Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:secondary amine
go back to main search page
Accession:CHEBI:32863 term browser browse the term
Definition:A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups.
Synonyms:exact_synonym: secondary amines
 related_synonym: Formula=HNR2;   R2NH;   SMILES=[H]N([*])[*];   sekundaeres Amin
 alt_id: CHEBI:26618;   CHEBI:9078
 xref: KEGG:C02324
 cyclic_relationship: is_conjugate_base_of CHEBI:137419



show annotations for term's descendants           Sort by:
bisoprolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
ISO ABCB1 protein results in increased transport of Bisoprolol
Bisoprolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; valspodar inhibits the reaction [ABCB1 protein results in increased transport of Bisoprolol]
CTD PMID:16671962 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Adrb1 adrenoceptor beta 1 decreases activity
increases expression
multiple interactions
affects binding
ISO
EXP
Bisoprolol results in decreased activity of ADRB1 protein
Bisoprolol results in increased expression of ADRB1 mRNA
[Bisoprolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; Bisoprolol binds to and results in decreased activity of ADRB1 protein; Bisoprolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Bisoprolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB1 protein]
Bisoprolol binds to ADRB1 protein
CTD PMID:1389726 PMID:2897299 PMID:10372227 PMID:11562432 PMID:12535855 More... NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
increases expression
ISO
EXP
[Bisoprolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Bisoprolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; Bisoprolol binds to and results in decreased activity of ADRB2 protein; Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB2 protein]
Bisoprolol results in increased expression of ADRB2 mRNA
CTD PMID:14730417 PMID:17925438 PMID:20668454 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions ISO Bisoprolol inhibits the reaction [cyanopindolol binds to ADRB3 protein] CTD PMID:14730417 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Bisoprolol results in decreased expression of CCL2 protein CTD PMID:19840533 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Gnas GNAS complex locus increases expression EXP Bisoprolol results in increased expression of GNAS mRNA CTD PMID:20668454 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Il10 interleukin 10 increases expression ISO Bisoprolol results in increased expression of IL10 protein CTD PMID:19840533 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Bisoprolol results in decreased expression of IL1B protein CTD PMID:19840533 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 decreases expression ISO Bisoprolol results in decreased expression of IL6 protein CTD PMID:19840533 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Bisoprolol inhibits the reaction [Terbutaline results in increased expression of INS protein] CTD PMID:12795776 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Prkca protein kinase C, alpha decreases expression EXP Bisoprolol results in decreased expression of PRKCA protein CTD PMID:20668454 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcd protein kinase C, delta decreases expression EXP Bisoprolol results in decreased expression of PRKCD protein CTD PMID:20668454 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Bisoprolol inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Bisoprolol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:19740083 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Bisoprolol results in decreased expression of TNF protein CTD PMID:19840533 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
brimonidine tartrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A multiple interactions ISO
EXP
Brimonidine Tartrate inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]; Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]; Prazosin inhibits the reaction [Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]]; Yohimbine inhibits the reaction [Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]] CTD PMID:8397342 PMID:10742289 PMID:12208771 PMID:12598592 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Agt angiotensinogen multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Brimonidine Tartrate inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation EXP Brimonidine Tartrate results in increased phosphorylation of CREB1 protein CTD PMID:17680988 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Prkca protein kinase C, alpha affects localization
multiple interactions
EXP Brimonidine Tartrate affects the localization of PRKCA protein
Nitric Oxide deficiency promotes the reaction [Brimonidine Tartrate affects the localization of PRKCA protein]
CTD PMID:12388232 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcd protein kinase C, delta affects localization
multiple interactions
EXP Brimonidine Tartrate affects the localization of PRKCD protein
Nitric Oxide deficiency inhibits the reaction [Brimonidine Tartrate affects the localization of PRKCD protein]
CTD PMID:12388232 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Brimonidine Tartrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
diethylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hrh3 histamine receptor H3 multiple interactions EXP
ISO
diethylamine binds to and results in decreased activity of HRH3 protein CTD PMID:17169555 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Ifng interferon gamma multiple interactions ISO [diethylamine co-treated with Sodium Dodecyl Sulfate] results in increased expression of IFNG protein CTD PMID:12062936 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il18 interleukin 18 increases activity ISO diethylamine results in increased activity of IL18 protein CTD PMID:15840424 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases activity ISO diethylamine results in increased activity of IL1A protein CTD PMID:15840424 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [diethylamine co-treated with Sodium Dodecyl Sulfate] results in increased expression of IL4 protein CTD PMID:12062936 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
dimethylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dek DEK proto-oncogene increases secretion ISO DEK protein results in increased secretion of dimethylamine CTD PMID:28558019 NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
JBrowse link
G Hrh3 histamine receptor H3 multiple interactions ISO
EXP
dimethylamine binds to and results in decreased activity of HRH3 protein CTD PMID:17169555 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
dobutamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Dobutamine results in decreased activity of ABCB11 protein CTD PMID:28437613 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Adcy6 adenylate cyclase 6 affects response to substance ISO ADCY6 protein affects the susceptibility to Dobutamine CTD PMID:12393090 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO Dobutamine binds to and results in increased activity of ADRA2A protein CTD PMID:16024912 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Adrb1 adrenoceptor beta 1 affects response to substance
multiple interactions
ISO
EXP
ADRB1 gene affects the susceptibility to Dobutamine; ADRB1 gene polymorphism affects the susceptibility to Dobutamine; ADRB1 protein polymorphism affects the susceptibility to Dobutamine
[Dobutamine co-treated with ICI 118551] results in decreased expression of ADRB1 mRNA; [Dobutamine co-treated with ICI 118551] results in decreased expression of ADRB1 protein; Dobutamine binds to and results in increased activity of ADRB1 protein; Dobutamine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Oxygen deficiency results in increased susceptibility to [Dobutamine binds to and results in increased activity of ADRB1 protein]
ADRB1 gene polymorphism affects the susceptibility to [Dobutamine co-treated with Metoprolol]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Dobutamine binds to and results in increased activity of ADRB1 protein; Dobutamine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of and results in increased uptake of EGFR protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]
CTD PMID:8096834 PMID:10192281 PMID:11753577 PMID:14502278 PMID:15564877 More... NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 affects response to substance ISO ADRB2 gene polymorphism affects the susceptibility to Dobutamine CTD PMID:17094270 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions EXP [Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 mRNA; [Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 protein CTD PMID:19719783 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Ahsg alpha-2-HS-glycoprotein affects response to substance ISO AHSG protein affects the susceptibility to Dobutamine CTD PMID:16177000 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects response to substance
multiple interactions
ISO
EXP
AKT1 protein affects the susceptibility to Dobutamine
Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein]
CTD PMID:16094411 PMID:16339297 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions EXP Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT2 protein] CTD PMID:16339297 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 multiple interactions EXP Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT3 protein] CTD PMID:16339297 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]] CTD PMID:18787115 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]] CTD PMID:18787115 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Dobutamine results in increased expression of BAX protein CTD PMID:15052282 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Dobutamine results in decreased expression of BCL2 protein CTD PMID:15052282 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Dobutamine results in increased expression of BNIP1 protein CTD PMID:15052282 NCBI chr10:16,386,876...16,399,124
Ensembl chr10:16,386,841...16,399,157
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] CTD PMID:12818967 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 protein] CTD PMID:12818968 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Clu clusterin increases expression ISO Dobutamine results in increased expression of CLU protein CTD PMID:15052282 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Comt catechol-O-methyltransferase increases methylation
increases expression
ISO
EXP
COMT protein results in increased methylation of Dobutamine
Dobutamine results in increased expression of COMT mRNA
CTD PMID:11160877 PMID:12423672 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Dobutamine results in increased expression of CPT1A mRNA; Dobutamine results in increased expression of CPT1A protein CTD PMID:8479178 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crem cAMP responsive element modulator affects response to substance ISO CREM protein affects the susceptibility to Dobutamine CTD PMID:12475904 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Ctf1 cardiotrophin 1 affects response to substance ISO CTF1 protein affects the susceptibility to Dobutamine CTD PMID:17150369 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA] CTD PMID:11605937 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Dbh dopamine beta-hydroxylase affects response to substance ISO DBH protein affects the susceptibility to Dobutamine CTD PMID:10338466 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dmd dystrophin increases response to substance ISO DMD gene mutant form results in increased susceptibility to Dobutamine CTD PMID:17440445 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Egfr epidermal growth factor receptor decreases response to substance
multiple interactions
ISO EGFR gene mutant form results in decreased susceptibility to Dobutamine
AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; AG 1879 inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of and results in increased uptake of EGFR protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]
CTD PMID:18599591 PMID:18787115 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Dobutamine binds to and results in increased activity of ESR1 protein CTD PMID:24928891 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO Dobutamine results in increased expression of F3 protein CTD PMID:16286589 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance ISO FGF2 protein affects the susceptibility to Dobutamine CTD PMID:10491406 PMID:14583313 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]; Metoprolol inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity EXP Dobutamine results in increased activity of G6PD protein CTD PMID:1978808 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP GH1 protein promotes the reaction [Dobutamine results in increased metabolism of Lipids] CTD PMID:14981226 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Gk glycerol kinase increases activity EXP Dobutamine results in increased activity of GK protein CTD PMID:12736183 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gnas GNAS complex locus increases response to substance ISO GNAS gene SNP results in increased susceptibility to Dobutamine CTD PMID:19542315 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects response to substance ISO GSK3B gene mutant form affects the susceptibility to Dobutamine CTD PMID:17901358 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]] CTD PMID:18787115 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP esmolol inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]; Metoprolol inhibits the reaction [Dobutamine results in increased expression of HMOX1 mRNA]; Metoprolol inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased expression of HMOX1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]
Dobutamine results in increased expression of HMOX1 mRNA; Dobutamine results in increased expression of HMOX1 protein
CTD PMID:15179140 PMID:16627864 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Igf1 insulin-like growth factor 1 increases response to substance EXP IGF1 protein results in increased susceptibility to Dobutamine CTD PMID:17184500 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]
Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
CTD PMID:11605937 PMID:15502056 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression
EXP
ISO
Dobutamine results in increased expression of IL1B mRNA
Dobutamine results in decreased expression of IL1B mRNA
CTD PMID:9387890 PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression
decreases expression
multiple interactions
ISO
EXP
Dobutamine results in increased expression of IL6 protein
Dobutamine results in decreased expression of IL6 mRNA
Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Dobutamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD PMID:11605937 PMID:12423672 PMID:16286589 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgb1 integrin subunit beta 1 affects response to substance ISO ITGB1 protein affects the susceptibility to Dobutamine CTD PMID:11884376 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]; Metoprolol inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]; Metoprolol inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Dobutamine results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions
affects response to substance
ISO KCNJ11 protein affects the reaction [[Manganese co-treated with Dobutamine] results in increased abundance of Calcium]
KCNJ11 protein affects the susceptibility to Dobutamine
CTD PMID:17189350 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Klk1 kallikrein 1 affects response to substance ISO KLK1 protein affects the susceptibility to Dobutamine CTD PMID:12411458 NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Lep leptin decreases secretion
decreases expression
ISO Dobutamine results in decreased secretion of LEP protein
Dobutamine results in decreased expression of LEP mRNA; Dobutamine results in decreased expression of LEP protein
CTD PMID:9002984 PMID:11022189 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor affects response to substance ISO LEPR protein affects the susceptibility to Dobutamine CTD PMID:20175764 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
[Dobutamine co-treated with ICI 118551] results in increased activity of MAPK1 protein
AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]
Dobutamine results in increased phosphorylation of MAPK1 protein
CTD PMID:16760913 PMID:18787115 PMID:19719783 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
[Dobutamine co-treated with ICI 118551] results in increased activity of MAPK3 protein
AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB1 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; HBEGF protein inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]
Dobutamine results in increased phosphorylation of MAPK3 protein
CTD PMID:16760913 PMID:18787115 PMID:19719783 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP [Dobutamine co-treated with ICI 118551] results in increased activity of MAPK9 protein CTD PMID:19719783 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mb myoglobin affects response to substance ISO MB protein affects the susceptibility to Dobutamine CTD PMID:10468637 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] CTD PMID:15502056 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos1 nitric oxide synthase 1 affects response to substance ISO NOS1 protein affects the susceptibility to Dobutamine CTD PMID:16344403 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 affects response to substance ISO NOS2 protein affects the susceptibility to Dobutamine CTD PMID:9396439 PMID:11489778 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases activity ISO Dobutamine results in increased activity of NR1H4 protein CTD PMID:22414727 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression EXP Dobutamine results in increased expression of PHGDH mRNA CTD PMID:12423672 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Pln phospholamban affects response to substance ISO PLN protein affects the susceptibility to Dobutamine CTD PMID:14991071 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha affects response to substance ISO PPP2CA protein affects the susceptibility to Dobutamine CTD PMID:15247211 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of PRKACA protein] CTD PMID:16339297 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkce protein kinase C, epsilon affects response to substance ISO PRKCE protein affects the susceptibility to Dobutamine CTD PMID:15242976 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prop1 PROP paired-like homeobox 1 decreases response to substance ISO PROP1 gene mutant form results in decreased susceptibility to Dobutamine CTD PMID:19414510 NCBI chr10:35,271,959...35,274,434
Ensembl chr10:35,271,973...35,274,434
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Dobutamine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ren renin multiple interactions
increases expression
increases secretion
increases activity
ISO Cycloheximide inhibits the reaction [Dobutamine results in increased secretion of REN protein]; Dactinomycin inhibits the reaction [Dobutamine results in increased secretion of REN protein]
Dobutamine results in increased expression of REN mRNA
Dobutamine results in increased activity of REN protein
CTD PMID:9203624 PMID:9209250 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G S100a1 S100 calcium binding protein A1 increases response to substance ISO S100A1 gene mutant form results in increased susceptibility to Dobutamine CTD PMID:18645228 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma increases expression EXP Dobutamine results in increased expression of SCNN1G mRNA CTD PMID:16638327 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816
JBrowse link
G Sgcd sarcoglycan, delta affects response to substance ISO SGCD affects the susceptibility to Dobutamine CTD PMID:20675662 NCBI chr10:31,346,480...32,328,364
Ensembl chr10:31,280,511...31,724,840
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases degradation EXP Dobutamine deficiency results in increased degradation of SPTAN1 protein CTD PMID:15849228 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions ISO Dobutamine promotes the reaction [TAC1 protein binds to and results in increased activity of TACR1 protein] CTD PMID:8994422 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions ISO Dobutamine promotes the reaction [TAC1 protein binds to and results in increased activity of TACR1 protein] CTD PMID:8994422 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Dobutamine results in increased expression of TGFB1 mRNA CTD PMID:16760913 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Dobutamine results in increased expression of TGFB2 mRNA CTD PMID:16760913 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tnf tumor necrosis factor decreases expression
decreases secretion
EXP Dobutamine results in decreased expression of TNF mRNA
Dobutamine results in decreased secretion of TNF protein
CTD PMID:12423672 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 decreases expression ISO Dobutamine results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Usf1 upstream transcription factor 1 multiple interactions ISO USF1 gene polymorphism promotes the reaction [Dobutamine results in increased metabolism of Lipids]; USF1 protein affects the reaction [Dobutamine results in increased metabolism of Lipids] CTD PMID:15985485 NCBI chr13:83,845,230...83,854,875
Ensembl chr13:83,822,035...83,854,885
JBrowse link
G Vegfa vascular endothelial growth factor A affects response to substance ISO VEGFA protein affects the susceptibility to Dobutamine CTD PMID:11599061 PMID:14583313 PMID:19237429 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
maleimide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 multiple interactions ISO maleimide analog binds to and results in increased activity of TP53 protein mutant form CTD PMID:15998635 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
methamphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of AANAT mRNA
Lithium inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]
CTD PMID:19149911 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression EXP Methamphetamine results in decreased expression of ABCA1 mRNA CTD PMID:35863504 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
EXP Melatonin inhibits the reaction [Methamphetamine results in decreased expression of ABCB1 protein] CTD PMID:28223141 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression
multiple interactions
ISO
EXP
Methamphetamine results in decreased expression of ABCC6 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCC6 mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 increases expression ISO Methamphetamine results in increased expression of ABCD3 mRNA CTD PMID:26307267 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of ABCD4 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCD4 mRNA
CTD PMID:19564919 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression EXP Methamphetamine results in decreased expression of ABCG1 mRNA CTD PMID:35863504 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCG2 mRNA
Methamphetamine results in decreased expression of ABCG2 mRNA
CTD PMID:19564919 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Methamphetamine results in increased expression of ABL1 mRNA CTD PMID:26307267 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Ablim1 actin-binding LIM protein 1 increases expression ISO
EXP
Methamphetamine results in increased expression of ABLIM1 mRNA CTD PMID:26307267 PMID:32035215 NCBI chr 1:256,083,747...256,372,075
Ensembl chr 1:256,084,297...256,371,969
JBrowse link
G Abo2 histo-blood group ABO system transferase 2 increases expression EXP Methamphetamine results in increased expression of ABO2 mRNA CTD PMID:28341135 NCBI chr 3:10,011,475...10,028,397
Ensembl chr 3:10,002,834...10,028,396
JBrowse link
G Abra actin-binding Rho activating protein multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of ABRA mRNA
Methamphetamine results in increased expression of ABRA mRNA
CTD PMID:19564919 NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255
JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression ISO Methamphetamine results in increased expression of ACACB mRNA CTD PMID:26307267 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 increases expression ISO Methamphetamine results in increased expression of ACIN1 mRNA CTD PMID:26307267 NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001
JBrowse link
G Aco1 aconitase 1 increases expression EXP Methamphetamine results in increased expression of ACO1 protein CTD PMID:19826936 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 increases expression EXP Methamphetamine results in increased expression of ACO2 protein CTD PMID:19826936 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ACOT1 mRNA
Methamphetamine results in decreased expression of ACOT1 mRNA
CTD PMID:19564919 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl increases expression EXP Methamphetamine results in increased expression of ACOX3 mRNA CTD PMID:15644446 NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205
JBrowse link
G Acrbp acrosin binding protein increases expression ISO Methamphetamine results in increased expression of ACRBP mRNA CTD PMID:26307267 NCBI chr 4:157,851,149...157,864,211
Ensembl chr 4:157,841,841...157,864,213
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of ACSL5 mRNA
Lithium inhibits the reaction [Methamphetamine results in increased expression of ACSL5 mRNA]
CTD PMID:19149911 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 affects response to substance ISO ACSL6 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression EXP Methamphetamine results in increased expression of ACTA2 protein CTD PMID:35863504 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actb actin, beta decreases expression EXP Methamphetamine results in decreased expression of ACTB protein CTD PMID:19826936 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression ISO Methamphetamine results in decreased expression of ACTC1 mRNA CTD PMID:25290377 NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523
JBrowse link
G Actg1 actin, gamma 1 decreases expression EXP Methamphetamine results in decreased expression of ACTG1 protein CTD PMID:19826936 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232
JBrowse link
G Acvrl1 activin A receptor like type 1 decreases methylation ISO Methamphetamine results in decreased methylation of ACVRL1 promoter CTD PMID:26307267 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 increases expression ISO Methamphetamine results in increased expression of ADAM15 mRNA CTD PMID:26307267 NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 multiple interactions
increases expression
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in increased expression of ADAMTS9 mRNA
Methamphetamine results in increased expression of ADAMTS9 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
JBrowse link
G Adamtsl5 ADAMTS-like 5 increases expression ISO Methamphetamine results in increased expression of ADAMTSL5 mRNA CTD PMID:26307267 NCBI chr 7:9,362,623...9,371,248
Ensembl chr 7:9,363,237...9,370,285
JBrowse link
G Adck2 aarF domain containing kinase 2 decreases expression EXP Methamphetamine results in decreased expression of ADCK2 mRNA CTD PMID:19564919 NCBI chr 4:68,348,853...68,362,725
Ensembl chr 4:68,348,864...68,374,608
JBrowse link
G Adck5 aarF domain containing kinase 5 decreases expression EXP Methamphetamine results in decreased expression of ADCK5 mRNA CTD PMID:19564919 NCBI chr 7:108,301,623...108,319,439
Ensembl chr 7:108,301,415...108,319,436
JBrowse link
G Adcy3 adenylate cyclase 3 multiple interactions
decreases expression
ISO (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of ADCY3 mRNA] CTD PMID:11756511 NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686
JBrowse link
G Adcy4 adenylate cyclase 4 increases expression ISO Methamphetamine results in increased expression of ADCY4 mRNA CTD PMID:26307267 NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108
JBrowse link
G Adcy6 adenylate cyclase 6 increases expression ISO Methamphetamine results in increased expression of ADCY6 mRNA CTD PMID:26307267 PMID:36914120 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Add2 adducin 2 increases expression EXP Methamphetamine results in increased expression of ADD2 mRNA CTD PMID:19564919 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 increases expression ISO Methamphetamine results in increased expression of ADGRF5 mRNA CTD PMID:26307267 NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression ISO Methamphetamine results in decreased expression of ADH1 mRNA CTD PMID:36914120 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO Methamphetamine results in decreased expression of ADIPOQ mRNA CTD PMID:26307267 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO
EXP
[8-cyclopentyl-1,3-dimethylxanthine binds to and results in decreased activity of ADORA1 protein] inhibits the reaction [[Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine]; [Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine
[N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] promotes the reaction [Methamphetamine results in increased secretion of Dopamine]; [N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] which results in increased susceptibility to Methamphetamine
CTD PMID:7996441 PMID:11043458 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2a adenosine A2a receptor increases response to substance ISO ADORA2A gene SNP results in increased susceptibility to Methamphetamine CTD PMID:20799992 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adora3 adenosine A3 receptor decreases expression
affects response to substance
EXP
ISO
Methamphetamine results in decreased expression of ADORA3 mRNA
ADORA3 affects the susceptibility to Methamphetamine
CTD PMID:19564919 PMID:21867746 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
JBrowse link
G Adpgk ADP-dependent glucokinase decreases expression EXP Methamphetamine results in decreased expression of ADPGK mRNA CTD PMID:19564919 NCBI chr 8:59,699,400...59,727,352
Ensembl chr 8:59,699,388...59,727,351
JBrowse link
G Adra1b adrenoceptor alpha 1B affects response to substance ISO ADRA1B protein affects the susceptibility to Methamphetamine CTD PMID:12871582 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Agbl5 AGBL carboxypeptidase 5 increases expression ISO Methamphetamine results in increased expression of AGBL5 mRNA CTD PMID:26307267 NCBI chr 6:25,472,333...25,492,173
Ensembl chr 6:25,472,333...25,490,738
JBrowse link
G Agmat agmatinase decreases expression EXP Methamphetamine results in decreased expression of AGMAT mRNA CTD PMID:19564919 NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276
JBrowse link
G Agrn agrin increases expression ISO Methamphetamine results in increased expression of AGRN mRNA CTD PMID:26307267 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
JBrowse link
G Agt angiotensinogen increases expression
multiple interactions
EXP Methamphetamine results in increased expression of AGT protein
candesartan cilexetil promotes the reaction [Methamphetamine results in increased expression of AGT protein]
CTD PMID:33421459 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression EXP Methamphetamine results in increased expression of AGTR1A protein CTD PMID:33421459 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahnak AHNAK nucleoprotein increases expression ISO Methamphetamine results in increased expression of AHNAK mRNA CTD PMID:26307267 NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
JBrowse link
G Ahsa2 activator of HSP90 ATPase homolog 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of AHSA2 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of AHSA2 mRNA] CTD PMID:19564919 NCBI chr14:97,476,304...97,485,725
Ensembl chr14:97,476,817...97,485,657
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of AIF1 protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; Minocycline inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]
CTD PMID:26283213 PMID:29467000 PMID:32278788 PMID:32916201 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Ajap1 adherens junctions associated protein 1 increases expression ISO Methamphetamine results in increased expression of AJAP1 mRNA CTD PMID:25290377 NCBI chr 5:163,907,846...164,021,004
Ensembl chr 5:163,907,847...164,020,317
JBrowse link
G Ak1 adenylate kinase 1 decreases expression EXP Methamphetamine results in decreased expression of AK1 protein CTD PMID:19826936 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041
JBrowse link
G Ak5 adenylate kinase 5 affects response to substance ISO AK5 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458
JBrowse link
G Akap13 A-kinase anchoring protein 13 increases expression ISO Methamphetamine results in increased expression of AKAP13 mRNA CTD PMID:26307267 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akap8l A-kinase anchoring protein 8 like increases expression ISO Methamphetamine results in increased expression of AKAP8L mRNA CTD PMID:26307267 NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 decreases methylation ISO Methamphetamine results in decreased methylation of AKR7A5 promoter CTD PMID:26307267 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases response to substance
increases phosphorylation
increases cleavage
decreases phosphorylation
multiple interactions
affects phosphorylation
ISO
EXP
AKT1 gene SNP results in increased susceptibility to Methamphetamine
Methamphetamine results in increased phosphorylation of AKT1 protein
Methamphetamine results in increased cleavage of AKT1 protein
Methamphetamine results in decreased phosphorylation of AKT1 protein
DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein]; Luteolin inhibits the reaction [Methamphetamine results in increased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein
[Rosiglitazone co-treated with Methamphetamine] results in increased phosphorylation of AKT1 protein
Methamphetamine affects the phosphorylation of AKT1 protein
rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein]
CTD PMID:15982448 PMID:26887589 PMID:29981415 PMID:30742852 PMID:31270305 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression ISO Methamphetamine results in decreased expression of ALDH1A1 mRNA CTD PMID:36914120 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 increases expression ISO Methamphetamine results in increased expression of ALDH1A2 mRNA CTD PMID:25290377 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression EXP Methamphetamine results in decreased expression of ALDH2 mRNA CTD PMID:15644446 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions
increases expression
affects localization
EXP 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the localization of ALDOC mRNA]
Methamphetamine results in increased expression of ALDOC protein
CTD PMID:18299792 PMID:19826936 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Alg1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ALG1 mRNA
Methamphetamine results in decreased expression of ALG1 mRNA
CTD PMID:19564919 NCBI chr10:10,346,538...10,356,768
Ensembl chr10:10,346,536...10,356,750
JBrowse link
G Als2cl ALS2 C-terminal like increases expression ISO Methamphetamine results in increased expression of ALS2CL mRNA CTD PMID:26307267 NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419
JBrowse link
G Amdhd2 amidohydrolase domain containing 2 decreases expression EXP Methamphetamine results in decreased expression of AMDHD2 mRNA CTD PMID:19564919 NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095
JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 increases expression EXP Methamphetamine results in increased expression of AMPD1 mRNA CTD PMID:19564919 NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 decreases expression EXP Methamphetamine results in decreased expression of AMPD3 mRNA CTD PMID:15644446 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
JBrowse link
G Angel1 angel homolog 1 decreases expression EXP Methamphetamine results in decreased expression of ANGEL1 mRNA CTD PMID:19564919 NCBI chr 6:106,349,125...106,386,202
Ensembl chr 6:106,349,126...106,386,209
JBrowse link
G Angpt2 angiopoietin 2 increases expression ISO Methamphetamine results in increased expression of ANGPT2 mRNA CTD PMID:25290377 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO Methamphetamine results in decreased expression of ANGPTL2 mRNA CTD PMID:36914120 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
JBrowse link
G Ankrd1 ankyrin repeat domain 1 decreases expression ISO Methamphetamine results in decreased expression of ANKRD1 mRNA CTD PMID:36914120 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Ankrd11 ankyrin repeat domain containing 11 increases expression ISO Methamphetamine results in increased expression of ANKRD11 mRNA CTD PMID:26307267 NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962
JBrowse link
G Ankrd16 ankyrin repeat domain 16 decreases expression EXP Methamphetamine results in decreased expression of ANKRD16 mRNA CTD PMID:19564919 NCBI chr17:66,735,325...66,748,533
Ensembl chr17:66,737,261...66,748,533
JBrowse link
G Ankrd44 ankyrin repeat domain 44 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of ANKRD44 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ANKRD44 mRNA
CTD PMID:19564919 NCBI chr 9:56,126,746...56,427,661
Ensembl chr 9:56,126,747...56,427,508
JBrowse link
G Ankrd9 ankyrin repeat domain 9 increases expression ISO Methamphetamine results in increased expression of ANKRD9 mRNA CTD PMID:36914120 NCBI chr 6:130,001,914...130,008,792
Ensembl chr 6:129,998,486...130,008,923
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO Methamphetamine results in decreased expression of ANKS1B mRNA CTD PMID:26307267 NCBI chr 7:24,313,339...25,479,307
Ensembl chr 7:24,312,843...25,477,693
JBrowse link
G Ano3 anoctamin 3 decreases expression EXP Methamphetamine results in decreased expression of ANO3 mRNA CTD PMID:32035215 NCBI chr 3:97,235,671...97,550,090
Ensembl chr 3:97,238,354...97,550,154
JBrowse link
G Ano6 anoctamin 6 increases expression ISO Methamphetamine results in increased expression of ANO6 mRNA CTD PMID:26307267 NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Anxa3 annexin A3 decreases expression EXP Methamphetamine results in decreased expression of ANXA3 protein CTD PMID:19826936 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Aoah acyloxyacyl hydrolase affects response to substance ISO AOAH gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr17:43,808,110...44,049,458
Ensembl chr17:43,809,638...44,049,148
JBrowse link
G Ap1b1 adaptor related protein complex 1 subunit beta 1 increases expression ISO Methamphetamine results in increased expression of AP1B1 mRNA CTD PMID:26307267 NCBI chr14:79,879,482...79,930,778
Ensembl chr14:79,879,533...79,930,778
JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 increases expression EXP Methamphetamine results in increased expression of APEX2 mRNA CTD PMID:19149911 NCBI chr  X:19,425,684...19,508,459
Ensembl chr  X:19,487,419...19,508,439
JBrowse link
G Aplnr apelin receptor decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of APLNR mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of APLNR mRNA
CTD PMID:19564919 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP Methamphetamine results in decreased expression of APOA2 mRNA CTD PMID:32035215 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apod apolipoprotein D decreases expression EXP Methamphetamine results in decreased expression of APOD mRNA CTD PMID:28619521 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G Apold1 apolipoprotein L domain containing 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of APOLD1 mRNA
Methamphetamine results in increased expression of APOLD1 mRNA
CTD PMID:19564919 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression
increases secretion
EXP
ISO
Methamphetamine results in increased expression of and results in increased cleavage of APP protein
Methamphetamine results in increased expression of APP protein
Rosiglitazone inhibits the reaction [Methamphetamine results in increased expression of APP protein]
Methamphetamine results in increased secretion of APP protein
CTD PMID:30367931 PMID:31270305 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 increases expression ISO Methamphetamine results in increased expression of APPL2 mRNA CTD PMID:26307267 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754
JBrowse link
G Ar androgen receptor increases expression EXP Methamphetamine results in increased expression of AR mRNA CTD PMID:15644446 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 increases expression ISO Methamphetamine results in increased expression of ARAP3 mRNA CTD PMID:26307267 NCBI chr18:29,806,214...29,834,217
Ensembl chr18:29,807,536...29,833,555
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein multiple interactions
increases expression
EXP CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA] CTD PMID:11085305 PMID:19564919 PMID:20298714 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Areg amphiregulin decreases expression ISO Methamphetamine results in decreased expression of AREG mRNA CTD PMID:26307267 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg2 arginase 2 multiple interactions
increases expression
EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] CTD PMID:19149911 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 increases expression ISO Methamphetamine results in increased expression of ARHGAP29 mRNA CTD PMID:26307267 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 increases methylation ISO Methamphetamine results in increased methylation of ARHGAP9 promoter CTD PMID:26307267 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression EXP Methamphetamine results in increased expression of ARHGDIA protein CTD PMID:19826936 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor 1 increases expression ISO Methamphetamine results in increased expression of ARHGEF1 mRNA CTD PMID:26307267 NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 increases expression ISO Methamphetamine results in increased expression of ARHGEF10 mRNA CTD PMID:26307267 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173
JBrowse link
G Arhgef15 Rho guanine nucleotide exchange factor 15 increases expression ISO Methamphetamine results in increased expression of ARHGEF15 mRNA CTD PMID:26307267 NCBI chr10:53,650,521...53,663,269
Ensembl chr10:53,650,553...53,663,913
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO Methamphetamine results in increased expression of ARHGEF2 mRNA CTD PMID:26307267 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Arhgef25 Rho guanine nucleotide exchange factor 25 increases methylation ISO Methamphetamine results in increased methylation of ARHGEF25 promoter CTD PMID:26307267 NCBI chr 7:63,005,938...63,013,325
Ensembl chr 7:63,005,940...63,013,719
JBrowse link
G Arid1a AT-rich interaction domain 1A increases methylation
increases expression
ISO Methamphetamine results in increased methylation of ARID1A promoter
Methamphetamine results in increased expression of ARID1A mRNA
CTD PMID:26307267 NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 increases expression EXP Methamphetamine results in increased expression of ARIH1 mRNA CTD PMID:19564919 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245
JBrowse link
G Arl14ep ADP-ribosylation factor like GTPase 14 effector protein decreases expression EXP Methamphetamine results in decreased expression of ARL14EP mRNA CTD PMID:19564919 NCBI chr 3:93,441,952...93,454,282
Ensembl chr 3:93,443,183...93,454,155
JBrowse link
G Arl5b ADP-ribosylation factor like GTPase 5B multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of ARL5B mRNA
Methamphetamine results in increased expression of ARL5B mRNA
CTD PMID:19564919 NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 increases expression EXP Methamphetamine results in increased expression of ARNT2 mRNA CTD PMID:15644446 NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
JBrowse link
G Arrb2 arrestin, beta 2 increases response to substance ISO ARRB2 gene SNP results in increased susceptibility to Methamphetamine CTD PMID:17233643 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Arrdc2 arrestin domain containing 2 increases expression ISO Methamphetamine results in increased expression of ARRDC2 mRNA CTD PMID:26307267 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029
JBrowse link
G Asb14 ankyrin repeat and SOCS box-containing 14 increases expression ISO Methamphetamine results in increased expression of ASB14 mRNA CTD PMID:26307267 NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135
JBrowse link
G Asic3 acid sensing ion channel subunit 3 increases expression EXP Methamphetamine results in increased expression of ASIC3 mRNA CTD PMID:15644446 NCBI chr 4:10,760,509...10,764,987
Ensembl chr 4:10,760,597...10,764,643
JBrowse link
G Asl argininosuccinate lyase decreases expression EXP Methamphetamine results in decreased expression of ASL mRNA CTD PMID:19564919 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression ISO Methamphetamine results in decreased expression of ASPM mRNA CTD PMID:25290377 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
JBrowse link
G Astn2 astrotactin 2 affects response to substance ISO ASTN2 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 5:78,758,142...79,744,021
Ensembl chr 5:78,758,142...79,748,273
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of ATF3 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF3 mRNA]
Methamphetamine results in increased expression of ATF3 mRNA; Methamphetamine results in increased expression of ATF3 protein
CTD PMID:19564919 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
EXP
ISO
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 protein]
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein]
Methamphetamine results in increased expression of ATF4 mRNA; Methamphetamine results in increased expression of ATF4 protein
CTD PMID:19564919 PMID:27323860 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 increases expression
increases cleavage
affects localization
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of ATF6 mRNA; Methamphetamine results in increased expression of ATF6 protein
Methamphetamine results in increased cleavage of ATF6 protein
Methamphetamine affects the localization of ATF6 protein
ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 protein]; Methamphetamine results in decreased expression of and results in increased cleavage of ATF6 protein; Naltrexone inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein]
Melatonin inhibits the reaction [Methamphetamine results in increased expression of ATF6 protein]
CTD PMID:19564919 PMID:27323860 PMID:28070110 PMID:34214594 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atf6b activating transcription factor 6 beta increases expression
multiple interactions
EXP Methamphetamine results in increased expression of ATF6B protein
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of ATF6B protein]
CTD PMID:34214594 NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894
JBrowse link
G Atg14 autophagy related 14 increases expression EXP Methamphetamine results in increased expression of ATG14 mRNA CTD PMID:32676729 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
JBrowse link
G Atg16l1 autophagy related 16-like 1 increases expression EXP Methamphetamine results in increased expression of ATG16L1 mRNA CTD PMID:32676729 NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
JBrowse link
G Atg2a autophagy related 2A increases expression EXP Methamphetamine results in increased expression of ATG2A mRNA CTD PMID:32676729 NCBI chr 1:203,542,559...203,562,242
Ensembl chr 1:203,542,559...203,562,242
JBrowse link
G Atg5 autophagy related 5 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of ATG5 mRNA; Methamphetamine results in increased expression of ATG5 protein
Luteolin inhibits the reaction [Methamphetamine results in increased expression of ATG5 protein]
CTD PMID:32035215 PMID:32676729 PMID:33359793 PMID:34374793 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression EXP Methamphetamine results in decreased expression of ATP1A1 mRNA CTD PMID:19149911 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 increases expression EXP Methamphetamine results in increased expression of ATP2A1 mRNA CTD PMID:34374793 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
decreases expression
EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of ATP2A2 mRNA] CTD PMID:19149911 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression EXP Methamphetamine results in decreased expression of ATP5F1B protein CTD PMID:19826936 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d decreases expression EXP Methamphetamine results in decreased expression of ATP5PD protein CTD PMID:17904249 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression ISO Methamphetamine results in increased expression of ATP6V0A1 mRNA CTD PMID:26307267 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 increases expression EXP Methamphetamine results in increased expression of ATP6V0E2 mRNA CTD PMID:32035215 NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression EXP
ISO
Methamphetamine results in decreased expression of ATP6V1B2 protein CTD PMID:16181420 PMID:19826936 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 decreases expression EXP Methamphetamine results in decreased expression of ATP6V1C2 mRNA CTD PMID:19564919 NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
JBrowse link
G Atxn2 ataxin 2 increases expression ISO Methamphetamine results in increased expression of ATXN2 mRNA CTD PMID:36914120 NCBI chr12:34,754,132...34,851,175
Ensembl chr12:34,754,137...34,851,479
JBrowse link
G Atxn2l ataxin 2-like increases expression ISO Methamphetamine results in increased expression of ATXN2L mRNA CTD PMID:26307267 NCBI chr 1:181,078,293...181,090,079
Ensembl chr 1:181,078,288...181,089,686
JBrowse link
G Atxn7l1 ataxin 7-like 1 increases expression ISO Methamphetamine results in increased expression of ATXN7L1 mRNA CTD PMID:26307267 NCBI chr 6:49,759,876...49,982,323
Ensembl chr 6:49,759,883...49,982,320
JBrowse link
G Aurkc aurora kinase C decreases expression EXP Methamphetamine results in decreased expression of AURKC mRNA CTD PMID:19564919 NCBI chr 1:66,843,653...66,849,775
Ensembl chr 1:66,843,653...66,864,386
JBrowse link
G Avp arginine vasopressin affects expression
multiple interactions
EXP Methamphetamine affects the expression of AVP mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of AVP mRNA
CTD PMID:19564919 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G B3galt4 Beta-1,3-galactosyltransferase 4 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of B3GALT4 mRNA
Methamphetamine results in decreased expression of B3GALT4 mRNA
CTD PMID:19564919 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315
JBrowse link
G Bace1 beta-secretase 1 increases expression EXP Methamphetamine results in increased expression of BACE1 protein CTD PMID:30367931 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bach2 BTB domain and CNC homolog 2 decreases expression ISO Methamphetamine results in decreased expression of BACH2 mRNA CTD PMID:26307267 NCBI chr 5:46,632,338...46,982,676
Ensembl chr 5:46,638,317...46,977,877
JBrowse link
G Baiap3 BAI1-associated protein 3 increases expression ISO Methamphetamine results in increased expression of BAIAP3 mRNA CTD PMID:25290377 NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
ISO [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAK1 protein
Methamphetamine results in increased expression of BAK1 protein
CTD PMID:23820845 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Banp Btg3 associated nuclear protein increases expression ISO Methamphetamine results in increased expression of BANP mRNA CTD PMID:26307267 NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738
JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression EXP Methamphetamine results in decreased expression of BARD1 mRNA CTD PMID:28341135 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein]
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of BAX protein]
Methamphetamine results in increased expression of BAX mRNA; Methamphetamine results in increased expression of BAX protein
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX protein; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of BAX protein]
CTD PMID:19149911 PMID:23820845 PMID:26307267 PMID:26524635 PMID:26923100 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B increases expression ISO Methamphetamine results in increased expression of BAZ1B mRNA CTD PMID:26307267 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
JBrowse link
G Baz2a bromodomain adjacent to zinc finger domain, 2A increases expression ISO Methamphetamine results in increased expression of BAZ2A mRNA CTD PMID:26307267 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression
ISO
EXP
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]
Methamphetamine results in increased expression of BBC3 protein
BBC3 protein promotes the reaction [Methamphetamine results in increased expression of NOS2 protein]
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BBC3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BBC3 protein]
Methamphetamine results in increased expression of BBC3 mRNA; Methamphetamine results in increased expression of BBC3 protein
CTD PMID:23820845 PMID:26524635 PMID:30394308 PMID:34214594 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects response to substance
increases expression
decreases expression
multiple interactions
ISO
EXP
BCL2 protein affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of BCL2 protein
Methamphetamine results in decreased expression of BCL2 protein
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2 mRNA; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]
Methamphetamine results in decreased expression of BCL2 mRNA; Methamphetamine results in decreased expression of BCL2 protein
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SOD1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; bafilomycin A1 promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; GxTX-1E, Plesiophrictus guangxiensis inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Olanzapine inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; STX17 protein inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]
CTD PMID:11457507 PMID:12050851 PMID:15276877 PMID:19149911 PMID:23820845 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 affects expression
decreases expression
multiple interactions
increases methylation
increases expression
EXP
ISO
Methamphetamine affects the expression of BCL2L1 mRNA alternative form
Methamphetamine results in decreased expression of BCL2L1 protein
EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]
Methamphetamine results in increased methylation of BCL2L1 promoter
Methamphetamine results in increased expression of BCL2L1 mRNA
Methamphetamine results in decreased expression of BCL2L1 mRNA
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2L1 mRNA
CTD PMID:10336889 PMID:23820845 PMID:26307267 PMID:31422080 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 Bcl2-like 11 multiple interactions
increases expression
ISO
EXP
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein
Methamphetamine results in increased expression of BCL2L11 protein
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BCL2L11 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BCL2L11 protein]
CTD PMID:23820845 PMID:34214594 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l15 Bcl2-like 15 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL2L15 mRNA
Methamphetamine results in increased expression of BCL2L15 mRNA
CTD PMID:19564919 NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
JBrowse link
G Bcl2l2 Bcl2-like 2 increases expression ISO Methamphetamine results in increased expression of BCL2L2 mRNA CTD PMID:26307267 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL6 mRNA
Methamphetamine results in increased expression of BCL6 mRNA
CTD PMID:19564919 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bcl9l BCL9 like increases expression ISO Methamphetamine results in increased expression of BCL9L mRNA CTD PMID:26307267 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 increases expression ISO Methamphetamine results in increased expression of BDH1 mRNA CTD PMID:36914120 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
JBrowse link
G Bdnf brain-derived neurotrophic factor increases response to substance
increases expression
multiple interactions
decreases expression
affects response to substance
ISO
EXP
BDNF gene SNP results in increased susceptibility to Methamphetamine
Methamphetamine results in increased expression of BDNF protein
Metformin inhibits the reaction [Methamphetamine results in decreased expression of BDNF protein]
BDNF protein affects the susceptibility to Methamphetamine
BDNF gene polymorphism affects the susceptibility to Methamphetamine
CTD PMID:15050682 PMID:16039058 PMID:19462300 PMID:20736000 PMID:27373168 More... NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
increases phosphorylation
EXP
ISO
CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein]
NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; sulforaphane inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein]
Methamphetamine results in increased phosphorylation of BECN1 protein
DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]
CTD PMID:26825372 PMID:31059759 PMID:32035215 PMID:32676729 PMID:33359793 More... NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 affects expression
multiple interactions
EXP Methamphetamine affects the expression of BHMT2 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of BHMT2 mRNA
CTD PMID:19564919 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
JBrowse link
G Bid BH3 interacting domain death agonist increases expression
multiple interactions
ISO Methamphetamine results in increased expression of BID mRNA; Methamphetamine results in increased expression of BID protein modified form
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form
CTD PMID:23820845 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bin1 bridging integrator 1 decreases expression EXP Methamphetamine results in decreased expression of BIN1 protein CTD PMID:19826936 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Methamphetamine results in decreased expression of BIRC5 mRNA CTD PMID:25290377 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression EXP Methamphetamine results in increased expression of BMAL1 mRNA; Methamphetamine results in increased expression of BMAL1 protein CTD PMID:35863504 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Methamphetamine results in increased expression of BNIP3 mRNA CTD PMID:36914120 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase increases expression EXP Methamphetamine results in increased expression of BRAF mRNA CTD PMID:19564919 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Brd2 bromodomain containing 2 increases expression ISO Methamphetamine results in increased expression of BRD2 mRNA CTD PMID:26307267 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
JBrowse link
G Brd9 bromodomain containing 9 increases expression ISO Methamphetamine results in increased expression of BRD9 mRNA CTD PMID:26307267 NCBI chr 1:29,329,981...29,357,285
Ensembl chr 1:29,329,985...29,357,016
JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 increases expression ISO Methamphetamine results in increased expression of BRWD1 mRNA CTD PMID:26307267 NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768
JBrowse link
G Bspry B-box and SPRY domain containing decreases expression EXP Methamphetamine results in decreased expression of BSPRY mRNA CTD PMID:19564919 NCBI chr 5:75,927,397...75,949,585
Ensembl chr 5:75,927,405...75,949,583
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression EXP Methamphetamine results in increased expression of BST2 mRNA CTD PMID:32035215 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Btaf1 B-TFIID TATA-box binding protein associated factor 1 increases expression EXP Methamphetamine results in increased expression of BTAF1 mRNA CTD PMID:19564919 NCBI chr 1:234,653,219...234,743,903
Ensembl chr 1:234,653,156...234,743,903
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Methamphetamine results in increased expression of BTG2 mRNA CTD PMID:19564919 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression EXP Methamphetamine results in decreased expression of BUB1B mRNA CTD PMID:28341135 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G C10h16orf89 similar to human chromosome 16 open reading frame 89 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of C10H16ORF89 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of C10H16ORF89 mRNA
CTD PMID:19564919 NCBI chr10:10,361,909...10,371,046
Ensembl chr10:10,361,948...10,371,046
JBrowse link
G C15h8orf58 similar to human chromosome 8 open reading frame 58 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of C15H8ORF58 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of C15H8ORF58 mRNA
CTD PMID:19564919 NCBI chr15:45,228,615...45,235,274
Ensembl chr15:45,228,615...45,233,254
JBrowse link
G C19h16orf87 similar to human chromosome 16 open reading frame 87 increases expression EXP Methamphetamine results in increased expression of C19H16ORF87 mRNA CTD PMID:19564919 NCBI chr19:21,626,390...21,653,869
Ensembl chr19:21,626,914...21,654,255
JBrowse link
G C1ql1 complement C1q like 1 decreases expression EXP Methamphetamine results in decreased expression of C1QL1 mRNA CTD PMID:19564919 NCBI chr10:87,902,125...87,909,556
Ensembl chr10:87,902,137...87,909,310
JBrowse link
G C1qtnf7 C1q and TNF related 7 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of C1QTNF7 mRNA
Methamphetamine results in decreased expression of C1QTNF7 mRNA
CTD PMID:19564919 NCBI chr14:67,467,888...67,580,477
Ensembl chr14:67,468,014...67,580,410
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 increases expression EXP Methamphetamine results in increased expression of C2CD2 mRNA CTD PMID:19564919 NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
JBrowse link
G C2h3orf33 similar to human chromosome 3 open reading frame 33 decreases expression EXP Methamphetamine results in decreased expression of C2H3ORF33 mRNA CTD PMID:19564919 NCBI chr 2:148,376,598...148,404,343
Ensembl chr 2:148,380,581...148,404,387
JBrowse link
G C3h11orf96 similar to human chromosome 11 open reading frame 96 increases expression EXP Methamphetamine results in increased expression of C3H11ORF96 mRNA CTD PMID:19564919 NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523
JBrowse link
G C4bpb complement component 4 binding protein, beta decreases expression EXP Methamphetamine results in decreased expression of C4BPB mRNA CTD PMID:19564919 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817
JBrowse link
G C5h1orf210 similar to human chromosome 1 open reading frame 210 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of C5H1ORF210 mRNA
Methamphetamine results in decreased expression of C5H1ORF210 mRNA
CTD PMID:19564919 NCBI chr 5:132,048,755...132,051,913
Ensembl chr 5:132,048,773...132,051,925
JBrowse link
G C8g complement C8 gamma chain decreases expression EXP Methamphetamine results in decreased expression of C8G mRNA CTD PMID:19564919 NCBI chr 3:8,320,503...8,322,087
Ensembl chr 3:8,305,920...8,323,495
JBrowse link
G Cab39l calcium binding protein 39-like decreases expression ISO Methamphetamine results in decreased expression of CAB39L mRNA CTD PMID:26307267 NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
JBrowse link
G Cabin1 calcineurin binding protein 1 increases expression ISO Methamphetamine results in increased expression of CABIN1 mRNA CTD PMID:26307267 NCBI chr20:12,893,314...13,015,357
Ensembl chr20:12,893,358...13,015,357
JBrowse link
G Cabyr calcium binding tyrosine phosphorylation regulated increases expression ISO Methamphetamine results in increased expression of CABYR mRNA CTD PMID:26307267 NCBI chr18:3,892,062...3,904,391
Ensembl chr18:3,892,132...3,903,840
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C decreases methylation
increases expression
ISO
EXP
Methamphetamine results in decreased methylation of CACNA1C promoter
Methamphetamine results in increased expression of CACNA1C mRNA
Methamphetamine results in increased expression of CACNA1C mRNA; Methamphetamine results in increased expression of CACNA1C protein
CTD PMID:26307267 PMID:35863504 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects response to substance
increases expression
multiple interactions
ISO CACNA2D1 protein affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of CACNA2D1 mRNA; Methamphetamine results in increased expression of CACNA2D1 protein
[gabapentin binds to and results in decreased activity of CACNA2D1 protein] which results in decreased susceptibility to Methamphetamine; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; gabapentin inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]
CTD PMID:20340177 PMID:21182903 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 increases expression EXP Methamphetamine results in increased expression of CACNB4 mRNA CTD PMID:19564919 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Cacybp calcyclin binding protein increases expression EXP Methamphetamine results in increased expression of CACYBP mRNA CTD PMID:19564919 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
JBrowse link
G Calb2 calbindin 2 decreases expression EXP Methamphetamine results in decreased expression of CALB2 mRNA CTD PMID:28619521 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Calhm2 calcium homeostasis modulator family member 2 increases expression EXP Methamphetamine results in increased expression of CALHM2 mRNA CTD PMID:19564919 NCBI chr 1:246,022,324...246,028,050
Ensembl chr 1:246,022,324...246,028,218
JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression ISO Methamphetamine results in increased expression of CAMTA2 mRNA CTD PMID:26307267 NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta decreases expression ISO Methamphetamine results in decreased expression of CAPZB protein CTD PMID:16181420 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Car1 carbonic anhydrase 1 increases expression EXP Methamphetamine results in increased expression of CAR1 protein CTD PMID:19826936 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car11 carbonic anhydrase 11 decreases expression EXP Methamphetamine results in decreased expression of CAR11 mRNA CTD PMID:32035215 NCBI chr 1:96,169,900...96,175,191
Ensembl chr 1:96,170,080...96,175,191
JBrowse link
G Car4 carbonic anhydrase 4 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CAR4 mRNA
Methamphetamine results in decreased expression of CAR4 mRNA
CTD PMID:19564919 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Car5b carbonic anhydrase 5B increases expression
multiple interactions
EXP Methamphetamine results in increased expression of CAR5B mRNA
Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CAR5B mRNA]
CTD PMID:19149911 NCBI chr  X:30,474,697...30,534,797
Ensembl chr  X:30,474,784...30,533,837
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression EXP Methamphetamine results in decreased expression of CARHSP1 mRNA CTD PMID:19564919 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
JBrowse link
G Carns1 carnosine synthase 1 increases expression ISO Methamphetamine results in increased expression of CARNS1 mRNA CTD PMID:26307267 NCBI chr 1:201,459,061...201,470,019
Ensembl chr 1:201,459,076...201,469,845
JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression
increases cleavage
ISO MIR143 mRNA affects the reaction [Methamphetamine results in increased cleavage of CASP1 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased cleavage of CASP1 protein]
Methamphetamine results in increased expression of CASP1 protein
CTD PMID:30394308 PMID:33359793 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp12 caspase 12 increases cleavage
decreases expression
multiple interactions
increases expression
EXP
ISO
Methamphetamine results in increased cleavage of CASP12 protein
Methamphetamine results in decreased expression of CASP12 protein
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP12 protein]
Methamphetamine results in increased expression of CASP12 mRNA; Methamphetamine results in increased expression of CASP12 protein
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased cleavage of CASP12 protein]
CTD PMID:28070110 PMID:28619521 PMID:29705343 PMID:32203791 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp2 caspase 2 increases expression EXP Methamphetamine results in increased expression of CASP2 mRNA CTD PMID:19564919 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
decreases expression
increases cleavage
decreases cleavage
affects cleavage
increases expression
ISO
EXP
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; [Methamphetamine co-treated with tin protoporphyrin IX] results in increased cleavage of CASP3 protein; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; JUN protein affects the reaction [Methamphetamine results in increased activity of CASP3 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]
Methamphetamine results in decreased expression of CASP3 protein
Methamphetamine results in decreased cleavage of CASP3 protein
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP3 protein; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP3 protein]
Methamphetamine affects the cleavage of CASP3 protein
2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; 3-methyladenine promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; GxTX-1E, Plesiophrictus guangxiensis inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of CASP3 protein]; KN 93 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; Luteolin inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein; Nifedipine inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; W 7 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; wedelolactone inhibits the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]
Methamphetamine results in increased expression of CASP3 mRNA; Methamphetamine results in increased expression of CASP3 protein modified form
CTD PMID:12391261 PMID:19149911 PMID:19442829 PMID:23933405 PMID:25127757 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 multiple interactions
increases expression
EXP CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA]
Methamphetamine results in increased expression of CASP4 mRNA; Methamphetamine results in increased expression of CASP4 protein alternative form
CTD PMID:19149911 PMID:25631491 PMID:28619521 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 increases cleavage EXP Methamphetamine results in increased cleavage of CASP6 protein CTD PMID:32676729 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
ISO
EXP
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP9 protein; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein] CTD PMID:27323860 PMID:32676729 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases expression
increases activity
multiple interactions
decreases activity
ISO
EXP
Methamphetamine results in decreased expression of CAT protein
Methamphetamine results in increased activity of CAT protein
ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of CAT protein]
Methamphetamine results in decreased activity of CAT protein
Taurine inhibits the reaction [Methamphetamine results in decreased activity of CAT protein]
CTD PMID:12797468 PMID:19948197 PMID:23041169 PMID:24430743 PMID:29467000 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 increases expression EXP Methamphetamine results in increased expression of CAV1 mRNA CTD PMID:32035215 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbll1 Cbl proto-oncogene like 1 increases expression EXP Methamphetamine results in increased expression of CBLL1 mRNA CTD PMID:19564919 NCBI chr 6:48,071,190...48,086,174
Ensembl chr 6:48,071,190...48,086,444
JBrowse link
G Cbr1 carbonyl reductase 1 decreases expression EXP Methamphetamine results in decreased expression of CBR1 mRNA CTD PMID:15644446 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Cbx1 chromobox 1 decreases expression ISO Methamphetamine results in decreased expression of CBX1 mRNA CTD PMID:26307267 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
JBrowse link
G Cbx8 chromobox 8 decreases expression EXP Methamphetamine results in decreased expression of CBX8 mRNA CTD PMID:19564919 NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024
JBrowse link
G Cc2d1b coiled-coil and C2 domain containing 1B multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CC2D1B mRNA
Methamphetamine results in decreased expression of CC2D1B mRNA
CTD PMID:19564919 NCBI chr 5:123,353,289...123,367,343
Ensembl chr 5:123,353,292...123,367,318
JBrowse link
G Ccdc116 coiled-coil domain containing 116 increases expression EXP Methamphetamine results in increased expression of CCDC116 mRNA CTD PMID:19564919 NCBI chr11:83,842,707...83,850,607
Ensembl chr11:83,845,557...83,850,607
JBrowse link
G Ccdc117 coiled-coil domain containing 117 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of CCDC117 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CCDC117 mRNA
CTD PMID:19564919 NCBI chr14:80,399,236...80,409,824
Ensembl chr14:80,400,294...80,409,659
JBrowse link
G Ccdc51 coiled-coil domain containing 51 increases methylation ISO Methamphetamine results in increased methylation of CCDC51 promoter CTD PMID:26307267 NCBI chr 8:109,722,595...109,741,478
Ensembl chr 8:109,722,557...109,741,472
JBrowse link
G Ccdc57 coiled-coil domain containing 57 decreases expression EXP Methamphetamine results in decreased expression of CCDC57 mRNA CTD PMID:32035215 NCBI chr10:106,092,784...106,196,405
Ensembl chr10:106,092,947...106,196,077
JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 affects response to substance ISO CCHCR1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr20:3,205,675...3,218,437
Ensembl chr20:3,205,676...3,218,308
JBrowse link
G Cck cholecystokinin multiple interactions EXP
ISO
CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; CCK protein modified form inhibits the reaction [Methamphetamine results in increased phosphorylation of NCF1 protein]
CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]
CTD PMID:27565679 PMID:32916201 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Cckbr cholecystokinin B receptor increases expression ISO Methamphetamine results in increased expression of CCKBR mRNA CTD PMID:32916201 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases expression EXP Methamphetamine results in increased expression of CCL12 mRNA CTD PMID:28341135 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression EXP Methamphetamine results in increased expression of CCL4 mRNA CTD PMID:19564919 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression EXP Methamphetamine results in decreased expression of CCL5 mRNA CTD PMID:19564919 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 increases expression ISO Methamphetamine results in increased expression of CCL6 mRNA CTD PMID:36914120 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CCN1 mRNA
Methamphetamine results in increased expression of CCN1 mRNA
CTD PMID:19564919 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccna1 cyclin A1 multiple interactions
decreases expression
EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCNA1 mRNA] CTD PMID:19149911 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP Methamphetamine results in decreased expression of CCNA2 mRNA; Methamphetamine results in decreased expression of CCNA2 protein CTD PMID:28341135 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression EXP Methamphetamine results in decreased expression of CCNB1 mRNA; Methamphetamine results in decreased expression of CCNB1 protein CTD PMID:28341135 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO
EXP
Methamphetamine results in decreased expression of CCNB2 mRNA
Methamphetamine results in decreased expression of CCNB2 mRNA; Methamphetamine results in decreased expression of CCNB2 protein
CTD PMID:25290377 PMID:28341135 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of CCND1 mRNA
Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCND1 mRNA]
CTD PMID:19149911 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 decreases expression EXP Methamphetamine results in decreased expression of CCNE1 protein CTD PMID:28341135 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Methamphetamine results in increased expression of CCNL1 mRNA CTD PMID:19564919 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368
JBrowse link
G Ccnl2 cyclin L2 increases expression ISO Methamphetamine results in increased expression of CCNL2 mRNA CTD PMID:26307267 NCBI chr 5:166,416,940...166,428,997
Ensembl chr 5:166,417,508...166,436,882
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases response to substance
increases expression
increases methylation
ISO CCR2 protein results in increased susceptibility to Methamphetamine
Methamphetamine results in increased expression of CCR2 mRNA
Methamphetamine results in increased methylation of CCR2 promoter
CTD PMID:20624155 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of CCR5 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CCR5 mRNA
CTD PMID:19564919 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 decreases expression ISO Methamphetamine results in decreased expression of CCR7 mRNA CTD PMID:26307267 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 decreases expression EXP Methamphetamine results in decreased expression of CCT2 protein CTD PMID:19826936 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression EXP Methamphetamine results in decreased expression of CCT5 protein CTD PMID:19826936 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd151 CD151 molecule (Raph blood group) increases expression EXP Methamphetamine results in increased expression of CD151 mRNA CTD PMID:32035215 NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753
JBrowse link
G Cd177 CD177 molecule increases expression ISO Methamphetamine results in increased expression of CD177 mRNA CTD PMID:25290377 NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621
JBrowse link
G Cd36 CD36 molecule increases expression ISO Methamphetamine results in increased expression of CD36 mRNA; Methamphetamine results in increased expression of CD36 protein CTD PMID:35643125 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd3d CD3 delta subunit of T-cell receptor complex multiple interactions
increases expression
ISO
EXP
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein] CTD PMID:29705343 NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) affects response to substance ISO CD55 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression EXP Methamphetamine results in increased expression of CDC42EP3 mRNA CTD PMID:19564919 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Methamphetamine results in decreased expression of CDC45 mRNA CTD PMID:25290377 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression EXP Methamphetamine results in decreased expression of CDCA3 mRNA; Methamphetamine results in decreased expression of CDCA3 protein CTD PMID:28341135 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO Methamphetamine results in decreased expression of CDCA7 mRNA CTD PMID:26307267 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO Methamphetamine results in decreased expression of CDCA8 mRNA CTD PMID:25290377 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
JBrowse link
G Cdh13 cadherin 13 affects response to substance ISO CDH13 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cdh5 cadherin 5 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of CDH5 mRNA
Luteolin inhibits the reaction [Methamphetamine results in increased expression of CDH5 mRNA]
CTD PMID:32035215 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
JBrowse link
G Cdhr2 cadherin-related family member 2 decreases expression EXP Methamphetamine results in decreased expression of CDHR2 mRNA CTD PMID:19564919 NCBI chr17:9,876,853...9,913,356
Ensembl chr17:9,876,860...9,912,575
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
decreases expression
EXP Methamphetamine results in increased expression of CDK1 mRNA
Methamphetamine results in decreased expression of CDK1 mRNA; Methamphetamine results in decreased expression of CDK1 protein
CTD PMID:15644446 PMID:28341135 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk10 cyclin-dependent kinase 10 decreases expression EXP Methamphetamine results in decreased expression of CDK10 mRNA CTD PMID:19564919 NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078
JBrowse link
G Cdk5 cyclin-dependent kinase 5 multiple interactions
increases expression
EXP
ISO
CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]
methamphetamine increases expression of Cdk5 protein in the ventral tegmental area and nucleus accumbens
Methamphetamine results in increased expression of CDK5 protein
SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of CDK5 protein]
CTD
RGD
PMID:29705343 PMID:32278788 PMID:28782589 RGD:401900303 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression EXP Methamphetamine results in increased expression of CDK6 mRNA CTD PMID:19564919 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdk9 cyclin-dependent kinase 9 increases expression ISO Methamphetamine results in increased expression of CDK9 mRNA CTD PMID:26307267 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in increased expression of CDKN1A mRNA; GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN1A protein]
Methamphetamine results in increased expression of CDKN1A mRNA; Methamphetamine results in increased expression of CDKN1A protein
CTD PMID:19564919 PMID:36914120 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
increases expression
EXP
ISO
GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN2A protein] CTD PMID:36914120 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression EXP Methamphetamine results in increased expression of CDKN2B mRNA CTD PMID:15644446 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdpf1 cysteine rich, DPF motif domain containing 1 decreases expression EXP Methamphetamine results in decreased expression of CDPF1 mRNA CTD PMID:19564919 NCBI chr 7:116,896,672...116,905,438
Ensembl chr 7:116,901,003...116,905,406
JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 increases expression EXP Methamphetamine results in increased expression of CDR2 mRNA CTD PMID:19564919 NCBI chr 1:175,502,837...175,527,746
Ensembl chr 1:175,502,838...175,537,472
JBrowse link
G Cds2 CDP-diacylglycerol synthase 2 increases expression ISO Methamphetamine results in increased expression of CDS2 mRNA CTD PMID:26307267 NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of CEBPB mRNA; Methamphetamine results in increased expression of CEBPB protein
CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]
[Methamphetamine co-treated with SCH 23390] results in increased expression of CEBPB mRNA; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein]
CTD PMID:19564919 PMID:31059759 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cela1 chymotrypsin like elastase 1 decreases expression ISO Methamphetamine results in decreased expression of CELA1 mRNA CTD PMID:26307267 NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285
JBrowse link
G Cenph centromere protein H decreases expression EXP Methamphetamine results in decreased expression of CENPH mRNA CTD PMID:28341135 NCBI chr 2:31,896,675...31,910,179
Ensembl chr 2:31,894,667...31,910,154
JBrowse link
G Cenpq centromere protein Q decreases expression EXP Methamphetamine results in decreased expression of CENPQ mRNA CTD PMID:28341135 NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:19,957,048...19,972,789
JBrowse link
G Cenpw centromere protein W decreases expression EXP Methamphetamine results in decreased expression of CENPW mRNA CTD PMID:28341135 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464
JBrowse link
G Cep104 centrosomal protein 104 multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CEP104 mRNA
Methamphetamine affects the expression of CEP104 mRNA
CTD PMID:19564919 NCBI chr 5:164,534,773...164,567,260
Ensembl chr 5:164,534,782...164,567,248
JBrowse link
G Cep55 centrosomal protein 55 decreases expression ISO Methamphetamine results in decreased expression of CEP55 mRNA CTD PMID:25290377 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
JBrowse link
G Cep72 centrosomal protein 72 decreases expression EXP Methamphetamine results in decreased expression of CEP72 mRNA CTD PMID:28341135 NCBI chr 1:29,225,312...29,255,294
Ensembl chr 1:29,225,361...29,255,271
JBrowse link
G Cep95 centrosomal protein 95 decreases expression EXP Methamphetamine results in decreased expression of CEP95 mRNA CTD PMID:19564919 NCBI chr10:91,732,111...91,760,095
Ensembl chr10:91,732,111...91,760,092
JBrowse link
G Cert1 ceramide transporter 1 increases expression EXP Methamphetamine results in increased expression of CERT1 mRNA CTD PMID:19564919 NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074
JBrowse link
G Cggbp1 CGG triplet repeat binding protein 1 increases expression EXP Methamphetamine results in increased expression of CGGBP1 mRNA CTD PMID:19564919 NCBI chr11:2,565,629...2,572,869
Ensembl chr11:2,565,484...2,573,031
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression EXP Methamphetamine results in increased expression of CHAC1 mRNA CTD PMID:28619521 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chat choline O-acetyltransferase decreases activity ISO Methamphetamine results in decreased activity of CHAT protein CTD PMID:10089005 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of CHD4 promoter
Methamphetamine results in increased expression of CHD4 mRNA
CTD PMID:26307267 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
JBrowse link
G Cherp calcium homeostasis endoplasmic reticulum protein increases expression ISO Methamphetamine results in increased expression of CHERP mRNA CTD PMID:26307267 NCBI chr16:17,367,455...17,380,507
Ensembl chr16:17,367,455...17,380,507
JBrowse link
G Chkb choline kinase beta increases expression ISO Methamphetamine results in increased expression of CHKB mRNA CTD PMID:26307267 NCBI chr 7:120,500,960...120,504,359
Ensembl chr 7:120,500,984...120,504,461
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CHORDC1 mRNA
Methamphetamine results in increased expression of CHORDC1 mRNA
CTD PMID:19564919 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit increases expression EXP Methamphetamine results in increased expression of CHRNB1 mRNA CTD PMID:19564919 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CHRNE mRNA
Methamphetamine results in increased expression of CHRNE mRNA
CTD PMID:19564919 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530
JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CHTF18 mRNA
Methamphetamine results in decreased expression of CHTF18 mRNA
CTD PMID:19564919 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 increases expression ISO Methamphetamine results in increased expression of CIAPIN1 mRNA CTD PMID:36914120 NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503
JBrowse link
G Cic capicua transcriptional repressor increases expression ISO Methamphetamine results in increased expression of CIC mRNA CTD PMID:26307267 NCBI chr 1:80,853,920...80,880,537
Ensembl chr 1:80,853,920...80,880,532
JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression EXP Methamphetamine results in increased expression of CIDEA mRNA; Methamphetamine results in increased expression of CIDEA protein CTD PMID:28341135 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression EXP Methamphetamine results in decreased expression of CIRBP mRNA CTD PMID:19564919 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression EXP Methamphetamine results in increased expression of CITED2 mRNA CTD PMID:19564919 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 multiple interactions
increases expression
decreases expression
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CITED4 mRNA
Methamphetamine results in increased expression of CITED4 mRNA
Methamphetamine results in decreased expression of CITED4 mRNA
CTD PMID:19564919 PMID:36914120 NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135
JBrowse link
G Ckap2 cytoskeleton associated protein 2 decreases expression EXP Methamphetamine results in decreased expression of CKAP2 mRNA CTD PMID:28341135 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Ckb creatine kinase B increases expression EXP Methamphetamine results in increased expression of CKB protein CTD PMID:19826936 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Clasrp CLK4-associating serine/arginine rich protein increases expression
decreases expression
ISO
EXP
Methamphetamine results in increased expression of SFRS16 mRNA
Methamphetamine results in decreased expression of CLASRP mRNA
CTD PMID:26307267 PMID:32035215 NCBI chr 1:79,232,260...79,256,462
Ensembl chr 1:79,232,261...79,256,354
JBrowse link
G Clcn6 chloride voltage-gated channel 6 increases expression ISO Methamphetamine results in increased expression of CLCN6 mRNA CTD PMID:26307267 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Clcnkb chloride voltage-gated channel Kb decreases expression
affects methylation
ISO Methamphetamine results in decreased expression of CLCNKB mRNA
Methamphetamine affects the methylation of CLCNKB promoter
CTD PMID:26307267 NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
JBrowse link
G Cldn5 claudin 5 decreases expression
multiple interactions
EXP
ISO
Methamphetamine results in decreased expression of CLDN5 mRNA
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein]
Methamphetamine results in decreased expression of CLDN5 mRNA; Methamphetamine results in decreased expression of CLDN5 protein
CTD PMID:19564919 PMID:35390362 PMID:36720452 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
JBrowse link
G Clec4e C-type lectin domain family 4, member E decreases expression ISO Methamphetamine results in decreased expression of CLEC4E mRNA CTD PMID:26307267 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
JBrowse link
G Clic4 chloride intracellular channel 4 increases expression EXP Methamphetamine results in increased expression of CLIC4 mRNA CTD PMID:19149911 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO
EXP
Methamphetamine results in increased expression of CLIP1 mRNA CTD PMID:19564919 PMID:26307267 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression EXP Methamphetamine results in increased expression of CLPX mRNA CTD PMID:19149911 NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082
JBrowse link
G Cluh clustered mitochondria homolog increases expression ISO Methamphetamine results in increased expression of CLUH mRNA CTD PMID:26307267 NCBI chr10:59,509,580...59,531,345
Ensembl chr10:59,509,726...59,531,345
JBrowse link
G Clvs2 clavesin 2 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of CLVS2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CLVS2 mRNA
CTD PMID:19564919 NCBI chr 1:23,735,660...23,842,685
Ensembl chr 1:23,735,272...23,842,692
JBrowse link
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 decreases methylation ISO Methamphetamine results in decreased methylation of CMTM3 promoter CTD PMID:26307267 NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790
JBrowse link
G Cmtm8 CKLF-like MARVEL transmembrane domain containing 8 decreases expression EXP Methamphetamine results in decreased expression of CMTM8 mRNA CTD PMID:19564919 NCBI chr 8:114,481,730...114,547,107
Ensembl chr 8:114,481,982...114,547,083
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like increases expression
multiple interactions
EXP Methamphetamine results in increased expression of CNOT6L mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CNOT6L mRNA
CTD PMID:19564919 NCBI chr14:13,410,499...13,502,511
Ensembl chr14:13,411,281...13,498,203
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase multiple interactions
decreases expression
ISO SNCA protein affects the reaction [Methamphetamine results in decreased expression of CNP protein]; TFEB protein inhibits the reaction [Methamphetamine results in decreased expression of CNP protein] CTD PMID:34562559 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Cnr1 cannabinoid receptor 1 affects response to substance EXP CNR1 protein affects the susceptibility to Methamphetamine CTD PMID:17953657 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cntfr ciliary neurotrophic factor receptor increases expression ISO Methamphetamine results in increased expression of CNTFR mRNA CTD PMID:26307267 NCBI chr 5:56,823,448...56,861,049
Ensembl chr 5:56,823,965...56,841,392
JBrowse link
G Cntn2 contactin 2 decreases expression EXP Methamphetamine results in decreased expression of CNTN2 mRNA CTD PMID:19564919 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887
JBrowse link
G Cntnap5b contactin associated protein family member 5B decreases expression ISO Methamphetamine results in decreased expression of CNTNAP5A mRNA CTD PMID:26307267 NCBI chr13:17,863,367...18,766,983
Ensembl chr13:18,093,420...18,761,014
JBrowse link
G Col10a1 collagen type X alpha 1 chain increases expression EXP Methamphetamine results in increased expression of COL10A1 mRNA CTD PMID:28341135 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases expression ISO Methamphetamine results in decreased expression of COL15A1 mRNA CTD PMID:36914120 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
JBrowse link
G Col25a1 collagen type XXV alpha 1 chain decreases expression ISO Methamphetamine results in decreased expression of COL25A1 mRNA CTD PMID:26307267 NCBI chr 2:218,755,152...219,154,348
Ensembl chr 2:218,755,691...219,153,501
JBrowse link
G Col28a1 collagen type XXVIII alpha 1 chain affects response to substance ISO COL28A1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 4:36,069,980...36,223,128
Ensembl chr 4:36,069,970...36,223,220
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP
ISO
Methamphetamine results in decreased expression of COL3A1 mRNA CTD PMID:19564919 PMID:36914120 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Col6a2 collagen type VI alpha 2 chain decreases expression ISO Methamphetamine results in decreased expression of COL6A2 mRNA CTD PMID:36914120 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
JBrowse link
G Comt catechol-O-methyltransferase increases response to substance
affects response to substance
ISO COMT gene polymorphism results in increased susceptibility to Methamphetamine
COMT gene polymorphism affects the susceptibility to Methamphetamine
CTD PMID:15274053 PMID:19462300 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Copb2 COPI coat complex subunit beta 2 increases expression EXP Methamphetamine results in increased expression of COPB2 mRNA CTD PMID:32035215 NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197
JBrowse link
G Coq10b coenzyme Q10B multiple interactions EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of COQ10B mRNA CTD PMID:19564919 NCBI chr 9:56,553,751...56,573,671
Ensembl chr 9:56,553,758...56,573,663
JBrowse link
G Coq8a coenzyme Q8A increases expression
decreases methylation
ISO Methamphetamine results in increased expression of COQ8A mRNA
Methamphetamine results in decreased methylation of COQ8A promoter
CTD PMID:26307267 NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
JBrowse link
G Corin corin, serine peptidase increases expression ISO Methamphetamine results in increased expression of CORIN mRNA CTD PMID:36914120 NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503
JBrowse link
G Coro6 coronin 6 increases expression ISO Methamphetamine results in increased expression of CORO6 mRNA CTD PMID:26307267 NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659
JBrowse link
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 increases expression ISO Methamphetamine results in increased expression of COX10 mRNA CTD PMID:26307267 NCBI chr10:48,630,993...48,742,805
Ensembl chr10:48,630,676...48,746,667
JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 increases expression ISO Methamphetamine results in increased expression of CPEB3 mRNA CTD PMID:26307267 NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560
JBrowse link
G Cplx1 complexin 1 increases expression EXP Methamphetamine results in increased expression of CPLX1 protein CTD PMID:19826936 NCBI chr14:1,184,677...1,216,392 JBrowse link
G Cplx2 complexin 2 increases expression EXP Methamphetamine results in increased expression of CPLX2 protein CTD PMID:19826936 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Cptp ceramide-1-phosphate transfer protein decreases methylation ISO Methamphetamine results in decreased methylation of CPTP promoter CTD PMID:26307267 NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017
JBrowse link
G Cpz carboxypeptidase Z increases expression EXP Methamphetamine results in increased expression of CPZ mRNA CTD PMID:15644446 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945
JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 decreases expression EXP Methamphetamine results in decreased expression of CRABP1 mRNA CTD PMID:32035215 NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases activity
increases expression
EXP
ISO
Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein
methamphetamine increases activity of Creb1 protein in the ventral tegmental area and nucleus accumbens
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 protein]
Methamphetamine results in increased expression of CREB1 mRNA; Methamphetamine results in increased expression of CREB1 protein
CTD
RGD
PMID:30742852 PMID:33421459 PMID:28782589 RGD:401900303 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 increases expression EXP Methamphetamine results in increased expression of CREB3L1 mRNA CTD PMID:35863504 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 increases expression EXP
ISO
Methamphetamine results in increased expression of CRELD2 mRNA CTD PMID:19564919 PMID:36914120 NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
JBrowse link
G Crem cAMP responsive element modulator multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CREM mRNA
Methamphetamine results in increased expression of CREM mRNA
CTD PMID:19564919 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of CRH mRNA
Methamphetamine results in increased expression of CRH mRNA
CTD PMID:19564919 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 multiple interactions EXP [CP 154526 binds to and results in decreased activity of CRHR1 protein] which results in decreased susceptibility to Methamphetamine CTD PMID:17119930 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CRISPLD1 mRNA
Methamphetamine results in decreased expression of CRISPLD1 mRNA
CTD PMID:19564919 NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926
JBrowse link
G Crk CRK proto-oncogene, adaptor protein decreases expression EXP Methamphetamine results in decreased expression of CRK protein CTD PMID:19826936 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein increases expression EXP Methamphetamine results in increased expression of CRKL mRNA CTD PMID:19564919 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 increases expression ISO Methamphetamine results in increased expression of CRTC2 mRNA CTD PMID:26307267 NCBI chr 2:175,709,603...175,719,768
Ensembl chr 2:175,709,644...175,719,763
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression EXP Methamphetamine results in decreased expression of CRY1 mRNA CTD PMID:19149911 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression EXP Methamphetamine results in increased expression of CRY2 mRNA CTD PMID:35863504 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965
JBrowse link
G Cryab crystallin, alpha B increases expression
multiple interactions
EXP Methamphetamine results in increased expression of CRYAB mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CRYAB mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CRYAB mRNA]
CTD PMID:19564919 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Crym crystallin, mu increases expression EXP Methamphetamine results in increased expression of CRYM protein CTD PMID:19826936 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
JBrowse link
G Cs citrate synthase increases expression EXP Methamphetamine results in increased expression of CS mRNA CTD PMID:19149911 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Csdc2 cold shock domain containing C2 increases expression ISO Methamphetamine results in increased expression of CSDC2 mRNA CTD PMID:36914120 NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463
JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO Methamphetamine results in increased expression of CSF1 mRNA CTD PMID:26307267 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression EXP Methamphetamine results in increased expression of CSF1R mRNA CTD PMID:32035215 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Methamphetamine results in increased expression of CSF2 mRNA CTD PMID:36914120 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 affects response to substance ISO CSMD1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
JBrowse link
G Csn1s1 casein alpha s1 increases expression EXP Methamphetamine results in increased expression of CSN1S1 mRNA CTD PMID:28341135 NCBI chr14:20,343,620...20,359,614
Ensembl chr14:20,343,619...20,359,614
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of CSRP2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CSRP2 mRNA
CTD PMID:19564919 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Cst11 cystatin 11 increases methylation ISO Methamphetamine results in increased methylation of CST11 promoter CTD PMID:26307267 NCBI chr 3:136,211,414...136,214,138
Ensembl chr 3:136,211,414...136,214,138
JBrowse link
G Cstb cystatin B affects expression EXP Methamphetamine affects the expression of CSTB protein CTD PMID:17904249 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Ctbp2 C-terminal binding protein 2 decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of CTBP2 promoter
Methamphetamine results in increased expression of CTBP2 mRNA
CTD PMID:26307267 NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression
EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of CTNNB1 mRNA] CTD PMID:19149911 PMID:32035215 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctrl chymotrypsin-like increases expression EXP Methamphetamine results in increased expression of CTRL mRNA CTD PMID:19564919 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626
JBrowse link
G Ctsb cathepsin B increases activity EXP Methamphetamine results in increased activity of CTSB protein CTD PMID:34374793 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D affects localization EXP Methamphetamine affects the localization of CTSD protein CTD PMID:17105920 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cubn cubilin affects response to substance ISO CUBN gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
JBrowse link
G Cuedc1 CUE domain containing 1 increases expression ISO Methamphetamine results in increased expression of CUEDC1 mRNA CTD PMID:26307267 NCBI chr10:72,892,637...72,986,546
Ensembl chr10:72,892,637...72,986,542
JBrowse link
G Cul2 cullin 2 decreases expression EXP Methamphetamine results in decreased expression of CUL2 mRNA CTD PMID:19564919 NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968
JBrowse link
G Cul9 cullin 9 increases expression ISO Methamphetamine results in increased expression of CUL9 mRNA CTD PMID:26307267 NCBI chr 9:14,435,948...14,479,552
Ensembl chr 9:14,436,111...14,479,548
JBrowse link
G Cux1 cut-like homeobox 1 increases expression EXP Methamphetamine results in increased expression of CUX1 mRNA CTD PMID:19564919 NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
JBrowse link
G Cwc25 CWC25 spliceosome-associated protein homolog increases expression EXP Methamphetamine results in increased expression of CWC25 mRNA CTD PMID:19564919 NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases expression EXP Methamphetamine results in decreased expression of CX3CR1 mRNA CTD PMID:19564919 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Methamphetamine results in increased expression of CXCL10 mRNA CTD PMID:25290377 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
increases expression
EXP Luteolin inhibits the reaction [Methamphetamine results in increased expression of CXCL12 mRNA] CTD PMID:32035215 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO Methamphetamine results in increased expression of CXCL2 mRNA CTD PMID:25290377 PMID:36914120 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Methamphetamine results in increased expression of CXCL1 mRNA CTD PMID:36914120 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyb5b cytochrome b5 type B increases expression EXP Methamphetamine results in increased expression of CYB5B mRNA CTD PMID:19149911 NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein] CTD PMID:27565679 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cycs cytochrome c, somatic increases expression EXP Methamphetamine results in increased expression of CYCS mRNA CTD PMID:19149911 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression EXP Methamphetamine results in increased expression of CYP11A1 mRNA CTD PMID:19149911 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing ISO CYP1A2 protein affects the metabolism of Methamphetamine metabolite CTD PMID:16038959 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of CYP27A1 mRNA] CTD PMID:19149911 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects response to substance
increases metabolic processing
ISO CYP2D4 gene polymorphism affects the susceptibility to Methamphetamine; CYP2D6 protein affects the susceptibility to Methamphetamine
CYP2D6 protein results in increased metabolism of Methamphetamine
CTD PMID:18280655 PMID:20727252 PMID:27320963 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing ISO CYP2E1 protein affects the metabolism of Methamphetamine metabolite CTD PMID:16038959 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CYP2J10 mRNA
Methamphetamine results in decreased expression of CYP2J10 mRNA
CTD PMID:19564919 NCBI chr 5:110,960,319...110,995,220
Ensembl chr 5:110,960,317...110,995,115
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 decreases expression EXP Methamphetamine results in decreased expression of CYP2T1 mRNA CTD PMID:19564919 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
multiple interactions
ISO CYP3A4 protein affects the metabolism of Methamphetamine metabolite
[Methamphetamine binds to CYP3A4 promoter] which results in increased expression of CYP3A4 mRNA
CTD PMID:12851153 PMID:16038959 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 increases expression EXP Methamphetamine results in increased expression of CYP4A8 mRNA CTD PMID:15644446 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 decreases expression EXP Methamphetamine results in decreased expression of CYP4F4 mRNA CTD PMID:19564919 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Methamphetamine results in decreased expression of CYP7B1 mRNA CTD PMID:35688268 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Cyth1 cytohesin 1 increases expression ISO Methamphetamine results in increased expression of CYTH1 mRNA CTD PMID:26307267 NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760
JBrowse link
G Cyyr1 cysteine and tyrosine rich 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of CYYR1 mRNA
Methamphetamine results in decreased expression of CYYR1 mRNA
CTD PMID:19564919 NCBI chr11:24,557,620...24,664,007
Ensembl chr11:24,515,316...24,663,961
JBrowse link
G Czib CXXC motif containing zinc binding protein decreases expression EXP Methamphetamine results in decreased expression of CZIB mRNA CTD PMID:19564919 NCBI chr 5:122,648,333...122,657,767
Ensembl chr 5:122,648,411...122,656,910
JBrowse link
G Dad1 defender against cell death 1 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of DAD1 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DAD1 mRNA]
CTD PMID:19564919 NCBI chr15:27,677,286...27,697,120
Ensembl chr15:27,677,268...27,697,347
JBrowse link
G Dbh dopamine beta-hydroxylase decreases expression EXP Methamphetamine results in decreased expression of DBH protein CTD PMID:28661099 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression
decreases expression
affects expression
ISO
EXP
Methamphetamine results in increased expression of DBP mRNA
Methamphetamine results in decreased expression of DBP mRNA
Methamphetamine affects the expression of DBP mRNA
CTD PMID:26307267 PMID:35863504 PMID:36914120 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein affects response to substance ISO DCSTAMP gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
JBrowse link
G Dctn1 dynactin subunit 1 decreases expression EXP Methamphetamine results in decreased expression of DCTN1 mRNA; Methamphetamine results in decreased expression of DCTN1 protein CTD PMID:34374793 NCBI chr 4:115,671,024...115,703,824
Ensembl chr 4:115,661,638...115,703,815
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 affects expression EXP Methamphetamine affects the expression of DDAH1 protein CTD PMID:17904249 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
affects localization
increases expression
EXP
ISO
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; [Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT3 mRNA; DDIT3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BBC3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BCL2L11 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Methamphetamine promotes the reaction [FOXO3 protein binds to DDIT3 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]
Methamphetamine affects the localization of DDIT3 protein
Methamphetamine results in increased expression of DDIT3 mRNA; Methamphetamine results in increased expression of DDIT3 protein
ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]
CTD PMID:15644446 PMID:19564919 PMID:27323860 PMID:28070110 PMID:28619521 More... NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression
increases response to substance
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT4 mRNA; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of PARP1 protein modified form]
DDIT4 protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein]
Methamphetamine results in increased expression of DDIT4 mRNA; Methamphetamine results in increased expression of DDIT4 protein
DDIT4 protein results in increased susceptibility to Methamphetamine
CTD PMID:19564919 PMID:26825372 PMID:31059759 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddt D-dopachrome tautomerase affects expression EXP Methamphetamine affects the expression of DDT protein CTD PMID:17904249 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482
JBrowse link
G Ddx10 DEAD-box helicase 10 increases expression EXP Methamphetamine results in increased expression of DDX10 mRNA CTD PMID:19149911 NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373
JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO Methamphetamine results in increased expression of DDX17 mRNA CTD PMID:26307267 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Ddx21 DExD-box helicase 21 multiple interactions
decreases expression
EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of DDX21 mRNA] CTD PMID:19149911 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Ddx52 DExD-box helicase 52 decreases expression EXP Methamphetamine results in decreased expression of DDX52 mRNA CTD PMID:19564919 NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266
JBrowse link
G Deaf1 DEAF1 transcription factor increases expression ISO Methamphetamine results in increased expression of DEAF1 mRNA CTD PMID:26307267 NCBI chr 1:196,401,857...196,435,541
Ensembl chr 1:196,401,857...196,435,541
JBrowse link
G Dennd5a DENN domain containing 5A increases expression ISO Methamphetamine results in increased expression of DENND5A mRNA CTD PMID:26307267 NCBI chr 1:163,928,183...163,994,207
Ensembl chr 1:163,928,183...163,994,316
JBrowse link
G Depdc1 DEP domain containing 1 decreases expression EXP Methamphetamine results in decreased expression of DEPDC1 mRNA CTD PMID:28341135 NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
JBrowse link
G Depp1 DEPP autophagy regulator 1 decreases expression ISO Methamphetamine results in decreased expression of DEPP1 mRNA CTD PMID:36914120 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 increases expression EXP Methamphetamine results in increased expression of DGAT2 mRNA CTD PMID:35863504 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dgkb diacylglycerol kinase, beta decreases expression EXP Methamphetamine results in decreased expression of DGKB mRNA CTD PMID:32035215 NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043
JBrowse link
G Dgkg diacylglycerol kinase, gamma increases expression ISO Methamphetamine results in increased expression of DGKG mRNA CTD PMID:26307267 NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
JBrowse link
G Dgkh diacylglycerol kinase, eta increases expression ISO Methamphetamine results in increased expression of DGKH mRNA CTD PMID:26307267 NCBI chr15:53,981,079...54,150,470
Ensembl chr15:53,991,481...54,150,706
JBrowse link
G Dgkz diacylglycerol kinase zeta increases expression ISO Methamphetamine results in increased expression of DGKZ mRNA CTD PMID:26307267 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression EXP Methamphetamine results in increased expression of DHCR24 mRNA CTD PMID:35863504 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhx16 DEAH-box helicase 16 increases expression ISO Methamphetamine results in increased expression of DHX16 mRNA CTD PMID:26307267 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
JBrowse link
G Diaph3 diaphanous-related formin 3 decreases expression EXP Methamphetamine results in decreased expression of DIAPH3 mRNA CTD PMID:28341135 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
JBrowse link
G Dicer1 dicer 1 ribonuclease III increases methylation ISO Methamphetamine results in increased methylation of DICER1 promoter CTD PMID:26307267 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression EXP Methamphetamine results in increased expression of DIO2 mRNA CTD PMID:19149911 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dipk1a divergent protein kinase domain 1A decreases expression EXP Methamphetamine results in decreased expression of DIPK1A mRNA CTD PMID:19564919 NCBI chr14:1,772,412...1,843,508
Ensembl chr14:1,772,422...1,843,743
JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease increases expression EXP Methamphetamine results in increased expression of DIS3 mRNA CTD PMID:19564919 NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642
JBrowse link
G Dis3l DIS3-like exosome 3'-5' exoribonuclease increases expression ISO Methamphetamine results in increased expression of DIS3L mRNA CTD PMID:26307267 NCBI chr 8:64,803,925...64,840,306
Ensembl chr 8:64,803,927...64,840,165
JBrowse link
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 increases expression EXP Methamphetamine results in increased expression of DIS3L2 mRNA CTD PMID:32035215 NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO Methamphetamine results in increased expression of DKK1 mRNA CTD PMID:25290377 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression EXP Methamphetamine results in decreased expression of DLAT protein CTD PMID:19826936 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression EXP Methamphetamine results in increased expression of DLD protein CTD PMID:19826936 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of DLG4 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of DLG4 protein]
CTD PMID:33421459 PMID:34461196 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression ISO Methamphetamine results in decreased expression of DLGAP5 mRNA CTD PMID:25290377 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of DLST mRNA; Methamphetamine results in decreased expression of DLST protein
Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of DLST mRNA]
CTD PMID:19149911 PMID:19826936 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
JBrowse link
G Dmd dystrophin increases expression ISO Methamphetamine results in increased expression of DMD mRNA CTD PMID:26307267 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dmkn dermokine increases expression
decreases expression
EXP Methamphetamine results in increased expression of DMKN mRNA
Methamphetamine results in decreased expression of DMKN mRNA
CTD PMID:19564919 PMID:32035215 NCBI chr 1:86,013,237...86,031,243
Ensembl chr 1:86,014,188...86,030,006
JBrowse link
G Dmpk DM1 protein kinase increases expression ISO Methamphetamine results in increased expression of DMPK mRNA CTD PMID:26307267 NCBI chr 1:78,730,255...78,740,585
Ensembl chr 1:78,730,275...78,740,593
JBrowse link
G Dmwd DM1 locus, WD repeat containing increases expression ISO Methamphetamine results in increased expression of DMWD mRNA CTD PMID:26307267 NCBI chr 1:78,722,436...78,729,224
Ensembl chr 1:78,722,330...78,740,593
JBrowse link
G Dnaaf2 dynein, axonemal, assembly factor 2 increases expression EXP Methamphetamine results in increased expression of DNAAF2 mRNA CTD PMID:19564919 NCBI chr 6:87,661,101...87,670,267
Ensembl chr 6:87,660,821...87,670,199
JBrowse link
G Dnah1 dynein, axonemal, heavy chain 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of DNAH1 mRNA
Methamphetamine results in decreased expression of DNAH1 mRNA
CTD PMID:19564919 NCBI chr16:6,455,514...6,517,103
Ensembl chr16:6,456,002...6,518,350
JBrowse link
G Dnah6 dynein, axonemal, heavy chain 6 affects expression EXP Methamphetamine affects the expression of DNAH6 mRNA CTD PMID:35863504 NCBI chr 4:105,064,123...105,284,361
Ensembl chr 4:105,064,125...105,284,376
JBrowse link
G Dnai1 dynein, axonemal, intermediate chain 1 increases expression EXP Methamphetamine results in increased expression of DNAI1 mRNA CTD PMID:34374793 NCBI chr 5:56,730,179...56,800,926
Ensembl chr 5:56,730,179...56,800,925
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJA1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJA1 mRNA] CTD PMID:19564919 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 increases expression EXP Methamphetamine results in increased expression of DNAJA4 mRNA CTD PMID:19564919 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB1 mRNA] CTD PMID:19564919 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB4 mRNA
Methamphetamine results in increased expression of DNAJB4 mRNA
CTD PMID:19564919 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of DNAJB5 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB5 mRNA]
CTD PMID:19564919 PMID:36914120 NCBI chr 5:57,176,840...57,186,067
Ensembl chr 5:57,176,845...57,185,490
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of DNAJC3 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJC3 mRNA]
CTD PMID:19564919 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dnal4 dynein, axonemal, light chain 4 decreases expression EXP Methamphetamine results in decreased expression of DNAL4 mRNA CTD PMID:19564919 NCBI chr 7:111,312,424...111,325,283
Ensembl chr 7:111,312,427...111,325,283
JBrowse link
G Dnase1 deoxyribonuclease 1 increases expression
decreases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of DNASE1 mRNA
Methamphetamine results in decreased expression of DNASE1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of DNASE1 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Dnm1 dynamin 1 increases expression ISO Methamphetamine results in increased expression of DNM1 mRNA CTD PMID:26307267 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression
increases expression
EXP Methamphetamine results in decreased expression of DNMT1 mRNA
Methamphetamine results in increased expression of DNMT1 mRNA
CTD PMID:17254711 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dock6 dedicator of cytokinesis 6 increases expression ISO Methamphetamine results in increased expression of DOCK6 mRNA CTD PMID:26307267 NCBI chr 8:20,342,430...20,394,660
Ensembl chr 8:20,342,089...20,394,552
JBrowse link
G Dok3 docking protein 3 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of DOK3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of DOK3 mRNA
CTD PMID:19564919 NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188
JBrowse link
G Dolk dolichol kinase decreases expression EXP Methamphetamine results in decreased expression of DOLK mRNA CTD PMID:19564919 NCBI chr 3:13,557,826...13,559,864
Ensembl chr 3:13,557,817...13,559,917
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 affects expression EXP Methamphetamine affects the expression of DPYSL2 protein CTD PMID:19826936 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression EXP Methamphetamine results in decreased expression of DPYSL3 protein CTD PMID:19826936 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
JBrowse link
G Dpysl5 dihydropyrimidinase-like 5 increases expression EXP Methamphetamine results in increased expression of DPYSL5 protein CTD PMID:19826936 NCBI chr 6:25,575,104...25,659,422
Ensembl chr 6:25,575,104...25,659,422
JBrowse link
G Drd1 dopamine receptor D1 increases expression
decreases expression
multiple interactions
affects activity
increases response to substance
ISO
EXP
Methamphetamine results in increased expression of DRD1 protein
Methamphetamine results in decreased expression of DRD1 protein
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD1 protein]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [SCH 23390 binds to DRD1 protein]
DRD1 protein results in increased susceptibility to Methamphetamine
[SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; bisphenol A promotes the reaction [DRD1 protein results in increased susceptibility to Methamphetamine]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]
CTD PMID:2891082 PMID:11126397 PMID:11701771 PMID:12617968 PMID:18363855 More... NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 increases response to substance
decreases expression
multiple interactions
increases activity
affects activity
ISO
EXP
DRD2 gene polymorphism results in increased susceptibility to Methamphetamine
Methamphetamine results in decreased expression of DRD2 protein
[Sulpiride binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Methamphetamine; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]
Methamphetamine results in increased activity of DRD2 protein
Methamphetamine affects the activity of DRD2 protein
DRD2 gene results in increased susceptibility to Methamphetamine
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD2 protein]; [Aripiprazole binds to and results in increased activity of DRD2 protein] which results in increased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [Sulpiride binds to DRD2 protein]
CTD PMID:2891082 PMID:11126397 PMID:11729018 PMID:17327886 PMID:18363855 More... NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 decreases expression
increases activity
ISO
EXP
Methamphetamine results in decreased expression of DRD3 protein
Methamphetamine results in increased activity of DRD3 protein
CTD PMID:19046384 PMID:19940168 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 affects response to substance
multiple interactions
increases response to substance
ISO DRD4 gene polymorphism affects the susceptibility to Methamphetamine
[NRA 0160 binds to and results in decreased activity of DRD4 protein] which results in decreased susceptibility to Methamphetamine
DRD4 gene polymorphism results in increased susceptibility to Methamphetamine
CTD PMID:10579464 PMID:15274053 PMID:19462300 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Dsp desmoplakin increases expression ISO Methamphetamine results in increased expression of DSP mRNA CTD PMID:26307267 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
JBrowse link
G Dspp dentin sialophosphoprotein increases expression EXP Methamphetamine results in increased expression of DSPP mRNA CTD PMID:15644446 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
JBrowse link
G Dst dystonin increases expression ISO Methamphetamine results in increased expression of DST mRNA CTD PMID:26307267 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Methamphetamine results in decreased expression of DTL mRNA CTD PMID:25290377 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
JBrowse link
G Dtx3 deltex E3 ubiquitin ligase 3 increases expression
increases methylation
ISO Methamphetamine results in increased expression of DTX3 mRNA
Methamphetamine results in increased methylation of DTX3 promoter
CTD PMID:26307267 NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions
increases expression
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP1 mRNA; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA] CTD PMID:11701771 PMID:19564919 PMID:26307267 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp11 dual specificity phosphatase 11 increases expression EXP Methamphetamine results in increased expression of DUSP11 mRNA CTD PMID:19564919 NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181
JBrowse link
G Dusp14 dual specificity phosphatase 14 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP14 mRNA
Methamphetamine results in increased expression of DUSP14 mRNA
CTD PMID:19564919 NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression EXP Methamphetamine results in increased expression of DUSP5 mRNA CTD PMID:19564919 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions
increases expression
EXP [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA] CTD PMID:11701771 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dut deoxyuridine triphosphatase increases expression EXP Methamphetamine results in increased expression of DUT mRNA CTD PMID:19149911 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Dux4 double homeobox 4 decreases expression EXP Methamphetamine results in decreased expression of DUXBL1 mRNA CTD PMID:19564919 NCBI chr16:1,558,430...1,570,045
Ensembl chr16:1,558,766...1,568,565
JBrowse link
G Dydc2 DPY30 domain containing 2 increases expression EXP Methamphetamine results in increased expression of DYDC2 mRNA CTD PMID:28341135 NCBI chr16:16,928,172...16,941,950
Ensembl chr16:16,928,194...16,936,164
JBrowse link
G Dysf dysferlin increases expression ISO Methamphetamine results in increased expression of DYSF mRNA CTD PMID:26307267 NCBI chr 4:116,490,877...116,690,709
Ensembl chr 4:116,490,616...116,690,709
JBrowse link
G Ebi3 Epstein-Barr virus induced 3 decreases expression ISO Methamphetamine results in decreased expression of EBI3 mRNA CTD PMID:26307267 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
JBrowse link
G Echdc2 enoyl CoA hydratase domain containing 2 increases expression ISO Methamphetamine results in increased expression of ECHDC2 mRNA CTD PMID:26307267 NCBI chr 5:122,915,874...122,934,860
Ensembl chr 5:122,916,134...122,934,859
JBrowse link
G Echdc3 enoyl CoA hydratase domain containing 3 decreases expression ISO Methamphetamine results in decreased expression of ECHDC3 mRNA CTD PMID:26307267 NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516
JBrowse link
G Ect2 epithelial cell transforming 2 decreases expression EXP Methamphetamine results in decreased expression of ECT2 mRNA CTD PMID:28341135 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
JBrowse link
G Edc4 enhancer of mRNA decapping 4 increases expression ISO Methamphetamine results in increased expression of EDC4 mRNA CTD PMID:26307267 NCBI chr19:33,774,062...33,786,054
Ensembl chr19:33,774,055...33,787,758
JBrowse link
G Edn3 endothelin 3 multiple interactions
increases expression
EXP
ISO
GATA4 protein affects the reaction [Methamphetamine results in increased expression of EDN3 mRNA] CTD PMID:36914120 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases methylation ISO Methamphetamine results in decreased methylation of EEF2K promoter CTD PMID:26307267 NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164
JBrowse link
G Efnb1 ephrin B1 increases expression EXP Methamphetamine results in increased expression of EFNB1 mRNA CTD PMID:19564919 NCBI chr  X:64,257,351...64,270,158
Ensembl chr  X:64,257,351...64,270,157
JBrowse link
G Egfl7 EGF-like-domain, multiple 7 multiple interactions
increases expression
decreases expression
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFL7 mRNA
Methamphetamine results in increased expression of EGFL7 mRNA
Methamphetamine results in decreased expression of EGFL7 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879
JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of EGFLAM mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFLAM mRNA
CTD PMID:19564919 NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression ISO Methamphetamine results in increased expression of EGLN3 mRNA CTD PMID:36914120 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
EXP
ISO
CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]
Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]]
CTD PMID:11754491 PMID:15644446 PMID:19564919 PMID:20184921 PMID:20298714 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 increases expression EXP Methamphetamine results in increased expression of EGR2 mRNA CTD PMID:15644446 PMID:19564919 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Egr4 early growth response 4 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of EGR4 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of EGR4 mRNA
CTD PMID:19564919 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
JBrowse link
G Ehbp1l1 EH domain binding protein 1-like 1 increases expression ISO Methamphetamine results in increased expression of EHBP1L1 mRNA CTD PMID:26307267 NCBI chr 1:202,994,115...203,014,320
Ensembl chr 1:202,994,118...203,014,270
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 increases expression ISO Methamphetamine results in increased expression of EHMT2 mRNA CTD PMID:26307267 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression EXP Methamphetamine results in increased expression of EIF1A mRNA CTD PMID:19564919 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
increases expression
EXP
ISO
CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of EIF2AK3 protein modified form]
CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]
CTD PMID:27323860 PMID:28070110 PMID:29705343 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
EXP Methamphetamine results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein]
CTD PMID:28070110 PMID:34214594 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Methamphetamine inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:19054297 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 increases expression EXP Methamphetamine results in increased expression of EIF4G2 mRNA CTD PMID:10336889 NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 increases expression EXP Methamphetamine results in increased expression of ELP1 mRNA CTD PMID:19564919 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Eml1 EMAP like 1 increases expression EXP Methamphetamine results in increased expression of EML1 mRNA CTD PMID:32035215 NCBI chr 6:127,283,968...127,457,246
Ensembl chr 6:127,284,029...127,457,246
JBrowse link
G Eml2 EMAP like 2 increases expression ISO Methamphetamine results in increased expression of EML2 mRNA CTD PMID:26307267 NCBI chr 1:78,827,595...78,859,342
Ensembl chr 1:78,828,080...78,859,341
JBrowse link
G Emsy EMSY transcriptional repressor, BRCA2 interacting increases expression ISO Methamphetamine results in increased expression of EMSY mRNA CTD PMID:26307267 NCBI chr 1:152,881,485...152,960,420
Ensembl chr 1:152,883,992...152,953,528
JBrowse link
G Eno1 enolase 1 decreases expression EXP Methamphetamine results in decreased expression of ENO1 protein CTD PMID:19826936 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Eno2 enolase 2 increases expression EXP Methamphetamine results in increased expression of ENO2 protein CTD PMID:19826936 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression ISO Methamphetamine results in decreased expression of ENPP1 mRNA CTD PMID:26307267 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Enpp6 ectonucleotide pyrophosphatase/phosphodiesterase 6 decreases expression EXP Methamphetamine results in decreased expression of ENPP6 mRNA CTD PMID:28619521 NCBI chr16:45,165,883...45,294,126
Ensembl chr16:45,169,178...45,294,077
JBrowse link
G Ep400 E1A binding protein p400 increases expression ISO Methamphetamine results in increased expression of EP400 mRNA CTD PMID:26307267 NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression EXP Methamphetamine results in increased expression of EPAS1 mRNA CTD PMID:32035215 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epb41l1 erythrocyte membrane protein band 4.1-like 1 decreases methylation ISO Methamphetamine results in decreased methylation of EPB41L1 promoter CTD PMID:26307267 NCBI chr 3:144,929,195...145,052,723
Ensembl chr 3:144,984,640...145,052,721
JBrowse link
G Epcam epithelial cell adhesion molecule decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of EPCAM mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EPCAM mRNA
CTD PMID:19564919 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions
increases methylation
ISO Methamphetamine results in increased expression of EPHX1 mRNA; Methamphetamine results in increased expression of EPHX1 protein
EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Methamphetamine promotes the reaction [PRKCD protein modified form binds to EPHX1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of EPHX1 protein]
Methamphetamine results in increased methylation of EPHX1 promoter
CTD PMID:26307267 PMID:31422080 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Epor erythropoietin receptor decreases expression EXP Methamphetamine results in decreased expression of EPOR mRNA CTD PMID:15644446 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression
increases phosphorylation
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of ERN1 protein modified form
Methamphetamine results in increased phosphorylation of ERN1 protein
ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein]
Melatonin inhibits the reaction [Methamphetamine results in increased expression of ERN1 protein modified form]
CTD PMID:27323860 PMID:28070110 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of ERRFI1 mRNA
Methamphetamine results in increased expression of ERRFI1 mRNA
CTD PMID:19564919 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Esr1 estrogen receptor 1 increases response to substance ISO ESR1 gene polymorphism results in increased susceptibility to Methamphetamine CTD PMID:19386276 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Etl4 enhancer trap locus 4 increases expression ISO Methamphetamine results in increased expression of ETL4 mRNA CTD PMID:26307267 NCBI chr17:82,841,075...83,304,868
Ensembl chr17:82,495,041...83,304,715
JBrowse link
G Evc2 EvC ciliary complex subunit 2 increases expression EXP Methamphetamine results in increased expression of EVC2 mRNA CTD PMID:28341135 NCBI chr14:73,366,832...73,454,539
Ensembl chr14:73,367,963...73,454,516
JBrowse link
G Exoc7 exocyst complex component 7 decreases expression EXP Methamphetamine results in decreased expression of EXOC7 mRNA CTD PMID:19564919 NCBI chr10:101,521,630...101,540,425
Ensembl chr10:101,520,927...101,540,561
JBrowse link
G F11r F11 receptor multiple interactions
increases expression
EXP Luteolin inhibits the reaction [Methamphetamine results in increased expression of F11R mRNA] CTD PMID:32035215 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402
JBrowse link
G F3 coagulation factor III, tissue factor increases methylation ISO Methamphetamine results in increased methylation of F3 promoter CTD PMID:26307267 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of FAAH mRNA
Methamphetamine results in decreased expression of FAAH mRNA
CTD PMID:19564919 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
JBrowse link
G Fabp3 fatty acid binding protein 3 affects response to substance
increases expression
ISO FABP3 affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of FABP3 mRNA
CTD PMID:20181611 PMID:25290377 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
G Fabp7 fatty acid binding protein 7 affects expression EXP Methamphetamine affects the expression of FABP7 protein CTD PMID:17904249 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
JBrowse link
G Fah fumarylacetoacetate hydrolase decreases expression EXP Methamphetamine results in decreased expression of FAH mRNA CTD PMID:19564919 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
JBrowse link
G Fam110a family with sequence similarity 110, member A decreases expression EXP Methamphetamine results in decreased expression of FAM110A mRNA CTD PMID:19564919 NCBI chr 3:140,474,484...140,485,074
Ensembl chr 3:140,474,249...140,485,093
JBrowse link
G Fam193a family with sequence similarity 193, member A increases expression ISO Methamphetamine results in increased expression of FAM193A mRNA CTD PMID:26307267 NCBI chr14:76,250,103...76,382,525
Ensembl chr14:76,256,161...76,382,514
JBrowse link
G Fam193b family with sequence similarity 193, member B increases expression ISO Methamphetamine results in increased expression of FAM193B mRNA CTD PMID:26307267 NCBI chr17:9,066,818...9,099,511
Ensembl chr17:9,066,707...9,099,508
JBrowse link
G Fank1 fibronectin type III and ankyrin repeat domains 1 decreases expression EXP Methamphetamine results in decreased expression of FANK1 mRNA CTD PMID:19564919 NCBI chr 1:188,577,512...188,685,501
Ensembl chr 1:188,577,575...188,685,504
JBrowse link
G Fas Fas cell surface death receptor decreases expression
increases expression
EXP Methamphetamine results in decreased expression of FAS mRNA
Methamphetamine results in increased expression of FAS mRNA
CTD PMID:15644446 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression EXP Methamphetamine results in increased expression of FASLG mRNA; Methamphetamine results in increased expression of FASLG protein CTD PMID:15644446 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fastkd3 FAST kinase domains 3 decreases expression ISO Methamphetamine results in decreased expression of FASTKD3 mRNA CTD PMID:26307267 NCBI chr 1:34,858,342...34,866,988
Ensembl chr 1:34,858,219...34,866,973
JBrowse link
G Fblim1 filamin binding LIM protein 1 increases expression EXP Methamphetamine results in increased expression of FBLIM1 mRNA CTD PMID:19564919 NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 decreases expression EXP Methamphetamine results in decreased expression of FBXL4 mRNA CTD PMID:19564919 NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443
JBrowse link
G Fbxo28 F-box protein 28 increases expression EXP Methamphetamine results in increased expression of FBXO28 mRNA CTD PMID:19564919 NCBI chr13:93,995,993...94,021,464
Ensembl chr13:93,995,996...94,021,464
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO Methamphetamine results in increased expression of FBXO32 mRNA CTD PMID:23933405 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fbxo33 F-box protein 33 increases expression EXP Methamphetamine results in increased expression of FBXO33 mRNA CTD PMID:19564919 NCBI chr 6:76,900,619...76,934,232
Ensembl chr 6:76,900,631...76,932,669
JBrowse link
G Fcgbp Fc gamma binding protein decreases expression ISO Methamphetamine results in decreased expression of FCGBP mRNA CTD PMID:26307267 NCBI chr 1:83,374,979...83,413,082
Ensembl chr 1:83,372,127...83,413,083
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression EXP Methamphetamine results in increased expression of FGF2 mRNA CTD PMID:19564919 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf4 fibroblast growth factor 4 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of FGF4 mRNA
Methamphetamine results in increased expression of FGF4 mRNA
CTD PMID:19564919 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO Methamphetamine results in increased expression of FGFR3 mRNA CTD PMID:26307267 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase affects response to substance ISO FHIT gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Fjx1 four-jointed box kinase 1 decreases expression EXP Methamphetamine results in decreased expression of FJX1 mRNA CTD PMID:19564919 NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321
JBrowse link
G Fkbp15 FKBP prolyl isomerase family member 15 affects response to substance ISO FKBP15 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression EXP Methamphetamine results in increased expression of FKBP4 mRNA CTD PMID:19149911 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Flna filamin A increases expression ISO Methamphetamine results in increased expression of FLNA mRNA CTD PMID:26307267 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Flnb filamin B increases expression ISO Methamphetamine results in increased expression of FLNB mRNA CTD PMID:26307267 NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
JBrowse link
G Flnc filamin C increases expression ISO Methamphetamine results in increased expression of FLNC mRNA CTD PMID:26307267 PMID:36914120 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression ISO
EXP
Methamphetamine results in increased expression of FLT1 mRNA CTD PMID:26307267 PMID:32035215 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of FMO2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of FMO2 mRNA
CTD PMID:19564919 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases metabolic processing ISO FMO3 protein results in increased metabolism of Methamphetamine CTD PMID:27320963 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Fn1 fibronectin 1 increases expression ISO Methamphetamine results in increased expression of FN1 mRNA CTD PMID:12766323 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
affects response to substance
ISO
EXP
Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]; FOS protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Idazoxan inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]]; Lidocaine inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]]
Methamphetamine results in increased expression of FOS mRNA; Methamphetamine results in increased expression of FOS protein
[Methamphetamine co-treated with SCH 23390] results in increased expression of FOS mRNA; Carbamazepine inhibits the reaction [Methamphetamine results in increased expression of FOS protein]; Oxytocin inhibits the reaction [Methamphetamine results in increased expression of FOS protein]
Methamphetamine results in increased expression of FOS; Methamphetamine results in increased expression of FOS protein
FOS mRNA affects the susceptibility to Methamphetamine; FOS protein affects the susceptibility to Methamphetamine
CTD PMID:10559418 PMID:10731628 PMID:11754491 PMID:12050851 PMID:19564919 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO methamphetamine increases expression of Fosb protein in the ventral tegmental area and nucleus accumbens RGD PMID:28782589 RGD:401900303 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression EXP Methamphetamine results in increased expression of FOSL1 mRNA CTD PMID:19564919 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxe1 forkhead box E1 increases expression EXP Methamphetamine results in increased expression of FOXE1 mRNA; Methamphetamine results in increased expression of FOXE1 protein CTD PMID:28341135 NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835
JBrowse link
G Foxo3 forkhead box O3 decreases phosphorylation
increases phosphorylation
multiple interactions
affects localization
EXP Methamphetamine results in decreased phosphorylation of FOXO3 protein
Methamphetamine results in increased phosphorylation of FOXO3 protein
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]; Methamphetamine promotes the reaction [FOXO3 protein binds to DDIT3 protein]
Methamphetamine affects the localization of FOXO3 protein
CTD PMID:34214594 PMID:35863504 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Fst follistatin decreases expression EXP Methamphetamine results in decreased expression of FST mRNA CTD PMID:28619521 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of FTCD mRNA
Methamphetamine results in increased expression of FTCD mRNA
CTD PMID:19564919 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
JBrowse link
G Fuz fuzzy planar cell polarity protein increases expression ISO Methamphetamine results in increased expression of FUZ mRNA CTD PMID:26307267 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Methamphetamine results in increased expression of FYN mRNA CTD PMID:26307267 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 increases methylation ISO Methamphetamine results in increased methylation of GABARAPL2 promoter CTD PMID:26307267 NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628
Ensembl chr 8:39,910,534...39,924,628
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions ISO Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] CTD PMID:21729720 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha increases expression
multiple interactions
EXP Methamphetamine results in increased expression of GABPA mRNA
Lithium inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA]
CTD PMID:19149911 NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] CTD PMID:21729720 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 increases response to substance
multiple interactions
ISO GABRG2 gene results in increased susceptibility to Methamphetamine
Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]
CTD PMID:15772696 PMID:21729720 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 increases expression EXP Methamphetamine results in increased expression of GABRG3 mRNA CTD PMID:15644446 NCBI chr 1:107,627,450...108,247,483
Ensembl chr 1:107,627,390...108,246,763
JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of GABRR3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GABRR3 mRNA
CTD PMID:19564919 NCBI chr11:40,902,812...40,955,263
Ensembl chr11:40,902,812...40,955,263
JBrowse link
G Gad2 glutamate decarboxylase 2 increases expression EXP Methamphetamine results in increased expression of GAD2 mRNA CTD PMID:15601951 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45B mRNA
Methamphetamine results in increased expression of GADD45B mRNA
CTD PMID:19564919 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression
multiple interactions
EXP Methamphetamine results in increased expression of GADD45G mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45G mRNA
CTD PMID:19564919 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression
decreases expression
ISO
EXP
Methamphetamine results in increased expression of GAL mRNA
Methamphetamine results in decreased expression of GAL mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Galk1 galactokinase 1 decreases expression EXP Methamphetamine results in decreased expression of GALK1 mRNA CTD PMID:19564919 NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337
JBrowse link
G Galntl6 polypeptide N-acetylgalactosaminyltransferase-like 6 decreases expression ISO Methamphetamine results in decreased expression of GALNTL6 mRNA CTD PMID:26307267 NCBI chr16:31,192,880...32,443,979
Ensembl chr16:31,186,462...32,441,960
JBrowse link
G Galt galactose-1-phosphate uridylyltransferase increases expression ISO Methamphetamine results in increased expression of GALT mRNA CTD PMID:26307267 NCBI chr 5:56,927,039...56,930,284
Ensembl chr 5:56,926,724...56,930,265
JBrowse link
G Gap43 growth associated protein 43 multiple interactions
decreases expression
EXP Melatonin inhibits the reaction [Methamphetamine results in decreased expression of GAP43 protein] CTD PMID:19409439 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Garin5a golgi associated RAB2 interactor 5A decreases expression EXP Methamphetamine results in decreased expression of GARIN5A mRNA CTD PMID:19564919 NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539
JBrowse link
G Gas5 growth arrest specific 5 increases expression EXP Methamphetamine results in increased expression of GAS5 mRNA CTD PMID:28619521 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gas8 growth arrest specific 8 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of GAS8 mRNA
Methamphetamine results in decreased expression of GAS8 mRNA
CTD PMID:19564919 NCBI chr19:51,552,770...51,572,323
Ensembl chr19:51,552,816...51,572,305
JBrowse link
G Gata4 GATA binding protein 4 increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of GATA4 mRNA; Methamphetamine results in increased expression of GATA4 protein
GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN1A protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN2A protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of EDN3 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of GDF15 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of GLB1 protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1A mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of TGFB2 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased phosphorylation of RELA protein]
CTD PMID:36914120 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gatad2b GATA zinc finger domain containing 2B increases expression EXP Methamphetamine results in increased expression of GATAD2B mRNA CTD PMID:19564919 NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542
JBrowse link
G Gbf1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 increases expression ISO Methamphetamine results in increased expression of GBF1 mRNA CTD PMID:26307267 NCBI chr 1:245,018,535...245,147,052
Ensembl chr 1:245,018,568...245,147,042
JBrowse link
G Gbgt1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) increases expression EXP Methamphetamine results in increased expression of GBGT1 mRNA CTD PMID:28341135 NCBI chr 3:11,826,131...11,829,745 JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP Methamphetamine results in increased expression of GCH1 mRNA CTD PMID:19564919 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gcsh glycine cleavage system protein H decreases expression EXP Methamphetamine results in decreased expression of GCSH mRNA CTD PMID:19149911 NCBI chr19:45,036,013...45,046,770
Ensembl chr19:45,036,011...45,046,792
JBrowse link
G Gda guanine deaminase decreases expression EXP Methamphetamine results in decreased expression of GDA protein CTD PMID:19826936 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of GDF15 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA; GATA4 protein affects the reaction [Methamphetamine results in increased expression of GDF15 mRNA]
CTD PMID:19564919 PMID:25290377 PMID:36914120 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdi1 GDP dissociation inhibitor 1 decreases expression EXP Methamphetamine results in decreased expression of GDI1 protein CTD PMID:19826936 NCBI chr  X:152,087,611...152,094,274
Ensembl chr  X:152,087,444...152,094,272
JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases response to substance ISO GDNF protein results in decreased susceptibility to Methamphetamine CTD PMID:17356005 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of GEM mRNA
Methamphetamine results in increased expression of GEM mRNA
CTD PMID:19564919 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
affects expression
ISO
EXP
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [[PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein]; [PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein; isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; Raclopride inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP mRNA]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; TAAR1 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]
Methamphetamine results in increased expression of GFAP mRNA; Methamphetamine results in increased expression of GFAP protein
Methamphetamine affects the expression of GFAP protein
CTD PMID:9427479 PMID:9634552 PMID:9739098 PMID:10773198 PMID:12766323 More... NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gfra2 GDNF family receptor alpha 2 increases expression EXP Methamphetamine results in increased expression of GFRA2 mRNA CTD PMID:15644446 NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
JBrowse link
G Gfra4 GDNF family receptor alpha 4 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of GFRA4 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GFRA4 mRNA
CTD PMID:19564919 NCBI chr 3:118,254,937...118,262,252
Ensembl chr 3:118,255,402...118,258,329
JBrowse link
G Gigyf1 GRB10 interacting GYF protein 1 increases methylation
increases expression
ISO Methamphetamine results in increased methylation of GIGYF1 promoter
Methamphetamine results in increased expression of GIGYF1 mRNA
CTD PMID:26307267 NCBI chr12:19,166,070...19,181,570
Ensembl chr12:19,166,088...19,175,023
JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 increases expression ISO Methamphetamine results in increased expression of GIGYF2 mRNA CTD PMID:26307267 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715
JBrowse link
G Gipc3 GIPC PDZ domain containing family, member 3 decreases expression EXP Methamphetamine results in decreased expression of GIPC3 mRNA CTD PMID:19564919 NCBI chr 7:8,374,941...8,383,281 JBrowse link
G Gja4 gap junction protein, alpha 4 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of GJA4 mRNA
Methamphetamine results in decreased expression of GJA4 mRNA
CTD PMID:19564919 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression EXP Methamphetamine results in increased expression of GJA5 mRNA CTD PMID:15644446 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions
increases expression
EXP GATA4 protein affects the reaction [Methamphetamine results in increased expression of GLB1 protein] CTD PMID:36914120 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Gli1 GLI family zinc finger 1 decreases expression EXP Methamphetamine results in decreased expression of GLI1 mRNA CTD PMID:19564919 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Glo1 glyoxalase 1 increases expression EXP Methamphetamine results in increased expression of GLO1 protein CTD PMID:19826936 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gls glutaminase multiple interactions
decreases expression
EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA] CTD PMID:19149911 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Glyctk glycerate kinase increases methylation ISO Methamphetamine results in increased methylation of GLYCTK promoter CTD PMID:26307267 NCBI chr 8:106,795,461...106,802,675
Ensembl chr 8:106,797,343...106,802,397
JBrowse link
G Gm2a ganglioside GM2 activator decreases expression EXP Methamphetamine results in decreased expression of GM2A mRNA CTD PMID:19564919 NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757
JBrowse link
G Gmfb glia maturation factor, beta affects expression EXP Methamphetamine affects the expression of GMFB protein CTD PMID:17904249 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
JBrowse link
G Gnb1 G protein subunit beta 1 decreases expression EXP Methamphetamine results in decreased expression of GNB1 protein CTD PMID:19826936 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124
JBrowse link
G Gnb2 G protein subunit beta 2 decreases expression EXP Methamphetamine results in decreased expression of GNB2 protein CTD PMID:19826936 NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
JBrowse link
G Gnb3 G protein subunit beta 3 decreases expression EXP Methamphetamine results in decreased expression of GNB3 protein CTD PMID:19826936 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
JBrowse link
G Golgb1 golgin B1 increases expression ISO Methamphetamine results in increased expression of GOLGB1 mRNA CTD PMID:26307267 NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770
JBrowse link
G Golph3 golgi phosphoprotein 3 increases expression EXP Methamphetamine results in increased expression of GOLPH3 mRNA CTD PMID:19564919 NCBI chr 2:61,348,030...61,376,051
Ensembl chr 2:61,348,030...61,376,049
JBrowse link
G Gon4l gon-4 like increases expression ISO Methamphetamine results in increased expression of GON4L mRNA CTD PMID:26307267 NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions
decreases expression
EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GOT2 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GOT2 mRNA] CTD PMID:19149911 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Methamphetamine results in increased expression of GPNMB mRNA CTD PMID:25290377 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr150 G protein-coupled receptor 150 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of GPR150 mRNA
Methamphetamine results in decreased expression of GPR150 mRNA
CTD PMID:19564919 NCBI chr 2:5,546,304...5,550,889
Ensembl chr 2:5,548,578...5,550,714
JBrowse link
G Gpr17 G protein-coupled receptor 17 decreases expression EXP Methamphetamine results in decreased expression of GPR17 mRNA CTD PMID:28619521 NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966
JBrowse link
G Gpr19 G protein-coupled receptor 19 increases expression EXP Methamphetamine results in increased expression of GPR19 mRNA CTD PMID:19564919 NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036
JBrowse link
G Gpr4 G protein-coupled receptor 4 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of GPR4 mRNA
Methamphetamine results in increased expression of GPR4 mRNA
CTD PMID:19564919 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599
JBrowse link
G Gpr65 G-protein coupled receptor 65 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of GPR65 mRNA
Methamphetamine results in increased expression of GPR65 mRNA
CTD PMID:19564919 NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512
JBrowse link
G Gpsm1 G-protein signaling modulator 1 increases expression ISO Methamphetamine results in increased expression of GPSM1 mRNA CTD PMID:26307267 NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
decreases expression
EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GPT mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GPT mRNA] CTD PMID:19149911 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 affects response to substance
multiple interactions
ISO GPX1 protein affects the susceptibility to Methamphetamine
GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; GPX1 protein affects the reaction [Methamphetamine results in increased activity of RELA protein]; Methamphetamine affects the expression of and affects the activity of GPX1 protein; pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]]
CTD PMID:34082047 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grb2 growth factor receptor bound protein 2 affects expression EXP Methamphetamine affects the expression of GRB2 protein CTD PMID:17904249 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 affects expression EXP Methamphetamine affects the expression of GRIA1 mRNA CTD PMID:18419818 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of GRIA2 mRNA; Methamphetamine results in increased expression of GRIA2 protein
3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine inhibits the reaction [Methamphetamine results in increased expression of GRIA2 protein]
CTD PMID:18419818 PMID:23711322 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP Methamphetamine results in increased expression of GRIA3 mRNA CTD PMID:18419818 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 increases expression EXP Methamphetamine results in increased expression of GRIN1 mRNA CTD PMID:18419818 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A increases expression EXP Methamphetamine results in increased expression of GRIN2A mRNA CTD PMID:18419818 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression
decreases expression
ISO
EXP
Methamphetamine results in increased expression of GRIN2B protein
Methamphetamine results in decreased expression of GRIN2B mRNA
Methamphetamine results in increased expression of GRIN2B mRNA
CTD PMID:17105907 PMID:18419818 PMID:32035215 PMID:32203791 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases expression ISO Methamphetamine results in decreased expression of GRIN2D mRNA CTD PMID:21886566 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression ISO Methamphetamine results in increased expression of GRINA mRNA CTD PMID:26307267 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Grip2 glutamate receptor interacting protein 2 increases expression ISO Methamphetamine results in increased expression of GRIP2 mRNA CTD PMID:26307267 NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268
JBrowse link
G Gripap1 GRIP1 associated protein 1 increases expression ISO Methamphetamine results in increased expression of GRIPAP1 mRNA CTD PMID:26307267 NCBI chr  X:14,678,896...14,708,747
Ensembl chr  X:14,678,898...14,708,679
JBrowse link
G Grm1 glutamate metabotropic receptor 1 increases expression EXP Methamphetamine results in increased expression of GRM1 mRNA CTD PMID:18419818 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases response to substance
multiple interactions
ISO GRM2 gene SNP results in increased susceptibility to Methamphetamine
[Piperidines results in increased activity of GRM2 protein] which results in decreased susceptibility to Methamphetamine
CTD PMID:20211215 PMID:21366332 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Grm3 glutamate metabotropic receptor 3 decreases expression
increases expression
EXP Methamphetamine results in decreased expression of GRM3 mRNA
Methamphetamine results in increased expression of GRM3 mRNA
CTD PMID:15644446 PMID:18419818 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
JBrowse link
G Grm5 glutamate metabotropic receptor 5 multiple interactions
increases expression
EXP [6-methyl-2-(phenylethynyl)pyridine binds to and results in decreased activity of GRM5 protein] inhibits the reaction [Methamphetamine results in decreased abundance of Dopamine]; [6-methyl-2-(phenylethynyl)pyridine binds to and results in decreased activity of GRM5 protein] inhibits the reaction [Methamphetamine results in increased secretion of Dopamine]
Methamphetamine results in increased expression of GRM5 mRNA; Methamphetamine results in increased expression of GRM5 protein
CTD PMID:12907309 PMID:18419818 PMID:23711322 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha decreases expression
affects phosphorylation
multiple interactions
ISO Methamphetamine results in decreased expression of GSK3A protein
Methamphetamine affects the phosphorylation of GSK3A protein
Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of GSK3A protein]
CTD PMID:16192988 PMID:31270305 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
affects phosphorylation
increases expression
decreases phosphorylation
increases phosphorylation
ISO
EXP
Rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of GSK3B protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GSK3B protein modified form]; TWS 119 inhibits the reaction [Methamphetamine results in increased phosphorylation of GSK3B protein]
Methamphetamine affects the phosphorylation of GSK3B protein
Metformin inhibits the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of GSK3B protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of GSK3B protein
Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of GSK3B protein]
Methamphetamine results in decreased phosphorylation of GSK3B protein
CTD PMID:29981415 PMID:30367931 PMID:30742852 PMID:31270305 PMID:32278788 More... NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
EXP Metformin inhibits the reaction [Methamphetamine results in decreased activity of GSR protein] CTD PMID:30742852 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of GSTA3 mRNA
Lithium inhibits the reaction [Methamphetamine results in decreased expression of GSTA3 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GSTA3 mRNA]
CTD PMID:19149911 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance
decreases response to substance
ISO GSTM1 gene polymorphism affects the susceptibility to Methamphetamine
GSTM1 protein results in decreased susceptibility to Methamphetamine
CTD PMID:15048646 PMID:19254865 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases response to substance ISO GSTP1 exon polymorphism results in increased susceptibility to Methamphetamine CTD PMID:15729709 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects response to substance ISO GSTT1 gene polymorphism affects the susceptibility to Methamphetamine; GSTT1 protein affects the susceptibility to Methamphetamine CTD PMID:18186040 PMID:19254865 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gtpbp10 GTP binding protein 10 decreases expression EXP Methamphetamine results in decreased expression of GTPBP10 mRNA CTD PMID:19564919 NCBI chr 4:28,476,857...28,494,375
Ensembl chr 4:28,476,857...28,494,375
JBrowse link
G Gtsf2 gametocyte specific factor 2 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of GTSF2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GTSF2 mRNA
CTD PMID:19564919 NCBI chr 7:134,565,889...134,572,047
Ensembl chr 7:134,565,889...134,572,047
JBrowse link
G H3f3a H3.3 histone A decreases expression ISO Methamphetamine results in decreased expression of H3F3A mRNA CTD PMID:26307267 NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions
increases expression
ISO NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of HAVCR1 protein]; sulforaphane inhibits the reaction [Methamphetamine results in increased expression of HAVCR1 protein] CTD PMID:37567421 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hba-a3 hemoglobin alpha, adult chain 3 decreases expression EXP Methamphetamine results in decreased expression of HBA-A3 mRNA CTD PMID:32035215 NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 increases expression EXP Methamphetamine results in increased expression of HCN4 mRNA CTD PMID:15644446 NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639
JBrowse link
G Hcrt hypocretin neuropeptide precursor increases methylation
multiple interactions
affects expression
ISO
EXP
Methamphetamine results in increased methylation of HCRT promoter
[Methamphetamine co-treated with SCH 23390] results in decreased expression of HCRT mRNA
Methamphetamine affects the expression of HCRT mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Hdac10 histone deacetylase 10 decreases expression EXP Methamphetamine results in decreased expression of HDAC10 mRNA CTD PMID:25452209 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
JBrowse link
G Hdac11 histone deacetylase 11 decreases expression EXP Methamphetamine results in decreased expression of HDAC11 mRNA CTD PMID:25452209 NCBI chr 4:123,645,873...123,667,407
Ensembl chr 4:123,650,157...123,667,405
JBrowse link
G Hdac6 histone deacetylase 6 decreases expression EXP Methamphetamine results in decreased expression of HDAC6 mRNA CTD PMID:25452209 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Hdac7 histone deacetylase 7 increases expression ISO Methamphetamine results in increased expression of HDAC7 mRNA CTD PMID:26307267 NCBI chr 7:128,923,918...128,961,926
Ensembl chr 7:128,923,920...128,962,072
JBrowse link
G Hdac8 histone deacetylase 8 decreases expression EXP Methamphetamine results in decreased expression of HDAC8 mRNA CTD PMID:25452209 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923
JBrowse link
G Hdac9 histone deacetylase 9 decreases expression EXP Methamphetamine results in decreased expression of HDAC9 mRNA CTD PMID:25452209 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
JBrowse link
G Hdc histidine decarboxylase multiple interactions
affects response to substance
ISO HDC protein affects the reaction [Methamphetamine results in decreased abundance of gamma-Aminobutyric Acid]
HDC protein affects the susceptibility to Methamphetamine
CTD PMID:12421355 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 increases expression ISO Methamphetamine results in increased expression of HERC2 mRNA CTD PMID:26307267 NCBI chr 1:106,904,789...107,110,997
Ensembl chr 1:106,880,084...107,108,134
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of HERPUD1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of HERPUD1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HERPUD1 mRNA]
CTD PMID:19564919 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression EXP Methamphetamine results in increased expression of HES1 mRNA CTD PMID:19564919 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes5 hes family bHLH transcription factor 5 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of HES5 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of HES5 mRNA
CTD PMID:19564919 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
JBrowse link
G Hist1h4b histone cluster 1 H4 family member B increases expression
multiple interactions
EXP Methamphetamine results in increased expression of HIST1H4B mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of HIST1H4B mRNA
CTD PMID:19564919 NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370
JBrowse link
G Hjurp Holliday junction recognition protein decreases expression ISO Methamphetamine results in decreased expression of HJURP mRNA CTD PMID:25290377 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728
JBrowse link
G Hk1 hexokinase 1 increases expression ISO Methamphetamine results in increased expression of HK1 mRNA CTD PMID:26307267 PMID:36914120 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hmbs hydroxymethylbilane synthase decreases expression EXP Methamphetamine results in decreased expression of HMBS mRNA CTD PMID:24042092 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of HMGA1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of HMGA1 mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP
ISO
[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] which results in decreased susceptibility to Methamphetamine; [Methamphetamine co-treated with SCH 23390] results in increased expression of HMOX1 mRNA; [tin protoporphyrin IX results in decreased activity of HMOX1 protein] which results in decreased susceptibility to Methamphetamine; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 mRNA]; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 protein]; Methamphetamine promotes the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 protein]; Methamphetamine results in increased expression of and results in increased activity of HMOX1 protein; SB 203580 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [Methamphetamine results in increased activity of HMOX1 protein]
sulforaphane promotes the reaction [Methamphetamine results in increased expression of HMOX1 protein]
Methamphetamine results in increased expression of HMOX1 mRNA; Methamphetamine results in increased expression of HMOX1 protein
CTD PMID:19564919 PMID:19576919 PMID:23022510 PMID:23933405 PMID:28619521 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Methamphetamine results in increased expression of HOMER1 mRNA; Methamphetamine results in increased expression of HOMER1 mRNA alternative form; Methamphetamine results in increased expression of HOMER1 protein alternative form CTD PMID:15644446 PMID:17630046 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hoxc10 homeo box C10 decreases methylation
decreases expression
ISO Methamphetamine results in decreased methylation of HOXC10 promoter
Methamphetamine results in decreased expression of HOXC10 mRNA
CTD PMID:26307267 NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966
JBrowse link
G Hpca hippocalcin decreases expression EXP Methamphetamine results in decreased expression of HPCA mRNA CTD PMID:15644446 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Hpse heparanase increases methylation ISO Methamphetamine results in increased methylation of HPSE promoter CTD PMID:26307267 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor decreases expression EXP Methamphetamine results in decreased expression of HR mRNA CTD PMID:19564919 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases expression EXP Methamphetamine results in decreased expression of HRAS mRNA CTD PMID:15644446 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hrc histidine rich calcium binding protein multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of HRC mRNA
Methamphetamine results in decreased expression of HRC mRNA
CTD PMID:19564919 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression ISO Methamphetamine results in increased expression of HRK mRNA CTD PMID:25290377 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hs3st4 heparan sulfate-glucosamine 3-sulfotransferase 4 affects response to substance ISO HS3ST4 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 1:178,539,078...178,944,850
Ensembl chr 1:178,539,093...178,944,107
JBrowse link
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone decreases expression EXP Methamphetamine results in decreased expression of HSCB mRNA CTD PMID:19564919 NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909
JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 decreases expression EXP Methamphetamine results in decreased expression of HSD3B7 mRNA CTD PMID:19564919 NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:182,412,151...182,415,442
JBrowse link
G Hsf2bp heat shock transcription factor 2 binding protein multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of HSF2BP mRNA
Methamphetamine results in increased expression of HSF2BP mRNA
CTD PMID:19564919 NCBI chr20:10,035,562...10,123,059
Ensembl chr20:10,035,562...10,121,242
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP
ISO
Methamphetamine results in increased expression of HSP90AA1 mRNA CTD PMID:19564919 PMID:36914120 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa12b heat shock protein family A (Hsp70) member 12B increases expression
decreases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of HSPA12B mRNA
Methamphetamine results in decreased expression of HSPA12B mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of HSPA12B mRNA]
CTD PMID:19564919 PMID:26307267 NCBI chr 3:118,346,372...118,364,374
Ensembl chr 3:118,346,354...118,364,737
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP Methamphetamine results in increased expression of HSPA1A protein CTD PMID:19826936 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 affects expression
multiple interactions
increases expression
EXP
ISO
Methamphetamine affects the expression of HSPA5 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of HSPA5 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of HSPA5 mRNA]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of HSPA5 mRNA]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of HSPA5 protein]
Methamphetamine results in increased expression of HSPA5 mRNA; Methamphetamine results in increased expression of HSPA5 protein
[Methamphetamine co-treated with SCH 23390] results in increased expression of HSPA5 mRNA; Melatonin promotes the reaction [Methamphetamine results in increased expression of HSPA5 mRNA]; Melatonin promotes the reaction [Methamphetamine results in increased expression of HSPA5 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPA5 mRNA]
CTD PMID:19564919 PMID:19826936 PMID:27323860 PMID:28070110 PMID:32203791 More... NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP Methamphetamine results in increased expression of HSPA8 protein CTD PMID:19826936 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions
increases expression
EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of HSPA9 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of HSPA9 mRNA] CTD PMID:19149911 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of HSPB1 mRNA; Methamphetamine results in increased expression of HSPB1 protein
[Methamphetamine co-treated with SCH 23390] results in increased expression of HSPB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPB1 mRNA]
CTD PMID:12684743 PMID:19564919 PMID:26307267 PMID:36914120 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions
increases expression
EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPB8 mRNA] CTD PMID:19564919 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression EXP Methamphetamine results in decreased expression of HSPD1 protein CTD PMID:19826936 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 increases expression ISO Methamphetamine results in increased expression of HSPG2 mRNA CTD PMID:26307267 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases response to substance
multiple interactions
ISO HTR1A gene SNP results in increased susceptibility to Methamphetamine
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Methamphetamine
CTD PMID:15213358 PMID:19747927 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F increases expression EXP Methamphetamine results in increased expression of HTR1F mRNA CTD PMID:19564919 NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions EXP [[volinanserin binds to and results in decreased activity of HTR2A protein] which co-treated with GR 127935] results in decreased susceptibility to Methamphetamine; [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in decreased abundance of Serotonin]; [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in increased secretion of Corticosterone]; [volinanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [SB 206553 results in increased susceptibility to Methamphetamine] CTD PMID:11751031 PMID:19879056 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B decreases expression EXP Methamphetamine results in decreased expression of HTR2B mRNA CTD PMID:15644446 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions
affects response to substance
ISO
EXP
[Mianserin binds to and results in decreased activity of HTR2C protein] which results in decreased susceptibility to Methamphetamine
HTR2C protein affects the susceptibility to Methamphetamine
CTD PMID:11751031 PMID:15213358 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A affects response to substance ISO HTR3A mRNA affects the susceptibility to Methamphetamine CTD PMID:19689456 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 increases response to substance ISO HTR6 gene SNP results in increased susceptibility to Methamphetamine CTD PMID:20705401 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
JBrowse link
G Hycc2 hyccin PI4KA lipid kinase complex subunit 2 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of HYCC2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of HYCC2 mRNA
CTD PMID:19564919 NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
JBrowse link
G Icam2 intercellular adhesion molecule 2 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of ICAM2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ICAM2 mRNA
CTD PMID:19564919 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293
JBrowse link
G Ice1 interactor of little elongation complex ELL subunit 1 increases expression ISO Methamphetamine results in increased expression of ICE1 mRNA CTD PMID:26307267 NCBI chr 1:32,640,372...32,682,669
Ensembl chr 1:32,640,407...32,679,898
JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression ISO Methamphetamine results in decreased expression of ID1 mRNA CTD PMID:25290377 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression EXP Methamphetamine results in decreased expression of ID3 mRNA CTD PMID:28619521 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression EXP Methamphetamine results in decreased expression of IDH3A protein CTD PMID:19826936 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Idnk Idnk, gluconokinase multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of IDNK mRNA
Methamphetamine results in decreased expression of IDNK mRNA
CTD PMID:19564919 NCBI chr17:6,483,575...6,490,780
Ensembl chr17:6,483,576...6,490,905
JBrowse link
G Ier2 immediate early response 2 increases expression EXP Methamphetamine results in increased expression of IER2 mRNA CTD PMID:19564919 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
JBrowse link
G Ifng interferon gamma multiple interactions
decreases response to substance
ISO IFNG protein inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]
IFNG protein results in decreased susceptibility to Methamphetamine
CTD PMID:18282668 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ift70a1 intraflagellar transport 70A1 decreases expression EXP Methamphetamine results in decreased expression of IFT70A1 mRNA CTD PMID:19564919 NCBI chr 3:60,901,896...60,905,350
Ensembl chr 3:60,901,896...60,905,350
JBrowse link
G Ift80 intraflagellar transport 80 decreases expression EXP Methamphetamine results in decreased expression of IFT80 mRNA CTD PMID:19564919 NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions
increases expression
EXP IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of CASP3 protein]; IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of PARP1 protein]
Methamphetamine results in increased expression of IGFBP5 mRNA; Methamphetamine results in increased expression of IGFBP5 protein
CTD PMID:25127757 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il10 interleukin 10 decreases expression
increases secretion
EXP
ISO
Methamphetamine results in decreased expression of IL10 mRNA
Methamphetamine results in increased secretion of IL10 protein
CTD PMID:15644446 PMID:21276779 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il18 interleukin 18 increases expression
multiple interactions
increases secretion
ISO Methamphetamine results in increased expression of IL18 mRNA; Methamphetamine results in increased expression of IL18 protein
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL18 mRNA]
CTD PMID:33359793 PMID:35390362 PMID:35688268 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in increased expression of IL1A mRNA; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1A mRNA] CTD PMID:19564919 PMID:36914120 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP
ISO
GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of IL1B protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; Metformin inhibits the reaction [Methamphetamine results in increased expression of IL1B protein]
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of and results in increased secretion of IL1B protein]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; [SNCA protein co-treated with Methamphetamine] results in increased expression of IL1B protein; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Methamphetamine results in increased expression of IL1B protein]; Methamphetamine results in increased expression of and results in increased secretion of IL1B protein; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of IL1B protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; TICAM1 protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of IL1B protein]
Methamphetamine results in increased expression of IL1B mRNA; Methamphetamine results in increased expression of IL1B protein
Methamphetamine promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD PMID:19945523 PMID:20374443 PMID:30394308 PMID:30450033 PMID:30742852 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases secretion
affects response to substance
ISO
EXP
[SNCA protein co-treated with Methamphetamine] results in increased expression of IL6 protein; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; IL6 protein affects the reaction [Methamphetamine affects the expression of SLC6A4 protein]; IL6 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; Minocycline inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of IL6 protein]; TICAM1 protein promotes the reaction [Methamphetamine results in increased expression of IL6 protein]
Methamphetamine results in increased expression of IL6 mRNA; Methamphetamine results in increased expression of IL6 protein
IL6 protein affects the susceptibility to Methamphetamine
GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; margatoxin inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; margatoxin inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]
CTD PMID:11093760 PMID:20374443 PMID:21276779 PMID:24533129 PMID:30450033 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Impg1 interphotoreceptor matrix proteoglycan 1 decreases expression
multiple interactions
ISO
EXP
Methamphetamine results in decreased expression of IMPG1 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of IMPG1 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr 8:81,243,624...81,389,722
Ensembl chr 8:81,243,624...81,389,722
JBrowse link
G Inf2 inverted formin 2 increases expression ISO Methamphetamine results in increased expression of INF2 mRNA CTD PMID:26307267 NCBI chr 6:131,649,162...131,675,944
Ensembl chr 6:131,649,211...131,675,941
JBrowse link
G Inha inhibin subunit alpha decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of INHA mRNA
Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of INHA mRNA]
CTD PMID:19149911 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 increases expression
increases methylation
ISO Methamphetamine results in increased expression of INPPL1 mRNA
Methamphetamine results in increased methylation of INPPL1 promoter
CTD PMID:26307267 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Insr insulin receptor increases expression
multiple interactions
decreases phosphorylation
ISO Methamphetamine results in increased expression of INSR mRNA
Rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of INSR protein]
CTD PMID:26307267 PMID:31270305 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Ip6k1 inositol hexakisphosphate kinase 1 increases expression ISO Methamphetamine results in increased expression of IP6K1 mRNA CTD PMID:26307267 NCBI chr 8:108,693,068...108,737,278 JBrowse link
G Iqcf1 IQ motif containing F1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of IQCF1 mRNA
Methamphetamine results in increased expression of IQCF1 mRNA
CTD PMID:19564919 NCBI chr 8:107,129,462...107,133,242
Ensembl chr 8:107,130,704...107,133,249
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression EXP Methamphetamine results in increased expression of IRAK2 mRNA CTD PMID:19564919 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
decreases phosphorylation
increases phosphorylation
ISO rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of IRS1 protein]
Rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of IRS1 protein]
CTD PMID:29981415 PMID:31270305 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 increases expression ISO Methamphetamine results in increased expression of ISG20 mRNA CTD PMID:25290377 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
JBrowse link
G Ist1 IST1 factor associated with ESCRT-III increases expression ISO Methamphetamine results in increased expression of IST1 mRNA CTD PMID:26307267 NCBI chr19:37,648,840...37,671,019
Ensembl chr19:37,648,095...37,670,956
JBrowse link
G Itga1 integrin subunit alpha 1 increases methylation ISO Methamphetamine results in increased methylation of ITGA1 promoter CTD PMID:26307267 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO Methamphetamine results in increased expression of ITGAM protein CTD PMID:32768653 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgav integrin subunit alpha V multiple interactions EXP [Methamphetamine co-treated with Thyroxine] results in increased expression of ITGAV protein CTD PMID:35301009 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itm2a integral membrane protein 2A decreases expression
increases expression
EXP Methamphetamine results in decreased expression of ITM2A mRNA
Methamphetamine results in increased expression of ITM2A mRNA
CTD PMID:19564919 PMID:32035215 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:72,486,381...72,492,363
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 increases expression ISO Methamphetamine results in increased expression of ITPR2 mRNA CTD PMID:26307267 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Itprid2 ITPR interacting domain containing 2 increases expression ISO Methamphetamine results in increased expression of ITPRID2 mRNA CTD PMID:26307267 NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase decreases expression EXP Methamphetamine results in decreased expression of IVD protein CTD PMID:19826936 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
G Ivns1abp influenza virus NS1A binding protein increases expression
decreases methylation
ISO Methamphetamine results in increased expression of IVNS1ABP mRNA
Methamphetamine results in decreased methylation of IVNS1ABP promoter
CTD PMID:26307267 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Jak3 Janus kinase 3 increases expression ISO Methamphetamine results in increased expression of JAK3 mRNA CTD PMID:26307267 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Jaml junction adhesion molecule like multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of JAML mRNA
Methamphetamine results in decreased expression of JAML mRNA
CTD PMID:19564919 NCBI chr 8:45,384,836...45,415,459
Ensembl chr 8:45,383,495...45,416,565
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of JMJD6 promoter
Methamphetamine results in increased expression of JMJD6 mRNA
CTD PMID:26307267 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity
increases expression
affects response to substance
multiple interactions
ISO
EXP
Methamphetamine results in increased activity of JUN protein
Methamphetamine results in increased expression of JUN mRNA
Methamphetamine results in increased expression of JUN protein
JUN protein affects the susceptibility to Methamphetamine
JUN protein affects the reaction [Methamphetamine results in increased activity of CASP3 protein]
CTD PMID:10336889 PMID:11746378 PMID:12391261 PMID:15644446 PMID:19564919 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of JUNB mRNA
Methamphetamine results in decreased expression of JUNB mRNA
Methamphetamine results in increased expression of JUNB mRNA
CTD PMID:15644446 PMID:19564919 PMID:32035215 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kank3 KN motif and ankyrin repeat domains 3 increases expression ISO Methamphetamine results in increased expression of KANK3 mRNA CTD PMID:26307267 NCBI chr 7:14,594,358...14,607,675
Ensembl chr 7:14,594,422...14,607,675
JBrowse link
G Kat2a lysine acetyltransferase 2A decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of KAT2A promoter
Methamphetamine results in increased expression of KAT2A mRNA
CTD PMID:26307267 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166
JBrowse link
G Kat6a lysine acetyltransferase 6A increases expression ISO Methamphetamine results in increased expression of KAT6A mRNA CTD PMID:26307267 NCBI chr16:69,084,914...69,165,923
Ensembl chr16:69,084,914...69,163,606
JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 multiple interactions
increases expression
EXP margatoxin inhibits the reaction [Methamphetamine results in increased expression of KCNA3 mRNA]; margatoxin inhibits the reaction [Methamphetamine results in increased expression of KCNA3 protein]
Methamphetamine results in increased expression of KCNA3 mRNA; Methamphetamine results in increased expression of KCNA3 protein
CTD PMID:24533129 NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of KCNB1 mRNA
Methamphetamine results in increased expression of KCNB1 protein
2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate inhibits the reaction [Methamphetamine results in increased expression of KCNB1 protein]; pyrazolanthrone inhibits the reaction [Methamphetamine results in increased expression of KCNB1 protein]; SB 203580 inhibits the reaction [Methamphetamine results in increased expression of KCNB1 protein]
CTD PMID:26307267 PMID:29297590 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 increases expression EXP Methamphetamine results in increased expression of KCNE1 mRNA CTD PMID:15644446 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 decreases expression EXP Methamphetamine results in decreased expression of KCNIP2 mRNA CTD PMID:35863504 NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
JBrowse link
G Kcnj14 potassium inwardly-rectifying channel, subfamily J, member 14 increases expression EXP Methamphetamine results in increased expression of KCNJ14 mRNA CTD PMID:19564919 NCBI chr 1:96,293,159...96,300,810
Ensembl chr 1:96,293,435...96,495,459
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 decreases expression ISO Methamphetamine results in decreased expression of KCNJ3 mRNA CTD PMID:21886566 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions
decreases expression
ISO Fluoxetine inhibits the reaction [Methamphetamine results in decreased expression of KCNJ4 mRNA] CTD PMID:21886566 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 increases expression EXP Methamphetamine results in increased expression of KCNJ5 mRNA CTD PMID:15644446 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518
JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 decreases expression ISO Methamphetamine results in decreased expression of KCNJ6 mRNA CTD PMID:21886566 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758
JBrowse link
G Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 decreases expression ISO Methamphetamine results in decreased expression of KCNJ9 mRNA CTD PMID:21886566 NCBI chr13:84,780,826...84,787,928
Ensembl chr13:84,779,741...84,787,928
JBrowse link
G Kctd14 potassium channel tetramerization domain containing 14 increases expression EXP Methamphetamine results in increased expression of KCTD14 mRNA CTD PMID:19564919 NCBI chr 1:151,761,688...151,766,693
Ensembl chr 1:151,761,663...151,766,691
JBrowse link
G Kdm6a lysine demethylase 6A increases expression ISO Methamphetamine results in increased expression of KDM6A mRNA CTD PMID:26307267 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Kdm6b lysine demethylase 6B increases expression ISO
EXP
Methamphetamine results in increased expression of KDM6B mRNA CTD PMID:19564919 PMID:26307267 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794
JBrowse link
G Kif15 kinesin family member 15 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of KIF15 mRNA
Methamphetamine results in decreased expression of KIF15 mRNA
CTD PMID:19564919 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
JBrowse link
G Kif17 kinesin family member 17 increases expression ISO Methamphetamine results in increased expression of KIF17 protein CTD PMID:17105907 NCBI chr 5:150,482,288...150,521,471
Ensembl chr 5:150,481,578...150,519,638
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO
EXP
Methamphetamine results in decreased expression of KIF20A mRNA CTD PMID:25290377 PMID:28341135 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kifbp kinesin family binding protein decreases expression ISO Methamphetamine results in decreased expression of KIFBP mRNA CTD PMID:26307267 NCBI chr20:30,512,899...30,532,504
Ensembl chr20:30,512,901...30,532,476
JBrowse link
G Kifc1 kinesin family member C1 decreases expression ISO Methamphetamine results in decreased expression of KIFC1 mRNA CTD PMID:25290377 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
JBrowse link
G Klf10 KLF transcription factor 10 increases expression EXP Methamphetamine results in increased expression of KLF10 mRNA CTD PMID:19564919 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Klf15 KLF transcription factor 15 increases expression
decreases expression
EXP
ISO
Methamphetamine results in increased expression of KLF15 protein
Methamphetamine results in decreased expression of KLF15 mRNA
CTD PMID:35863504 PMID:36914120 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
JBrowse link
G Klf5 KLF transcription factor 5 increases expression EXP Methamphetamine results in increased expression of KLF5 mRNA CTD PMID:19564919 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Klf6 KLF transcription factor 6 increases expression
decreases expression
EXP
ISO
Methamphetamine results in increased expression of KLF6 mRNA
Methamphetamine results in decreased expression of KLF6 mRNA
CTD PMID:19564919 PMID:36914120 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Klf7 KLF transcription factor 7 increases expression ISO Methamphetamine results in increased expression of KLF7 mRNA CTD PMID:26307267 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G Klhdc9 kelch domain containing 9 decreases expression EXP Methamphetamine results in decreased expression of KLHDC9 mRNA CTD PMID:19564919 NCBI chr13:83,790,390...83,794,080
Ensembl chr13:83,790,269...83,793,354
JBrowse link
G Klhl15 kelch-like family member 15 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of KLHL15 mRNA
Methamphetamine results in increased expression of KLHL15 mRNA
CTD PMID:19564919 NCBI chr  X:58,994,726...59,050,207
Ensembl chr  X:58,995,461...59,046,069
JBrowse link
G Klhl21 kelch-like family member 21 increases expression ISO Methamphetamine results in increased expression of KLHL21 mRNA CTD PMID:36914120 NCBI chr 5:162,514,888...162,523,545
Ensembl chr 5:162,514,765...162,523,545
JBrowse link
G Klhl22 kelch-like family member 22 increases expression ISO Methamphetamine results in increased expression of KLHL22 mRNA CTD PMID:26307267 NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770
JBrowse link
G Kmt2e lysine methyltransferase 2E increases expression ISO Methamphetamine results in increased expression of KMT2E mRNA CTD PMID:26307267 NCBI chr 4:11,658,218...11,727,373
Ensembl chr 4:11,658,979...11,727,373
JBrowse link
G Kndc1 kinase non-catalytic C-lobe domain containing 1 increases expression ISO Methamphetamine results in increased expression of KNDC1 mRNA CTD PMID:26307267 NCBI chr 1:194,689,962...194,738,353
Ensembl chr 1:194,690,135...194,738,362
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein decreases expression EXP Methamphetamine results in decreased expression of KNSTRN mRNA CTD PMID:28341135 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715
JBrowse link
G Kntc1 kinetochore associated 1 decreases expression EXP Methamphetamine results in decreased expression of KNTC1 mRNA CTD PMID:19564919 PMID:28341135 NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561
JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression EXP Methamphetamine results in increased expression of KPNA4 mRNA CTD PMID:19564919 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081
JBrowse link
G Krt14 keratin 14 increases expression ISO Methamphetamine results in increased expression of KRT14 mRNA CTD PMID:25290377 NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt7 keratin 7 affects expression
multiple interactions
EXP Methamphetamine affects the expression of KRT7 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of KRT7 mRNA
CTD PMID:19564919 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Krt80 keratin 80 increases expression EXP Methamphetamine results in increased expression of KRT80 mRNA CTD PMID:28341135 NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508
JBrowse link
G Kynu kynureninase decreases expression ISO Methamphetamine results in decreased expression of KYNU mRNA CTD PMID:26307267 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of L3MBTL1 mRNA
Methamphetamine results in decreased expression of L3MBTL1 mRNA
CTD PMID:19564919 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
JBrowse link
G Lactb lactamase, beta increases expression EXP Methamphetamine results in increased expression of LACTB mRNA CTD PMID:19149911 NCBI chr 8:67,571,504...67,587,592
Ensembl chr 8:67,571,500...67,587,539
JBrowse link
G Lamb2 laminin subunit beta 2 increases expression ISO Methamphetamine results in increased expression of LAMB2 mRNA CTD PMID:26307267 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 increases expression ISO
EXP
Methamphetamine results in increased expression of LAMP1 mRNA; Methamphetamine results in increased expression of LAMP1 protein CTD PMID:23933405 PMID:34374793 PMID:35643125 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 affects localization
increases expression
EXP
ISO
Methamphetamine affects the localization of LAMP2 protein
Methamphetamine results in increased expression of LAMP2 mRNA; Methamphetamine results in increased expression of LAMP2 protein
CTD PMID:17105920 PMID:35643125 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 affects response to substance ISO LARGE1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
JBrowse link
G Lcn1 lipocalin 1 decreases expression ISO Methamphetamine results in decreased expression of LCN3 mRNA CTD PMID:26307267 NCBI chr 3:9,532,860...9,537,859
Ensembl chr 3:9,532,915...9,536,577
JBrowse link
G Ldb1 LIM domain binding 1 increases expression ISO Methamphetamine results in increased expression of LDB1 mRNA CTD PMID:26307267 NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013
JBrowse link
G Ldhd lactate dehydrogenase D increases expression ISO Methamphetamine results in increased expression of LDHD mRNA CTD PMID:26307267 NCBI chr19:39,583,529...39,588,397
Ensembl chr19:39,573,621...39,595,575
JBrowse link
G Lgals9 galectin 9 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of LGALS9 mRNA
Methamphetamine results in decreased expression of LGALS9 mRNA
CTD PMID:19564919 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Lgi3 leucine-rich repeat LGI family, member 3 decreases expression EXP Methamphetamine results in decreased expression of LGI3 mRNA CTD PMID:19564919 NCBI chr15:45,605,611...45,612,739
Ensembl chr15:45,605,611...45,612,739
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 increases expression EXP Methamphetamine results in increased expression of LGR4 mRNA CTD PMID:19564919 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899
JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 increases expression
decreases methylation
ISO Methamphetamine results in increased expression of LIME1 mRNA
Methamphetamine results in decreased methylation of LIME1 promoter
CTD PMID:26307267 NCBI chr 3:168,490,535...168,496,627
Ensembl chr 3:168,490,074...168,493,127
JBrowse link
G Lims2 LIM zinc finger domain containing 2 increases expression ISO Methamphetamine results in increased expression of LIMS2 mRNA CTD PMID:26307267 NCBI chr18:23,553,937...23,592,137
Ensembl chr18:23,553,937...23,592,137
JBrowse link
G Lin54 lin-54 DREAM MuvB core complex component decreases expression ISO Methamphetamine results in decreased expression of LIN54 mRNA CTD PMID:26307267 NCBI chr14:9,129,775...9,188,244
Ensembl chr14:9,130,336...9,187,790
JBrowse link
G Lingo2 leucine rich repeat and Ig domain containing 2 affects response to substance ISO LINGO2 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 5:50,370,744...51,687,252
Ensembl chr 5:50,367,101...50,516,956
JBrowse link
G Lipe lipase E, hormone sensitive type increases expression EXP Methamphetamine results in increased expression of LIPE mRNA CTD PMID:35863504 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G Llph LLP homolog, long-term synaptic facilitation factor increases methylation ISO Methamphetamine results in increased methylation of LLPH promoter CTD PMID:26307267 NCBI chr 7:55,735,317...55,740,341
Ensembl chr 7:55,735,400...55,740,339
JBrowse link
G Lmf2 lipase maturation factor 2 increases expression ISO Methamphetamine results in increased expression of LMF2 mRNA CTD PMID:26307267 NCBI chr 7:120,418,343...120,422,825
Ensembl chr 7:120,418,345...120,422,823
JBrowse link
G Lmo7 LIM domain 7 increases expression ISO Methamphetamine results in increased expression of LMO7 mRNA CTD PMID:26307267 NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783
JBrowse link
G Lmtk3 lemur tyrosine kinase 3 decreases expression ISO Methamphetamine results in decreased expression of LMTK3 mRNA CTD PMID:26307267 NCBI chr 1:96,261,058...96,280,362
Ensembl chr 1:96,260,977...96,280,672
JBrowse link
G Lpxn leupaxin decreases expression EXP Methamphetamine results in decreased expression of LPXN mRNA CTD PMID:19564919 NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084
JBrowse link
G Lratd1 LRAT domain containing 1 affects expression EXP Methamphetamine affects the expression of LRATD1 mRNA CTD PMID:19564919 NCBI chr 6:36,916,969...36,922,143
Ensembl chr 6:36,913,469...36,922,319
JBrowse link
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 increases expression EXP Methamphetamine results in increased expression of LRIG3 mRNA CTD PMID:19564919 NCBI chr 7:61,816,313...61,866,275
Ensembl chr 7:61,816,342...61,866,481
JBrowse link
G Lrp1 LDL receptor related protein 1 increases expression ISO Methamphetamine results in increased expression of LRP1 mRNA CTD PMID:26307267 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lrrc28 leucine rich repeat containing 28 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of LRRC28 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LRRC28 mRNA
CTD PMID:19564919 NCBI chr 1:121,116,833...121,245,805
Ensembl chr 1:121,127,733...121,245,784
JBrowse link
G Lrrc8c leucine rich repeat containing 8 VRAC subunit C increases expression EXP Methamphetamine results in increased expression of LRRC8C mRNA CTD PMID:19564919 NCBI chr14:4,223,901...4,315,590
Ensembl chr14:4,227,832...4,315,249
JBrowse link
G Lrrfip1 LRR binding FLII interacting protein 1 increases expression ISO Methamphetamine results in increased expression of LRRFIP1 mRNA CTD PMID:26307267 NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250
JBrowse link
G Lsp1 lymphocyte-specific protein 1 decreases methylation ISO Methamphetamine results in decreased methylation of LSP1 promoter CTD PMID:26307267 NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of LTBP1 mRNA
Methamphetamine results in decreased expression of LTBP1 mRNA
CTD PMID:19564919 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 increases expression ISO Methamphetamine results in increased expression of LTBP4 mRNA CTD PMID:26307267 NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178
JBrowse link
G Ltc4s leukotriene C4 synthase decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of LTC4S mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LTC4S mRNA
CTD PMID:19564919 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
JBrowse link
G Ltk leukocyte receptor tyrosine kinase decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of LTK mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LTK mRNA
CTD PMID:19564919 NCBI chr 3:106,734,675...106,741,552
Ensembl chr 3:106,734,676...106,743,369
JBrowse link
G Luc7l2 LUC7-like 2 pre-mRNA splicing factor increases expression ISO Methamphetamine results in increased expression of LUC7L2 mRNA CTD PMID:26307267 NCBI chr 4:67,287,593...67,347,986
Ensembl chr 4:67,287,640...67,347,964
JBrowse link
G Lum lumican decreases expression ISO Methamphetamine results in decreased expression of LUM mRNA CTD PMID:36914120 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Lurap1 leucine rich adaptor protein 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of LURAP1 mRNA
Methamphetamine results in decreased expression of LURAP1 mRNA
CTD PMID:19564919 NCBI chr 5:129,618,926...129,628,651
Ensembl chr 5:129,614,137...129,628,766
JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO Methamphetamine results in increased expression of LY96 mRNA CTD PMID:25290377 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 decreases expression EXP Methamphetamine results in decreased expression of LYPD1 mRNA CTD PMID:28619521 NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493
JBrowse link
G Lyrm9 LYR motif containing 9 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of LYRM9 mRNA
Methamphetamine results in decreased expression of LYRM9 mRNA
CTD PMID:19564919 NCBI chr10:63,725,718...63,739,772
Ensembl chr10:63,725,743...63,739,772
JBrowse link
G Lzic leucine zipper and CTNNBIP1 domain containing increases expression EXP Methamphetamine results in increased expression of LZIC protein CTD PMID:19826936 NCBI chr 5:159,928,260...159,941,512
Ensembl chr 5:159,920,439...159,939,685
JBrowse link
G Lzts2 leucine zipper tumor suppressor 2 increases expression ISO Methamphetamine results in increased expression of LZTS2 mRNA CTD PMID:26307267 NCBI chr 1:243,876,665...243,888,489
Ensembl chr 1:243,880,022...243,888,423
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 increases expression ISO Methamphetamine results in increased expression of MACF1 mRNA CTD PMID:26307267 NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905
JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of MAFF mRNA
Methamphetamine results in increased expression of MAFF mRNA
CTD PMID:19564919 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafk MAF bZIP transcription factor K increases expression EXP Methamphetamine results in increased expression of MAFK mRNA CTD PMID:19564919 NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048
JBrowse link
G Mageb3 MAGE family member B3 increases expression EXP Methamphetamine results in increased expression of MAGEB3 mRNA CTD PMID:28341135 NCBI chr  X:50,865,484...50,866,479
Ensembl chr  X:50,865,484...50,866,479
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 increases expression ISO Methamphetamine results in increased expression of MAGI1 mRNA CTD PMID:26307267 NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of MANF mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of MANF mRNA]
CTD PMID:19564919 PMID:36914120 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Maoa monoamine oxidase A increases expression
multiple interactions
affects response to substance
EXP
ISO
Methamphetamine results in increased expression of MAOA mRNA
Methamphetamine results in increased expression of MAOA protein
[Clorgyline results in decreased activity of MAOA protein] which results in increased susceptibility to Methamphetamine
MAOA protein affects the susceptibility to Methamphetamine
CTD PMID:1905457 PMID:19149911 PMID:32035215 PMID:33359793 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B affects response to substance
multiple interactions
ISO MAOB protein affects the susceptibility to Methamphetamine
[Selegiline results in decreased activity of MAOB protein] which results in increased susceptibility to Methamphetamine
CTD PMID:1905457 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map1a microtubule-associated protein 1A increases expression EXP Methamphetamine results in increased expression of MAP1A protein CTD PMID:19826936 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression
EXP
ISO
Methamphetamine results in increased lipidation of and affects the localization of MAP1LC3B protein; STX17 protein inhibits the reaction [Methamphetamine results in increased lipidation of MAP1LC3B protein]
NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of MAP1LC3B protein]; sulforaphane inhibits the reaction [Methamphetamine results in increased expression of MAP1LC3B protein]
Methamphetamine results in increased expression of MAP1LC3B mRNA
CTD PMID:34374793 PMID:37567421 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP Methamphetamine results in decreased expression of MAP2 mRNA; Methamphetamine results in decreased expression of MAP2 protein CTD PMID:17407499 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression
decreases expression
EXP
ISO
Methamphetamine results in increased expression of MAP2K1 protein
Methamphetamine results in decreased expression of MAP2K1 protein
CTD PMID:16192988 PMID:19826936 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression EXP Methamphetamine results in increased expression of MAP2K3 mRNA CTD PMID:19564919 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 affects response to substance ISO MAP2K5 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 decreases expression ISO Methamphetamine results in decreased expression of MAP2K7 protein CTD PMID:16192988 NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 increases expression EXP Methamphetamine results in increased expression of MAP3K7 mRNA CTD PMID:19564919 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Map4 microtubule-associated protein 4 increases expression ISO Methamphetamine results in increased expression of MAP4 mRNA CTD PMID:26307267 NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362
JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 increases expression ISO Methamphetamine results in increased expression of MAP4K2 mRNA CTD PMID:26307267 NCBI chr 1:203,645,098...203,660,782
Ensembl chr 1:203,645,153...203,660,331
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases expression
decreases phosphorylation
multiple interactions
affects phosphorylation
increases expression
ISO
EXP
Methamphetamine results in decreased expression of MAPK1 protein
Methamphetamine results in decreased phosphorylation of MAPK1 protein
Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of MAPK1 protein]
Methamphetamine results in increased expression of MAPK1 mRNA
CTD PMID:16192988 PMID:19149911 PMID:31270305 PMID:32768653 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression ISO Methamphetamine results in increased expression of MAPK11 mRNA CTD PMID:26307267 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
affects phosphorylation
ISO Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of MAPK3 protein]
Methamphetamine results in decreased phosphorylation of MAPK3 protein
CTD PMID:31270305 PMID:32768653 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Methamphetamine results in increased phosphorylation of MAPK8 protein CTD PMID:32768653 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 increases expression ISO Methamphetamine results in increased expression of MAPK8IP3 mRNA CTD PMID:26307267 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO Methamphetamine results in increased phosphorylation of MAPK9 protein CTD PMID:32768653 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
increases phosphorylation
increases expression
decreases expression
ISO
EXP
(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of MAPT mRNA]; MAPT protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein; Rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MAPT protein modified form]; SNCA protein affects the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein]; TWS 119 inhibits the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]
CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein; Rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein]
Methamphetamine results in increased expression of MAPT mRNA; Methamphetamine results in increased expression of MAPT protein modified form
CTD PMID:11756511 PMID:26307267 PMID:29705343 PMID:29981415 PMID:31270305 More... NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Marveld1 MARVEL domain containing 1 decreases expression EXP Methamphetamine results in decreased expression of MARVELD1 mRNA CTD PMID:19564919 NCBI chr 1:240,954,050...240,958,101
Ensembl chr 1:240,954,452...240,958,384
JBrowse link
G Mast2 microtubule associated serine/threonine kinase 2 increases expression ISO Methamphetamine results in increased expression of MAST2 mRNA CTD PMID:26307267 NCBI chr 5:129,776,293...129,915,502
Ensembl chr 5:129,775,676...129,915,606
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of MASTL mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of MASTL mRNA
CTD PMID:19564919 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
JBrowse link
G Mau2 MAU2 sister chromatid cohesion factor increases expression ISO Methamphetamine results in increased expression of MAU2 mRNA CTD PMID:26307267 NCBI chr16:19,383,847...19,414,996
Ensembl chr16:19,383,492...19,408,727
JBrowse link
G Mavs mitochondrial antiviral signaling protein increases expression ISO Methamphetamine results in increased expression of MAVS mRNA CTD PMID:36914120 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Mbp myelin basic protein affects expression
multiple interactions
decreases expression
EXP
ISO
Methamphetamine affects the expression of MBP protein
SNCA protein affects the reaction [Methamphetamine results in decreased expression of MBP protein]
CTD PMID:16842764 PMID:17262233 PMID:34562559 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mc4r melanocortin 4 receptor multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of MC4R mRNA
Methamphetamine results in increased expression of MC4R mRNA
CTD PMID:19564919 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mcam melanoma cell adhesion molecule decreases expression EXP Methamphetamine results in decreased expression of MCAM mRNA CTD PMID:19564919 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
JBrowse link
G Mcc MCC regulator of WNT signaling pathway increases expression EXP Methamphetamine results in increased expression of MCC mRNA CTD PMID:28341135 NCBI chr18:36,794,206...37,266,237
Ensembl chr18:36,798,372...37,266,819
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression EXP Methamphetamine results in increased expression of MCL1 mRNA CTD PMID:19564919 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor decreases expression ISO Methamphetamine results in decreased expression of MCM10 mRNA CTD PMID:25290377 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364
JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of MCM8 mRNA
Methamphetamine results in decreased expression of MCM8 mRNA
CTD PMID:19564919 NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008
JBrowse link
G Mcoln3 mucolipin TRP cation channel 3 increases expression EXP Methamphetamine results in increased expression of MCOLN3 mRNA CTD PMID:28619521 NCBI chr 2:235,008,716...235,042,885
Ensembl chr 2:234,966,010...235,043,047
JBrowse link
G Med29 mediator complex subunit 29 decreases expression EXP Methamphetamine results in decreased expression of MED29 mRNA CTD PMID:19564919 NCBI chr 1:83,677,961...83,683,365
Ensembl chr 1:83,677,961...83,683,365
JBrowse link
G Meltf melanotransferrin decreases expression EXP Methamphetamine results in decreased expression of MELTF mRNA CTD PMID:19564919 NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300
JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator increases expression ISO Methamphetamine results in increased expression of METRNL mRNA CTD PMID:36914120 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
JBrowse link
G Mettl8 methyltransferase 8, tRNA N3-cytidine decreases expression ISO Methamphetamine results in decreased expression of METTL8 mRNA CTD PMID:26307267 NCBI chr 3:55,731,453...55,863,652
Ensembl chr 3:55,770,167...55,863,676
JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression ISO Methamphetamine results in decreased expression of MFAP4 mRNA CTD PMID:36914120 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155
JBrowse link
G Mfsd10 major facilitator superfamily domain containing 10 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of MFSD10 mRNA
Methamphetamine results in decreased expression of MFSD10 mRNA
CTD PMID:19564919 NCBI chr14:76,103,762...76,107,385
Ensembl chr14:76,103,815...76,107,377
JBrowse link
G Mia2 MIA SH3 domain ER export factor 2 decreases expression ISO Methamphetamine results in decreased expression of MIA2 mRNA CTD PMID:26307267 NCBI chr 6:76,787,508...76,885,246
Ensembl chr 6:76,787,508...76,885,211
JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 increases expression ISO Methamphetamine results in increased expression of MICAL1 mRNA CTD PMID:26307267 NCBI chr20:44,974,137...44,986,089
Ensembl chr20:44,974,138...44,986,089
JBrowse link
G Mical3 microtubule associated monooxygenase, calponin and LIM domain containing 3 increases expression
increases methylation
ISO Methamphetamine results in increased expression of MICAL3 mRNA
Methamphetamine results in increased methylation of MICAL3 promoter
CTD PMID:26307267 NCBI chr 4:154,152,776...154,353,274
Ensembl chr 4:154,153,834...154,302,590
JBrowse link
G Micall1 MICAL-like 1 increases expression ISO Methamphetamine results in increased expression of MICALL1 mRNA CTD PMID:26307267 NCBI chr 7:110,676,706...110,707,171
Ensembl chr 7:110,676,775...110,707,177
JBrowse link
G Mid1ip1 MID1 interacting protein 1 increases expression ISO Methamphetamine results in increased expression of MID1IP1 mRNA CTD PMID:36914120 NCBI chr  X:12,060,993...12,063,318
Ensembl chr  X:12,060,883...12,065,774
JBrowse link
G Mif macrophage migration inhibitory factor decreases expression EXP Methamphetamine results in decreased expression of MIF mRNA CTD PMID:19149911 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Miga2 mitoguardin 2 increases expression ISO Methamphetamine results in increased expression of MIGA2 mRNA CTD PMID:36914120 NCBI chr 3:13,636,235...13,658,895
Ensembl chr 3:13,636,238...13,658,896
JBrowse link
G Mindy2 MINDY lysine 48 deubiquitinase 2 increases expression EXP Methamphetamine results in increased expression of MINDY2 mRNA CTD PMID:19564919 NCBI chr 8:71,268,274...71,327,698
Ensembl chr 8:71,256,447...71,328,453
JBrowse link
G Mir143 microRNA 143 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of MIR143 mRNA
Methamphetamine promotes the reaction [NFKB1 protein binds to MIR143 promoter]; MIR143 mRNA affects the reaction [Methamphetamine results in increased cleavage of CASP1 protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of IL1B protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of NLRP3 protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of NOS2 protein]; NFKB1 protein affects the reaction [Methamphetamine results in decreased expression of MIR143 mRNA]
CTD PMID:30394308 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
JBrowse link
G Mir150 microRNA 150 decreases expression EXP Methamphetamine results in decreased expression of MIR150 mRNA CTD PMID:35863504 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108
JBrowse link
G Mir320a microRNA 320a decreases expression EXP Methamphetamine results in decreased expression of MIR320A mRNA CTD PMID:35863504 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir326 microRNA 326 decreases expression EXP Methamphetamine results in decreased expression of MIR326 mRNA CTD PMID:35863504 NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123
JBrowse link
G Mir331 microRNA 331 decreases expression EXP Methamphetamine results in decreased expression of MIR331 mRNA CTD PMID:35863504 NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485
JBrowse link
G Mir339 microRNA 339 decreases expression EXP Methamphetamine results in decreased expression of MIR339 mRNA CTD PMID:35863504 NCBI chr12:15,277,546...15,277,641
Ensembl chr12:15,277,546...15,277,641
JBrowse link
G Mir423 microRNA 423 decreases expression EXP Methamphetamine results in decreased expression of MIR423 mRNA CTD PMID:35863504 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO
EXP
Methamphetamine results in decreased expression of MKI67 mRNA CTD PMID:25290377 PMID:28619521 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mllt10 MLLT10, histone lysine methyltransferase DOT1L cofactor increases expression ISO Methamphetamine results in increased expression of MLLT10 mRNA CTD PMID:26307267 NCBI chr17:80,821,870...80,949,349
Ensembl chr17:80,822,556...80,949,345
JBrowse link
G Mllt6 MLLT6, PHD finger containing increases expression ISO Methamphetamine results in increased expression of MLLT6 mRNA CTD PMID:26307267 NCBI chr10:82,657,258...82,678,899
Ensembl chr10:82,656,872...82,676,073
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity
decreases expression
increases response to substance
ISO Methamphetamine results in increased activity of MMP2 protein
Methamphetamine results in decreased expression of MMP2 mRNA
MMP2 protein results in increased susceptibility to Methamphetamine
CTD PMID:18198472 PMID:36914120 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases response to substance
increases expression
increases activity
ISO [HIV Envelope Protein gp120 co-treated with Methamphetamine] promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP9 mRNA]; [HIV Envelope Protein gp120 co-treated with Methamphetamine] promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of and results in increased activity of MMP9 protein]; Methamphetamine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP9 mRNA]; Methamphetamine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of MMP9 protein]
MMP9 protein results in increased susceptibility to Methamphetamine
Methamphetamine results in increased expression of MMP9
Methamphetamine results in increased activity of MMP9 protein
CTD PMID:18198472 PMID:18766021 PMID:21425912 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mn1 MN1 proto-oncogene, transcriptional regulator multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of MN1 mRNA
Methamphetamine results in decreased expression of MN1 mRNA
CTD PMID:19564919 NCBI chr12:45,181,794...45,220,959
Ensembl chr12:45,183,085...45,221,651
JBrowse link
G Mov10 Mov10 RNA helicase increases expression ISO Methamphetamine results in increased expression of MOV10 mRNA CTD PMID:26307267 NCBI chr 2:192,292,041...192,315,142
Ensembl chr 2:192,293,470...192,315,083
JBrowse link
G Mpg N-methylpurine-DNA glycosylase multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of MPG mRNA
Methamphetamine results in decreased expression of MPG mRNA
CTD PMID:19564919 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
JBrowse link
G Mppe1 metallophosphoesterase 1 decreases expression EXP Methamphetamine results in decreased expression of MPPE1 mRNA CTD PMID:19564919 NCBI chr18:60,763,418...60,781,553
Ensembl chr18:60,763,419...60,781,553
JBrowse link
G Mprip myosin phosphatase Rho interacting protein increases expression ISO Methamphetamine results in increased expression of MPRIP mRNA CTD PMID:26307267 NCBI chr10:44,453,949...44,573,843
Ensembl chr10:44,453,929...44,569,118
JBrowse link
G Mrm3 mitochondrial rRNA methyltransferase 3 increases expression ISO Methamphetamine results in increased expression of MRM3 mRNA CTD PMID:36914120 NCBI chr10:61,095,920...61,125,421
Ensembl chr10:61,095,952...61,102,630
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 increases expression EXP Methamphetamine results in increased expression of MRPL12 mRNA CTD PMID:19149911 NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913
JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of MRPL18 mRNA] CTD PMID:19149911 NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987
JBrowse link
G Mrpl32 mitochondrial ribosomal protein L32 increases expression EXP Methamphetamine results in increased expression of MRPL32 mRNA CTD PMID:19149911 NCBI chr17:50,565,133...50,568,000
Ensembl chr17:50,565,055...50,568,010
JBrowse link
G Mrpl41 mitochondrial ribosomal protein L41 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of MRPL41 mRNA
Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of MRPL41 mRNA]
CTD PMID:19149911 NCBI chr 3:7,780,658...7,781,576
Ensembl chr 3:7,779,143...7,782,818
JBrowse link
G Mrpl43 mitochondrial ribosomal protein L43 decreases expression EXP Methamphetamine results in decreased expression of MRPL43 mRNA CTD PMID:19149911 NCBI chr 1:243,866,848...243,868,285
Ensembl chr 1:243,866,931...243,868,281
JBrowse link
G Mrpl53 mitochondrial ribosomal protein L53 multiple interactions
increases expression
EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of MRPL53 mRNA] CTD PMID:19149911 NCBI chr 4:115,615,329...115,616,219 JBrowse link
G Msto1 misato mitochondrial distribution and morphology regulator 1 increases expression ISO Methamphetamine results in increased expression of MSTO1 mRNA CTD PMID:26307267 NCBI chr 2:174,305,945...174,310,230
Ensembl chr 2:174,301,861...174,310,216
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression
multiple interactions
ISO Methamphetamine results in increased expression of COX1 mRNA
(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in increased expression of COX1 mRNA]
CTD PMID:11756511 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 multiple interactions
decreases expression
ISO (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of ND2 mRNA] CTD PMID:11756511 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Methamphetamine results in increased expression of MT2A mRNA
Methamphetamine results in increased expression of MT2 mRNA
CTD PMID:20801194 PMID:36914120 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mt3 metallothionein 3 decreases response to substance EXP MT3 protein results in decreased susceptibility to Methamphetamine CTD PMID:20801194 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mta1 metastasis associated 1 increases methylation ISO Methamphetamine results in increased methylation of MTA1 promoter CTD PMID:26307267 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 affects response to substance ISO MTARC1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796
JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 affects response to substance ISO MTARC2 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr13:96,362,810...96,397,284 JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression EXP Methamphetamine results in increased expression of MTHFD2 mRNA CTD PMID:28619521 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mthfsd methenyltetrahydrofolate synthetase domain containing increases expression ISO Methamphetamine results in increased expression of MTHFSD mRNA CTD PMID:26307267 NCBI chr19:49,164,266...49,178,233
Ensembl chr19:49,167,183...49,178,232
JBrowse link
G Mtnr1b melatonin receptor 1B multiple interactions ISO MTNR1B protein promotes the reaction [Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]] CTD PMID:26283214 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases phosphorylation
decreases phosphorylation
ISO
EXP
DDIT4 protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; Methamphetamine inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]
Methamphetamine results in increased phosphorylation of MTOR protein
SNCA protein affects the reaction [Methamphetamine results in increased phosphorylation of MTOR protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased phosphorylation of MTOR protein]
CEBPB protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein promotes the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of MTOR protein; Taurine inhibits the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]
CTD PMID:19054297 PMID:23041169 PMID:26825372 PMID:31059759 PMID:34374793 More... NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mtpn myotrophin affects expression EXP Methamphetamine affects the expression of MTPN protein CTD PMID:17904249 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of MUS81 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of MUS81 mRNA
CTD PMID:19564919 NCBI chr 1:202,790,295...202,796,008
Ensembl chr 1:202,790,466...202,795,843
JBrowse link
G Mutyh mutY DNA glycosylase decreases expression EXP Methamphetamine results in decreased expression of MUTYH mRNA CTD PMID:19564919 NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases methylation ISO Methamphetamine results in increased methylation of MVD promoter CTD PMID:26307267 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Mvk mevalonate kinase increases expression ISO Methamphetamine results in increased expression of MVK mRNA CTD PMID:25290377 NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Mxd4 Max dimerization protein 4 decreases expression ISO Methamphetamine results in decreased expression of MXD4 mRNA CTD PMID:36914120 NCBI chr14:76,562,105...76,576,224
Ensembl chr14:76,561,774...76,576,221
JBrowse link
G Mybpc3 myosin binding protein C3 increases expression ISO Methamphetamine results in increased expression of MYBPC3 mRNA CTD PMID:26307267 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP Methamphetamine results in increased expression of MYC mRNA CTD PMID:19564919 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of MYD88 protein
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]
Methamphetamine results in increased expression of MYD88 mRNA; Methamphetamine results in increased expression of MYD88 protein
Lactulose inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]
CTD PMID:30450033 PMID:33359793 PMID:35390362 PMID:35688268 PMID:36720452 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression ISO
EXP
Methamphetamine results in decreased expression of MYH6 mRNA
Methamphetamine results in decreased expression of MYH6 protein
CTD PMID:23933405 PMID:35863504 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
JBrowse link
G Myh7 myosin heavy chain 7 decreases expression ISO
EXP
Methamphetamine results in decreased expression of MYH7 mRNA
Methamphetamine results in decreased expression of MYH7 protein
CTD PMID:23933405 PMID:35863504 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Mylk myosin light chain kinase affects expression
multiple interactions
increases expression
EXP
ISO
Methamphetamine affects the expression of MYLK mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of MYLK mRNA
Methamphetamine results in increased expression of MYLK mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Myo18a myosin XVIIIa increases expression ISO Methamphetamine results in increased expression of MYO18A mRNA CTD PMID:26307267 NCBI chr10:62,654,218...62,755,465
Ensembl chr10:62,654,281...62,755,468
JBrowse link
G Myo18b myosin XVIIIb increases expression ISO Methamphetamine results in increased expression of MYO18B mRNA CTD PMID:26307267 NCBI chr12:43,747,003...43,953,694
Ensembl chr12:43,747,010...43,953,695
JBrowse link
G Myo5b myosin Vb affects response to substance ISO MYO5B gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr18:68,038,759...68,341,568
Ensembl chr18:68,038,759...68,338,745
JBrowse link
G Myo7a myosin VIIA increases expression ISO Methamphetamine results in increased expression of MYO7A mRNA CTD PMID:26307267 NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
JBrowse link
G Myom1 myomesin 1 increases expression ISO Methamphetamine results in increased expression of MYOM1 mRNA CTD PMID:26307267 NCBI chr 9:110,916,156...111,039,344
Ensembl chr 9:110,915,943...111,039,344
JBrowse link
G Myom2 myomesin 2 increases expression ISO Methamphetamine results in increased expression of MYOM2 mRNA CTD PMID:36914120 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772
JBrowse link
G Myot myotilin increases expression ISO Methamphetamine results in increased expression of MYOT mRNA CTD PMID:36914120 NCBI chr18:36,705,244...36,724,849
Ensembl chr18:36,705,314...36,724,841
JBrowse link
G Mypn myopalladin increases expression ISO Methamphetamine results in increased expression of MYPN mRNA CTD PMID:36914120 NCBI chr20:25,429,898...25,522,443
Ensembl chr20:25,436,843...25,522,443
JBrowse link
G Myt1 myelin transcription factor 1 decreases expression EXP Methamphetamine results in decreased expression of MYT1 mRNA CTD PMID:19564919 NCBI chr 3:168,890,466...168,950,341
Ensembl chr 3:168,886,089...168,950,341
JBrowse link
G N4bp1 Nedd4 binding protein 1 increases expression EXP Methamphetamine results in increased expression of N4BP1 mRNA CTD PMID:19564919 NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570
JBrowse link
G Nab2 Ngfi-A binding protein 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NAB2 mRNA
Methamphetamine results in increased expression of NAB2 mRNA
CTD PMID:19564919 NCBI chr 7:63,497,589...63,504,105
Ensembl chr 7:63,497,589...63,503,989
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression EXP Methamphetamine results in decreased expression of NAMPT mRNA CTD PMID:35863504 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Ncald neurocalcin delta affects expression EXP Methamphetamine affects the expression of NCALD protein CTD PMID:17904249 NCBI chr 7:68,532,671...68,964,740
Ensembl chr 7:68,534,421...68,964,496
JBrowse link
G Ncapg non-SMC condensin I complex, subunit G decreases expression EXP Methamphetamine results in decreased expression of NCAPG mRNA CTD PMID:28341135 NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902
JBrowse link
G Ncbp2as2 NCBP2 antisense 2 (head to head) increases expression ISO Methamphetamine results in increased expression of NCBP2AS2 mRNA CTD PMID:36914120 NCBI chr11:68,829,950...68,830,715
Ensembl chr11:68,829,983...68,830,708
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases phosphorylation
multiple interactions
EXP Methamphetamine results in increased phosphorylation of NCF1 protein
CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; CCK protein modified form inhibits the reaction [Methamphetamine results in increased phosphorylation of NCF1 protein]; Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]
CTD PMID:27565679 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 increases expression ISO Methamphetamine results in increased expression of NCOR2 mRNA CTD PMID:26307267 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression EXP Methamphetamine results in decreased expression of NDC80 mRNA CTD PMID:28341135 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Ndrg3 NDRG family member 3 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of NDRG3 mRNA
(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of NDRG3 mRNA]
CTD PMID:11756511 NCBI chr 3:145,587,505...145,650,896
Ensembl chr 3:145,548,041...145,650,873
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 decreases expression EXP Methamphetamine results in decreased expression of NDST2 mRNA CTD PMID:19564919 NCBI chr15:3,563,515...3,573,801
Ensembl chr15:3,563,358...3,573,801
JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of NDST3 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of NDST3 mRNA
CTD PMID:19564919 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 increases expression EXP Methamphetamine results in increased expression of NDUFA5 mRNA CTD PMID:19149911 NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:52,995,546...53,005,598
JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 increases expression EXP Methamphetamine results in increased expression of NDUFB6 mRNA CTD PMID:19149911 NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 affects expression EXP Methamphetamine affects the expression of NDUFS8 protein CTD PMID:17904249 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 increases expression EXP Methamphetamine results in increased expression of NDUFV2 protein CTD PMID:19826936 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713
JBrowse link
G Necab1 N-terminal EF-hand calcium binding protein 1 increases expression EXP Methamphetamine results in increased expression of NECAB1 mRNA CTD PMID:19564919 NCBI chr 5:28,357,859...28,578,642
Ensembl chr 5:28,357,859...28,578,642
Ensembl chr 5:28,357,859...28,578,642
JBrowse link
G Nefm neurofilament medium chain increases expression EXP Methamphetamine results in increased expression of NEFM mRNA CTD PMID:32035215 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Nek10 NIMA-related kinase 10 decreases expression EXP Methamphetamine results in decreased expression of NEK10 mRNA CTD PMID:32035215 NCBI chr15:10,387,063...10,564,177
Ensembl chr15:10,381,140...10,559,722
JBrowse link
G Neu4 neuraminidase 4 decreases expression ISO Methamphetamine results in decreased expression of NEU4 mRNA CTD PMID:26307267 NCBI chr 9:94,396,920...94,402,576
Ensembl chr 9:94,396,920...94,402,576
JBrowse link
G Neurl2 neuralized E3 ubiquitin protein ligase 2 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of NEURL2 mRNA
Methamphetamine results in decreased expression of NEURL2 mRNA
CTD PMID:19564919 NCBI chr 3:153,566,659...153,569,380
Ensembl chr 3:153,566,660...153,569,380
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO Methamphetamine results in increased expression of NFAT5 mRNA CTD PMID:26307267 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 affects localization
increases expression
multiple interactions
EXP Methamphetamine affects the localization of NFATC3 protein
Methamphetamine results in increased expression of NFATC3 mRNA
SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFATC3 protein]
CTD PMID:15644446 PMID:19564919 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 affects localization
decreases expression
multiple interactions
EXP Methamphetamine affects the localization of NFATC4 protein
Methamphetamine results in decreased expression of NFATC4 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of NFATC4 mRNA; SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFATC4 protein]
CTD PMID:15644446 PMID:19564919 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
affects response to substance
affects localization
EXP
ISO
Methamphetamine results in increased expression of NFE2L2 mRNA
NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of HAVCR1 protein]; NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of MAP1LC3B protein]; sulforaphane promotes the reaction [Methamphetamine results in increased expression of NFE2L2 protein]
NFE2L2 protein affects the susceptibility to Methamphetamine
Lactulose promotes the reaction [Methamphetamine results in increased expression of NFE2L2 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFE2L2 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of NFE2L2 mRNA]
CTD PMID:19564919 PMID:30450033 PMID:37567421 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression
multiple interactions
EXP Methamphetamine results in increased expression of NFIL3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of NFIL3 mRNA
CTD PMID:19564919 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases activity
affects localization
multiple interactions
increases expression
ISO Methamphetamine results in increased activity of NFKB1 protein
Methamphetamine affects the localization of NFKB1 protein
[SNCA protein co-treated with Methamphetamine] results in increased expression of NFKB1 protein; Methamphetamine promotes the reaction [NFKB1 protein binds to MIR143 promoter]; NFKB1 protein affects the reaction [Methamphetamine results in decreased expression of MIR143 mRNA]
Methamphetamine results in increased expression of NFKB1 mRNA; Methamphetamine results in increased expression of NFKB1 protein
CTD PMID:11746378 PMID:26307267 PMID:30394308 PMID:32569805 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
decreases expression
increases phosphorylation
multiple interactions
increases degradation
ISO Methamphetamine results in increased expression of NFKBIA mRNA
Methamphetamine results in decreased expression of NFKBIA mRNA
Methamphetamine results in increased phosphorylation of NFKBIA protein
CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]]
Methamphetamine results in increased degradation of NFKBIA protein
ERN1 protein affects the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; luzindole inhibits the reaction [Melatonin inhibits the reaction [Methamphetamine results in increased degradation of NFKBIA protein]]; Melatonin inhibits the reaction [Methamphetamine results in increased degradation of NFKBIA protein]
CTD PMID:26283214 PMID:26307267 PMID:27323860 PMID:32916201 PMID:36914120 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngf nerve growth factor decreases response to substance
multiple interactions
ISO
EXP
NGF protein results in decreased susceptibility to Methamphetamine
[Methamphetamine co-treated with NGF protein] affects the abundance of Peroxynitrous Acid
CTD PMID:12105096 PMID:15093677 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 multiple interactions
decreases expression
ISO (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of NHERF1 mRNA] CTD PMID:11756511 PMID:26307267 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 increases expression
decreases expression
EXP Methamphetamine results in increased expression of NHERF2 mRNA
Methamphetamine results in decreased expression of NHERF2 mRNA
CTD PMID:19564919 PMID:32035215 NCBI chr10:13,662,461...13,672,975
Ensembl chr10:13,662,461...13,673,049
JBrowse link
G Nhlrc2 NHL repeat containing 2 increases expression EXP Methamphetamine results in increased expression of NHLRC2 mRNA CTD PMID:19564919 NCBI chr 1:255,589,743...255,648,904
Ensembl chr 1:255,589,742...255,651,408
JBrowse link
G Nipal1 NIPA-like domain containing 1 decreases expression ISO Methamphetamine results in decreased expression of NIPAL1 mRNA CTD PMID:26307267 NCBI chr14:35,537,641...35,561,656
Ensembl chr14:35,540,324...35,561,659
JBrowse link
G Nkx2-5 NK2 homeobox 5 increases expression ISO Methamphetamine results in increased expression of NKX2-5 mRNA CTD PMID:36914120 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934
JBrowse link
G Nkx2-6 NK2 homeobox 6 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of NKX2-6 mRNA
Methamphetamine results in decreased expression of NKX2-6 mRNA
CTD PMID:19564919 NCBI chr15:44,443,151...44,447,248
Ensembl chr15:44,443,101...44,447,247
JBrowse link
G Nkx6-2 NK6 homeobox 2 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of NKX6-2 mRNA
Methamphetamine results in decreased expression of NKX6-2 mRNA
CTD PMID:19564919 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
ISO Methamphetamine promotes the reaction [PYCARD protein binds to NLRP3 protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of NLRP3 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased expression of NLRP3 protein] CTD PMID:30394308 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nmu neuromedin U increases expression EXP Methamphetamine results in increased expression of NMU mRNA CTD PMID:19564919 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase increases expression EXP
ISO
Methamphetamine results in increased expression of NNT mRNA CTD PMID:19149911 PMID:36914120 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
JBrowse link
G Noct nocturnin increases expression EXP Methamphetamine results in increased expression of NOCT mRNA CTD PMID:19564919 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
affects response to substance
increases expression
ISO [3-bromo-7-nitroindazole results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; [7-nitroindazole results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; [7-nitroindazole results in decreased activity of NOS1 protein] which results in decreased susceptibility to Methamphetamine; [S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; NOS1 protein affects the reaction [Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein]]; NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of 3,4-Dihydroxyphenylacetic Acid]; NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of Dopamine]; NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of Homovanillic Acid]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; NOS1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein]
NOS1 protein affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of NOS1 protein
CTD PMID:8858965 PMID:9495865 PMID:10642852 PMID:11006970 PMID:11085313 More... NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO BBC3 protein promotes the reaction [Methamphetamine results in increased expression of NOS2 protein]; isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of NOS2 protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of NOS2 protein] CTD PMID:19834288 PMID:30394308 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notum NOTUM, palmitoleoyl-protein carboxylesterase decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of NOTUM mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of NOTUM mRNA
CTD PMID:19564919 NCBI chr10:105,933,245...105,940,327
Ensembl chr10:105,933,249...105,940,315
JBrowse link
G Npas2 neuronal PAS domain protein 2 increases expression EXP Methamphetamine results in increased expression of NPAS2 mRNA CTD PMID:35863504 NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320
JBrowse link
G Npas4 neuronal PAS domain protein 4 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NPAS4 mRNA
Methamphetamine results in increased expression of NPAS4 mRNA
CTD PMID:19564919 NCBI chr 1:202,281,260...202,298,681
Ensembl chr 1:202,281,958...202,286,724
JBrowse link
G Nppb natriuretic peptide B increases expression EXP Methamphetamine results in increased expression of NPPB protein; Methamphetamine results in increased expression of NPPB protein modified form CTD PMID:35863504 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nptx2 neuronal pentraxin 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NPTX2 mRNA
Methamphetamine results in increased expression of NPTX2 mRNA
CTD PMID:19564919 NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345
JBrowse link
G Npy neuropeptide Y increases expression
decreases expression
ISO
EXP
Methamphetamine results in increased expression of NPY mRNA
Methamphetamine results in decreased expression of NPY protein
CTD PMID:15930374 PMID:17910739 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Npy1r neuropeptide Y receptor Y1 increases response to substance
affects expression
ISO NPY1R gene SNP results in increased susceptibility to Methamphetamine
Methamphetamine affects the expression of NPY1R mRNA
CTD PMID:15930374 PMID:19566775 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Npy2r neuropeptide Y receptor Y2 affects expression
increases expression
ISO Methamphetamine affects the expression of NPY2R mRNA
Methamphetamine results in increased expression of NPY2R protein
CTD PMID:15930374 PMID:32956829 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Methamphetamine results in increased expression of NQO1 protein CTD PMID:16403784 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO Methamphetamine results in decreased expression of NR1D1 mRNA CTD PMID:36914120 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of NR1H4 mRNA; Methamphetamine results in increased expression of NR1H4 protein
obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of NR1H4 mRNA]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of NR1H4 protein]
CTD PMID:35688268 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
affects expression
ISO
EXP
[RU 43044 binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Methamphetamine results in increased secretion of Dopamine]; [RU 43044 binds to and results in decreased activity of NR3C1 protein] which results in decreased susceptibility to Methamphetamine
Methamphetamine affects the expression of NR3C1 mRNA
CTD PMID:17254711 PMID:18925659 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression
decreases expression
EXP Methamphetamine results in increased expression of NR4A1 mRNA
Methamphetamine results in decreased expression of NR4A1 mRNA
CTD PMID:15644446 PMID:32035215 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions
decreases expression
increases expression
affects response to substance
ISO
EXP
[SNCA protein co-treated with Methamphetamine] results in decreased expression of NR4A2 protein; NR4A2 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; NR4A2 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]
Methamphetamine results in decreased expression of NR4A2 protein
[Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A2 mRNA
Methamphetamine results in increased expression of NR4A2 mRNA
NR4A2 protein affects the susceptibility to Methamphetamine
CTD PMID:19564919 PMID:21151937 PMID:32569805 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A3 mRNA
Methamphetamine results in increased expression of NR4A3 mRNA
CTD PMID:19564919 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Nradd neurotrophin receptor associated death domain increases expression ISO Methamphetamine results in increased expression of NRADD mRNA CTD PMID:26307267 NCBI chr 8:110,599,667...110,603,068
Ensembl chr 8:110,599,667...110,603,149
JBrowse link
G Nrbp2 nuclear receptor binding protein 2 increases expression ISO Methamphetamine results in increased expression of NRBP2 mRNA CTD PMID:26307267 NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression ISO Methamphetamine results in increased expression of NRF1 mRNA CTD PMID:26307267 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Nrg1 neuregulin 1 affects response to substance ISO NRG1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrm nurim multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of NRM mRNA
Methamphetamine results in decreased expression of NRM mRNA
CTD PMID:19564919 NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802
JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor increases expression ISO Methamphetamine results in increased expression of NSMAF mRNA CTD PMID:26307267 NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627
JBrowse link
G Nsmf NMDA receptor synaptonuclear signaling and neuronal migration factor increases expression ISO Methamphetamine results in increased expression of NSMF mRNA CTD PMID:26307267 NCBI chr 3:7,861,846...7,870,615
Ensembl chr 3:7,861,872...7,870,614
JBrowse link
G Nthl1 nth-like DNA glycosylase 1 decreases expression EXP Methamphetamine results in decreased expression of NTHL1 mRNA CTD PMID:19564919 NCBI chr10:13,655,791...13,661,958
Ensembl chr10:13,655,785...13,661,957
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 decreases expression ISO Methamphetamine results in decreased expression of NTRK2 protein CTD PMID:34461196 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Nts neurotensin increases expression EXP Methamphetamine results in increased expression of NTS mRNA CTD PMID:19564919 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression EXP Methamphetamine results in decreased expression of NUF2 mRNA CTD PMID:28341135 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Nup210l nucleoporin 210-like increases expression
multiple interactions
EXP Methamphetamine results in increased expression of NUP210L mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of NUP210L mRNA
CTD PMID:19564919 NCBI chr 2:175,545,999...175,665,332
Ensembl chr 2:175,547,988...175,665,332
JBrowse link
G Nxph3 neurexophilin 3 increases expression EXP Methamphetamine results in increased expression of NXPH3 mRNA CTD PMID:15644446 NCBI chr10:80,456,283...80,459,949
Ensembl chr10:80,455,429...80,462,415
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO Methamphetamine results in increased expression of OAS2 mRNA CTD PMID:26307267 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
JBrowse link
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF increases expression ISO Methamphetamine results in increased expression of OBSCN mRNA CTD PMID:26307267 NCBI chr10:43,774,113...43,919,718
Ensembl chr10:43,789,293...43,919,723
JBrowse link
G Obsl1 obscurin like cytoskeletal adaptor 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of OBSL1 mRNA
Methamphetamine results in decreased expression of OBSL1 mRNA
CTD PMID:19564919 NCBI chr 9:76,967,802...76,993,771
Ensembl chr 9:76,974,253...76,993,560
JBrowse link
G Ocln occludin multiple interactions
decreases expression
ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of OCLN mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein]; obeticholic acid inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein]
Methamphetamine results in decreased expression of OCLN mRNA; Methamphetamine results in decreased expression of OCLN protein
CTD PMID:35390362 PMID:36720452 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Ogdhl oxoglutarate dehydrogenase L increases expression ISO Methamphetamine results in increased expression of OGDHL mRNA CTD PMID:25290377 PMID:36914120 NCBI chr16:7,578,343...7,604,385
Ensembl chr16:7,578,367...7,604,386
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions
decreases expression
affects response to substance
ISO
EXP
OGG1 protein affects the reaction [Methamphetamine results in increased abundance of 7,8-dihydro-8-oxoguanine]
Methamphetamine results in decreased expression of OGG1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of OGG1 mRNA
OGG1 protein affects the susceptibility to Methamphetamine
CTD PMID:18768699 PMID:19564919 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Olr59 olfactory receptor 59 decreases expression EXP Methamphetamine results in decreased expression of OLR59 mRNA CTD PMID:19564919 NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
JBrowse link
G Oma1 OMA1 zinc metallopeptidase decreases expression EXP Methamphetamine results in decreased expression of OMA1 mRNA CTD PMID:19564919 NCBI chr 5:118,083,728...118,136,980
Ensembl chr 5:118,083,728...118,136,980
JBrowse link
G Onecut1 one cut homeobox 1 decreases expression ISO Methamphetamine results in decreased expression of ONECUT1 mRNA CTD PMID:26307267 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 decreases expression ISO Methamphetamine results in decreased expression of OPRL1 mRNA CTD PMID:21886566 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Oprm1 opioid receptor, mu 1 increases response to substance
decreases expression
multiple interactions
increases expression
ISO
EXP
OPRM1 gene SNP results in increased susceptibility to Methamphetamine
Methamphetamine results in decreased expression of OPRM1 mRNA; Methamphetamine results in decreased expression of OPRM1 protein
Fluoxetine inhibits the reaction [Methamphetamine results in decreased expression of OPRM1 mRNA]; Fluoxetine inhibits the reaction [Methamphetamine results in decreased expression of OPRM1 protein]; OPRM1 protein affects the susceptibility to [Methamphetamine results in decreased expression of TH mRNA]; OPRM1 protein affects the susceptibility to [Methamphetamine results in decreased expression of TH protein]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]]
Methamphetamine results in increased expression of OPRM1 mRNA
[CTAP octapeptide binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Methamphetamine
CTD PMID:15644446 PMID:16402083 PMID:20184921 PMID:20298714 PMID:21886566 More... NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Or14j3d olfactory receptor family 14 subfamily J member 3D decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of OR14J3D mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of OR14J3D mRNA
CTD PMID:19564919 NCBI chr20:872,996...873,910
Ensembl chr20:833,838...846,753
JBrowse link
G Or1o11c olfactory receptor family 1 subfamily O member 11C multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of OR1O11C mRNA
Methamphetamine results in increased expression of OR1O11C mRNA
CTD PMID:19564919 NCBI chr20:1,097,181...1,098,110
Ensembl chr20:1,097,181...1,098,110
JBrowse link
G Or51f1f olfactory receptor family 51 subfamily F member 1F increases expression EXP Methamphetamine results in increased expression of OR51F1F mRNA CTD PMID:28341135 NCBI chr 1:157,479,786...157,484,201
Ensembl chr 1:157,483,242...157,484,201
JBrowse link
G Orc1 origin recognition complex, subunit 1 decreases expression ISO Methamphetamine results in decreased expression of ORC1 mRNA CTD PMID:25290377 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases methylation ISO Methamphetamine results in decreased methylation of OSGIN1 promoter CTD PMID:26307267 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G Ovch2 ovochymase 2 increases expression EXP Methamphetamine results in increased expression of OVCH2 mRNA CTD PMID:28341135 NCBI chr 1:161,693,619...161,713,952
Ensembl chr 1:161,693,647...161,713,952
JBrowse link
G Oxgr1 oxoglutarate receptor 1 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of OXGR1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of OXGR1 mRNA
CTD PMID:19564919 NCBI chr15:97,145,947...97,146,960
Ensembl chr15:97,144,293...97,166,612
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions
affects expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of OXT mRNA
Methamphetamine affects the expression of OXT mRNA
CTD PMID:19564919 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G P2rx4 purinergic receptor P2X 4 decreases expression EXP Methamphetamine results in decreased expression of P2RX4 mRNA CTD PMID:19564919 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
JBrowse link
G P2rx6 purinergic receptor P2X 6 decreases expression EXP Methamphetamine results in decreased expression of P2RX6 mRNA CTD PMID:19564919 NCBI chr11:83,439,922...83,450,449
Ensembl chr11:83,439,924...83,450,481
JBrowse link
G P2ry2 purinergic receptor P2Y2 increases expression ISO Methamphetamine results in increased expression of P2RY2 mRNA CTD PMID:26307267 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of P4HA1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of P4HA1 mRNA
CTD PMID:19564919 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of P4HA2 mRNA
Methamphetamine results in increased expression of P4HA2 mRNA
CTD PMID:19564919 NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314
JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 decreases expression EXP Methamphetamine results in decreased expression of PACSIN1 protein CTD PMID:19826936 NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,719,857...5,765,313
JBrowse link
G Padi6 peptidyl arginine deiminase 6 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PADI6 mRNA
Methamphetamine results in decreased expression of PADI6 mRNA
CTD PMID:19564919 NCBI chr 5:153,021,855...153,037,443
Ensembl chr 5:153,021,965...153,037,414
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 increases expression EXP Methamphetamine results in increased expression of PAIP1 mRNA CTD PMID:28341135 NCBI chr 2:51,523,190...51,550,241
Ensembl chr 2:51,522,921...51,550,241
JBrowse link
G Pak6 p21 (RAC1) activated kinase 6 decreases expression EXP Methamphetamine results in decreased expression of PAK6 mRNA CTD PMID:35863504 NCBI chr 3:105,638,248...105,674,399
Ensembl chr 3:105,638,653...105,672,975
JBrowse link
G Palld palladin, cytoskeletal associated protein increases expression ISO Methamphetamine results in increased expression of PALLD mRNA CTD PMID:26307267 NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
JBrowse link
G Pard3 par-3 family cell polarity regulator increases expression ISO Methamphetamine results in increased expression of PARD3 mRNA CTD PMID:26307267 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778
JBrowse link
G Pard6g par-6 family cell polarity regulator gamma affects expression
multiple interactions
EXP Methamphetamine affects the expression of PARD6G mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of PARD6G mRNA
CTD PMID:19564919 NCBI chr18:73,497,992...73,565,048
Ensembl chr18:73,498,021...73,565,029
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases activity
increases cleavage
increases expression
decreases cleavage
multiple interactions
EXP
ISO
Methamphetamine results in increased activity of PARP1 protein
Methamphetamine results in increased cleavage of PARP1 protein
Methamphetamine results in increased expression of PARP1 protein modified form
Methamphetamine results in decreased cleavage of PARP1 protein
3-methyladenine promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; Chloroquine promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of PARP1 protein modified form]; IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of PARP1 protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of PARP1 protein modified form]; Sirolimus inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; wedelolactone inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]
BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]
CTD PMID:25127757 PMID:25523949 PMID:25631491 PMID:26524635 PMID:26825372 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Parp8 poly (ADP-ribose) polymerase family, member 8 increases expression ISO Methamphetamine results in increased expression of PARP8 mRNA CTD PMID:26307267 NCBI chr 2:48,679,405...48,848,700
Ensembl chr 2:48,679,436...48,849,253
JBrowse link
G Pawr pro-apoptotic WT1 regulator increases expression EXP Methamphetamine results in increased expression of PAWR mRNA CTD PMID:19564919 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pbk PDZ binding kinase decreases expression ISO
EXP
Methamphetamine results in decreased expression of PBK mRNA CTD PMID:25290377 PMID:28341135 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pbxip1 PBX homeobox interacting protein 1 increases expression ISO Methamphetamine results in increased expression of PBXIP1 mRNA CTD PMID:26307267 NCBI chr 2:174,856,339...174,868,922
Ensembl chr 2:174,856,397...174,868,919
JBrowse link
G Pcbp4 poly(rC) binding protein 4 increases expression ISO Methamphetamine results in increased expression of PCBP4 mRNA CTD PMID:26307267 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276
JBrowse link
G Pcdh1 protocadherin 1 increases expression ISO Methamphetamine results in increased expression of PCDH1 mRNA CTD PMID:26307267 NCBI chr18:30,011,692...30,039,679
Ensembl chr18:30,013,185...30,039,318
JBrowse link
G Pcgf6 polycomb group ring finger 6 decreases expression EXP Methamphetamine results in decreased expression of PCGF6 mRNA CTD PMID:19564919 NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression
multiple interactions
ISO
EXP
Methamphetamine results in decreased expression of PCLAF mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PCLAF mRNA
CTD PMID:19564919 PMID:25290377 NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression EXP Methamphetamine results in decreased expression of PCMT1 protein CTD PMID:19826936 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
JBrowse link
G Pcnt pericentrin increases expression ISO Methamphetamine results in increased expression of PCNT mRNA CTD PMID:26307267 NCBI chr20:12,190,597...12,278,723
Ensembl chr20:12,191,648...12,278,710
JBrowse link
G Pcnx3 pecanex 3 increases expression ISO Methamphetamine results in increased expression of PCNX3 mRNA CTD PMID:26307267 NCBI chr 1:202,951,322...202,974,167
Ensembl chr 1:202,951,322...202,976,561
JBrowse link
G PCOLCE2 procollagen C-endopeptidase enhancer 2 affects response to substance ISO PCOLCE2 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114
JBrowse link
G Pcp4 Purkinje cell protein 4 decreases expression EXP Methamphetamine results in decreased expression of PCP4 mRNA CTD PMID:32035215 NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PCSK1 mRNA
Methamphetamine results in increased expression of PCSK1 mRNA
CTD PMID:19564919 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
JBrowse link
G Pcyox1l prenylcysteine oxidase 1 like decreases expression EXP Methamphetamine results in decreased expression of PCYOX1L mRNA CTD PMID:19564919 NCBI chr18:55,150,637...55,161,334
Ensembl chr18:55,150,650...55,161,327
JBrowse link
G Pcyt2 phosphate cytidylyltransferase 2, ethanolamine affects methylation
increases expression
ISO Methamphetamine affects the methylation of PCYT2 promoter
Methamphetamine results in increased expression of PCYT2 mRNA
CTD PMID:26307267 NCBI chr10:105,888,769...105,896,182
Ensembl chr10:105,888,775...105,896,172
JBrowse link
G Pde1b phosphodiesterase 1B affects response to substance ISO PDE1B protein affects the susceptibility to Methamphetamine CTD PMID:12077213 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580
JBrowse link
G Pde2a phosphodiesterase 2A increases expression
increases methylation
ISO Methamphetamine results in increased expression of PDE2A mRNA
Methamphetamine results in increased methylation of PDE2A promoter
CTD PMID:26307267 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pde4b phosphodiesterase 4B affects response to substance ISO PDE4B gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pde4d phosphodiesterase 4D affects response to substance ISO PDE4D gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein increases expression ISO Methamphetamine results in increased expression of PDE4DIP mRNA CTD PMID:26307267 NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379
JBrowse link
G Pde6c phosphodiesterase 6C affects response to substance ISO PDE6C gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315
JBrowse link
G Pde8a phosphodiesterase 8A multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PDE8A mRNA
Methamphetamine results in decreased expression of PDE8A mRNA
CTD PMID:19564919 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of PDGFB mRNA
Luteolin inhibits the reaction [Methamphetamine results in increased expression of PDGFB mRNA]
CTD PMID:26307267 PMID:32035215 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression EXP Methamphetamine results in decreased expression of PDGFRA mRNA CTD PMID:28619521 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 decreases expression EXP Methamphetamine results in decreased expression of PDHA1 protein CTD PMID:19826936 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta increases expression EXP Methamphetamine results in increased expression of PDHB protein CTD PMID:19826936 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression EXP Methamphetamine results in decreased expression of PDIA3 protein CTD PMID:19826936 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of PDIA4 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PDIA4 mRNA]
CTD PMID:19564919 PMID:36914120 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 multiple interactions
increases expression
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in increased expression of PDK4 mRNA
Methamphetamine results in increased expression of PDK4 mRNA
CTD PMID:19564919 PMID:36914120 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdlim7 PDZ and LIM domain 7 increases expression EXP Methamphetamine results in increased expression of PDLIM7 mRNA CTD PMID:19564919 NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811
JBrowse link
G Pdp1 pyruvate dehydrogenase phosphatase catalytic subunit 1 increases expression EXP Methamphetamine results in increased expression of PDP1 mRNA CTD PMID:19564919 NCBI chr 5:25,446,843...25,455,107
Ensembl chr 5:25,446,272...25,455,217
JBrowse link
G Pdxkl1 pyridoxal kinase like 1 increases expression EXP Methamphetamine results in increased expression of PDXK mRNA CTD PMID:19564919 NCBI chr20:10,162,934...10,192,572
Ensembl chr20:10,164,099...10,192,739
JBrowse link
G Pdyn prodynorphin increases response to substance
multiple interactions
decreases expression
increases expression
ISO
EXP
PDYN promoter polymorphism results in increased susceptibility to Methamphetamine
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [[PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [PDYN gene mutant form results in increased susceptibility to Methamphetamine]; [PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of PDYN mRNA]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of TAC1 mRNA]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]
Methamphetamine results in decreased expression of PDYN mRNA; Methamphetamine results in decreased expression of PDYN protein
Methamphetamine results in increased expression of PDYN mRNA
CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of PDYN mRNA]
CTD PMID:16529859 PMID:20298714 PMID:29467000 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression EXP Methamphetamine results in increased expression of PEBP1 protein CTD PMID:19826936 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 multiple interactions
increases expression
ISO PELI1 protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of IL6 protein]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of TNF protein]
Methamphetamine results in increased expression of PELI1 protein
CTD PMID:32768653 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PEMT mRNA
Methamphetamine results in decreased expression of PEMT mRNA
CTD PMID:19564919 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
JBrowse link
G Penk proenkephalin increases expression EXP Methamphetamine results in increased expression of PENK mRNA CTD PMID:19149911 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Per1 period circadian regulator 1 increases expression EXP
ISO
Methamphetamine results in increased expression of PER1 mRNA CTD PMID:19564919 PMID:26307267 PMID:35863504 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Per2 period circadian regulator 2 increases expression
decreases expression
ISO
EXP
Methamphetamine results in increased expression of PER2 mRNA; Methamphetamine results in increased expression of PER2 protein
Methamphetamine results in decreased expression of PER2 mRNA
CTD PMID:15542705 PMID:15950759 PMID:19564919 PMID:35863504 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Per3 period circadian regulator 3 increases expression EXP Methamphetamine results in increased expression of PER3 mRNA CTD PMID:35863504 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
JBrowse link
G Pex6 peroxisomal biogenesis factor 6 increases expression ISO Methamphetamine results in increased expression of PEX6 mRNA CTD PMID:26307267 NCBI chr 9:14,258,145...14,270,335
Ensembl chr 9:14,258,145...14,270,303
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of PFKFB2 promoter
Methamphetamine results in increased expression of PFKFB2 mRNA
CTD PMID:26307267 NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699
JBrowse link
G Pfkm phosphofructokinase, muscle increases expression ISO Methamphetamine results in increased expression of PFKM mRNA CTD PMID:26307267 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pfn2 profilin 2 affects expression EXP Methamphetamine affects the expression of PFN2 protein CTD PMID:17904249 NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions
increases expression
decreases expression
ISO (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of PGAM1 mRNA]
Methamphetamine results in increased expression of PGAM1 mRNA
CTD PMID:11756511 PMID:36914120 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgap6 post-GPI attachment to proteins 6 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of PGAP6 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PGAP6 mRNA
CTD PMID:19564919 NCBI chr10:15,138,918...15,148,431
Ensembl chr10:15,138,959...15,148,431
JBrowse link
G Pgbd5 piggyBac transposable element derived 5 increases expression EXP Methamphetamine results in increased expression of PGBD5 mRNA CTD PMID:28341135 NCBI chr19:52,336,751...52,401,906
Ensembl chr19:52,336,751...52,402,397
JBrowse link
G Pgghg protein-glucosylgalactosylhydroxylysine glucosidase increases expression ISO Methamphetamine results in increased expression of PGGHG mRNA CTD PMID:26307267 NCBI chr 1:196,038,276...196,044,561
Ensembl chr 1:196,039,103...196,044,372
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression EXP Methamphetamine results in decreased expression of PGK1 protein CTD PMID:19826936 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 increases expression ISO Methamphetamine results in increased expression of PGS1 mRNA CTD PMID:26307267 NCBI chr10:103,214,635...103,250,254
Ensembl chr10:103,214,646...103,250,254
JBrowse link
G Phb1 prohibitin 1 increases expression EXP Methamphetamine results in increased expression of PHB1 protein CTD PMID:19826936 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Phf13 PHD finger protein 13 increases expression EXP Methamphetamine results in increased expression of PHF13 mRNA CTD PMID:19564919 NCBI chr 5:162,494,574...162,501,350
Ensembl chr 5:162,494,573...162,501,350
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression EXP Methamphetamine results in decreased expression of PHGDH protein CTD PMID:19826936 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phkg1 phosphorylase kinase catalytic subunit gamma 1 decreases expression EXP Methamphetamine results in decreased expression of PHKG1 mRNA CTD PMID:19564919 NCBI chr12:26,838,822...26,854,547
Ensembl chr12:26,838,968...26,852,850
JBrowse link
G Phldb1 pleckstrin homology-like domain, family B, member 1 increases expression ISO Methamphetamine results in increased expression of PHLDB1 mRNA CTD PMID:26307267 NCBI chr 8:45,003,543...45,051,541
Ensembl chr 8:45,003,538...45,051,522
JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 affects expression
increases expression
ISO Methamphetamine affects the expression of PHLPP1 mRNA
Methamphetamine results in increased expression of PHLPP1 protein
CTD PMID:15542705 PMID:15950759 NCBI chr13:22,308,532...22,530,978
Ensembl chr13:22,308,548...22,530,977
JBrowse link
G Phrf1 PHD and ring finger domains 1 affects methylation
increases expression
ISO Methamphetamine affects the methylation of PHRF1 promoter
Methamphetamine results in increased expression of PHRF1 mRNA
CTD PMID:26307267 NCBI chr 1:196,333,663...196,366,901
Ensembl chr 1:196,333,903...196,366,892
JBrowse link
G Pick1 protein interacting with PRKCA 1 increases response to substance
increases expression
ISO PICK1 gene SNP results in increased susceptibility to Methamphetamine
Methamphetamine results in increased expression of PICK1 mRNA
CTD PMID:17606663 PMID:26307267 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 decreases expression ISO Methamphetamine results in decreased expression of PIK3AP1 mRNA CTD PMID:26307267 NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 decreases expression ISO Methamphetamine results in decreased expression of PIK3IP1 mRNA CTD PMID:36914120 NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases methylation ISO Methamphetamine results in increased methylation of PIK3R1 promoter CTD PMID:26307267 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of PIK3R5 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PIK3R5 mRNA
CTD PMID:19564919 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
JBrowse link
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of PIK3R6 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of PIK3R6 mRNA
CTD PMID:19564919 NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243
JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha decreases expression ISO Methamphetamine results in decreased expression of PILRA mRNA CTD PMID:26307267 NCBI chr12:17,787,169...17,798,149
Ensembl chr12:17,787,127...17,798,094
JBrowse link
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase decreases expression ISO Methamphetamine results in decreased expression of PIM3 mRNA CTD PMID:36914120 NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587
JBrowse link
G Pimreg PICALM interacting mitotic regulator decreases expression EXP Methamphetamine results in decreased expression of PIMREG mRNA CTD PMID:28341135 NCBI chr10:56,669,603...56,674,540
Ensembl chr10:56,669,675...56,674,791
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha increases expression ISO Methamphetamine results in increased expression of PIP5K1A mRNA CTD PMID:26307267 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
JBrowse link
G Pitx3 paired-like homeodomain 3 affects expression
multiple interactions
EXP Methamphetamine affects the expression of PITX3 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PITX3 mRNA
CTD PMID:19564919 NCBI chr 1:245,001,106...245,013,881
Ensembl chr 1:245,001,164...245,013,892
JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic increases expression ISO Methamphetamine results in increased expression of PKDCC mRNA CTD PMID:36914120 NCBI chr 6:11,455,686...11,465,002
Ensembl chr 6:11,455,686...11,465,556
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP Methamphetamine results in increased expression of PKM protein CTD PMID:19826936 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Pkn3 protein kinase N3 increases expression ISO Methamphetamine results in increased expression of PKN3 mRNA CTD PMID:26307267 NCBI chr 3:13,350,082...13,363,572
Ensembl chr 3:13,335,041...13,363,567
JBrowse link
G Pkp2 plakophilin 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PKP2 mRNA
Methamphetamine results in increased expression of PKP2 mRNA
CTD PMID:19564919 NCBI chr11:84,661,783...84,727,730
Ensembl chr11:84,661,783...84,727,730
JBrowse link
G Pla1a phospholipase A1 member A multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PLA1A mRNA
Methamphetamine results in increased expression of PLA1A mRNA
CTD PMID:19564919 NCBI chr11:62,320,112...62,357,779
Ensembl chr11:62,320,493...62,357,779
JBrowse link
G Pla2g5 phospholipase A2, group V increases expression ISO Methamphetamine results in increased expression of PLA2G5 mRNA CTD PMID:25290377 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PLAGL1 mRNA
Methamphetamine results in increased expression of PLAGL1 mRNA
CTD PMID:19564919 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
JBrowse link
G Plat plasminogen activator, tissue type increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of PLAT mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of PLAT mRNA
Raclopride inhibits the reaction [Methamphetamine results in increased expression of PLAT mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PLAT mRNA]
CTD PMID:15659235 PMID:19564919 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plcb1 phospholipase C beta 1 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of PLCB1 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of PLCB1 mRNA]
Methamphetamine results in increased expression of PLCB1 mRNA; Methamphetamine results in increased expression of PLCB1 protein
candesartan cilexetil inhibits the reaction [Methamphetamine results in increased expression of PLCB1 protein]
CTD PMID:33421459 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plcd1 phospholipase C, delta 1 decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of PLCD1 promoter
Methamphetamine results in increased expression of PLCD1 mRNA
CTD PMID:26307267 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186
JBrowse link
G Plcd3 phospholipase C, delta 3 increases expression ISO Methamphetamine results in increased expression of PLCD3 mRNA CTD PMID:26307267 NCBI chr10:88,026,707...88,048,080
Ensembl chr10:88,026,740...88,048,296
JBrowse link
G Plec plectin increases expression ISO Methamphetamine results in increased expression of PLEC mRNA CTD PMID:26307267 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
JBrowse link
G Plekha6 pleckstrin homology domain containing A6 increases expression ISO Methamphetamine results in increased expression of PLEKHA6 mRNA CTD PMID:26307267 NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of PLEKHF1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of PLEKHF1 mRNA
CTD PMID:19564919 NCBI chr 1:90,908,304...90,915,862
Ensembl chr 1:90,904,742...90,915,820
JBrowse link
G Plekhg2 pleckstrin homology and RhoGEF domain containing G2 increases expression ISO Methamphetamine results in increased expression of PLEKHG2 mRNA CTD PMID:26307267 NCBI chr 1:83,651,902...83,665,063
Ensembl chr 1:83,647,748...83,665,063
JBrowse link
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 increases expression ISO Methamphetamine results in increased expression of PLEKHG5 mRNA CTD PMID:26307267 NCBI chr 5:162,577,999...162,621,518
Ensembl chr 5:162,578,071...162,621,513
JBrowse link
G Plekhj1 pleckstrin homology domain containing J1 decreases expression EXP Methamphetamine results in decreased expression of PLEKHJ1 mRNA CTD PMID:19564919 NCBI chr 7:8,915,492...8,920,491 JBrowse link
G Plekhm2 pleckstrin homology and RUN domain containing M2 increases expression
affects methylation
ISO Methamphetamine results in increased expression of PLEKHM2 mRNA
Methamphetamine affects the methylation of PLEKHM2 promoter
CTD PMID:26307267 NCBI chr 5:153,939,582...153,978,625
Ensembl chr 5:153,940,262...153,978,689
JBrowse link
G Plekhn1 pleckstrin homology domain containing N1 increases expression ISO Methamphetamine results in increased expression of PLEKHN1 mRNA CTD PMID:26307267 NCBI chr 5:166,805,309...166,813,339
Ensembl chr 5:166,804,837...166,813,155
JBrowse link
G Plekho1 pleckstrin homology domain containing O1 increases expression ISO Methamphetamine results in increased expression of PLEKHO1 mRNA CTD PMID:26307267 NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785
JBrowse link
G Plk3 polo-like kinase 3 increases expression EXP Methamphetamine results in increased expression of PLK3 mRNA CTD PMID:19564919 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Plppr2 phospholipid phosphatase related 2 increases expression ISO Methamphetamine results in increased expression of PLPPR2 mRNA CTD PMID:26307267 NCBI chr 8:20,467,071...20,479,474
Ensembl chr 8:20,467,071...20,479,474
JBrowse link
G Plscr2 phospholipid scramblase 2 increases expression EXP Methamphetamine results in increased expression of PLSCR2 mRNA CTD PMID:19564919 NCBI chr 8:92,809,422...92,845,947
Ensembl chr 8:92,808,398...92,845,932
JBrowse link
G Pmch pro-melanin-concentrating hormone affects expression
multiple interactions
EXP Methamphetamine affects the expression of PMCH mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of PMCH mRNA
CTD PMID:19564919 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 increases expression EXP Methamphetamine results in increased expression of PMEPA1 mRNA CTD PMID:19564919 NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Pnlip pancreatic lipase decreases expression EXP Methamphetamine results in decreased expression of PNLIP mRNA CTD PMID:15644446 NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654
JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 increases expression ISO Methamphetamine results in increased expression of PNPLA7 mRNA CTD PMID:26307267 NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497
JBrowse link
G Podxl podocalyxin-like decreases expression EXP Methamphetamine results in decreased expression of PODXL mRNA CTD PMID:15644446 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
JBrowse link
G Pola2 DNA polymerase alpha 2, accessory subunit increases expression ISO Methamphetamine results in increased expression of POLA2 mRNA CTD PMID:26307267 NCBI chr 1:203,227,183...203,251,350
Ensembl chr 1:203,203,388...203,251,348
JBrowse link
G Poll DNA polymerase lambda decreases expression EXP Methamphetamine results in decreased expression of POLL mRNA CTD PMID:19564919 NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662
JBrowse link
G Polr3e RNA polymerase III subunit E decreases expression EXP Methamphetamine results in decreased expression of POLR3E mRNA CTD PMID:19564919 NCBI chr 1:175,466,091...175,494,679
Ensembl chr 1:175,466,127...175,494,667
JBrowse link
G Polr3gl RNA polymerase III subunit GL decreases expression EXP Methamphetamine results in decreased expression of POLR3GL mRNA CTD PMID:35863504 NCBI chr 2:184,111,570...184,129,200
Ensembl chr 2:184,112,510...184,129,114
JBrowse link
G Pom121l12 POM121 transmembrane nucleoporin-like 12 decreases expression ISO Methamphetamine results in decreased expression of POM121L12 mRNA CTD PMID:26307267 NCBI chr14:89,108,535...89,109,604
Ensembl chr14:89,108,572...89,109,408
JBrowse link
G Pou5f1 POU class 5 homeobox 1 affects response to substance ISO POU5F1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases response to substance
increases activity
increases expression
decreases expression
ISO 2-chloro-5-nitrobenzanilide promotes the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; [pioglitazone co-treated with alitretinoin] inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; ciglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; Ibuprofen inhibits the reaction [Methamphetamine results in decreased expression of PPARG protein]; pioglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]
Methamphetamine results in increased activity of PPARG protein
Methamphetamine results in increased expression of PPARG protein
CTD PMID:17019405 PMID:18946735 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Methamphetamine results in increased expression of PPARGC1A mRNA CTD PMID:26307267 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppia peptidylprolyl isomerase A decreases expression EXP Methamphetamine results in decreased expression of PPIA mRNA CTD PMID:15644446 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppic peptidylprolyl isomerase C decreases expression ISO Methamphetamine results in decreased expression of PPIC mRNA CTD PMID:36914120 NCBI chr18:46,842,410...46,855,016
Ensembl chr18:46,842,409...46,855,017
JBrowse link
G Ppih peptidylprolyl isomerase H decreases methylation ISO Methamphetamine results in decreased methylation of PPIH promoter CTD PMID:26307267 NCBI chr 5:132,906,324...132,924,341
Ensembl chr 5:132,906,328...132,924,267
JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PPIP5K2 mRNA
Methamphetamine results in increased expression of PPIP5K2 mRNA
CTD PMID:19564919 NCBI chr 9:98,315,220...98,394,537
Ensembl chr 9:98,315,252...98,390,814
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression EXP Methamphetamine results in increased expression of PPM1D mRNA CTD PMID:19564919 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A decreases expression EXP Methamphetamine results in decreased expression of PPP1R14A mRNA CTD PMID:19564919 NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions
increases expression
EXP SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP1R15A mRNA] CTD PMID:19564919 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions
increases expression
increases phosphorylation
ISO
EXP
naloxonazine inhibits the reaction [Methamphetamine results in increased phosphorylation of PPP1R1B protein]
Methamphetamine results in increased expression of PPP1R1B mRNA
CTD PMID:22564758 PMID:28341135 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A decreases expression EXP Methamphetamine results in decreased expression of PPP1R9A mRNA CTD PMID:15644446 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907
JBrowse link
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha increases expression ISO Methamphetamine results in increased expression of PPP2R3A mRNA CTD PMID:26307267 NCBI chr 8:101,703,512...101,841,530
Ensembl chr 8:101,704,778...101,841,502
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression
multiple interactions
EXP Methamphetamine results in increased expression of PPP3CA protein
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3CA protein]
CTD PMID:15644446 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta increases expression
multiple interactions
EXP Methamphetamine results in increased expression of PPP3CB protein
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3CB protein]
CTD PMID:15644446 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha affects expression EXP Methamphetamine affects the expression of PPP3R1 protein CTD PMID:17904249 NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta increases expression
multiple interactions
EXP Methamphetamine results in increased expression of PPP3R2 protein
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3R2 protein]
CTD PMID:15644446 NCBI chr 5:64,026,903...64,027,898
Ensembl chr 5:64,026,903...64,032,548
JBrowse link
G Ppp6r1 protein phosphatase 6, regulatory subunit 1 increases expression ISO Methamphetamine results in increased expression of PPP6R1 mRNA CTD PMID:26307267 NCBI chr 1:69,190,856...69,217,598
Ensembl chr 1:69,189,822...69,216,272
JBrowse link
G Ppp6r2 protein phosphatase 6, regulatory subunit 2 increases expression ISO Methamphetamine results in increased expression of PPP6R2 mRNA CTD PMID:26307267 NCBI chr 7:120,285,378...120,356,995
Ensembl chr 7:120,285,406...120,356,395
JBrowse link
G Pptc7 protein phosphatase targeting COQ7 increases expression EXP Methamphetamine results in increased expression of PPTC7 mRNA CTD PMID:19564919 NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339
JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO Methamphetamine results in increased expression of PRDM1 mRNA CTD PMID:26307267 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Prdm16 PR/SET domain 16 affects methylation
increases expression
ISO Methamphetamine affects the methylation of PRDM16 promoter
Methamphetamine results in increased expression of PRDM16 mRNA
CTD PMID:26307267 NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601
JBrowse link
G Prdm2 PR/SET domain 2 affects response to substance ISO PRDM2 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825
JBrowse link
G Prdx2 peroxiredoxin 2 increases expression
decreases expression
EXP
ISO
Methamphetamine results in increased expression of PRDX2 protein
Methamphetamine results in decreased expression of PRDX2 protein
CTD PMID:16181420 PMID:19826936 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prdx5 peroxiredoxin 5 increases expression EXP Methamphetamine results in increased expression of PRDX5 mRNA CTD PMID:19149911 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Prg4 proteoglycan 4 affects expression
multiple interactions
EXP Methamphetamine affects the expression of PRG4 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of PRG4 mRNA
CTD PMID:19564919 NCBI chr13:62,487,257...62,504,657
Ensembl chr13:62,487,257...62,504,119
JBrowse link
G Prickle3 prickle planar cell polarity protein 3 increases expression EXP Methamphetamine results in increased expression of PRICKLE3 mRNA CTD PMID:19564919 NCBI chr  X:14,837,647...14,849,305
Ensembl chr  X:14,837,650...14,848,218
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
increases expression
ISO 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of PRKCA mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of PRKCA protein]
Methamphetamine results in increased expression of PRKCA mRNA; Methamphetamine results in increased expression of PRKCA protein
CTD PMID:33421459 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcd protein kinase C, delta affects localization
multiple interactions
affects response to substance
increases expression
increases response to substance
ISO Methamphetamine affects the localization of PRKCD protein
ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein]; Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein; PRKCD protein affects the reaction [Methamphetamine affects the localization of PRKCD protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD2 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein]
PRKCD protein affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of PRKCD protein
PRKCD results in increased susceptibility to Methamphetamine
[rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased activity of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of DAT protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in increased metabolism of Dopamine]; [rottlerin results in decreased activity of PRKCD protein] which results in decreased susceptibility to Methamphetamine; ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; Methamphetamine promotes the reaction [PRKCD protein modified form binds to EPHX1 protein]; Methamphetamine results in increased cleavage of and results in increased phosphorylation of PRKCD protein; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD affects the reaction [Methamphetamine results in increased activity of SOD2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of DAT protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of EPHX1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased metabolism of Dopamine]
CTD PMID:22512859 PMID:24430743 PMID:25523949 PMID:31422080 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions
increases expression
EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of PRKCE mRNA] CTD PMID:19149911 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkd2 protein kinase D2 increases expression EXP Methamphetamine results in increased expression of PRKD2 mRNA CTD PMID:19564919 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 affects response to substance ISO PRKG1 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases expression
multiple interactions
EXP
ISO
Methamphetamine results in decreased expression of PRKN protein
CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; PRKN protein inhibits the reaction [Methamphetamine results in decreased expression of PRKN protein]; PRKN protein inhibits the reaction [Methamphetamine results in increased expression of SNCA protein]; TRIB3 protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]
CTD PMID:28661099 PMID:31059759 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Prkx protein kinase cAMP-dependent X-linked catalytic subunit increases expression EXP Methamphetamine results in increased expression of PRKX mRNA CTD PMID:19564919 NCBI chr  X:41,823,349...41,866,844
Ensembl chr  X:41,823,355...41,866,669
JBrowse link
G Prl prolactin affects expression ISO Methamphetamine affects the expression of PRL protein CTD PMID:21142706 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prl5a2 prolactin family 5, subfamily A, member 2 increases expression EXP Methamphetamine results in increased expression of PRL5A2 mRNA CTD PMID:28341135 NCBI chr17:36,452,712...36,459,054
Ensembl chr17:36,452,718...36,459,054
JBrowse link
G Prodh proline dehydrogenase increases expression ISO Methamphetamine results in increased expression of PRODH mRNA CTD PMID:26307267 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305
JBrowse link
G Prok2 prokineticin 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of PROK2 mRNA
Methamphetamine results in increased expression of PROK2 mRNA
CTD PMID:19564919 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
JBrowse link
G Prokr2 prokineticin receptor 2 affects response to substance ISO PROKR2 gene SNP affects the susceptibility to Methamphetamine CTD PMID:20576534 NCBI chr 3:119,624,738...119,639,442
Ensembl chr 3:119,627,601...119,635,718
JBrowse link
G Prom1 prominin 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PROM1 mRNA
Methamphetamine results in decreased expression of PROM1 mRNA
CTD PMID:19564919 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
JBrowse link
G Prox2 prospero homeobox 2 decreases expression ISO Methamphetamine results in decreased expression of PROX2 mRNA CTD PMID:26307267 NCBI chr 6:104,731,385...104,758,619
Ensembl chr 6:104,733,002...104,742,093
JBrowse link
G Prp2l1 proline rich protein 2-like 1 decreases expression EXP Methamphetamine results in decreased expression of PRP2L1 mRNA CTD PMID:15644446 NCBI chr10:88,462,262...88,540,642
Ensembl chr10:88,462,289...88,523,061
JBrowse link
G Prr13 proline rich 13 increases expression ISO Methamphetamine results in increased expression of PRR13 mRNA CTD PMID:26307267 NCBI chr 7:133,592,511...133,595,817
Ensembl chr 7:133,592,490...133,601,005
JBrowse link
G Prr14l proline rich 14-like increases expression EXP Methamphetamine results in increased expression of PRR14L mRNA CTD PMID:28341135 NCBI chr14:77,869,848...77,937,141
Ensembl chr14:77,869,799...77,936,521
JBrowse link
G Prr5l proline rich 5 like increases expression EXP Methamphetamine results in increased expression of PRR5L mRNA CTD PMID:19564919 NCBI chr 3:88,001,951...88,173,532
Ensembl chr 3:88,003,617...88,082,763
JBrowse link
G Prrc2c proline-rich coiled-coil 2C decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of PRRC2C promoter
Methamphetamine results in increased expression of PRRC2C mRNA
CTD PMID:26307267 NCBI chr13:75,003,995...75,073,701
Ensembl chr13:75,004,010...75,073,643
JBrowse link
G Prune2 prune homolog 2 with BCH domain increases expression ISO Methamphetamine results in increased expression of PRUNE2 mRNA CTD PMID:26307267 NCBI chr 1:214,352,586...214,624,848
Ensembl chr 1:214,352,955...214,622,650
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression EXP Methamphetamine results in increased expression of PSAT1 mRNA CTD PMID:28341135 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 affects response to substance
increases expression
ISO PSD3 gene SNP affects the susceptibility to Methamphetamine
Methamphetamine results in increased expression of PSD3 mRNA
CTD PMID:18316681 PMID:26307267 NCBI chr16:21,465,643...22,035,846
Ensembl chr16:21,465,639...22,034,547
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression EXP Methamphetamine results in decreased expression of PSMA1 protein CTD PMID:19826936 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
JBrowse link
G Psma2 proteasome 20S subunit alpha 2 decreases expression EXP Methamphetamine results in decreased expression of PSMA2 protein CTD PMID:19826936 NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 decreases expression EXP Methamphetamine results in decreased expression of PSMA5 mRNA CTD PMID:15644446 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 decreases expression EXP Methamphetamine results in decreased expression of PSMC3 protein CTD PMID:19826936 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
JBrowse link
G Pten phosphatase and tensin homolog increases expression
multiple interactions
EXP Methamphetamine results in increased expression of PTEN mRNA; Methamphetamine results in increased expression of PTEN protein
Luteolin inhibits the reaction [Methamphetamine results in increased expression of PTEN protein]
CTD PMID:19564919 PMID:32035215 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgis prostaglandin I2 synthase decreases expression ISO Methamphetamine results in decreased expression of PTGIS mRNA CTD PMID:36914120 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions
increases response to substance
ISO [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [PTGS1 protein results in increased susceptibility to Methamphetamine] CTD PMID:21163909 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
increases response to substance
ISO
EXP
[[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [PTGS2 protein results in increased susceptibility to Methamphetamine]
Methamphetamine results in increased expression of PTGS2 mRNA
Methamphetamine results in increased expression of PTGS2 protein
CTD PMID:10698006 PMID:15644446 PMID:15718289 PMID:19564919 PMID:21163909 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of PTH1R mRNA
Methamphetamine results in decreased expression of PTH1R mRNA
CTD PMID:19564919 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of PTPN5 protein alternative form
3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine inhibits the reaction [Methamphetamine results in decreased expression of PTPN5 protein alternative form]
CTD PMID:23711322 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S increases expression ISO Methamphetamine results in increased expression of PTPRS mRNA CTD PMID:26307267 NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947
JBrowse link
G Pum1 pumilio RNA-binding family member 1 increases expression ISO Methamphetamine results in increased expression of PUM1 mRNA CTD PMID:15542705 NCBI chr 5:142,836,933...142,954,331
Ensembl chr 5:142,837,127...142,954,039
JBrowse link
G Purb purine rich element binding protein B increases expression ISO Methamphetamine results in increased expression of PURB mRNA CTD PMID:26307267 NCBI chr14:81,342,374...81,344,857
Ensembl chr14:81,336,448...81,351,432
JBrowse link
G Pusl1 pseudouridine synthase like 1 decreases expression EXP Methamphetamine results in decreased expression of PUSL1 mRNA CTD PMID:19564919 NCBI chr 5:166,497,643...166,500,647
Ensembl chr 5:166,496,755...166,500,611
JBrowse link
G Pvr PVR cell adhesion molecule increases expression EXP Methamphetamine results in increased expression of PVR mRNA CTD PMID:19564919 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Pxn paxillin increases expression ISO Methamphetamine results in increased expression of PXN mRNA CTD PMID:26307267 NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions
increases expression
decreases expression
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PYCARD mRNA
Methamphetamine results in increased expression of PYCARD protein
Methamphetamine promotes the reaction [PYCARD protein binds to NLRP3 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased cleavage of CASP1 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased expression of NLRP3 protein]
Methamphetamine results in decreased expression of PYCARD mRNA
CTD PMID:19564919 PMID:30394308 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of QARS1 mRNA
Lithium inhibits the reaction [Methamphetamine results in decreased expression of QARS1 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of QARS1 mRNA]
CTD PMID:19149911 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739
JBrowse link
G Qprt quinolinate phosphoribosyltransferase decreases expression EXP Methamphetamine results in decreased expression of QPRT mRNA CTD PMID:19564919 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
JBrowse link
G Rab30 RAB30, member RAS oncogene family increases expression EXP Methamphetamine results in increased expression of RAB30 mRNA CTD PMID:19564919 NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181
JBrowse link
G Rab3d RAB3D, member RAS oncogene family multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RAB3D mRNA
Methamphetamine results in decreased expression of RAB3D mRNA
CTD PMID:19564919 NCBI chr 8:20,438,622...20,449,269
Ensembl chr 8:20,439,294...20,449,185
JBrowse link
G Rab5a RAB5A, member RAS oncogene family increases expression EXP Methamphetamine results in increased expression of RAB5A protein CTD PMID:34374793 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rab7a RAB7A, member RAS oncogene family increases expression EXP Methamphetamine results in increased expression of RAB7 mRNA; Methamphetamine results in increased expression of RAB7 protein CTD PMID:34374793 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Rabep1 rabaptin, RAB GTPase binding effector protein 1 increases expression EXP Methamphetamine results in increased expression of RABEP1 protein CTD PMID:19826936 NCBI chr10:55,566,156...55,667,595
Ensembl chr10:55,566,185...55,665,973
JBrowse link
G Rabif RAB interacting factor increases expression
decreases expression
EXP Methamphetamine results in increased expression of RABIF protein
Methamphetamine results in decreased expression of RABIF mRNA
CTD PMID:19564919 PMID:19826936 NCBI chr13:45,936,371...45,948,929
Ensembl chr13:45,936,369...45,949,775
JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase decreases expression ISO Methamphetamine results in decreased expression of RAD18 mRNA CTD PMID:26307267 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression ISO Methamphetamine results in decreased expression of RAD51AP1 mRNA CTD PMID:25290377 NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524
JBrowse link
G Rad52 RAD52 homolog, DNA repair protein decreases expression EXP Methamphetamine results in decreased expression of RAD52 mRNA CTD PMID:19564919 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
G Rad54l RAD54 like increases methylation ISO Methamphetamine results in increased methylation of RAD54L promoter CTD PMID:26307267 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Ralgapa1 Ral GTPase activating protein catalytic subunit alpha 1 increases expression ISO Methamphetamine results in increased expression of RALGAPA1 mRNA CTD PMID:26307267 NCBI chr 6:72,977,432...73,252,378
Ensembl chr 6:72,977,432...73,252,378
JBrowse link
G Ralgapa2 Ral GTPase activating protein catalytic subunit alpha 2 increases methylation ISO Methamphetamine results in increased methylation of RALGAPA2 promoter CTD PMID:26307267 NCBI chr 3:133,658,725...133,938,821
Ensembl chr 3:133,659,761...133,938,916
JBrowse link
G Ralgdsl2 ral guanine nucleotide dissociation stimulator like 2 increases expression ISO Methamphetamine results in increased expression of RGL2 mRNA CTD PMID:26307267 NCBI chr20:4,948,495...4,956,774
Ensembl chr20:4,948,497...4,969,911
JBrowse link
G Ralgps2 Ral GEF with PH domain and SH3 binding motif 2 decreases expression
decreases methylation
ISO Methamphetamine results in decreased expression of RALGPS2 mRNA
Methamphetamine results in decreased methylation of RALGPS2 promoter
CTD PMID:26307267 NCBI chr13:68,924,674...69,104,637
Ensembl chr13:68,928,474...69,056,549
JBrowse link
G Raly RALY heterogeneous nuclear ribonucleoprotein affects response to substance ISO RALY gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 3:143,306,039...143,370,542
Ensembl chr 3:143,306,300...143,370,539
JBrowse link
G Ramp2 receptor activity modifying protein 2 decreases expression
decreases methylation
increases expression
EXP
ISO
Methamphetamine results in decreased expression of RAMP2 mRNA
Methamphetamine results in decreased methylation of RAMP2 promoter
Methamphetamine results in increased expression of RAMP2 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Ranbp3 RAN binding protein 3 increases expression ISO Methamphetamine results in increased expression of RANBP3 mRNA CTD PMID:26307267 NCBI chr 9:1,507,233...1,544,460
Ensembl chr 9:1,507,361...1,544,460
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 increases expression ISO Methamphetamine results in increased expression of RAPGEF3 mRNA CTD PMID:26307267 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
JBrowse link
G Rapgef5 Rap guanine nucleotide exchange factor 5 affects response to substance ISO RAPGEF5 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 6:138,445,184...138,679,943
Ensembl chr 6:138,437,991...138,679,936
JBrowse link
G Rarg retinoic acid receptor, gamma increases expression ISO Methamphetamine results in increased expression of RARG mRNA CTD PMID:26307267 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Rasa4 RAS p21 protein activator 4 increases expression ISO Methamphetamine results in increased expression of RASA4 mRNA CTD PMID:26307267 NCBI chr12:20,552,805...20,580,177
Ensembl chr12:20,552,806...20,580,147
JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression EXP Methamphetamine results in increased expression of RASD1 mRNA CTD PMID:19564919 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 decreases expression EXP Methamphetamine results in decreased expression of RASGRP1 mRNA CTD PMID:15644446 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Rasgrp2 RAS guanyl releasing protein 2 increases expression ISO Methamphetamine results in increased expression of RASGRP2 mRNA CTD PMID:26307267 NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993
JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 increases expression ISO Methamphetamine results in increased expression of RASGRP3 mRNA CTD PMID:25290377 NCBI chr 6:19,895,361...19,993,945
Ensembl chr 6:19,895,390...19,958,578
JBrowse link
G Rasl11a RAS-like family 11 member A increases expression
multiple interactions
EXP Methamphetamine results in increased expression of RASL11A mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RASL11A mRNA
CTD PMID:19564919 NCBI chr12:8,258,148...8,260,909
Ensembl chr12:8,258,159...8,262,576
JBrowse link
G Rasl11b RAS-like family 11 member B increases expression ISO Methamphetamine results in increased expression of RASL11B mRNA CTD PMID:36914120 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152
JBrowse link
G Rassf9 Ras association domain family member 9 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of RASSF9 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RASSF9 mRNA
CTD PMID:19564919 NCBI chr 7:37,599,720...37,631,553
Ensembl chr 7:37,599,720...37,635,245
JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 decreases expression
multiple interactions
ISO Methamphetamine results in decreased expression of RBFOX3 protein
SNCA gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of RBFOX3 protein]
CTD PMID:29467000 PMID:32278788 NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935
JBrowse link
G Rbm20 RNA binding motif protein 20 increases expression ISO Methamphetamine results in increased expression of RBM20 mRNA CTD PMID:26307267 NCBI chr 1:252,683,760...252,907,465
Ensembl chr 1:252,683,771...252,886,060
JBrowse link
G Rbm25 RNA binding motif protein 25 increases expression ISO Methamphetamine results in increased expression of RBM25 mRNA CTD PMID:26307267 NCBI chr 6:103,271,775...103,319,090
Ensembl chr 6:103,271,801...103,317,854
JBrowse link
G Rbm28 RNA binding motif protein 28 increases expression ISO Methamphetamine results in increased expression of RBM28 mRNA CTD PMID:26307267 NCBI chr 4:57,722,946...57,761,935
Ensembl chr 4:57,722,223...57,761,653
JBrowse link
G Rbm3 RNA binding motif protein 3 decreases expression
multiple interactions
EXP
ISO
Methamphetamine results in decreased expression of RBM3 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM3 mRNA
CTD PMID:19564919 PMID:36914120 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580
JBrowse link
G Rbm43 RNA binding motif protein 43 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM43 mRNA
Methamphetamine results in decreased expression of RBM43 mRNA
CTD PMID:19564919 NCBI chr 3:36,394,431...36,404,757
Ensembl chr 3:36,395,346...36,404,816
JBrowse link
G Rbm5 RNA binding motif protein 5 increases expression
decreases methylation
ISO Methamphetamine results in increased expression of RBM5 mRNA
Methamphetamine results in decreased methylation of RBM5 promoter
CTD PMID:26307267 NCBI chr 8:108,420,220...108,449,481
Ensembl chr 8:108,420,222...108,449,430
JBrowse link
G Rbp7 retinol binding protein 7 decreases expression ISO Methamphetamine results in decreased expression of RBP7 mRNA CTD PMID:36914120 NCBI chr 5:159,889,723...159,894,338
Ensembl chr 5:159,889,723...159,894,339
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO Methamphetamine results in increased expression of RCAN1 mRNA CTD PMID:36914120 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects response to substance
increases phosphorylation
increases expression
increases activity
multiple interactions
affects localization
ISO
EXP
RELA mRNA affects the susceptibility to Methamphetamine
Methamphetamine results in increased phosphorylation of RELA protein
Methamphetamine results in increased expression of RELA mRNA; Methamphetamine results in increased expression of RELA protein
Methamphetamine results in increased activity of RELA protein
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; GPX1 protein affects the reaction [Methamphetamine results in increased activity of RELA protein]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]]; Methamphetamine results in increased expression of and results in increased phosphorylation of RELA protein; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of RELA protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of RELA protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA protein]
GATA4 protein affects the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of RELA protein]
Methamphetamine affects the localization of RELA protein
luzindole inhibits the reaction [Melatonin inhibits the reaction [Methamphetamine affects the localization of RELA protein]]; Melatonin inhibits the reaction [Methamphetamine affects the localization of RELA protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]
CTD PMID:19689456 PMID:26283214 PMID:27323860 PMID:30450033 PMID:32768653 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rem2 RRAD and GEM like GTPase 2 increases expression EXP Methamphetamine results in increased expression of REM2 mRNA CTD PMID:19564919 NCBI chr15:27,933,950...27,938,429
Ensembl chr15:27,933,950...27,938,429
JBrowse link
G Renbp renin binding protein increases expression ISO Methamphetamine results in increased expression of RENBP mRNA CTD PMID:25290377 NCBI chr  X:151,661,463...151,670,538
Ensembl chr  X:151,661,458...151,670,516
JBrowse link
G Rexo1 RNA exonuclease 1 homolog increases expression ISO Methamphetamine results in increased expression of REXO1 mRNA CTD PMID:26307267 NCBI chr 7:9,154,050...9,174,035
Ensembl chr 7:9,154,061...9,173,454
JBrowse link
G Rfpl4a ret finger protein-like 4A decreases expression ISO Methamphetamine results in decreased expression of RFPL4 mRNA CTD PMID:26307267 NCBI chr 1:68,728,964...68,735,423
Ensembl chr 1:68,728,964...68,735,423
JBrowse link
G Rgcc regulator of cell cycle decreases expression ISO Methamphetamine results in decreased expression of RGCC mRNA CTD PMID:36914120 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Rgs1 regulator of G-protein signaling 1 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of RGS1 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of RGS1 mRNA
CTD PMID:19564919 NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984
JBrowse link
G Rgs17 regulator of G-protein signaling 17 affects response to substance ISO RGS17 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 1:42,222,248...42,324,625
Ensembl chr 1:42,227,070...42,324,609
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP Methamphetamine results in increased expression of RGS2 mRNA CTD PMID:10098858 PMID:19564919 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs4 regulator of G-protein signaling 4 affects expression EXP Methamphetamine affects the expression of RGS4 mRNA CTD PMID:19126440 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rgs5 regulator of G-protein signaling 5 increases expression EXP Methamphetamine results in increased expression of RGS5 mRNA CTD PMID:32035215 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518
JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RHBDF1 mRNA
Methamphetamine results in decreased expression of RHBDF1 mRNA
CTD PMID:19564919 NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763
JBrowse link
G Rhob ras homolog family member B increases expression ISO Methamphetamine results in increased expression of RHOB mRNA CTD PMID:26307267 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rhod ras homolog family member D multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of RHOD mRNA
Methamphetamine results in increased expression of RHOD mRNA
CTD PMID:19564919 NCBI chr 1:201,708,699...201,724,405
Ensembl chr 1:201,708,699...201,722,632
JBrowse link
G Rig1 RNA sensor RIG-1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of RIGI mRNA
Methamphetamine results in decreased expression of RIGI mRNA
CTD PMID:19564919 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of RIMS2 mRNA
Methamphetamine results in increased expression of RIMS2 mRNA
CTD PMID:19564919 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491
JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 increases expression EXP Methamphetamine results in increased expression of RIPOR2 mRNA CTD PMID:19564919 NCBI chr17:40,323,748...40,547,482
Ensembl chr17:40,323,867...40,548,092
JBrowse link
G Ripply2 ripply transcriptional repressor 2 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of RIPPLY2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RIPPLY2 mRNA
CTD PMID:19564919 NCBI chr 8:87,974,444...87,979,002
Ensembl chr 8:87,974,776...87,978,969
JBrowse link
G Rlf RLF zinc finger increases expression EXP Methamphetamine results in increased expression of RLF mRNA CTD PMID:19564919 NCBI chr 5:134,711,612...134,767,274
Ensembl chr 5:134,711,619...134,767,257
JBrowse link
G Rmnd1 required for meiotic nuclear division 1 homolog increases expression ISO Methamphetamine results in increased expression of RMND1 mRNA CTD PMID:26307267 NCBI chr 1:40,859,829...40,894,376
Ensembl chr 1:40,859,829...40,894,314
JBrowse link
G Rnf113a1 ring finger protein 113A1 decreases expression EXP Methamphetamine results in decreased expression of RNF113A1 mRNA CTD PMID:19564919 NCBI chr  X:116,427,941...116,429,164
Ensembl chr  X:116,427,684...116,433,762
JBrowse link
G Rnf123 ring finger protein 123 increases expression ISO Methamphetamine results in increased expression of RNF123 mRNA CTD PMID:26307267 NCBI chr 8:108,740,176...108,768,177
Ensembl chr 8:108,739,620...108,767,675
JBrowse link
G Rnf13 ring finger protein 13 decreases expression ISO Methamphetamine results in decreased expression of RNF13 mRNA CTD PMID:26307267 NCBI chr 2:141,927,887...142,061,801
Ensembl chr 2:141,927,909...142,061,801
JBrowse link
G Rnf225 ring finger protein 225 affects expression
multiple interactions
EXP Methamphetamine affects the expression of RNF225 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of RNF225 mRNA
CTD PMID:19564919 NCBI chr 1:73,543,598...73,546,269
Ensembl chr 1:73,543,598...73,546,269
JBrowse link
G Rnf31 ring finger protein 31 decreases expression EXP Methamphetamine results in decreased expression of RNF31 mRNA CTD PMID:19564919 NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915
JBrowse link
G Rorc RAR-related orphan receptor C decreases expression
increases expression
EXP
ISO
Methamphetamine results in decreased expression of RORC mRNA
Methamphetamine results in increased expression of RORC mRNA
CTD PMID:35863504 PMID:36914120 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Rpl15 ribosomal protein L15 decreases expression ISO Methamphetamine results in decreased expression of RPL15 mRNA CTD PMID:26307267 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
JBrowse link
G Rpl30 ribosomal protein L30 decreases expression EXP Methamphetamine results in decreased expression of RPL30 mRNA CTD PMID:15644446 NCBI chr 7:65,648,266...65,651,401
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
JBrowse link
G Rpl39l1 ribosomal protein L39 like 1 increases expression ISO Methamphetamine results in increased expression of RPL39L mRNA CTD PMID:26307267 NCBI chr10:5,455,712...5,459,828
Ensembl chr10:5,454,559...5,462,029
JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 decreases expression EXP Methamphetamine results in decreased expression of RPLP2 mRNA CTD PMID:32035215 NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645
JBrowse link
G Rps27a ribosomal protein S27a decreases expression EXP Methamphetamine results in decreased expression of RPS27A mRNA CTD PMID:15644446 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011
JBrowse link
G Rps6 ribosomal protein S6 decreases expression EXP Methamphetamine results in decreased expression of RPS6 mRNA CTD PMID:15644446 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation EXP Methamphetamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34374793 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 decreases expression EXP Methamphetamine results in decreased expression of RPS6KB2 mRNA CTD PMID:32035215 NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078
JBrowse link
G Rpusd3 RNA pseudouridine synthase D3 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of RPUSD3 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RPUSD3 mRNA
CTD PMID:19564919 NCBI chr 4:146,553,743...146,562,789
Ensembl chr 4:146,558,562...146,562,794
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression ISO
EXP
Methamphetamine results in decreased expression of RRM2 mRNA
Methamphetamine results in decreased expression of RRM2 mRNA; Methamphetamine results in decreased expression of RRM2 protein
CTD PMID:25290377 PMID:28341135 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rsrp1 arginine and serine rich protein 1 decreases expression ISO Methamphetamine results in decreased expression of RSRP1 mRNA CTD PMID:36914120 NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523
JBrowse link
G RT1-CE16 RT1 class I, locus CE16 increases expression EXP Methamphetamine results in increased expression of RT1-CE16 mRNA CTD PMID:32035215 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
JBrowse link
G RT1-T24-4 RT1 class I, locus T24, gene 4 increases expression EXP Methamphetamine results in increased expression of RT1-T24-4 mRNA CTD PMID:32035215 NCBI chr20:2,684,515...2,747,878
Ensembl chr20:2,684,515...2,692,511
JBrowse link
G Rtkn2 rhotekin 2 decreases expression ISO Methamphetamine results in decreased expression of RTKN2 mRNA CTD PMID:26307267 NCBI chr20:20,536,628...20,609,951
Ensembl chr20:20,525,256...20,609,951
JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 increases expression EXP Methamphetamine results in increased expression of RTN4RL1 mRNA CTD PMID:28341135 NCBI chr10:60,043,246...60,116,977
Ensembl chr10:60,043,002...60,116,978
JBrowse link
G Rtp1 receptor (chemosensory) transporter protein 1 affects expression
multiple interactions
EXP Methamphetamine affects the expression of RTP1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RTP1 mRNA
CTD PMID:19564919 NCBI chr11:77,422,982...77,425,498
Ensembl chr11:77,422,982...77,425,498
JBrowse link
G Rwdd3 RWD domain containing 3 decreases expression EXP Methamphetamine results in decreased expression of RWDD3 mRNA CTD PMID:19564919 NCBI chr 2:209,233,622...209,254,842
Ensembl chr 2:209,233,622...209,248,853
JBrowse link
G Ryr2 ryanodine receptor 2 increases expression ISO Methamphetamine results in increased expression of RYR2 mRNA CTD PMID:36914120 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of S100A11 mRNA
Methamphetamine results in decreased expression of S100A11 mRNA
CTD PMID:19564919 NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
JBrowse link
G Sap18 Sin3A associated protein 18 decreases expression EXP Methamphetamine results in decreased expression of SAP18 mRNA CTD PMID:32035215 NCBI chr15:31,943,228...31,947,534
Ensembl chr15:31,943,230...31,950,038
Ensembl chr10:31,943,230...31,950,038
JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 decreases expression EXP Methamphetamine results in decreased expression of SARM1 mRNA CTD PMID:19564919 NCBI chr10:63,369,456...63,393,016
Ensembl chr10:63,369,456...63,392,822
JBrowse link
G Sars2 seryl-tRNA synthetase 2, mitochondrial decreases expression EXP Methamphetamine results in decreased expression of SARS2 mRNA CTD PMID:19564919 NCBI chr 1:84,028,972...84,040,725
Ensembl chr 1:84,028,986...84,040,725
JBrowse link
G Saxo1 stabilizer of axonemal microtubules 1 increases expression EXP Methamphetamine results in increased expression of SAXO1 mRNA CTD PMID:28341135 NCBI chr 5:100,937,134...101,093,308
Ensembl chr 5:100,937,130...101,093,281
JBrowse link
G Sbf1 SET binding factor 1 increases expression ISO Methamphetamine results in increased expression of SBF1 mRNA CTD PMID:26307267 NCBI chr 7:120,358,338...120,385,022
Ensembl chr 7:120,358,338...120,384,902
JBrowse link
G Scand1 SCAN domain-containing 1 increases expression ISO Methamphetamine results in increased expression of SCAND1 mRNA CTD PMID:36914120 NCBI chr 3:144,818,615...144,819,479
Ensembl chr 3:144,818,611...144,820,025
JBrowse link
G Scarf2 scavenger receptor class F, member 2 decreases expression EXP Methamphetamine results in decreased expression of SCARF2 mRNA CTD PMID:19564919 NCBI chr11:83,175,956...83,187,415
Ensembl chr11:83,175,963...83,187,348
JBrowse link
G Scg2 secretogranin II increases expression EXP Methamphetamine results in increased expression of SCG2 mRNA CTD PMID:19564919 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 decreases methylation
increases expression
ISO
EXP
Methamphetamine results in decreased methylation of SCN5A promoter
Methamphetamine results in increased expression of SCN5A mRNA
CTD PMID:26307267 PMID:35863504 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Scrg1 stimulator of chondrogenesis 1 decreases expression EXP Methamphetamine results in decreased expression of SCRG1 mRNA CTD PMID:28619521 NCBI chr16:32,760,028...32,788,299
Ensembl chr16:32,760,028...32,788,299
JBrowse link
G Scrt2 scratch family transcriptional repressor 2 increases expression EXP Methamphetamine results in increased expression of SCRT2 mRNA CTD PMID:19564919 NCBI chr 3:140,581,336...140,595,273
Ensembl chr 3:140,581,593...140,593,299
JBrowse link
G Sec14l1 SEC14-like lipid binding 1 affects methylation
increases expression
ISO Methamphetamine affects the methylation of SEC14L1 promoter
Methamphetamine results in increased expression of SEC14L1 mRNA
CTD PMID:26307267 NCBI chr10:102,319,920...102,367,070
Ensembl chr10:102,319,920...102,367,068
JBrowse link
G Sec24a SEC24 homolog A, COPII coat complex component increases expression EXP Methamphetamine results in increased expression of SEC24A mRNA CTD PMID:19564919 NCBI chr10:35,946,901...36,024,353
Ensembl chr10:35,947,031...36,024,353
JBrowse link
G Secisbp2 SECIS binding protein 2 increases expression ISO Methamphetamine results in increased expression of SECISBP2 mRNA CTD PMID:26307267 NCBI chr17:13,538,513...13,569,573
Ensembl chr17:13,538,513...13,569,523
JBrowse link
G Selenoi selenoprotein I decreases expression ISO Methamphetamine results in decreased expression of SELENOI mRNA CTD PMID:26307267 NCBI chr 6:26,073,127...26,111,326
Ensembl chr 6:26,072,648...26,111,314
JBrowse link
G Selenop selenoprotein P increases expression EXP Methamphetamine results in increased expression of SELENOP mRNA CTD PMID:32035215 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Septin3 septin 3 decreases expression EXP Methamphetamine results in decreased expression of SEPTIN3 protein CTD PMID:19826936 NCBI chr 7:113,783,217...113,811,089
Ensembl chr 7:113,783,095...113,811,087
JBrowse link
G Septin5 septin 5 decreases expression EXP Methamphetamine results in decreased expression of SEPTIN5 protein CTD PMID:19826936 NCBI chr11:82,373,601...82,379,393
Ensembl chr11:82,369,754...82,379,393
JBrowse link
G Serpina5 serpin family A member 5 affects response to substance ISO SERPINA5 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:123,023,306...123,028,407
JBrowse link
G Serpinb9 serpin family B member 9 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SERPINB9 mRNA
Methamphetamine results in decreased expression of SERPINB9 mRNA
CTD PMID:19564919 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO Methamphetamine results in increased expression of SERPINE1 mRNA CTD PMID:12766323 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinf1 serpin family F member 1 decreases expression ISO Methamphetamine results in decreased expression of SERPINF1 mRNA CTD PMID:36914120 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Sertad1 SERTA domain containing 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SERTAD1 mRNA
Methamphetamine results in increased expression of SERTAD1 mRNA
CTD PMID:19564919 NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091
JBrowse link
G Sesn2 sestrin 2 increases expression EXP Methamphetamine results in increased expression of SESN2 mRNA CTD PMID:28619521 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sfi1 SFI1 centrin binding protein decreases expression EXP Methamphetamine results in decreased expression of SFI1 mRNA CTD PMID:19564919 NCBI chr14:77,990,965...78,048,352
Ensembl chr14:77,990,965...78,048,255
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SFRP2 mRNA
Methamphetamine results in decreased expression of SFRP2 mRNA
CTD PMID:19564919 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Sgcz sarcoglycan zeta affects response to substance ISO SGCZ gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr16:53,660,283...54,740,811
Ensembl chr16:53,660,502...54,735,193
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SGK1 mRNA
Methamphetamine results in increased expression of SGK1 mRNA
CTD PMID:19564919 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 decreases expression ISO Methamphetamine results in decreased expression of SGK3 mRNA CTD PMID:26307267 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476
JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression ISO Methamphetamine results in decreased expression of SGMS1 mRNA CTD PMID:36914120 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603
JBrowse link
G Sh2d3c SH2 domain containing 3C increases expression ISO Methamphetamine results in increased expression of SH2D3C mRNA CTD PMID:26307267 NCBI chr 3:16,010,622...16,046,491
Ensembl chr 3:16,010,625...16,046,484
JBrowse link
G Sh3d19 SH3 domain containing 19 decreases expression EXP Methamphetamine results in decreased expression of SH3D19 mRNA CTD PMID:19564919 NCBI chr 2:171,356,244...171,516,042
Ensembl chr 2:171,356,251...171,515,561
JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 decreases expression EXP Methamphetamine results in decreased expression of SH3GL1 protein CTD PMID:19826936 NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716
JBrowse link
G Sh3gl2 SH3 domain containing GRB2 like 2, endophilin A1 decreases expression EXP
ISO
Methamphetamine results in decreased expression of SH3GL2 protein
Methamphetamine results in decreased expression of SH3GL2 mRNA
CTD PMID:19826936 PMID:26307267 NCBI chr 5:99,653,189...99,827,500
Ensembl chr 5:99,653,152...100,113,843
JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 affects response to substance ISO SH3RF3 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257
JBrowse link
G Sh3yl1 SH3 and SYLF domain containing 1 decreases expression ISO Methamphetamine results in decreased expression of SH3YL1 mRNA CTD PMID:26307267 NCBI chr 6:47,522,098...47,565,858
Ensembl chr 6:47,522,091...47,565,858
JBrowse link
G Shcbp1 SHC binding and spindle associated 1 decreases expression ISO
EXP
Methamphetamine results in decreased expression of SHCBP1 mRNA CTD PMID:25290377 PMID:28341135 NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844
JBrowse link
G Shf Src homology 2 domain containing F decreases expression ISO Methamphetamine results in decreased expression of SHF mRNA CTD PMID:26307267 NCBI chr 3:109,296,517...109,316,315
Ensembl chr 3:109,296,784...109,316,328
JBrowse link
G Shisa2 shisa family member 2 increases expression EXP Methamphetamine results in increased expression of SHISA2 mRNA CTD PMID:28341135 NCBI chr15:33,806,715...33,811,013
Ensembl chr15:33,805,958...33,811,013
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 increases expression EXP Methamphetamine results in increased expression of SIAH2 mRNA CTD PMID:19564919 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
JBrowse link
G Sidt2 SID1 transmembrane family, member 2 increases expression ISO Methamphetamine results in increased expression of SIDT2 mRNA CTD PMID:26307267 NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700
JBrowse link
G Sigirr single Ig and TIR domain containing multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SIGIRR mRNA
Methamphetamine results in decreased expression of SIGIRR mRNA
CTD PMID:19564919 NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269
JBrowse link
G Sik1 salt-inducible kinase 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SIK1 mRNA
Methamphetamine results in increased expression of SIK1 mRNA
CTD PMID:19564919 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Sirt1 sirtuin 1 increases expression EXP Methamphetamine results in increased expression of SIRT1 protein CTD PMID:35863504 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt2 sirtuin 2 decreases expression EXP Methamphetamine results in decreased expression of SIRT2 mRNA CTD PMID:25452209 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Sirt5 sirtuin 5 decreases expression EXP Methamphetamine results in decreased expression of SIRT5 mRNA CTD PMID:25452209 NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101
JBrowse link
G Sirt6 sirtuin 6 decreases expression EXP Methamphetamine results in decreased expression of SIRT6 mRNA CTD PMID:25452209 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Sirt7 sirtuin 7 increases expression
increases methylation
ISO Methamphetamine results in increased expression of SIRT7 mRNA
Methamphetamine results in increased methylation of SIRT7 promoter
CTD PMID:26307267 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172
JBrowse link
G Six4 SIX homeobox 4 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SIX4 mRNA
Methamphetamine results in decreased expression of SIX4 mRNA
CTD PMID:19564919 NCBI chr 6:91,802,328...91,816,002
Ensembl chr 6:91,802,329...91,815,992
JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 decreases expression EXP Methamphetamine results in decreased expression of SKA1 mRNA CTD PMID:28341135 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions
decreases expression
ISO (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of SLC10A1 mRNA] CTD PMID:11756511 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc12a3 solute carrier family 12 member 3 decreases expression ISO Methamphetamine results in decreased expression of SLC12A3 mRNA CTD PMID:26307267 NCBI chr19:10,630,651...10,679,250
Ensembl chr19:10,631,393...10,669,091
JBrowse link
G Slc12a9 solute carrier family 12, member 9 increases expression ISO Methamphetamine results in increased expression of SLC12A9 mRNA CTD PMID:26307267 NCBI chr12:19,368,990...19,385,881
Ensembl chr12:19,369,004...19,385,877
JBrowse link
G Slc14a2 solute carrier family 14 member 2 decreases expression ISO Methamphetamine results in decreased expression of SLC14A2 mRNA CTD PMID:26307267 NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968
JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression ISO Methamphetamine results in increased expression of SLC16A1 mRNA CTD PMID:36914120 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Slc16a11 solute carrier family 16, member 11 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of SLC16A11 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A11 mRNA
CTD PMID:19564919 NCBI chr10:54,929,129...54,933,021
Ensembl chr10:54,927,725...54,942,915
JBrowse link
G Slc16a13 solute carrier family 16, member 13 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of SLC16A13 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A13 mRNA
CTD PMID:19564919 NCBI chr10:54,925,973...54,937,860
Ensembl chr10:54,926,760...54,937,788
JBrowse link
G Slc17a1 solute carrier family 17 member 1 increases expression EXP Methamphetamine results in increased expression of SLC17A1 mRNA CTD PMID:15644446 NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304
JBrowse link
G Slc18a2 solute carrier family 18 member A2 decreases expression
decreases activity
multiple interactions
increases nitrosation
affects localization
decreases response to substance
affects response to substance
ISO
EXP
Methamphetamine results in decreased expression of SLC18A2 protein
Methamphetamine results in decreased activity of SLC18A2 protein
[rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]
S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased activity of SLC18A2 protein]; S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]
Methamphetamine results in increased nitrosation of SLC18A2 protein
Methamphetamine affects the localization of SLC18A2 protein
SLC18A2 protein results in decreased susceptibility to Methamphetamine
SLC18A2 protein affects the susceptibility to Methamphetamine
CTD PMID:12050851 PMID:16518646 PMID:16622715 PMID:17683483 PMID:17686046 More... NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression ISO
EXP
Methamphetamine results in increased expression of SLC1A2 mRNA CTD PMID:17105907 PMID:18419818 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc1a3 solute carrier family 1 member 3 increases expression EXP Methamphetamine results in increased expression of SLC1A3 mRNA CTD PMID:18419818 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
JBrowse link
G Slc22a13 solute carrier family 22 member 13 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC22A13 mRNA
Methamphetamine results in decreased expression of SLC22A13 mRNA
CTD PMID:19564919 NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions EXP Methamphetamine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:9830022 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc25a25 solute carrier family 25 member 25 increases expression EXP Methamphetamine results in increased expression of SLC25A25 mRNA CTD PMID:19564919 NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
JBrowse link
G Slc25a28 solute carrier family 25 member 28 increases expression ISO Methamphetamine results in increased expression of SLC25A28 mRNA CTD PMID:26307267 NCBI chr 1:242,530,877...242,542,140
Ensembl chr 1:242,530,899...242,542,115
JBrowse link
G Slc25a35 solute carrier family 25, member 35 decreases expression EXP Methamphetamine results in decreased expression of SLC25A35 mRNA CTD PMID:19564919 NCBI chr10:53,672,851...53,677,501
Ensembl chr10:53,673,340...53,698,160
JBrowse link
G Slc26a10 solute carrier family 26, member 10 increases expression ISO Methamphetamine results in increased expression of SLC26A10 mRNA CTD PMID:26307267 NCBI chr 7:62,995,165...63,005,099
Ensembl chr 7:62,995,381...63,004,087
JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression ISO Methamphetamine results in increased expression of SLC27A1 mRNA CTD PMID:26307267 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc29a3 solute carrier family 29 member 3 decreases expression EXP Methamphetamine results in decreased expression of SLC29A3 mRNA CTD PMID:19564919 NCBI chr20:28,645,265...28,685,388
Ensembl chr20:28,647,391...28,685,388
JBrowse link
G Slc2a12 solute carrier family 2 member 12 decreases expression ISO Methamphetamine results in decreased expression of SLC2A12 mRNA CTD PMID:26307267 NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971
JBrowse link
G Slc2a5 solute carrier family 2 member 5 increases expression ISO Methamphetamine results in increased expression of SLC2A5 protein CTD PMID:20110187 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc35b2 solute carrier family 35 member B2 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC35B2 mRNA
Methamphetamine results in decreased expression of SLC35B2 mRNA
CTD PMID:19564919 NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234
JBrowse link
G Slc38a3 solute carrier family 38, member 3 increases expression ISO Methamphetamine results in increased expression of SLC38A3 mRNA CTD PMID:36914120 NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988
JBrowse link
G Slc38a5 solute carrier family 38, member 5 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC38A5 mRNA
Methamphetamine results in decreased expression of SLC38A5 mRNA
CTD PMID:19564919 NCBI chr  X:14,213,727...14,222,498
Ensembl chr  X:14,213,729...14,222,498
JBrowse link
G Slc39a12 solute carrier family 39 member 12 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SLC39A12 mRNA
Methamphetamine results in increased expression of SLC39A12 mRNA
CTD PMID:19564919 NCBI chr17:77,353,761...77,440,384
Ensembl chr17:77,353,805...77,440,353
JBrowse link
G Slc39a3 solute carrier family 39 member 3 decreases expression EXP Methamphetamine results in decreased expression of SLC39A3 mRNA CTD PMID:19564919 NCBI chr 7:8,676,845...8,682,846
Ensembl chr 7:8,676,759...8,685,149
JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of SLC40A1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC40A1 mRNA
CTD PMID:19564919 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc4a3 solute carrier family 4 member 3 increases expression ISO Methamphetamine results in increased expression of SLC4A3 mRNA CTD PMID:26307267 NCBI chr 9:77,036,243...77,053,940
Ensembl chr 9:77,037,016...77,049,105
JBrowse link
G Slc5a3 solute carrier family 5 member 3 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SLC5A3 mRNA
Methamphetamine results in increased expression of SLC5A3 mRNA
CTD PMID:19564919 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Slc66a1 solute carrier family 66 member 1 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of SLC66A1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC66A1 mRNA
CTD PMID:19564919 NCBI chr 5:151,537,870...151,552,259
Ensembl chr 5:151,542,376...151,552,259
JBrowse link
G Slc6a13 solute carrier family 6 member 13 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC6A13 mRNA
Methamphetamine results in decreased expression of SLC6A13 mRNA
CTD PMID:19564919 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152
JBrowse link
G Slc6a2 solute carrier family 6 member 2 multiple interactions ISO Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein] CTD PMID:17234900 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
increases expression
decreases activity
decreases expression
affects response to substance
decreases response to substance
increases response to substance
affects abundance
ISO
EXP
indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Methylphenidate inhibits the reaction [SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]
Methamphetamine results in increased expression of SLC6A3 protein
Methamphetamine results in decreased activity of SLC6A3 protein
Methamphetamine results in decreased expression of SLC6A3 protein
SLC6A3 protein affects the susceptibility to Methamphetamine
Methamphetamine inhibits the reaction [(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester binds to SLC6A3 protein]; Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein]
SLC6A3 gene mutant form results in decreased susceptibility to Methamphetamine
Methamphetamine results in decreased expression of DAT protein; Methamphetamine results in decreased expression of SLC6A3; Methamphetamine results in decreased expression of SLC6A3 mRNA; Methamphetamine results in decreased expression of SLC6A3 protein
15-deoxyprostaglandin J2 inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; 6,7-dihydroxyflavone inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3]; 7-nitroindazole inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of DAT protein]; ANA 12 compound inhibits the reaction [6,7-dihydroxyflavone inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3]]; Enkephalin, Leucine-2-Alanine inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; estradiol 3-benzoate inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 mRNA]; estradiol 3-benzoate inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; FOS protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Ibuprofen inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; IFNG protein inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; IL6 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; isoliquiritigenin inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein]; Minocycline inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Naltrexone inhibits the reaction [Enkephalin, Leucine-2-Alanine inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]]; NOS1 protein affects the reaction [Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein]]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; NR4A2 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of DAT protein]; SLC6A3 protein affects the reaction [Methamphetamine affects the abundance of Dopamine]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP mRNA]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]
SLC6A3 3' UTR polymorphism results in increased susceptibility to Methamphetamine
SLC6A3 protein affects the abundance of Methamphetamine
CTD PMID:9132989 PMID:9634552 PMID:9763484 PMID:9765353 PMID:10559418 More... NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
increases response to substance
decreases expression
affects response to substance
affects expression
ISO
EXP
Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]
SLC6A4 protein results in increased susceptibility to Methamphetamine
Methamphetamine results in decreased expression of SLC6A4 protein
SLC6A4 mRNA affects the susceptibility to Methamphetamine
Methamphetamine affects the expression of SLC6A4 protein
IL6 protein affects the reaction [Methamphetamine affects the expression of SLC6A4 protein]; TRP53 protein affects the reaction [Methamphetamine affects the expression of SLC6A4 protein]
CTD PMID:9369336 PMID:10684896 PMID:11093760 PMID:15900317 PMID:16389202 More... NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Slc6a8 solute carrier family 6 member 8 increases expression EXP Methamphetamine results in increased expression of SLC6A8 mRNA CTD PMID:15644446 NCBI chr  X:151,384,675...151,393,979
Ensembl chr  X:151,384,675...151,393,979
JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases response to substance ISO SLC6A9 gene SNP results in increased susceptibility to Methamphetamine CTD PMID:17582620 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression EXP Methamphetamine results in increased expression of SLC7A11 mRNA CTD PMID:28619521 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression EXP Methamphetamine results in increased expression of SLC7A5 mRNA CTD PMID:32035215 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Slc9a8 solute carrier family 9 member A8 increases expression ISO Methamphetamine results in increased expression of SLC9A8 mRNA CTD PMID:26307267 NCBI chr 3:156,147,855...156,198,497
Ensembl chr 3:156,148,104...156,198,471
JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 increases expression EXP Methamphetamine results in increased expression of SLCO1C1 mRNA CTD PMID:32035215 NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression EXP Methamphetamine results in decreased expression of SLCO2B1 mRNA CTD PMID:19564919 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 increases expression ISO Methamphetamine results in increased expression of SLCO4C1 mRNA CTD PMID:25290377 NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715
JBrowse link
G Slk STE20-like kinase increases expression ISO Methamphetamine results in increased expression of SLK mRNA CTD PMID:26307267 NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530
JBrowse link
G Smad3 SMAD family member 3 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of SMAD3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of SMAD3 mRNA
CTD PMID:19564919 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 increases expression ISO Methamphetamine results in increased expression of SMARCD3 mRNA CTD PMID:26307267 NCBI chr 4:10,548,693...10,580,334
Ensembl chr 4:10,548,751...10,580,326
JBrowse link
G Smc3 structural maintenance of chromosomes 3 increases expression EXP Methamphetamine results in increased expression of SMC3 mRNA CTD PMID:15644446 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522
JBrowse link
G Smcp sperm mitochondria-associated cysteine-rich protein decreases expression ISO Methamphetamine results in decreased expression of SMCP mRNA CTD PMID:26307267 NCBI chr 2:178,160,948...178,165,951
Ensembl chr 2:178,160,127...178,166,001
JBrowse link
G Smoc2 SPARC related modular calcium binding 2 decreases expression ISO Methamphetamine results in decreased expression of SMOC2 mRNA CTD PMID:36914120 NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693
JBrowse link
G Smox spermine oxidase increases expression ISO Methamphetamine results in increased expression of SMOX mRNA CTD PMID:26307267 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 increases expression ISO Methamphetamine results in increased expression of SMPD4 mRNA CTD PMID:26307267 NCBI chr11:83,362,534...83,386,257
Ensembl chr11:83,362,534...83,386,250
JBrowse link
G Smyd3 SET and MYND domain containing 3 affects response to substance ISO SMYD3 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr13:90,709,263...91,266,209
Ensembl chr13:90,709,270...91,266,253
JBrowse link
G Snap29 synaptosome associated protein 29 increases expression EXP Methamphetamine results in increased expression of SNAP29 mRNA CTD PMID:34374793 NCBI chr11:83,578,479...83,608,953
Ensembl chr11:83,578,489...83,608,958
JBrowse link
G Snca synuclein alpha increases response to substance
affects localization
multiple interactions
increases expression
affects response to substance
ISO
EXP
SNCA gene SNP results in increased susceptibility to Methamphetamine
Methamphetamine affects the localization of SNCA protein modified form
SNCA protein results in increased susceptibility to Methamphetamine
[SNCA protein co-treated with Methamphetamine] results in decreased expression of NR4A2 protein; [SNCA protein co-treated with Methamphetamine] results in increased expression of IL1B protein; [SNCA protein co-treated with Methamphetamine] results in increased expression of IL6 protein; [SNCA protein co-treated with Methamphetamine] results in increased expression of NFKB1 protein; [SNCA protein co-treated with Methamphetamine] results in increased expression of TNF protein; MAPT protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of SNCA protein; SNCA gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of RBFOX3 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of CDK5 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GSK3B protein modified form]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MAPT protein modified form]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of SNCA protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of CNP protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of MBP protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of TFEB protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of SQSTM1 protein]; SNCA protein affects the reaction [Methamphetamine results in increased phosphorylation of MTOR protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased expression of SNCA protein]
PRKN protein inhibits the reaction [Methamphetamine results in increased expression of SNCA protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; TRIB3 protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]
CEBPB protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; Methamphetamine promotes the reaction [SNCA protein binds to SNCA protein]
SNCA affects the susceptibility to Methamphetamine
CTD PMID:12732244 PMID:15542733 PMID:16181420 PMID:17904249 PMID:25090657 More... NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sncb synuclein, beta increases expression EXP Methamphetamine results in increased expression of SNCB protein CTD PMID:19826936 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012
JBrowse link
G Snrk SNF related kinase increases expression
increases methylation
ISO Methamphetamine results in increased expression of SNRK mRNA
Methamphetamine results in increased methylation of SNRK promoter
CTD PMID:26307267 NCBI chr 8:121,779,704...121,833,949
Ensembl chr 8:121,793,302...121,832,323
JBrowse link
G Snta1 syntrophin, alpha 1 increases expression ISO Methamphetamine results in increased expression of SNTA1 mRNA CTD PMID:36914120 NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709
JBrowse link
G Snx27 sorting nexin 27 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of SNX27 mRNA alternative form; Methamphetamine results in increased expression of SNX27 protein
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of SNX27 mRNA alternative form]
CTD PMID:12740601 NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression EXP Methamphetamine results in increased expression of SOCS3 mRNA CTD PMID:15644446 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod1 superoxide dismutase 1 increases activity
multiple interactions
affects response to substance
affects expression
ISO
EXP
Methamphetamine results in increased activity of SOD1 protein
PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD1 protein]
ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of SOD1 protein]; SOD1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SOD1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein]
SOD1 protein affects the susceptibility to Methamphetamine
Methamphetamine affects the expression of SOD1 protein
CTD PMID:7505315 PMID:7530424 PMID:11158245 PMID:11457507 PMID:15189342 More... NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases response to substance
increases activity
multiple interactions
ISO SOD2 gene polymorphism results in increased susceptibility to Methamphetamine
Methamphetamine results in increased activity of SOD2 protein
PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD2 protein]
PRKCD affects the reaction [Methamphetamine results in increased activity of SOD2 protein]
CTD PMID:16807759 PMID:24430743 PMID:25523949 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 increases expression ISO Methamphetamine results in increased expression of SORBS1 mRNA CTD PMID:26307267 PMID:36914120 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169
JBrowse link
G Sorcs3 sortilin-related VPS10 domain containing receptor 3 increases expression EXP Methamphetamine results in increased expression of SORCS3 mRNA CTD PMID:19564919 NCBI chr 1:247,099,178...247,734,027
Ensembl chr 1:247,099,408...247,734,027
JBrowse link
G Sox17 SRY-box transcription factor 17 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX17 mRNA
Methamphetamine results in decreased expression of SOX17 mRNA
CTD PMID:19564919 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Sox18 SRY-box transcription factor 18 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX18 mRNA
Methamphetamine results in decreased expression of SOX18 mRNA
CTD PMID:19564919 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290
JBrowse link
G Sp100 SP100 nuclear antigen increases expression ISO Methamphetamine results in increased expression of SP100 mRNA CTD PMID:26307267 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
JBrowse link
G Spaca9 sperm acrosome associated 9 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SPACA9 mRNA
Methamphetamine results in decreased expression of SPACA9 mRNA
CTD PMID:19564919 NCBI chr 3:12,019,376...12,028,801
Ensembl chr 3:12,019,363...12,029,119
JBrowse link
G Spag1 sperm associated antigen 1 decreases expression EXP Methamphetamine results in decreased expression of SPAG1 mRNA CTD PMID:35863504 NCBI chr 7:67,361,474...67,421,369
Ensembl chr 7:67,361,477...67,421,368
JBrowse link
G Spag4 sperm associated antigen 4 decreases methylation ISO Methamphetamine results in decreased methylation of SPAG4 promoter CTD PMID:26307267 NCBI chr 3:144,581,006...144,587,879
Ensembl chr 3:144,581,095...144,585,435
JBrowse link
G Spag8 sperm associated antigen 8 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of SPAG8 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SPAG8 mRNA
CTD PMID:19564919 NCBI chr 5:57,901,681...57,903,894
Ensembl chr 5:57,901,682...57,903,894
JBrowse link
G Spag9 sperm associated antigen 9 increases expression EXP Methamphetamine results in increased expression of SPAG9 mRNA CTD PMID:19564919 NCBI chr10:78,943,439...79,077,797
Ensembl chr10:78,943,479...79,077,797
JBrowse link
G Sparc secreted protein acidic and cysteine rich decreases expression ISO Methamphetamine results in decreased expression of SPARC mRNA CTD PMID:36914120 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Spata6l spermatogenesis associated 6-like multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of SPATA6L mRNA
Methamphetamine results in decreased expression of SPATA6L mRNA
CTD PMID:19564919 NCBI chr 1:226,630,470...226,682,979
Ensembl chr 1:226,641,518...226,682,884
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex decreases expression EXP Methamphetamine results in decreased expression of SPC25 mRNA CTD PMID:28341135 NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
JBrowse link
G Speg striated muscle enriched protein kinase increases expression ISO Methamphetamine results in increased expression of SPEG mRNA CTD PMID:26307267 PMID:36914120 NCBI chr 9:76,865,714...76,923,170
Ensembl chr 9:76,865,754...76,923,144
JBrowse link
G Spmip11 sperm microtubule inner protein 11 increases expression EXP Methamphetamine results in increased expression of SPMIP11 mRNA CTD PMID:28341135 NCBI chr 7:129,720,950...129,742,485
Ensembl chr 7:129,720,950...129,742,485
JBrowse link
G Spock2 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 increases expression EXP Methamphetamine results in increased expression of SPOCK2 mRNA CTD PMID:32035215 NCBI chr20:28,037,334...28,064,272
Ensembl chr20:28,033,475...28,064,272
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 increases expression EXP Methamphetamine results in increased expression of SPRED1 mRNA CTD PMID:19564919 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases expression ISO Methamphetamine results in increased expression of SPTAN1 mRNA CTD PMID:26307267 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 decreases expression ISO Methamphetamine results in decreased expression of SPTY2D1 mRNA CTD PMID:26307267 NCBI chr 1:97,531,495...97,549,616
Ensembl chr 1:97,531,508...97,549,581
JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of SQSTM1 protein
SNCA protein affects the reaction [Methamphetamine results in increased expression of SQSTM1 protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein]
Lactulose promotes the reaction [Methamphetamine results in increased expression of SQSTM1 mRNA]; STX17 protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein]
Methamphetamine results in increased expression of SQSTM1 mRNA; Methamphetamine results in increased expression of SQSTM1 protein
CTD PMID:23933405 PMID:30450033 PMID:34374793 PMID:34562559 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srf serum response factor increases expression ISO Methamphetamine results in increased expression of SRF mRNA CTD PMID:36914120 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Srgap1 SLIT-ROBO Rho GTPase activating protein 1 decreases expression ISO Methamphetamine results in decreased expression of SRGAP1 mRNA CTD PMID:26307267 NCBI chr 7:57,329,532...57,594,681
Ensembl chr 7:57,329,532...57,596,196
JBrowse link
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 increases methylation
increases expression
ISO Methamphetamine results in increased methylation of SRGAP2 promoter
Methamphetamine results in increased expression of SRGAP2 mRNA
CTD PMID:26307267 NCBI chr13:42,745,956...42,967,091
Ensembl chr13:42,745,947...42,967,058
JBrowse link
G Srpk3 SRSF protein kinase 3 increases expression ISO Methamphetamine results in increased expression of SRPK3 mRNA CTD PMID:26307267 NCBI chr  X:151,510,452...151,515,208
Ensembl chr  X:151,510,539...151,515,198
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked decreases expression EXP Methamphetamine results in decreased expression of SRPX mRNA CTD PMID:15644446 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882
JBrowse link
G Srrm1 serine and arginine repetitive matrix 1 increases expression ISO Methamphetamine results in increased expression of SRRM1 mRNA CTD PMID:26307267 NCBI chr 5:147,559,515...147,591,895
Ensembl chr 5:147,559,514...147,591,849
JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 increases expression ISO Methamphetamine results in increased expression of SRRM2 mRNA CTD PMID:26307267 NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751
JBrowse link
G Srrt serrate, RNA effector molecule increases expression
decreases methylation
ISO Methamphetamine results in increased expression of SRRT mRNA
Methamphetamine results in decreased methylation of SRRT promoter
CTD PMID:26307267 NCBI chr12:19,392,578...19,406,098
Ensembl chr12:19,392,625...19,406,095
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 decreases expression ISO Methamphetamine results in decreased expression of SRSF5 mRNA CTD PMID:36914120 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
JBrowse link
G Sstr2 somatostatin receptor 2 increases expression EXP Methamphetamine results in increased expression of SSTR2 mRNA CTD PMID:19564919 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
JBrowse link
G St13 ST13, Hsp70 interacting protein increases expression
multiple interactions
EXP Methamphetamine results in increased expression of ST13 mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ST13 mRNA]
CTD PMID:19149911 PMID:19564919 NCBI chr 7:112,891,007...112,925,727
Ensembl chr 7:112,844,375...112,925,945
JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 increases expression ISO Methamphetamine results in increased expression of ST3GAL1 mRNA CTD PMID:26307267 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236
JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 increases expression ISO Methamphetamine results in increased expression of ST3GAL5 mRNA CTD PMID:36914120 NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558
JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ST8SIA6 mRNA
Methamphetamine results in decreased expression of ST8SIA6 mRNA
CTD PMID:19564919 NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299
JBrowse link
G Stat6 signal transducer and activator of transcription 6 decreases expression EXP Methamphetamine results in decreased expression of STAT6 mRNA CTD PMID:15644446 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Stc2 stanniocalcin 2 increases expression EXP Methamphetamine results in increased expression of STC2 mRNA CTD PMID:28619521 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Steap1 STEAP family member 1 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of STEAP1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of STEAP1 mRNA
CTD PMID:19564919 NCBI chr 4:28,276,972...28,287,484
Ensembl chr 4:28,276,909...28,287,479
JBrowse link
G Stim1 stromal interaction molecule 1 increases expression ISO Methamphetamine results in increased expression of STIM1 mRNA CTD PMID:26307267 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression
increases expression
EXP Methamphetamine results in decreased expression of STIP1 protein
Methamphetamine results in increased expression of STIP1 mRNA
CTD PMID:19149911 PMID:19564919 PMID:19826936 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Stk11ip serine/threonine kinase 11 interacting protein increases expression ISO Methamphetamine results in increased expression of STK11IP mRNA CTD PMID:26307267 NCBI chr 9:77,012,297...77,027,989
Ensembl chr 9:77,012,693...77,027,873
JBrowse link
G Stmn1 stathmin 1 affects expression EXP Methamphetamine affects the expression of STMN1 protein CTD PMID:17904249 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Stpg1 sperm-tail PG-rich repeat containing 1 increases methylation ISO Methamphetamine results in increased methylation of STPG1 promoter CTD PMID:26307267 NCBI chr 5:147,717,084...147,769,792
Ensembl chr 5:147,726,646...147,769,788
JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 decreases expression EXP Methamphetamine results in decreased expression of STRA6 mRNA CTD PMID:19564919 NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860
JBrowse link
G Strada STE20 related adaptor alpha decreases expression EXP Methamphetamine results in decreased expression of STRADA mRNA CTD PMID:19564919 NCBI chr10:91,094,849...91,123,890
Ensembl chr10:91,094,687...91,123,830
JBrowse link
G Stx17 syntaxin 17 decreases expression
multiple interactions
EXP
ISO
Methamphetamine results in decreased expression of STX17 mRNA; Methamphetamine results in decreased expression of STX17 protein
STX17 protein inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased lipidation of MAP1LC3B protein]
CTD PMID:34374793 PMID:35643125 NCBI chr 5:62,446,138...62,506,108
Ensembl chr 5:62,446,187...62,504,451
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 decreases expression ISO Methamphetamine results in decreased expression of STYXL1 mRNA CTD PMID:26307267 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases expression EXP Methamphetamine results in increased expression of SULT1A1 mRNA; Methamphetamine results in increased expression of SULT1A1 protein CTD PMID:23026138 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP Methamphetamine results in increased expression of SULT2A1 mRNA; Methamphetamine results in increased expression of SULT2A1 protein CTD PMID:23026138 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit increases expression ISO Methamphetamine results in increased expression of SUPT5H mRNA CTD PMID:26307267 NCBI chr 1:83,586,713...83,616,971
Ensembl chr 1:83,586,718...83,616,892
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor increases expression ISO Methamphetamine results in increased expression of SUPT6H mRNA CTD PMID:26307267 NCBI chr10:63,103,920...63,140,780
Ensembl chr10:63,103,921...63,140,780
JBrowse link
G Sv2c synaptic vesicle glycoprotein 2c multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SV2C mRNA
Methamphetamine results in increased expression of SV2C mRNA
CTD PMID:19564919 NCBI chr 2:27,232,933...27,428,479
Ensembl chr 2:27,232,933...27,428,477
JBrowse link
G Svil supervillin increases expression ISO Methamphetamine results in increased expression of SVIL mRNA CTD PMID:26307267 NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404
JBrowse link
G Swt1 SWT1 RNA endoribonuclease homolog multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of SWT1 mRNA
Methamphetamine results in increased expression of SWT1 mRNA
CTD PMID:19564919 NCBI chr13:63,452,494...63,509,982
Ensembl chr13:63,452,496...63,509,980
JBrowse link
G Syn1 synapsin I decreases expression ISO Methamphetamine results in decreased expression of SYN1 protein CTD PMID:34461196 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396
JBrowse link
G Syn2 synapsin II increases expression EXP Methamphetamine results in increased expression of SYN2 protein CTD PMID:19826936 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 increases expression ISO Methamphetamine results in increased expression of SYNE1 mRNA CTD PMID:26307267 NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322
JBrowse link
G Synj2 synaptojanin 2 increases expression ISO Methamphetamine results in increased expression of SYNJ2 mRNA CTD PMID:26307267 NCBI chr 1:46,518,594...46,621,919
Ensembl chr 1:46,518,709...46,633,687
JBrowse link
G Syp synaptophysin decreases expression
increases expression
multiple interactions
EXP
ISO
Methamphetamine results in decreased expression of SYP protein
Methamphetamine results in increased expression of SYP protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of SYP protein]; Melatonin inhibits the reaction [Methamphetamine results in decreased expression of SYP protein]
CTD PMID:14657756 PMID:19409439 PMID:33421459 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Syt10 synaptotagmin 10 decreases expression
increases expression
ISO
EXP
Methamphetamine results in decreased expression of SYT10 mRNA
Methamphetamine results in increased expression of SYT10 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr 7:120,857,698...120,920,863
Ensembl chr 7:120,862,972...120,920,863
JBrowse link
G Syt17 synaptotagmin 17 increases methylation ISO Methamphetamine results in increased methylation of SYT17 promoter CTD PMID:26307267 NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:172,696,120...172,761,960
JBrowse link
G Syt2 synaptotagmin 2 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] affects the expression of SYT2 mRNA
Methamphetamine results in decreased expression of SYT2 mRNA
CTD PMID:19564919 NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859
JBrowse link
G Syt3 synaptotagmin 3 decreases expression EXP Methamphetamine results in decreased expression of SYT3 mRNA CTD PMID:19564919 NCBI chr 1:94,880,835...94,895,518
Ensembl chr 1:94,881,247...94,895,246
JBrowse link
G Syt9 synaptotagmin 9 decreases expression ISO Methamphetamine results in decreased expression of SYT9 mRNA CTD PMID:26307267 NCBI chr 1:161,275,882...161,456,384
Ensembl chr 1:161,275,734...161,455,007
JBrowse link
G Taar1 trace-amine-associated receptor 1 multiple interactions
affects response to substance
ISO Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Methylphenidate inhibits the reaction [SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]; SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]; SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]
TAAR1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; TAAR1 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]
TAAR1 protein affects the susceptibility to Methamphetamine
CTD PMID:17234900 PMID:28919515 NCBI chr 1:21,517,742...21,518,740
Ensembl chr 1:21,517,258...21,532,084
JBrowse link
G Tac1 tachykinin, precursor 1 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of TAC1 mRNA
ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 mRNA]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 mRNA]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of TAC1 mRNA]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]
Methamphetamine results in increased expression of TAC1 mRNA; Methamphetamine results in increased expression of TAC1 protein modified form
CTD PMID:15644446 PMID:29467000 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 increases expression ISO Methamphetamine results in increased expression of TACC2 mRNA CTD PMID:26307267 PMID:36914120 NCBI chr 1:185,139,223...185,327,881
Ensembl chr 1:185,116,111...185,327,881
JBrowse link
G Tada1 transcriptional adaptor 1 increases methylation ISO Methamphetamine results in increased methylation of TADA1 promoter CTD PMID:26307267 NCBI chr13:78,632,908...78,646,863
Ensembl chr13:78,632,866...78,647,504
JBrowse link
G Taf15 TATA-box binding protein associated factor 15 increases expression ISO Methamphetamine results in increased expression of TAF15 mRNA CTD PMID:26307267 NCBI chr10:68,272,921...68,304,951
Ensembl chr10:68,272,969...68,304,949
JBrowse link
G Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C affects methylation
increases expression
ISO Methamphetamine affects the methylation of TAF1C promoter
Methamphetamine results in increased expression of TAF1C mRNA
CTD PMID:26307267 NCBI chr19:47,652,451...47,658,971
Ensembl chr19:47,652,452...47,658,971
JBrowse link
G Tafa5 TAFA chemokine like family member 5 decreases expression ISO Methamphetamine results in decreased expression of TAFA5 mRNA CTD PMID:26307267 NCBI chr 7:118,613,731...118,835,016
Ensembl chr 7:118,613,889...118,834,353
JBrowse link
G Tagln3 transgelin 3 increases expression EXP Methamphetamine results in increased expression of TAGLN3 protein CTD PMID:19826936 NCBI chr11:55,099,887...55,113,457
Ensembl chr11:55,099,743...55,113,485
JBrowse link
G Taok2 TAO kinase 2 increases expression ISO Methamphetamine results in increased expression of TAOK2 mRNA CTD PMID:26307267 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613
JBrowse link
G Tarbp2 Tarbp2 subunit of RISC loading complex increases expression ISO Methamphetamine results in increased expression of TARBP2 mRNA CTD PMID:26307267 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314
JBrowse link
G Tas1r1 taste 1 receptor member 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TAS1R1 mRNA
Methamphetamine results in decreased expression of TAS1R1 mRNA
CTD PMID:19564919 NCBI chr 5:162,533,838...162,546,408
Ensembl chr 5:162,533,841...162,545,562
JBrowse link
G Tas2r119 taste receptor, type 2, member 119 increases expression EXP Methamphetamine results in increased expression of TAS2R119 mRNA CTD PMID:15644446 NCBI chr 2:83,237,595...83,238,602
Ensembl chr 2:83,237,595...83,238,602
JBrowse link
G Tbc1d4 TBC1 domain family, member 4 increases expression ISO Methamphetamine results in increased expression of TBC1D4 mRNA CTD PMID:26307267 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
JBrowse link
G Tcap titin-cap decreases expression ISO Methamphetamine results in decreased expression of TCAP mRNA CTD PMID:36914120 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887
JBrowse link
G Tcf15 transcription factor 15 increases expression ISO Methamphetamine results in increased expression of TCF15 mRNA CTD PMID:36914120 NCBI chr 3:140,638,984...140,644,766
Ensembl chr 3:140,638,984...140,644,766
JBrowse link
G Tcf4 transcription factor 4 increases expression ISO Methamphetamine results in increased expression of TCF4 mRNA CTD PMID:26307267 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
JBrowse link
G Tdh L-threonine dehydrogenase decreases expression EXP Methamphetamine results in decreased expression of TDH mRNA CTD PMID:19564919 NCBI chr15:37,739,823...37,753,365
Ensembl chr15:37,739,823...37,753,365
JBrowse link
G Tdrp testis development related protein decreases expression EXP Methamphetamine results in decreased expression of TDRP mRNA CTD PMID:19564919 NCBI chr16:75,624,047...75,652,635
Ensembl chr16:75,624,907...75,652,420
JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 increases expression ISO Methamphetamine results in increased expression of TECPR1 mRNA CTD PMID:26307267 NCBI chr12:10,391,587...10,420,462
Ensembl chr12:10,391,696...10,419,611
JBrowse link
G Tecrl trans-2,3-enoyl-CoA reductase-like increases expression ISO Methamphetamine results in increased expression of TECRL mRNA CTD PMID:36914120 NCBI chr14:24,732,241...24,805,272
Ensembl chr14:24,732,241...24,805,272
JBrowse link
G Tecta tectorin alpha multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TECTA mRNA
Methamphetamine results in decreased expression of TECTA mRNA
CTD PMID:19564919 NCBI chr 8:42,707,962...42,779,726
Ensembl chr 8:42,707,962...42,779,707
JBrowse link
G Tef TEF transcription factor, PAR bZIP family member increases expression ISO Methamphetamine results in increased expression of TEF mRNA CTD PMID:26307267 NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783
JBrowse link
G Tekt1 tektin 1 decreases expression ISO Methamphetamine results in decreased expression of TEKT1 mRNA CTD PMID:26307267 NCBI chr10:56,952,164...56,980,572
Ensembl chr10:56,952,167...56,980,572
JBrowse link
G Tent5a terminal nucleotidyltransferase 5A multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of TENT5A mRNA
Methamphetamine results in increased expression of TENT5A mRNA
CTD PMID:19564919 NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045
JBrowse link
G Terf1 telomeric repeat binding factor 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TERF1 mRNA
Methamphetamine results in decreased expression of TERF1 mRNA
CTD PMID:19564919 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Tex13b testis expressed 13B increases expression EXP Methamphetamine results in increased expression of TEX13B mRNA CTD PMID:28341135 NCBI chr  X:104,490,937...104,511,224
Ensembl chr  X:104,490,091...104,494,201
JBrowse link
G Tex28 testis expressed 28 decreases expression ISO Methamphetamine results in decreased expression of TEX28 mRNA CTD PMID:26307267 NCBI chr  X:151,922,210...151,955,902
Ensembl chr  X:151,925,526...151,954,567
JBrowse link
G Tfap2a transcription factor AP-2 alpha increases expression EXP Methamphetamine results in increased expression of TFAP2A mRNA CTD PMID:28341135 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tfeb transcription factor EB multiple interactions
decreases expression
ISO SNCA protein affects the reaction [Methamphetamine results in decreased expression of TFEB protein]; TFEB protein inhibits the reaction [Methamphetamine results in decreased expression of CNP protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased expression of SNCA protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased phosphorylation of MTOR protein] CTD PMID:34562559 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO
EXP
Methamphetamine results in increased expression of TGFB1 mRNA
Methamphetamine results in increased expression of TGFB1 protein
CTD PMID:12766323 PMID:35863504 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions
increases expression
EXP
ISO
GATA4 protein affects the reaction [Methamphetamine results in increased expression of TGFB2 mRNA] CTD PMID:36914120 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression ISO Methamphetamine results in increased expression of TGFBR1 mRNA CTD PMID:12766323 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression EXP
ISO
Methamphetamine results in increased expression of TGFBR2 mRNA CTD PMID:12766323 PMID:15644446 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Th tyrosine hydroxylase decreases expression
multiple interactions
decreases activity
affects expression
affects response to substance
ISO
EXP
Methamphetamine results in decreased expression of TH protein
ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; Methamphetamine results in decreased expression of and results in decreased activity of TH protein; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]
Methamphetamine results in decreased expression of TH mRNA; Methamphetamine results in decreased expression of TH protein
Methamphetamine results in decreased activity of TH protein
Methamphetamine affects the expression of TH mRNA
diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; Lithium inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; Melatonin inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; olanzapine inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of TH protein]
TH protein affects the susceptibility to Methamphetamine
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]]; 7-nitroindazole affects the reaction [Methamphetamine results in decreased expression of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased activity of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; [TH protein affects the abundance of Dopamine] which affects the susceptibility to Methamphetamine; [TH protein affects the chemical synthesis of Dopamine] which affects the susceptibility to Methamphetamine; Caffeine promotes the reaction [Methamphetamine results in decreased activity of TH protein]; Chlormethiazole inhibits the reaction [Methamphetamine results in decreased activity of TH protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]; GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; Methamphetamine results in decreased expression of and results in decreased activity of TH protein; Methamphetamine results in decreased expression of and results in increased phosphorylation of TH protein; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]; NR4A2 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; OPRM1 protein affects the susceptibility to [Methamphetamine results in decreased expression of TH mRNA]; OPRM1 protein affects the susceptibility to [Methamphetamine results in decreased expression of TH protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]; Phencyclidine inhibits the reaction [Methamphetamine results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; Raclopride inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; TAAR1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; talipexole inhibits the reaction [Methamphetamine results in decreased activity of TH protein]
CTD PMID:1381816 PMID:2579200 PMID:7996441 PMID:8931477 PMID:9655613 More... NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thada THADA, armadillo repeat containing decreases expression EXP Methamphetamine results in decreased expression of THADA mRNA CTD PMID:19564919 NCBI chr 6:10,183,942...10,488,007
Ensembl chr 6:10,183,982...10,487,159
JBrowse link
G Thbs3 thrombospondin 3 increases expression EXP Methamphetamine results in increased expression of THBS3 mRNA CTD PMID:35863504 NCBI chr 2:174,621,788...174,633,594
Ensembl chr 2:174,621,812...174,633,594
JBrowse link
G Thpo thrombopoietin increases expression ISO Methamphetamine results in increased expression of THPO mRNA CTD PMID:25290377 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Thra thyroid hormone receptor alpha decreases expression EXP Methamphetamine results in decreased expression of THRA mRNA CTD PMID:35301009 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thsd1 thrombospondin type 1 domain containing 1 increases expression
decreases expression
ISO
EXP
Methamphetamine results in increased expression of THSD1 mRNA
Methamphetamine results in decreased expression of THSD1 mRNA
CTD PMID:19564919 PMID:26307267 NCBI chr16:69,771,408...69,804,844
Ensembl chr16:69,771,408...69,801,504
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 increases expression
multiple interactions
ISO Methamphetamine results in increased expression of TICAM1 protein
TICAM1 protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; TICAM1 protein promotes the reaction [Methamphetamine results in increased expression of IL6 protein]
CTD PMID:32768653 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TIE1 mRNA
Methamphetamine results in decreased expression of TIE1 mRNA
CTD PMID:19564919 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO Methamphetamine results in increased expression of TIGAR mRNA CTD PMID:36914120 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b decreases expression EXP Methamphetamine results in decreased expression of TIMM17B mRNA CTD PMID:19149911 NCBI chr  X:14,596,330...14,603,491
Ensembl chr  X:14,594,577...14,603,416
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Methamphetamine results in increased expression of TIMP1 mRNA CTD PMID:19564919 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 decreases response to substance
increases activity
ISO TIMP2 protein results in decreased susceptibility to Methamphetamine
Methamphetamine results in increased activity of TIMP2 protein
CTD PMID:18198472 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 decreases expression ISO Methamphetamine results in decreased expression of TIMP4 mRNA CTD PMID:36914120 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
JBrowse link
G Tjap1 tight junction associated protein 1 increases expression ISO Methamphetamine results in increased expression of TJAP1 mRNA CTD PMID:26307267 NCBI chr 9:14,701,418...14,725,623
Ensembl chr 9:14,701,468...14,725,751
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
ISO [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of TJP1 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of TJP1 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TJP1 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TJP1 protein]
Methamphetamine results in decreased expression of TJP1 mRNA; Methamphetamine results in decreased expression of TJP1 protein
CTD PMID:35390362 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tk2 thymidine kinase 2 increases expression EXP Methamphetamine results in increased expression of TK2 mRNA CTD PMID:19149911 NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924
JBrowse link
G Tlcd3b TLC domain containing 3B increases expression ISO Methamphetamine results in increased expression of TLCD3B mRNA CTD PMID:26307267 NCBI chr 1:181,421,104...181,439,744
Ensembl chr 1:181,422,830...181,439,743
JBrowse link
G Tle2 TLE family member 2, transcriptional corepressor increases expression ISO Methamphetamine results in increased expression of TLE2 mRNA CTD PMID:26307267 NCBI chr 7:8,119,049...8,135,385
Ensembl chr 7:8,119,053...8,134,306
JBrowse link
G Tle3 TLE family member 3, transcriptional corepressor increases expression EXP
ISO
Methamphetamine results in increased expression of TLE3 mRNA CTD PMID:15644446 PMID:26307267 NCBI chr 8:61,857,791...61,903,505
Ensembl chr 8:61,858,200...61,903,493
JBrowse link
G Tlr1 toll-like receptor 1 increases expression ISO Methamphetamine results in increased expression of TLR1 mRNA CTD PMID:32768653 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
JBrowse link
G Tlr11 toll-like receptor 11 increases expression ISO Methamphetamine results in increased expression of TLR11 mRNA CTD PMID:32768653 NCBI chr15:23,545,408...23,549,849
Ensembl chr15:23,545,408...23,549,849
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions
increases expression
decreases expression
EXP
ISO
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TLR2 mRNA
Methamphetamine results in increased expression of TLR2 mRNA
Methamphetamine results in decreased expression of TLR2 mRNA
CTD PMID:19564919 PMID:32768653 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr3 toll-like receptor 3 increases expression ISO Methamphetamine results in increased expression of TLR3 mRNA CTD PMID:32768653 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tlr4 toll-like receptor 4 increases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of TLR4 protein
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TLR4 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TLR4 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of TLR4 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TJP1 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TJP1 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of IL1B protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TRAF6 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein]
Methamphetamine results in increased expression of TLR4 mRNA; Methamphetamine results in increased expression of TLR4 protein
Lactulose inhibits the reaction [Methamphetamine results in increased expression of TLR4 protein]
CTD PMID:30450033 PMID:32768653 PMID:33359793 PMID:35390362 PMID:35688268 More... NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr5 toll-like receptor 5 increases expression ISO Methamphetamine results in increased expression of TLR5 mRNA CTD PMID:32768653 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738
JBrowse link
G Tlr6 toll-like receptor 6 increases expression ISO Methamphetamine results in increased expression of TLR6 mRNA CTD PMID:32768653 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Tlr7 toll-like receptor 7 increases expression ISO Methamphetamine results in increased expression of TLR7 mRNA CTD PMID:32768653 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754
JBrowse link
G Tlr8 toll-like receptor 8 increases expression ISO Methamphetamine results in increased expression of TLR8 mRNA CTD PMID:32768653 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tlr9 toll-like receptor 9 decreases expression ISO Methamphetamine results in decreased expression of TLR9 mRNA CTD PMID:32768653 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tmc6 transmembrane channel like 6 decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of TMC6 promoter
Methamphetamine results in increased expression of TMC6 mRNA
CTD PMID:26307267 NCBI chr10:102,982,059...102,999,509
Ensembl chr10:102,971,229...102,998,960
JBrowse link
G Tmem123 transmembrane protein 123 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM123 mRNA
Methamphetamine results in decreased expression of TMEM123 mRNA
CTD PMID:19564919 NCBI chr 8:4,922,077...4,952,228
Ensembl chr 8:4,922,098...4,952,224
JBrowse link
G Tmem125 transmembrane protein 125 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of TMEM125 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM125 mRNA
CTD PMID:19564919 NCBI chr 5:132,063,162...132,064,566
Ensembl chr 5:132,059,554...132,079,297
Ensembl chr 5:132,059,554...132,079,297
JBrowse link
G Tmem150a transmembrane protein 150A decreases expression EXP Methamphetamine results in decreased expression of TMEM150A mRNA CTD PMID:19564919 NCBI chr 4:104,410,271...104,414,630
Ensembl chr 4:104,410,516...104,429,349
JBrowse link
G Tmem154 transmembrane protein 154 decreases expression ISO Methamphetamine results in decreased expression of TMEM154 mRNA CTD PMID:26307267 NCBI chr 2:170,015,247...170,054,903
Ensembl chr 2:170,015,184...170,052,481
JBrowse link
G Tmem177 transmembrane protein 177 decreases expression EXP Methamphetamine results in decreased expression of TMEM177 mRNA CTD PMID:19564919 NCBI chr13:31,023,893...31,027,368
Ensembl chr13:31,023,455...31,027,378
JBrowse link
G Tmem18 transmembrane protein 18 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of TMEM18 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM18 mRNA
CTD PMID:19564919 NCBI chr 6:47,206,845...47,214,294
Ensembl chr 6:47,206,845...47,214,294
JBrowse link
G Tmem252 transmembrane protein 252 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of TMEM252 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of TMEM252 mRNA
CTD PMID:19564919 NCBI chr 1:222,316,982...222,321,946
Ensembl chr 1:222,316,795...222,321,943
JBrowse link
G Tmem255b transmembrane protein 255B increases expression ISO Methamphetamine results in increased expression of TMEM255B mRNA CTD PMID:26307267 NCBI chr16:76,079,840...76,108,179
Ensembl chr16:76,079,845...76,106,795
JBrowse link
G Tmem259 transmembrane protein 259 increases expression ISO Methamphetamine results in increased expression of TMEM259 mRNA CTD PMID:26307267 NCBI chr 7:9,724,196...9,730,932
Ensembl chr 7:9,722,485...9,730,932
JBrowse link
G Tmem63a transmembrane protein 63a decreases expression EXP Methamphetamine results in decreased expression of TMEM63A mRNA CTD PMID:19564919 NCBI chr13:92,662,872...92,696,186
Ensembl chr13:92,663,968...92,696,183
JBrowse link
G Tmem91 transmembrane protein 91 decreases expression EXP Methamphetamine results in decreased expression of TMEM91 mRNA CTD PMID:32035215 NCBI chr 1:81,179,483...81,187,005
Ensembl chr 1:81,179,156...81,185,164
JBrowse link
G Tmem94 transmembrane protein 94 increases expression ISO Methamphetamine results in increased expression of TMEM94 mRNA CTD PMID:26307267 NCBI chr10:100,991,523...101,027,046
Ensembl chr10:100,991,573...101,027,394
JBrowse link
G Tmsb10 thymosin, beta 10 decreases expression ISO Methamphetamine results in decreased expression of TMSB10 mRNA CTD PMID:36914120 NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028
JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 increases expression
multiple interactions
EXP Methamphetamine results in increased expression of TMTC3 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TMTC3 mRNA
CTD PMID:19564919 NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385
JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 increases expression EXP Methamphetamine results in increased expression of TMX1 mRNA CTD PMID:19564919 NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
increases response to substance
affects response to substance
ISO
EXP
luzindole inhibits the reaction [Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; MTNR1B protein promotes the reaction [Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]]; TNF protein inhibits the reaction [Methamphetamine results in decreased uptake of Dopamine]; TNF protein inhibits the reaction [Methamphetamine results in increased secretion of Dopamine]
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of and results in increased secretion of TNF protein]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; [SNCA protein co-treated with Methamphetamine] results in increased expression of TNF protein; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]; Methamphetamine results in increased expression of and results in increased secretion of TNF protein; Minocycline inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of TNF protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]
Methamphetamine results in increased expression of TNF mRNA; Methamphetamine results in increased expression of TNF protein
TNF protein results in increased susceptibility to Methamphetamine
Lactulose inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; margatoxin inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; Metformin inhibits the reaction [Methamphetamine results in increased expression of TNF protein]
TNF protein affects the susceptibility to Methamphetamine
CTD PMID:11746378 PMID:12230306 PMID:14999072 PMID:16828290 PMID:20374443 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 decreases expression ISO Methamphetamine results in decreased expression of TNFAIP6 mRNA CTD PMID:26307267 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression EXP Methamphetamine results in increased expression of TNFRSF12A mRNA CTD PMID:19564919 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tnni1 troponin I1, slow skeletal type increases expression EXP Methamphetamine results in increased expression of TNNI1 mRNA CTD PMID:15644446 NCBI chr13:47,229,217...47,241,640
Ensembl chr13:47,229,216...47,241,644
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO
EXP
Methamphetamine results in increased expression of TNNI3 protein CTD PMID:16338525 PMID:35863504 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tnpo1 transportin 1 increases expression EXP Methamphetamine results in increased expression of TNPO1 mRNA CTD PMID:19564919 NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
JBrowse link
G Tnrc6a trinucleotide repeat containing adaptor 6A increases expression ISO Methamphetamine results in increased expression of TNRC6A mRNA CTD PMID:26307267 NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660
JBrowse link
G Tns1 tensin 1 increases expression ISO Methamphetamine results in increased expression of TNS1 mRNA CTD PMID:26307267 NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225
JBrowse link
G Tns2 tensin 2 increases expression ISO Methamphetamine results in increased expression of TNS2 mRNA CTD PMID:26307267 NCBI chr 7:133,229,746...133,247,889
Ensembl chr 7:133,206,364...133,247,888
JBrowse link
G Tob2 transducer of ERBB2, 2 decreases expression ISO Methamphetamine results in decreased expression of TOB2 mRNA CTD PMID:36914120 NCBI chr 7:113,362,703...113,371,423
Ensembl chr 7:113,361,148...113,372,688
JBrowse link
G Toe1 target of EGR1, exonuclease decreases expression EXP Methamphetamine results in decreased expression of TOE1 mRNA CTD PMID:19564919 NCBI chr 5:130,270,484...130,274,050
Ensembl chr 5:130,262,319...130,274,050
JBrowse link
G Tomm20l translocase of outer mitochondrial membrane 20 like decreases expression ISO Methamphetamine results in decreased expression of TOMM20L mRNA CTD PMID:26307267 NCBI chr 6:89,594,016...89,612,070
Ensembl chr 6:89,599,873...89,610,147
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO
EXP
Methamphetamine results in decreased expression of TOP2A mRNA
Methamphetamine results in decreased expression of TOP2A mRNA; Methamphetamine results in decreased expression of TOP2A protein
CTD PMID:25290377 PMID:28341135 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
affects response to substance
ISO
EXP
Methamphetamine results in increased expression of TRP53 protein; Methamphetamine results in increased expression of TRP53 protein modified form
Luteolin inhibits the reaction [Methamphetamine results in increased expression of TP53 protein]
TRP53 protein affects the susceptibility to Methamphetamine
NOS1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein]; SOD1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein]; TRP53 protein affects the reaction [Methamphetamine affects the expression of SLC6A4 protein]
CTD PMID:9369336 PMID:11457507 PMID:12050851 PMID:17234339 PMID:32035215 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 increases expression ISO Methamphetamine results in increased expression of TRP53I11 mRNA CTD PMID:26307267 NCBI chr 3:79,144,824...79,160,056
Ensembl chr 3:79,144,895...79,160,050
JBrowse link
G Tph2 tryptophan hydroxylase 2 affects response to substance ISO TPH2 protein affects the susceptibility to Methamphetamine CTD PMID:20722968 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424
JBrowse link
G Tpi1 triosephosphate isomerase 1 affects expression EXP Methamphetamine affects the expression of TPI1 protein CTD PMID:19826936 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases methylation ISO Methamphetamine results in decreased methylation of TPX2 promoter CTD PMID:26307267 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions
increases expression
EXP
ISO
Lactulose inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein]
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TRAF6 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TRAF6 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein]
Methamphetamine results in increased expression of TRAF6 mRNA; Methamphetamine results in increased expression of TRAF6 protein
CTD PMID:30450033 PMID:35390362 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Trappc12 trafficking protein particle complex subunit 12 decreases expression ISO Methamphetamine results in decreased expression of TRAPPC12 mRNA CTD PMID:26307267 NCBI chr 6:45,321,496...45,386,967
Ensembl chr 6:45,321,497...45,386,952
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 decreases expression
increases expression
EXP
ISO
Methamphetamine results in decreased expression of TREM2 mRNA
Methamphetamine results in increased expression of TREM2 mRNA; Methamphetamine results in increased expression of TREM2 protein
CTD PMID:19564919 PMID:35643125 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions
increases expression
ISO
EXP
CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]; TRIB3 protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; TRIB3 protein affects the reaction [Methamphetamine results in increased expression of SNCA protein] CTD PMID:31059759 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trim63 tripartite motif containing 63 increases expression ISO Methamphetamine results in increased expression of TRIM63 mRNA CTD PMID:23933405 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322
JBrowse link
G Trim67 tripartite motif-containing 67 decreases expression ISO Methamphetamine results in decreased expression of TRIM67 mRNA CTD PMID:26307267 NCBI chr19:52,763,991...52,805,906
Ensembl chr19:52,764,387...52,800,422
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 increases expression ISO Methamphetamine results in increased expression of TRIP10 mRNA CTD PMID:26307267 NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799
JBrowse link
G Trmt1 tRNA methyltransferase 1 increases expression ISO Methamphetamine results in increased expression of TRMT1 mRNA CTD PMID:26307267 NCBI chr19:23,456,756...23,471,581
Ensembl chr19:23,456,756...23,466,956
JBrowse link
G Trnp1 TMF1-regulated nuclear protein 1 increases expression EXP Methamphetamine results in increased expression of TRNP1 mRNA CTD PMID:28341135 NCBI chr 5:145,706,427...145,713,279
Ensembl chr 5:145,706,094...145,713,272
JBrowse link
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 affects response to substance ISO TRPM3 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases expression ISO Methamphetamine results in increased expression of TRPV1 mRNA CTD PMID:20122992 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Tsc2 TSC complex subunit 2 multiple interactions
increases phosphorylation
ISO
EXP
DDIT4 protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein]
CEBPB protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein]
CTD PMID:31059759 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression
decreases expression
multiple interactions
EXP
ISO
Methamphetamine results in increased expression of TSC22D3 mRNA
Methamphetamine results in decreased expression of TSC22D3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of TSC22D3 mRNA
CTD PMID:19564919 PMID:36914120 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tspan4 tetraspanin 4 decreases expression ISO Methamphetamine results in decreased expression of TSPAN4 mRNA CTD PMID:36914120 NCBI chr 1:196,571,307...196,593,842
Ensembl chr 1:196,572,228...196,617,448
JBrowse link
G Ttc39a tetratricopeptide repeat domain 39A increases expression ISO Methamphetamine results in increased expression of TTC39A mRNA CTD PMID:26307267 NCBI chr 5:124,165,102...124,204,740
Ensembl chr 5:124,151,760...124,204,973
JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B increases expression EXP Methamphetamine results in increased expression of TTC39B mRNA CTD PMID:19564919 NCBI chr 5:97,603,329...97,708,103
Ensembl chr 5:97,609,392...97,736,270
JBrowse link
G Ttk Ttk protein kinase multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TTK mRNA
Methamphetamine results in decreased expression of TTK mRNA
CTD PMID:19564919 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Ttll12 tubulin tyrosine ligase like 12 increases expression EXP Methamphetamine results in increased expression of TTLL12 mRNA CTD PMID:19564919 NCBI chr 7:114,731,890...114,751,237
Ensembl chr 7:114,731,892...114,751,356
JBrowse link
G Ttll4 tubulin tyrosine ligase like 4 increases expression ISO Methamphetamine results in increased expression of TTLL4 mRNA CTD PMID:26307267 NCBI chr 9:76,221,659...76,258,219
Ensembl chr 9:76,221,796...76,251,301
JBrowse link
G Ttll9 tubulin tyrosine ligase like 9 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of TTLL9 mRNA
Methamphetamine results in decreased expression of TTLL9 mRNA
CTD PMID:19564919 NCBI chr 3:141,429,351...141,475,965
Ensembl chr 3:141,429,444...141,475,865
JBrowse link
G Ttn titin increases expression ISO Methamphetamine results in increased expression of TTN mRNA CTD PMID:26307267 NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Ttpal alpha tocopherol transfer protein like decreases methylation ISO Methamphetamine results in decreased methylation of TTPAL promoter CTD PMID:26307267 NCBI chr 3:152,278,246...152,296,550
Ensembl chr 3:152,278,303...152,296,513
JBrowse link
G Tuba1b tubulin, alpha 1B decreases expression EXP Methamphetamine results in decreased expression of TUBA1B protein CTD PMID:19826936 NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Tuba1c tubulin, alpha 1C increases expression ISO Methamphetamine results in increased expression of TUBA1C mRNA CTD PMID:36914120 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP Methamphetamine results in decreased expression of TUBB2A protein CTD PMID:19826936 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Methamphetamine results in decreased expression of TUBB4B protein CTD PMID:19826936 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression EXP Methamphetamine results in increased expression of TUBB5 protein CTD PMID:19826936 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial decreases expression EXP Methamphetamine results in decreased expression of TUFM protein CTD PMID:19826936 NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
JBrowse link
G Tut1 terminal uridylyl transferase 1, U6 snRNA-specific increases expression ISO Methamphetamine results in increased expression of TUT1 mRNA CTD PMID:26307267 NCBI chr 1:205,848,691...205,859,767
Ensembl chr 1:205,848,772...205,859,764
JBrowse link
G Txn1 thioredoxin 1 decreases expression
decreases response to substance
multiple interactions
ISO Methamphetamine results in decreased expression of TXN1 protein
TXN protein results in decreased susceptibility to Methamphetamine
TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP12 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP3 protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of HSPA5 protein]
CTD PMID:32203791 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions
decreases expression
affects localization
EXP 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the localization of UBA1 mRNA]
Methamphetamine results in decreased expression of UBA1 mRNA
CTD PMID:18299792 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636
JBrowse link
G Uba1y ubiquitin-activating enzyme, Chr Y decreases expression ISO Methamphetamine results in decreased expression of UBA1Y mRNA CTD PMID:26307267 NCBI chr  Y:457,617...480,306
Ensembl chr  Y:459,843...480,216
JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of UBA2 mRNA
Methamphetamine results in increased expression of UBA2 mRNA
CTD PMID:19564919 NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682
JBrowse link
G Ubc ubiquitin C increases expression EXP Methamphetamine results in increased expression of UBC mRNA CTD PMID:24042092 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression EXP Methamphetamine results in decreased expression of UBE2C mRNA CTD PMID:28341135 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression EXP Methamphetamine affects the expression of UBE2N protein CTD PMID:17904249 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T decreases expression EXP Methamphetamine results in decreased expression of UBE2T mRNA CTD PMID:28341135 NCBI chr13:46,403,352...46,413,854
Ensembl chr13:46,403,375...46,414,835
JBrowse link
G Ubl4b ubiquitin-like 4B decreases expression ISO Methamphetamine results in decreased expression of UBL4B mRNA CTD PMID:26307267 NCBI chr 2:195,192,490...195,193,820
Ensembl chr 2:195,191,720...195,193,875
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 increases expression ISO Methamphetamine results in increased expression of UBR2 mRNA CTD PMID:36914120 NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139
JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 increases expression ISO Methamphetamine results in increased expression of UBR4 mRNA CTD PMID:26307267 NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 decreases expression
increases expression
ISO
EXP
Methamphetamine results in decreased expression of UCHL1 protein
Methamphetamine results in increased expression of UCHL1 protein
CTD PMID:16181420 PMID:19826936 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Uck2 uridine-cytidine kinase 2 increases expression ISO Methamphetamine results in increased expression of UCK2 mRNA CTD PMID:36914120 NCBI chr13:79,380,807...79,438,121
Ensembl chr13:79,383,846...79,438,352
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 increases expression EXP Methamphetamine results in increased expression of ULK1 CTD PMID:32676729 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
G Unk unk zinc finger increases expression ISO Methamphetamine results in increased expression of UNK mRNA CTD PMID:26307267 NCBI chr10:101,265,732...101,295,950
Ensembl chr10:101,265,703...101,295,967
JBrowse link
G Upp1 uridine phosphorylase 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of UPP1 mRNA
Methamphetamine results in increased expression of UPP1 mRNA
CTD PMID:19564919 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
JBrowse link
G Urgcp upregulator of cell proliferation increases expression ISO Methamphetamine results in increased expression of URGCP mRNA CTD PMID:36914120 NCBI chr14:80,594,637...80,638,972
Ensembl chr14:80,594,633...80,619,888
JBrowse link
G Ush1c USH1 protein network component harmonin increases expression ISO Methamphetamine results in increased expression of USH1C mRNA CTD PMID:26307267 NCBI chr 1:96,695,303...96,743,671
Ensembl chr 1:96,695,307...96,743,671
JBrowse link
G Ush2a usherin decreases methylation ISO Methamphetamine results in decreased methylation of USH2A promoter CTD PMID:26307267 NCBI chr13:99,837,445...100,503,935
Ensembl chr13:99,837,445...100,503,922
JBrowse link
G Usp20 ubiquitin specific peptidase 20 increases expression ISO Methamphetamine results in increased expression of USP20 mRNA CTD PMID:26307267 NCBI chr 3:14,272,737...14,306,409
Ensembl chr 3:14,272,908...14,306,409
JBrowse link
G Usp48 ubiquitin specific peptidase 48 affects response to substance ISO USP48 gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr 5:149,800,189...149,867,838
Ensembl chr 5:149,800,179...149,867,719
JBrowse link
G Uspl1 ubiquitin specific peptidase like 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of USPL1 mRNA
Methamphetamine results in increased expression of USPL1 mRNA
CTD PMID:19564919 NCBI chr12:5,823,460...5,850,470
Ensembl chr12:5,823,359...5,850,366
JBrowse link
G Utp18 UTP18 small subunit processome component decreases expression EXP Methamphetamine results in decreased expression of UTP18 mRNA CTD PMID:19564919 NCBI chr10:78,811,879...78,839,338
Ensembl chr10:78,811,880...78,839,627
JBrowse link
G Utrn utrophin increases expression ISO Methamphetamine results in increased expression of UTRN mRNA CTD PMID:26307267 NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 increases expression EXP Methamphetamine results in increased expression of VAMP8 mRNA CTD PMID:34374793 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897
JBrowse link
G Vcsa2 variable coding sequence A2 decreases expression EXP Methamphetamine results in decreased expression of VCSA2 mRNA CTD PMID:15644446 NCBI chr14:19,851,232...19,857,697
Ensembl chr14:19,851,232...19,857,697
JBrowse link
G Vdac1 voltage-dependent anion channel 1 decreases expression EXP Methamphetamine results in decreased expression of VDAC1 protein CTD PMID:19826936 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vdac2 voltage-dependent anion channel 2 decreases expression EXP Methamphetamine results in decreased expression of VDAC2 protein CTD PMID:19826936 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions
EXP Methamphetamine results in increased expression of VEGFA mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of VEGFA mRNA]
CTD PMID:15644446 PMID:19564919 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vgf VGF nerve growth factor inducible increases expression EXP Methamphetamine results in increased expression of VGF mRNA CTD PMID:19564919 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO Methamphetamine results in increased expression of VLDLR mRNA CTD PMID:26307267 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Vom2r31 vomeronasal 2 receptor, 31 decreases expression EXP Methamphetamine results in decreased expression of VOM2R31 mRNA CTD PMID:19564919 NCBI chr 1:71,183,055...71,211,273
Ensembl chr 1:71,185,371...71,211,267
Ensembl chr 1:71,185,371...71,211,267
JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes increases expression ISO Methamphetamine results in increased expression of VPS11 mRNA CTD PMID:26307267 NCBI chr 8:44,684,129...44,698,568
Ensembl chr 8:44,684,127...44,698,568
JBrowse link
G Vps29 VPS29 retromer complex component decreases expression ISO Methamphetamine results in decreased expression of VPS29 mRNA CTD PMID:26307267 NCBI chr12:34,208,911...34,217,977
Ensembl chr12:34,207,263...34,217,964
JBrowse link
G Vps35 VPS35 retromer complex component increases expression ISO Methamphetamine results in increased expression of VPS35 mRNA; Methamphetamine results in increased expression of VPS35 protein CTD PMID:35643125 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618
JBrowse link
G Vps37b VPS37B subunit of ESCRT-I increases expression EXP Methamphetamine results in increased expression of VPS37B mRNA CTD PMID:19564919 NCBI chr12:32,560,047...32,589,015
Ensembl chr12:32,560,047...32,589,014
JBrowse link
G Vwf von Willebrand factor multiple interactions
increases expression
EXP Luteolin inhibits the reaction [Methamphetamine results in increased expression of VWF mRNA] CTD PMID:32035215 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Vxn vexin increases expression EXP Methamphetamine results in increased expression of VXN mRNA CTD PMID:32035215 NCBI chr 5:9,659,213...9,684,684
Ensembl chr 5:9,659,213...9,684,684
JBrowse link
G Wasf2 WASP family member 2 increases expression ISO Methamphetamine results in increased expression of WASF2 mRNA CTD PMID:26307267 NCBI chr 5:145,336,817...145,402,041
Ensembl chr 5:145,336,842...145,399,242
JBrowse link
G Washc2c WASH complex subunit 2C decreases methylation
increases expression
ISO Methamphetamine results in decreased methylation of WASHC2 promoter
Methamphetamine results in increased expression of WASHC2 mRNA
CTD PMID:26307267 NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:149,267,924...149,325,851
JBrowse link
G Wwc2 WW and C2 domain containing 2 increases expression ISO Methamphetamine results in increased expression of WWC2 mRNA CTD PMID:26307267 NCBI chr16:44,258,372...44,421,815
Ensembl chr16:44,258,372...44,421,812
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions
increases expression
EXP
ISO
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of XBP1 protein alternative form]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of XBP1 mRNA alternative form]; Methamphetamine results in increased expression of and results in increased splicing of XBP1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased splicing of XBP1 mRNA]
Methamphetamine results in increased expression of XBP1 mRNA; Methamphetamine results in increased expression of XBP1 protein
ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 protein]
Methamphetamine results in increased expression of XBP1 mRNA; Methamphetamine results in increased expression of XBP1 mRNA alternative form; Methamphetamine results in increased expression of XBP1 protein alternative form
CTD PMID:19564919 PMID:27323860 PMID:28070110 PMID:34214594 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xdh xanthine dehydrogenase increases expression ISO Methamphetamine results in increased expression of XDH mRNA CTD PMID:26307267 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Xirp1 xin actin-binding repeat containing 1 increases expression ISO Methamphetamine results in increased expression of XIRP1 mRNA CTD PMID:36914120 NCBI chr 8:119,744,778...119,757,547
Ensembl chr 8:119,747,419...119,757,349
JBrowse link
G Xpo6 exportin 6 increases expression ISO Methamphetamine results in increased expression of XPO6 mRNA CTD PMID:26307267 NCBI chr 1:180,672,114...180,761,543
Ensembl chr 1:180,672,119...180,761,543
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 increases expression ISO Methamphetamine results in increased expression of XRCC1 mRNA CTD PMID:26307267 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
G Xrn1 5'-3' exoribonuclease 1 increases expression EXP Methamphetamine results in increased expression of XRN1 mRNA CTD PMID:19564919 NCBI chr 8:96,527,871...96,637,385
Ensembl chr 8:96,528,195...96,632,739
JBrowse link
G Ybx1 Y box binding protein 1 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of YBX1 mRNA
Methamphetamine results in increased expression of YBX1 mRNA
CTD PMID:19564919 NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta decreases expression ISO Methamphetamine results in decreased expression of YWHAB mRNA CTD PMID:26307267 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
JBrowse link
G Zbtb40 zinc finger and BTB domain containing 40 decreases expression EXP Methamphetamine results in decreased expression of ZBTB40 mRNA CTD PMID:19564919 NCBI chr 5:149,216,496...149,283,746
Ensembl chr 5:149,219,677...149,254,415
JBrowse link
G Zc3h11a zinc finger CCCH-type containing 11A increases expression ISO Methamphetamine results in increased expression of ZC3H11A mRNA CTD PMID:26307267 NCBI chr13:45,073,422...45,113,901
Ensembl chr13:45,071,718...45,114,009
JBrowse link
G Zc3h6 zinc finger CCCH type containing 6 decreases expression EXP Methamphetamine results in decreased expression of ZC3H6 mRNA CTD PMID:19564919 NCBI chr 3:116,203,466...116,254,186
Ensembl chr 3:116,204,197...116,253,282
JBrowse link
G Zcchc12 zinc finger CCHC-type containing 12 decreases expression EXP Methamphetamine results in decreased expression of ZCCHC12 mRNA CTD PMID:32035215 NCBI chr  X:115,433,444...115,436,691
Ensembl chr  X:115,433,259...115,436,692
JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 decreases methylation ISO Methamphetamine results in decreased methylation of ZDHHC3 promoter CTD PMID:26307267 NCBI chr 8:122,725,206...122,773,542
Ensembl chr 8:122,715,111...122,773,529
JBrowse link
G Zfand2a zinc finger AN1-type containing 2A increases expression EXP Methamphetamine results in increased expression of ZFAND2A mRNA CTD PMID:19564919 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
JBrowse link
G Zfp1 zinc finger protein 1 increases expression ISO Methamphetamine results in increased expression of ZFP1 mRNA CTD PMID:26307267 NCBI chr19:39,599,497...39,633,490
Ensembl chr19:39,599,954...39,632,995
JBrowse link
G Zfp142 zinc finger protein 142 increases expression ISO Methamphetamine results in increased expression of ZFP142 mRNA CTD PMID:26307267 NCBI chr 9:76,141,053...76,164,784
Ensembl chr 9:76,142,227...76,164,856
JBrowse link
G Zfp189 zinc finger protein 189 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in increased expression of ZFP189 mRNA
Methamphetamine results in increased expression of ZFP189 mRNA
CTD PMID:19564919 NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121
JBrowse link
G Zfp287 zinc finger protein 287 multiple interactions
increases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZFP287 mRNA
Methamphetamine results in increased expression of ZFP287 mRNA
CTD PMID:19564919 NCBI chr10:47,395,650...47,415,610
Ensembl chr10:47,397,285...47,439,755
JBrowse link
G Zfp354a zinc finger protein 354A increases expression EXP Methamphetamine results in increased expression of ZFP354A mRNA CTD PMID:19564919 NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068
JBrowse link
G Zfp36 zinc finger protein 36 increases expression
decreases expression
multiple interactions
ISO
EXP
Methamphetamine results in increased expression of ZFP36 mRNA
Methamphetamine results in decreased expression of ZFP36 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of ZFP36 mRNA
CTD PMID:19564919 PMID:26307267 PMID:36914120 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp366 zinc finger protein 366 decreases expression ISO Methamphetamine results in decreased expression of ZFP366 mRNA CTD PMID:36914120 NCBI chr 2:30,578,552...30,640,546
Ensembl chr 2:30,578,715...30,642,182
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 increases expression EXP Methamphetamine results in increased expression of ZFP36L1 mRNA CTD PMID:19564919 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
G Zfp385d zinc finger protein 385D affects response to substance ISO ZNF385D gene SNP affects the susceptibility to Methamphetamine CTD PMID:18316681 NCBI chr15:5,040,182...5,849,975
Ensembl chr15:5,042,572...5,423,367
JBrowse link
G Zfp414 zinc finger protein 414 decreases expression EXP Methamphetamine results in decreased expression of ZFP414 mRNA CTD PMID:19564919 NCBI chr 7:14,420,232...14,422,939
Ensembl chr 7:14,420,165...14,438,166
JBrowse link
G Zfp532 zinc finger protein 532 increases expression ISO Methamphetamine results in increased expression of ZFP532 mRNA CTD PMID:26307267 NCBI chr18:59,080,082...59,203,672
Ensembl chr18:59,092,789...59,203,666
JBrowse link
G Zfp541 zinc finger protein 541 decreases expression ISO Methamphetamine results in decreased expression of ZFP541 mRNA CTD PMID:26307267 NCBI chr 1:76,750,236...76,786,567
Ensembl chr 1:76,750,236...76,786,567
JBrowse link
G Zfp609 zinc finger protein 609 increases expression ISO Methamphetamine results in increased expression of ZFP609 mRNA CTD PMID:26307267 NCBI chr 8:66,214,553...66,349,319
Ensembl chr 8:66,214,555...66,317,977
JBrowse link
G Zfp638 zinc finger protein 638 increases expression ISO Methamphetamine results in increased expression of ZFP638 mRNA CTD PMID:26307267 NCBI chr 4:116,355,934...116,475,051
Ensembl chr 4:116,402,428...116,479,845
JBrowse link
G Zfp688 zinc finger protein 688 multiple interactions
decreases expression
EXP [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZFP688 mRNA
Methamphetamine results in decreased expression of ZFP688 mRNA
CTD PMID:19564919 NCBI chr 1:182,039,366...182,043,035
Ensembl chr 1:182,039,931...182,043,103
JBrowse link
G Zfp775 zinc finger protein 775 increases expression ISO Methamphetamine results in increased expression of ZFP775 mRNA CTD PMID:26307267 NCBI chr 4:77,557,037...77,575,296
Ensembl chr 4:77,548,847...77,575,296
JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 decreases expression EXP Methamphetamine results in decreased expression of ZFYVE16 mRNA CTD PMID:19564919 NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990
JBrowse link
G Zic2 Zic family member 2 decreases expression
multiple interactions
EXP Methamphetamine results in decreased expression of ZIC2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ZIC2 mRNA
CTD PMID:19564919 NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression
affects response to substance
ISO
EXP
Methamphetamine results in increased expression of ZMAT3 protein
ZMAT3 protein affects the susceptibility to Methamphetamine
CTD PMID:17234339 NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 increases expression ISO Methamphetamine results in increased expression of ZMIZ2 mRNA CTD PMID:26307267 NCBI chr14:81,251,391...81,267,936
Ensembl chr14:81,251,417...81,267,936
JBrowse link
G Zmynd12 zinc finger, MYND-type containing 12 decreases expression EXP Methamphetamine results in decreased expression of ZMYND12 mRNA CTD PMID:19564919 NCBI chr 5:133,026,917...133,059,985
Ensembl chr 5:133,027,009...133,059,995
JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 increases expression ISO Methamphetamine results in increased expression of ZMYND8 mRNA CTD PMID:26307267 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463
JBrowse link
G Znfx1 zinc finger, NFX1-type containing 1 increases expression ISO Methamphetamine results in increased expression of ZNFX1 mRNA CTD PMID:26307267 NCBI chr 3:155,764,073...155,791,777
Ensembl chr 3:155,764,980...155,821,242
JBrowse link
G Znrf1 zinc and ring finger 1 increases expression ISO Methamphetamine results in increased expression of ZNRF1 mRNA CTD PMID:26307267 NCBI chr19:39,496,414...39,581,600
Ensembl chr19:39,496,527...39,580,969
JBrowse link
G Zzef1 zinc finger ZZ-type and EF-hand domain containing 1 increases expression ISO Methamphetamine results in increased expression of ZZEF1 mRNA CTD PMID:26307267 NCBI chr10:57,413,265...57,550,888
Ensembl chr10:57,411,149...57,549,568
JBrowse link
N-ethylmaleimide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO Ethylmaleimide results in decreased activity of ABCB1 protein CTD PMID:2900677 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects activity
multiple interactions
ISO Ethylmaleimide affects the activity of ABCC1 protein
Ethylmaleimide inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]
CTD PMID:9096673 PMID:9334814 PMID:16101123 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Alb albumin decreases transport EXP Ethylmaleimide results in decreased transport of ALB protein CTD PMID:15897811 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions ISO Ethylmaleimide inhibits the reaction [APEX1 protein inhibits the reaction [Hydrogen Peroxide results in decreased activity of MAPK1 protein]] CTD PMID:23370007 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions
increases glutathionylation
ISO Dithiothreitol inhibits the reaction [Ethylmaleimide results in increased glutathionylation of ATP7A protein] CTD PMID:20566629 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions EXP Ethylmaleimide inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] CTD PMID:11584374 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Cbr2 carbonyl reductase 2 increases acylation ISO Ethylmaleimide results in increased acylation of CBR2 protein CTD PMID:18597497 NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Ethylmaleimide inhibits the reaction [Glutathione results in decreased activity of CFTR protein] CTD PMID:15657297 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chat choline O-acetyltransferase decreases activity ISO Ethylmaleimide results in decreased activity of CHAT protein CTD PMID:3437937 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Ethylmaleimide inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Dusp23 dual specificity phosphatase 23 multiple interactions ISO Ethylmaleimide inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate] CTD PMID:15147733 NCBI chr13:85,097,899...85,100,054
Ensembl chr13:85,097,899...85,100,093
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO Ethylmaleimide results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases activity ISO Ethylmaleimide results in decreased activity of GAD1 protein CTD PMID:15836621 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gad2 glutamate decarboxylase 2 decreases activity ISO Ethylmaleimide results in decreased activity of GAD2 protein CTD PMID:15836621 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
G Hoxb13 homeo box B13 increases response to substance ISO HOXB13 protein results in increased susceptibility to Ethylmaleimide CTD PMID:24213000 NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions ISO Ethylmaleimide promotes the reaction [Thiram results in decreased activity of HSD11B2 protein] CTD PMID:22796344 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Ltbr lymphotoxin beta receptor multiple interactions ISO Ethylmaleimide promotes the reaction [OSM protein binds to LTBR protein] CTD PMID:37193757 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Ethylmaleimide inhibits the reaction [APEX1 protein inhibits the reaction [Hydrogen Peroxide results in decreased activity of MAPK1 protein]] CTD PMID:23370007 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mt3 metallothionein 3 increases alkylation ISO Ethylmaleimide results in increased alkylation of MT3 protein CTD PMID:12383939 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Osm oncostatin M multiple interactions ISO Ethylmaleimide promotes the reaction [OSM protein binds to LTBR protein] CTD PMID:37193757 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Pah phenylalanine hydroxylase multiple interactions ISO Ethylmaleimide results in increased activity of [PAH protein binds to PAH protein binds to PAH protein binds to PAH protein] CTD PMID:19367645 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
G Senp1 SUMO specific peptidase 1 multiple interactions ISO Ethylmaleimide inhibits the reaction [SUMO2 protein binds to SENP1 protein] CTD PMID:26060329 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598
JBrowse link
G Senp6 SUMO specific peptidase 6 multiple interactions ISO Ethylmaleimide inhibits the reaction [SUMO2 protein binds to SENP6 protein] CTD PMID:26060329 NCBI chr 8:80,988,675...81,071,606
Ensembl chr 8:80,989,052...81,067,170
JBrowse link
G Slc12a5 solute carrier family 12 member 5 increases activity
multiple interactions
ISO Ethylmaleimide results in increased activity of SLC12A5 protein
Ethylmaleimide inhibits the reaction [SLC12A5 protein results in increased import of Thallium]
CTD PMID:20086212 NCBI chr 3:153,696,517...153,735,801
Ensembl chr 3:153,696,517...153,735,765
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO Ethylmaleimide inhibits the reaction [SLC16A1 protein results in increased uptake of Lactic Acid] CTD PMID:15804185 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; Ethylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Ethylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO Ethylmaleimide inhibits the reaction [CD 437 results in increased cleavage of SP1 protein] CTD PMID:9343396 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Sumo2 small ubiquitin-like modifier 2 multiple interactions ISO Ethylmaleimide inhibits the reaction [SUMO2 protein binds to SENP1 protein]; Ethylmaleimide inhibits the reaction [SUMO2 protein binds to SENP6 protein] CTD PMID:26060329 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513
JBrowse link
G Tf transferrin decreases uptake ISO Ethylmaleimide results in decreased uptake of TF protein CTD PMID:10865941 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP Ethylmaleimide inhibits the reaction [Clozapine results in decreased expression of TH protein] CTD PMID:15983997 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Ethylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Ethylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vdac1 voltage-dependent anion channel 1 affects binding EXP Ethylmaleimide binds to VDAC1 protein CTD PMID:20192921 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
N-nitrosopiperidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO CYP2E1 protein affects the metabolism of and results in increased activity of N-nitrosopiperidine CTD PMID:11774366 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO N-nitrosopiperidine results in increased cleavage of PARP1 protein CTD PMID:17929238 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
nortriptyline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
affects response to substance
ISO ABCB1A protein results in increased transport of Nortriptyline; ABCB1A protein results in increased transport of Nortriptyline metabolite
ABCB1 exon SNP affects the susceptibility to Nortriptyline
CTD PMID:10700657 PMID:12082591 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Nortriptyline results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Casp3 caspase 3 decreases activity
increases activity
multiple interactions
ISO Nortriptyline results in decreased activity of CASP3 protein
Nortriptyline results in increased activity of CASP3 protein
Palmitic Acid promotes the reaction [Nortriptyline results in increased activity of CASP3 protein]
CTD PMID:17686041 PMID:18174477 PMID:22700542 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO Palmitic Acid promotes the reaction [Nortriptyline results in increased activity of CASP7 protein] CTD PMID:22700542 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Cycs cytochrome c, somatic decreases secretion ISO Nortriptyline results in decreased secretion of CYCS protein CTD PMID:17686041 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing ISO Nortriptyline results in increased metabolism of CYP1A2 protein CTD PMID:18359012 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
multiple interactions
ISO Nortriptyline results in decreased activity of CYP2C8 protein
torsemide inhibits the reaction [Nortriptyline results in decreased activity of CYP2C8 protein]
CTD PMID:15304522
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases response to substance
multiple interactions
increases metabolic processing
increases hydroxylation
ISO CYP2D6 gene mutant form results in decreased susceptibility to Nortriptyline
Paroxetine inhibits the reaction [CYP2D6 gene mutant form results in decreased susceptibility to Nortriptyline]
Nortriptyline results in increased metabolism of CYP2D6 protein
CYP2D6 protein results in increased hydroxylation of Nortriptyline
CTD PMID:11673748 PMID:17470523 PMID:18359012 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO Nortriptyline results in increased metabolism of CYP3A4 protein CTD PMID:18359012 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases metabolic processing ISO Nortriptyline results in increased metabolism of CYP3A5 protein CTD PMID:18359012 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Gnb3 G protein subunit beta 3 decreases response to substance
increases response to substance
ISO GNB3 gene polymorphism results in decreased susceptibility to Nortriptyline
GNB3 protein results in increased susceptibility to Nortriptyline
CTD PMID:14604448 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C decreases expression ISO Nortriptyline results in decreased expression of HTR2C protein CTD PMID:8131152 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Nortriptyline CTD PMID:19362101 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Nortriptyline CTD PMID:19362101 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO Nortriptyline inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:21158687 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Pf4 platelet factor 4 affects expression ISO Nortriptyline affects the expression of PF4 protein CTD PMID:10770450 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Ppbp pro-platelet basic protein affects expression ISO Nortriptyline affects the expression of PPBP protein CTD PMID:10770450 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Nortriptyline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc6a2 solute carrier family 6 member 2 affects response to substance ISO SLC6A2 gene polymorphism affects the susceptibility to Nortriptyline CTD PMID:17018806 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
JBrowse link
G Slc6a4 solute carrier family 6 member 4 affects response to substance
increases response to substance
decreases response to substance
ISO SLC6A4 polymorphism affects the susceptibility to Nortriptyline; SLC6A4 promoter polymorphism affects the susceptibility to Nortriptyline
SLC6A4 protein results in increased susceptibility to Nortriptyline
SLC6A4 gene polymorphism results in decreased susceptibility to Nortriptyline
CTD PMID:14604448 PMID:17018806 PMID:21658141 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Nortriptyline CTD PMID:19362101 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
phencyclidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor decreases expression ISO Phencyclidine results in decreased expression of ADORA2A mRNA CTD PMID:17266109 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Ajuba ajuba LIM protein increases expression ISO Phencyclidine results in increased expression of AJUBA mRNA CTD PMID:12105081 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO Phencyclidine results in increased expression of ALDH1A1 mRNA CTD PMID:17266109 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Apod apolipoprotein D increases expression ISO Phencyclidine results in increased expression of APOD mRNA CTD PMID:17266109 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G Apol2 apolipoprotein L, 2 increases expression ISO Phencyclidine results in increased expression of APOL2 mRNA CTD PMID:17205118 NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558
JBrowse link
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 decreases expression ISO Phencyclidine results in decreased expression of ARHGEF9 mRNA CTD PMID:17266109 NCBI chr  X:59,919,560...60,077,538
Ensembl chr  X:59,920,870...60,077,513
JBrowse link
G Calm1 calmodulin 1 decreases expression ISO Phencyclidine results in decreased expression of CALM1 mRNA CTD PMID:17205118 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Phencyclidine results in decreased expression of CALM2 mRNA CTD PMID:17205118 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression
decreases expression
ISO Phencyclidine results in increased expression of CAMK2A mRNA
Phencyclidine results in decreased expression of CAMK2A mRNA
CTD PMID:17266109 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression ISO Phencyclidine results in decreased expression of CAMK2B mRNA CTD PMID:17205118 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Casp1 caspase 1 increases expression ISO Phencyclidine results in increased expression of CASP1 mRNA CTD PMID:12105081 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Phencyclidine results in increased activity of CASP3 protein]]; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Phencyclidine results in increased activity of CASP3 protein]; Cadmium Chloride inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Phencyclidine results in increased activity of CASP3 protein]]; Nifedipine inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Phencyclidine results in increased activity of CASP3 protein]]; omega-agatoxin-Aa4b inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Phencyclidine results in increased activity of CASP3 protein]]; staurosporine aglycone inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Phencyclidine results in increased activity of CASP3 protein]] CTD PMID:24995437 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cckbr cholecystokinin B receptor increases expression ISO Phencyclidine results in increased expression of CCKBR mRNA CTD PMID:17266109 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases expression ISO Phencyclidine results in increased expression of CDK5R1 mRNA CTD PMID:17266109 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression
increases expression
ISO Phencyclidine results in decreased expression of CNP mRNA
Phencyclidine results in increased expression of CNP mRNA
CTD PMID:17266109 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO [Phencyclidine co-treated with Dronabinol] results in decreased expression of CNR1 protein CTD PMID:28648819 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cplx2 complexin 2 decreases expression ISO Phencyclidine results in decreased expression of CPLX2 mRNA CTD PMID:17266109 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
increases activity
ISO acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; ginsenoside Re inhibits the reaction [Phencyclidine results in increased activity of CYBA protein]; GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein] CTD PMID:29037473 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity
affects metabolic processing
affects oxidation
ISO Phencyclidine analog results in decreased activity of CYP2B6 protein; Phencyclidine results in decreased activity of CYP2B6 protein
CYP2B6 protein affects the metabolism of Phencyclidine analog
CYP2B6 protein affects the oxidation of Phencyclidine
CTD PMID:16782764 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 affects metabolic processing ISO CYP2C9 protein affects the metabolism of Phencyclidine CTD PMID:16782764 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 affects oxidation
decreases activity
ISO CYP2C19 protein affects the oxidation of Phencyclidine
Phencyclidine results in decreased activity of CYP2C19 protein
CTD PMID:16782764 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 affects metabolic processing ISO CYP2C8 protein affects the metabolism of Phencyclidine CTD PMID:16782764
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects metabolic processing ISO CYP2D6 protein affects the metabolism of Phencyclidine CTD PMID:16782764 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing ISO CYP3A4 protein affects the metabolism of Phencyclidine CTD PMID:16782764 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing ISO CYP3A5 protein affects the metabolism of Phencyclidine CTD PMID:16782764 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Ddo D-aspartate oxidase multiple interactions
affects response to substance
ISO [DDO protein affects the susceptibility to Phencyclidine] which affects the expression of DLG4 mRNA; [DDO protein affects the susceptibility to Phencyclidine] which affects the expression of HOMER1 mRNA; DDO protein affects the reaction [Phencyclidine results in decreased expression of HOMER1 mRNA]; DDO protein affects the reaction [Phencyclidine results in increased expression of DLG4 mRNA] CTD PMID:25979765 NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
increases expression
ISO [DDO protein affects the susceptibility to Phencyclidine] which affects the expression of DLG4 mRNA; DDO protein affects the reaction [Phencyclidine results in increased expression of DLG4 mRNA] CTD PMID:25979765 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 decreases expression ISO Phencyclidine results in decreased expression of DNAJC1 mRNA CTD PMID:12105081 NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988
JBrowse link
G Drd1 dopamine receptor D1 decreases expression
multiple interactions
ISO Phencyclidine results in decreased expression of DRD1 mRNA; Phencyclidine results in decreased expression of DRD1 protein
NTSR1 gene affects the reaction [Phencyclidine results in decreased expression of DRD1 protein]
CTD PMID:17266109 PMID:20659557 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 decreases expression
affects binding
ISO
EXP
Phencyclidine results in decreased expression of DRD2 mRNA; Phencyclidine results in decreased expression of DRD2 protein
Phencyclidine binds to Drd2 protein
CTD
RGD
PMID:17266109 PMID:20659557 PMID:15852061 RGD:1581406 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Egf epidermal growth factor increases expression ISO Phencyclidine results in increased expression of EGF mRNA CTD PMID:12105081 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Phencyclidine results in increased expression of FDFT1 mRNA CTD PMID:17205118 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP [Dextroamphetamine co-treated with Phencyclidine] promotes the reaction [FOS protein binds to FOS promoter]; [Dextroamphetamine co-treated with Phencyclidine] promotes the reaction [SRF protein binds to FOS promoter]; [Dextroamphetamine co-treated with Phencyclidine] results in increased expression of FOS protein; [Phencyclidine co-treated with Dextroamphetamine] results in increased expression of FOS protein; Phencyclidine promotes the reaction [FOS protein binds to FOS promoter]; Phencyclidine promotes the reaction [SRF protein binds to FOS promoter]
Phencyclidine results in increased expression of FOS protein
CTD PMID:12510024 PMID:16678866 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP [Phencyclidine co-treated with Dextroamphetamine] results in increased expression of FOSB protein
Phencyclidine results in increased expression of FOSB protein
CTD PMID:16678866 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Foxp2 forkhead box P2 increases expression ISO Phencyclidine results in increased expression of FOXP2 mRNA CTD PMID:17266109 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 decreases expression ISO Phencyclidine results in decreased expression of GABBR1 mRNA CTD PMID:17266109 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 increases expression ISO Phencyclidine results in increased expression of GABRA1 mRNA CTD PMID:17266109 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gad2 glutamate decarboxylase 2 increases expression ISO Phencyclidine results in increased expression of GAD2 mRNA CTD PMID:17266109 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
G Gap43 growth associated protein 43 increases expression EXP Phencyclidine results in increased expression of GAP43 mRNA CTD PMID:11377751 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 increases expression ISO Phencyclidine results in increased expression of GCC1 mRNA CTD PMID:17205118 NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663
JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO Phencyclidine results in increased expression of GFAP mRNA CTD PMID:17266109 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gnas GNAS complex locus increases expression ISO Phencyclidine results in increased expression of GNAS mRNA CTD PMID:12105081 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]; GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]; GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]; GPX1 protein affects the reaction [Phencyclidine results in increased activity of CYBA protein]; GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein] CTD PMID:29037473 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 increases expression ISO Phencyclidine results in increased expression of GRIA4 mRNA CTD PMID:17266109 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
multiple interactions
ISO Phencyclidine results in decreased expression of GRIN1 mRNA; Phencyclidine results in decreased expression of GRIN1 protein
[Phencyclidine co-treated with Dronabinol] results in decreased expression of GRIN1 protein
CTD PMID:17266109 PMID:28648819 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression ISO Phencyclidine results in decreased expression of GRIN2A mRNA; Phencyclidine results in decreased expression of GRIN2A protein CTD PMID:20659557 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP Phencyclidine results in increased expression of HMOX1 mRNA; Phencyclidine results in increased expression of HMOX1 protein
1,3-dimethylthiourea inhibits the reaction [Phencyclidine results in increased expression of HMOX1 protein]
CTD PMID:9875361 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions
decreases expression
ISO [DDO protein affects the susceptibility to Phencyclidine] which affects the expression of HOMER1 mRNA; DDO protein affects the reaction [Phencyclidine results in decreased expression of HOMER1 mRNA] CTD PMID:25979765 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO Phencyclidine results in decreased expression of HOXB9 mRNA CTD PMID:12105081 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
decreases activity
EXP [Phencyclidine co-treated with Haloperidol] affects the activity of HTR2A protein; Clozapine promotes the reaction [Phencyclidine results in decreased activity of HTR2A protein] CTD PMID:15380371 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Phencyclidine co-treated with Dextroamphetamine] results in increased expression of JUND protein CTD PMID:16678866 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 decreases expression ISO Phencyclidine results in decreased expression of KCNH1 mRNA CTD PMID:12105081 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 increases expression ISO Phencyclidine results in increased expression of KCNIP3 mRNA CTD PMID:17266109 NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 increases expression ISO Phencyclidine results in increased expression of KCNJ4 mRNA CTD PMID:17266109 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151
JBrowse link
G Kitlg KIT ligand increases expression ISO Phencyclidine results in increased expression of KITL mRNA CTD PMID:12105081 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Lep leptin increases expression ISO Phencyclidine results in increased expression of LEP mRNA CTD PMID:12105081 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lpl lipoprotein lipase increases expression ISO Phencyclidine results in increased expression of LPL mRNA CTD PMID:17266109 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mal mal, T-cell differentiation protein decreases expression ISO Phencyclidine results in decreased expression of MAL mRNA CTD PMID:17266109 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
JBrowse link
G Maob monoamine oxidase B increases expression ISO Phencyclidine results in increased expression of MAOB mRNA CTD PMID:17266109 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 increases expression ISO Phencyclidine results in increased expression of MAPK8IP1 mRNA CTD PMID:17266109 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
JBrowse link
G Mbp myelin basic protein increases expression ISO Phencyclidine results in increased expression of MBP mRNA CTD PMID:17266109 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mobp myelin-associated oligodendrocyte basic protein increases expression ISO Phencyclidine results in increased expression of MOBP mRNA CTD PMID:17266109 NCBI chr 8:119,869,504...119,899,605
Ensembl chr 8:119,869,626...119,899,563
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 affects localization
multiple interactions
ISO Phencyclidine affects the localization of NCF1 protein
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]]; ginsenoside Re inhibits the reaction [Phencyclidine affects the localization of NCF1 protein]; GPX1 protein affects the reaction [Phencyclidine affects the localization of NCF1 protein]
CTD PMID:29037473 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Phencyclidine results in increased expression of NR4A2 mRNA CTD PMID:17266109 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Ntsr1 neurotensin receptor 1 multiple interactions ISO NTSR1 gene affects the reaction [Phencyclidine results in decreased expression of DRD1 protein] CTD PMID:20659557 NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
G P2ry1 purinergic receptor P2Y1 increases expression ISO Phencyclidine results in increased expression of P2RY1 mRNA CTD PMID:12105081 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457
JBrowse link
G Pde10a phosphodiesterase 10A increases expression ISO Phencyclidine results in increased expression of PDE10A mRNA CTD PMID:17266109 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
JBrowse link
G Plp1 proteolipid protein 1 increases expression ISO Phencyclidine results in increased expression of PLP1 mRNA CTD PMID:17266109 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032
JBrowse link
G Prkcd protein kinase C, delta increases expression ISO Phencyclidine results in increased expression of PRKCD mRNA CTD PMID:12105081 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkcg protein kinase C, gamma increases expression EXP Phencyclidine results in increased expression of PRKCG mRNA CTD PMID:11169168 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Ptgds prostaglandin D2 synthase increases expression ISO Phencyclidine results in increased expression of PTGDS mRNA CTD PMID:17266109 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptprcap protein tyrosine phosphatase, receptor type, C-associated protein increases expression ISO Phencyclidine results in increased expression of PTPRCAP mRNA CTD PMID:12105081 NCBI chr 1:201,449,133...201,451,293
Ensembl chr 1:201,449,113...201,451,288
JBrowse link
G Pvalb parvalbumin multiple interactions
decreases expression
EXP Clozapine inhibits the reaction [Phencyclidine results in decreased expression of PVALB mRNA]; Haloperidol inhibits the reaction [Phencyclidine results in decreased expression of PVALB mRNA] CTD PMID:12589379 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
JBrowse link
G Reln reelin decreases expression ISO Phencyclidine results in decreased expression of RELN mRNA CTD PMID:17266109 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression ISO Phencyclidine results in increased expression of RGS4 mRNA CTD PMID:17266109 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rtn4 reticulon 4 increases expression ISO Phencyclidine results in increased expression of RTN4 mRNA CTD PMID:17266109 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO Phencyclidine results in increased expression of SCARB1 mRNA CTD PMID:17205118 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Selplg selectin P ligand increases expression ISO Phencyclidine results in increased expression of SELPLG mRNA CTD PMID:12105081 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585
JBrowse link
G Sema3b semaphorin 3B decreases expression ISO Phencyclidine results in decreased expression of SEMA3B mRNA CTD PMID:17205118 NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO Phencyclidine results in increased expression of SGK1 mRNA CTD PMID:17266109 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Phencyclidine results in increased expression of SLC17A6 mRNA CTD PMID:17266109 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
JBrowse link
G Smad5 SMAD family member 5 decreases expression ISO Phencyclidine results in decreased expression of SMAD5 mRNA CTD PMID:12105081 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634
JBrowse link
G Sod1 superoxide dismutase 1 increases activity
multiple interactions
ISO Phencyclidine results in increased activity of SOD1 protein
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]]; GPX1 protein affects the reaction [Phencyclidine results in increased activity of SOD1 protein]
CTD PMID:29037473 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases activity
multiple interactions
ISO Phencyclidine results in decreased activity of SOD2 protein
acetovanillone inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]; ginsenoside Re inhibits the reaction [GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]]; GPX1 protein affects the reaction [Phencyclidine results in decreased activity of SOD2 protein]
CTD PMID:29037473 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases expression EXP Phencyclidine results in increased expression of SRC mRNA CTD PMID:11249956 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srf serum response factor multiple interactions EXP [Dextroamphetamine co-treated with Phencyclidine] promotes the reaction [SRF protein binds to FOS promoter]; Phencyclidine promotes the reaction [SRF protein binds to FOS promoter] CTD PMID:12510024 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Syn2 synapsin II decreases expression ISO Phencyclidine results in decreased expression of SYN2 mRNA CTD PMID:17266109 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
JBrowse link
G Syt2 synaptotagmin 2 increases expression ISO Phencyclidine results in increased expression of SYT2 mRNA CTD PMID:17266109 NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859
JBrowse link
G Tac1 tachykinin, precursor 1 decreases expression ISO Phencyclidine results in decreased expression of TAC1 mRNA CTD PMID:17266109 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tead4 TEA domain transcription factor 4 decreases expression ISO Phencyclidine results in decreased expression of TEAD4 mRNA CTD PMID:12105081 NCBI chr 4:161,474,122...161,572,837
Ensembl chr 4:161,497,851...161,572,323
JBrowse link
G Th tyrosine hydroxylase multiple interactions
increases expression
ISO Phencyclidine inhibits the reaction [Methamphetamine results in decreased activity of TH protein]
Phencyclidine results in increased expression of TH mRNA
CTD PMID:1381816 PMID:12105081 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tnf tumor necrosis factor multiple interactions
affects expression
EXP Haloperidol affects the reaction [Phencyclidine affects the expression of TNF mRNA] CTD PMID:16478754 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ttr transthyretin decreases expression ISO Phencyclidine results in decreased expression of TTR mRNA CTD PMID:17266109 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta decreases expression ISO Phencyclidine results in decreased expression of YWHAB mRNA CTD PMID:17266109 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
JBrowse link
G Zrsr2-ps1 zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2, pseudogene 1 decreases expression ISO Phencyclidine results in decreased expression of ZRSR2-PS1 mRNA CTD PMID:12105081 NCBI chr14:96,972,651...96,978,364
Ensembl chr14:96,972,580...96,978,891
JBrowse link
pindolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 increases expression
affects binding
increases activity
multiple interactions
ISO
EXP
Pindolol results in increased expression of ADRB1 protein
Pindolol binds to ADRB1 protein
Pindolol results in increased activity of ADRB1 protein
[Pindolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; CGP 20712A affects the reaction [Pindolol results in increased activity of ADRB1 protein]; Pindolol binds to and results in decreased activity of ADRB1 protein; Pindolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Pindolol inhibits the reaction [cyanopindolol binds to ADRB1 protein]
Pindolol binds to and results in decreased activity of ADRB1 protein; Pindolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Pindolol inhibits the reaction [Dihydroalprenolol binds to ADRB1 protein]
CTD PMID:2175014 PMID:2462161 PMID:2888869 PMID:12761341 PMID:14730417 More... NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 decreases expression
affects binding
multiple interactions
ISO
EXP
Pindolol results in decreased expression of ADRB2 protein
Pindolol binds to ADRB2 protein
Pindolol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; Pindolol inhibits the reaction [Dihydroalprenolol binds to ADRB2 protein]
[Pindolol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Pindolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Pindolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Pindolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; Pindolol binds to and results in decreased activity of ADRB2 protein; Pindolol inhibits the reaction [cyanopindolol binds to ADRB2 protein]
CTD PMID:2175014 PMID:2462161 PMID:14730417 PMID:17925438 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions EXP
ISO
Pindolol binds to and results in increased activity of ADRB3 protein
[Pindolol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; Pindolol binds to and results in increased activity of ADRB3 protein; Pindolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]
CTD PMID:1682311 PMID:7815362 PMID:14730417 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Agt angiotensinogen multiple interactions ISO Pindolol inhibits the reaction [REN protein results in increased cleavage of AGT protein] CTD PMID:7104148 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP Pindolol binds to and affects the activity of HTR1A protein; Pindolol binds to and results in decreased activity of HTR1A protein CTD PMID:2207497 PMID:9809859 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B affects binding EXP Pindolol binds to HTR1B protein CTD PMID:11888550 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Pindolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein CTD PMID:17925438 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Pindolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein CTD PMID:17925438 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Prl prolactin multiple interactions ISO
EXP
Pindolol inhibits the reaction [Buspirone results in increased secretion of PRL protein] CTD PMID:18194152 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Ren renin multiple interactions
decreases expression
decreases activity
ISO Pindolol inhibits the reaction [REN protein results in increased cleavage of AGT protein]
Pindolol results in decreased expression of REN protein
Pindolol results in decreased activity of REN protein
CTD PMID:791319 PMID:973972 PMID:7104148 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
piperidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO piperidine analog inhibits the reaction [ACHE protein promotes the reaction [APP protein binds to APP protein]]
piperidine analog results in decreased activity of ACHE protein
CTD PMID:17681794 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO piperidine analog inhibits the reaction [ACHE protein promotes the reaction [APP protein binds to APP protein]]; piperidine analog inhibits the reaction [APP protein binds to APP protein] CTD PMID:17681794 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Bche butyrylcholinesterase decreases activity ISO piperidine analog results in decreased activity of BCHE protein CTD PMID:17681794 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO piperidine inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein] CTD PMID:17706638 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 multiple interactions ISO piperidine inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein] CTD PMID:17706638 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ifng interferon gamma multiple interactions ISO piperidine inhibits the reaction [Cadmium Chloride results in decreased secretion of IFNG protein] CTD PMID:17706638 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il2 interleukin 2 decreases expression
multiple interactions
ISO piperidine analog results in decreased expression of IL2 mRNA
piperidine inhibits the reaction [Cadmium Chloride results in decreased secretion of IL2 protein]
CTD PMID:11859000 PMID:17706638 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases activity ISO
EXP
piperidine analog results in decreased activity of SRD5A1 protein CTD PMID:10896124 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases activity ISO
EXP
piperidine analog results in decreased activity of SRD5A2 protein CTD PMID:10896124 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
pizotifen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Pizotyline results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
propranolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase multiple interactions EXP Propranolol inhibits the reaction [Parathion results in increased expression of AANAT protein] CTD PMID:10685507 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
ISO Propranolol results in increased expression of ABCB1 mRNA
Propranolol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]
CTD PMID:15276086 PMID:16671962 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Ada adenosine deaminase multiple interactions EXP Propranolol promotes the reaction [ADA protein results in decreased susceptibility to Norepinephrine] CTD PMID:7949234 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adm adrenomedullin decreases response to substance EXP Propranolol results in decreased susceptibility to ADM protein CTD PMID:9845272 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
affects response to substance
affects binding
increases activity
increases expression
EXP
ISO
Propranolol binds to and results in decreased activity of ADRB1 protein; Propranolol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Propranolol inhibits the reaction [Dihydroalprenolol binds to ADRB1 protein]
ADRB1 protein polymorphism affects the susceptibility to Propranolol
Propranolol binds to ADRB1 protein
[Propranolol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Propranolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; Propranolol binds to and results in decreased activity of ADRB1 protein; Propranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [CGP 12177 results in increased activity of ADRB1 protein]; Propranolol inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; Propranolol inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRB1 protein]
Propranolol results in increased activity of ADRB1 protein
Propranolol results in increased expression of ADRB1 mRNA
CTD PMID:2462161 PMID:6141285 PMID:9593075 PMID:10372227 PMID:10952688 More... NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 decreases expression
multiple interactions
affects binding
increases expression
ISO
EXP
Propranolol results in decreased expression of ADRB2 mRNA
Propranolol binds to and results in decreased activity of ADRB2 protein; Propranolol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; Propranolol inhibits the reaction [Dihydroalprenolol binds to ADRB2 protein]
Propranolol binds to ADRB2 protein
Propranolol results in increased expression of ADRB2 mRNA
[Propranolol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Propranolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Propranolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Propranolol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [Propranolol co-treated with ADRB2 protein] results in increased expression of GNAS protein; [Propranolol co-treated with ADRB2 protein] results in increased expression of GRK2 protein; Propranolol binds to and results in decreased activity of ADRB2 protein; Propranolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [Albuterol binds to and results in increased activity of ADRB2 protein]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]]; Propranolol inhibits the reaction [carvedilol results in increased phosphorylation of ADRB2 protein]; Propranolol inhibits the reaction [cyanopindolol binds to ADRB2 protein]; Propranolol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein]; Propranolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Propranolol inhibits the reaction [Norepinephrine binds to ADRB2 protein]; Propranolol inhibits the reaction [Terbutaline binds to and results in increased activity of ADRB2 protein]
CTD PMID:2169833 PMID:2462161 PMID:2897299 PMID:6141285 PMID:9593075 More... NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
affects response to substance
ISO Propranolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]
ADRB3 affects the susceptibility to Propranolol
CTD PMID:11159692 PMID:14730417 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Agt angiotensinogen multiple interactions
decreases expression
ISO Propranolol inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Propranolol inhibits the reaction [REN protein results in increased cleavage of AGT protein]
Propranolol inhibits the reaction [AGT protein modified form results in increased abundance of Superoxides]; Propranolol inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]
Propranolol results in decreased expression of AGT protein
CTD PMID:14627 PMID:1653766 PMID:7104148 PMID:7843740 PMID:12606818 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
ISO Propranolol results in decreased phosphorylation of AKT1 protein
ANGPT2 protein inhibits the reaction [Propranolol results in decreased phosphorylation of AKT1 protein]
CTD PMID:30130526 PMID:31838054 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO 1-oleoyl-2-acetoyl-sn-glycerol inhibits the reaction [Propranolol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein]]; Propranolol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein] CTD PMID:18218859 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Amy1 amylase alpha 1 multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 2:201,382,678...201,397,487
Ensembl chr 2:201,382,675...201,397,816
JBrowse link
G Angpt2 angiopoietin 2 decreases expression
multiple interactions
ISO Propranolol results in decreased expression of ANGPT2 mRNA; Propranolol results in decreased expression of ANGPT2 protein
ANGPT2 protein inhibits the reaction [Propranolol results in decreased expression of BCL2 protein]; ANGPT2 protein inhibits the reaction [Propranolol results in decreased expression of MKI67 protein]; ANGPT2 protein inhibits the reaction [Propranolol results in decreased phosphorylation of AKT1 protein]; ANGPT2 protein inhibits the reaction [Propranolol results in increased expression of BAX protein]
CTD PMID:31838054 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Arf6 ADP-ribosylation factor 6 affects localization ISO Propranolol affects the localization of ARF6 protein CTD PMID:16280360 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]] CTD PMID:17925438 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP Propranolol inhibits the reaction [Terbutaline results in increased expression of ATP1A1 mRNA] CTD PMID:9700104 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
increases expression
EXP
ISO
Propranolol results in decreased expression of BAX mRNA
Fat Emulsions, Intravenous inhibits the reaction [Propranolol results in increased expression of BAX protein]
ANGPT2 protein inhibits the reaction [Propranolol results in increased expression of BAX protein]
CTD PMID:11218852 PMID:31838054 PMID:35738838 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
multiple interactions
EXP
ISO
Propranolol results in increased expression of BCL2 mRNA
Propranolol results in decreased expression of BCL2 protein
ANGPT2 protein inhibits the reaction [Propranolol results in decreased expression of BCL2 protein]
CTD PMID:11218852 PMID:31838054 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] CTD PMID:10614985 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
affects activity
EXP Propranolol promotes the reaction [CALCA protein affects the susceptibility to Norepinephrine]
Propranolol affects the activity of CALCA protein
CTD PMID:7906887 PMID:8058111 PMID:10075105 PMID:18055875 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases activity
decreases expression
ISO
EXP
Propranolol results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [Propranolol results in increased cleavage of CASP3 protein]; Fat Emulsions, Intravenous inhibits the reaction [Propranolol results in increased cleavage of CASP3 protein]
Propranolol results in increased activity of CASP3 protein
Palmitic Acid promotes the reaction [Propranolol results in increased activity of CASP3 protein]
Propranolol results in decreased expression of CASP3 mRNA
CTD PMID:11218852 PMID:19106745 PMID:22700542 PMID:35738838 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity ISO Propranolol results in increased activity of CASP7 protein CTD PMID:22700542 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions
ISO
EXP
Propranolol results in increased cleavage of CASP9 protein
Fat Emulsions, Intravenous inhibits the reaction [Propranolol results in increased cleavage of CASP9 protein]
CTD PMID:19106745 PMID:35738838 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Propranolol inhibits the reaction [Epinephrine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein]]
Propranolol inhibits the reaction [Norepinephrine inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]]; Propranolol promotes the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]
CTD PMID:9863660 PMID:12538206 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions ISO Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein] CTD PMID:21177286 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP Propranolol inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein] CTD PMID:15522277 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP Propranolol affects the reaction [Norepinephrine affects the expression of and affects the secretion of CRH protein]; Propranolol inhibits the reaction [acephate results in increased expression of CRH mRNA]; Propranolol inhibits the reaction [acephate results in increased secretion of CRH protein]; Propranolol inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Propranolol inhibits the reaction [methamidophos results in increased secretion of CRH protein] CTD PMID:3497798 PMID:12039681 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO
EXP
Propranolol results in increased expression of CYP1A1 protein
Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]]
Propranolol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
CTD PMID:15618653 PMID:15627480 PMID:15710352 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
increases expression
multiple interactions
ISO
EXP
CYP1A2 protein affects the metabolism of Propranolol
Propranolol results in increased expression of CYP1A2 protein
Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]
CTD PMID:15286053 PMID:15618653 PMID:15710352 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Propranolol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] CTD PMID:22167199 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases oxidation ISO CYP2C9 protein results in increased oxidation of Propranolol CTD PMID:19853591 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases oxidation
affects metabolic processing
ISO CYP2C19 protein results in increased oxidation of Propranolol
CYP2C19 protein affects the metabolism of Propranolol
CTD PMID:15286053 PMID:19853591 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP Propranolol inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin] CTD PMID:19858067 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing
increases oxidation
affects metabolic processing
ISO CYP2D6 protein results in increased metabolism of Propranolol
CYP2D6 protein results in increased oxidation of Propranolol
CYP2D6 protein affects the metabolism of Propranolol
CTD PMID:12464242 PMID:15286053 PMID:19853591 PMID:21184751 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases oxidation ISO CYP3A4 protein results in increased oxidation of Propranolol CTD PMID:19853591 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dll4 delta like canonical Notch ligand 4 decreases expression
multiple interactions
ISO Propranolol results in decreased expression of DLL4 protein
DLL4 protein inhibits the reaction [Propranolol results in decreased expression of MMP2 protein]; DLL4 protein inhibits the reaction [Propranolol results in decreased expression of MMP9 protein]
CTD PMID:30130526 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Dobutamine promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]] CTD PMID:18787115 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein] CTD PMID:15621046 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions EXP [Norepinephrine co-treated with Propranolol] results in increased phosphorylation of ELK1 protein; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of ELK1 protein] CTD PMID:11880281 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP Propranolol results in decreased expression of FAS mRNA CTD PMID:11218852 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression EXP Propranolol results in increased expression of FGF1 mRNA CTD PMID:15264218 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases oxidation ISO FMO2 protein results in increased oxidation of Propranolol CTD PMID:26062974 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO [Norepinephrine co-treated with Propranolol] results in increased expression of FN1 protein CTD PMID:11821714 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Propranolol inhibits the reaction [3-(N-phenylamino)-1,2-propanediol 1,2-dioleoyl ester analog results in increased expression of FOS mRNA]; Propranolol inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of FOS] CTD PMID:7905536 PMID:9748542 PMID:15501433 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions EXP Propranolol inhibits the reaction [Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]]; Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]] CTD PMID:8774452 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gja1 gap junction protein, alpha 1 affects localization EXP Propranolol affects the localization of GJA1 protein CTD PMID:17445419 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gk glycerol kinase decreases activity EXP Propranolol results in decreased activity of GK protein CTD PMID:12736183 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gnas GNAS complex locus increases expression
multiple interactions
EXP
ISO
Propranolol results in increased expression of GNAS mRNA
[Propranolol co-treated with ADRB2 protein] results in increased expression of GNAS protein
CTD PMID:10455254 PMID:20668454 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions
increases expression
decreases expression
ISO [Propranolol co-treated with ADRB2 protein] results in increased expression of GRK2 protein
Propranolol results in increased expression of GRK2 protein
Propranolol results in decreased expression of GRK2 protein
CTD PMID:9788834 PMID:10455254 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation EXP Propranolol results in decreased phosphorylation of GSK3B protein CTD PMID:22982863 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Propranolol inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of HMOX1 mRNA] CTD PMID:19483313 PMID:24929186 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hpca hippocalcin affects localization EXP Propranolol affects the localization of HPCA protein CTD PMID:21078978 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B affects binding EXP Propranolol binds to HTR1B protein CTD PMID:11888550 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Il10 interleukin 10 increases expression EXP Propranolol results in increased expression of IL10 mRNA CTD PMID:16908771 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases secretion
ISO
EXP
Propranolol promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]
Propranolol results in decreased secretion of IL1B protein
CTD PMID:11854442 PMID:16386803 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Propranolol inhibits the reaction [Norepinephrine results in increased expression of IL6 mRNA]; Propranolol inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; Propranolol inhibits the reaction [Ozone results in increased expression of IL6 protein] CTD PMID:12619890 PMID:29247675 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions
decreases expression
ISO Propranolol inhibits the reaction [Epinephrine results in decreased expression of INS protein]
Propranolol results in decreased expression of INS protein
CTD PMID:3019152 PMID:6018752 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 multiple interactions ISO Propranolol results in decreased activity of [KCNH2 protein binds to KCNE2 protein] CTD PMID:15679475 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO Propranolol results in decreased activity of [KCNH2 protein binds to KCNE2 protein]; Propranolol results in decreased activity of [KCNH2 protein binds to KCNH2 protein]
Propranolol results in decreased activity of KCNH2 protein
CTD PMID:15679475 PMID:16314852 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 affects response to substance ISO KCNJ2 gene affects the susceptibility to Propranolol CTD PMID:15028050 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 increases expression ISO Propranolol results in increased expression of KCNJ3 mRNA CTD PMID:15603589 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 affects response to substance ISO KCNQ1 gene affects the susceptibility to Propranolol CTD PMID:15028050 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Lep leptin multiple interactions
increases expression
ISO
EXP
Propranolol inhibits the reaction [Isoproterenol results in decreased secretion of LEP protein]
Propranolol results in increased expression of LEP protein
CTD PMID:11022189 PMID:24250662 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor increases expression EXP Propranolol results in increased expression of LEPR mRNA CTD PMID:24250662 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP Propranolol inhibits the reaction [Norepinephrine results in increased expression of LPL mRNA] CTD PMID:9032464 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
[Propranolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; Propranolol inhibits the reaction [Nicotine results in decreased phosphorylation of MAPK1 protein]; Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein]
4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; [Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein; Cadmium Chloride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; cadmium sulfate inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; diphenyleneiodonium inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; N,N'-bis(salicylideneamino)ethane-manganese(II) inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; oxophenylarsine inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Prazosin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Propranolol inhibits the reaction [Colforsin results in increased activity of MAPK1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK1 protein]
CTD PMID:11093795 PMID:11880281 PMID:17925438 PMID:18448488 PMID:19903766 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
[Propranolol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; Propranolol inhibits the reaction [Nicotine results in decreased phosphorylation of MAPK3 protein]; Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein]
4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; [Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein; Cadmium Chloride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; cadmium sulfate inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; diphenyleneiodonium inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; N,N'-bis(salicylideneamino)ethane-manganese(II) inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; oxophenylarsine inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Prazosin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Propranolol inhibits the reaction [Colforsin results in increased activity of MAPK3 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK3 protein]
CTD PMID:11093795 PMID:11880281 PMID:17925438 PMID:18448488 PMID:19903766 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of MCL1 protein] CTD PMID:19903766 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression
multiple interactions
ISO Propranolol results in decreased expression of MKI67 protein
ANGPT2 protein inhibits the reaction [Propranolol results in decreased expression of MKI67 protein]
CTD PMID:31838054 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions
decreases secretion
ISO Propranolol results in decreased expression of MMP2; Propranolol results in decreased expression of MMP2 mRNA; Propranolol results in decreased expression of MMP2 protein
DLL4 protein inhibits the reaction [Propranolol results in decreased expression of MMP2 protein]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA]
Propranolol results in decreased secretion of MMP2 protein
CTD PMID:20424515 PMID:21042766 PMID:24929186 PMID:30130526 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
decreases secretion
ISO Propranolol results in decreased expression of MMP9; Propranolol results in decreased expression of MMP9 mRNA; Propranolol results in decreased expression of MMP9 protein
DLL4 protein inhibits the reaction [Propranolol results in decreased expression of MMP9 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]; Propranolol inhibits the reaction [Norepinephrine results in increased activity of MMP9 protein]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]
Propranolol results in decreased secretion of MMP9 protein
CTD PMID:16574429 PMID:20424515 PMID:21042766 PMID:24929186 PMID:30130526 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions
increases expression
EXP Propranolol promotes the reaction [Norepinephrine results in increased expression of MYH7 mRNA]; Propranolol promotes the reaction [Phenylephrine results in increased expression of MYH7 mRNA]
Propranolol results in increased expression of MYH7 mRNA
CTD PMID:17592507 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Propranolol affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of NGF mRNA] CTD PMID:2174743 PMID:2853697 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nos3 nitric oxide synthase 3 affects expression EXP Propranolol affects the expression of NOS3 CTD PMID:10889169 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Propranolol results in decreased expression of NOTCH1 protein CTD PMID:30130526 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nppa natriuretic peptide A multiple interactions
affects activity
increases expression
EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Propranolol promotes the reaction [Norepinephrine results in increased expression of NPPA mRNA]; Propranolol promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]
Propranolol affects the activity of NPPA protein modified form
Propranolol results in increased expression of NPPA mRNA
CTD PMID:1363893 PMID:10997724 PMID:17592507 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B affects activity EXP Propranolol affects the activity of NPPB protein modified form CTD PMID:1363893 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Propranolol results in increased activity of NR1I2 protein CTD PMID:28259787 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity
multiple interactions
ISO Propranolol results in increased activity of ODC1 protein
Propranolol inhibits the reaction [Clenbuterol results in increased activity of ODC1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of ODC1 protein]
CTD PMID:2286747 PMID:6284819 PMID:10353628 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Orm1 orosomucoid 1 affects binding EXP propranolol affects binding to Orm1 protein in rat serum RGD PMID:3252025 RGD:2316648 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
JBrowse link
G Penk proenkephalin multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of PENK mRNA] CTD PMID:1363325 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Pln phospholamban multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased phosphorylation of PLN protein] CTD PMID:10997724 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression
ISO [Propranolol co-treated with Prazosin] inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA]; Propranolol inhibits the reaction [Clenbuterol results in increased expression of PPARGC1A mRNA]
Propranolol results in decreased expression of PPARGC1A mRNA
CTD PMID:16513826 PMID:17446185 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prkca protein kinase C, alpha decreases expression EXP Propranolol results in decreased expression of PRKCA protein CTD PMID:20668454 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcd protein kinase C, delta decreases expression EXP Propranolol results in decreased expression of PRKCD protein CTD PMID:20668454 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
ISO Propranolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein]; Propranolol inhibits the reaction [Nicotine results in increased activity of PTGS2 protein]; Propranolol promotes the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein]; Propranolol promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]
Propranolol promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Propranolol results in decreased expression of PTGS2; Propranolol results in decreased expression of PTGS2 mRNA; Propranolol results in decreased expression of PTGS2 protein
CTD PMID:11854442 PMID:12872987 PMID:15210717 PMID:18805435 PMID:20424515 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 multiple interactions EXP Propranolol inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein] CTD PMID:17623046 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882
JBrowse link
G Ren renin multiple interactions
decreases activity
decreases expression
ISO
EXP
Propranolol affects the reaction [Anesthetics, Combined results in increased activity of REN protein]; Propranolol affects the reaction [Nitroprusside promotes the reaction [Anesthetics, Combined results in increased activity of REN protein]]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of REN protein]; Propranolol inhibits the reaction [Nitroprusside results in increased activity of REN protein]; Propranolol inhibits the reaction [REN protein results in increased cleavage of AGT protein]
Propranolol results in decreased activity of REN protein
Propranolol inhibits the reaction [ioxitalamic acid results in increased expression of REN protein]; Propranolol inhibits the reaction [Prazosin results in increased transport of REN protein]; Propranolol inhibits the reaction [Yohimbine results in increased expression of REN protein]
Propranolol results in decreased expression of REN protein
CTD PMID:145319 PMID:200433 PMID:637424 PMID:653302 PMID:791319 More... NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation
multiple interactions
ISO Propranolol results in increased phosphorylation of RPS6KB1 protein
Sirolimus inhibits the reaction [Propranolol results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:16537399 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha multiple interactions EXP Propranolol inhibits the reaction [Terbutaline results in increased expression of SCNN1A mRNA] CTD PMID:9700104 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
JBrowse link
G Serpinf1 serpin family F member 1 increases expression ISO propranolol increases expression of Serpinf1 protein in mononuclear phagocytes RGD PMID:31682714 RGD:27226692 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Propranolol inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Propranolol inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Propranolol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:19740083 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Propranolol inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO Propranolol inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Propranolol inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] CTD PMID:21641380 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Propranolol inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Propranolol inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
JBrowse link
G Slc8a1 solute carrier family 8 member A1 multiple interactions ISO Propranolol inhibits the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein] CTD PMID:15621046 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Propranolol inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] CTD PMID:18448488 PMID:20106947 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Sts steroid sulfatase multiple interactions ISO Propranolol inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link
G Tek TEK receptor tyrosine kinase decreases expression ISO Propranolol results in decreased expression of TEK mRNA; Propranolol results in decreased expression of TEK protein CTD PMID:31838054 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions ISO Propranolol inhibits the reaction [Epinephrine results in decreased expression of THY1]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of THY1]; Propranolol inhibits the reaction [Norepinephrine results in decreased expression of THY1] CTD PMID:7558147 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP Propranolol inhibits the reaction [Dopamine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]; Propranolol inhibits the reaction [Ozone results in increased expression of TNF mRNA]; Propranolol inhibits the reaction [Ozone results in increased expression of TNF protein]; Propranolol promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]
Propranolol results in increased expression of TNF protein
CTD PMID:11752888 PMID:15081246 PMID:29247675 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B increases glucuronidation EXP UGT2B protein results in increased glucuronidation of Propranolol CTD PMID:15801678 NCBI chr14:20,630,572...20,665,062
Ensembl chr14:20,630,250...20,651,776
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions
ISO Propranolol results in decreased expression of VEGFA mRNA; Propranolol results in decreased expression of VEGFA protein
Propranolol inhibits the reaction [Norepinephrine results in increased expression of VEGFA mRNA]
CTD PMID:10788502 PMID:20424515 PMID:30130526 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
propranolol hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 decreases binding EXP propranolol hydrochloride decreases binding to the beta2-adrenergic receptor RGD PMID:12875885 RGD:1598755 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
rasagiline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor multiple interactions
increases expression
ISO Sulfasalazine inhibits the reaction [rasagiline results in increased expression of GDNF protein]
rasagiline results in increased expression of GDNF mRNA; rasagiline results in increased expression of GDNF protein
CTD PMID:14687604 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Maob monoamine oxidase B decreases activity ISO rasagiline results in decreased activity of MAOB protein CTD PMID:21923181 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO rasagiline results in increased localization of and results in increased activity of RELA protein; Sulfasalazine inhibits the reaction [rasagiline results in increased localization of and results in increased activity of RELA protein] CTD PMID:14687604 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
Ro 31-8220 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
decreases expression
ISO Ro 31-8220 inhibits the reaction [5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-monophosphorothioate results in increased expression of ABCA1 mRNA]
Ro 31-8220 results in decreased expression of ABCA1 mRNA
CTD PMID:15037193 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Ro 31-8220 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:16757516 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Ro 31-8220 promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BAX protein] CTD PMID:36925031 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Ro 31-8220 promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of BCL2 protein] CTD PMID:36925031 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP Ro 31-8220 inhibits the reaction [Hexachlorocyclohexane results in increased expression of BCL2L1 protein] CTD PMID:22001173 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO
EXP
Ro 31-8220 results in increased activity of CASP3 protein
Ro 31-8220 inhibits the reaction [Hexachlorocyclohexane results in increased activity of CASP3 protein]; Ro 31-8220 inhibits the reaction [Paraoxon results in increased activity of CASP3 protein]
CTD PMID:17561261 PMID:18054255 PMID:22001173 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO Ro 31-8220 results in increased activity of CASP8 protein CTD PMID:18054255 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Ro 31-8220 inhibits the reaction [Hexachlorocyclohexane results in increased activity of CASP9 protein] CTD PMID:22001173 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO Ro 31-8220 inhibits the reaction [Tretinoin results in increased expression of CD38 mRNA] CTD PMID:21393419 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO
EXP
Ro 31-8220 inhibits the reaction [Formaldehyde results in increased phosphorylation of CREB1 protein]; Ro 31-8220 inhibits the reaction [Tretinoin results in increased phosphorylation of CREB1 protein]
Ro 31-8220 inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein]
CTD PMID:15522277 PMID:16280361 PMID:22138297 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Dpp3 dipeptidylpeptidase 3 multiple interactions ISO Ro 31-8220 inhibits the reaction [DPP3 protein results in increased expression of NQO1 protein] CTD PMID:17360324 NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP Ro 31-8220 inhibits the reaction [EDN1 protein results in increased phosphorylation of JUN protein] CTD PMID:12169099 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egf epidermal growth factor multiple interactions EXP Ro 31-8220 inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Ro 31-8220 inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein] CTD PMID:12947092 PMID:16877402 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Fcer1a Fc epsilon receptor Ia multiple interactions ISO Ro 31-8220 inhibits the reaction [FCER1A protein results in increased expression of IL6 mRNA]; Ro 31-8220 inhibits the reaction [FCER1A protein results in increased expression of TNF mRNA] CTD PMID:16818790 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Ro 31-8220 inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA]
Ro 31-8220 results in decreased expression of FOS mRNA
CTD PMID:11353138 PMID:11568973 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO Ro 31-8220 inhibits the reaction [gingerol results in increased expression of GDF15 protein] CTD PMID:18058799 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP Ro 31-8220 promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of GJA1 protein] CTD PMID:36925031 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Grp gastrin releasing peptide multiple interactions ISO Ro 31-8220 promotes the reaction [GRP protein modified form results in increased chemical synthesis of Inositol Phosphates] CTD PMID:18313772 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases activity ISO Ro 31-8220 results in decreased activity of GSK3B protein CTD PMID:10998351 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Ro 31-8220 inhibits the reaction [Acrolein results in increased expression of HMOX1 mRNA]; Ro 31-8220 inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; Ro 31-8220 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] CTD PMID:18048804 PMID:18357586 PMID:26275128 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions EXP Ro 31-8220 inhibits the reaction [Histamine results in increased expression of HRH1 mRNA] CTD PMID:18360087 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Il11 interleukin 11 multiple interactions ISO Ro 31-8220 inhibits the reaction [Formaldehyde results in increased expression of IL11 mRNA]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL11 mRNA] CTD PMID:22138297 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Ro 31-8220 inhibits the reaction [bufalin results in increased expression of IL1B mRNA]; Ro 31-8220 inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Ro 31-8220 inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:10712238 PMID:11854442 PMID:18054255 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Ro 31-8220 inhibits the reaction [FCER1A protein results in increased expression of IL6 mRNA] CTD PMID:16818790 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions ISO
EXP
Ro 31-8220 inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]
Ro 31-8220 inhibits the reaction [apigenin-6-C-(2''-O-rhamnopyranosyl)-fucopyranoside promotes the reaction [Glucose results in increased secretion of INS1 protein]]
CTD PMID:14511371 PMID:19070612 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO
EXP
Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Ro 31-8220 inhibits the reaction [Cadmium Chloride results in increased expression of JUN mRNA]
Ro 31-8220 results in decreased expression of JUN mRNA
Ro 31-8220 inhibits the reaction [EDN1 protein results in increased phosphorylation of JUN protein]; Ro 31-8220 inhibits the reaction [Phenylephrine results in increased expression of JUN mRNA]
CTD PMID:11353138 PMID:11568973 PMID:12169099 PMID:19002563 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
Ro 31-8220 inhibits the reaction [bufalin results in increased phosphorylation of MAPK1 protein]
Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
Ro 31-8220 inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Ro 31-8220 inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Ro 31-8220 inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:10712238 PMID:12083801 PMID:16877402 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
Ro 31-8220 inhibits the reaction [bufalin results in increased phosphorylation of MAPK3 protein]
Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
Ro 31-8220 inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Ro 31-8220 inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Ro 31-8220 inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:10712238 PMID:12083801 PMID:16877402 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP Ro 31-8220 inhibits the reaction [Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein] CTD PMID:11756236 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP Ro 31-8220 inhibits the reaction [Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK9 protein] CTD PMID:11756236 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO Ro 31-8220 inhibits the reaction [Arachidonic Acid results in increased phosphorylation of MAPT protein] CTD PMID:12605413 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein] CTD PMID:32416088 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO Ro 31-8220 inhibits the reaction [DPP3 protein results in increased expression of NQO1 protein]; Ro 31-8220 inhibits the reaction [SQSTM1 protein results in increased expression of NQO1 protein] CTD PMID:17360324 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nts neurotensin increases activity
multiple interactions
ISO Ro 31-8220 results in increased activity of NTS protein
Ro 31-8220 affects the reaction [NTS protein results in increased chemical synthesis of Inositol Phosphates]; Tetradecanoylphorbol Acetate inhibits the reaction [Ro 31-8220 results in increased activity of NTS protein]
CTD PMID:18313772 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A multiple interactions EXP Ro 31-8220 inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased phosphorylation of PPP1R14A protein] CTD PMID:18986333 NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO
EXP
Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCA protein]
Ro 31-8220 promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of PRKCA protein]
CTD PMID:32416088 PMID:36925031 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCE protein] CTD PMID:32416088 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcg protein kinase C, gamma multiple interactions ISO Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCG protein] CTD PMID:32416088 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Prkci protein kinase C, iota decreases activity ISO Ro 31-8220 results in decreased activity of PRKCI protein CTD PMID:14511371 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Ro 31-8220 inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Ro 31-8220 inhibits the reaction [NCX 4040 results in increased expression of PTGS2 protein]
Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]
CTD PMID:11854442 PMID:19576865 PMID:32416088 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP Ro 31-8220 inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased expression of RHOA protein modified form] CTD PMID:18986333 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rnf187 ring finger protein 187 multiple interactions
decreases stability
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ro 31-8220 results in decreased stability of RNF187 protein] CTD PMID:25851810 NCBI chr10:43,709,493...43,715,392
Ensembl chr10:43,702,357...43,716,157
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 decreases activity EXP Ro 31-8220 results in decreased activity of RPS6KA5 protein CTD PMID:15522277 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO Ro 31-8220 inhibits the reaction [Niacin results in increased expression of SCARB1 mRNA] CTD PMID:15037193 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Sftpb surfactant protein B multiple interactions EXP Ro 31-8220 inhibits the reaction [Adenosine Triphosphate results in increased secretion of SFTPB protein]; Ro 31-8220 inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) results in increased secretion of SFTPB protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SFTPB protein] CTD PMID:11704537 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Sftpc surfactant protein C multiple interactions EXP Ro 31-8220 inhibits the reaction [Adenosine Triphosphate results in increased secretion of SFTPC protein]; Ro 31-8220 inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) results in increased secretion of SFTPC protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SFTPC protein] CTD PMID:11704537 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO Ro 31-8220 inhibits the reaction [SQSTM1 protein results in increased expression of NQO1 protein] CTD PMID:17360324 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Ro 31-8220 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:16757516 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Ro 31-8220 inhibits the reaction [FCER1A protein results in increased expression of TNF mRNA] CTD PMID:16818790 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO Ro 31-8220 inhibits the reaction [decitabine results in increased expression of TNFSF10 protein] CTD PMID:17283156 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression EXP Ro 31-8220 results in decreased expression of VEGFA mRNA CTD PMID:12590138 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
vandetanib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin increases expression
increases expression
ISO vandetanib results in increased expression of ADM mRNA
vandetanib increases expression of ADM mRNA in gastric tumors of human cells in mouse model
CTD
RGD
PMID:16052530 PMID:16052530 RGD:153344579 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
ISO vandetanib results in decreased phosphorylation of AKT1 protein
INS protein inhibits the reaction [vandetanib results in decreased phosphorylation of AKT1 protein]
CTD PMID:23799852 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO vandetanib results in increased expression of ANGPTL4 mRNA CTD PMID:16052530 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO vandetanib results in increased expression of BNIP3L mRNA CTD PMID:16052530 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Calb1 calbindin 1 increases expression ISO vandetanib results in increased expression of CALB1 mRNA CTD PMID:16052530 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [3-methyladenine co-treated with vandetanib] results in increased activity of CASP3 protein; [Chloroquine co-treated with vandetanib] results in increased activity of CASP3 protein CTD PMID:23799852 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [3-methyladenine co-treated with vandetanib] results in increased activity of CASP9 protein; [Chloroquine co-treated with vandetanib] results in increased activity of CASP9 protein CTD PMID:23799852 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Col4a3 collagen type IV alpha 3 chain increases expression ISO vandetanib results in increased expression of COL4A3 mRNA CTD PMID:16052530 NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
multiple interactions
ISO CYP3A4 protein alternative form affects the metabolism of vandetanib
Ketoconazole affects the reaction [CYP3A4 protein alternative form affects the metabolism of vandetanib]
CTD PMID:34648813 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO vandetanib results in increased expression of DUSP1 mRNA CTD PMID:16052530 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Egfr epidermal growth factor receptor affects response to substance
decreases phosphorylation
decreases activity
ISO EGFR affects the susceptibility to vandetanib
vandetanib results in decreased phosphorylation of EGFR protein
vandetanib results in decreased activity of EGFR protein
CTD PMID:15596048 PMID:15604279 PMID:21350000 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation ISO vandetanib results in decreased phosphorylation of EIF4EBP1 protein CTD PMID:23799852 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eno2 enolase 2 increases expression ISO vandetanib results in increased expression of ENO2 mRNA CTD PMID:16052530 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Fam13a family with sequence similarity 13, member A increases expression ISO vandetanib results in increased expression of FAM13A mRNA CTD PMID:16052530 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
JBrowse link
G Gpt glutamic--pyruvic transaminase increases secretion ISO vandetanib results in increased secretion of GPT protein CTD PMID:29655783 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO vandetanib results in increased expression of H1-2 mRNA CTD PMID:16052530 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression ISO vandetanib results in increased expression of HILPDA mRNA CTD PMID:16052530 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO vandetanib results in increased expression of IGFBP1 mRNA CTD PMID:16052530 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression
increases expression
ISO vandetanib results in increased expression of IGFBP3 mRNA
vandetanib increases expression of IGFBP-3 mRNA in gastric tumors of human cells in mouse model
CTD
RGD
PMID:16052530 PMID:16052530 RGD:153344579 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS protein inhibits the reaction [vandetanib results in decreased phosphorylation of AKT1 protein]; INS protein inhibits the reaction [vandetanib results in decreased phosphorylation of RPS6 protein] CTD PMID:23799852 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO vandetanib results in increased expression of INSIG1 mRNA CTD PMID:16052530 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 increases expression ISO vandetanib results in increased expression of INSIG2 mRNA CTD PMID:16052530 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects binding
decreases expression
multiple interactions
ISO vandetanib binds to KCNH2 protein
vandetanib results in decreased expression of KCNH2 protein modified form
Brefeldin A promotes the reaction [vandetanib results in decreased expression of KCNH2 protein modified form]; N-butanoylsphingosine inhibits the reaction [vandetanib results in decreased expression of KCNH2 protein modified form]; vandetanib results in decreased expression of and results in decreased activity of KCNH2 protein
CTD PMID:29630634 PMID:35680041 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO vandetanib results in increased expression of KDM3A mRNA CTD PMID:16052530 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Msh3 mutS homolog 3 decreases expression ISO vandetanib results in decreased expression of MSH3 mRNA CTD PMID:16052530 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Muc1 mucin 1, cell surface associated increases expression ISO vandetanib results in increased expression of MUC1 mRNA CTD PMID:16052530 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO vandetanib results in increased expression of NDRG1 mRNA CTD PMID:16052530 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression ISO vandetanib results in increased expression of PGK1 mRNA CTD PMID:16052530 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression ISO vandetanib results in increased expression of PLOD2 mRNA CTD PMID:16052530 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Ptma prothymosin alpha decreases expression ISO vandetanib results in decreased expression of PTMA mRNA CTD PMID:16052530 NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333
JBrowse link
G Ret ret proto-oncogene decreases phosphorylation ISO vandetanib results in decreased phosphorylation of RET protein CTD PMID:17431108 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation
multiple interactions
ISO vandetanib results in decreased phosphorylation of RPS6 protein
INS protein inhibits the reaction [vandetanib results in decreased phosphorylation of RPS6 protein]
CTD PMID:23799852 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO vandetanib results in increased expression of SCD mRNA CTD PMID:16052530 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO vandetanib results in increased expression of SLC2A3 mRNA CTD PMID:16052530 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO vandetanib results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression ISO vandetanib results in increased expression of TSC22D3 mRNA CTD PMID:16052530 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        NMR chemical shift reference compound 17992
          ammonia 17848
            organic amino compound 17848
              amine 8283
                secondary amine 1842
                  (4E)-3-(benzylamino)-5-phenyl-4-penten-1-ol 0
                  1H-pyrrole + 83
                  3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine 0
                  3-amino-4-(propylamino)cyclobut-3-ene-1,2-dione 0
                  3-methylamino-1,2-propanediol 0
                  5-(methylamino)-3H-1,3,4-thiadiazole-2-thione 0
                  5-methyl-n-(pyridin-3-ylmethyl)isoxazol-3-amine 0
                  Bagrelactone A 0
                  N-(1-deoxy-beta-D-fructopyranos-1-yl)amine(1+) 0
                  N-(3,3-dimethylbutyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine 0
                  N-(cyclohexylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine 0
                  N-methyl-5-pyridin-4-yl-1,3,4-thiadiazol-2-amine 0
                  N-methyl-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine 0
                  N-methylaniline 0
                  PAP + 0
                  alisiaquninone C 0
                  amitivir 0
                  benethamine 0
                  bisoprolol + 15
                  brimonidine + 8
                  diazepinomicin 0
                  dihydromotuporamine C 0
                  dioctylamine 0
                  dobutamine + 77
                  methamphetamine + 1643
                  minaprine + 0
                  nortriptyline 21
                  pindolol + 10
                  piperidine + 106
                  propranolol + 106
                  rasagiline 3
                  secondary aliphatic amine + 6
                  sevadicin 0
                  vandetanib + 36
                  vibegron 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    main group molecular entity 19866
                      s-block molecular entity 19698
                        hydrogen molecular entity 19684
                          hydrides 19159
                            inorganic hydride 18151
                              pnictogen hydride 18140
                                nitrogen hydride 18046
                                  azane 17849
                                    ammonia 17848
                                      organic amino compound 17848
                                        secondary amino compound 6838
                                          secondary amine 1842
                                            (4E)-3-(benzylamino)-5-phenyl-4-penten-1-ol 0
                                            1H-pyrrole + 83
                                            3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine 0
                                            3-amino-4-(propylamino)cyclobut-3-ene-1,2-dione 0
                                            3-methylamino-1,2-propanediol 0
                                            5-(methylamino)-3H-1,3,4-thiadiazole-2-thione 0
                                            5-methyl-n-(pyridin-3-ylmethyl)isoxazol-3-amine 0
                                            Bagrelactone A 0
                                            N-(1-deoxy-beta-D-fructopyranos-1-yl)amine(1+) 0
                                            N-(3,3-dimethylbutyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine 0
                                            N-(cyclohexylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine 0
                                            N-methyl-5-pyridin-4-yl-1,3,4-thiadiazol-2-amine 0
                                            N-methyl-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine 0
                                            N-methylaniline 0
                                            PAP + 0
                                            alisiaquninone C 0
                                            amitivir 0
                                            benethamine 0
                                            bisoprolol + 15
                                            brimonidine + 8
                                            diazepinomicin 0
                                            dihydromotuporamine C 0
                                            dioctylamine 0
                                            dobutamine + 77
                                            methamphetamine + 1643
                                            minaprine + 0
                                            nortriptyline 21
                                            pindolol + 10
                                            piperidine + 106
                                            propranolol + 106
                                            rasagiline 3
                                            secondary aliphatic amine + 6
                                            sevadicin 0
                                            vandetanib + 36
                                            vibegron 0
paths to the root