensembl chr14:70,154,405...70,159,502
JBrowse link
G Aanat arylalkylamine N-acetyltransferase decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of AANAT mRNA
Lithium inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]
CTD PMID:19149911 NCBI chr11:116,591,721...116,597,680
Ensembl chr11:116,586,432...116,597,680
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A multiple interactions
decreases expression
ISO Melatonin inhibits the reaction [Methamphetamine results in decreased expression of ABCB1 protein] CTD PMID:28223141 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of ABCC6 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCC6 mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr 7:45,974,110...46,030,491
Ensembl chr 7:45,967,555...46,030,302
JBrowse link
G Abcd3 ATP-binding cassette, sub-family D (ALD), member 3 increases expression EXP Methamphetamine results in increased expression of ABCD3 mRNA CTD PMID:26307267 NCBI chr 3:121,758,904...121,815,302
Ensembl chr 3:121,758,774...121,815,302
JBrowse link
G Abcd4 ATP-binding cassette, sub-family D (ALD), member 4 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of ABCD4 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCD4 mRNA
CTD PMID:19564919 NCBI chr12:84,601,869...84,617,485
Ensembl chr12:84,601,464...84,617,413
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCG2 mRNA
Methamphetamine results in decreased expression of ABCG2 mRNA
CTD PMID:19564919 NCBI chr 6:58,584,491...58,692,451
Ensembl chr 6:58,584,523...58,695,676
JBrowse link
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase increases expression EXP Methamphetamine results in increased expression of ABL1 mRNA CTD PMID:26307267 NCBI chr 2:31,688,244...31,807,093
Ensembl chr 2:31,688,376...31,804,227
JBrowse link
G Ablim1 actin-binding LIM protein 1 increases expression EXP
ISO
Methamphetamine results in increased expression of ABLIM1 mRNA CTD PMID:26307267 PMID:32035215 NCBI chr19:57,032,733...57,315,344
Ensembl chr19:57,032,733...57,314,919
JBrowse link
G Abra actin-binding Rho activating protein multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] affects the expression of ABRA mRNA
Methamphetamine results in increased expression of ABRA mRNA
CTD PMID:19564919 NCBI chr15:41,865,293...41,869,720
Ensembl chr15:41,864,076...41,869,720
JBrowse link
G Acacb acetyl-Coenzyme A carboxylase beta increases expression EXP Methamphetamine results in increased expression of ACACB mRNA CTD PMID:26307267 NCBI chr 5:114,146,321...114,250,761
Ensembl chr 5:114,146,535...114,250,761
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 increases expression EXP Methamphetamine results in increased expression of ACIN1 mRNA CTD PMID:26307267 NCBI chr14:54,642,161...54,686,965
Ensembl chr14:54,642,161...54,686,931
JBrowse link
G Aco1 aconitase 1 increases expression ISO Methamphetamine results in increased expression of ACO1 protein CTD PMID:19826936 NCBI chr 4:40,143,265...40,199,009
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Aco2 aconitase 2, mitochondrial increases expression ISO Methamphetamine results in increased expression of ACO2 protein CTD PMID:19826936 NCBI chr15:81,872,463...81,915,137
Ensembl chr15:81,872,309...81,915,133
JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of ACOT1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ACOT1 mRNA
CTD PMID:19564919 NCBI chr12:84,009,502...84,017,670
Ensembl chr12:84,009,490...84,018,371
JBrowse link
G Acox3 acyl-Coenzyme A oxidase 3, pristanoyl increases expression ISO Methamphetamine results in increased expression of ACOX3 mRNA CTD PMID:15644446 NCBI chr 5:35,582,981...35,614,208
Ensembl chr 5:35,583,040...35,615,352
JBrowse link
G Acrbp proacrosin binding protein increases expression EXP Methamphetamine results in increased expression of ACRBP mRNA CTD PMID:26307267 NCBI chr 6:125,049,927...125,063,265
Ensembl chr 6:125,049,689...125,063,267
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of ACSL5 mRNA
Lithium inhibits the reaction [Methamphetamine results in increased expression of ACSL5 mRNA]
CTD PMID:19149911 NCBI chr19:55,251,861...55,296,628
Ensembl chr19:55,251,938...55,297,720
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 affects response to substance ISO ACSL6 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr11:54,303,805...54,364,756
Ensembl chr11:54,303,798...54,364,756
JBrowse link
G Actb actin, beta decreases expression ISO Methamphetamine results in decreased expression of ACTB protein CTD PMID:19826936 NCBI chr 5:142,903,115...142,907,976
Ensembl chr 5:142,903,115...142,906,754
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression ISO Methamphetamine results in decreased expression of ACTC1 mRNA CTD PMID:25290377 NCBI chr 2:114,047,282...114,052,875
Ensembl chr 2:114,047,282...114,053,548
JBrowse link
G Actg1 actin, gamma, cytoplasmic 1 decreases expression ISO Methamphetamine results in decreased expression of ACTG1 protein CTD PMID:19826936 NCBI chr11:120,345,687...120,348,495
Ensembl chr11:120,345,690...120,348,542
JBrowse link
G Acvrl1 activin A receptor, type II-like 1 decreases methylation EXP Methamphetamine results in decreased methylation of ACVRL1 promoter CTD PMID:26307267 NCBI chr15:101,128,522...101,145,336
Ensembl chr15:101,128,522...101,145,336
JBrowse link
G Adam15 a disintegrin and metallopeptidase domain 15 (metargidin) increases expression EXP Methamphetamine results in increased expression of ADAM15 mRNA CTD PMID:26307267 NCBI chr 3:89,339,640...89,350,028
Ensembl chr 3:89,338,542...89,349,996
JBrowse link
G Adam4 a disintegrin and metallopeptidase domain 4 increases expression EXP Methamphetamine results in increased expression of ADAM4 mRNA CTD PMID:26307267 NCBI chr12:81,419,443...81,422,039
Ensembl chr12:81,419,443...81,421,946
JBrowse link
G Adamts9 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 multiple interactions
increases expression
ISO
EXP
[Methamphetamine co-treated with SCH 23390] results in increased expression of ADAMTS9 mRNA
Methamphetamine results in increased expression of ADAMTS9 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr 6:92,772,699...92,944,450
Ensembl chr 6:92,772,699...92,943,492
JBrowse link
G Adamtsl5 ADAMTS-like 5 increases expression EXP Methamphetamine results in increased expression of ADAMTSL5 mRNA CTD PMID:26307267 NCBI chr10:80,339,793...80,349,030
Ensembl chr10:80,339,110...80,348,412
JBrowse link
G Adck2 aarF domain containing kinase 2 decreases expression ISO Methamphetamine results in decreased expression of ADCK2 mRNA CTD PMID:19564919 NCBI chr 6:39,573,844...39,588,769
Ensembl chr 6:39,573,873...39,588,769
JBrowse link
G Adck5 aarF domain containing kinase 5 decreases expression ISO Methamphetamine results in decreased expression of ADCK5 mRNA CTD PMID:19564919 NCBI chr15:76,576,359...76,595,812
Ensembl chr15:76,576,358...76,595,816
JBrowse link
G Adcy3 adenylate cyclase 3 multiple interactions
decreases expression
EXP (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of ADCY3 mRNA] CTD PMID:11756511 NCBI chr12:4,133,116...4,213,525
Ensembl chr12:4,133,103...4,213,525
JBrowse link
G Adcy4 adenylate cyclase 4 increases expression EXP Methamphetamine results in increased expression of ADCY4 mRNA CTD PMID:26307267 NCBI chr14:55,769,056...55,784,095
Ensembl chr14:55,769,057...55,784,095
JBrowse link
G Adcy6 adenylate cyclase 6 increases expression EXP Methamphetamine results in increased expression of ADCY6 mRNA CTD PMID:26307267 NCBI chr15:98,589,978...98,610,287
Ensembl chr15:98,589,973...98,610,076
JBrowse link
G Add2 adducin 2 (beta) increases expression ISO Methamphetamine results in increased expression of ADD2 mRNA CTD PMID:19564919 NCBI chr 6:86,028,681...86,124,409
Ensembl chr 6:86,028,681...86,124,409
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 increases expression EXP Methamphetamine results in increased expression of ADGRF5 mRNA CTD PMID:26307267 NCBI chr17:43,360,329...43,459,557
Ensembl chr17:43,360,451...43,459,557
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression EXP Methamphetamine results in decreased expression of ADIPOQ mRNA CTD PMID:26307267 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Adora1 adenosine A1 receptor multiple interactions EXP
ISO
[8-cyclopentyl-1,3-dimethylxanthine binds to and results in decreased activity of ADORA1 protein] inhibits the reaction [[Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine]; [Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine
[N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] promotes the reaction [Methamphetamine results in increased secretion of Dopamine]; [N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] which results in increased susceptibility to Methamphetamine
CTD PMID:7996441 PMID:11043458 NCBI chr 1:134,199,215...134,235,457
Ensembl chr 1:134,199,223...134,235,431
JBrowse link
G Adora2a adenosine A2a receptor increases response to substance ISO ADORA2A gene SNP results in increased susceptibility to Methamphetamine CTD PMID:20799992 NCBI chr10:75,316,877...75,334,792
Ensembl chr10:75,316,877...75,334,784
JBrowse link
G Adora3 adenosine A3 receptor decreases expression
affects response to substance
ISO
EXP
Methamphetamine results in decreased expression of ADORA3 mRNA
ADORA3 affects the susceptibility to Methamphetamine
CTD PMID:19564919 PMID:21867746 NCBI chr 3:105,904,421...105,908,928
Ensembl chr 3:105,870,858...105,908,926
JBrowse link
G Adpgk ADP-dependent glucokinase decreases expression ISO Methamphetamine results in decreased expression of ADPGK mRNA CTD PMID:19564919 NCBI chr 9:59,291,572...59,316,200
Ensembl chr 9:59,291,558...59,324,052
JBrowse link
G Adra1b adrenergic receptor, alpha 1b affects response to substance EXP ADRA1B protein affects the susceptibility to Methamphetamine CTD PMID:12871582 NCBI chr11:43,774,605...43,901,250
Ensembl chr11:43,774,606...43,901,210
JBrowse link
G Agbl5 ATP/GTP binding protein-like 5 increases expression EXP Methamphetamine results in increased expression of AGBL5 mRNA CTD PMID:26307267 NCBI chr 5:30,888,639...30,906,666
Ensembl chr 5:30,888,694...30,906,965
JBrowse link
G Agmat agmatine ureohydrolase (agmatinase) decreases expression ISO Methamphetamine results in decreased expression of AGMAT mRNA CTD PMID:19564919 NCBI chr 4:141,746,675...141,759,263
Ensembl chr 4:141,746,672...141,759,263
JBrowse link
G Agrn agrin increases expression EXP Methamphetamine results in increased expression of AGRN mRNA CTD PMID:26307267 NCBI chr 4:156,165,290...156,197,533
Ensembl chr 4:156,165,290...156,197,488
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) increases expression
multiple interactions
ISO Methamphetamine results in increased expression of AGT protein
candesartan cilexetil promotes the reaction [Methamphetamine results in increased expression of AGT protein]
CTD PMID:33421459 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO Methamphetamine results in increased expression of AGTR1A protein CTD PMID:33421459 NCBI chr13:30,336,356...30,382,867
Ensembl chr13:30,336,441...30,382,867
JBrowse link
G Ahnak AHNAK nucleoprotein (desmoyokin) increases expression EXP Methamphetamine results in increased expression of AHNAK mRNA CTD PMID:26307267 NCBI chr19:8,989,284...9,076,935
Ensembl chr19:8,989,284...9,076,914
JBrowse link
G Ahsa2 AHA1, activator of heat shock protein ATPase 2 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of AHSA2 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of AHSA2 mRNA] CTD PMID:19564919 NCBI chr11:23,487,882...23,498,045
Ensembl chr11:23,487,882...23,498,030
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of AIF1 protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; Minocycline inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]
CTD PMID:26283213 PMID:29467000 PMID:32278788 PMID:32916201 NCBI chr17:35,170,986...35,176,083
Ensembl chr17:35,170,991...35,176,068
JBrowse link
G Ajap1 adherens junction associated protein 1 increases expression ISO Methamphetamine results in increased expression of AJAP1 mRNA CTD PMID:25290377 NCBI chr 4:153,373,221...153,483,795
Ensembl chr 4:153,373,221...153,482,811
JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Methamphetamine results in decreased expression of AK1 protein CTD PMID:19826936 NCBI chr 2:32,621,758...32,635,058
Ensembl chr 2:32,621,758...32,635,058
JBrowse link
G Ak5 adenylate kinase 5 affects response to substance ISO AK5 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 3:152,462,815...152,668,406
Ensembl chr 3:152,462,815...152,668,360
JBrowse link
G Akap13 A kinase (PRKA) anchor protein 13 increases expression EXP Methamphetamine results in increased expression of AKAP13 mRNA CTD PMID:26307267 NCBI chr 7:75,455,526...75,754,609
Ensembl chr 7:75,455,534...75,754,609
JBrowse link
G Akap8l A kinase (PRKA) anchor protein 8-like increases expression EXP Methamphetamine results in increased expression of AKAP8L mRNA CTD PMID:26307267 NCBI chr17:32,321,424...32,350,616
Ensembl chr17:32,321,424...32,350,607
JBrowse link
G Akr7a5 aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) decreases methylation EXP Methamphetamine results in decreased methylation of AKR7A5 promoter CTD PMID:26307267 NCBI chr 4:139,310,720...139,318,786
Ensembl chr 4:139,310,744...139,318,426
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases response to substance
increases phosphorylation
multiple interactions
affects phosphorylation
decreases phosphorylation
ISO
EXP
AKT1 gene SNP results in increased susceptibility to Methamphetamine
Methamphetamine results in increased phosphorylation of AKT1 protein
Luteolin inhibits the reaction [Methamphetamine results in increased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein
[Rosiglitazone co-treated with Methamphetamine] results in increased phosphorylation of AKT1 protein
Methamphetamine affects the phosphorylation of AKT1 protein
Methamphetamine results in decreased phosphorylation of AKT1 protein
rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein]
CTD PMID:15982448 PMID:29981415 PMID:30742852 PMID:31270305 PMID:32035215 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 increases expression ISO Methamphetamine results in increased expression of ALDH1A2 mRNA CTD PMID:25290377 NCBI chr 9:71,215,789...71,296,243
Ensembl chr 9:71,215,789...71,296,243
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial decreases expression ISO Methamphetamine results in decreased expression of ALDH2 mRNA CTD PMID:15644446 NCBI chr 5:121,566,027...121,593,824
Ensembl chr 5:121,566,027...121,593,824
JBrowse link
G Aldoc aldolase C, fructose-bisphosphate multiple interactions
increases expression
affects localization
ISO 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the localization of ALDOC mRNA]
Methamphetamine results in increased expression of ALDOC protein
CTD PMID:18299792 PMID:19826936 NCBI chr11:78,323,073...78,327,781
Ensembl chr11:78,322,968...78,327,781
JBrowse link
G Alg1 asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase) multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ALG1 mRNA
Methamphetamine results in decreased expression of ALG1 mRNA
CTD PMID:19564919 NCBI chr16:5,233,621...5,244,909
Ensembl chr16:5,233,621...5,244,912
JBrowse link
G Als2cl ALS2 C-terminal like increases expression EXP Methamphetamine results in increased expression of ALS2CL mRNA CTD PMID:26307267 NCBI chr 9:110,880,120...110,900,530
Ensembl chr 9:110,879,870...110,900,530
JBrowse link
G Amdhd2 amidohydrolase domain containing 2 decreases expression ISO Methamphetamine results in decreased expression of AMDHD2 mRNA CTD PMID:19564919 NCBI chr17:24,155,833...24,163,733
Ensembl chr17:24,155,833...24,163,766
JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 increases expression ISO Methamphetamine results in increased expression of AMPD1 mRNA CTD PMID:19564919 NCBI chr 3:103,073,897...103,099,720
Ensembl chr 3:103,074,014...103,099,720
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 decreases expression ISO Methamphetamine results in decreased expression of AMPD3 mRNA CTD PMID:15644446 NCBI chr 7:110,767,790...110,812,409
Ensembl chr 7:110,768,206...110,812,405
JBrowse link
G Angel1 angel homolog 1 decreases expression ISO Methamphetamine results in decreased expression of ANGEL1 mRNA CTD PMID:19564919 NCBI chr12:86,699,719...86,734,303
Ensembl chr12:86,700,502...86,726,460
JBrowse link
G Angpt2 angiopoietin 2 increases expression ISO Methamphetamine results in increased expression of ANGPT2 mRNA CTD PMID:25290377 NCBI chr 8:18,690,263...18,741,562
Ensembl chr 8:18,690,263...18,741,562
JBrowse link
G Ankrd11 ankyrin repeat domain 11 increases expression EXP Methamphetamine results in increased expression of ANKRD11 mRNA CTD PMID:26307267 NCBI chr 8:122,883,321...123,042,284
Ensembl chr 8:122,883,822...123,042,277
JBrowse link
G Ankrd16 ankyrin repeat domain 16 decreases expression ISO Methamphetamine results in decreased expression of ANKRD16 mRNA CTD PMID:19564919 NCBI chr 2:11,777,753...11,790,327
Ensembl chr 2:11,777,876...11,790,329
JBrowse link
G Ankrd44 ankyrin repeat domain 44 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of ANKRD44 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ANKRD44 mRNA
CTD PMID:19564919 NCBI chr 1:54,645,340...54,928,983
Ensembl chr 1:54,645,340...54,926,387
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression EXP Methamphetamine results in decreased expression of ANKS1B mRNA CTD PMID:26307267 NCBI chr10:89,872,915...90,973,300
Ensembl chr10:89,873,509...90,973,300
JBrowse link
G Ano3 anoctamin 3 decreases expression ISO Methamphetamine results in decreased expression of ANO3 mRNA CTD PMID:32035215 NCBI chr 2:110,655,201...110,950,391
Ensembl chr 2:110,655,201...110,950,923
JBrowse link
G Ano6 anoctamin 6 increases expression EXP Methamphetamine results in increased expression of ANO6 mRNA CTD PMID:26307267 NCBI chr15:95,790,843...95,975,472
Ensembl chr15:95,790,843...95,974,751
JBrowse link
G Anxa3 annexin A3 decreases expression ISO Methamphetamine results in decreased expression of ANXA3 protein CTD PMID:19826936 NCBI chr 5:96,793,385...96,845,968
Ensembl chr 5:96,793,339...96,845,966
JBrowse link
G Aoah acyloxyacyl hydrolase affects response to substance ISO AOAH gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr13:20,794,103...21,036,617
Ensembl chr13:20,794,113...21,036,617
JBrowse link
G Ap1b1 adaptor protein complex AP-1, beta 1 subunit increases expression EXP Methamphetamine results in increased expression of AP1B1 mRNA CTD PMID:26307267 NCBI chr11:4,947,320...5,042,794
Ensembl chr11:4,986,824...5,042,791
JBrowse link
G Apex2 apurinic/apyrimidinic endonuclease 2 increases expression ISO Methamphetamine results in increased expression of APEX2 mRNA CTD PMID:19149911 NCBI chr  X:150,426,974...150,588,206
Ensembl chr  X:150,519,519...150,589,868
JBrowse link
G Aplnr apelin receptor decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of APLNR mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of APLNR mRNA
CTD PMID:19564919 NCBI chr 2:85,136,360...85,139,923
Ensembl chr 2:85,136,225...85,139,923
JBrowse link
G Apoa2 apolipoprotein A-II decreases expression ISO Methamphetamine results in decreased expression of APOA2 mRNA CTD PMID:32035215 NCBI chr 1:171,221,564...171,226,379
Ensembl chr 1:171,225,054...171,226,379
JBrowse link
G Apod apolipoprotein D decreases expression ISO Methamphetamine results in decreased expression of APOD mRNA CTD PMID:28619521 NCBI chr16:31,296,192...31,314,808
Ensembl chr16:31,296,192...31,314,808
JBrowse link
G Apold1 apolipoprotein L domain containing 1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of APOLD1 mRNA
Methamphetamine results in increased expression of APOLD1 mRNA
CTD PMID:19564919 NCBI chr 6:134,982,001...134,986,836
Ensembl chr 6:134,981,718...134,986,836
JBrowse link
G App amyloid beta (A4) precursor protein multiple interactions
increases expression
increases secretion
ISO Methamphetamine results in increased expression of and results in increased cleavage of APP protein
Methamphetamine results in increased expression of APP protein
Rosiglitazone inhibits the reaction [Methamphetamine results in increased expression of APP protein]
Methamphetamine results in increased secretion of APP protein
CTD PMID:30367931 PMID:31270305 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 increases expression EXP Methamphetamine results in increased expression of APPL2 mRNA CTD PMID:26307267 NCBI chr10:83,600,033...83,648,877
Ensembl chr10:83,600,033...83,648,738
JBrowse link
G Ar androgen receptor increases expression ISO Methamphetamine results in increased expression of AR mRNA CTD PMID:15644446 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 increases expression EXP Methamphetamine results in increased expression of ARAP3 mRNA CTD PMID:26307267 NCBI chr18:37,972,623...37,999,531
Ensembl chr18:37,972,628...37,998,969
JBrowse link
G Arc activity regulated cytoskeletal-associated protein multiple interactions
increases expression
ISO CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA] CTD PMID:11085305 PMID:19564919 PMID:20298714 NCBI chr15:74,669,081...74,672,570
Ensembl chr15:74,669,083...74,672,570
JBrowse link
G Areg amphiregulin decreases expression EXP Methamphetamine results in decreased expression of AREG mRNA CTD PMID:26307267 NCBI chr 5:91,139,599...91,148,432
Ensembl chr 5:91,139,599...91,148,432
JBrowse link
G Arg2 arginase type II multiple interactions
increases expression
ISO Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] CTD PMID:19149911 NCBI chr12:79,130,788...79,156,301
Ensembl chr12:79,130,777...79,156,301
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 increases expression EXP Methamphetamine results in increased expression of ARHGAP29 mRNA CTD PMID:26307267 NCBI chr 3:121,953,113...122,016,677
Ensembl chr 3:121,952,541...122,016,753
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 increases methylation EXP Methamphetamine results in increased methylation of ARHGAP9 promoter CTD PMID:26307267 NCBI chr10:127,321,913...127,329,947
Ensembl chr10:127,321,964...127,329,943
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor (GDI) alpha increases expression ISO Methamphetamine results in increased expression of ARHGDIA protein CTD PMID:19826936 NCBI chr11:120,578,099...120,581,624
Ensembl chr11:120,578,104...120,581,624
JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 increases expression EXP Methamphetamine results in increased expression of ARHGEF1 mRNA CTD PMID:26307267 NCBI chr 7:24,902,986...24,926,594
Ensembl chr 7:24,902,912...24,926,594
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 increases expression EXP Methamphetamine results in increased expression of ARHGEF10 mRNA CTD PMID:26307267 NCBI chr 8:14,906,412...15,001,085
Ensembl chr 8:14,911,663...15,001,085
JBrowse link
G Arhgef15 Rho guanine nucleotide exchange factor (GEF) 15 increases expression EXP Methamphetamine results in increased expression of ARHGEF15 mRNA CTD PMID:26307267 NCBI chr11:68,928,900...68,956,934
Ensembl chr11:68,943,155...68,957,480
JBrowse link
G Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 increases expression EXP Methamphetamine results in increased expression of ARHGEF2 mRNA CTD PMID:26307267 NCBI chr 3:88,593,105...88,649,532
Ensembl chr 3:88,605,966...88,648,052
JBrowse link
G Arhgef25 Rho guanine nucleotide exchange factor (GEF) 25 increases methylation EXP Methamphetamine results in increased methylation of ARHGEF25 promoter CTD PMID:26307267 NCBI chr10:127,182,521...127,190,083
Ensembl chr10:127,182,525...127,190,083
JBrowse link
G Arid1a AT rich interactive domain 1A (SWI-like) increases methylation
increases expression
EXP Methamphetamine results in increased methylation of ARID1A promoter
Methamphetamine results in increased expression of ARID1A mRNA
CTD PMID:26307267 NCBI chr 4:133,679,008...133,756,769
Ensembl chr 4:133,679,008...133,756,769
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 increases expression ISO Methamphetamine results in increased expression of ARIH1 mRNA CTD PMID:19564919 NCBI chr 9:59,388,554...59,488,186
Ensembl chr 9:59,388,258...59,486,618
JBrowse link
G Arl14ep ADP-ribosylation factor-like 14 effector protein decreases expression ISO Methamphetamine results in decreased expression of ARL14EP mRNA CTD PMID:19564919 NCBI chr 2:106,962,529...106,974,397
Ensembl chr 2:106,962,527...106,974,424
JBrowse link
G Arl5b ADP-ribosylation factor-like 5B multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ARL5B mRNA
Methamphetamine results in increased expression of ARL5B mRNA
CTD PMID:19564919 NCBI chr 2:15,055,252...15,082,456
Ensembl chr 2:15,049,395...15,082,456
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 increases expression ISO Methamphetamine results in increased expression of ARNT2 mRNA CTD PMID:15644446 NCBI chr 7:84,246,274...84,411,741
Ensembl chr 7:84,246,278...84,410,176
JBrowse link
G Arrb2 arrestin, beta 2 increases response to substance ISO ARRB2 gene SNP results in increased susceptibility to Methamphetamine CTD PMID:17233643 NCBI chr11:70,432,485...70,440,828
Ensembl chr11:70,432,635...70,440,828
JBrowse link
G Arrdc2 arrestin domain containing 2 increases expression EXP Methamphetamine results in increased expression of ARRDC2 mRNA CTD PMID:26307267 NCBI chr 8:70,835,129...70,839,720
Ensembl chr 8:70,835,129...70,839,720
JBrowse link
G Asb14 ankyrin repeat and SOCS box-containing 14 increases expression EXP Methamphetamine results in increased expression of ASB14 mRNA CTD PMID:26307267 NCBI chr14:26,894,590...26,915,257
Ensembl chr14:26,894,557...26,915,258
JBrowse link
G Asic3 acid-sensing (proton-gated) ion channel 3 increases expression ISO Methamphetamine results in increased expression of ASIC3 mRNA CTD PMID:15644446 NCBI chr 5:24,413,451...24,417,840
Ensembl chr 5:24,413,392...24,417,835
JBrowse link
G Asl argininosuccinate lyase decreases expression ISO Methamphetamine results in decreased expression of ASL mRNA CTD PMID:19564919 NCBI chr 5:130,011,258...130,024,381
Ensembl chr 5:130,011,258...130,029,247
JBrowse link
G Aspm abnormal spindle microtubule assembly decreases expression ISO Methamphetamine results in decreased expression of ASPM mRNA CTD PMID:25290377 NCBI chr 1:139,454,188...139,494,088
Ensembl chr 1:139,454,772...139,494,091
JBrowse link
G Astn2 astrotactin 2 affects response to substance ISO ASTN2 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 4:65,380,803...66,404,537
Ensembl chr 4:65,380,803...66,404,611
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ATF3 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF3 mRNA]
Methamphetamine results in increased expression of ATF3 mRNA; Methamphetamine results in increased expression of ATF3 protein
CTD PMID:19564919 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 protein]
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein]
Methamphetamine results in increased expression of ATF4 mRNA; Methamphetamine results in increased expression of ATF4 protein
CTD PMID:19564919 PMID:27323860 NCBI chr15:80,255,184...80,257,545
Ensembl chr15:80,255,184...80,257,541
JBrowse link
G Atf6 activating transcription factor 6 increases expression
affects localization
increases cleavage
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of ATF6 mRNA; Methamphetamine results in increased expression of ATF6 protein
Methamphetamine affects the localization of ATF6 protein
Methamphetamine results in increased cleavage of ATF6 protein
ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 protein]; Methamphetamine results in decreased expression of and results in increased cleavage of ATF6 protein; Naltrexone inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein]
Melatonin inhibits the reaction [Methamphetamine results in increased expression of ATF6 protein]
CTD PMID:19564919 PMID:27323860 PMID:28070110 NCBI chr 1:170,704,457...170,868,585
Ensembl chr 1:170,704,674...170,867,771
JBrowse link
G Atg14 autophagy related 14 increases expression ISO Methamphetamine results in increased expression of ATG14 mRNA CTD PMID:32676729 NCBI chr14:47,540,893...47,568,434
Ensembl chr14:47,540,893...47,570,649
JBrowse link
G Atg16l1 autophagy related 16-like 1 (S. cerevisiae) increases expression ISO Methamphetamine results in increased expression of ATG16L1 mRNA CTD PMID:32676729 NCBI chr 1:87,756,007...87,792,428
Ensembl chr 1:87,755,870...87,792,428
JBrowse link
G Atg2a autophagy related 2A increases expression ISO Methamphetamine results in increased expression of ATG2A mRNA CTD PMID:32676729 NCBI chr19:6,241,478...6,262,304
Ensembl chr19:6,241,668...6,262,335
JBrowse link
G Atg5 autophagy related 5 increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of ATG5 mRNA; Methamphetamine results in increased expression of ATG5 protein
Luteolin inhibits the reaction [Methamphetamine results in increased expression of ATG5 protein]
CTD PMID:32035215 PMID:32676729 PMID:33359793 NCBI chr10:44,268,322...44,364,299
Ensembl chr10:44,268,358...44,364,291
JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide decreases expression ISO Methamphetamine results in decreased expression of ATP1A1 mRNA CTD PMID:19149911 NCBI chr 3:101,576,219...101,604,707
Ensembl chr 3:101,576,219...101,604,684
JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 multiple interactions
decreases expression
ISO Lithium inhibits the reaction [Methamphetamine results in decreased expression of ATP2A2 mRNA] CTD PMID:19149911 NCBI chr 5:122,453,513...122,502,225
Ensembl chr 5:122,453,513...122,502,225
JBrowse link
G Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit decreases expression ISO Methamphetamine results in decreased expression of ATP5F1B protein CTD PMID:19826936 NCBI chr10:128,083,307...128,090,388
Ensembl chr10:128,083,273...128,090,391
JBrowse link
G Atp5h ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D decreases expression ISO Methamphetamine results in decreased expression of ATP5H protein CTD PMID:17904249 NCBI chr11:115,415,691...115,419,919
Ensembl chr11:115,415,689...115,419,962
JBrowse link
G Atp6v0a1 ATPase, H+ transporting, lysosomal V0 subunit A1 increases expression EXP Methamphetamine results in increased expression of ATP6V0A1 mRNA CTD PMID:26307267 NCBI chr11:101,009,422...101,063,719
Ensembl chr11:101,009,452...101,063,719
JBrowse link
G Atp6v0e2 ATPase, H+ transporting, lysosomal V0 subunit E2 increases expression ISO Methamphetamine results in increased expression of ATP6V0E2 mRNA CTD PMID:32035215 NCBI chr 6:48,537,569...48,541,801
Ensembl chr 6:48,537,615...48,541,801
JBrowse link
G Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 decreases expression ISO
EXP
Methamphetamine results in decreased expression of ATP6V1B2 protein CTD PMID:16181420 PMID:19826936 NCBI chr 8:69,088,736...69,113,718
Ensembl chr 8:69,088,646...69,113,711
JBrowse link
G Atp6v1c2 ATPase, H+ transporting, lysosomal V1 subunit C2 decreases expression ISO Methamphetamine results in decreased expression of ATP6V1C2 mRNA CTD PMID:19564919 NCBI chr12:17,284,721...17,325,386
Ensembl chr12:17,284,721...17,329,359
JBrowse link
G Atxn2l ataxin 2-like increases expression EXP Methamphetamine results in increased expression of ATXN2L mRNA CTD PMID:26307267 NCBI chr 7:126,491,708...126,507,819
Ensembl chr 7:126,491,708...126,503,437
JBrowse link
G Atxn7l1 ataxin 7-like 1 increases expression EXP Methamphetamine results in increased expression of ATXN7L1 mRNA CTD PMID:26307267 NCBI chr12:33,146,968...33,376,408
Ensembl chr12:33,147,693...33,373,185
JBrowse link
G AU021092 expressed sequence AU021092 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of RGD1565166 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RGD1565166 mRNA
CTD PMID:19564919 NCBI chr16:5,211,814...5,222,308
Ensembl chr16:5,211,823...5,222,299
JBrowse link
G Aurkc aurora kinase C decreases expression ISO Methamphetamine results in decreased expression of AURKC mRNA CTD PMID:19564919 NCBI chr 7:6,995,347...7,003,091
Ensembl chr 7:6,995,300...7,003,091
JBrowse link
G Avp arginine vasopressin affects expression
multiple interactions
ISO Methamphetamine affects the expression of AVP mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of AVP mRNA
CTD PMID:19564919 NCBI chr 2:130,580,620...130,582,588
Ensembl chr 2:130,580,620...130,582,554
JBrowse link
G B3galt4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of B3GALT4 mRNA
Methamphetamine results in decreased expression of B3GALT4 mRNA
CTD PMID:19564919 NCBI chr17:33,949,912...33,951,488
Ensembl chr17:33,949,909...33,951,488
JBrowse link
G Bace1 beta-site APP cleaving enzyme 1 increases expression ISO Methamphetamine results in increased expression of BACE1 protein CTD PMID:30367931 NCBI chr 9:45,838,545...45,862,484
Ensembl chr 9:45,838,580...45,864,399
JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 decreases expression EXP Methamphetamine results in decreased expression of BACH2 mRNA CTD PMID:26307267 NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108
JBrowse link
G Baiap3 BAI1-associated protein 3 increases expression ISO Methamphetamine results in increased expression of BAIAP3 mRNA CTD PMID:25290377 NCBI chr17:25,242,659...25,256,364
Ensembl chr17:25,242,659...25,256,364
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
ISO [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAK1 protein
Methamphetamine results in increased expression of BAK1 protein
CTD PMID:23820845 NCBI chr17:27,019,812...27,028,627
Ensembl chr17:27,019,810...27,029,009
JBrowse link
G Banp BTG3 associated nuclear protein increases expression EXP Methamphetamine results in increased expression of BANP mRNA CTD PMID:26307267 NCBI chr 8:121,947,972...122,029,260
Ensembl chr 8:121,949,750...122,029,258
JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression ISO Methamphetamine results in decreased expression of BARD1 mRNA CTD PMID:28341135 NCBI chr 1:71,027,535...71,103,141
Ensembl chr 1:71,027,498...71,103,146
JBrowse link
G Bax BCL2-associated X protein multiple interactions
increases expression
ISO
EXP
BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein]
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of BAX protein]
Methamphetamine results in increased expression of BAX mRNA; Methamphetamine results in increased expression of BAX protein
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX protein; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of BAX protein]
CTD PMID:19149911 PMID:23820845 PMID:26307267 PMID:26524635 PMID:26923100 PMID:29467000 PMID:31059759 PMID:31422080 PMID:32035215 PMID:32203791 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B increases expression EXP Methamphetamine results in increased expression of BAZ1B mRNA CTD PMID:26307267 NCBI chr 5:135,187,323...135,246,131
Ensembl chr 5:135,187,264...135,246,129
JBrowse link
G Baz2a bromodomain adjacent to zinc finger domain, 2A increases expression EXP Methamphetamine results in increased expression of BAZ2A mRNA CTD PMID:26307267 NCBI chr10:128,091,370...128,129,303
Ensembl chr10:128,091,577...128,129,303
JBrowse link
G Bbc3 BCL2 binding component 3 multiple interactions
increases expression
ISO
EXP
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]
Methamphetamine results in increased expression of BBC3 protein
BBC3 protein promotes the reaction [Methamphetamine results in increased expression of NOS2 protein]
Methamphetamine results in increased expression of BBC3 mRNA; Methamphetamine results in increased expression of BBC3 protein
CTD PMID:23820845 PMID:26524635 PMID:30394308 NCBI chr 7:16,308,398...16,318,334
Ensembl chr 7:16,308,393...16,318,205
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 affects response to substance
increases expression
decreases expression
multiple interactions
EXP
ISO
BCL2 protein affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of BCL2 protein
Methamphetamine results in decreased expression of BCL2 protein
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2 mRNA; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]
Methamphetamine results in decreased expression of BCL2 mRNA; Methamphetamine results in decreased expression of BCL2 protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SOD1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]
BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Olanzapine inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]
CTD PMID:11457507 PMID:12050851 PMID:15276877 PMID:19149911 PMID:23820845 PMID:26524635 PMID:26923100 PMID:29467000 PMID:31059759 PMID:31422080 PMID:32203791 PMID:32676729 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2l1 BCL2-like 1 affects expression
multiple interactions
decreases expression
increases methylation
increases expression
ISO
EXP
Methamphetamine affects the expression of BCL2L1 mRNA alternative form
EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]
Methamphetamine results in increased methylation of BCL2L1 promoter
Methamphetamine results in increased expression of BCL2L1 mRNA
Methamphetamine results in decreased expression of BCL2L1 mRNA
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2L1 mRNA
CTD PMID:10336889 PMID:23820845 PMID:26307267 PMID:31422080 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728
JBrowse link
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) multiple interactions
increases expression
ISO [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein
Methamphetamine results in increased expression of BCL2L11 protein
CTD PMID:23820845 NCBI chr 2:128,126,038...128,162,547
Ensembl chr 2:128,126,038...128,162,547
JBrowse link
G Bcl2l15 BCLl2-like 15 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL2L15 mRNA
Methamphetamine results in increased expression of BCL2L15 mRNA
CTD PMID:19564919 NCBI chr 3:103,831,036...103,854,618
Ensembl chr 3:103,832,601...103,854,618
JBrowse link
G Bcl2l2 BCL2-like 2 increases expression EXP Methamphetamine results in increased expression of BCL2L2 mRNA CTD PMID:26307267 NCBI chr14:54,883,366...54,890,858
Ensembl chr14:54,892,500...54,898,169
Ensembl chr14:54,892,500...54,898,169
JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL6 mRNA
Methamphetamine results in increased expression of BCL6 mRNA
CTD PMID:19564919 NCBI chr16:23,965,050...23,988,866
Ensembl chr16:23,965,052...23,988,852
JBrowse link
G Bcl9l B cell CLL/lymphoma 9-like increases expression EXP Methamphetamine results in increased expression of BCL9L mRNA CTD PMID:26307267 NCBI chr 9:44,482,738...44,511,906
Ensembl chr 9:44,482,825...44,511,896
JBrowse link
G Bdnf brain derived neurotrophic factor increases response to substance
decreases expression
multiple interactions
increases expression
affects response to substance
ISO
EXP
BDNF gene SNP results in increased susceptibility to Methamphetamine
Methamphetamine results in decreased expression of BDNF protein
Metformin inhibits the reaction [Methamphetamine results in decreased expression of BDNF protein]
Methamphetamine results in increased expression of BDNF protein
BDNF protein affects the susceptibility to Methamphetamine
BDNF gene polymorphism affects the susceptibility to Methamphetamine
CTD PMID:15050682 PMID:16039058 PMID:19462300 PMID:20736000 PMID:27373168 PMID:30742852 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions
increases expression
increases phosphorylation
ISO
EXP
CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein]
Methamphetamine results in increased phosphorylation of BECN1 protein
DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]
CTD PMID:26825372 PMID:31059759 PMID:32035215 PMID:32676729 PMID:33359793 NCBI chr11:101,288,258...101,302,286
Ensembl chr11:101,285,952...101,302,286
JBrowse link
G Bhmt2 betaine-homocysteine methyltransferase 2 affects expression
multiple interactions
ISO Methamphetamine affects the expression of BHMT2 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of BHMT2 mRNA
CTD PMID:19564919 NCBI chr13:93,656,097...93,674,302
Ensembl chr13:93,655,720...93,674,302
JBrowse link
G Bid BH3 interacting domain death agonist increases expression
multiple interactions
ISO Methamphetamine results in increased expression of BID mRNA; Methamphetamine results in increased expression of BID protein modified form
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form
CTD PMID:23820845 NCBI chr 6:120,893,119...120,917,062
Ensembl chr 6:120,891,930...120,916,853
JBrowse link
G Bin1 bridging integrator 1 decreases expression ISO Methamphetamine results in decreased expression of BIN1 protein CTD PMID:19826936 NCBI chr18:32,376,618...32,435,740
Ensembl chr18:32,377,230...32,435,737
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Methamphetamine results in decreased expression of BIRC5 mRNA CTD PMID:25290377 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Braf Braf transforming gene increases expression ISO Methamphetamine results in increased expression of BRAF mRNA CTD PMID:19564919 NCBI chr 6:39,603,231...39,725,658
Ensembl chr 6:39,603,237...39,725,463
JBrowse link
G Brd2 bromodomain containing 2 increases expression EXP Methamphetamine results in increased expression of BRD2 mRNA CTD PMID:26307267 NCBI chr17:34,112,019...34,122,814
Ensembl chr17:34,112,023...34,122,634
JBrowse link
G Brd9 bromodomain containing 9 increases expression EXP Methamphetamine results in increased expression of BRD9 mRNA CTD PMID:26307267 NCBI chr13:73,937,801...73,960,895
Ensembl chr13:73,937,811...73,960,895
JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 increases expression EXP Methamphetamine results in increased expression of BRWD1 mRNA CTD PMID:26307267 NCBI chr16:95,992,089...96,082,703
Ensembl chr16:95,992,092...96,082,526
JBrowse link
G Bspry B-box and SPRY domain containing decreases expression ISO Methamphetamine results in decreased expression of BSPRY mRNA CTD PMID:19564919 NCBI chr 4:62,480,011...62,497,300
Ensembl chr 4:62,480,053...62,497,298
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression ISO Methamphetamine results in increased expression of BST2 mRNA CTD PMID:32035215 NCBI chr 8:71,534,255...71,537,472
Ensembl chr 8:71,534,255...71,537,456
JBrowse link
G Btaf1 B-TFIID TATA-box binding protein associated factor 1 increases expression ISO Methamphetamine results in increased expression of BTAF1 mRNA CTD PMID:19564919 NCBI chr19:36,926,079...37,014,057
Ensembl chr19:36,926,079...37,012,752
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Methamphetamine results in increased expression of BTG2 mRNA CTD PMID:19564919 NCBI chr 1:134,074,865...134,079,155
Ensembl chr 1:134,075,170...134,079,120
JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase decreases expression ISO Methamphetamine results in decreased expression of BUB1B mRNA CTD PMID:28341135 NCBI chr 2:118,598,202...118,641,592
Ensembl chr 2:118,598,211...118,641,591
JBrowse link
G C1ql1 complement component 1, q subcomponent-like 1 decreases expression ISO Methamphetamine results in decreased expression of C1QL1 mRNA CTD PMID:19564919 NCBI chr11:102,939,264...102,946,716
Ensembl chr11:102,939,264...102,946,688
JBrowse link
G C1qtnf7 C1q and tumor necrosis factor related protein 7 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of C1QTNF7 mRNA
Methamphetamine results in decreased expression of C1QTNF7 mRNA
CTD PMID:19564919 NCBI chr 5:43,515,425...43,619,126
Ensembl chr 5:43,515,538...43,618,803
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 increases expression ISO Methamphetamine results in increased expression of C2CD2 mRNA CTD PMID:19564919 NCBI chr16:97,855,209...97,925,795
Ensembl chr16:97,855,209...97,962,598
JBrowse link
G C8g complement component 8, gamma polypeptide decreases expression ISO Methamphetamine results in decreased expression of C8G mRNA CTD PMID:19564919 NCBI chr 2:25,498,650...25,501,777
Ensembl chr 2:25,498,651...25,501,719
JBrowse link
G Cab39l calcium binding protein 39-like decreases expression EXP Methamphetamine results in decreased expression of CAB39L mRNA CTD PMID:26307267 NCBI chr14:59,440,934...59,548,904
Ensembl chr14:59,440,972...59,585,764
JBrowse link
G Cabin1 calcineurin binding protein 1 increases expression EXP Methamphetamine results in increased expression of CABIN1 mRNA CTD PMID:26307267 NCBI chr10:75,646,110...75,764,357
Ensembl chr10:75,646,112...75,764,341
JBrowse link
G Cabyr calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) increases expression EXP Methamphetamine results in increased expression of CABYR mRNA CTD PMID:26307267 NCBI chr18:12,740,825...12,755,146
Ensembl chr18:12,740,322...12,755,260
JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit decreases methylation
increases expression
EXP Methamphetamine results in decreased methylation of CACNA1C promoter
Methamphetamine results in increased expression of CACNA1C mRNA; Methamphetamine results in increased expression of CACNA1C protein
CTD PMID:26307267 NCBI chr 6:118,587,240...119,197,384
Ensembl chr 6:118,587,240...119,196,890
Ensembl chr 6:118,587,240...119,196,890
JBrowse link
G Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 affects response to substance
increases expression
multiple interactions
EXP CACNA2D1 protein affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of CACNA2D1 mRNA; Methamphetamine results in increased expression of CACNA2D1 protein
[gabapentin binds to and results in decreased activity of CACNA2D1 protein] which results in decreased susceptibility to Methamphetamine; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; gabapentin inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]
CTD PMID:20340177 PMID:21182903 NCBI chr 5:15,934,264...16,374,511
Ensembl chr 5:15,934,691...16,374,511
JBrowse link
G Cacnb4 calcium channel, voltage-dependent, beta 4 subunit increases expression ISO Methamphetamine results in increased expression of CACNB4 mRNA CTD PMID:19564919 NCBI chr 2:52,428,320...52,676,609
Ensembl chr 2:52,428,320...52,676,831
JBrowse link
G Cacybp calcyclin binding protein increases expression ISO Methamphetamine results in increased expression of CACYBP mRNA CTD PMID:19564919 NCBI chr 1:160,202,367...160,212,892
Ensembl chr 1:160,202,367...160,212,875
JBrowse link
G Calb2 calbindin 2 decreases expression ISO Methamphetamine results in decreased expression of CALB2 mRNA CTD PMID:28619521 NCBI chr 8:110,142,526...110,168,212
Ensembl chr 8:110,137,502...110,168,210
JBrowse link
G Calhm2 calcium homeostasis modulator family member 2 increases expression ISO Methamphetamine results in increased expression of CALHM2 mRNA CTD PMID:19564919 NCBI chr19:47,132,232...47,138,294
Ensembl chr19:47,105,353...47,138,294
JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression EXP Methamphetamine results in increased expression of CAMTA2 mRNA CTD PMID:26307267 NCBI chr11:70,669,463...70,688,145
Ensembl chr11:70,669,463...70,688,105
JBrowse link
G Capzb capping protein (actin filament) muscle Z-line, beta decreases expression EXP Methamphetamine results in decreased expression of CAPZB protein CTD PMID:16181420 NCBI chr 4:139,192,899...139,291,820
Ensembl chr 4:139,192,899...139,291,818
JBrowse link
G Car1 carbonic anhydrase 1 increases expression ISO Methamphetamine results in increased expression of CAR1 protein CTD PMID:19826936 NCBI chr 3:14,766,214...14,808,365
Ensembl chr 3:14,766,216...14,808,368
JBrowse link
G Car11 carbonic anhydrase 11 decreases expression ISO Methamphetamine results in decreased expression of CAR11 mRNA CTD PMID:32035215 NCBI chr 7:45,699,171...45,704,687
Ensembl chr 7:45,699,843...45,704,682
JBrowse link
G Car4 carbonic anhydrase 4 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CAR4 mRNA
Methamphetamine results in decreased expression of CAR4 mRNA
CTD PMID:19564919 NCBI chr11:84,957,754...84,966,054
Ensembl chr11:84,957,786...84,966,044
JBrowse link
G Car5b carbonic anhydrase 5b, mitochondrial increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CAR5B mRNA
Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CAR5B mRNA]
CTD PMID:19149911 NCBI chr  X:163,976,822...164,028,010
Ensembl chr  X:163,976,822...164,027,997
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression ISO Methamphetamine results in decreased expression of CARHSP1 mRNA CTD PMID:19564919 NCBI chr16:8,658,580...8,672,153
Ensembl chr16:8,658,580...8,672,155
JBrowse link
G Carns1 carnosine synthase 1 increases expression EXP Methamphetamine results in increased expression of CARNS1 mRNA CTD PMID:26307267 NCBI chr19:4,164,324...4,175,479
Ensembl chr19:4,164,324...4,175,479
JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression
increases cleavage
EXP MIR143 mRNA affects the reaction [Methamphetamine results in increased cleavage of CASP1 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased cleavage of CASP1 protein]
Methamphetamine results in increased expression of CASP1 protein
CTD PMID:30394308 PMID:33359793 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp12 caspase 12 multiple interactions
decreases expression
increases expression
increases cleavage
ISO
EXP
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased cleavage of CASP12 protein]
Methamphetamine results in decreased expression of CASP12 protein
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP12 protein]
Methamphetamine results in increased expression of CASP12 mRNA; Methamphetamine results in increased expression of CASP12 protein
CTD PMID:28070110 PMID:28619521 PMID:29705343 PMID:32203791 NCBI chr 9:5,345,442...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp2 caspase 2 increases expression ISO Methamphetamine results in increased expression of CASP2 mRNA CTD PMID:19564919 NCBI chr 6:42,264,902...42,282,508
Ensembl chr 6:42,264,985...42,282,508
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
decreases expression
increases cleavage
decreases cleavage
affects cleavage
increases expression
EXP
ISO
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; [Methamphetamine co-treated with tin protoporphyrin IX] results in increased cleavage of CASP3 protein; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; JUN protein affects the reaction [Methamphetamine results in increased activity of CASP3 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]
Methamphetamine results in decreased expression of CASP3 protein
Methamphetamine results in decreased cleavage of CASP3 protein
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP3 protein; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP3 protein]
Methamphetamine affects the cleavage of CASP3 protein
BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of CASP3 protein]; KN 93 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; Luteolin inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein; Nifedipine inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; W 7 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; wedelolactone inhibits the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]
Methamphetamine results in increased expression of CASP3 mRNA; Methamphetamine results in increased expression of CASP3 protein modified form
CTD PMID:12391261 PMID:19149911 PMID:19442829 PMID:23933405 PMID:25127757 PMID:25523949 PMID:25631491 PMID:26524635 PMID:26825372 PMID:26923100 PMID:27323860 PMID:28341135 PMID:29467000 PMID:30450033 PMID:31059759 PMID:31422080 PMID:32035215 PMID:32203791 PMID:32382956 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase multiple interactions
increases expression
ISO CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA]
Methamphetamine results in increased expression of CASP4 mRNA; Methamphetamine results in increased expression of CASP4 protein alternative form
CTD PMID:19149911 PMID:25631491 PMID:28619521 NCBI chr 9:5,308,849...5,336,791
Ensembl chr 9:5,308,828...5,336,783
JBrowse link
G Casp6 caspase 6 increases cleavage ISO Methamphetamine results in increased cleavage of CASP6 protein CTD PMID:32676729 NCBI chr 3:129,901,415...129,914,112
Ensembl chr 3:129,901,425...129,914,103
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
ISO ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP9 protein; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein] CTD PMID:27323860 PMID:32676729 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase decreases expression
increases activity
multiple interactions
decreases activity
ISO
EXP
Methamphetamine results in decreased expression of CAT protein
Methamphetamine results in increased activity of CAT protein
ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of CAT protein]
Methamphetamine results in decreased activity of CAT protein
Taurine inhibits the reaction [Methamphetamine results in decreased activity of CAT protein]
CTD PMID:12797468 PMID:19948197 PMID:23041169 PMID:24430743 PMID:29467000 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cav1 caveolin 1, caveolae protein increases expression ISO Methamphetamine results in increased expression of CAV1 mRNA CTD PMID:32035215 NCBI chr 6:17,306,335...17,341,328
Ensembl chr 6:17,306,335...17,341,452
JBrowse link
G Cbll1 Casitas B-lineage lymphoma-like 1 increases expression ISO Methamphetamine results in increased expression of CBLL1 mRNA CTD PMID:19564919 NCBI chr12:31,484,829...31,500,676
Ensembl chr12:31,484,829...31,499,616
JBrowse link
G Cbr1 carbonyl reductase 1 decreases expression ISO Methamphetamine results in decreased expression of CBR1 mRNA CTD PMID:15644446 NCBI chr16:93,607,837...93,610,349
Ensembl chr16:93,605,853...93,610,505
JBrowse link
G Cbx1 chromobox 1 decreases expression EXP Methamphetamine results in decreased expression of CBX1 mRNA CTD PMID:26307267 NCBI chr11:96,788,680...96,808,982
Ensembl chr11:96,789,127...96,808,640
JBrowse link
G Cbx8 chromobox 8 decreases expression ISO Methamphetamine results in decreased expression of CBX8 mRNA CTD PMID:19564919 NCBI chr11:119,036,303...119,040,913
Ensembl chr11:119,036,305...119,040,969
JBrowse link
G Cc2d1b coiled-coil and C2 domain containing 1B multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CC2D1B mRNA
Methamphetamine results in decreased expression of CC2D1B mRNA
CTD PMID:19564919 NCBI chr 4:108,619,940...108,638,604
Ensembl chr 4:108,619,940...108,634,123
JBrowse link
G Ccdc116 coiled-coil domain containing 116 increases expression ISO Methamphetamine results in increased expression of CCDC116 mRNA CTD PMID:19564919 NCBI chr16:17,139,064...17,147,802
Ensembl chr16:17,139,064...17,147,229
JBrowse link
G Ccdc117 coiled-coil domain containing 117 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CCDC117 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CCDC117 mRNA
CTD PMID:19564919 NCBI chr11:5,528,887...5,542,217
Ensembl chr11:5,528,887...5,542,187
JBrowse link
G Ccdc51 coiled-coil domain containing 51 increases methylation EXP Methamphetamine results in increased methylation of CCDC51 promoter CTD PMID:26307267 NCBI chr 9:109,082,496...109,093,363
Ensembl chr 9:109,082,493...109,092,489
JBrowse link
G Ccdc57 coiled-coil domain containing 57 decreases expression ISO Methamphetamine results in decreased expression of CCDC57 mRNA CTD PMID:32035215 NCBI chr11:120,826,529...120,932,926
Ensembl chr11:120,826,529...120,932,872
JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 affects response to substance ISO CCHCR1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr17:35,517,049...35,531,015
Ensembl chr17:35,517,100...35,531,015
JBrowse link
G Cck cholecystokinin multiple interactions ISO
EXP
CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; CCK protein modified form inhibits the reaction [Methamphetamine results in increased phosphorylation of NCF1 protein]
CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]
CTD PMID:27565679 PMID:32916201 NCBI chr 9:121,489,824...121,495,694
Ensembl chr 9:121,489,824...121,495,694
JBrowse link
G Cckbr cholecystokinin B receptor increases expression EXP Methamphetamine results in increased expression of CCKBR mRNA CTD PMID:32916201 NCBI chr 7:105,425,676...105,436,339
Ensembl chr 7:105,425,731...105,470,898
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression ISO Methamphetamine results in increased expression of CCL12 mRNA CTD PMID:28341135 NCBI chr11:82,101,845...82,103,399
Ensembl chr11:82,101,845...82,103,400
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 increases expression ISO Methamphetamine results in increased expression of CCL4 mRNA CTD PMID:19564919 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 decreases expression ISO Methamphetamine results in decreased expression of CCL5 mRNA CTD PMID:19564919 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CCN1 mRNA
Methamphetamine results in increased expression of CCN1 mRNA
CTD PMID:19564919 NCBI chr 3:145,646,971...145,649,985
Ensembl chr 3:145,646,976...145,649,981
JBrowse link
G Ccna1 cyclin A1 multiple interactions
decreases expression
ISO Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCNA1 mRNA] CTD PMID:19149911 NCBI chr 3:55,045,469...55,057,634
Ensembl chr 3:55,045,469...55,055,501
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Methamphetamine results in decreased expression of CCNA2 mRNA; Methamphetamine results in decreased expression of CCNA2 protein CTD PMID:28341135 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Methamphetamine results in decreased expression of CCNB1 mRNA; Methamphetamine results in decreased expression of CCNB1 protein CTD PMID:28341135 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO Methamphetamine results in decreased expression of CCNB2 mRNA
Methamphetamine results in decreased expression of CCNB2 mRNA; Methamphetamine results in decreased expression of CCNB2 protein
CTD PMID:25290377 PMID:28341135 NCBI chr 9:70,407,689...70,421,554
Ensembl chr 9:70,407,692...70,421,547
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of CCND1 mRNA
Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCND1 mRNA]
CTD PMID:19149911 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Methamphetamine results in decreased expression of CCNE1 protein CTD PMID:28341135 NCBI chr 7:38,097,984...38,107,490
Ensembl chr 7:38,097,984...38,107,534
JBrowse link
G Ccnl1 cyclin L1 increases expression ISO Methamphetamine results in increased expression of CCNL1 mRNA CTD PMID:19564919 NCBI chr 3:65,945,908...65,962,029
Ensembl chr 3:65,946,151...65,958,249
JBrowse link
G Ccnl2 cyclin L2 increases expression EXP Methamphetamine results in increased expression of CCNL2 mRNA CTD PMID:26307267 NCBI chr 4:155,810,219...155,824,543
Ensembl chr 4:155,812,489...155,824,543
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 increases response to substance
increases methylation
increases expression
EXP CCR2 protein results in increased susceptibility to Methamphetamine
Methamphetamine results in increased methylation of CCR2 promoter
Methamphetamine results in increased expression of CCR2 mRNA
CTD PMID:20624155 NCBI chr 9:124,101,918...124,109,140
Ensembl chr 9:124,101,950...124,113,557
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of CCR5 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CCR5 mRNA
CTD PMID:19564919 NCBI chr 9:124,121,543...124,127,183
Ensembl chr 9:124,121,543...124,147,699
JBrowse link
G Ccr7 chemokine (C-C motif) receptor 7 decreases expression EXP Methamphetamine results in decreased expression of CCR7 mRNA CTD PMID:26307267 NCBI chr11:99,144,199...99,155,077
Ensembl chr11:99,144,196...99,155,077
JBrowse link
G Cct2 chaperonin containing Tcp1, subunit 2 (beta) decreases expression ISO Methamphetamine results in decreased expression of CCT2 protein CTD PMID:19826936 NCBI chr10:117,050,997...117,063,852
Ensembl chr10:117,051,001...117,063,814
JBrowse link
G Cct5 chaperonin containing Tcp1, subunit 5 (epsilon) decreases expression ISO Methamphetamine results in decreased expression of CCT5 protein CTD PMID:19826936 NCBI chr15:31,590,800...31,601,846
Ensembl chr15:31,590,800...31,601,804
JBrowse link
G Cd151 CD151 antigen increases expression ISO Methamphetamine results in increased expression of CD151 mRNA CTD PMID:32035215 NCBI chr 7:141,467,362...141,471,481
Ensembl chr 7:141,467,392...141,471,473
JBrowse link
G Cd177 CD177 antigen increases expression ISO Methamphetamine results in increased expression of CD177 mRNA CTD PMID:25290377 NCBI chr 7:24,743,983...24,760,334
Ensembl chr 7:24,743,983...24,760,311
JBrowse link
G Cd3d CD3 antigen, delta polypeptide increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CD3D protein
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein]
CTD PMID:29705343 NCBI chr 9:44,981,769...44,987,052
Ensembl chr 9:44,981,786...44,987,339
JBrowse link
G Cd55 CD55 molecule, decay accelerating factor for complement affects response to substance ISO CD55 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 1:130,429,798...130,465,009
Ensembl chr 1:130,439,027...130,462,744
JBrowse link
G Cdc42ep3 CDC42 effector protein (Rho GTPase binding) 3 increases expression ISO Methamphetamine results in increased expression of CDC42EP3 mRNA CTD PMID:19564919 NCBI chr17:79,333,723...79,355,091
Ensembl chr17:79,333,727...79,355,091
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Methamphetamine results in decreased expression of CDC45 mRNA CTD PMID:25290377 NCBI chr16:18,780,447...18,811,972
Ensembl chr16:18,780,447...18,811,987
JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression ISO Methamphetamine results in decreased expression of CDCA3 mRNA; Methamphetamine results in decreased expression of CDCA3 protein CTD PMID:28341135 NCBI chr 6:124,829,530...124,833,701
Ensembl chr 6:124,829,547...124,833,701
JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression EXP Methamphetamine results in decreased expression of CDCA7 mRNA CTD PMID:26307267 NCBI chr 2:72,476,187...72,486,892
Ensembl chr 2:72,476,159...72,486,893
JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO Methamphetamine results in decreased expression of CDCA8 mRNA CTD PMID:25290377 NCBI chr 4:124,918,465...124,936,917
Ensembl chr 4:124,918,465...124,939,311
JBrowse link
G Cdh13 cadherin 13 affects response to substance ISO CDH13 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 8:118,140,017...119,324,929
Ensembl chr 8:118,283,733...119,324,921
JBrowse link
G Cdh5 cadherin 5 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CDH5 mRNA
Luteolin inhibits the reaction [Methamphetamine results in increased expression of CDH5 mRNA]
CTD PMID:32035215 NCBI chr 8:104,101,613...104,144,504
Ensembl chr 8:104,101,625...104,144,511
JBrowse link
G Cdhr2 cadherin-related family member 2 decreases expression ISO Methamphetamine results in decreased expression of CDHR2 mRNA CTD PMID:19564919 NCBI chr13:54,701,463...54,736,662
Ensembl chr13:54,701,461...54,736,662
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
decreases expression
ISO Methamphetamine results in increased expression of CDK1 mRNA
Methamphetamine results in decreased expression of CDK1 mRNA; Methamphetamine results in decreased expression of CDK1 protein
CTD PMID:15644446 PMID:28341135 NCBI chr10:69,335,146...69,352,912
Ensembl chr10:69,335,146...69,352,938
JBrowse link
G Cdk10 cyclin-dependent kinase 10 decreases expression ISO Methamphetamine results in decreased expression of CDK10 mRNA CTD PMID:19564919 NCBI chr 8:123,224,841...123,232,256
Ensembl chr 8:123,224,842...123,232,250
JBrowse link
G Cdk5 cyclin-dependent kinase 5 multiple interactions
increases expression
ISO
EXP
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]
Methamphetamine results in increased expression of CDK5 protein
SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of CDK5 protein]
CTD PMID:29705343 PMID:32278788 NCBI chr 5:24,407,597...24,423,587
Ensembl chr 5:24,418,241...24,423,530
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO Methamphetamine results in increased expression of CDK6 mRNA CTD PMID:19564919 NCBI chr 5:3,341,004...3,531,008
Ensembl chr 5:3,341,485...3,531,008
JBrowse link
G Cdk9 cyclin-dependent kinase 9 (CDC2-related kinase) increases expression EXP Methamphetamine results in increased expression of CDK9 mRNA CTD PMID:26307267 NCBI chr 2:32,705,782...32,712,784
Ensembl chr 2:32,705,784...32,713,076
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CDKN1A mRNA
Methamphetamine results in increased expression of CDKN1A mRNA
CTD PMID:19564919 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B increases expression ISO Methamphetamine results in increased expression of CDKN2B mRNA CTD PMID:15644446 NCBI chr 4:89,306,289...89,311,032
Ensembl chr 4:89,306,299...89,311,039
JBrowse link
G Cdpf1 cysteine rich, DPF motif domain containing 1 decreases expression ISO Methamphetamine results in decreased expression of CDPF1 mRNA CTD PMID:19564919 NCBI chr15:85,806,972...85,811,697
Ensembl chr15:85,806,972...85,811,697
JBrowse link
G Cdr2 cerebellar degeneration-related 2 increases expression ISO Methamphetamine results in increased expression of CDR2 mRNA CTD PMID:19564919 NCBI chr 7:120,957,036...120,982,312
Ensembl chr 7:120,957,036...120,982,312
JBrowse link
G Cds2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 increases expression EXP Methamphetamine results in increased expression of CDS2 mRNA CTD PMID:26307267 NCBI chr 2:132,253,338...132,312,050
Ensembl chr 2:132,263,148...132,312,050
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CEBPB mRNA; Methamphetamine results in increased expression of CEBPB protein
CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]
[Methamphetamine co-treated with SCH 23390] results in increased expression of CEBPB mRNA; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein]
CTD PMID:19564919 PMID:31059759 NCBI chr 2:167,688,915...167,690,432
Ensembl chr 2:167,688,915...167,690,418
JBrowse link
G Cela1 chymotrypsin-like elastase family, member 1 decreases expression EXP Methamphetamine results in decreased expression of CELA1 mRNA CTD PMID:26307267 NCBI chr15:100,674,422...100,687,920
Ensembl chr15:100,674,421...100,687,921
JBrowse link
G Cenph centromere protein H decreases expression ISO Methamphetamine results in decreased expression of CENPH mRNA CTD PMID:28341135 NCBI chr13:100,759,674...100,775,903
Ensembl chr13:100,759,674...100,775,899
JBrowse link
G Cenpq centromere protein Q decreases expression ISO Methamphetamine results in decreased expression of CENPQ mRNA CTD PMID:28341135 NCBI chr17:40,920,809...40,934,574
Ensembl chr17:40,923,051...40,935,047
JBrowse link
G Cenpw centromere protein W decreases expression ISO Methamphetamine results in decreased expression of CENPW mRNA CTD PMID:28341135 NCBI chr10:30,196,009...30,200,603
Ensembl chr10:30,194,569...30,200,560
JBrowse link
G Cep104 centrosomal protein 104 multiple interactions
affects expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CEP104 mRNA
Methamphetamine affects the expression of CEP104 mRNA
CTD PMID:19564919 NCBI chr 4:153,975,126...154,008,732
Ensembl chr 4:153,975,194...154,008,732
JBrowse link
G Cep55 centrosomal protein 55 decreases expression ISO Methamphetamine results in decreased expression of CEP55 mRNA CTD PMID:25290377 NCBI chr19:38,054,970...38,074,425
Ensembl chr19:38,055,011...38,074,423
JBrowse link
G Cep72 centrosomal protein 72 decreases expression ISO Methamphetamine results in decreased expression of CEP72 mRNA CTD PMID:28341135 NCBI chr13:74,036,495...74,062,319
Ensembl chr13:74,036,500...74,062,299
JBrowse link
G Cep95 centrosomal protein 95 decreases expression ISO Methamphetamine results in decreased expression of CEP95 mRNA CTD PMID:19564919 NCBI chr11:106,788,640...106,818,861
Ensembl chr11:106,789,252...106,819,930
JBrowse link
G Cert1 ceramide transporter 1 increases expression ISO Methamphetamine results in increased expression of CERT1 mRNA CTD PMID:19564919 NCBI chr13:96,542,709...96,640,167
Ensembl chr13:96,542,618...96,640,167
JBrowse link
G Cggbp1 CGG triplet repeat binding protein 1 increases expression ISO Methamphetamine results in increased expression of CGGBP1 mRNA CTD PMID:19564919 NCBI chr16:64,852,001...64,859,491
Ensembl chr16:64,851,996...64,859,507
JBrowse link
G Chac1 ChaC, cation transport regulator 1 increases expression ISO Methamphetamine results in increased expression of CHAC1 mRNA CTD PMID:28619521 NCBI chr 2:119,351,242...119,354,326
Ensembl chr 2:119,351,229...119,354,381
JBrowse link
G Chat choline acetyltransferase decreases activity ISO Methamphetamine results in decreased activity of CHAT protein CTD PMID:10089005 NCBI chr14:32,408,203...32,465,909
Ensembl chr14:32,408,203...32,465,989
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 decreases methylation
increases expression
EXP Methamphetamine results in decreased methylation of CHD4 promoter
Methamphetamine results in increased expression of CHD4 mRNA
CTD PMID:26307267 NCBI chr 6:125,095,980...125,130,591
Ensembl chr 6:125,095,981...125,130,591
JBrowse link
G Cherp calcium homeostasis endoplasmic reticulum protein increases expression EXP Methamphetamine results in increased expression of CHERP mRNA CTD PMID:26307267 NCBI chr 8:72,460,483...72,475,233
Ensembl chr 8:72,460,489...72,475,226
JBrowse link
G Chkb choline kinase beta increases expression EXP Methamphetamine results in increased expression of CHKB mRNA CTD PMID:26307267 NCBI chr15:89,426,349...89,429,927
Ensembl chr15:89,426,360...89,429,908
JBrowse link
G Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CHORDC1 mRNA
Methamphetamine results in increased expression of CHORDC1 mRNA
CTD PMID:19564919 NCBI chr 9:18,292,267...18,314,000
Ensembl chr 9:18,292,125...18,317,442
JBrowse link
G Chrnb1 cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) increases expression ISO Methamphetamine results in increased expression of CHRNB1 mRNA CTD PMID:19564919 NCBI chr11:69,784,036...69,795,966
Ensembl chr11:69,784,036...69,795,943
JBrowse link
G Chrne cholinergic receptor, nicotinic, epsilon polypeptide multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CHRNE mRNA
Methamphetamine results in increased expression of CHRNE mRNA
CTD PMID:19564919 NCBI chr11:70,614,883...70,619,213
Ensembl chr11:70,614,883...70,619,216
JBrowse link
G Chtf18 CTF18, chromosome transmission fidelity factor 18 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CHTF18 mRNA
Methamphetamine results in decreased expression of CHTF18 mRNA
CTD PMID:19564919 NCBI chr17:25,719,030...25,727,434
Ensembl chr17:25,718,926...25,727,419
JBrowse link
G Cic capicua transcriptional repressor increases expression EXP Methamphetamine results in increased expression of CIC mRNA CTD PMID:26307267 NCBI chr 7:25,267,658...25,294,159
Ensembl chr 7:25,267,704...25,294,159
JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A increases expression ISO Methamphetamine results in increased expression of CIDEA mRNA; Methamphetamine results in increased expression of CIDEA protein CTD PMID:28341135 NCBI chr18:67,343,564...67,367,794
Ensembl chr18:67,343,604...67,367,785
JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Methamphetamine results in decreased expression of CIRBP mRNA CTD PMID:19564919 NCBI chr10:80,165,990...80,172,786
Ensembl chr10:80,165,985...80,172,786
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO Methamphetamine results in increased expression of CITED2 mRNA CTD PMID:19564919 NCBI chr10:17,723,228...17,725,674
Ensembl chr10:17,723,218...17,725,674
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CITED4 mRNA
Methamphetamine results in decreased expression of CITED4 mRNA
CTD PMID:19564919 NCBI chr 4:120,666,563...120,667,820
Ensembl chr 4:120,666,572...120,667,820
JBrowse link
G Ckap2 cytoskeleton associated protein 2 decreases expression ISO Methamphetamine results in decreased expression of CKAP2 mRNA CTD PMID:28341135 NCBI chr 8:22,168,149...22,185,819
Ensembl chr 8:22,168,160...22,185,819
JBrowse link
G Ckb creatine kinase, brain increases expression ISO Methamphetamine results in increased expression of CKB protein CTD PMID:19826936 NCBI chr12:111,669,355...111,672,338
Ensembl chr12:111,669,361...111,672,338
JBrowse link
G Clasrp CLK4-associating serine/arginine rich protein increases expression
decreases expression
EXP
ISO
Methamphetamine results in increased expression of SFRS16 mRNA
Methamphetamine results in decreased expression of CLASRP mRNA
CTD PMID:26307267 PMID:32035215 NCBI chr 7:19,581,038...19,604,517
Ensembl chr 7:19,581,035...19,604,486
JBrowse link
G Clcn6 chloride channel, voltage-sensitive 6 increases expression EXP Methamphetamine results in increased expression of CLCN6 mRNA CTD PMID:26307267 NCBI chr 4:148,004,259...148,038,813
Ensembl chr 4:148,004,259...148,038,821
JBrowse link
G Clcnkb chloride channel, voltage-sensitive Kb decreases expression
affects methylation
EXP Methamphetamine results in decreased expression of CLCNKB mRNA
Methamphetamine affects the methylation of CLCNKB promoter
CTD PMID:26307267 NCBI chr 4:141,404,357...141,416,055
Ensembl chr 4:141,404,353...141,416,014
JBrowse link
G Cldn5 claudin 5 decreases expression ISO Methamphetamine results in decreased expression of CLDN5 mRNA CTD PMID:19564919 NCBI chr16:18,776,847...18,778,262
Ensembl chr16:18,776,847...18,778,262
JBrowse link
G Clec4e C-type lectin domain family 4, member e decreases expression EXP Methamphetamine results in decreased expression of CLEC4E mRNA CTD PMID:26307267 NCBI chr 6:123,281,789...123,289,871
Ensembl chr 6:123,281,789...123,289,870
JBrowse link
G Clic4 chloride intracellular channel 4 (mitochondrial) increases expression ISO Methamphetamine results in increased expression of CLIC4 mRNA CTD PMID:19149911 NCBI chr 4:135,213,969...135,272,760
Ensembl chr 4:135,213,969...135,272,814
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression EXP
ISO
Methamphetamine results in increased expression of CLIP1 mRNA CTD PMID:19564919 PMID:26307267 NCBI chr 5:123,577,794...123,684,606
Ensembl chr 5:123,577,795...123,684,618
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit increases expression ISO Methamphetamine results in increased expression of CLPX mRNA CTD PMID:19149911 NCBI chr 9:65,294,251...65,330,658
Ensembl chr 9:65,294,260...65,330,658
JBrowse link
G Cluh clustered mitochondria (cluA/CLU1) homolog increases expression EXP Methamphetamine results in increased expression of CLUH mRNA CTD PMID:26307267 NCBI chr11:74,648,881...74,670,854
Ensembl chr11:74,649,495...74,670,847
JBrowse link
G Clvs2 clavesin 2 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CLVS2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CLVS2 mRNA
CTD PMID:19564919 NCBI chr10:33,512,286...33,624,684
Ensembl chr10:33,512,286...33,624,769
JBrowse link
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 decreases methylation EXP Methamphetamine results in decreased methylation of CMTM3 promoter CTD PMID:26307267 NCBI chr 8:104,339,383...104,347,672
Ensembl chr 8:104,339,410...104,347,672
JBrowse link
G Cmtm8 CKLF-like MARVEL transmembrane domain containing 8 decreases expression ISO Methamphetamine results in decreased expression of CMTM8 mRNA CTD PMID:19564919 NCBI chr 9:114,789,343...114,844,152
Ensembl chr 9:114,789,345...114,844,156
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CNOT6L mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CNOT6L mRNA
CTD PMID:19564919 NCBI chr 5:96,070,333...96,164,198
Ensembl chr 5:96,070,333...96,164,171
JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) affects response to substance ISO CNR1 protein affects the susceptibility to Methamphetamine CTD PMID:17953657 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Cntfr ciliary neurotrophic factor receptor increases expression EXP Methamphetamine results in increased expression of CNTFR mRNA CTD PMID:26307267 NCBI chr 4:41,657,498...41,697,091
Ensembl chr 4:41,657,498...41,697,089
JBrowse link
G Cntn2 contactin 2 decreases expression ISO Methamphetamine results in decreased expression of CNTN2 mRNA CTD PMID:19564919 NCBI chr 1:132,509,425...132,543,251
Ensembl chr 1:132,509,427...132,543,256
JBrowse link
G Cntnap5a contactin associated protein-like 5A decreases expression EXP Methamphetamine results in decreased expression of CNTNAP5A mRNA CTD PMID:26307267 NCBI chr 1:115,684,737...116,587,323
Ensembl chr 1:115,684,756...116,587,323
JBrowse link
G Col10a1 collagen, type X, alpha 1 increases expression ISO Methamphetamine results in increased expression of COL10A1 mRNA CTD PMID:28341135 NCBI chr10:34,389,981...34,397,085
Ensembl chr10:34,389,981...34,397,085
JBrowse link
G Col25a1 collagen, type XXV, alpha 1 decreases expression EXP Methamphetamine results in decreased expression of COL25A1 mRNA CTD PMID:26307267 NCBI chr 3:130,180,358...130,599,884
Ensembl chr 3:130,131,501...130,599,877
JBrowse link
G Col28a1 collagen, type XXVIII, alpha 1 affects response to substance ISO COL28A1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 6:7,997,100...8,193,709
Ensembl chr 6:7,997,808...8,192,617
JBrowse link
G Col3a1 collagen, type III, alpha 1 decreases expression ISO Methamphetamine results in decreased expression of COL3A1 mRNA CTD PMID:19564919 NCBI chr 1:45,311,538...45,349,706
Ensembl chr 1:45,311,538...45,349,706
JBrowse link
G Comt catechol-O-methyltransferase increases response to substance
affects response to substance
ISO COMT gene polymorphism results in increased susceptibility to Methamphetamine
COMT gene polymorphism affects the susceptibility to Methamphetamine
CTD PMID:15274053 PMID:19462300 NCBI chr16:18,406,882...18,426,716
Ensembl chr16:18,406,886...18,426,852
JBrowse link
G Copb2 coatomer protein complex, subunit beta 2 (beta prime) increases expression ISO Methamphetamine results in increased expression of COPB2 mRNA CTD PMID:32035215 NCBI chr 9:98,563,731...98,588,375
Ensembl chr 9:98,563,721...98,588,382
JBrowse link
G Coq10b coenzyme Q10B multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of COQ10B mRNA
Methamphetamine results in increased expression of COQ10B mRNA
CTD PMID:19564919 NCBI chr 1:55,052,770...55,072,702
Ensembl chr 1:55,052,770...55,072,702
JBrowse link
G Coq8a coenzyme Q8A increases expression
decreases methylation
EXP Methamphetamine results in increased expression of COQ8A mRNA
Methamphetamine results in decreased methylation of COQ8A promoter
CTD PMID:26307267 NCBI chr 1:180,165,238...180,196,020
Ensembl chr 1:180,165,238...180,199,602
JBrowse link
G Coro6 coronin 6 increases expression EXP Methamphetamine results in increased expression of CORO6 mRNA CTD PMID:26307267 NCBI chr11:77,462,321...77,470,484
Ensembl chr11:77,462,411...77,470,484
JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 increases expression EXP Methamphetamine results in increased expression of COX10 mRNA CTD PMID:26307267 NCBI chr11:63,962,627...64,079,472
Ensembl chr11:63,962,627...64,079,468
JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 increases expression EXP Methamphetamine results in increased expression of CPEB3 mRNA CTD PMID:26307267 NCBI chr19:37,019,341...37,207,620
Ensembl chr19:37,021,291...37,208,601
JBrowse link
G Cplx1 complexin 1 increases expression ISO Methamphetamine results in increased expression of CPLX1 protein CTD PMID:19826936 NCBI chr 5:108,518,554...108,550,027
Ensembl chr 5:108,518,554...108,550,024
JBrowse link
G Cplx2 complexin 2 increases expression ISO Methamphetamine results in increased expression of CPLX2 protein CTD PMID:19826936 NCBI chr13:54,301,964...54,383,923
Ensembl chr13:54,371,349...54,383,917
JBrowse link
G Cptp ceramide-1-phosphate transfer protein decreases methylation EXP Methamphetamine results in decreased methylation of CPTP promoter CTD PMID:26307267 NCBI chr 4:155,864,723...155,869,440
Ensembl chr 4:155,864,723...155,869,440
JBrowse link
G Cpz carboxypeptidase Z increases expression ISO Methamphetamine results in increased expression of CPZ mRNA CTD PMID:15644446 NCBI chr 5:35,502,218...35,525,626
Ensembl chr 5:35,502,218...35,525,698
JBrowse link
G Crabp1 cellular retinoic acid binding protein I decreases expression ISO Methamphetamine results in decreased expression of CRABP1 mRNA CTD PMID:32035215 NCBI chr 9:54,764,748...54,773,110
Ensembl chr 9:54,764,748...54,773,110
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases expression
ISO Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein
Methamphetamine results in increased expression of CREB1 mRNA; Methamphetamine results in increased expression of CREB1 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 protein]
CTD PMID:30742852 PMID:33421459 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 increases expression ISO Methamphetamine results in increased expression of CRELD2 mRNA CTD PMID:19564919 NCBI chr15:88,819,646...88,826,681
Ensembl chr15:88,819,646...88,826,683
JBrowse link
G Crem cAMP responsive element modulator multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CREM mRNA
Methamphetamine results in increased expression of CREM mRNA
CTD PMID:19564919 NCBI chr18:3,266,354...3,337,773
Ensembl chr18:3,266,048...3,337,748
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CRH mRNA
Methamphetamine results in increased expression of CRH mRNA
CTD PMID:19564919 NCBI chr 3:19,693,401...19,695,396
Ensembl chr 3:19,693,401...19,695,396
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 multiple interactions ISO [CP 154526 binds to and results in decreased activity of CRHR1 protein] which results in decreased susceptibility to Methamphetamine CTD PMID:17119930 NCBI chr11:104,130,463...104,175,523
Ensembl chr11:104,132,855...104,175,523
JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CRISPLD1 mRNA
Methamphetamine results in decreased expression of CRISPLD1 mRNA
CTD PMID:19564919 NCBI chr 1:17,727,029...17,767,235
Ensembl chr 1:17,727,045...17,766,344
JBrowse link
G Crk v-crk avian sarcoma virus CT10 oncogene homolog decreases expression ISO Methamphetamine results in decreased expression of CRK protein CTD PMID:19826936 NCBI chr11:75,679,194...75,708,428
Ensembl chr11:75,679,259...75,706,908
JBrowse link
G Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like increases expression ISO Methamphetamine results in increased expression of CRKL mRNA CTD PMID:19564919 NCBI chr16:17,451,985...17,487,440
Ensembl chr16:17,451,987...17,487,434
JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 increases expression EXP Methamphetamine results in increased expression of CRTC2 mRNA CTD PMID:26307267 NCBI chr 3:90,253,858...90,264,125
Ensembl chr 3:90,254,163...90,264,125
JBrowse link
G Cry1 cryptochrome 1 (photolyase-like) decreases expression ISO Methamphetamine results in decreased expression of CRY1 mRNA CTD PMID:19149911 NCBI chr10:85,131,700...85,185,054
Ensembl chr10:85,131,700...85,185,064
JBrowse link
G Cryab crystallin, alpha B increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CRYAB mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CRYAB mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CRYAB mRNA]
CTD PMID:19564919 NCBI chr 9:50,745,951...50,756,636
Ensembl chr 9:50,751,325...50,756,636
JBrowse link
G Crym crystallin, mu increases expression ISO Methamphetamine results in increased expression of CRYM protein CTD PMID:19826936 NCBI chr 7:120,186,380...120,201,989
Ensembl chr 7:120,186,380...120,202,111
JBrowse link
G Cs citrate synthase increases expression ISO Methamphetamine results in increased expression of CS mRNA CTD PMID:19149911 NCBI chr10:128,337,727...128,362,482
Ensembl chr10:128,337,734...128,362,479
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) increases expression EXP Methamphetamine results in increased expression of CSF1 mRNA CTD PMID:26307267 NCBI chr 3:107,741,048...107,760,469
Ensembl chr 3:107,741,048...107,760,469
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Methamphetamine results in increased expression of CSF1R mRNA CTD PMID:32035215 NCBI chr18:61,105,572...61,131,139
Ensembl chr18:61,100,598...61,132,149
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 affects response to substance ISO CSMD1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 8:15,892,538...17,535,385
Ensembl chr 8:15,892,537...17,535,586
JBrowse link
G Csn1s1 casein alpha s1 increases expression ISO Methamphetamine results in increased expression of CSN1S1 mRNA CTD PMID:28341135 NCBI chr 5:87,666,208...87,682,578
Ensembl chr 5:87,666,208...87,682,578
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of CSRP2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CSRP2 mRNA
CTD PMID:19564919 NCBI chr10:110,920,176...110,939,514
Ensembl chr10:110,919,789...110,939,622
JBrowse link
G Cst11 cystatin 11 increases methylation EXP Methamphetamine results in increased methylation of CST11 promoter CTD PMID:26307267 NCBI chr 2:148,768,618...148,771,497
Ensembl chr 2:148,768,609...148,771,497
JBrowse link
G Cstb cystatin B affects expression ISO Methamphetamine affects the expression of CSTB protein CTD PMID:17904249 NCBI chr10:78,425,670...78,427,622
Ensembl chr10:78,425,669...78,427,622
JBrowse link
G Ctbp2 C-terminal binding protein 2 decreases methylation
increases expression
EXP Methamphetamine results in decreased methylation of CTBP2 promoter
Methamphetamine results in increased expression of CTBP2 mRNA
CTD PMID:26307267 NCBI chr 7:132,986,998...133,124,009
Ensembl chr 7:132,987,563...133,124,354
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 multiple interactions
increases expression
ISO Lithium inhibits the reaction [Methamphetamine results in increased expression of CTNNB1 mRNA] CTD PMID:19149911 PMID:32035215 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Ctrl chymotrypsin-like increases expression ISO Methamphetamine results in increased expression of CTRL mRNA CTD PMID:19564919 NCBI chr 8:105,931,994...105,933,862
Ensembl chr 8:105,932,003...105,933,862
JBrowse link
G Ctsd cathepsin D affects localization ISO Methamphetamine affects the localization of CTSD protein CTD PMID:17105920 NCBI chr 7:142,375,910...142,387,827
Ensembl chr 7:142,375,911...142,388,038
JBrowse link
G Cubn cubilin (intrinsic factor-cobalamin receptor) affects response to substance ISO CUBN gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 2:13,276,338...13,491,876
Ensembl chr 2:13,276,338...13,491,813
JBrowse link
G Cuedc1 CUE domain containing 1 increases expression EXP Methamphetamine results in increased expression of CUEDC1 mRNA CTD PMID:26307267 NCBI chr11:88,099,146...88,194,140
Ensembl chr11:88,098,058...88,194,140
JBrowse link
G Cul2 cullin 2 decreases expression ISO Methamphetamine results in decreased expression of CUL2 mRNA CTD PMID:19564919 NCBI chr18:3,382,970...3,436,700
Ensembl chr18:3,382,988...3,436,377
JBrowse link
G Cul9 cullin 9 increases expression EXP Methamphetamine results in increased expression of CUL9 mRNA CTD PMID:26307267 NCBI chr17:46,500,609...46,546,388
Ensembl chr17:46,500,572...46,546,388
JBrowse link
G Cux1 cut-like homeobox 1 increases expression ISO Methamphetamine results in increased expression of CUX1 mRNA CTD PMID:19564919 NCBI chr 5:136,248,135...136,567,590
Ensembl chr 5:136,248,135...136,567,490
JBrowse link
G Cwc25 CWC25 spliceosome-associated protein increases expression ISO Methamphetamine results in increased expression of CWC25 mRNA CTD PMID:19564919 NCBI chr11:97,745,470...97,766,613
Ensembl chr11:97,745,481...97,766,556
JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 decreases expression ISO Methamphetamine results in decreased expression of CX3CR1 mRNA CTD PMID:19564919 NCBI chr 9:120,048,683...120,068,296
Ensembl chr 9:119,901,616...120,069,879
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 increases expression ISO Methamphetamine results in increased expression of CXCL10 mRNA CTD PMID:25290377 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889
JBrowse link
G Cxcl12 chemokine (C-X-C motif) ligand 12 multiple interactions
increases expression
ISO Luteolin inhibits the reaction [Methamphetamine results in increased expression of CXCL12 mRNA] CTD PMID:32035215 NCBI chr 6:117,168,535...117,181,368
Ensembl chr 6:117,168,535...117,181,367
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 increases expression ISO Methamphetamine results in increased expression of CXCL2 mRNA CTD PMID:25290377 NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938
JBrowse link
G Cyb5b cytochrome b5 type B increases expression ISO Methamphetamine results in increased expression of CYB5B mRNA CTD PMID:19149911 NCBI chr 8:107,150,661...107,187,470
Ensembl chr 8:107,150,640...107,187,471
JBrowse link
G Cybb cytochrome b-245, beta polypeptide multiple interactions ISO CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein] CTD PMID:27565679 NCBI chr  X:9,435,252...9,487,766
Ensembl chr  X:9,435,252...9,487,771
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO Methamphetamine results in increased expression of CYCS mRNA CTD PMID:19149911 NCBI chr 6:50,562,563...50,566,569
Ensembl chr 6:50,562,563...50,566,538
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression ISO Methamphetamine results in increased expression of CYP11A1 mRNA CTD PMID:19149911 NCBI chr 9:57,998,024...58,027,031
Ensembl chr 9:58,006,411...58,027,023
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing ISO CYP1A2 protein affects the metabolism of Methamphetamine metabolite CTD PMID:16038959 NCBI chr 9:57,676,937...57,683,655
Ensembl chr 9:57,676,937...57,683,703
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
decreases expression
ISO Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of CYP27A1 mRNA] CTD PMID:19149911 NCBI chr 1:74,713,148...74,737,897
Ensembl chr 1:74,713,574...74,737,892
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 affects response to substance
increases metabolic processing
ISO CYP2D4 gene polymorphism affects the susceptibility to Methamphetamine; CYP2D6 protein affects the susceptibility to Methamphetamine
CYP2D6 protein results in increased metabolism of Methamphetamine
CTD PMID:18280655 PMID:20727252 PMID:27320963 NCBI chr15:82,370,527...82,380,260
Ensembl chr15:82,370,527...82,380,260
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing ISO CYP2E1 protein affects the metabolism of Methamphetamine metabolite CTD PMID:16038959 NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G Cyp4f13 cytochrome P450, family 4, subfamily f, polypeptide 13 increases expression EXP Methamphetamine results in increased expression of CYP4F13 mRNA CTD PMID:26307267 NCBI chr17:32,924,688...32,947,415
Ensembl chr17:32,924,688...32,947,402
JBrowse link
G Cyth1 cytohesin 1 increases expression EXP Methamphetamine results in increased expression of CYTH1 mRNA CTD PMID:26307267 NCBI chr11:118,164,170...118,248,616
Ensembl chr11:118,132,019...118,248,592
JBrowse link
G Cyyr1 cysteine and tyrosine-rich protein 1 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CYYR1 mRNA
Methamphetamine results in decreased expression of CYYR1 mRNA
CTD PMID:19564919 NCBI chr16:85,452,858...85,550,905
Ensembl chr16:85,421,533...85,553,397
JBrowse link
G Czib CXXC motif containing zinc binding protein decreases expression ISO Methamphetamine results in decreased expression of CZIB mRNA CTD PMID:19564919 NCBI chr 4:107,889,785...107,897,803
Ensembl chr 4:107,889,813...107,899,384
JBrowse link
G Dad1 defender against cell death 1 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of DAD1 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DAD1 mRNA]
CTD PMID:19564919 NCBI chr14:54,235,485...54,253,929
Ensembl chr14:54,235,479...54,254,104
JBrowse link
G Dbh dopamine beta hydroxylase decreases expression ISO Methamphetamine results in decreased expression of DBH protein CTD PMID:28661099 NCBI chr 2:27,165,507...27,183,204
Ensembl chr 2:27,165,233...27,183,200
JBrowse link
G Dbp D site albumin promoter binding protein increases expression EXP Methamphetamine results in increased expression of DBP mRNA CTD PMID:26307267 NCBI chr 7:45,705,100...45,710,203
Ensembl chr 7:45,705,088...45,710,203
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein affects response to substance ISO DCSTAMP gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr15:39,745,930...39,760,938
Ensembl chr15:39,745,930...39,760,938
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 affects expression ISO Methamphetamine affects the expression of DDAH1 protein CTD PMID:17904249 NCBI chr 3:145,758,692...145,894,277
Ensembl chr 3:145,758,675...145,894,277
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO
EXP
[Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT3 mRNA; Melatonin inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]
ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]
Methamphetamine results in increased expression of DDIT3 mRNA; Methamphetamine results in increased expression of DDIT3 protein
CTD PMID:15644446 PMID:19564919 PMID:27323860 PMID:28070110 PMID:28619521 PMID:32203791 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression
increases response to substance
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT4 mRNA; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of PARP1 protein modified form]
DDIT4 protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein]
Methamphetamine results in increased expression of DDIT4 mRNA; Methamphetamine results in increased expression of DDIT4 protein
DDIT4 protein results in increased susceptibility to Methamphetamine
CTD PMID:19564919 PMID:26825372 PMID:31059759 NCBI chr10:59,949,675...59,951,770
Ensembl chr10:59,949,669...59,951,834
JBrowse link
G Ddt D-dopachrome tautomerase affects expression ISO Methamphetamine affects the expression of DDT protein CTD PMID:17904249 NCBI chr10:75,771,233...75,773,374
Ensembl chr10:75,771,230...75,773,414
JBrowse link
G Ddx10 DEAD box helicase 10 increases expression ISO Methamphetamine results in increased expression of DDX10 mRNA CTD PMID:19149911 NCBI chr 9:53,098,454...53,248,170
Ensembl chr 9:53,098,635...53,248,053
JBrowse link
G Ddx17 DEAD box helicase 17 increases expression EXP Methamphetamine results in increased expression of DDX17 mRNA CTD PMID:26307267 NCBI chr15:79,527,696...79,546,764
Ensembl chr15:79,527,736...79,546,741
JBrowse link
G Ddx21 DExD box helicase 21 multiple interactions
decreases expression
ISO Lithium inhibits the reaction [Methamphetamine results in decreased expression of DDX21 mRNA] CTD PMID:19149911 NCBI chr10:62,580,247...62,602,298
Ensembl chr10:62,580,251...62,602,281
JBrowse link
G Ddx52 DExD box helicase 52 decreases expression ISO Methamphetamine results in decreased expression of DDX52 mRNA CTD PMID:19564919 NCBI chr11:83,942,090...83,963,088
Ensembl chr11:83,942,062...83,963,088
JBrowse link
G Ddx58 DEAD/H box helicase 58 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of DDX58 mRNA
Methamphetamine results in decreased expression of DDX58 mRNA
CTD PMID:19564919 NCBI chr 4:40,203,777...40,239,825
Ensembl chr 4:40,203,773...40,239,828
JBrowse link
G Deaf1 DEAF1, transcription factor increases expression EXP Methamphetamine results in increased expression of DEAF1 mRNA CTD PMID:26307267 NCBI chr 7:141,297,176...141,338,869
Ensembl chr 7:141,297,180...141,327,690
JBrowse link
G Dennd5a DENN/MADD domain containing 5A increases expression EXP Methamphetamine results in increased expression of DENND5A mRNA CTD PMID:26307267 NCBI chr 7:109,893,780...109,960,470
Ensembl chr 7:109,893,780...109,960,470
JBrowse link
G Depdc1a DEP domain containing 1a decreases expression ISO Methamphetamine results in decreased expression of DEPDC1 mRNA CTD PMID:28341135 NCBI chr 3:159,495,414...159,529,955
Ensembl chr 3:159,495,433...159,529,955
JBrowse link
G Dgkb diacylglycerol kinase, beta decreases expression ISO Methamphetamine results in decreased expression of DGKB mRNA CTD PMID:32035215 NCBI chr12:37,880,169...38,634,239
Ensembl chr12:37,817,726...38,634,239
JBrowse link
G Dgkg diacylglycerol kinase, gamma increases expression EXP Methamphetamine results in increased expression of DGKG mRNA CTD PMID:26307267 NCBI chr16:22,466,568...22,657,302
Ensembl chr16:22,468,461...22,657,221
JBrowse link
G Dgkh diacylglycerol kinase, eta increases expression EXP Methamphetamine results in increased expression of DGKH mRNA CTD PMID:26307267 NCBI chr14:78,559,349...78,732,729
Ensembl chr14:78,558,750...78,732,776
JBrowse link
G Dgkz diacylglycerol kinase zeta increases expression EXP Methamphetamine results in increased expression of DGKZ mRNA CTD PMID:26307267 NCBI chr 2:91,932,822...91,976,443
Ensembl chr 2:91,932,824...91,975,864
JBrowse link
G Dhx16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 increases expression EXP Methamphetamine results in increased expression of DHX16 mRNA CTD PMID:26307267 NCBI chr17:35,879,764...35,892,670
Ensembl chr17:35,879,819...35,892,670
JBrowse link
G Diaph3 diaphanous related formin 3 decreases expression ISO Methamphetamine results in decreased expression of DIAPH3 mRNA CTD PMID:28341135 NCBI chr14:86,655,357...87,141,247
Ensembl chr14:86,655,367...87,141,235
JBrowse link
G Dicer1 dicer 1, ribonuclease type III increases methylation EXP Methamphetamine results in increased methylation of DICER1 promoter CTD PMID:26307267 NCBI chr12:104,687,740...104,751,968
Ensembl chr12:104,687,742...104,751,952
JBrowse link
G Dio2 deiodinase, iodothyronine, type II increases expression ISO Methamphetamine results in increased expression of DIO2 mRNA CTD PMID:19149911 NCBI chr12:90,724,552...90,739,038
Ensembl chr12:90,724,552...90,738,438
JBrowse link
G Dipk1a divergent protein kinase domain 1A decreases expression ISO Methamphetamine results in decreased expression of DIPK1A mRNA CTD PMID:19564919 NCBI chr 5:107,908,042...107,987,077
Ensembl chr 5:107,908,053...107,987,085
JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease increases expression ISO Methamphetamine results in increased expression of DIS3 mRNA CTD PMID:19564919 NCBI chr14:99,076,634...99,099,780
Ensembl chr14:99,075,206...99,099,770
JBrowse link
G Dis3l DIS3 like exosome 3'-5' exoribonuclease increases expression EXP Methamphetamine results in increased expression of DIS3L mRNA CTD PMID:26307267 NCBI chr 9:64,306,756...64,341,403
Ensembl chr 9:64,306,756...64,341,288
JBrowse link
G Dis3l2 DIS3 like 3'-5' exoribonuclease 2 increases expression ISO Methamphetamine results in increased expression of DIS3L2 mRNA CTD PMID:32035215 NCBI chr 1:86,701,924...87,050,097
Ensembl chr 1:86,703,808...87,050,095
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO Methamphetamine results in increased expression of DKK1 mRNA CTD PMID:25290377 NCBI chr19:30,545,876...30,549,496
Ensembl chr19:30,545,863...30,549,665
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) decreases expression ISO Methamphetamine results in decreased expression of DLAT protein CTD PMID:19826936 NCBI chr 9:50,634,633...50,659,780
Ensembl chr 9:50,634,633...50,659,780
JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression ISO Methamphetamine results in increased expression of DLD protein CTD PMID:19826936 NCBI chr12:31,331,562...31,351,471
Ensembl chr12:31,331,277...31,351,453
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
increases expression
ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of DLG4 protein] CTD PMID:33421459 NCBI chr11:70,017,203...70,045,535
Ensembl chr11:70,016,942...70,047,522
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression ISO Methamphetamine results in decreased expression of DLGAP5 mRNA CTD PMID:25290377 NCBI chr14:47,387,779...47,418,407
Ensembl chr14:47,387,779...47,418,407
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of DLST mRNA; Methamphetamine results in decreased expression of DLST protein
Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of DLST mRNA]
CTD PMID:19149911 PMID:19826936 NCBI chr12:85,110,822...85,134,091
Ensembl chr12:85,110,833...85,134,845
JBrowse link
G Dmd dystrophin, muscular dystrophy increases expression EXP Methamphetamine results in increased expression of DMD mRNA CTD PMID:26307267 NCBI chr  X:82,814,664...85,205,050
Ensembl chr  X:82,948,870...85,206,141
JBrowse link
G Dmkn dermokine increases expression
decreases expression
ISO Methamphetamine results in increased expression of DMKN mRNA
Methamphetamine results in decreased expression of DMKN mRNA
CTD PMID:19564919 PMID:32035215 NCBI chr 7:30,763,756...30,781,066
Ensembl chr 7:30,763,756...30,781,063
JBrowse link
G Dmpk dystrophia myotonica-protein kinase increases expression EXP Methamphetamine results in increased expression of DMPK mRNA CTD PMID:26307267 NCBI chr 7:19,083,646...19,093,821
Ensembl chr 7:19,083,849...19,093,821
JBrowse link
G Dmwd dystrophia myotonica-containing WD repeat motif increases expression EXP Methamphetamine results in increased expression of DMWD mRNA CTD PMID:26307267 NCBI chr 7:19,076,112...19,082,778
Ensembl chr 7:19,076,227...19,082,776
JBrowse link
G Dnaaf2 dynein, axonemal assembly factor 2 increases expression ISO Methamphetamine results in increased expression of DNAAF2 mRNA CTD PMID:19564919 NCBI chr12:69,189,087...69,200,083
Ensembl chr12:69,189,087...69,198,429
JBrowse link
G Dnah1 dynein, axonemal, heavy chain 1 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of DNAH1 mRNA
Methamphetamine results in decreased expression of DNAH1 mRNA
CTD PMID:19564919 NCBI chr14:31,260,375...31,325,891
Ensembl chr14:31,260,375...31,323,896
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJA1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJA1 mRNA] CTD PMID:19564919 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 increases expression ISO Methamphetamine results in increased expression of DNAJA4 mRNA CTD PMID:19564919 NCBI chr 9:54,698,848...54,716,317
Ensembl chr 9:54,698,873...54,716,315
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB1 mRNA] CTD PMID:19564919 NCBI chr 8:83,608,175...83,612,653
Ensembl chr 8:83,608,193...83,612,653
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB4 mRNA
Methamphetamine results in increased expression of DNAJB4 mRNA
CTD PMID:19564919 NCBI chr 3:152,181,580...152,210,432
Ensembl chr 3:152,178,511...152,210,302
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of DNAJB5 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB5 mRNA]
CTD PMID:19564919 NCBI chr 4:42,949,867...42,959,425
Ensembl chr 4:42,949,814...42,959,425
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of DNAJC3 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJC3 mRNA]
CTD PMID:19564919 NCBI chr14:118,937,932...118,981,702
Ensembl chr14:118,937,976...118,981,697
JBrowse link
G Dnal4 dynein, axonemal, light chain 4 decreases expression ISO Methamphetamine results in decreased expression of DNAL4 mRNA CTD PMID:19564919 NCBI chr15:79,761,449...79,774,467
Ensembl chr15:79,761,453...79,777,849
JBrowse link
G Dnase1 deoxyribonuclease I increases expression
decreases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of DNASE1 mRNA
Methamphetamine results in decreased expression of DNASE1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of DNASE1 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr16:4,036,958...4,040,024
Ensembl chr16:4,036,942...4,040,024
JBrowse link
G Dnm1 dynamin 1 increases expression EXP Methamphetamine results in increased expression of DNM1 mRNA CTD PMID:26307267 NCBI chr 2:32,308,471...32,353,349
Ensembl chr 2:32,308,471...32,353,338
JBrowse link
G Dnmt1 DNA methyltransferase (cytosine-5) 1 decreases expression
increases expression
ISO Methamphetamine results in decreased expression of DNMT1 mRNA
Methamphetamine results in increased expression of DNMT1 mRNA
CTD PMID:17254711 NCBI chr 9:20,907,206...20,959,888
Ensembl chr 9:20,907,209...20,959,888
JBrowse link
G Doc2g double C2, gamma increases expression EXP Methamphetamine results in increased expression of DOC2G mRNA CTD PMID:26307267 NCBI chr19:4,003,385...4,007,005
Ensembl chr19:4,003,313...4,007,005
JBrowse link
G Dock6 dedicator of cytokinesis 6 increases expression EXP Methamphetamine results in increased expression of DOCK6 mRNA CTD PMID:26307267 NCBI chr 9:21,800,180...21,852,718
Ensembl chr 9:21,799,860...21,852,635
JBrowse link
G Dok3 docking protein 3 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of DOK3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of DOK3 mRNA
CTD PMID:19564919 NCBI chr13:55,523,231...55,530,345
Ensembl chr13:55,523,231...55,529,296
JBrowse link
G Dolk dolichol kinase decreases expression ISO Methamphetamine results in decreased expression of DOLK mRNA CTD PMID:19564919 NCBI chr 2:30,284,229...30,286,354
Ensembl chr 2:30,284,231...30,286,334
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 affects expression ISO Methamphetamine affects the expression of DPYSL2 protein CTD PMID:19826936 NCBI chr14:66,802,864...66,911,041
Ensembl chr14:66,802,864...66,868,688
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression ISO Methamphetamine results in decreased expression of DPYSL3 protein CTD PMID:19826936 NCBI chr18:43,320,979...43,438,286
Ensembl chr18:43,320,984...43,438,286
JBrowse link
G Dpysl5 dihydropyrimidinase-like 5 increases expression ISO Methamphetamine results in increased expression of DPYSL5 protein CTD PMID:19826936 NCBI chr 5:30,711,564...30,799,369
Ensembl chr 5:30,711,564...30,799,375
JBrowse link
G Drd1 dopamine receptor D1 increases expression
decreases expression
affects activity
multiple interactions
increases response to substance
ISO
EXP
Methamphetamine results in increased expression of DRD1 protein
Methamphetamine results in decreased expression of DRD1 protein
Methamphetamine affects the activity of DRD1 protein
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD1 protein]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [SCH 23390 binds to DRD1 protein]
DRD1 protein results in increased susceptibility to Methamphetamine
[SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; bisphenol A promotes the reaction [DRD1 protein results in increased susceptibility to Methamphetamine]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]
CTD PMID:2891082 PMID:11126397 PMID:11701771 PMID:12617968 PMID:18363855 PMID:18489579 PMID:19444617 PMID:19733155 PMID:20340177 NCBI chr13:54,051,183...54,055,658
Ensembl chr13:54,051,183...54,055,705
JBrowse link
G Drd2 dopamine receptor D2 increases response to substance
decreases expression
multiple interactions
increases activity
affects activity
ISO
EXP
DRD2 gene polymorphism results in increased susceptibility to Methamphetamine
Methamphetamine results in decreased expression of DRD2 protein
[Sulpiride binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Methamphetamine; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]
Methamphetamine results in increased activity of DRD2 protein
Methamphetamine affects the activity of DRD2 protein
DRD2 gene results in increased susceptibility to Methamphetamine
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD2 protein]; [Aripiprazole binds to and results in increased activity of DRD2 protein] which results in increased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [Sulpiride binds to DRD2 protein]
CTD PMID:2891082 PMID:11126397 PMID:11729018 PMID:17327886 PMID:18363855 PMID:18489579 PMID:18555060 PMID:19046384 PMID:19940168 PMID:20340177 NCBI chr 9:49,340,360...49,408,177
Ensembl chr 9:49,340,627...49,408,177
JBrowse link
G Drd3 dopamine receptor D3 decreases expression
increases activity
ISO Methamphetamine results in decreased expression of DRD3 protein
Methamphetamine results in increased activity of DRD3 protein
CTD PMID:19046384 PMID:19940168 NCBI chr16:43,754,015...43,825,982
Ensembl chr16:43,754,026...43,822,932
JBrowse link
G Drd4 dopamine receptor D4 affects response to substance
multiple interactions
increases response to substance
ISO
EXP
DRD4 gene polymorphism affects the susceptibility to Methamphetamine
[NRA 0160 binds to and results in decreased activity of DRD4 protein] which results in decreased susceptibility to Methamphetamine
DRD4 gene polymorphism results in increased susceptibility to Methamphetamine
CTD PMID:10579464 PMID:15274053 PMID:19462300 NCBI chr 7:141,291,974...141,296,464
Ensembl chr 7:141,292,006...141,296,464
JBrowse link
G Dsp desmoplakin increases expression EXP Methamphetamine results in increased expression of DSP mRNA CTD PMID:26307267 NCBI chr13:38,151,294...38,198,577
Ensembl chr13:38,151,294...38,198,577
JBrowse link
G Dspp dentin sialophosphoprotein increases expression ISO Methamphetamine results in increased expression of DSPP mRNA CTD PMID:15644446 NCBI chr 5:104,170,703...104,180,127
Ensembl chr 5:104,170,712...104,180,127
JBrowse link
G Dst dystonin increases expression EXP Methamphetamine results in increased expression of DST mRNA CTD PMID:26307267 NCBI chr 1:33,907,888...34,308,662
Ensembl chr 1:33,908,225...34,308,661
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase decreases expression ISO Methamphetamine results in decreased expression of DTL mRNA CTD PMID:25290377 NCBI chr 1:191,537,356...191,575,544
Ensembl chr 1:191,537,356...191,575,544
JBrowse link
G Dtx3 deltex 3, E3 ubiquitin ligase increases expression
increases methylation
EXP Methamphetamine results in increased expression of DTX3 mRNA
Methamphetamine results in increased methylation of DTX3 promoter
CTD PMID:26307267 NCBI chr10:127,190,373...127,196,498
Ensembl chr10:127,190,378...127,195,728
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions
increases expression
ISO
EXP
[Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP1 mRNA; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA] CTD PMID:11701771 PMID:19564919 PMID:26307267 NCBI chr17:26,505,591...26,508,472
Ensembl chr17:26,505,590...26,562,128
JBrowse link
G Dusp11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) increases expression ISO Methamphetamine results in increased expression of DUSP11 mRNA CTD PMID:19564919 NCBI chr 6:85,942,268...85,961,732
Ensembl chr 6:85,942,268...85,961,667
JBrowse link
G Dusp14 dual specificity phosphatase 14 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP14 mRNA
Methamphetamine results in increased expression of DUSP14 mRNA
CTD PMID:19564919 NCBI chr11:84,048,033...84,069,256
Ensembl chr11:84,048,041...84,069,261
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO Methamphetamine results in increased expression of DUSP5 mRNA CTD PMID:19564919 NCBI chr19:53,529,145...53,541,809
Ensembl chr19:53,529,109...53,542,431
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions
increases expression
ISO [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA] CTD PMID:11701771 NCBI chr10:99,263,231...99,267,489
Ensembl chr10:99,263,231...99,267,489
JBrowse link
G Dut deoxyuridine triphosphatase increases expression ISO Methamphetamine results in increased expression of DUT mRNA CTD PMID:19149911 NCBI chr 2:125,247,248...125,259,049
Ensembl chr 2:125,247,190...125,258,608
JBrowse link
G Duxbl1 double homeobox B-like 1 decreases expression ISO Methamphetamine results in decreased expression of DUXBL1 mRNA CTD PMID:19564919 NCBI chr14:25,978,560...25,990,166
Ensembl chr14:26,257,962...26,269,436
Ensembl chr14:26,257,962...26,269,436
Ensembl chr14:26,257,962...26,269,436
JBrowse link
G Dydc2 DPY30 domain containing 2 increases expression ISO Methamphetamine results in increased expression of DYDC2 mRNA CTD PMID:28341135 NCBI chr14:41,048,957...41,073,037
Ensembl chr14:41,049,117...41,069,208
JBrowse link
G Dysf dysferlin increases expression EXP Methamphetamine results in increased expression of DYSF mRNA CTD PMID:26307267 NCBI chr 6:84,008,361...84,211,060
Ensembl chr 6:84,008,590...84,211,060
JBrowse link
G E130311K13Rik RIKEN cDNA E130311K13 gene decreases expression ISO Methamphetamine results in decreased expression of RGD1565059 mRNA CTD PMID:19564919 NCBI chr 3:63,914,682...63,929,507
Ensembl chr 3:63,914,684...63,929,472
JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 decreases expression EXP Methamphetamine results in decreased expression of EBI3 mRNA CTD PMID:26307267 NCBI chr17:55,952,623...55,957,022
Ensembl chr17:55,952,640...55,957,022
JBrowse link
G Echdc2 enoyl Coenzyme A hydratase domain containing 2 increases expression EXP Methamphetamine results in increased expression of ECHDC2 mRNA CTD PMID:26307267 NCBI chr 4:108,165,436...108,179,308
Ensembl chr 4:108,165,437...108,179,308
JBrowse link
G Echdc3 enoyl Coenzyme A hydratase domain containing 3 decreases expression EXP Methamphetamine results in decreased expression of ECHDC3 mRNA CTD PMID:26307267 NCBI chr 2:6,188,465...6,212,994
Ensembl chr 2:6,188,465...6,213,033
JBrowse link
G Ect2 ect2 oncogene decreases expression ISO Methamphetamine results in decreased expression of ECT2 mRNA CTD PMID:28341135 NCBI chr 3:27,097,222...27,154,253
Ensembl chr 3:27,097,222...27,153,878
JBrowse link
G Edc4 enhancer of mRNA decapping 4 increases expression EXP Methamphetamine results in increased expression of EDC4 mRNA CTD PMID:26307267 NCBI chr 8:105,880,873...105,893,225
Ensembl chr 8:105,880,881...105,894,908
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases methylation EXP Methamphetamine results in decreased methylation of EEF2K promoter CTD PMID:26307267 NCBI chr 7:120,842,642...120,907,219
Ensembl chr 7:120,842,831...120,907,450
JBrowse link
G Efnb1 ephrin B1 increases expression ISO Methamphetamine results in increased expression of EFNB1 mRNA CTD PMID:19564919 NCBI chr  X:99,136,061...99,149,022
Ensembl chr  X:99,136,130...99,148,991
JBrowse link
G Egfl7 EGF-like domain 7 multiple interactions
increases expression
decreases expression
ISO
EXP
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFL7 mRNA
Methamphetamine results in increased expression of EGFL7 mRNA
Methamphetamine results in decreased expression of EGFL7 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr 2:26,581,083...26,592,682
Ensembl chr 2:26,580,014...26,593,120
JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of EGFLAM mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFLAM mRNA
CTD PMID:19564919 NCBI chr15:7,206,120...7,398,744
Ensembl chr15:7,206,120...7,398,395
JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
ISO
EXP
CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]
Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]]
CTD PMID:11754491 PMID:15644446 PMID:19564919 PMID:20184921 PMID:20298714 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Egr2 early growth response 2 increases expression ISO Methamphetamine results in increased expression of EGR2 mRNA CTD PMID:15644446 PMID:19564919 NCBI chr10:67,534,469...67,542,188
Ensembl chr10:67,535,475...67,542,188
JBrowse link
G Egr4 early growth response 4 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of EGR4 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of EGR4 mRNA
CTD PMID:19564919 NCBI chr 6:85,511,121...85,513,589
Ensembl chr 6:85,511,121...85,513,589
JBrowse link
G Ehbp1l1 EH domain binding protein 1-like 1 increases expression EXP Methamphetamine results in increased expression of EHBP1L1 mRNA CTD PMID:26307267 NCBI chr19:5,707,369...5,726,576
Ensembl chr19:5,707,376...5,726,317
JBrowse link
G Ehmt2 euchromatic histone lysine N-methyltransferase 2 increases expression EXP Methamphetamine results in increased expression of EHMT2 mRNA CTD PMID:26307267 NCBI chr17:34,898,463...34,914,073
Ensembl chr17:34,898,469...34,914,052
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression ISO Methamphetamine results in increased expression of EIF1A mRNA CTD PMID:19564919 NCBI chr18:46,597,704...46,610,225
Ensembl chr18:46,597,701...46,616,456
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
increases phosphorylation
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of EIF2AK3 protein modified form
Methamphetamine results in increased phosphorylation of EIF2AK3 protein
CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]
CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of EIF2AK3 protein modified form]
CTD PMID:27323860 PMID:28070110 PMID:29705343 NCBI chr 6:70,844,484...70,905,241
Ensembl chr 6:70,844,515...70,905,245
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases phosphorylation
multiple interactions
ISO Methamphetamine results in increased phosphorylation of EIF2S1 protein
Melatonin inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein]
CTD PMID:28070110 NCBI chr12:78,862,072...78,887,010
Ensembl chr12:78,861,819...78,887,010
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Methamphetamine inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:19054297 NCBI chr 8:27,260,327...27,275,656
Ensembl chr 8:27,260,329...27,276,674
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 increases expression ISO Methamphetamine results in increased expression of EIF4G2 mRNA CTD PMID:10336889 NCBI chr 7:111,067,985...111,083,030
Ensembl chr 7:111,067,750...111,083,030
JBrowse link
G Elp1 elongator complex protein 1 increases expression ISO Methamphetamine results in increased expression of ELP1 mRNA CTD PMID:19564919 NCBI chr 4:56,746,547...56,802,569
Ensembl chr 4:56,749,680...56,802,331
JBrowse link
G Eml1 echinoderm microtubule associated protein like 1 increases expression ISO Methamphetamine results in increased expression of EML1 mRNA CTD PMID:32035215 NCBI chr12:108,371,002...108,539,576
Ensembl chr12:108,370,957...108,539,617
JBrowse link
G Eml2 echinoderm microtubule associated protein like 2 increases expression EXP Methamphetamine results in increased expression of EML2 mRNA CTD PMID:26307267 NCBI chr 7:19,176,421...19,206,482
Ensembl chr 7:19,176,421...19,206,482
JBrowse link
G Emsy EMSY, BRCA2-interacting transcriptional repressor increases expression EXP Methamphetamine results in increased expression of EMSY mRNA CTD PMID:26307267 NCBI chr 7:98,587,130...98,656,827
Ensembl chr 7:98,587,137...98,656,783
JBrowse link
G Eno1 enolase 1, alpha non-neuron decreases expression ISO Methamphetamine results in decreased expression of ENO1 protein CTD PMID:19826936 NCBI chr 4:150,236,708...150,248,879
Ensembl chr 4:150,236,721...150,248,879
JBrowse link
G Eno2 enolase 2, gamma neuronal increases expression ISO Methamphetamine results in increased expression of ENO2 protein CTD PMID:19826936 NCBI chr 6:124,760,053...124,769,673
Ensembl chr 6:124,760,053...124,769,673
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression EXP Methamphetamine results in decreased expression of ENPP1 mRNA CTD PMID:26307267 NCBI chr10:24,637,914...24,712,159
Ensembl chr10:24,637,914...24,712,159
JBrowse link
G Enpp6 ectonucleotide pyrophosphatase/phosphodiesterase 6 decreases expression ISO Methamphetamine results in decreased expression of ENPP6 mRNA CTD PMID:28619521 NCBI chr 8:46,939,197...47,096,762
Ensembl chr 8:46,986,887...47,096,762
JBrowse link
G Ep400 E1A binding protein p400 increases expression EXP Methamphetamine results in increased expression of EP400 mRNA CTD PMID:26307267 NCBI chr 5:110,664,373...110,770,927
Ensembl chr 5:110,664,373...110,770,717
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO Methamphetamine results in increased expression of EPAS1 mRNA CTD PMID:32035215 NCBI chr17:86,753,864...86,833,410
Ensembl chr17:86,753,700...86,833,410
JBrowse link
G Epb41l1 erythrocyte membrane protein band 4.1 like 1 decreases methylation EXP Methamphetamine results in decreased methylation of EPB41L1 promoter CTD PMID:26307267 NCBI chr 2:156,417,595...156,543,214
Ensembl chr 2:156,420,909...156,543,214
JBrowse link
G Epcam epithelial cell adhesion molecule decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of EPCAM mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EPCAM mRNA
CTD PMID:19564919 NCBI chr17:87,635,979...87,651,127
Ensembl chr17:87,635,979...87,651,129
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases expression
multiple interactions
increases methylation
EXP Methamphetamine results in increased expression of EPHX1 mRNA; Methamphetamine results in increased expression of EPHX1 protein
EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Methamphetamine promotes the reaction [PRKCD protein modified form binds to EPHX1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of EPHX1 protein]
Methamphetamine results in increased methylation of EPHX1 promoter
CTD PMID:26307267 PMID:31422080 NCBI chr 1:180,989,556...181,017,569
Ensembl chr 1:180,976,210...181,020,904
JBrowse link
G Epor erythropoietin receptor decreases expression ISO Methamphetamine results in decreased expression of EPOR mRNA CTD PMID:15644446 NCBI chr 9:21,958,897...21,963,576
Ensembl chr 9:21,958,897...21,963,506
JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 increases expression
multiple interactions
increases phosphorylation
ISO
EXP
Methamphetamine results in increased expression of ERN1 protein modified form
ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein]
Melatonin inhibits the reaction [Methamphetamine results in increased expression of ERN1 protein modified form]
CTD PMID:27323860 PMID:28070110 NCBI chr11:106,397,620...106,487,796
Ensembl chr11:106,394,650...106,487,852
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ERRFI1 mRNA
Methamphetamine results in increased expression of ERRFI1 mRNA
CTD PMID:19564919 NCBI chr 4:150,853,796...150,868,889
Ensembl chr 4:150,853,919...150,868,892
JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases response to substance ISO ESR1 gene polymorphism results in increased susceptibility to Methamphetamine CTD PMID:19386276 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Etl4 enhancer trap locus 4 increases expression EXP Methamphetamine results in increased expression of ETL4 mRNA CTD PMID:26307267 NCBI chr 2:19,910,207...20,810,535
Ensembl chr 2:19,909,780...20,810,713
JBrowse link
G Evc2 EvC ciliary complex subunit 2 increases expression ISO Methamphetamine results in increased expression of EVC2 mRNA CTD PMID:28341135 NCBI chr 5:37,338,478...37,425,055
Ensembl chr 5:37,338,499...37,425,055
JBrowse link
G Exoc7 exocyst complex component 7 decreases expression ISO Methamphetamine results in decreased expression of EXOC7 mRNA CTD PMID:19564919 NCBI chr11:116,287,997...116,306,750
Ensembl chr11:116,288,001...116,307,233
JBrowse link
G F11r F11 receptor multiple interactions
increases expression
ISO Luteolin inhibits the reaction [Methamphetamine results in increased expression of F11R mRNA] CTD PMID:32035215 NCBI chr 1:171,437,561...171,464,593
Ensembl chr 1:171,437,535...171,464,603
JBrowse link
G F3 coagulation factor III increases methylation EXP Methamphetamine results in increased methylation of F3 promoter CTD PMID:26307267 NCBI chr 3:121,723,537...121,735,052
Ensembl chr 3:121,723,537...121,735,048
JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of FAAH mRNA
Methamphetamine results in decreased expression of FAAH mRNA
CTD PMID:19564919 NCBI chr 4:115,996,668...116,018,837
Ensembl chr 4:115,967,145...116,017,926
JBrowse link
G Fabp3 fatty acid binding protein 3, muscle and heart affects response to substance
increases expression
EXP
ISO
FABP3 affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of FABP3 mRNA
CTD PMID:20181611 PMID:25290377 NCBI chr 4:130,308,738...130,315,463
Ensembl chr 4:130,308,595...130,315,463
JBrowse link
G Fabp7 fatty acid binding protein 7, brain affects expression ISO Methamphetamine affects the expression of FABP7 protein CTD PMID:17904249 NCBI chr10:57,784,923...57,788,450
Ensembl chr10:57,784,881...57,788,450
JBrowse link
G Fah fumarylacetoacetate hydrolase decreases expression ISO Methamphetamine results in decreased expression of FAH mRNA CTD PMID:19564919 NCBI chr 7:84,585,159...84,605,942
Ensembl chr 7:84,585,159...84,606,722
JBrowse link
G Fam110a family with sequence similarity 110, member A decreases expression ISO Methamphetamine results in decreased expression of FAM110A mRNA CTD PMID:19564919 NCBI chr 2:151,969,396...151,980,219
Ensembl chr 2:151,969,398...151,980,219
JBrowse link
G Fam126b family with sequence similarity 126, member B increases expression
multiple interactions
ISO Methamphetamine results in increased expression of FAM126B mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of FAM126B mRNA
CTD PMID:19564919 NCBI chr 1:58,522,806...58,586,333
Ensembl chr 1:58,522,806...58,586,323
JBrowse link
G Fam193a family with sequence homology 193, member A increases expression EXP Methamphetamine results in increased expression of FAM193A mRNA CTD PMID:26307267 NCBI chr 5:34,369,933...34,486,458
Ensembl chr 5:34,369,933...34,486,456
JBrowse link
G Fam193b family with sequence similarity 193, member B increases expression EXP Methamphetamine results in increased expression of FAM193B mRNA CTD PMID:26307267 NCBI chr13:55,539,316...55,571,120
Ensembl chr13:55,539,316...55,571,120
JBrowse link
G Fam71e1 family with sequence similarity 71, member E1 decreases expression ISO Methamphetamine results in decreased expression of FAM71E1 mRNA CTD PMID:19564919 NCBI chr 7:44,496,499...44,504,266
Ensembl chr 7:44,496,581...44,501,486
JBrowse link
G Fank1 fibronectin type 3 and ankyrin repeat domains 1 decreases expression ISO Methamphetamine results in decreased expression of FANK1 mRNA CTD PMID:19564919 NCBI chr 7:133,776,836...133,881,536
Ensembl chr 7:133,776,861...133,881,532
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) decreases expression
increases expression
ISO Methamphetamine results in decreased expression of FAS mRNA
Methamphetamine results in increased expression of FAS mRNA
CTD PMID:15644446 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) increases expression ISO Methamphetamine results in increased expression of FASLG mRNA; Methamphetamine results in increased expression of FASLG protein CTD PMID:15644446 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fastkd3 FAST kinase domains 3 decreases expression EXP Methamphetamine results in decreased expression of FASTKD3 mRNA CTD PMID:26307267 NCBI chr13:68,582,167...68,592,338
Ensembl chr13:68,582,234...68,592,338
JBrowse link
G Fblim1 filamin binding LIM protein 1 increases expression ISO Methamphetamine results in increased expression of FBLIM1 mRNA CTD PMID:19564919 NCBI chr 4:141,576,062...141,606,052
Ensembl chr 4:141,576,062...141,606,096
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 decreases expression ISO Methamphetamine results in decreased expression of FBXL4 mRNA CTD PMID:19564919 NCBI chr 4:22,357,526...22,434,091
Ensembl chr 4:22,357,543...22,434,091
JBrowse link
G Fbxo28 F-box protein 28 increases expression ISO Methamphetamine results in increased expression of FBXO28 mRNA CTD PMID:19564919 NCBI chr 1:182,313,102...182,341,606
Ensembl chr 1:182,313,102...182,341,629
JBrowse link
G Fbxo32 F-box protein 32 increases expression EXP Methamphetamine results in increased expression of FBXO32 mRNA CTD PMID:23933405 NCBI chr15:58,175,879...58,214,892
Ensembl chr15:58,175,879...58,214,932
JBrowse link
G Fbxo33 F-box protein 33 increases expression ISO Methamphetamine results in increased expression of FBXO33 mRNA CTD PMID:19564919 NCBI chr12:59,200,655...59,221,961
Ensembl chr12:59,200,655...59,219,725
JBrowse link
G Fcgbp Fc fragment of IgG binding protein decreases expression EXP Methamphetamine results in decreased expression of FCGBP mRNA CTD PMID:26307267 NCBI chr 7:28,071,236...28,120,864
Ensembl chr 7:28,071,236...28,120,862
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Methamphetamine results in increased expression of FGF2 mRNA CTD PMID:19564919 NCBI chr 3:37,348,477...37,410,106
Ensembl chr 3:37,348,346...37,410,108
JBrowse link
G Fgf4 fibroblast growth factor 4 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of FGF4 mRNA
Methamphetamine results in increased expression of FGF4 mRNA
CTD PMID:19564919 NCBI chr 7:144,861,386...144,865,245
Ensembl chr 7:144,847,367...144,865,243
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression EXP Methamphetamine results in increased expression of FGFR3 mRNA CTD PMID:26307267 NCBI chr 5:33,721,724...33,737,068
Ensembl chr 5:33,721,674...33,737,068
JBrowse link
G Fhit fragile histidine triad gene affects response to substance ISO FHIT gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr14:9,550,092...11,162,061
Ensembl chr14:9,550,092...11,162,035
JBrowse link
G Fjx1 four jointed box 1 decreases expression ISO Methamphetamine results in decreased expression of FJX1 mRNA CTD PMID:19564919 NCBI chr 2:102,449,366...102,451,792
Ensembl chr 2:102,449,366...102,452,499
JBrowse link
G Fkbp15 FK506 binding protein 15 affects response to substance ISO FKBP15 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 4:62,300,342...62,360,596
Ensembl chr 4:62,300,342...62,360,548
JBrowse link
G Fkbp4 FK506 binding protein 4 increases expression ISO Methamphetamine results in increased expression of FKBP4 mRNA CTD PMID:19149911 NCBI chr 6:128,430,103...128,438,656
Ensembl chr 6:128,429,735...128,438,677
JBrowse link
G Flna filamin, alpha increases expression EXP Methamphetamine results in increased expression of FLNA mRNA CTD PMID:26307267 NCBI chr  X:74,223,461...74,249,854
Ensembl chr  X:74,223,461...74,249,820
JBrowse link
G Flnb filamin, beta increases expression EXP Methamphetamine results in increased expression of FLNB mRNA CTD PMID:26307267 NCBI chr14:7,817,921...7,951,588
Ensembl chr14:7,817,957...7,951,588
JBrowse link
G Flnc filamin C, gamma increases expression EXP Methamphetamine results in increased expression of FLNC mRNA CTD PMID:26307267 NCBI chr 6:29,433,153...29,461,889
Ensembl chr 6:29,433,256...29,461,883
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 increases expression EXP
ISO
Methamphetamine results in increased expression of FLT1 mRNA CTD PMID:26307267 PMID:32035215 NCBI chr 5:147,561,604...147,726,438
Ensembl chr 5:147,561,604...147,726,011
JBrowse link
G Fmo2 flavin containing monooxygenase 2 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of FMO2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of FMO2 mRNA
CTD PMID:19564919 NCBI chr 1:162,874,317...162,898,758
Ensembl chr 1:162,874,317...162,898,726
JBrowse link
G Fmo3 flavin containing monooxygenase 3 increases metabolic processing ISO FMO3 protein results in increased metabolism of Methamphetamine CTD PMID:27320963 NCBI chr 1:162,953,799...162,984,528
Ensembl chr 1:162,953,800...162,984,528
JBrowse link
G Fn1 fibronectin 1 increases expression EXP Methamphetamine results in increased expression of FN1 mRNA CTD PMID:12766323 NCBI chr 1:71,585,473...71,653,280
Ensembl chr 1:71,585,520...71,653,200
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
affects response to substance
EXP
ISO
Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]; FOS protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Idazoxan inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]]; Lidocaine inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]]
Methamphetamine results in increased expression of FOS mRNA; Methamphetamine results in increased expression of FOS protein
[Methamphetamine co-treated with SCH 23390] results in increased expression of FOS mRNA; Carbamazepine inhibits the reaction [Methamphetamine results in increased expression of FOS protein]; Oxytocin inhibits the reaction [Methamphetamine results in increased expression of FOS protein]
Methamphetamine results in increased expression of FOS; Methamphetamine results in increased expression of FOS protein
FOS mRNA affects the susceptibility to Methamphetamine; FOS protein affects the susceptibility to Methamphetamine
CTD PMID:10559418 PMID:10731628 PMID:11754491 PMID:12050851 PMID:19564919 PMID:19689456 PMID:20731630 PMID:20950675 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Fosl1 fos-like antigen 1 increases expression ISO Methamphetamine results in increased expression of FOSL1 mRNA CTD PMID:19564919 NCBI chr19:5,447,698...5,455,938
Ensembl chr19:5,447,547...5,455,946
JBrowse link
G Foxe1 forkhead box E1 increases expression ISO Methamphetamine results in increased expression of FOXE1 mRNA; Methamphetamine results in increased expression of FOXE1 protein CTD PMID:28341135 NCBI chr 4:46,343,644...46,345,774
Ensembl chr 4:46,343,609...46,346,412
JBrowse link
G Fst follistatin decreases expression ISO Methamphetamine results in decreased expression of FST mRNA CTD PMID:28619521 NCBI chr13:114,452,262...114,458,989
Ensembl chr13:114,452,290...114,458,951
JBrowse link
G Ftcd formiminotransferase cyclodeaminase multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of FTCD mRNA
Methamphetamine results in increased expression of FTCD mRNA
CTD PMID:19564919 NCBI chr10:76,575,648...76,590,338
Ensembl chr10:76,575,648...76,590,338
JBrowse link
G Fuz fuzzy planar cell polarity protein increases expression EXP Methamphetamine results in increased expression of FUZ mRNA CTD PMID:26307267 NCBI chr 7:44,894,305...44,900,624
Ensembl chr 7:44,896,079...44,902,631
JBrowse link
G Fyn Fyn proto-oncogene increases expression EXP Methamphetamine results in increased expression of FYN mRNA CTD PMID:26307267 NCBI chr10:39,369,743...39,565,381
Ensembl chr10:39,368,855...39,565,381
JBrowse link
G Gabarapl2 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2 increases methylation EXP Methamphetamine results in increased methylation of GABARAPL2 promoter CTD PMID:26307267 NCBI chr 8:111,940,703...111,952,915
Ensembl chr 8:111,940,703...111,953,612
JBrowse link
G Gabbr2 gamma-aminobutyric acid (GABA) B receptor, 2 multiple interactions ISO Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] CTD PMID:21729720 NCBI chr 4:46,662,318...46,991,714
Ensembl chr 4:46,662,305...46,991,873
JBrowse link
G Gabpa GA repeat binding protein, alpha increases expression
multiple interactions
ISO Methamphetamine results in increased expression of GABPA mRNA
Lithium inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA]
CTD PMID:19149911 NCBI chr16:84,834,891...84,863,783
Ensembl chr16:84,834,925...84,863,779
JBrowse link
G Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 multiple interactions ISO Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] CTD PMID:21729720 NCBI chr11:42,130,939...42,183,066
Ensembl chr11:42,130,939...42,182,930
JBrowse link
G Gabrg2 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 increases response to substance
multiple interactions
ISO GABRG2 gene results in increased susceptibility to Methamphetamine
Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]
CTD PMID:15772696 PMID:21729720 NCBI chr11:41,910,190...42,000,857
Ensembl chr11:41,910,203...42,000,857
JBrowse link
G Gabrg3 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 increases expression ISO Methamphetamine results in increased expression of GABRG3 mRNA CTD PMID:15644446 NCBI chr 7:56,716,463...57,387,215
Ensembl chr 7:56,716,465...57,387,188
JBrowse link
G Gabrr3 gamma-aminobutyric acid (GABA) receptor, rho 3 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of GABRR3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GABRR3 mRNA
CTD PMID:19564919 NCBI chr16:59,407,382...59,461,739
Ensembl chr16:59,407,332...59,464,504
JBrowse link
G Gad2 glutamic acid decarboxylase 2 increases expression ISO Methamphetamine results in increased expression of GAD2 mRNA CTD PMID:15601951 NCBI chr 2:22,621,015...22,693,877
Ensembl chr 2:22,622,205...22,693,874
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45B mRNA
Methamphetamine results in increased expression of GADD45B mRNA
CTD PMID:19564919 NCBI chr10:80,930,091...80,932,204
Ensembl chr10:80,930,073...80,932,204
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma increases expression
multiple interactions
ISO Methamphetamine results in increased expression of GADD45G mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45G mRNA
CTD PMID:19564919 NCBI chr13:51,846,675...51,848,475
Ensembl chr13:51,846,678...51,848,468
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression
decreases expression
ISO Methamphetamine results in increased expression of GAL mRNA
Methamphetamine results in decreased expression of GAL mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr19:3,409,915...3,414,544
Ensembl chr19:3,409,915...3,414,544
JBrowse link
G Galk1 galactokinase 1 decreases expression ISO Methamphetamine results in decreased expression of GALK1 mRNA CTD PMID:19564919 NCBI chr11:116,008,357...116,012,719
Ensembl chr11:116,008,457...116,012,719
JBrowse link
G Galntl6 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 decreases expression EXP Methamphetamine results in decreased expression of GALNTL6 mRNA CTD PMID:26307267 NCBI chr 8:57,772,489...58,912,531
Ensembl chr 8:57,774,052...58,912,640
JBrowse link
G Galt galactose-1-phosphate uridyl transferase increases expression EXP Methamphetamine results in increased expression of GALT mRNA CTD PMID:26307267 NCBI chr 4:41,755,517...41,759,243
Ensembl chr 4:41,755,228...41,758,695
JBrowse link
G Gap43 growth associated protein 43 multiple interactions
decreases expression
ISO Melatonin inhibits the reaction [Methamphetamine results in decreased expression of GAP43 protein] CTD PMID:19409439 NCBI chr16:42,248,552...42,340,651
Ensembl chr16:42,248,442...42,340,651
JBrowse link
G Gas5 growth arrest specific 5 increases expression ISO Methamphetamine results in increased expression of GAS5 mRNA CTD PMID:28619521 NCBI chr 1:161,034,601...161,038,539
Ensembl chr 1:161,034,422...161,038,539
JBrowse link
G Gas8 growth arrest specific 8 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of GAS8 mRNA
Methamphetamine results in decreased expression of GAS8 mRNA
CTD PMID:19564919 NCBI chr 8:123,518,835...123,536,657
Ensembl chr 8:123,518,834...123,536,650
JBrowse link
G Gatad2b GATA zinc finger domain containing 2B increases expression ISO Methamphetamine results in increased expression of GATAD2B mRNA CTD PMID:19564919 NCBI chr 3:90,293,181...90,363,405
Ensembl chr 3:90,293,178...90,363,407
JBrowse link
G Gbf1 golgi-specific brefeldin A-resistance factor 1 increases expression EXP Methamphetamine results in increased expression of GBF1 mRNA CTD PMID:26307267 NCBI chr19:46,152,509...46,286,510
Ensembl chr19:46,152,509...46,286,510
JBrowse link
G Gbgt1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 increases expression ISO Methamphetamine results in increased expression of GBGT1 mRNA CTD PMID:28341135 NCBI chr 2:28,479,354...28,506,030
Ensembl chr 2:28,496,891...28,505,415
JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression ISO Methamphetamine results in increased expression of GCH1 mRNA CTD PMID:19564919 NCBI chr14:47,153,895...47,189,413
Ensembl chr14:47,153,895...47,189,413
JBrowse link
G Gcsh glycine cleavage system protein H (aminomethyl carrier) decreases expression ISO Methamphetamine results in decreased expression of GCSH mRNA CTD PMID:19149911 NCBI chr 8:116,981,967...116,993,498
Ensembl chr 8:116,981,810...116,993,537
JBrowse link
G Gda guanine deaminase decreases expression ISO Methamphetamine results in decreased expression of GDA protein CTD PMID:19826936 NCBI chr19:21,391,307...21,472,661
Ensembl chr19:21,391,307...21,473,445
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of GDF15 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr 8:70,629,393...70,632,470
Ensembl chr 8:70,629,393...70,632,456
JBrowse link
G Gdi1 guanosine diphosphate (GDP) dissociation inhibitor 1 decreases expression ISO Methamphetamine results in decreased expression of GDI1 protein CTD PMID:19826936 NCBI chr  X:74,305,012...74,311,867
Ensembl chr  X:74,304,998...74,311,862
JBrowse link
G Gdnf glial cell line derived neurotrophic factor decreases response to substance EXP GDNF protein results in decreased susceptibility to Methamphetamine CTD PMID:17356005 NCBI chr15:7,810,048...7,837,580
Ensembl chr15:7,810,846...7,837,575
JBrowse link
G Gem GTP binding protein (gene overexpressed in skeletal muscle) multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] affects the expression of GEM mRNA
Methamphetamine results in increased expression of GEM mRNA
CTD PMID:19564919 NCBI chr 4:11,704,447...11,714,993
Ensembl chr 4:11,704,457...11,714,752
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
affects expression
EXP
ISO
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [[PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein]; [PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein; isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; Raclopride inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP mRNA]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; TAAR1 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]
Methamphetamine results in increased expression of GFAP mRNA; Methamphetamine results in increased expression of GFAP protein
Methamphetamine affects the expression of GFAP protein
CTD PMID:9427479 PMID:9634552 PMID:9739098 PMID:10773198 PMID:12766323 PMID:15337264 PMID:15644446 PMID:16088948 PMID:17262233 PMID:19834288 PMID:21867746 PMID:24072398 PMID:26283213 PMID:28919515 PMID:29467000 PMID:32278788 NCBI chr11:102,887,336...102,897,200
Ensembl chr11:102,887,336...102,900,912
JBrowse link
G Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 increases expression ISO Methamphetamine results in increased expression of GFRA2 mRNA CTD PMID:15644446 NCBI chr14:70,890,107...70,979,840
Ensembl chr14:70,890,120...70,979,838
JBrowse link
G Gfra4 glial cell line derived neurotrophic factor family receptor alpha 4 decreases expression
multiple interactions