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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:secondary amine
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Accession:CHEBI:32863 term browser browse the term
Definition:A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups.
Synonyms:exact_synonym: secondary amines
 related_synonym: Formula=HNR2;   R2NH;   SMILES=[H]N([*])[*];   sekundaeres Amin
 alt_id: CHEBI:26618;   CHEBI:9078
 xref: KEGG:C02324
 cyclic_relationship: is_conjugate_base_of CHEBI:137419


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bisoprolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases transport
multiple interactions
EXP ABCB1 protein results in increased transport of Bisoprolol
Bisoprolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; valspodar inhibits the reaction [ABCB1 protein results in increased transport of Bisoprolol]
CTD PMID:16671962 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ADRB1 adrenoceptor beta 1 decreases activity
increases expression
multiple interactions
affects binding
EXP
ISO
Bisoprolol results in decreased activity of ADRB1 protein
Bisoprolol results in increased expression of ADRB1 mRNA
[Bisoprolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; Bisoprolol binds to and results in decreased activity of ADRB1 protein; Bisoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Bisoprolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB1 protein]
Bisoprolol binds to ADRB1 protein
CTD PMID:1389726 PMID:2897299 PMID:10372227 PMID:11562432 PMID:12535855 PMID:14730417 PMID:15060759 PMID:17200720 PMID:20668454 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G ADRB2 adrenoceptor beta 2 multiple interactions
increases expression
EXP
ISO
[Bisoprolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Bisoprolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; Bisoprolol binds to and results in decreased activity of ADRB2 protein; Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB2 protein]
Bisoprolol results in increased expression of ADRB2 mRNA
CTD PMID:14730417 PMID:17925438 PMID:20668454 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
JBrowse link
G ADRB3 adrenoceptor beta 3 multiple interactions EXP Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB3 protein] CTD PMID:14730417 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599
JBrowse link
G CCL2 C-C motif chemokine ligand 2 decreases expression EXP Bisoprolol results in decreased expression of CCL2 protein CTD PMID:19840533 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G GNAS GNAS complex locus increases expression ISO Bisoprolol results in increased expression of GNAS mRNA CTD PMID:20668454 NCBI chr20:58,839,681...58,911,192
Ensembl chr20:58,839,718...58,911,192
JBrowse link
G IL10 interleukin 10 increases expression EXP Bisoprolol results in increased expression of IL10 protein CTD PMID:19840533 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1B interleukin 1 beta decreases expression EXP Bisoprolol results in decreased expression of IL1B protein CTD PMID:19840533 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 decreases expression EXP Bisoprolol results in decreased expression of IL6 protein CTD PMID:19840533 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INS insulin multiple interactions EXP Bisoprolol inhibits the reaction [Terbutaline results in increased expression of INS protein] CTD PMID:12795776 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G PRKCA protein kinase C alpha decreases expression ISO Bisoprolol results in decreased expression of PRKCA protein CTD PMID:20668454 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
JBrowse link
G PRKCD protein kinase C delta decreases expression ISO Bisoprolol results in decreased expression of PRKCD protein CTD PMID:20668454 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G SLC22A1 solute carrier family 22 member 1 multiple interactions EXP Bisoprolol inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 6:160,121,808...160,160,590
Ensembl chr 6:160,121,815...160,158,718
JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Bisoprolol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:19740083 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
G TNF tumor necrosis factor decreases expression EXP Bisoprolol results in decreased expression of TNF protein CTD PMID:19840533 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
brimonidine tartrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA2A adrenoceptor alpha 2A multiple interactions EXP
ISO
Brimonidine Tartrate inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]; Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]; Prazosin inhibits the reaction [Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]]; Yohimbine inhibits the reaction [Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]] CTD PMID:8397342 PMID:10742289 PMID:12208771 PMID:12598592 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
JBrowse link
G AGT angiotensinogen multiple interactions ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions ISO Brimonidine Tartrate inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CREB1 cAMP responsive element binding protein 1 increases phosphorylation ISO Brimonidine Tartrate results in increased phosphorylation of CREB1 protein CTD PMID:17680988 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G PRKCA protein kinase C alpha affects localization
multiple interactions
ISO Brimonidine Tartrate affects the localization of PRKCA protein
Nitric Oxide deficiency promotes the reaction [Brimonidine Tartrate affects the localization of PRKCA protein]
CTD PMID:12388232 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
JBrowse link
G PRKCD protein kinase C delta affects localization
multiple interactions
ISO Brimonidine Tartrate affects the localization of PRKCD protein
Nitric Oxide deficiency inhibits the reaction [Brimonidine Tartrate affects the localization of PRKCD protein]
CTD PMID:12388232 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G RHOA ras homolog family member A multiple interactions ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G SLC22A2 solute carrier family 22 member 2 multiple interactions EXP Brimonidine Tartrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
JBrowse link
diethylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HRH3 histamine receptor H3 multiple interactions ISO
EXP
diethylamine binds to and results in decreased activity of HRH3 protein CTD PMID:17169555 NCBI chr20:62,213,845...62,220,278
Ensembl chr20:62,214,960...62,220,278
JBrowse link
G IFNG interferon gamma multiple interactions ISO [diethylamine co-treated with Sodium Dodecyl Sulfate] results in increased expression of IFNG protein CTD PMID:12062936 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL18 interleukin 18 increases activity ISO diethylamine results in increased activity of IL18 protein CTD PMID:15840424 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1A interleukin 1 alpha increases activity ISO diethylamine results in increased activity of IL1A protein CTD PMID:15840424 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL4 interleukin 4 multiple interactions ISO [diethylamine co-treated with Sodium Dodecyl Sulfate] results in increased expression of IL4 protein CTD PMID:12062936 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
dimethylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DEK DEK proto-oncogene increases secretion EXP DEK protein results in increased secretion of dimethylamine CTD PMID:28558019 NCBI chr 6:18,223,860...18,264,541
Ensembl chr 6:18,223,860...18,264,548
JBrowse link
G HRH3 histamine receptor H3 multiple interactions EXP
ISO
dimethylamine binds to and results in decreased activity of HRH3 protein CTD PMID:17169555 NCBI chr20:62,213,845...62,220,278
Ensembl chr20:62,214,960...62,220,278
JBrowse link
dobutamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB11 ATP binding cassette subfamily B member 11 decreases activity EXP Dobutamine results in decreased activity of ABCB11 protein CTD PMID:28437613 NCBI chr 2:168,915,468...169,031,396
Ensembl chr 2:168,915,498...169,031,324
JBrowse link
G ADCY6 adenylate cyclase 6 affects response to substance ISO ADCY6 protein affects the susceptibility to Dobutamine CTD PMID:12393090 NCBI chr12:48,766,194...48,789,089
Ensembl chr12:48,766,194...48,789,089
JBrowse link
G ADRA2A adrenoceptor alpha 2A multiple interactions EXP Dobutamine binds to and results in increased activity of ADRA2A protein CTD PMID:16024912 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907
JBrowse link
G ADRB1 adrenoceptor beta 1 affects response to substance
multiple interactions
EXP
ISO
ADRB1 gene affects the susceptibility to Dobutamine; ADRB1 gene polymorphism affects the susceptibility to Dobutamine; ADRB1 protein polymorphism affects the susceptibility to Dobutamine
[Dobutamine co-treated with ICI 118551] results in decreased expression of ADRB1 mRNA; [Dobutamine co-treated with ICI 118551] results in decreased expression of ADRB1 protein; Dobutamine binds to and results in increased activity of ADRB1 protein; Dobutamine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Oxygen deficiency results in increased susceptibility to [Dobutamine binds to and results in increased activity of ADRB1 protein]
ADRB1 gene polymorphism affects the susceptibility to [Dobutamine co-treated with Metoprolol]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Dobutamine binds to and results in increased activity of ADRB1 protein; Dobutamine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of and results in increased uptake of EGFR protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]
CTD PMID:8096834 PMID:10192281 PMID:11753577 PMID:14502278 PMID:15564877 PMID:16024912 PMID:18787115 PMID:19719783 PMID:20821015 PMID:21311897 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G ADRB2 adrenoceptor beta 2 affects response to substance EXP ADRB2 gene polymorphism affects the susceptibility to Dobutamine CTD PMID:17094270 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
JBrowse link
G ADRB3 adrenoceptor beta 3 multiple interactions ISO [Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 mRNA; [Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 protein CTD PMID:19719783 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599
JBrowse link
G AHSG alpha 2-HS glycoprotein affects response to substance ISO AHSG protein affects the susceptibility to Dobutamine CTD PMID:16177000 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318
JBrowse link
G AKT1 AKT serine/threonine kinase 1 affects response to substance
multiple interactions
EXP
ISO
AKT1 protein affects the susceptibility to Dobutamine
Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein]
CTD PMID:16094411 PMID:16339297 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G AKT2 AKT serine/threonine kinase 2 multiple interactions ISO Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT2 protein] CTD PMID:16339297 NCBI chr19:40,230,317...40,285,531
Ensembl chr19:40,230,317...40,285,536
JBrowse link
G AKT3 AKT serine/threonine kinase 3 multiple interactions ISO Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT3 protein] CTD PMID:16339297 NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079
JBrowse link
G ARRB1 arrestin beta 1 multiple interactions EXP ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]] CTD PMID:18787115 NCBI chr11:75,260,122...75,351,662
Ensembl chr11:75,260,122...75,351,705
JBrowse link
G ARRB2 arrestin beta 2 multiple interactions EXP ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]] CTD PMID:18787115 NCBI chr17:4,710,619...4,721,500
Ensembl chr17:4,710,596...4,721,499
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression ISO Dobutamine results in increased expression of BAX protein CTD PMID:15052282 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression ISO Dobutamine results in decreased expression of BCL2 protein CTD PMID:15052282 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BNIP1 BCL2 interacting protein 1 increases expression ISO Dobutamine results in increased expression of BNIP1 protein CTD PMID:15052282 NCBI chr 5:173,144,447...173,164,387
Ensembl chr 5:173,144,442...173,164,387
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions EXP Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] CTD PMID:12818967 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions EXP Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 protein] CTD PMID:12818968 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CLU clusterin increases expression ISO Dobutamine results in increased expression of CLU protein CTD PMID:15052282 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G COMT catechol-O-methyltransferase increases methylation
increases expression
EXP
ISO
COMT protein results in increased methylation of Dobutamine
Dobutamine results in increased expression of COMT mRNA
CTD PMID:11160877 PMID:12423672 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A increases expression ISO Dobutamine results in increased expression of CPT1A mRNA; Dobutamine results in increased expression of CPT1A protein CTD PMID:8479178 NCBI chr11:68,754,620...68,844,410
Ensembl chr11:68,754,620...68,844,410
JBrowse link
G CREM cAMP responsive element modulator affects response to substance ISO CREM protein affects the susceptibility to Dobutamine CTD PMID:12475904 NCBI chr10:35,126,841...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CTF1 cardiotrophin 1 affects response to substance ISO CTF1 protein affects the susceptibility to Dobutamine CTD PMID:17150369 NCBI chr16:30,895,824...30,903,560
Ensembl chr16:30,896,614...30,903,547
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA] CTD PMID:11605937 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases expression
EXP Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]; Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 protein]
Dobutamine results in increased expression of CXCL8 mRNA
CTD PMID:12818968 PMID:15502056 PMID:32816093 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G DBH dopamine beta-hydroxylase affects response to substance ISO DBH protein affects the susceptibility to Dobutamine CTD PMID:10338466 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G DMD dystrophin increases response to substance ISO DMD gene mutant form results in increased susceptibility to Dobutamine CTD PMID:17440445 NCBI chr  X:31,119,219...33,339,460
Ensembl chr  X:31,097,677...33,339,609
JBrowse link
G EGFR epidermal growth factor receptor decreases response to substance
multiple interactions
ISO
EXP
EGFR gene mutant form results in decreased susceptibility to Dobutamine
AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of and results in increased uptake of EGFR protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]
CTD PMID:18599591 PMID:18787115 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP Dobutamine binds to and results in increased activity of ESR1 protein CTD PMID:24928891 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP Dobutamine results in increased expression of F3 protein CTD PMID:16286589 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FGF2 fibroblast growth factor 2 affects response to substance EXP
ISO
FGF2 protein affects the susceptibility to Dobutamine CTD PMID:10491406 PMID:14583313 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]; Metoprolol inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase increases activity ISO Dobutamine results in increased activity of G6PD protein CTD PMID:1978808 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,531,391...154,547,572
JBrowse link
G GH1 growth hormone 1 multiple interactions ISO GH1 protein promotes the reaction [Dobutamine results in increased metabolism of Lipids] CTD PMID:14981226 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GK glycerol kinase increases activity ISO Dobutamine results in increased activity of GK protein CTD PMID:12736183 NCBI chr  X:30,653,348...30,731,462
Ensembl chr  X:30,653,359...30,731,462
JBrowse link
G GNAS GNAS complex locus increases response to substance EXP GNAS gene SNP results in increased susceptibility to Dobutamine CTD PMID:19542315 NCBI chr20:58,839,681...58,911,192
Ensembl chr20:58,839,718...58,911,192
JBrowse link
G GSK3B glycogen synthase kinase 3 beta affects response to substance ISO GSK3B gene mutant form affects the susceptibility to Dobutamine CTD PMID:17901358 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G HBEGF heparin binding EGF like growth factor multiple interactions EXP HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]] CTD PMID:18787115 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression
ISO esmolol inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]; Metoprolol inhibits the reaction [Dobutamine results in increased expression of HMOX1 mRNA]; Metoprolol inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased expression of HMOX1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]
Dobutamine results in increased expression of HMOX1 mRNA; Dobutamine results in increased expression of HMOX1 protein
CTD PMID:15179140 PMID:16627864 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G IGF1 insulin like growth factor 1 increases response to substance ISO IGF1 protein results in increased susceptibility to Dobutamine CTD PMID:17184500 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IL10 interleukin 10 multiple interactions EXP
ISO
Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]
Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
CTD PMID:11605937 PMID:15502056 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1B interleukin 1 beta increases expression
decreases expression
ISO
EXP
Dobutamine results in increased expression of IL1B mRNA
Dobutamine results in decreased expression of IL1B mRNA
CTD PMID:9387890 PMID:32816093 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions
decreases expression
EXP
ISO
Dobutamine results in increased expression of IL6 protein
Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
Dobutamine results in decreased expression of IL6 mRNA
CTD PMID:11605937 PMID:12423672 PMID:16286589 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ITGB1 integrin subunit beta 1 affects response to substance ISO ITGB1 protein affects the susceptibility to Dobutamine CTD PMID:11884376 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]; Metoprolol inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]; Metoprolol inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 decreases activity EXP Dobutamine results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 7:150,944,956...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 multiple interactions
affects response to substance
ISO KCNJ11 protein affects the reaction [[Manganese co-treated with Dobutamine] results in increased abundance of Calcium]
KCNJ11 protein affects the susceptibility to Dobutamine
CTD PMID:17189350 NCBI chr11:17,385,246...17,389,346
Ensembl chr11:17,365,172...17,389,331
JBrowse link
G KLK1 kallikrein 1 affects response to substance EXP KLK1 protein affects the susceptibility to Dobutamine CTD PMID:12411458 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
JBrowse link
G LEP leptin decreases secretion
decreases expression
EXP
ISO
Dobutamine results in decreased secretion of LEP protein
Dobutamine results in decreased expression of LEP mRNA; Dobutamine results in decreased expression of LEP protein
CTD PMID:9002984 PMID:11022189 NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LEPR leptin receptor affects response to substance ISO LEPR protein affects the susceptibility to Dobutamine CTD PMID:20175764 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
[Dobutamine co-treated with ICI 118551] results in increased activity of MAPK1 protein
AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]
Dobutamine results in increased phosphorylation of MAPK1 protein
CTD PMID:16760913 PMID:18787115 PMID:19719783 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
[Dobutamine co-treated with ICI 118551] results in increased activity of MAPK3 protein
AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]
Dobutamine results in increased phosphorylation of MAPK3 protein
CTD PMID:16760913 PMID:18787115 PMID:19719783 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO [Dobutamine co-treated with ICI 118551] results in increased activity of MAPK9 protein CTD PMID:19719783 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MB myoglobin affects response to substance ISO MB protein affects the susceptibility to Dobutamine CTD PMID:10468637 NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions EXP Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] CTD PMID:15502056 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,513...35,404,749
JBrowse link
G NOS1 nitric oxide synthase 1 affects response to substance ISO NOS1 protein affects the susceptibility to Dobutamine CTD PMID:16344403 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS2 nitric oxide synthase 2 affects response to substance EXP
ISO
NOS2 protein affects the susceptibility to Dobutamine CTD PMID:9396439 PMID:11489778 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 increases activity EXP Dobutamine results in increased activity of NR1H4 protein CTD PMID:22414727 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
G PHGDH phosphoglycerate dehydrogenase increases expression ISO Dobutamine results in increased expression of PHGDH mRNA CTD PMID:12423672 NCBI chr 1:119,711,934...119,744,218
Ensembl chr 1:119,648,411...119,744,218
JBrowse link
G PLN phospholamban affects response to substance EXP PLN protein affects the susceptibility to Dobutamine CTD PMID:14991071 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha affects response to substance ISO PPP2CA protein affects the susceptibility to Dobutamine CTD PMID:15247211 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,332...134,226,073
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of PRKACA protein] CTD PMID:16339297 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
JBrowse link
G PRKCE protein kinase C epsilon affects response to substance ISO PRKCE protein affects the susceptibility to Dobutamine CTD PMID:15242976 NCBI chr 2:45,651,315...46,187,990
Ensembl chr 2:45,651,345...46,187,990
JBrowse link
G PROP1 PROP paired-like homeobox 1 decreases response to substance ISO PROP1 gene mutant form results in decreased susceptibility to Dobutamine CTD PMID:19414510 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression EXP Dobutamine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G REN renin multiple interactions
increases expression
increases secretion
increases activity
EXP Cycloheximide inhibits the reaction [Dobutamine results in increased secretion of REN protein]; Dactinomycin inhibits the reaction [Dobutamine results in increased secretion of REN protein]
Dobutamine results in increased expression of REN mRNA
Dobutamine results in increased activity of REN protein
CTD PMID:9203624 PMID:9209250 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
JBrowse link
G S100A1 S100 calcium binding protein A1 increases response to substance ISO S100A1 gene mutant form results in increased susceptibility to Dobutamine CTD PMID:18645228 NCBI chr 1:153,628,434...153,632,039
Ensembl chr 1:153,627,926...153,632,039
JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma increases expression ISO Dobutamine results in increased expression of SCNN1G mRNA CTD PMID:16638327 NCBI chr16:23,182,745...23,216,883
Ensembl chr16:23,182,745...23,216,883
JBrowse link
G SGCD sarcoglycan delta affects response to substance ISO SGCD affects the susceptibility to Dobutamine CTD PMID:20675662 NCBI chr 5:155,728,636...156,767,788
Ensembl chr 5:155,870,344...156,767,788
JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 increases degradation ISO Dobutamine deficiency results in increased degradation of SPTAN1 protein CTD PMID:15849228 NCBI chr 9:128,552,564...128,633,662
Ensembl chr 9:128,552,558...128,633,662
JBrowse link
G TAC1 tachykinin precursor 1 multiple interactions EXP Dobutamine promotes the reaction [TAC1 protein binds to and results in increased activity of TACR1 protein] CTD PMID:8994422 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
JBrowse link
G TACR1 tachykinin receptor 1 multiple interactions EXP Dobutamine promotes the reaction [TAC1 protein binds to and results in increased activity of TACR1 protein] CTD PMID:8994422 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520
JBrowse link
G TGFB1 transforming growth factor beta 1 increases expression ISO Dobutamine results in increased expression of TGFB1 mRNA CTD PMID:16760913 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFB2 transforming growth factor beta 2 increases expression ISO Dobutamine results in increased expression of TGFB2 mRNA CTD PMID:16760913 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
G TNF tumor necrosis factor decreases expression
decreases secretion
ISO Dobutamine results in decreased expression of TNF mRNA
Dobutamine results in decreased secretion of TNF protein
CTD PMID:12423672 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 decreases expression EXP Dobutamine results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 2:151,357,592...151,380,046
Ensembl chr 2:151,357,592...151,380,046
JBrowse link
G USF1 upstream transcription factor 1 multiple interactions EXP USF1 gene polymorphism promotes the reaction [Dobutamine results in increased metabolism of Lipids]; USF1 protein affects the reaction [Dobutamine results in increased metabolism of Lipids] CTD PMID:15985485 NCBI chr 1:161,039,251...161,045,977
Ensembl chr 1:161,039,251...161,045,977
JBrowse link
G VEGFA vascular endothelial growth factor A affects response to substance EXP
ISO
VEGFA protein affects the susceptibility to Dobutamine CTD PMID:11599061 PMID:14583313 PMID:19237429 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
maleimide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 multiple interactions EXP maleimide analog binds to and results in increased activity of TP53 protein mutant form CTD PMID:15998635 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
methamphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AANAT aralkylamine N-acetyltransferase decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of AANAT mRNA
Lithium inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]
CTD PMID:19149911 NCBI chr17:76,453,351...76,470,797
Ensembl chr17:76,453,351...76,470,117
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
decreases expression
ISO Melatonin inhibits the reaction [Methamphetamine results in decreased expression of ABCB1 protein] CTD PMID:28223141 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC6 ATP binding cassette subfamily C member 6 decreases expression
multiple interactions
EXP
ISO
Methamphetamine results in decreased expression of ABCC6 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCC6 mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr16:16,149,565...16,223,617
Ensembl chr16:16,149,565...16,223,522
JBrowse link
G ABCD3 ATP binding cassette subfamily D member 3 increases expression ISO Methamphetamine results in increased expression of ABCD3 mRNA CTD PMID:26307267 NCBI chr 1:94,418,086...94,518,663
Ensembl chr 1:94,418,389...94,518,666
JBrowse link
G ABCD4 ATP binding cassette subfamily D member 4 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of ABCD4 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCD4 mRNA
CTD PMID:19564919 NCBI chr14:74,285,269...74,303,062
Ensembl chr14:74,285,269...74,303,055
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCG2 mRNA
Methamphetamine results in decreased expression of ABCG2 mRNA
CTD PMID:19564919 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Methamphetamine results in increased expression of ABL1 mRNA CTD PMID:26307267 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G ABLIM1 actin binding LIM protein 1 increases expression ISO Methamphetamine results in increased expression of ABLIM1 mRNA CTD PMID:26307267 PMID:32035215 NCBI chr10:114,431,110...114,821,643
Ensembl chr10:114,431,113...114,768,061
JBrowse link
G ABRA actin binding Rho activating protein multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] affects the expression of ABRA mRNA
Methamphetamine results in increased expression of ABRA mRNA
CTD PMID:19564919 NCBI chr 8:106,759,483...106,809,073
Ensembl chr 8:106,759,483...106,770,244
JBrowse link
G ACACB acetyl-CoA carboxylase beta increases expression ISO Methamphetamine results in increased expression of ACACB mRNA CTD PMID:26307267 NCBI chr12:109,112,666...109,268,226
Ensembl chr12:109,116,595...109,268,226
JBrowse link
G ACIN1 apoptotic chromatin condensation inducer 1 increases expression ISO Methamphetamine results in increased expression of ACIN1 mRNA CTD PMID:26307267 NCBI chr14:23,058,564...23,095,614
Ensembl chr14:23,058,564...23,095,614
JBrowse link
G ACO1 aconitase 1 increases expression ISO Methamphetamine results in increased expression of ACO1 protein CTD PMID:19826936 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
JBrowse link
G ACO2 aconitase 2 increases expression ISO Methamphetamine results in increased expression of ACO2 protein CTD PMID:19826936 NCBI chr22:41,468,756...41,528,979
Ensembl chr22:41,447,830...41,529,273
JBrowse link
G ACOT1 acyl-CoA thioesterase 1 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ACOT1 mRNA
Methamphetamine results in decreased expression of ACOT1 mRNA
CTD PMID:19564919 NCBI chr14:73,493,021...73,543,799
Ensembl chr14:73,537,143...73,543,796
JBrowse link
G ACOX3 acyl-CoA oxidase 3, pristanoyl increases expression ISO Methamphetamine results in increased expression of ACOX3 mRNA CTD PMID:15644446 NCBI chr 4:8,366,263...8,440,723
Ensembl chr 4:8,366,282...8,440,723
JBrowse link
G ACRBP acrosin binding protein increases expression ISO Methamphetamine results in increased expression of ACRBP mRNA CTD PMID:26307267 NCBI chr12:6,638,075...6,647,432
Ensembl chr12:6,638,075...6,647,433
JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of ACSL5 mRNA
Lithium inhibits the reaction [Methamphetamine results in increased expression of ACSL5 mRNA]
CTD PMID:19149911 NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,116...112,428,379
JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 affects response to substance EXP ACSL6 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 5:131,949,973...132,012,068
Ensembl chr 5:131,949,973...132,012,243
JBrowse link
G ACTB actin beta decreases expression ISO Methamphetamine results in decreased expression of ACTB protein CTD PMID:19826936 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ACTC1 actin alpha cardiac muscle 1 decreases expression EXP Methamphetamine results in decreased expression of ACTC1 mRNA CTD PMID:25290377 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,230...34,795,549
JBrowse link
G ACTG1 actin gamma 1 decreases expression ISO Methamphetamine results in decreased expression of ACTG1 protein CTD PMID:19826936 NCBI chr17:81,509,971...81,512,799
Ensembl chr17:81,509,413...81,523,847
JBrowse link
G ACVRL1 activin A receptor like type 1 decreases methylation ISO Methamphetamine results in decreased methylation of ACVRL1 promoter CTD PMID:26307267 NCBI chr12:51,906,913...51,923,361
Ensembl chr12:51,906,908...51,923,361
JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 increases expression ISO Methamphetamine results in increased expression of ADAM15 mRNA CTD PMID:26307267 NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775
JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ADAMTS9 mRNA
Methamphetamine results in increased expression of ADAMTS9 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000
JBrowse link
G ADAMTSL5 ADAMTS like 5 increases expression ISO Methamphetamine results in increased expression of ADAMTSL5 mRNA CTD PMID:26307267 NCBI chr19:1,505,018...1,513,038
Ensembl chr19:1,505,022...1,513,604
JBrowse link
G ADCK2 aarF domain containing kinase 2 decreases expression ISO Methamphetamine results in decreased expression of ADCK2 mRNA CTD PMID:19564919 NCBI chr 7:140,672,895...140,695,114
Ensembl chr 7:140,672,945...140,696,261
JBrowse link
G ADCK5 aarF domain containing kinase 5 decreases expression ISO Methamphetamine results in decreased expression of ADCK5 mRNA CTD PMID:19564919 NCBI chr 8:144,373,762...144,393,242
Ensembl chr 8:144,373,101...144,393,242
JBrowse link
G ADCY3 adenylate cyclase 3 multiple interactions
decreases expression
ISO (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of ADCY3 mRNA] CTD PMID:11756511 NCBI chr 2:24,819,169...24,920,237
Ensembl chr 2:24,819,169...24,920,237
JBrowse link
G ADCY4 adenylate cyclase 4 increases expression ISO Methamphetamine results in increased expression of ADCY4 mRNA CTD PMID:26307267 NCBI chr14:24,318,359...24,335,071
Ensembl chr14:24,318,349...24,335,093
JBrowse link
G ADCY6 adenylate cyclase 6 increases expression ISO Methamphetamine results in increased expression of ADCY6 mRNA CTD PMID:26307267 NCBI chr12:48,766,194...48,789,089
Ensembl chr12:48,766,194...48,789,089
JBrowse link
G ADD2 adducin 2 increases expression ISO Methamphetamine results in increased expression of ADD2 mRNA CTD PMID:19564919 NCBI chr 2:70,656,784...70,768,200
Ensembl chr 2:70,607,618...70,768,225
JBrowse link
G ADGRF5 adhesion G protein-coupled receptor F5 increases expression ISO Methamphetamine results in increased expression of ADGRF5 mRNA CTD PMID:26307267 NCBI chr 6:46,852,522...46,954,954
Ensembl chr 6:46,852,522...46,954,943
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing decreases expression ISO Methamphetamine results in decreased expression of ADIPOQ mRNA CTD PMID:26307267 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADORA1 adenosine A1 receptor multiple interactions ISO [8-cyclopentyl-1,3-dimethylxanthine binds to and results in decreased activity of ADORA1 protein] inhibits the reaction [[Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine]; [Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine
[N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] promotes the reaction [Methamphetamine results in increased secretion of Dopamine]; [N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] which results in increased susceptibility to Methamphetamine
CTD PMID:7996441 PMID:11043458 NCBI chr 1:203,127,705...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G ADORA2A adenosine A2a receptor increases response to substance EXP ADORA2A gene SNP results in increased susceptibility to Methamphetamine CTD PMID:20799992 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
JBrowse link
G ADORA3 adenosine A3 receptor decreases expression
affects response to substance
ISO Methamphetamine results in decreased expression of ADORA3 mRNA
ADORA3 affects the susceptibility to Methamphetamine
CTD PMID:19564919 PMID:21867746 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
JBrowse link
G ADPGK ADP dependent glucokinase decreases expression ISO Methamphetamine results in decreased expression of ADPGK mRNA CTD PMID:19564919 NCBI chr15:72,751,294...72,783,776
Ensembl chr15:72,751,294...72,785,846
JBrowse link
G ADRA1B adrenoceptor alpha 1B affects response to substance ISO ADRA1B protein affects the susceptibility to Methamphetamine CTD PMID:12871582 NCBI chr 5:159,916,482...159,989,205
Ensembl chr 5:159,865,080...159,973,012
JBrowse link
G AGBL5 AGBL carboxypeptidase 5 increases expression ISO Methamphetamine results in increased expression of AGBL5 mRNA CTD PMID:26307267 NCBI chr 2:27,051,423...27,070,620
Ensembl chr 2:27,042,364...27,070,622
JBrowse link
G AGMAT agmatinase decreases expression ISO Methamphetamine results in decreased expression of AGMAT mRNA CTD PMID:19564919 NCBI chr 1:15,571,699...15,585,051
Ensembl chr 1:15,571,699...15,585,051
JBrowse link
G AGRN agrin increases expression ISO Methamphetamine results in increased expression of AGRN mRNA CTD PMID:26307267 NCBI chr 1:1,020,102...1,056,119
Ensembl chr 1:1,020,120...1,056,118
JBrowse link
G AGT angiotensinogen multiple interactions
increases expression
ISO candesartan cilexetil promotes the reaction [Methamphetamine results in increased expression of AGT protein] CTD PMID:33421459 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR1 angiotensin II receptor type 1 increases expression ISO Methamphetamine results in increased expression of AGTR1A protein CTD PMID:33421459 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G AHNAK AHNAK nucleoprotein increases expression ISO Methamphetamine results in increased expression of AHNAK mRNA CTD PMID:26307267 NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235
JBrowse link
G AHSA2P activator of HSP90 ATPase homolog 2, pseudogene multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of AHSA2 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of AHSA2 mRNA] CTD PMID:19564919 NCBI chr 2:61,177,418...61,188,925
Ensembl chr 2:61,177,418...61,191,203
JBrowse link
G AIF1 allograft inflammatory factor 1 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of AIF1 protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; Minocycline inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]
CTD PMID:26283213 PMID:29467000 PMID:32278788 PMID:32916201 NCBI chr 6:31,615,212...31,617,015
Ensembl chr 6:31,615,217...31,617,021
JBrowse link
G AJAP1 adherens junctions associated protein 1 increases expression EXP Methamphetamine results in increased expression of AJAP1 mRNA CTD PMID:25290377 NCBI chr 1:4,654,609...4,792,534
Ensembl chr 1:4,654,609...4,792,534
JBrowse link
G AK1 adenylate kinase 1 decreases expression ISO Methamphetamine results in decreased expression of AK1 protein CTD PMID:19826936 NCBI chr 9:127,866,480...127,885,542
Ensembl chr 9:127,866,486...127,877,675
JBrowse link
G AK5 adenylate kinase 5 affects response to substance EXP AK5 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 1:77,281,908...77,559,966
Ensembl chr 1:77,282,019...77,559,966
JBrowse link
G AKAP13 A-kinase anchoring protein 13 increases expression ISO Methamphetamine results in increased expression of AKAP13 mRNA CTD PMID:26307267 NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358
JBrowse link
G AKAP8L A-kinase anchoring protein 8 like increases expression ISO Methamphetamine results in increased expression of AKAP8L mRNA CTD PMID:26307267 NCBI chr19:15,380,050...15,418,988
Ensembl chr19:15,380,050...15,419,141
JBrowse link
G AKR7A2 aldo-keto reductase family 7 member A2 decreases methylation ISO Methamphetamine results in decreased methylation of AKR7A5 promoter CTD PMID:26307267 NCBI chr 1:19,302,708...19,312,146
Ensembl chr 1:19,303,965...19,312,144
JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases response to substance
increases phosphorylation
multiple interactions
affects phosphorylation
decreases phosphorylation
EXP
ISO
AKT1 gene SNP results in increased susceptibility to Methamphetamine
Methamphetamine results in increased phosphorylation of AKT1 protein
Luteolin inhibits the reaction [Methamphetamine results in increased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein
Methamphetamine affects the phosphorylation of AKT1 protein
[Rosiglitazone co-treated with Methamphetamine] results in increased phosphorylation of AKT1 protein
Methamphetamine results in decreased phosphorylation of AKT1 protein
rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein]
CTD PMID:15982448 PMID:29981415 PMID:30742852 PMID:31270305 PMID:32035215 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 increases expression EXP Methamphetamine results in increased expression of ALDH1A2 mRNA CTD PMID:25290377 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member decreases expression ISO Methamphetamine results in decreased expression of ALDH2 mRNA CTD PMID:15644446 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALDOC aldolase, fructose-bisphosphate C multiple interactions
increases expression
affects localization
ISO 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the localization of ALDOC mRNA]
Methamphetamine results in increased expression of ALDOC protein
CTD PMID:18299792 PMID:19826936 NCBI chr17:28,573,115...28,576,963
Ensembl chr17:28,573,115...28,576,948
JBrowse link
G ALG1 ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ALG1 mRNA
Methamphetamine results in decreased expression of ALG1 mRNA
CTD PMID:19564919 NCBI chr16:5,071,825...5,087,379
Ensembl chr16:5,033,702...5,087,379
JBrowse link
G ALS2CL ALS2 C-terminal like increases expression ISO Methamphetamine results in increased expression of ALS2CL mRNA CTD PMID:26307267 NCBI chr 3:46,668,995...46,693,693
Ensembl chr 3:46,668,995...46,693,704
JBrowse link
G AMDHD2 amidohydrolase domain containing 2 decreases expression ISO Methamphetamine results in decreased expression of AMDHD2 mRNA CTD PMID:19564919 NCBI chr16:2,520,362...2,531,422
Ensembl chr16:2,520,357...2,531,422
JBrowse link
G AMPD1 adenosine monophosphate deaminase 1 increases expression ISO Methamphetamine results in increased expression of AMPD1 mRNA CTD PMID:19564919 NCBI chr 1:114,673,098...114,695,546
Ensembl chr 1:114,673,090...114,695,618
JBrowse link
G AMPD3 adenosine monophosphate deaminase 3 decreases expression ISO Methamphetamine results in decreased expression of AMPD3 mRNA CTD PMID:15644446 NCBI chr11:10,450,388...10,507,579
Ensembl chr11:10,308,313...10,507,579
JBrowse link
G ANGEL1 angel homolog 1 decreases expression ISO Methamphetamine results in decreased expression of ANGEL1 mRNA CTD PMID:19564919 NCBI chr14:76,786,009...76,812,882
Ensembl chr14:76,786,009...76,826,246
JBrowse link
G ANGPT2 angiopoietin 2 increases expression EXP Methamphetamine results in increased expression of ANGPT2 mRNA CTD PMID:25290377 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409
JBrowse link
G ANKRD11 ankyrin repeat domain 11 increases expression ISO Methamphetamine results in increased expression of ANKRD11 mRNA CTD PMID:26307267 NCBI chr16:89,267,619...89,490,561
Ensembl chr16:89,267,630...89,490,561
JBrowse link
G ANKRD16 ankyrin repeat domain 16 decreases expression ISO Methamphetamine results in decreased expression of ANKRD16 mRNA CTD PMID:19564919 NCBI chr10:5,861,616...5,889,893
Ensembl chr10:5,861,616...5,889,906
JBrowse link
G ANKRD44 ankyrin repeat domain 44 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of ANKRD44 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ANKRD44 mRNA
CTD PMID:19564919 NCBI chr 2:196,962,617...197,310,787
Ensembl chr 2:196,967,017...197,311,173
JBrowse link
G ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO Methamphetamine results in decreased expression of ANKS1B mRNA CTD PMID:26307267 NCBI chr12:98,729,904...99,984,936
Ensembl chr12:98,726,457...99,984,654
JBrowse link
G ANO3 anoctamin 3 decreases expression ISO Methamphetamine results in decreased expression of ANO3 mRNA CTD PMID:32035215 NCBI chr11:26,188,808...26,667,907
Ensembl chr11:26,188,842...26,663,289
JBrowse link
G ANO6 anoctamin 6 increases expression ISO Methamphetamine results in increased expression of ANO6 mRNA CTD PMID:26307267 NCBI chr12:45,216,033...45,440,404
Ensembl chr12:45,215,987...45,482,280
JBrowse link
G ANXA3 annexin A3 decreases expression ISO Methamphetamine results in decreased expression of ANXA3 protein CTD PMID:19826936 NCBI chr 4:78,551,761...78,610,447
Ensembl chr 4:78,551,747...78,610,451
JBrowse link
G AOAH acyloxyacyl hydrolase affects response to substance EXP AOAH gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 7:36,509,313...36,724,544
Ensembl chr 7:36,512,941...36,724,549
JBrowse link
G AP1B1 adaptor related protein complex 1 subunit beta 1 increases expression ISO Methamphetamine results in increased expression of AP1B1 mRNA CTD PMID:26307267 NCBI chr22:29,327,680...29,388,570
Ensembl chr22:29,327,680...29,388,583
JBrowse link
G APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 increases expression ISO Methamphetamine results in increased expression of APEX2 mRNA CTD PMID:19149911 NCBI chr  X:55,000,363...55,009,057
Ensembl chr  X:55,000,363...55,009,057
JBrowse link
G APLNR apelin receptor decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of APLNR mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of APLNR mRNA
CTD PMID:19564919 NCBI chr11:57,233,591...57,237,250
Ensembl chr11:57,233,577...57,237,235
JBrowse link
G APOA2 apolipoprotein A2 decreases expression ISO Methamphetamine results in decreased expression of APOA2 mRNA CTD PMID:32035215 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631
JBrowse link
G APOD apolipoprotein D decreases expression ISO Methamphetamine results in decreased expression of APOD mRNA CTD PMID:28619521 NCBI chr 3:195,568,705...195,583,940
Ensembl chr 3:195,568,705...195,584,033
JBrowse link
G APOLD1 apolipoprotein L domain containing 1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of APOLD1 mRNA
Methamphetamine results in increased expression of APOLD1 mRNA
CTD PMID:19564919 NCBI chr12:12,725,917...12,791,466
Ensembl chr12:12,725,917...12,829,975
JBrowse link
G APP amyloid beta precursor protein multiple interactions
increases expression
increases secretion
ISO
EXP
Methamphetamine results in increased expression of and results in increased cleavage of APP protein
Rosiglitazone inhibits the reaction [Methamphetamine results in increased expression of APP protein]
Methamphetamine results in increased secretion of APP protein
CTD PMID:30367931 PMID:31270305 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 increases expression ISO Methamphetamine results in increased expression of APPL2 mRNA CTD PMID:26307267 NCBI chr12:105,173,297...105,236,174
Ensembl chr12:105,173,297...105,236,203
JBrowse link
G AR androgen receptor increases expression ISO Methamphetamine results in increased expression of AR mRNA CTD PMID:15644446 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 increases expression ISO Methamphetamine results in increased expression of ARAP3 mRNA CTD PMID:26307267 NCBI chr 5:141,653,401...141,682,230
Ensembl chr 5:141,653,401...141,682,230
JBrowse link
G ARC activity regulated cytoskeleton associated protein multiple interactions
increases expression
ISO CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA] CTD PMID:11085305 PMID:19564919 PMID:20298714 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479
JBrowse link
G AREG amphiregulin decreases expression ISO Methamphetamine results in decreased expression of AREG mRNA CTD PMID:26307267 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
JBrowse link
G ARG2 arginase 2 multiple interactions
increases expression
ISO Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] CTD PMID:19149911 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
JBrowse link
G ARHGAP29 Rho GTPase activating protein 29 increases expression ISO Methamphetamine results in increased expression of ARHGAP29 mRNA CTD PMID:26307267 NCBI chr 1:94,168,905...94,275,068
Ensembl chr 1:94,148,988...94,275,068
JBrowse link
G ARHGAP9 Rho GTPase activating protein 9 increases methylation ISO Methamphetamine results in increased methylation of ARHGAP9 promoter CTD PMID:26307267 NCBI chr12:57,472,262...57,488,824
Ensembl chr12:57,472,264...57,488,814
JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha increases expression ISO Methamphetamine results in increased expression of ARHGDIA protein CTD PMID:19826936 NCBI chr17:81,867,719...81,871,337
Ensembl chr17:81,867,721...81,871,378
JBrowse link
G ARHGEF1 Rho guanine nucleotide exchange factor 1 increases expression ISO Methamphetamine results in increased expression of ARHGEF1 mRNA CTD PMID:26307267 NCBI chr19:41,883,184...41,907,452
Ensembl chr19:41,883,173...41,930,150
JBrowse link
G ARHGEF10 Rho guanine nucleotide exchange factor 10 increases expression ISO Methamphetamine results in increased expression of ARHGEF10 mRNA CTD PMID:26307267 NCBI chr 8:1,823,926...1,958,641
Ensembl chr 8:1,823,926...1,958,641
JBrowse link
G ARHGEF15 Rho guanine nucleotide exchange factor 15 increases expression ISO Methamphetamine results in increased expression of ARHGEF15 mRNA CTD PMID:26307267 NCBI chr17:8,310,241...8,322,516
Ensembl chr17:8,310,241...8,322,514
JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO Methamphetamine results in increased expression of ARHGEF2 mRNA CTD PMID:26307267 NCBI chr 1:155,946,851...155,991,262
Ensembl chr 1:155,946,851...156,007,070
JBrowse link
G ARHGEF25 Rho guanine nucleotide exchange factor 25 increases methylation ISO Methamphetamine results in increased methylation of ARHGEF25 promoter CTD PMID:26307267 NCBI chr12:57,610,116...57,617,245
Ensembl chr12:57,610,180...57,617,245
JBrowse link
G ARID1A AT-rich interaction domain 1A increases methylation
increases expression
ISO Methamphetamine results in increased methylation of ARID1A promoter
Methamphetamine results in increased expression of ARID1A mRNA
CTD PMID:26307267 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104
JBrowse link
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 increases expression ISO Methamphetamine results in increased expression of ARIH1 mRNA CTD PMID:19564919 NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
JBrowse link
G ARL14EP ADP ribosylation factor like GTPase 14 effector protein decreases expression ISO Methamphetamine results in decreased expression of ARL14EP mRNA CTD PMID:19564919 NCBI chr11:30,323,104...30,338,458
Ensembl chr11:30,323,104...30,338,223
JBrowse link
G ARL5B ADP ribosylation factor like GTPase 5B multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ARL5B mRNA
Methamphetamine results in increased expression of ARL5B mRNA
CTD PMID:19564919 NCBI chr10:18,659,335...18,681,639
Ensembl chr10:18,659,431...18,681,639
JBrowse link
G ARNT2 aryl hydrocarbon receptor nuclear translocator 2 increases expression ISO Methamphetamine results in increased expression of ARNT2 mRNA CTD PMID:15644446 NCBI chr15:80,404,382...80,597,933
Ensembl chr15:80,404,350...80,597,933
JBrowse link
G ARRB2 arrestin beta 2 increases response to substance EXP ARRB2 gene SNP results in increased susceptibility to Methamphetamine CTD PMID:17233643 NCBI chr17:4,710,619...4,721,500
Ensembl chr17:4,710,596...4,721,499
JBrowse link
G ARRDC2 arrestin domain containing 2 increases expression ISO Methamphetamine results in increased expression of ARRDC2 mRNA CTD PMID:26307267 NCBI chr19:18,001,124...18,014,102
Ensembl chr19:18,001,132...18,014,102
JBrowse link
G ASB14 ankyrin repeat and SOCS box containing 14 increases expression ISO Methamphetamine results in increased expression of ASB14 mRNA CTD PMID:26307267 NCBI chr 3:57,268,342...57,293,048
Ensembl chr 3:57,268,342...57,292,685
JBrowse link
G ASIC3 acid sensing ion channel subunit 3 increases expression ISO Methamphetamine results in increased expression of ASIC3 mRNA CTD PMID:15644446 NCBI chr 7:151,048,292...151,052,756
Ensembl chr 7:151,048,292...151,052,756
JBrowse link
G ASL argininosuccinate lyase decreases expression ISO Methamphetamine results in decreased expression of ASL mRNA CTD PMID:19564919 NCBI chr 7:66,075,819...66,093,576
Ensembl chr 7:66,075,800...66,094,697
JBrowse link
G ASPM assembly factor for spindle microtubules decreases expression EXP Methamphetamine results in decreased expression of ASPM mRNA CTD PMID:25290377 NCBI chr 1:197,084,127...197,146,669
Ensembl chr 1:197,084,121...197,146,694
JBrowse link
G ASTN2 astrotactin 2 affects response to substance EXP ASTN2 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 9:116,423,112...117,415,057
Ensembl chr 9:116,423,112...117,415,070
JBrowse link
G ATF3 activating transcription factor 3 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ATF3 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF3 mRNA]
Methamphetamine results in increased expression of ATF3 mRNA; Methamphetamine results in increased expression of ATF3 protein
CTD PMID:19564919 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATF4 activating transcription factor 4 multiple interactions
increases expression
ISO
EXP
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 protein]
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein]
Methamphetamine results in increased expression of ATF4 mRNA; Methamphetamine results in increased expression of ATF4 protein
CTD PMID:19564919 PMID:27323860 NCBI chr22:39,514,494...39,522,686
Ensembl chr22:39,519,695...39,522,683
JBrowse link
G ATF6 activating transcription factor 6 increases expression
affects localization
multiple interactions
increases cleavage
ISO
EXP
Methamphetamine results in increased expression of ATF6 mRNA; Methamphetamine results in increased expression of ATF6 protein
Methamphetamine affects the localization of ATF6 protein
ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 protein]; Methamphetamine results in decreased expression of and results in increased cleavage of ATF6 protein; Naltrexone inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein]
Melatonin inhibits the reaction [Methamphetamine results in increased expression of ATF6 protein]
CTD PMID:19564919 PMID:27323860 PMID:28070110 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
JBrowse link
G ATG14 autophagy related 14 increases expression ISO Methamphetamine results in increased expression of ATG14 mRNA CTD PMID:32676729 NCBI chr14:55,366,391...55,411,830
Ensembl chr14:55,366,391...55,411,830
JBrowse link
G ATG16L1 autophagy related 16 like 1 increases expression ISO Methamphetamine results in increased expression of ATG16L1 mRNA CTD PMID:32676729 NCBI chr 2:233,251,647...233,295,674
Ensembl chr 2:233,210,051...233,295,674
JBrowse link
G ATG2A autophagy related 2A increases expression ISO Methamphetamine results in increased expression of ATG2A mRNA CTD PMID:32676729 NCBI chr11:64,894,546...64,917,241
Ensembl chr11:64,894,546...64,917,211
JBrowse link
G ATG5 autophagy related 5 multiple interactions
increases expression
ISO Luteolin inhibits the reaction [Methamphetamine results in increased expression of ATG5 protein]
Methamphetamine results in increased expression of ATG5 mRNA; Methamphetamine results in increased expression of ATG5 protein
CTD PMID:32035215 PMID:32676729 PMID:33359793 NCBI chr 6:106,184,476...106,325,789
Ensembl chr 6:106,045,423...106,325,791
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression ISO Methamphetamine results in decreased expression of ATP1A1 mRNA CTD PMID:19149911 NCBI chr 1:116,372,986...116,410,259
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
decreases expression
ISO Lithium inhibits the reaction [Methamphetamine results in decreased expression of ATP2A2 mRNA] CTD PMID:19149911 NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta decreases expression ISO Methamphetamine results in decreased expression of ATP5F1B protein CTD PMID:19826936 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d decreases expression ISO Methamphetamine results in decreased expression of ATP5H protein CTD PMID:17904249 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985
JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 increases expression ISO Methamphetamine results in increased expression of ATP6V0A1 mRNA CTD PMID:26307267 NCBI chr17:42,458,874...42,522,579
Ensembl chr17:42,458,844...42,522,582
JBrowse link
G ATP6V0E2 ATPase H+ transporting V0 subunit e2 increases expression ISO Methamphetamine results in increased expression of ATP6V0E2 mRNA CTD PMID:32035215 NCBI chr 7:149,872,964...149,880,713
Ensembl chr 7:149,872,968...149,891,204
JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 decreases expression ISO Methamphetamine results in decreased expression of ATP6V1B2 protein CTD PMID:16181420 PMID:19826936 NCBI chr 8:20,197,375...20,226,852
Ensembl chr 8:20,197,381...20,226,819
JBrowse link
G ATP6V1C2 ATPase H+ transporting V1 subunit C2 decreases expression ISO Methamphetamine results in decreased expression of ATP6V1C2 mRNA CTD PMID:19564919 NCBI chr 2:10,720,973...10,785,110
Ensembl chr 2:10,721,100...10,785,110
JBrowse link
G ATXN2L ataxin 2 like increases expression ISO Methamphetamine results in increased expression of ATXN2L mRNA CTD PMID:26307267 NCBI chr16:28,822,999...28,837,237
Ensembl chr16:28,822,999...28,837,237
JBrowse link
G ATXN7L1 ataxin 7 like 1 increases expression ISO Methamphetamine results in increased expression of ATXN7L1 mRNA CTD PMID:26307267 NCBI chr 7:105,604,772...105,876,599
Ensembl chr 7:105,604,772...105,876,599
JBrowse link
G AURKC aurora kinase C decreases expression ISO Methamphetamine results in decreased expression of AURKC mRNA CTD PMID:19564919 NCBI chr19:57,230,317...57,235,550
Ensembl chr19:57,230,802...57,235,548
JBrowse link
G AVP arginine vasopressin affects expression
multiple interactions
ISO Methamphetamine affects the expression of AVP mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of AVP mRNA
CTD PMID:19564919 NCBI chr20:3,082,556...3,093,521
Ensembl chr20:3,082,556...3,084,724
JBrowse link
G B3GALT4 beta-1,3-galactosyltransferase 4 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of B3GALT4 mRNA
Methamphetamine results in decreased expression of B3GALT4 mRNA
CTD PMID:19564919 NCBI chr 6:33,277,123...33,278,825
Ensembl chr 6:33,277,123...33,284,832
JBrowse link
G BACE1 beta-secretase 1 increases expression ISO Methamphetamine results in increased expression of BACE1 protein CTD PMID:30367931 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259
JBrowse link
G BACH2 BTB domain and CNC homolog 2 decreases expression ISO Methamphetamine results in decreased expression of BACH2 mRNA CTD PMID:26307267 NCBI chr 6:89,926,528...90,296,843
Ensembl chr 6:89,926,528...90,296,908
JBrowse link
G BAIAP3 BAI1 associated protein 3 increases expression EXP Methamphetamine results in increased expression of BAIAP3 mRNA CTD PMID:25290377 NCBI chr16:1,333,645...1,349,439
Ensembl chr16:1,333,638...1,349,441
JBrowse link
G BAK1 BCL2 antagonist/killer 1 multiple interactions
increases expression
EXP [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAK1 protein
Methamphetamine results in increased expression of BAK1 protein
CTD PMID:23820845 NCBI chr 6:33,572,552...33,580,296
Ensembl chr 6:33,572,547...33,580,293
JBrowse link
G BANP BTG3 associated nuclear protein increases expression ISO Methamphetamine results in increased expression of BANP mRNA CTD PMID:26307267 NCBI chr16:87,949,216...88,077,318
Ensembl chr16:87,949,244...88,077,318
JBrowse link
G BARD1 BRCA1 associated RING domain 1 decreases expression ISO Methamphetamine results in decreased expression of BARD1 mRNA CTD PMID:28341135 NCBI chr 2:214,725,645...214,809,683
Ensembl chr 2:214,725,646...214,809,683
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein]
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of BAX protein]
Methamphetamine results in increased expression of BAX mRNA; Methamphetamine results in increased expression of BAX protein
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX protein; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of BAX protein]
CTD PMID:19149911 PMID:23820845 PMID:26307267 PMID:26524635 PMID:26923100 PMID:29467000 PMID:31059759 PMID:31422080 PMID:32035215 PMID:32203791 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BAZ1B bromodomain adjacent to zinc finger domain 1B increases expression ISO Methamphetamine results in increased expression of BAZ1B mRNA CTD PMID:26307267 NCBI chr 7:73,440,406...73,522,293
Ensembl chr 7:73,440,406...73,522,293
JBrowse link
G BAZ2A bromodomain adjacent to zinc finger domain 2A increases expression ISO Methamphetamine results in increased expression of BAZ2A mRNA CTD PMID:26307267 NCBI chr12:56,595,596...56,636,816
Ensembl chr12:56,595,596...56,636,816
JBrowse link
G BBC3 BCL2 binding component 3 multiple interactions
increases expression
EXP
ISO
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]
BBC3 protein promotes the reaction [Methamphetamine results in increased expression of NOS2 protein]
Methamphetamine results in increased expression of BBC3 protein
Methamphetamine results in increased expression of BBC3 mRNA; Methamphetamine results in increased expression of BBC3 protein
CTD PMID:23820845 PMID:26524635 PMID:30394308 NCBI chr19:47,220,822...47,232,998
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BCL2 BCL2 apoptosis regulator affects response to substance
increases expression
decreases expression
multiple interactions
ISO
EXP
BCL2 protein affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of BCL2 protein
Methamphetamine results in decreased expression of BCL2 protein
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2 mRNA; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]
Methamphetamine results in decreased expression of BCL2 mRNA; Methamphetamine results in decreased expression of BCL2 protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SOD1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]
BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Olanzapine inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]
CTD PMID:11457507 PMID:12050851 PMID:15276877 PMID:19149911 PMID:23820845 PMID:26524635 PMID:26923100 PMID:29467000 PMID:31059759 PMID:31422080 PMID:32203791 PMID:32676729 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 affects expression
multiple interactions
decreases expression
increases methylation
increases expression
ISO
EXP
Methamphetamine affects the expression of BCL2L1 mRNA alternative form
EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]
Methamphetamine results in increased methylation of BCL2L1 promoter
Methamphetamine results in increased expression of BCL2L1 mRNA
Methamphetamine results in decreased expression of BCL2L1 mRNA
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2L1 mRNA
CTD PMID:10336889 PMID:23820845 PMID:26307267 PMID:31422080 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCL2L11 BCL2 like 11 multiple interactions
increases expression
EXP [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein
Methamphetamine results in increased expression of BCL2L11 protein
CTD PMID:23820845 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,445
JBrowse link
G BCL2L15 BCL2 like 15 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL2L15 mRNA
Methamphetamine results in increased expression of BCL2L15 mRNA
CTD PMID:19564919 NCBI chr 1:113,876,816...113,887,581
Ensembl chr 1:113,876,816...113,887,581
JBrowse link
G BCL2L2 BCL2 like 2 increases expression ISO Methamphetamine results in increased expression of BCL2L2 mRNA CTD PMID:26307267 NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,751
JBrowse link
G BCL6 BCL6 transcription repressor multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL6 mRNA
Methamphetamine results in increased expression of BCL6 mRNA
CTD PMID:19564919 NCBI chr 3:187,721,377...187,745,472
Ensembl chr 3:187,721,377...187,745,725
JBrowse link
G BCL9L BCL9 like increases expression ISO Methamphetamine results in increased expression of BCL9L mRNA CTD PMID:26307267 NCBI chr11:118,896,136...118,926,071
Ensembl chr11:118,893,875...118,925,926
JBrowse link
G BDNF brain derived neurotrophic factor increases response to substance
multiple interactions
decreases expression
increases expression
affects response to substance
EXP
ISO
BDNF gene SNP results in increased susceptibility to Methamphetamine
Metformin inhibits the reaction [Methamphetamine results in decreased expression of BDNF protein]
Methamphetamine results in increased expression of BDNF protein
BDNF protein affects the susceptibility to Methamphetamine
BDNF gene polymorphism affects the susceptibility to Methamphetamine
CTD PMID:15050682 PMID:16039058 PMID:19462300 PMID:20736000 PMID:27373168 PMID:30742852 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BECN1 beclin 1 multiple interactions
increases expression
increases phosphorylation
ISO
EXP
CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein]
Methamphetamine results in increased phosphorylation of BECN1 protein
DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]
CTD PMID:26825372 PMID:31059759 PMID:32035215 PMID:32676729 PMID:33359793 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 affects expression
multiple interactions
ISO Methamphetamine affects the expression of BHMT2 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of BHMT2 mRNA
CTD PMID:19564919 NCBI chr 5:79,069,767...79,090,069
Ensembl chr 5:79,069,767...79,090,069
JBrowse link
G BID BH3 interacting domain death agonist increases expression
multiple interactions
EXP Methamphetamine results in increased expression of BID mRNA; Methamphetamine results in increased expression of BID protein modified form
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form
CTD PMID:23820845 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
JBrowse link
G BIN1 bridging integrator 1 decreases expression ISO Methamphetamine results in decreased expression of BIN1 protein CTD PMID:19826936 NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 decreases expression EXP Methamphetamine results in decreased expression of BIRC5 mRNA CTD PMID:25290377 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase increases expression ISO Methamphetamine results in increased expression of BRAF mRNA CTD PMID:19564919 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G BRD2 bromodomain containing 2 increases expression ISO Methamphetamine results in increased expression of BRD2 mRNA CTD PMID:26307267 NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505
JBrowse link
G BRD9 bromodomain containing 9 increases expression ISO Methamphetamine results in increased expression of BRD9 mRNA CTD PMID:26307267 NCBI chr 5:863,735...892,803
Ensembl chr 5:850,291...892,801
JBrowse link
G BRWD1 bromodomain and WD repeat domain containing 1 increases expression ISO Methamphetamine results in increased expression of BRWD1 mRNA CTD PMID:26307267 NCBI chr21:39,184,176...39,321,595
Ensembl chr21:39,184,176...39,321,559
JBrowse link
G BSPRY B-box and SPRY domain containing decreases expression ISO Methamphetamine results in decreased expression of BSPRY mRNA CTD PMID:19564919 NCBI chr 9:113,349,541...113,371,233
Ensembl chr 9:113,349,541...113,371,233
JBrowse link
G BST2 bone marrow stromal cell antigen 2 increases expression ISO Methamphetamine results in increased expression of BST2 mRNA CTD PMID:32035215 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630
JBrowse link
G BTAF1 B-TFIID TATA-box binding protein associated factor 1 increases expression ISO Methamphetamine results in increased expression of BTAF1 mRNA CTD PMID:19564919 NCBI chr10:91,923,770...92,031,437
Ensembl chr10:91,923,770...92,030,325
JBrowse link
G BTG2 BTG anti-proliferation factor 2 increases expression ISO Methamphetamine results in increased expression of BTG2 mRNA CTD PMID:19564919 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Methamphetamine results in decreased expression of BUB1B mRNA CTD PMID:28341135 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123
JBrowse link
G C11orf96 chromosome 11 open reading frame 96 increases expression ISO Methamphetamine results in increased expression of RGD1564664 mRNA CTD PMID:19564919 NCBI chr11:43,942,637...43,943,878
Ensembl chr11:43,925,342...43,943,878
JBrowse link
G C16orf87 chromosome 16 open reading frame 87 increases expression ISO Methamphetamine results in increased expression of RGD1308706 mRNA CTD PMID:19564919 NCBI chr16:46,796,603...46,831,471
Ensembl chr16:46,796,603...46,831,180
JBrowse link
G C16orf89 chromosome 16 open reading frame 89 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of RGD1565166 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RGD1565166 mRNA
CTD PMID:19564919 NCBI chr16:5,042,772...5,065,971
Ensembl chr16:5,044,122...5,066,110
JBrowse link
G C1orf210 chromosome 1 open reading frame 210 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RGD1305347 mRNA
Methamphetamine results in decreased expression of RGD1305347 mRNA
CTD PMID:19564919 NCBI chr 1:43,281,877...43,285,840
Ensembl chr 1:43,281,877...43,285,617
JBrowse link
G C1QL1 complement C1q like 1 decreases expression ISO Methamphetamine results in decreased expression of C1QL1 mRNA CTD PMID:19564919 NCBI chr17:44,959,693...44,968,303
Ensembl chr17:44,959,693...44,968,303
JBrowse link
G C1QTNF7 C1q and TNF related 7 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of C1QTNF7 mRNA
Methamphetamine results in decreased expression of C1QTNF7 mRNA
CTD PMID:19564919 NCBI chr 4:15,339,818...15,446,169
Ensembl chr 4:15,339,818...15,446,167
JBrowse link
G C2CD2 C2 calcium dependent domain containing 2 increases expression ISO Methamphetamine results in increased expression of C2CD2 mRNA CTD PMID:19564919 NCBI chr21:41,885,110...41,954,018
Ensembl chr21:41,885,112...41,954,018
JBrowse link
G C3orf33 chromosome 3 open reading frame 33 decreases expression ISO Methamphetamine results in decreased expression of RGD1565059 mRNA CTD PMID:19564919 NCBI chr 3:155,762,617...155,806,278
Ensembl chr 3:155,762,617...155,806,278
JBrowse link
G C4BPB complement component 4 binding protein beta decreases expression ISO Methamphetamine results in decreased expression of C4BPB mRNA CTD PMID:19564919 NCBI chr 1:207,088,795...207,099,993
Ensembl chr 1:207,088,860...207,099,993
JBrowse link
G C8G complement C8 gamma chain decreases expression ISO Methamphetamine results in decreased expression of C8G mRNA CTD PMID:19564919 NCBI chr 9:136,944,870...136,946,981
Ensembl chr 9:136,945,185...136,946,975
JBrowse link
G C8orf58 chromosome 8 open reading frame 58 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of RGD1308117 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RGD1308117 mRNA
CTD PMID:19564919 NCBI chr 8:22,599,599...22,604,142
Ensembl chr 8:22,599,599...22,604,150
JBrowse link
G CA1 carbonic anhydrase 1 increases expression ISO Methamphetamine results in increased expression of CAR1 protein CTD PMID:19826936 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014
JBrowse link
G CA11 carbonic anhydrase 11 decreases expression ISO Methamphetamine results in decreased expression of CAR11 mRNA CTD PMID:32035215 NCBI chr19:48,637,946...48,646,187
Ensembl chr19:48,637,946...48,646,187
JBrowse link
G CA4 carbonic anhydrase 4 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CAR4 mRNA
Methamphetamine results in decreased expression of CAR4 mRNA
CTD PMID:19564919 NCBI chr17:60,149,942...60,179,021
Ensembl chr17:60,149,942...60,170,899
JBrowse link
G CA5B carbonic anhydrase 5B increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CAR5B mRNA
Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CAR5B mRNA]
CTD PMID:19149911 NCBI chr  X:15,738,270...15,788,411
Ensembl chr  X:15,688,830...15,788,411
JBrowse link
G CAB39L calcium binding protein 39 like decreases expression ISO Methamphetamine results in decreased expression of CAB39L mRNA CTD PMID:26307267 NCBI chr13:49,308,650...49,444,851
Ensembl chr13:49,308,650...49,444,064
JBrowse link
G CABIN1 calcineurin binding protein 1 increases expression ISO Methamphetamine results in increased expression of CABIN1 mRNA CTD PMID:26307267 NCBI chr22:24,011,192...24,178,628
Ensembl chr22:24,011,192...24,178,628
JBrowse link
G CABYR calcium binding tyrosine phosphorylation regulated increases expression ISO Methamphetamine results in increased expression of CABYR mRNA CTD PMID:26307267 NCBI chr18:24,138,956...24,161,600
Ensembl chr18:24,138,987...24,161,600
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of CACNA1C promoter
Methamphetamine results in increased expression of CACNA1C mRNA; Methamphetamine results in increased expression of CACNA1C protein
CTD PMID:26307267 NCBI chr12:1,969,552...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects response to substance
increases expression
multiple interactions
ISO CACNA2D1 protein affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of CACNA2D1 mRNA; Methamphetamine results in increased expression of CACNA2D1 protein
[gabapentin binds to and results in decreased activity of CACNA2D1 protein] which results in decreased susceptibility to Methamphetamine; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; gabapentin inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]
CTD PMID:20340177 PMID:21182903 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,777
JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 increases expression ISO Methamphetamine results in increased expression of CACNB4 mRNA CTD PMID:19564919 NCBI chr 2:151,832,771...152,099,167
Ensembl chr 2:151,832,771...152,099,167
JBrowse link
G CACYBP calcyclin binding protein increases expression ISO Methamphetamine results in increased expression of CACYBP mRNA CTD PMID:19564919 NCBI chr 1:174,999,435...175,012,027
Ensembl chr 1:174,999,163...175,012,027
JBrowse link
G CALB2 calbindin 2 decreases expression ISO Methamphetamine results in decreased expression of CALB2 mRNA CTD PMID:28619521 NCBI chr16:71,358,723...71,390,438
Ensembl chr16:71,358,713...71,390,436
JBrowse link
G CALHM2 calcium homeostasis modulator family member 2 increases expression ISO Methamphetamine results in increased expression of CALHM2 mRNA CTD PMID:19564919 NCBI chr10:103,446,783...103,452,403
Ensembl chr10:103,446,786...103,452,402
JBrowse link
G CAMTA2 calmodulin binding transcription activator 2 increases expression ISO Methamphetamine results in increased expression of CAMTA2 mRNA CTD PMID:26307267 NCBI chr17:4,967,993...4,988,281
Ensembl chr17:4,967,992...4,987,675
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta decreases expression ISO Methamphetamine results in decreased expression of CAPZB protein CTD PMID:16181420 NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539
JBrowse link
G CARHSP1 calcium regulated heat stable protein 1 decreases expression ISO Methamphetamine results in decreased expression of CARHSP1 mRNA CTD PMID:19564919 NCBI chr16:8,852,942...8,869,006
Ensembl chr16:8,852,942...8,869,012
JBrowse link
G CARNS1 carnosine synthase 1 increases expression ISO Methamphetamine results in increased expression of CARNS1 mRNA CTD PMID:26307267 NCBI chr11:67,415,678...67,425,607
Ensembl chr11:67,414,968...67,425,607
JBrowse link
G CASP1 caspase 1 multiple interactions
increases expression
increases cleavage
ISO MIR143 mRNA affects the reaction [Methamphetamine results in increased cleavage of CASP1 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased cleavage of CASP1 protein]
Methamphetamine results in increased expression of CASP1 protein
CTD PMID:30394308 PMID:33359793 NCBI chr11:105,025,443...105,035,591
Ensembl chr11:105,025,443...105,035,250
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) increases cleavage
decreases expression
multiple interactions
increases expression
ISO
EXP
Methamphetamine results in increased cleavage of CASP12 protein
Methamphetamine results in decreased expression of CASP12 protein
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP12 protein]
Methamphetamine results in increased expression of CASP12 mRNA; Methamphetamine results in increased expression of CASP12 protein
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased cleavage of CASP12 protein]
CTD PMID:28070110 PMID:28619521 PMID:29705343 PMID:32203791 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G CASP2 caspase 2 increases expression ISO Methamphetamine results in increased expression of CASP2 mRNA CTD PMID:19564919 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696
JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity
decreases expression
increases cleavage
decreases cleavage
affects cleavage
increases expression
ISO
EXP
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; [Methamphetamine co-treated with tin protoporphyrin IX] results in increased cleavage of CASP3 protein; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; JUN protein affects the reaction [Methamphetamine results in increased activity of CASP3 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]
Methamphetamine results in decreased expression of CASP3 protein
Methamphetamine results in decreased cleavage of CASP3 protein
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP3 protein; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP3 protein]
Methamphetamine affects the cleavage of CASP3 protein
BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of CASP3 protein]; KN 93 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; Luteolin inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein; Nifedipine inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; W 7 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; wedelolactone inhibits the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]
Methamphetamine results in increased expression of CASP3 mRNA; Methamphetamine results in increased expression of CASP3 protein modified form
CTD PMID:12391261 PMID:19149911 PMID:19442829 PMID:23933405 PMID:25127757 PMID:25523949 PMID:25631491 PMID:26524635 PMID:26825372 PMID:26923100 PMID:27323860 PMID:28341135 PMID:29467000 PMID:30450033 PMID:31059759 PMID:31422080 PMID:32035215 PMID:32203791 PMID:32382956 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP4 caspase 4 multiple interactions
increases expression
ISO CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA]
Methamphetamine results in increased expression of CASP4 mRNA; Methamphetamine results in increased expression of CASP4 protein alternative form
CTD PMID:19149911 PMID:25631491 PMID:28619521 NCBI chr11:104,942,866...104,968,596
Ensembl chr11:104,942,866...104,969,366
JBrowse link
G CASP6 caspase 6 increases cleavage ISO Methamphetamine results in increased cleavage of CASP6 protein CTD PMID:32676729 NCBI chr 4:109,688,628...109,703,445
Ensembl chr 4:109,688,622...109,703,583
JBrowse link
G CASP9 caspase 9 multiple interactions
increases cleavage
EXP
ISO
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP9 protein; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein] CTD PMID:27323860 PMID:32676729 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases expression
increases activity
multiple interactions
decreases activity
EXP
ISO
Methamphetamine results in decreased expression of CAT protein
Methamphetamine results in increased activity of CAT protein
ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of CAT protein]
Methamphetamine results in decreased activity of CAT protein
Taurine inhibits the reaction [Methamphetamine results in decreased activity of CAT protein]
CTD PMID:12797468 PMID:19948197 PMID:23041169 PMID:24430743 PMID:29467000 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV1 caveolin 1 increases expression ISO Methamphetamine results in increased expression of CAV1 mRNA CTD PMID:32035215 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CBLL1 Cbl proto-oncogene like 1 increases expression ISO Methamphetamine results in increased expression of CBLL1 mRNA CTD PMID:19564919 NCBI chr 7:107,743,836...107,764,997
Ensembl chr 7:107,743,949...107,761,667
JBrowse link
G CBR1 carbonyl reductase 1 decreases expression ISO Methamphetamine results in decreased expression of CBR1 mRNA CTD PMID:15644446 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
JBrowse link
G CBX1 chromobox 1 decreases expression ISO Methamphetamine results in decreased expression of CBX1 mRNA CTD PMID:26307267 NCBI chr17:48,070,059...48,101,478
Ensembl chr17:48,070,052...48,101,478
JBrowse link
G CBX8 chromobox 8 decreases expression ISO Methamphetamine results in decreased expression of CBX8 mRNA CTD PMID:19564919 NCBI chr17:79,792,132...79,797,077
Ensembl chr17:79,792,132...79,801,683
JBrowse link
G CC2D1B coiled-coil and C2 domain containing 1B multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CC2D1B mRNA
Methamphetamine results in decreased expression of CC2D1B mRNA
CTD PMID:19564919 NCBI chr 1:52,348,437...52,366,291
Ensembl chr 1:52,345,723...52,366,205
JBrowse link
G CCDC116 coiled-coil domain containing 116 increases expression ISO Methamphetamine results in increased expression of CCDC116 mRNA CTD PMID:19564919 NCBI chr22:21,632,121...21,637,329
Ensembl chr22:21,632,716...21,637,329
JBrowse link
G CCDC117 coiled-coil domain containing 117 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CCDC117 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CCDC117 mRNA
CTD PMID:19564919 NCBI chr22:28,772,695...28,789,301
Ensembl chr22:28,772,674...28,789,301
JBrowse link
G CCDC51 coiled-coil domain containing 51 increases methylation ISO Methamphetamine results in increased methylation of CCDC51 promoter CTD PMID:26307267 NCBI chr 3:48,432,170...48,446,652
Ensembl chr 3:48,432,164...48,440,456
JBrowse link
G CCDC57 coiled-coil domain containing 57 decreases expression ISO Methamphetamine results in decreased expression of CCDC57 mRNA CTD PMID:32035215 NCBI chr17:82,101,458...82,212,892
Ensembl chr17:82,101,460...82,212,830
JBrowse link
G CCHCR1 coiled-coil alpha-helical rod protein 1 affects response to substance EXP CCHCR1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 6:31,142,439...31,158,209
Ensembl chr 6:31,142,439...31,158,238
JBrowse link
G CCK cholecystokinin multiple interactions ISO CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; CCK protein modified form inhibits the reaction [Methamphetamine results in increased phosphorylation of NCF1 protein]
CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]
CTD PMID:27565679 PMID:32916201 NCBI chr 3:42,257,826...42,266,185
Ensembl chr 3:42,257,825...42,266,185
JBrowse link
G CCKBR cholecystokinin B receptor increases expression ISO Methamphetamine results in increased expression of CCKBR mRNA CTD PMID:32916201 NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127
JBrowse link
G CCL13 C-C motif chemokine ligand 13 increases expression ISO Methamphetamine results in increased expression of CCL12 mRNA CTD PMID:28341135 NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610
JBrowse link
G CCL4 C-C motif chemokine ligand 4 increases expression ISO Methamphetamine results in increased expression of CCL4 mRNA CTD PMID:19564919 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL5 C-C motif chemokine ligand 5 decreases expression ISO Methamphetamine results in decreased expression of CCL5 mRNA CTD PMID:19564919 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCN1 cellular communication network factor 1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CCN1 mRNA
Methamphetamine results in increased expression of CCN1 mRNA
CTD PMID:19564919 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
JBrowse link
G CCNA1 cyclin A1 multiple interactions
decreases expression
ISO Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCNA1 mRNA] CTD PMID:19149911 NCBI chr13:36,430,488...36,442,870
Ensembl chr13:36,431,520...36,442,870
JBrowse link
G CCNA2 cyclin A2 decreases expression ISO Methamphetamine results in decreased expression of CCNA2 mRNA; Methamphetamine results in decreased expression of CCNA2 protein CTD PMID:28341135 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
JBrowse link
G CCNB1 cyclin B1 decreases expression ISO Methamphetamine results in decreased expression of CCNB1 mRNA; Methamphetamine results in decreased expression of CCNB1 protein CTD PMID:28341135 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CCNB2 cyclin B2 decreases expression EXP
ISO
Methamphetamine results in decreased expression of CCNB2 mRNA
Methamphetamine results in decreased expression of CCNB2 mRNA; Methamphetamine results in decreased expression of CCNB2 protein
CTD PMID:25290377 PMID:28341135 NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
JBrowse link
G CCND1 cyclin D1 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of CCND1 mRNA
Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCND1 mRNA]
CTD PMID:19149911 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCNE1 cyclin E1 decreases expression ISO Methamphetamine results in decreased expression of CCNE1 protein CTD PMID:28341135 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CCNL1 cyclin L1 increases expression ISO Methamphetamine results in increased expression of CCNL1 mRNA CTD PMID:19564919 NCBI chr 3:157,143,121...157,160,180
Ensembl chr 3:157,146,508...157,160,760
JBrowse link
G CCNL2 cyclin L2 increases expression ISO Methamphetamine results in increased expression of CCNL2 mRNA CTD PMID:26307267 NCBI chr 1:1,385,711...1,399,336
Ensembl chr 1:1,385,711...1,399,335
JBrowse link
G CCR2 C-C motif chemokine receptor 2 increases response to substance
increases methylation
increases expression
ISO CCR2 protein results in increased susceptibility to Methamphetamine
Methamphetamine results in increased methylation of CCR2 promoter
Methamphetamine results in increased expression of CCR2 mRNA
CTD PMID:20624155 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CCR5 C-C motif chemokine receptor 5 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of CCR5 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CCR5 mRNA
CTD PMID:19564919 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,854...46,376,206
JBrowse link
G CCR7 C-C motif chemokine receptor 7 decreases expression ISO Methamphetamine results in decreased expression of CCR7 mRNA CTD PMID:26307267 NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 decreases expression ISO Methamphetamine results in decreased expression of CCT2 protein CTD PMID:19826936 NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 decreases expression ISO Methamphetamine results in decreased expression of CCT5 protein CTD PMID:19826936 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
JBrowse link
G CD151 CD151 molecule (Raph blood group) increases expression ISO Methamphetamine results in increased expression of CD151 mRNA CTD PMID:32035215 NCBI chr11:832,952...838,835
Ensembl chr11:832,887...839,831
JBrowse link
G CD177 CD177 molecule increases expression EXP Methamphetamine results in increased expression of CD177 mRNA CTD PMID:25290377 NCBI chr19:43,353,686...43,366,063
Ensembl chr19:43,353,686...43,363,172
JBrowse link
G CD3D CD3d molecule increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of CD3D protein
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein]
CTD PMID:29705343 NCBI chr11:118,338,954...118,342,705
Ensembl chr11:118,339,075...118,342,705
JBrowse link
G CD55 CD55 molecule (Cromer blood group) affects response to substance EXP CD55 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 1:207,321,674...207,360,966
Ensembl chr 1:207,321,532...207,386,804
JBrowse link
G CDC42EP3 CDC42 effector protein 3 increases expression ISO Methamphetamine results in increased expression of CDC42EP3 mRNA CTD PMID:19564919 NCBI chr 2:37,641,944...37,672,949
Ensembl chr 2:37,641,882...37,738,468
JBrowse link
G CDC45 cell division cycle 45 decreases expression EXP Methamphetamine results in decreased expression of CDC45 mRNA CTD PMID:25290377 NCBI chr22:19,479,294...19,520,612
Ensembl chr22:19,479,457...19,520,612
JBrowse link
G CDCA3 cell division cycle associated 3 decreases expression ISO Methamphetamine results in decreased expression of CDCA3 mRNA; Methamphetamine results in decreased expression of CDCA3 protein CTD PMID:28341135 NCBI chr12:6,844,795...6,852,079
Ensembl chr12:6,844,793...6,851,292
JBrowse link
G CDCA7 cell division cycle associated 7 decreases expression ISO Methamphetamine results in decreased expression of CDCA7 mRNA CTD PMID:26307267 NCBI chr 2:173,354,861...173,368,997
Ensembl chr 2:173,354,820...173,368,997
JBrowse link
G CDCA8 cell division cycle associated 8 decreases expression EXP Methamphetamine results in decreased expression of CDCA8 mRNA CTD PMID:25290377 NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719
JBrowse link
G CDH13 cadherin 13 affects response to substance EXP CDH13 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr16:82,626,823...83,800,640
Ensembl chr16:82,626,965...83,800,640
JBrowse link
G CDH5 cadherin 5 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CDH5 mRNA
Luteolin inhibits the reaction [Methamphetamine results in increased expression of CDH5 mRNA]
CTD PMID:32035215 NCBI chr16:66,366,657...66,404,784
Ensembl chr16:66,366,622...66,404,784
JBrowse link
G CDHR2 cadherin related family member 2 decreases expression ISO Methamphetamine results in decreased expression of CDHR2 mRNA CTD PMID:19564919 NCBI chr 5:176,542,511...176,595,974
Ensembl chr 5:176,542,511...176,595,974
JBrowse link
G CDK1 cyclin dependent kinase 1 increases expression
decreases expression
ISO Methamphetamine results in increased expression of CDK1 mRNA
Methamphetamine results in decreased expression of CDK1 mRNA; Methamphetamine results in decreased expression of CDK1 protein
CTD PMID:15644446 PMID:28341135 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CDK10 cyclin dependent kinase 10 decreases expression ISO Methamphetamine results in decreased expression of CDK10 mRNA CTD PMID:19564919 NCBI chr16:89,686,612...89,696,354
Ensembl chr16:89,680,737...89,696,354
JBrowse link
G CDK5 cyclin dependent kinase 5 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of CDK5 protein
SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of CDK5 protein]
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]
CTD PMID:29705343 PMID:32278788 NCBI chr 7:151,053,815...151,057,897
Ensembl chr 7:151,053,815...151,057,897
JBrowse link
G CDK6 cyclin dependent kinase 6 increases expression ISO Methamphetamine results in increased expression of CDK6 mRNA CTD PMID:19564919 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573
JBrowse link
G CDK9 cyclin dependent kinase 9 increases expression ISO Methamphetamine results in increased expression of CDK9 mRNA CTD PMID:26307267 NCBI chr 9:127,786,034...127,790,792
Ensembl chr 9:127,785,679...127,790,792
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CDKN1A mRNA
Methamphetamine results in increased expression of CDKN1A mRNA
CTD PMID:19564919 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B increases expression ISO Methamphetamine results in increased expression of CDKN2B mRNA CTD PMID:15644446 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CDPF1 cysteine rich DPF motif domain containing 1 decreases expression ISO Methamphetamine results in decreased expression of CDPF1 mRNA CTD PMID:19564919 NCBI chr22:46,244,013...46,250,780
Ensembl chr22:46,244,011...46,250,311
JBrowse link
G CDR2 cerebellar degeneration related protein 2 increases expression ISO Methamphetamine results in increased expression of CDR2 mRNA CTD PMID:19564919 NCBI chr16:22,345,936...22,374,619
Ensembl chr16:22,345,936...22,437,165
JBrowse link
G CDS2 CDP-diacylglycerol synthase 2 increases expression ISO Methamphetamine results in increased expression of CDS2 mRNA CTD PMID:26307267 NCBI chr20:5,126,844...5,197,887
Ensembl chr20:5,126,879...5,197,887
JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of CEBPB mRNA; Methamphetamine results in increased expression of CEBPB protein
CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]
[Methamphetamine co-treated with SCH 23390] results in increased expression of CEBPB mRNA; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein]
CTD PMID:19564919 PMID:31059759 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CELA1 chymotrypsin like elastase 1 decreases expression ISO Methamphetamine results in decreased expression of CELA1 mRNA CTD PMID:26307267 NCBI chr12:51,328,442...51,346,679
Ensembl chr12:51,328,442...51,346,679
JBrowse link
G CENPCP1 centromere protein C pseudogene 1 affects response to substance EXP CENPCP1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr12:89,499,942...89,503,082
Ensembl chr12:89,500,093...89,502,670
JBrowse link
G CENPH centromere protein H decreases expression ISO Methamphetamine results in decreased expression of CENPH mRNA CTD PMID:28341135 NCBI chr 5:69,189,583...69,210,357
Ensembl chr 5:69,189,574...69,210,357
JBrowse link
G CENPQ centromere protein Q decreases expression ISO Methamphetamine results in decreased expression of CENPQ mRNA CTD PMID:28341135 NCBI chr 6:49,463,327...49,493,107
Ensembl chr 6:49,463,370...49,493,107
JBrowse link
G CENPW centromere protein W decreases expression ISO Methamphetamine results in decreased expression of CENPW mRNA CTD PMID:28341135 NCBI chr 6:126,339,696...126,483,320
Ensembl chr 6:126,340,115...126,348,875
JBrowse link
G CEP104 centrosomal protein 104 multiple interactions
affects expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CEP104 mRNA
Methamphetamine affects the expression of CEP104 mRNA
CTD PMID:19564919 NCBI chr 1:3,812,086...3,857,233
Ensembl chr 1:3,812,086...3,857,396
JBrowse link
G CEP55 centrosomal protein 55 decreases expression EXP Methamphetamine results in decreased expression of CEP55 mRNA CTD PMID:25290377 NCBI chr10:93,496,612...93,529,094
Ensembl chr10:93,496,612...93,529,092
JBrowse link
G CEP72 centrosomal protein 72 decreases expression ISO Methamphetamine results in decreased expression of CEP72 mRNA CTD PMID:28341135 NCBI chr 5:612,340...668,744
Ensembl chr 5:612,340...667,168
JBrowse link
G CEP95 centrosomal protein 95 decreases expression ISO Methamphetamine results in decreased expression of CEP95 mRNA CTD PMID:19564919 NCBI chr17:64,506,760...64,537,951
Ensembl chr17:64,506,865...64,542,461
JBrowse link
G CERT1 ceramide transporter 1 increases expression ISO Methamphetamine results in increased expression of CERT1 mRNA CTD PMID:19564919 NCBI chr 5:75,368,486...75,511,981
Ensembl chr 5:75,356,345...75,512,138
JBrowse link
G CGGBP1 CGG triplet repeat binding protein 1 increases expression ISO Methamphetamine results in increased expression of CGGBP1 mRNA CTD PMID:19564919 NCBI chr 3:88,051,950...88,149,870
Ensembl chr 3:88,051,944...88,149,885
JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 increases expression ISO Methamphetamine results in increased expression of CHAC1 mRNA CTD PMID:28619521 NCBI chr15:40,942,137...40,956,518
Ensembl chr15:40,952,962...40,956,512
JBrowse link
G CHAT choline O-acetyltransferase decreases activity EXP Methamphetamine results in decreased activity of CHAT protein CTD PMID:10089005 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942
JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of CHD4 promoter
Methamphetamine results in increased expression of CHD4 mRNA
CTD PMID:26307267 NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524
JBrowse link
G CHERP calcium homeostasis endoplasmic reticulum protein increases expression ISO Methamphetamine results in increased expression of CHERP mRNA CTD PMID:26307267 NCBI chr19:16,517,894...16,542,437
Ensembl chr19:16,517,894...16,542,437
JBrowse link
G CHKB choline kinase beta increases expression ISO Methamphetamine results in increased expression of CHKB mRNA CTD PMID:26307267 NCBI chr22:50,578,963...50,582,849
Ensembl chr22:50,578,959...50,601,455
JBrowse link
G CHORDC1 cysteine and histidine rich domain containing 1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CHORDC1 mRNA
Methamphetamine results in increased expression of CHORDC1 mRNA
CTD PMID:19564919 NCBI chr11:90,200,429...90,223,082
Ensembl chr11:90,200,429...90,223,077
JBrowse link
G CHRNB1 cholinergic receptor nicotinic beta 1 subunit increases expression ISO Methamphetamine results in increased expression of CHRNB1 mRNA CTD PMID:19564919 NCBI chr17:7,445,061...7,457,710
Ensembl chr17:7,445,061...7,457,710
JBrowse link
G CHRNE cholinergic receptor nicotinic epsilon subunit multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CHRNE mRNA
Methamphetamine results in increased expression of CHRNE mRNA
CTD PMID:19564919 NCBI chr17:4,897,771...4,905,019
Ensembl chr17:4,897,771...4,934,438
JBrowse link
G CHTF18 chromosome transmission fidelity factor 18 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CHTF18 mRNA
Methamphetamine results in decreased expression of CHTF18 mRNA
CTD PMID:19564919 NCBI chr16:788,620...798,074
Ensembl chr16:788,046...800,737
JBrowse link
G CIC capicua transcriptional repressor increases expression ISO Methamphetamine results in increased expression of CIC mRNA CTD PMID:26307267 NCBI chr19:42,268,530...42,295,796
Ensembl chr19:42,268,537...42,295,797
JBrowse link
G CIDEA cell death inducing DFFA like effector a increases expression ISO Methamphetamine results in increased expression of CIDEA mRNA; Methamphetamine results in increased expression of CIDEA protein CTD PMID:28341135 NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595
JBrowse link
G CIRBP cold inducible RNA binding protein decreases expression ISO Methamphetamine results in decreased expression of CIRBP mRNA CTD PMID:19564919 NCBI chr19:1,269,332...1,274,880
Ensembl chr19:1,259,384...1,274,880
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 increases expression ISO Methamphetamine results in increased expression of CITED2 mRNA CTD PMID:19564919 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
JBrowse link
G CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CITED4 mRNA
Methamphetamine results in decreased expression of CITED4 mRNA
CTD PMID:19564919 NCBI chr 1:40,861,054...40,862,363
Ensembl chr 1:40,861,054...40,862,363
JBrowse link
G CKAP2 cytoskeleton associated protein 2 decreases expression ISO Methamphetamine results in decreased expression of CKAP2 mRNA CTD PMID:28341135 NCBI chr13:52,455,429...52,476,627
Ensembl chr13:52,455,429...52,476,628
JBrowse link
G CKB creatine kinase B increases expression ISO Methamphetamine results in increased expression of CKB protein CTD PMID:19826936 NCBI chr14:103,519,667...103,522,833
Ensembl chr14:103,519,667...103,522,833
JBrowse link
G CLASRP CLK4 associating serine/arginine rich protein increases expression
decreases expression
ISO Methamphetamine results in increased expression of SFRS16 mRNA
Methamphetamine results in decreased expression of CLASRP mRNA
CTD PMID:26307267 PMID:32035215 NCBI chr19:45,039,045...45,070,956
Ensembl chr19:45,039,045...45,070,956
JBrowse link
G CLCN6 chloride voltage-gated channel 6 increases expression ISO Methamphetamine results in increased expression of CLCN6 mRNA CTD PMID:26307267 NCBI chr 1:11,806,191...11,843,130
Ensembl chr 1:11,806,096...11,848,079
JBrowse link
G CLCNKB chloride voltage-gated channel Kb decreases expression
affects methylation
ISO Methamphetamine results in decreased expression of CLCNKB mRNA
Methamphetamine affects the methylation of CLCNKB promoter
CTD PMID:26307267 NCBI chr 1:16,043,782...16,057,326
Ensembl chr 1:16,040,252...16,057,311
JBrowse link
G CLDN5 claudin 5 decreases expression ISO Methamphetamine results in decreased expression of CLDN5 mRNA CTD PMID:19564919 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545
JBrowse link
G CLEC4E C-type lectin domain family 4 member E decreases expression ISO Methamphetamine results in decreased expression of CLEC4E mRNA CTD PMID:26307267 NCBI chr12:8,533,305...8,541,327
Ensembl chr12:8,533,305...8,540,905
JBrowse link
G CLIC4 chloride intracellular channel 4 increases expression ISO Methamphetamine results in increased expression of CLIC4 mRNA CTD PMID:19149911 NCBI chr 1:24,745,447...24,844,321
Ensembl chr 1:24,745,382...24,844,321
JBrowse link
G CLIP1 CAP-Gly domain containing linker protein 1 increases expression ISO Methamphetamine results in increased expression of CLIP1 mRNA CTD PMID:19564919 PMID:26307267 NCBI chr12:122,271,432...122,422,956
Ensembl chr12:122,271,432...122,422,669
JBrowse link
G CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression ISO Methamphetamine results in increased expression of CLPX mRNA CTD PMID:19149911 NCBI chr15:65,148,219...65,185,374
Ensembl chr15:65,148,219...65,185,342
JBrowse link
G CLUH clustered mitochondria homolog increases expression ISO Methamphetamine results in increased expression of CLUH mRNA CTD PMID:26307267 NCBI chr17:2,689,387...2,712,020
Ensembl chr17:2,689,386...2,712,663
JBrowse link
G CLVS2 clavesin 2 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CLVS2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CLVS2 mRNA
CTD PMID:19564919 NCBI chr 6:122,996,235...123,072,925
Ensembl chr 6:122,996,235...123,072,925
JBrowse link
G CMTM3 CKLF like MARVEL transmembrane domain containing 3 decreases methylation ISO Methamphetamine results in decreased methylation of CMTM3 promoter CTD PMID:26307267 NCBI chr16:66,603,996...66,613,892
Ensembl chr16:66,603,874...66,613,892
JBrowse link
G CMTM8 CKLF like MARVEL transmembrane domain containing 8 decreases expression ISO Methamphetamine results in decreased expression of CMTM8 mRNA CTD PMID:19564919 NCBI chr 3:32,238,680...32,370,321
Ensembl chr 3:32,238,679...32,370,321
JBrowse link
G CNOT6L CCR4-NOT transcription complex subunit 6 like increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CNOT6L mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CNOT6L mRNA
CTD PMID:19564919 NCBI chr 4:77,713,387...77,820,269
Ensembl chr 4:77,713,387...77,819,615
JBrowse link
G CNR1 cannabinoid receptor 1 affects response to substance ISO CNR1 protein affects the susceptibility to Methamphetamine CTD PMID:17953657 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
JBrowse link
G CNTFR ciliary neurotrophic factor receptor increases expression ISO Methamphetamine results in increased expression of CNTFR mRNA CTD PMID:26307267 NCBI chr 9:34,551,432...34,590,386
Ensembl chr 9:34,551,432...34,590,140
JBrowse link
G CNTN2 contactin 2 decreases expression ISO Methamphetamine results in decreased expression of CNTN2 mRNA CTD PMID:19564919 NCBI chr 1:205,042,937...205,078,289
Ensembl chr 1:205,042,937...205,078,289
JBrowse link
G CNTNAP5 contactin associated protein family member 5 decreases expression ISO Methamphetamine results in decreased expression of CNTNAP5A mRNA CTD PMID:26307267 NCBI chr 2:124,025,287...124,921,219
Ensembl chr 2:124,025,287...124,921,219
JBrowse link
G COL10A1 collagen type X alpha 1 chain increases expression ISO Methamphetamine results in increased expression of COL10A1 mRNA CTD PMID:28341135 NCBI chr 6:116,118,909...116,219,937
Ensembl chr 6:116,118,909...116,158,747
JBrowse link
G COL25A1 collagen type XXV alpha 1 chain decreases expression ISO Methamphetamine results in decreased expression of COL25A1 mRNA CTD PMID:26307267 NCBI chr 4:108,808,725...109,302,737
Ensembl chr 4:108,808,725...109,302,752
JBrowse link
G COL28A1 collagen type XXVIII alpha 1 chain affects response to substance EXP COL28A1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 7:7,338,542...7,542,094
Ensembl chr 7:7,356,203...7,535,873
JBrowse link
G COL3A1 collagen type III alpha 1 chain decreases expression ISO Methamphetamine results in decreased expression of COL3A1 mRNA CTD PMID:19564919 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G COMT catechol-O-methyltransferase increases response to substance
affects response to substance
EXP COMT gene polymorphism results in increased susceptibility to Methamphetamine
COMT gene polymorphism affects the susceptibility to Methamphetamine
CTD PMID:15274053 PMID:19462300 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
JBrowse link
G COPB2 COPI coat complex subunit beta 2 increases expression ISO Methamphetamine results in increased expression of COPB2 mRNA CTD PMID:32035215 NCBI chr 3:139,355,595...139,389,680
Ensembl chr 3:139,353,946...139,389,736
JBrowse link
G COQ10B coenzyme Q10B multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of COQ10B mRNA
Methamphetamine results in increased expression of COQ10B mRNA
CTD PMID:19564919 NCBI chr 2:197,453,552...197,475,310
Ensembl chr 2:197,453,423...197,475,308
JBrowse link
G COQ8A coenzyme Q8A increases expression
decreases methylation
ISO Methamphetamine results in increased expression of COQ8A mRNA
Methamphetamine results in decreased methylation of COQ8A promoter
CTD PMID:26307267 NCBI chr 1:226,939,339...226,987,544
Ensembl chr 1:226,940,286...226,987,544
JBrowse link
G CORO6 coronin 6 increases expression ISO Methamphetamine results in increased expression of CORO6 mRNA CTD PMID:26307267 NCBI chr17:29,614,236...29,622,912
Ensembl chr17:29,614,756...29,622,912
JBrowse link
G COX10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 increases expression ISO Methamphetamine results in increased expression of COX10 mRNA CTD PMID:26307267 NCBI chr17:14,069,504...14,208,677
Ensembl chr17:14,069,490...14,231,736
JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 increases expression ISO Methamphetamine results in increased expression of CPEB3 mRNA CTD PMID:26307267 NCBI chr10:92,046,692...92,291,499
Ensembl chr10:92,046,692...92,291,078
JBrowse link
G CPLX1 complexin 1 increases expression ISO Methamphetamine results in increased expression of CPLX1 protein CTD PMID:19826936 NCBI chr 4:784,957...826,129
Ensembl chr 4:784,957...826,129
JBrowse link
G CPLX2 complexin 2 increases expression ISO Methamphetamine results in increased expression of CPLX2 protein CTD PMID:19826936 NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,310...175,884,021
JBrowse link
G CPTP ceramide-1-phosphate transfer protein decreases methylation ISO Methamphetamine results in decreased methylation of CPTP promoter CTD PMID:26307267 NCBI chr 1:1,324,757...1,328,896
Ensembl chr 1:1,324,756...1,328,896
JBrowse link
G CPZ carboxypeptidase Z increases expression ISO Methamphetamine results in increased expression of CPZ mRNA CTD PMID:15644446 NCBI chr 4:8,592,765...8,619,752
Ensembl chr 4:8,592,660...8,619,759
JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 decreases expression ISO Methamphetamine results in decreased expression of CRABP1 mRNA CTD PMID:32035215 NCBI chr15:78,340,353...78,348,225
Ensembl chr15:78,340,353...78,348,225
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions
increases expression
ISO
EXP
Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 protein]
Methamphetamine results in increased expression of CREB1 mRNA; Methamphetamine results in increased expression of CREB1 protein
CTD PMID:30742852 PMID:33421459 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CRELD2 cysteine rich with EGF like domains 2 increases expression ISO Methamphetamine results in increased expression of CRELD2 mRNA CTD PMID:19564919 NCBI chr22:49,918,634...49,927,540
Ensembl chr22:49,918,167...49,927,540
JBrowse link
G CREM cAMP responsive element modulator multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CREM mRNA
Methamphetamine results in increased expression of CREM mRNA
CTD PMID:19564919 NCBI chr10:35,126,841...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CRH corticotropin releasing hormone multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CRH mRNA
Methamphetamine results in increased expression of CRH mRNA
CTD PMID:19564919 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 multiple interactions ISO [CP 154526 binds to and results in decreased activity of CRHR1 protein] which results in decreased susceptibility to Methamphetamine CTD PMID:17119930 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,280...45,835,828
JBrowse link
G CRISPLD1 cysteine rich secretory protein LCCL domain containing 1 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CRISPLD1 mRNA
Methamphetamine results in decreased expression of CRISPLD1 mRNA
CTD PMID:19564919 NCBI chr 8:74,984,505...75,034,558
Ensembl chr 8:74,984,505...75,034,558
JBrowse link
G CRK CRK proto-oncogene, adaptor protein decreases expression ISO Methamphetamine results in decreased expression of CRK protein CTD PMID:19826936 NCBI chr17:1,420,693...1,456,232
Ensembl chr17:1,420,689...1,463,162
JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein increases expression ISO Methamphetamine results in increased expression of CRKL mRNA CTD PMID:19564919 NCBI chr22:20,917,407...20,953,747
Ensembl chr22:20,917,407...20,953,747
JBrowse link
G CRTC2 CREB regulated transcription coactivator 2 increases expression ISO Methamphetamine results in increased expression of CRTC2 mRNA CTD PMID:26307267 NCBI chr 1:153,947,675...153,958,643
Ensembl chr 1:153,947,669...153,958,615
JBrowse link
G CRY1 cryptochrome circadian regulator 1 decreases expression ISO Methamphetamine results in decreased expression of CRY1 mRNA CTD PMID:19149911 NCBI chr12:106,991,364...107,093,872
Ensembl chr12:106,991,364...107,093,549
JBrowse link
G CRYAB crystallin alpha B increases expression
multiple interactions
ISO Methamphetamine results in increased expression of CRYAB mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CRYAB mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CRYAB mRNA]
CTD PMID:19564919 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G CRYM crystallin mu increases expression ISO Methamphetamine results in increased expression of CRYM protein CTD PMID:19826936 NCBI chr16:21,258,521...21,303,062
Ensembl chr16:21,238,874...21,303,083
JBrowse link
G CS citrate synthase increases expression ISO Methamphetamine results in increased expression of CS mRNA CTD PMID:19149911 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391
JBrowse link
G CSF1 colony stimulating factor 1 increases expression ISO Methamphetamine results in increased expression of CSF1 mRNA CTD PMID:26307267 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992
JBrowse link
G CSF1R colony stimulating factor 1 receptor increases expression ISO Methamphetamine results in increased expression of CSF1R mRNA CTD PMID:32035215 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CSMD1 CUB and Sushi multiple domains 1 affects response to substance EXP CSMD1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 8:2,935,353...4,995,035
Ensembl chr 8:2,935,353...4,994,972
JBrowse link
G CSN1S1 casein alpha s1 increases expression ISO Methamphetamine results in increased expression of CSN1S1 mRNA CTD PMID:28341135 NCBI chr 4:69,931,062...69,946,574
Ensembl chr 4:69,931,068...69,946,574
JBrowse link
G CSRP2 cysteine and glycine rich protein 2 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of CSRP2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CSRP2 mRNA
CTD PMID:19564919 NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
JBrowse link
G CST11 cystatin 11 increases methylation ISO Methamphetamine results in increased methylation of CST11 promoter CTD PMID:26307267 NCBI chr20:23,450,412...23,452,876
Ensembl chr20:23,450,403...23,452,876
JBrowse link
G CSTB cystatin B affects expression ISO Methamphetamine affects the expression of CSTB protein CTD PMID:17904249 NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330
JBrowse link
G CTBP2 C-terminal binding protein 2 decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of CTBP2 promoter
Methamphetamine results in increased expression of CTBP2 mRNA
CTD PMID:26307267 NCBI chr10:124,984,317...125,161,039
Ensembl chr10:124,984,317...125,161,170
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions
increases expression
ISO Lithium inhibits the reaction [Methamphetamine results in increased expression of CTNNB1 mRNA] CTD PMID:19149911 PMID:32035215 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CTRL chymotrypsin like increases expression ISO Methamphetamine results in increased expression of CTRL mRNA CTD PMID:19564919 NCBI chr16:67,929,574...67,931,862
Ensembl chr16:67,927,640...67,932,365
JBrowse link
G CTSD cathepsin D affects localization ISO Methamphetamine affects the localization of CTSD protein CTD PMID:17105920 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
JBrowse link
G CUBN cubilin affects response to substance EXP CUBN gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr10:16,823,966...17,130,492
Ensembl chr10:16,823,966...17,129,811
JBrowse link
G CUEDC1 CUE domain containing 1 increases expression ISO Methamphetamine results in increased expression of CUEDC1 mRNA CTD PMID:26307267 NCBI chr17:57,861,243...57,955,412
Ensembl chr17:57,861,243...57,955,412
JBrowse link
G CUL2 cullin 2 decreases expression ISO Methamphetamine results in decreased expression of CUL2 mRNA CTD PMID:19564919 NCBI chr10:35,008,551...35,126,899
Ensembl chr10:35,008,551...35,090,642
JBrowse link
G CUL9 cullin 9 increases expression ISO Methamphetamine results in increased expression of CUL9 mRNA CTD PMID:26307267 NCBI chr 6:43,182,170...43,224,587
Ensembl chr 6:43,182,184...43,224,587
JBrowse link
G CUX1 cut like homeobox 1 increases expression ISO Methamphetamine results in increased expression of CUX1 mRNA CTD PMID:19564919 NCBI chr 7:101,815,991...102,283,958
Ensembl chr 7:101,815,904...102,283,958
JBrowse link
G CWC25 CWC25 spliceosome associated protein homolog increases expression ISO Methamphetamine results in increased expression of CWC25 mRNA CTD PMID:19564919 NCBI chr17:38,800,441...38,825,325
Ensembl chr17:38,800,441...38,825,355
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 decreases expression ISO Methamphetamine results in decreased expression of CX3CR1 mRNA CTD PMID:19564919 NCBI chr 3:39,263,494...39,281,735
Ensembl chr 3:39,263,495...39,281,735
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 increases expression EXP Methamphetamine results in increased expression of CXCL10 mRNA CTD PMID:25290377 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 multiple interactions
increases expression
ISO Luteolin inhibits the reaction [Methamphetamine results in increased expression of CXCL12 mRNA] CTD PMID:32035215 NCBI chr10:44,292,088...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 increases expression EXP Methamphetamine results in increased expression of CXCL2 mRNA CTD PMID:25290377 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CYB5B cytochrome b5 type B increases expression ISO Methamphetamine results in increased expression of CYB5B mRNA CTD PMID:19149911 NCBI chr16:69,424,619...69,466,264
Ensembl chr16:69,424,619...69,466,264
JBrowse link
G CYBB cytochrome b-245 beta chain multiple interactions ISO CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein] CTD PMID:27565679 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,059...37,813,461
JBrowse link
G CYCS cytochrome c, somatic increases expression ISO Methamphetamine results in increased expression of CYCS mRNA CTD PMID:19149911 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 increases expression ISO Methamphetamine results in increased expression of CYP11A1 mRNA CTD PMID:19149911 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 affects metabolic processing EXP CYP1A2 protein affects the metabolism of Methamphetamine metabolite CTD PMID:16038959 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 multiple interactions
decreases expression
ISO Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of CYP27A1 mRNA] CTD PMID:19149911 NCBI chr 2:218,781,733...218,815,293
Ensembl chr 2:218,781,749...218,815,293
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 affects response to substance
increases metabolic processing
EXP CYP2D4 gene polymorphism affects the susceptibility to Methamphetamine; CYP2D6 protein affects the susceptibility to Methamphetamine
CYP2D6 protein results in increased metabolism of Methamphetamine
CTD PMID:18280655 PMID:20727252 PMID:27320963 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 affects metabolic processing EXP CYP2E1 protein affects the metabolism of Methamphetamine metabolite CTD PMID:16038959 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 affects metabolic processing
multiple interactions
EXP CYP3A4 protein affects the metabolism of Methamphetamine metabolite
[Methamphetamine binds to CYP3A4 promoter] which results in increased expression of CYP3A4 mRNA
CTD PMID:12851153 PMID:16038959 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYTH1 cytohesin 1 increases expression ISO Methamphetamine results in increased expression of CYTH1 mRNA CTD PMID:26307267 NCBI chr17:78,674,048...78,782,273
Ensembl chr17:78,674,048...78,782,297
JBrowse link
G CYYR1 cysteine and tyrosine rich 1 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CYYR1 mRNA
Methamphetamine results in decreased expression of CYYR1 mRNA
CTD PMID:19564919 NCBI chr21:26,466,216...26,573,286
Ensembl chr21:26,466,209...26,573,286
JBrowse link
G CZIB CXXC motif containing zinc binding protein decreases expression ISO Methamphetamine results in decreased expression of CZIB mRNA CTD PMID:19564919 NCBI chr 1:53,214,099...53,220,634
Ensembl chr 1:53,214,099...53,220,634
JBrowse link
G DAD1 defender against cell death 1 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of DAD1 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DAD1 mRNA]
CTD PMID:19564919 NCBI chr14:22,564,907...22,589,224
Ensembl chr14:22,564,907...22,589,224
JBrowse link
G DBH dopamine beta-hydroxylase decreases expression ISO Methamphetamine results in decreased expression of DBH protein CTD PMID:28661099 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
JBrowse link
G DBP D-box binding PAR bZIP transcription factor increases expression ISO Methamphetamine results in increased expression of DBP mRNA CTD PMID:26307267 NCBI chr19:48,630,030...48,637,379
Ensembl chr19:48,630,030...48,637,379
JBrowse link
G DCSTAMP dendrocyte expressed seven transmembrane protein affects response to substance EXP DCSTAMP gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 8:104,339,087...104,356,874
Ensembl chr 8:104,339,087...104,356,689
JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 affects expression ISO Methamphetamine affects the expression of DDAH1 protein CTD PMID:17904249 NCBI chr 1:85,318,485...85,578,274
Ensembl chr 1:85,318,481...85,578,363
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression
ISO
EXP
[Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT3 mRNA; Melatonin inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]
ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]
Methamphetamine results in increased expression of DDIT3 mRNA; Methamphetamine results in increased expression of DDIT3 protein
CTD PMID:15644446 PMID:19564919 PMID:27323860 PMID:28070110 PMID:28619521 PMID:32203791 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DDIT4 DNA damage inducible transcript 4 multiple interactions
increases expression
increases response to substance
ISO
EXP
[Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT4 mRNA; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of PARP1 protein modified form]
DDIT4 protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein]
Methamphetamine results in increased expression of DDIT4 mRNA; Methamphetamine results in increased expression of DDIT4 protein
DDIT4 protein results in increased susceptibility to Methamphetamine
CTD PMID:19564919 PMID:26825372 PMID:31059759 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
JBrowse link
G DDT D-dopachrome tautomerase affects expression ISO Methamphetamine affects the expression of DDT protein CTD PMID:17904249 NCBI chr22:23,971,370...23,979,828
Ensembl chr22:23,971,365...23,979,828
JBrowse link
G DDX10 DEAD-box helicase 10 increases expression ISO Methamphetamine results in increased expression of DDX10 mRNA CTD PMID:19149911 NCBI chr11:108,665,069...108,940,927
Ensembl chr11:108,665,069...108,940,927
JBrowse link
G DDX17 DEAD-box helicase 17 increases expression ISO Methamphetamine results in increased expression of DDX17 mRNA CTD PMID:26307267 NCBI chr22:38,483,438...38,506,311
Ensembl chr22:38,483,438...38,507,660
JBrowse link
G DDX21 DExD-box helicase 21 multiple interactions
decreases expression
ISO Lithium inhibits the reaction [Methamphetamine results in decreased expression of DDX21 mRNA] CTD PMID:19149911 NCBI chr10:68,956,131...68,985,068
Ensembl chr10:68,956,170...68,985,068
JBrowse link
G DDX52 DExD-box helicase 52 decreases expression ISO Methamphetamine results in decreased expression of DDX52 mRNA CTD PMID:19564919 NCBI chr17:37,609,739...37,643,448
Ensembl chr17:37,609,739...37,643,446
JBrowse link
G DDX58 DExD/H-box helicase 58 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of DDX58 mRNA
Methamphetamine results in decreased expression of DDX58 mRNA
CTD PMID:19564919 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208
JBrowse link
G DEAF1 DEAF1 transcription factor increases expression ISO Methamphetamine results in increased expression of DEAF1 mRNA CTD PMID:26307267 NCBI chr11:644,220...707,083
Ensembl chr11:644,233...707,118
JBrowse link
G DENND5A DENN domain containing 5A increases expression ISO Methamphetamine results in increased expression of DENND5A mRNA CTD PMID:26307267 NCBI chr11:9,138,825...9,265,350
Ensembl chr11:9,138,825...9,265,959
JBrowse link
G DEPDC1 DEP domain containing 1 decreases expression ISO Methamphetamine results in decreased expression of DEPDC1 mRNA CTD PMID:28341135 NCBI chr 1:68,474,152...68,497,082
Ensembl chr 1:68,474,152...68,497,221
JBrowse link
G DGKB diacylglycerol kinase beta decreases expression ISO Methamphetamine results in decreased expression of DGKB mRNA CTD PMID:32035215 NCBI chr 7:14,145,049...14,974,858
Ensembl chr 7:14,145,049...14,974,777
JBrowse link
G DGKG diacylglycerol kinase gamma increases expression ISO Methamphetamine results in increased expression of DGKG mRNA CTD PMID:26307267 NCBI chr 3:186,147,201...186,362,234
Ensembl chr 3:186,105,668...186,362,234
JBrowse link
G DGKH diacylglycerol kinase eta increases expression ISO Methamphetamine results in increased expression of DGKH mRNA CTD PMID:26307267 NCBI chr13:42,040,070...42,256,584
Ensembl chr13:42,040,036...42,256,578
JBrowse link
G DGKZ diacylglycerol kinase zeta increases expression ISO Methamphetamine results in increased expression of DGKZ mRNA CTD PMID:26307267 NCBI chr11:46,332,926...46,380,554
Ensembl chr11:46,332,905...46,380,554
JBrowse link
G DHX16 DEAH-box helicase 16 increases expression ISO Methamphetamine results in increased expression of DHX16 mRNA CTD PMID:26307267 NCBI chr 6:30,653,127...30,673,006
Ensembl chr 6:30,653,119...30,673,006
JBrowse link
G DIAPH3 diaphanous related formin 3 decreases expression ISO Methamphetamine results in decreased expression of DIAPH3 mRNA CTD PMID:28341135 NCBI chr13:59,665,583...60,163,928
Ensembl chr13:59,665,583...60,163,928
JBrowse link
G DICER1 dicer 1, ribonuclease III increases methylation ISO Methamphetamine results in increased methylation of DICER1 promoter CTD PMID:26307267 NCBI chr14:95,086,228...95,158,263
Ensembl chr14:95,086,228...95,158,010
JBrowse link
G DIO2 iodothyronine deiodinase 2 increases expression ISO Methamphetamine results in increased expression of DIO2 mRNA CTD PMID:19149911 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757
JBrowse link
G DIPK1A divergent protein kinase domain 1A decreases expression ISO Methamphetamine results in decreased expression of DIPK1A mRNA CTD PMID:19564919 NCBI chr 1:92,832,729...92,961,462
Ensembl chr 1:92,832,737...92,961,522
JBrowse link
G DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease increases expression ISO Methamphetamine results in increased expression of DIS3 mRNA CTD PMID:19564919 NCBI chr13:72,752,169...72,781,900
Ensembl chr13:72,752,169...72,782,096
JBrowse link
G DIS3L DIS3 like exosome 3'-5' exoribonuclease increases expression ISO Methamphetamine results in increased expression of DIS3L mRNA CTD PMID:26307267 NCBI chr15:66,293,309...66,333,898
Ensembl chr15:66,293,217...66,333,898
JBrowse link
G DIS3L2 DIS3 like 3'-5' exoribonuclease 2 increases expression ISO Methamphetamine results in increased expression of DIS3L2 mRNA CTD PMID:32035215 NCBI chr 2:231,961,713...232,344,350
Ensembl chr 2:231,961,245...232,344,350
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 increases expression EXP Methamphetamine results in increased expression of DKK1 mRNA CTD PMID:25290377 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G DLAT dihydrolipoamide S-acetyltransferase decreases expression ISO Methamphetamine results in decreased expression of DLAT protein CTD PMID:19826936 NCBI chr11:112,025,408...112,064,404
Ensembl chr11:112,025,408...112,064,404
JBrowse link
G DLD dihydrolipoamide dehydrogenase increases expression ISO Methamphetamine results in increased expression of DLD protein CTD PMID:19826936 NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of DLG4 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of DLG4 protein]
CTD PMID:33421459 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,841
JBrowse link
G DLGAP5 DLG associated protein 5 decreases expression EXP Methamphetamine results in decreased expression of DLGAP5 mRNA CTD PMID:25290377 NCBI chr14:55,148,130...55,191,585
Ensembl chr14:55,148,112...55,191,608
JBrowse link
G DLST dihydrolipoamide S-succinyltransferase decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of DLST mRNA; Methamphetamine results in decreased expression of DLST protein
Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of DLST mRNA]
CTD PMID:19149911 PMID:19826936 NCBI chr14:74,881,913...74,903,743
Ensembl chr14:74,881,891...74,903,743
JBrowse link
G DMD dystrophin increases expression ISO Methamphetamine results in increased expression of DMD mRNA CTD PMID:26307267 NCBI chr  X:31,119,219...33,339,460
Ensembl chr  X:31,097,677...33,339,609
JBrowse link
G DMKN dermokine increases expression
decreases expression
ISO Methamphetamine results in increased expression of DMKN mRNA
Methamphetamine results in decreased expression of DMKN mRNA
CTD PMID:19564919 PMID:32035215 NCBI chr19:35,497,220...35,513,678
Ensembl chr19:35,497,220...35,513,658
JBrowse link
G DMPK DM1 protein kinase increases expression ISO Methamphetamine results in increased expression of DMPK mRNA CTD PMID:26307267 NCBI chr19:45,769,709...45,782,490
Ensembl chr19:45,769,709...45,782,552
JBrowse link
G DMWD DM1 locus, WD repeat containing increases expression ISO Methamphetamine results in increased expression of DMWD mRNA CTD PMID:26307267 NCBI chr19:45,782,947...45,792,845
Ensembl chr19:45,782,947...45,792,845
JBrowse link
G DNAAF2 dynein axonemal assembly factor 2 increases expression ISO Methamphetamine results in increased expression of DNAAF2 mRNA CTD PMID:19564919 NCBI chr14:49,625,174...49,635,244
Ensembl chr14:49,625,174...49,635,244
JBrowse link
G DNAH1 dynein axonemal heavy chain 1 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of DNAH1 mRNA
Methamphetamine results in decreased expression of DNAH1 mRNA
CTD PMID:19564919 NCBI chr 3:52,313,010...52,400,497
Ensembl chr 3:52,316,319...52,400,492
JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJA1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJA1 mRNA] CTD PMID:19564919 NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907
JBrowse link
G DNAJA4 DnaJ heat shock protein family (Hsp40) member A4 increases expression ISO Methamphetamine results in increased expression of DNAJA4 mRNA CTD PMID:19564919 NCBI chr15:78,264,145...78,282,191
Ensembl chr15:78,264,086...78,282,196
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB1 mRNA] CTD PMID:19564919 NCBI chr19:14,514,769...14,530,597
Ensembl chr19:14,514,769...14,560,391
JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB4 mRNA
Methamphetamine results in increased expression of DNAJB4 mRNA
CTD PMID:19564919 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964
JBrowse link
G DNAJB5 DnaJ heat shock protein family (Hsp40) member B5 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of DNAJB5 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB5 mRNA]
CTD PMID:19564919 NCBI chr 9:34,989,745...34,998,900
Ensembl chr 9:34,989,641...34,998,900
JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of DNAJC3 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJC3 mRNA]
CTD PMID:19564919 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
JBrowse link
G DNAL4 dynein axonemal light chain 4 decreases expression ISO Methamphetamine results in decreased expression of DNAL4 mRNA CTD PMID:19564919 NCBI chr22:38,778,508...38,794,143
Ensembl chr22:38,778,508...38,794,198
JBrowse link
G DNASE1 deoxyribonuclease 1 increases expression
decreases expression
multiple interactions
ISO Methamphetamine results in increased expression of DNASE1 mRNA
Methamphetamine results in decreased expression of DNASE1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of DNASE1 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr16:3,611,737...3,665,472
Ensembl chr16:3,611,728...3,680,143
JBrowse link
G DNM1 dynamin 1 increases expression ISO Methamphetamine results in increased expression of DNM1 mRNA CTD PMID:26307267 NCBI chr 9:128,203,379...128,255,244
Ensembl chr 9:128,191,655...128,255,248
JBrowse link
G DNMT1 DNA methyltransferase 1 decreases expression
increases expression
ISO Methamphetamine results in decreased expression of DNMT1 mRNA
Methamphetamine results in increased expression of DNMT1 mRNA
CTD PMID:17254711 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G DOC2GP double C2 domain gamma, pseudogene increases expression ISO Methamphetamine results in increased expression of DOC2G mRNA CTD PMID:26307267 NCBI chr11:67,613,524...67,615,664
Ensembl chr11:67,612,651...67,616,257
JBrowse link
G DOCK6 dedicator of cytokinesis 6 increases expression ISO Methamphetamine results in increased expression of DOCK6 mRNA CTD PMID:26307267 NCBI chr19:11,199,295...11,262,524
Ensembl chr19:11,199,295...11,262,524
JBrowse link
G DOK3 docking protein 3 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of DOK3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of DOK3 mRNA
CTD PMID:19564919 NCBI chr 5:177,501,904...177,511,100
Ensembl chr 5:177,501,904...177,511,274
JBrowse link
G DOLK dolichol kinase decreases expression ISO Methamphetamine results in decreased expression of DOLK mRNA CTD PMID:19564919 NCBI chr 9:128,945,530...128,947,603
Ensembl chr 9:128,945,530...128,947,603
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 affects expression ISO Methamphetamine affects the expression of DPYSL2 protein CTD PMID:19826936 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
JBrowse link
G DPYSL3 dihydropyrimidinase like 3 decreases expression ISO Methamphetamine results in decreased expression of DPYSL3 protein CTD PMID:19826936 NCBI chr 5:147,390,808...147,510,068
Ensembl chr 5:147,390,808...147,510,068
JBrowse link
G DPYSL5 dihydropyrimidinase like 5 increases expression ISO Methamphetamine results in increased expression of DPYSL5 protein CTD PMID:19826936 NCBI chr 2:26,847,995...26,950,351
Ensembl chr 2:26,847,747...26,950,351
JBrowse link
G DRD1 dopamine receptor D1 increases expression
decreases expression
multiple interactions
affects activity
increases response to substance
EXP
ISO
Methamphetamine results in increased expression of DRD1 protein
Methamphetamine results in decreased expression of DRD1 protein
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD1 protein]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [SCH 23390 binds to DRD1 protein]
DRD1 protein results in increased susceptibility to Methamphetamine
[SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; bisphenol A promotes the reaction [DRD1 protein results in increased susceptibility to Methamphetamine]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]
CTD PMID:2891082 PMID:11126397 PMID:11701771 PMID:12617968 PMID:18363855 PMID:18489579 PMID:19444617 PMID:19733155 PMID:20340177 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 increases response to substance
decreases expression
multiple interactions
increases activity
affects activity
EXP
ISO
DRD2 gene polymorphism results in increased susceptibility to Methamphetamine
Methamphetamine results in decreased expression of DRD2 protein
[Sulpiride binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Methamphetamine; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]
Methamphetamine results in increased activity of DRD2 protein
Methamphetamine affects the activity of DRD2 protein
DRD2 gene results in increased susceptibility to Methamphetamine
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD2 protein]; [Aripiprazole binds to and results in increased activity of DRD2 protein] which results in increased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [Sulpiride binds to DRD2 protein]
CTD PMID:2891082 PMID:11126397 PMID:11729018 PMID:17327886 PMID:18363855 PMID:18489579 PMID:18555060 PMID:19046384 PMID:19940168 PMID:20340177 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DRD3 dopamine receptor D3 decreases expression
increases activity
EXP
ISO
Methamphetamine results in decreased expression of DRD3 protein
Methamphetamine results in increased activity of DRD3 protein
CTD PMID:19046384 PMID:19940168 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G DRD4 dopamine receptor D4 affects response to substance
multiple interactions
increases response to substance
EXP
ISO
DRD4 gene polymorphism affects the susceptibility to Methamphetamine
[NRA 0160 binds to and results in decreased activity of DRD4 protein] which results in decreased susceptibility to Methamphetamine
DRD4 gene polymorphism results in increased susceptibility to Methamphetamine
CTD PMID:10579464 PMID:15274053 PMID:19462300 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G DSP desmoplakin increases expression ISO Methamphetamine results in increased expression of DSP mRNA CTD PMID:26307267 NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,617...7,586,714
JBrowse link
G DSPP dentin sialophosphoprotein increases expression ISO Methamphetamine results in increased expression of DSPP mRNA CTD PMID:15644446 NCBI chr 4:87,608,529...87,616,873
Ensembl chr 4:87,608,529...87,616,873
JBrowse link
G DST dystonin increases expression ISO Methamphetamine results in increased expression of DST mRNA CTD PMID:26307267 NCBI chr 6:56,457,996...56,954,830
Ensembl chr 6:56,457,987...56,954,830
JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog decreases expression EXP Methamphetamine results in decreased expression of DTL mRNA CTD PMID:25290377 NCBI chr 1:212,035,748...212,105,013
Ensembl chr 1:212,035,553...212,107,400
JBrowse link
G DTX3 deltex E3 ubiquitin ligase 3 increases expression
increases methylation
ISO Methamphetamine results in increased expression of DTX3 mRNA
Methamphetamine results in increased methylation of DTX3 promoter
CTD PMID:26307267 NCBI chr12:57,604,327...57,609,802
Ensembl chr12:57,604,622...57,609,804
JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP1 mRNA; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA] CTD PMID:11701771 PMID:19564919 PMID:26307267 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G DUSP11 dual specificity phosphatase 11 increases expression ISO Methamphetamine results in increased expression of DUSP11 mRNA CTD PMID:19564919 NCBI chr 2:73,762,198...73,780,157
Ensembl chr 2:73,762,184...73,780,157
JBrowse link
G DUSP14 dual specificity phosphatase 14 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP14 mRNA
Methamphetamine results in increased expression of DUSP14 mRNA
CTD PMID:19564919 NCBI chr17:37,488,561...37,513,501
Ensembl chr17:37,489,891...37,513,501
JBrowse link
G DUSP5 dual specificity phosphatase 5 increases expression ISO Methamphetamine results in increased expression of DUSP5 mRNA CTD PMID:19564919 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533
JBrowse link
G DUSP6 dual specificity phosphatase 6 multiple interactions
increases expression
ISO [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA] CTD PMID:11701771 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501
JBrowse link
G DUT deoxyuridine triphosphatase increases expression ISO Methamphetamine results in increased expression of DUT mRNA CTD PMID:19149911 NCBI chr15:48,329,991...48,343,373
Ensembl chr15:48,331,011...48,343,373
JBrowse link
G DUX4 double homeobox 4 decreases expression ISO Methamphetamine results in decreased expression of DUXBL1 mRNA CTD PMID:19564919 NCBI chr 4:190,173,774...190,185,911
Ensembl chr 4:190,173,774...190,185,942
JBrowse link
G DYDC2 DPY30 domain containing 2 increases expression ISO Methamphetamine results in increased expression of DYDC2 mRNA CTD PMID:28341135 NCBI chr10:80,344,745...80,368,073
Ensembl chr10:80,344,745...80,368,073
JBrowse link
G DYSF dysferlin increases expression ISO Methamphetamine results in increased expression of DYSF mRNA CTD PMID:26307267 NCBI chr 2:71,453,154...71,686,763
Ensembl chr 2:71,453,561...71,686,763
JBrowse link
G EBI3 Epstein-Barr virus induced 3 decreases expression ISO Methamphetamine results in decreased expression of EBI3 mRNA CTD PMID:26307267 NCBI chr19:4,229,196...4,237,539
Ensembl chr19:4,229,523...4,237,528
JBrowse link
G ECHDC2 enoyl-CoA hydratase domain containing 2 increases expression ISO Methamphetamine results in increased expression of ECHDC2 mRNA CTD PMID:26307267 NCBI chr 1:52,895,910...52,927,212
Ensembl chr 1:52,895,910...52,927,212
JBrowse link
G ECHDC3 enoyl-CoA hydratase domain containing 3 decreases expression ISO Methamphetamine results in decreased expression of ECHDC3 mRNA CTD PMID:26307267 NCBI chr10:11,742,382...11,764,070
Ensembl chr10:11,742,366...11,764,070
JBrowse link
G ECT2 epithelial cell transforming 2 decreases expression ISO Methamphetamine results in decreased expression of ECT2 mRNA CTD PMID:28341135 NCBI chr 3:172,750,694...172,829,273
Ensembl chr 3:172,750,682...172,821,474
JBrowse link
G EDC4 enhancer of mRNA decapping 4 increases expression ISO Methamphetamine results in increased expression of EDC4 mRNA CTD PMID:26307267 NCBI chr16:67,873,052...67,884,499
Ensembl chr16:67,873,052...67,884,499
JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase decreases methylation ISO Methamphetamine results in decreased methylation of EEF2K promoter CTD PMID:26307267 NCBI chr16:22,206,278...22,288,738
Ensembl chr16:22,206,278...22,288,738
JBrowse link
G EFNB1 ephrin B1 increases expression ISO Methamphetamine results in increased expression of EFNB1 mRNA CTD PMID:19564919 NCBI chr  X:68,829,021...68,842,160
Ensembl chr  X:68,829,021...68,842,160
JBrowse link
G EGFL7 EGF like domain multiple 7 multiple interactions
increases expression
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFL7 mRNA
Methamphetamine results in increased expression of EGFL7 mRNA
Methamphetamine results in decreased expression of EGFL7 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr 9:136,654,753...136,672,678
Ensembl chr 9:136,658,856...136,672,678
JBrowse link
G EGFLAM EGF like, fibronectin type III and laminin G domains decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of EGFLAM mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFLAM mRNA
CTD PMID:19564919 NCBI chr 5:38,258,559...38,465,480
Ensembl chr 5:38,258,409...38,465,480
JBrowse link
G EGR1 early growth response 1 multiple interactions
increases expression
ISO CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]
Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]]
CTD PMID:11754491 PMID:15644446 PMID:19564919 PMID:20184921 PMID:20298714 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EGR2 early growth response 2 increases expression ISO Methamphetamine results in increased expression of EGR2 mRNA CTD PMID:15644446 PMID:19564919 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,919,900
JBrowse link
G EGR4 early growth response 4 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of EGR4 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of EGR4 mRNA
CTD PMID:19564919 NCBI chr 2:73,290,929...73,293,548
Ensembl chr 2:73,290,929...73,293,701
JBrowse link
G EHBP1L1 EH domain binding protein 1 like 1 increases expression ISO Methamphetamine results in increased expression of EHBP1L1 mRNA CTD PMID:26307267 NCBI chr11:65,576,034...65,592,650
Ensembl chr11:65,576,046...65,592,650
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 increases expression ISO Methamphetamine results in increased expression of EHMT2 mRNA CTD PMID:26307267 NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,687
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
increases expression
ISO
EXP
CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of EIF2AK3 protein modified form]
CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]
CTD PMID:27323860 PMID:28070110 PMID:29705343 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,691,518
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
ISO Methamphetamine results in increased phosphorylation of EIF2S1 protein
Melatonin inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein]
CTD PMID:28070110 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP Methamphetamine inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:19054297 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
JBrowse link
G EIF4G2 eukaryotic translation initiation factor 4 gamma 2 increases expression ISO Methamphetamine results in increased expression of EIF4G2 mRNA CTD PMID:10336889 NCBI chr11:10,797,046...10,808,926
Ensembl chr11:10,797,050...10,808,940
JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 increases expression ISO Methamphetamine results in increased expression of ELP1 mRNA CTD PMID:19564919 NCBI chr 9:108,867,517...108,934,135
Ensembl chr 9:108,866,898...108,934,328
JBrowse link
G EML1 EMAP like 1 increases expression ISO Methamphetamine results in increased expression of EML1 mRNA CTD PMID:32035215 NCBI chr14:99,737,722...99,942,060
Ensembl chr14:99,737,693...99,942,060
JBrowse link
G EML2 EMAP like 2 increases expression ISO Methamphetamine results in increased expression of EML2 mRNA CTD PMID:26307267 NCBI chr19:45,609,396...45,645,629
Ensembl chr19:45,606,994...45,645,602
JBrowse link
G EMSY EMSY transcriptional repressor, BRCA2 interacting increases expression ISO Methamphetamine results in increased expression of EMSY mRNA CTD PMID:26307267 NCBI chr11:76,444,928...76,553,031
Ensembl chr11:76,444,923...76,553,025
JBrowse link
G ENO1 enolase 1 decreases expression ISO Methamphetamine results in decreased expression of ENO1 protein CTD PMID:19826936 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G ENO2 enolase 2 increases expression ISO Methamphetamine results in increased expression of ENO2 protein CTD PMID:19826936 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression ISO Methamphetamine results in decreased expression of ENPP1 mRNA CTD PMID:26307267 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155
JBrowse link
G ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 decreases expression ISO Methamphetamine results in decreased expression of ENPP6 mRNA CTD PMID:28619521 NCBI chr 4:184,088,706...184,217,873
Ensembl chr 4:184,088,706...184,221,230
JBrowse link
G EP400 E1A binding protein p400 increases expression ISO Methamphetamine results in increased expression of EP400 mRNA CTD PMID:26307267 NCBI chr12:131,949,942...132,080,460
Ensembl chr12:131,949,942...132,080,460
JBrowse link
G EPAS1 endothelial PAS domain protein 1 increases expression ISO Methamphetamine results in increased expression of EPAS1 mRNA CTD PMID:32035215 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G EPB41L1 erythrocyte membrane protein band 4.1 like 1 decreases methylation ISO Methamphetamine results in decreased methylation of EPB41L1 promoter CTD PMID:26307267 NCBI chr20:36,064,891...36,232,799
Ensembl chr20:36,091,504...36,232,799
JBrowse link
G EPCAM epithelial cell adhesion molecule decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of EPCAM mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EPCAM mRNA
CTD PMID:19564919 NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601
JBrowse link
G EPHX1 epoxide hydrolase 1 increases expression
multiple interactions
increases methylation
ISO Methamphetamine results in increased expression of EPHX1 mRNA; Methamphetamine results in increased expression of EPHX1 protein
EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Methamphetamine promotes the reaction [PRKCD protein modified form binds to EPHX1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of EPHX1 protein]
Methamphetamine results in increased methylation of EPHX1 promoter
CTD PMID:26307267 PMID:31422080 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
JBrowse link
G EPOR erythropoietin receptor decreases expression ISO Methamphetamine results in decreased expression of EPOR mRNA CTD PMID:15644446 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 increases expression
multiple interactions
increases phosphorylation
ISO
EXP
Methamphetamine results in increased expression of ERN1 protein modified form
ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein]
Melatonin inhibits the reaction [Methamphetamine results in increased expression of ERN1 protein modified form]
CTD PMID:27323860 PMID:28070110 NCBI chr17:64,039,142...64,132,469
Ensembl chr17:64,039,080...64,130,819
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ERRFI1 mRNA
Methamphetamine results in increased expression of ERRFI1 mRNA
CTD PMID:19564919 NCBI chr 1:8,011,725...8,026,309
Ensembl chr 1:8,004,404...8,026,309
JBrowse link
G ESR1 estrogen receptor 1 increases response to substance EXP ESR1 gene polymorphism results in increased susceptibility to Methamphetamine CTD PMID:19386276 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G EVC2 EvC ciliary complex subunit 2 increases expression ISO Methamphetamine results in increased expression of EVC2 mRNA CTD PMID:28341135 NCBI chr 4:5,562,408...5,709,548
Ensembl chr 4:5,542,772...5,709,548
JBrowse link
G EXOC7 exocyst complex component 7 decreases expression ISO Methamphetamine results in decreased expression of EXOC7 mRNA CTD PMID:19564919 NCBI chr17:76,081,016...76,103,787
Ensembl chr17:76,081,016...76,121,576
JBrowse link
G F11R F11 receptor multiple interactions
increases expression
ISO Luteolin inhibits the reaction [Methamphetamine results in increased expression of F11R mRNA] CTD PMID:32035215 NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,343
JBrowse link
G F3 coagulation factor III, tissue factor increases methylation ISO Methamphetamine results in increased methylation of F3 promoter CTD PMID:26307267 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FAAH fatty acid amide hydrolase multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of FAAH mRNA
Methamphetamine results in decreased expression of FAAH mRNA
CTD PMID:19564919 NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848
JBrowse link
G FABP3 fatty acid binding protein 3 affects response to substance
increases expression
ISO
EXP
FABP3 affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of FABP3 mRNA
CTD PMID:20181611 PMID:25290377 NCBI chr 1:31,359,595...31,373,618
Ensembl chr 1:31,365,253...31,376,850
JBrowse link
G FABP7 fatty acid binding protein 7 affects expression ISO Methamphetamine affects the expression of FABP7 protein CTD PMID:17904249 NCBI chr 6:122,749,201...122,784,074
Ensembl chr 6:122,779,716...122,784,074
JBrowse link
G FAH fumarylacetoacetate hydrolase decreases expression ISO Methamphetamine results in decreased expression of FAH mRNA CTD PMID:19564919 NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946
JBrowse link
G FAM110A family with sequence similarity 110 member A decreases expression ISO Methamphetamine results in decreased expression of FAM110A mRNA CTD PMID:19564919 NCBI chr20:833,715...846,279
Ensembl chr20:833,715...857,463
JBrowse link
G FAM126B family with sequence similarity 126 member B increases expression
multiple interactions
ISO Methamphetamine results in increased expression of FAM126B mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of FAM126B mRNA
CTD PMID:19564919 NCBI chr 2:200,973,718...201,071,671
Ensembl chr 2:200,973,718...201,071,671
JBrowse link
G FAM193A family with sequence similarity 193 member A increases expression ISO Methamphetamine results in increased expression of FAM193A mRNA CTD PMID:26307267 NCBI chr 4:2,535,375...2,732,573
Ensembl chr 4:2,536,647...2,732,573
JBrowse link
G FAM193B family with sequence similarity 193 member B increases expression ISO Methamphetamine results in increased expression of FAM193B mRNA CTD PMID:26307267 NCBI chr 5:177,519,788...177,554,563
Ensembl chr 5:177,519,789...177,554,563
JBrowse link
G FAM71E1 family with sequence similarity 71 member E1 decreases expression ISO Methamphetamine results in decreased expression of FAM71E1 mRNA CTD PMID:19564919 NCBI chr19:50,466,643...50,476,848
Ensembl chr19:50,466,785...50,476,848
JBrowse link
G FANK1 fibronectin type III and ankyrin repeat domains 1 decreases expression ISO Methamphetamine results in decreased expression of FANK1 mRNA CTD PMID:19564919 NCBI chr10:125,896,223...126,009,599
Ensembl chr10:125,896,564...126,009,592
JBrowse link
G FAS Fas cell surface death receptor decreases expression
increases expression
ISO Methamphetamine results in decreased expression of FAS mRNA
Methamphetamine results in increased expression of FAS mRNA
CTD PMID:15644446 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FASLG Fas ligand increases expression ISO Methamphetamine results in increased expression of FASLG mRNA; Methamphetamine results in increased expression of FASLG protein CTD PMID:15644446 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FASTKD3 FAST kinase domains 3 decreases expression ISO Methamphetamine results in decreased expression of FASTKD3 mRNA CTD PMID:26307267 NCBI chr 5:7,859,159...7,869,037
Ensembl chr 5:7,859,159...7,869,037
JBrowse link
G FBLIM1 filamin binding LIM protein 1 increases expression ISO Methamphetamine results in increased expression of FBLIM1 mRNA CTD PMID:19564919 NCBI chr 1:15,756,170...15,786,590
Ensembl chr 1:15,756,607...15,786,594
JBrowse link
G FBXL4 F-box and leucine rich repeat protein 4 decreases expression ISO Methamphetamine results in decreased expression of FBXL4 mRNA CTD PMID:19564919 NCBI chr 6:98,868,535...98,948,006
Ensembl chr 6:98,868,535...98,948,006
JBrowse link
G FBXO28 F-box protein 28 increases expression ISO Methamphetamine results in increased expression of FBXO28 mRNA CTD PMID:19564919 NCBI chr 1:224,114,111...224,162,047
Ensembl chr 1:224,114,111...224,162,047
JBrowse link
G FBXO32 F-box protein 32 increases expression ISO Methamphetamine results in increased expression of FBXO32 mRNA CTD PMID:23933405 NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
JBrowse link
G FBXO33 F-box protein 33 increases expression ISO Methamphetamine results in increased expression of FBXO33 mRNA CTD PMID:19564919 NCBI chr14:39,397,684...39,432,433
Ensembl chr14:39,397,669...39,432,500
JBrowse link
G FCGBP Fc fragment of IgG binding protein decreases expression ISO Methamphetamine results in decreased expression of FCGBP mRNA CTD PMID:26307267 NCBI chr19:39,863,323...39,934,626
Ensembl chr19:39,863,323...39,934,626
JBrowse link
G FGF2 fibroblast growth factor 2 increases expression ISO Methamphetamine results in increased expression of FGF2 mRNA CTD PMID:19564919 NCBI chr 4:122,826,708...122,898,236
Ensembl chr 4:122,826,708...122,898,236
JBrowse link
G FGF4 fibroblast growth factor 4 multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of FGF4 mRNA
Methamphetamine results in increased expression of FGF4 mRNA
CTD PMID:19564919 NCBI chr11:69,771,022...69,775,341
Ensembl chr11:69,771,022...69,775,341
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 increases expression ISO Methamphetamine results in increased expression of FGFR3 mRNA CTD PMID:26307267 NCBI chr 4:1,793,293...1,808,872
Ensembl chr 4:1,793,293...1,808,872
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase affects response to substance EXP FHIT gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459
JBrowse link
G FJX1 four-jointed box kinase 1 decreases expression ISO Methamphetamine results in decreased expression of FJX1 mRNA CTD PMID:19564919 NCBI chr11:35,618,460...35,620,865
Ensembl chr11:35,618,460...35,620,865
JBrowse link
G FKBP15 FKBP prolyl isomerase family member 15 affects response to substance EXP FKBP15 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 9:113,161,006...113,221,325
Ensembl chr 9:113,161,006...113,221,318
JBrowse link
G FKBP4 FKBP prolyl isomerase 4 increases expression ISO Methamphetamine results in increased expression of FKBP4 mRNA CTD PMID:19149911 NCBI chr12:2,794,970...2,805,423
Ensembl chr12:2,794,970...2,805,423
JBrowse link
G FLNA filamin A increases expression ISO Methamphetamine results in increased expression of FLNA mRNA CTD PMID:26307267 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634
JBrowse link
G FLNB filamin B increases expression ISO Methamphetamine results in increased expression of FLNB mRNA CTD PMID:26307267 NCBI chr 3:58,008,422...58,172,251
Ensembl chr 3:58,008,398...58,172,251
JBrowse link
G FLNC filamin C increases expression ISO Methamphetamine results in increased expression of FLNC mRNA CTD PMID:26307267 NCBI chr 7:128,830,406...128,859,272
Ensembl chr 7:128,830,406...128,859,274
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 increases expression ISO Methamphetamine results in increased expression of FLT1 mRNA CTD PMID:26307267 PMID:32035215 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of FMO2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of FMO2 mRNA
CTD PMID:19564919 NCBI chr 1:171,185,208...171,212,686
Ensembl chr 1:171,185,249...171,212,686
JBrowse link
G FMO3 flavin containing dimethylaniline monoxygenase 3 increases metabolic processing EXP FMO3 protein results in increased metabolism of Methamphetamine CTD PMID:27320963 NCBI chr 1:171,090,873...171,117,819
Ensembl chr 1:171,090,901...171,117,819
JBrowse link
G FN1 fibronectin 1 increases expression ISO Methamphetamine results in increased expression of FN1 mRNA CTD PMID:12766323 NCBI chr 2:215,360,862...215,436,167
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
affects response to substance
ISO Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]; FOS protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Idazoxan inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]]; Lidocaine inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]]
Methamphetamine results in increased expression of FOS mRNA; Methamphetamine results in increased expression of FOS protein
[Methamphetamine co-treated with SCH 23390] results in increased expression of FOS mRNA; Carbamazepine inhibits the reaction [Methamphetamine results in increased expression of FOS protein]; Oxytocin inhibits the reaction [Methamphetamine results in increased expression of FOS protein]
Methamphetamine results in increased expression of FOS; Methamphetamine results in increased expression of FOS protein
FOS mRNA affects the susceptibility to Methamphetamine; FOS protein affects the susceptibility to Methamphetamine
CTD PMID:10559418 PMID:10731628 PMID:11754491 PMID:12050851 PMID:19564919 PMID:19689456 PMID:20731630 PMID:20950675 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Methamphetamine results in increased expression of FOSL1 mRNA CTD PMID:19564919 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
JBrowse link
G FOXE1 forkhead box E1 increases expression ISO Methamphetamine results in increased expression of FOXE1 mRNA; Methamphetamine results in increased expression of FOXE1 protein CTD PMID:28341135 NCBI chr 9:97,853,226...97,856,717
Ensembl chr 9:97,853,226...97,856,717
JBrowse link
G FST follistatin decreases expression ISO Methamphetamine results in decreased expression of FST mRNA CTD PMID:28619521 NCBI chr 5:53,480,338...53,487,134
Ensembl chr 5:53,480,626...53,487,134
JBrowse link
G FTCD formimidoyltransferase cyclodeaminase multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of FTCD mRNA
Methamphetamine results in increased expression of FTCD mRNA
CTD PMID:19564919 NCBI chr21:46,135,981...46,156,482
Ensembl chr21:46,136,160...46,155,579
JBrowse link
G FUZ fuzzy planar cell polarity protein increases expression ISO Methamphetamine results in increased expression of FUZ mRNA CTD PMID:26307267 NCBI chr19:49,806,866...49,817,376
Ensembl chr19:49,806,866...49,817,376
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Methamphetamine results in increased expression of FYN mRNA CTD PMID:26307267 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 increases methylation ISO Methamphetamine results in increased methylation of GABARAPL2 promoter CTD PMID:26307267 NCBI chr16:75,566,379...75,577,881
Ensembl chr16:75,566,375...75,577,881
JBrowse link
G GABBR2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions EXP Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] CTD PMID:21729720 NCBI chr 9:98,288,104...98,708,935
Ensembl chr 9:98,288,109...98,708,935
JBrowse link
G GABPA GA binding protein transcription factor subunit alpha increases expression
multiple interactions
ISO Methamphetamine results in increased expression of GABPA mRNA
Lithium inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA]
CTD PMID:19149911 NCBI chr21:25,734,972...25,772,460
Ensembl chr21:25,734,570...25,772,460
JBrowse link
G GABRA1 gamma-aminobutyric acid type A receptor subunit alpha1 multiple interactions EXP Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] CTD PMID:21729720 NCBI chr 5:161,847,191...161,899,971
Ensembl chr 5:161,847,063...161,899,981
JBrowse link
G GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 increases response to substance
multiple interactions
EXP GABRG2 gene results in increased susceptibility to Methamphetamine
Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]
CTD PMID:15772696 PMID:21729720 NCBI chr 5:162,067,465...162,155,539
Ensembl chr 5:162,000,057...162,162,977
JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 increases expression ISO Methamphetamine results in increased expression of GABRG3 mRNA CTD PMID:15644446 NCBI chr15:26,971,181...27,541,984
Ensembl chr15:26,971,181...27,541,984
JBrowse link
G GABRR3 gamma-aminobutyric acid type A receptor subunit rho3 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of GABRR3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GABRR3 mRNA
CTD PMID:19564919 NCBI chr 3:97,985,102...98,035,315
Ensembl chr 3:97,986,673...98,035,304
JBrowse link
G GAD2 glutamate decarboxylase 2 increases expression ISO Methamphetamine results in increased expression of GAD2 mRNA CTD PMID:15601951 NCBI chr10:26,216,372...26,304,558
Ensembl chr10:26,216,665...26,304,558
JBrowse link
G GADD45B growth arrest and DNA damage inducible beta multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45B mRNA
Methamphetamine results in increased expression of GADD45B mRNA
CTD PMID:19564919 NCBI chr19:2,476,127...2,478,259
Ensembl chr19:2,476,122...2,478,259
JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma increases expression
multiple interactions
ISO Methamphetamine results in increased expression of GADD45G mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45G mRNA
CTD PMID:19564919 NCBI chr 9:89,605,009...89,606,555
Ensembl chr 9:89,605,012...89,606,555
JBrowse link
G GAL galanin and GMAP prepropeptide increases expression
decreases expression
EXP
ISO
Methamphetamine results in increased expression of GAL mRNA
Methamphetamine results in decreased expression of GAL mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
JBrowse link
G GALK1 galactokinase 1 decreases expression ISO Methamphetamine results in decreased expression of GALK1 mRNA CTD PMID:19564919 NCBI chr17:75,751,469...75,765,192
Ensembl chr17:75,751,594...75,765,236
JBrowse link
G GALNTL6 polypeptide N-acetylgalactosaminyltransferase like 6 decreases expression ISO Methamphetamine results in decreased expression of GALNTL6 mRNA CTD PMID:26307267 NCBI chr 4:171,812,656...173,041,559
Ensembl chr 4:171,812,254...173,041,559
JBrowse link
G GALT galactose-1-phosphate uridylyltransferase increases expression ISO Methamphetamine results in increased expression of GALT mRNA CTD PMID:26307267 NCBI chr 9:34,646,675...34,651,035
Ensembl chr 9:34,638,133...34,651,035
JBrowse link
G GAP43 growth associated protein 43 multiple interactions
decreases expression
ISO Melatonin inhibits the reaction [Methamphetamine results in decreased expression of GAP43 protein] CTD PMID:19409439 NCBI chr 3:115,623,510...115,721,485
Ensembl chr 3:115,623,510...115,721,490
JBrowse link
G GAS5 growth arrest specific 5 increases expression ISO Methamphetamine results in increased expression of GAS5 mRNA CTD PMID:28619521 NCBI chr 1:173,863,899...173,868,882
Ensembl chr 1:173,858,559...173,868,882
JBrowse link
G GAS8 growth arrest specific 8 multiple interactions
decreases expression
ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of GAS8 mRNA
Methamphetamine results in decreased expression of GAS8 mRNA
CTD PMID:19564919 NCBI chr16:90,019,629...90,044,960
Ensembl chr16:90,019,629...90,044,975
JBrowse link
G GATAD2B GATA zinc finger domain containing 2B increases expression ISO Methamphetamine results in increased expression of GATAD2B mRNA CTD PMID:19564919 NCBI chr 1:153,804,725...153,923,953
Ensembl chr 1:153,789,030...153,923,360
JBrowse link
G GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 increases expression ISO Methamphetamine results in increased expression of GBF1 mRNA CTD PMID:26307267 NCBI chr10:102,230,643...102,382,899
Ensembl chr10:102,245,371...102,382,899
JBrowse link
G GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) increases expression ISO Methamphetamine results in increased expression of GBGT1 mRNA CTD PMID:28341135 NCBI chr 9:133,152,948...133,163,914
Ensembl chr 9:133,152,948...133,163,933
JBrowse link
G GCH1 GTP cyclohydrolase 1 increases expression ISO Methamphetamine results in increased expression of GCH1 mRNA CTD PMID:19564919 NCBI chr14:54,842,016...54,902,826
Ensembl chr14:54,842,008...54,902,826
JBrowse link
G GCSH glycine cleavage system protein H decreases expression ISO Methamphetamine results in decreased expression of GCSH mRNA CTD PMID:19149911 NCBI chr16:81,081,945...81,096,395
Ensembl chr16:81,081,945...81,096,395
JBrowse link
G GDA guanine deaminase decreases expression ISO Methamphetamine results in decreased expression of GDA protein CTD PMID:19826936 NCBI chr 9:72,114,595...72,256,045
Ensembl chr 9:72,114,595...72,257,193
JBrowse link
G GDF15 growth differentiation factor 15 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of GDF15 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr19:18,382,170...18,389,176
Ensembl chr19:18,374,731...18,389,176
JBrowse link
G GDI1 GDP dissociation inhibitor 1 decreases expression ISO Methamphetamine results in decreased expression of GDI1 protein CTD PMID:19826936 NCBI chr  X:154,437,154...154,443,467
Ensembl chr  X:154,436,913...154,443,467
JBrowse link
G GDNF glial cell derived neurotrophic factor decreases response to substance ISO GDNF protein results in decreased susceptibility to Methamphetamine CTD PMID:17356005 NCBI chr 5:37,812,677...37,840,044
Ensembl chr 5:37,812,677...37,840,041
JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle multiple interactions
increases expression
ISO [Methamphetamine co-treated with SCH 23390] affects the expression of GEM mRNA
Methamphetamine results in increased expression of GEM mRNA
CTD PMID:19564919 NCBI chr 8:94,249,249...94,262,345
Ensembl chr 8:94,249,253...94,262,350
JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions
increases expression
affects expression
ISO 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [[PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein]; [PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein; isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; Raclopride inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP mRNA]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; TAAR1 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]
Methamphetamine results in increased expression of GFAP mRNA; Methamphetamine results in increased expression of GFAP protein
Methamphetamine affects the expression of GFAP protein
CTD PMID:9427479 PMID:9634552 PMID:9739098 PMID:10773198 PMID:12766323 PMID:15337264 PMID:15644446 PMID:16088948 PMID:17262233 PMID:19834288 PMID:21867746 PMID:24072398 PMID:26283213 PMID:28919515 PMID:29467000 PMID:32278788 NCBI chr17:44,903,159...44,915,552
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GFRA2 GDNF family receptor alpha 2 increases expression ISO Methamphetamine results in increased expression of GFRA2 mRNA CTD PMID:15644446 NCBI chr 8:21,690,398...21,789,296
Ensembl chr 8:21,690,398...21,812,357
JBrowse link
G GFRA4 GDNF family receptor alpha 4 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of GFRA4 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GFRA4 mRNA
CTD PMID:19564919 NCBI chr20:3,659,248...3,663,399
Ensembl chr20:3,659,248...3,663,399
JBrowse link
G GIGYF1