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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tetracene
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Accession:CHEBI:32600 term browser browse the term
Definition:An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement.
Synonyms:related_synonym: 2,3-benzanthracene;   Formula=C18H12;   InChI=1S/C18H12/c1-2-6-14-10-18-12-16-8-4-3-7-15(16)11-17(18)9-13(14)5-1/h1-12H;   InChIKey=IFLREYGFSNHWGE-UHFFFAOYSA-N;   SMILES=c1ccc2cc3cc4ccccc4cc3cc2c1;   benz[b]anthracene;   naphthacene
 xref: Beilstein:1909299;   CAS:92-24-0;   Gmelin:306993;   PMID:11493061;   PMID:24655187;   Reaxys:1909299;   Wikipedia:Tetracene


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doxorubicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases expression
affects response to substance
multiple interactions
EXP Doxorubicin results in increased expression of ABCB1 protein
ABCB1 protein affects the susceptibility to Doxorubicin
valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]; valspodar inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]
CTD PMID:15492788, PMID:24975508, PMID:28093773 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G HGF hepatocyte growth factor decreases response to substance EXP HGF protein results in decreased susceptibility to Doxorubicin CTD PMID:15688034 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263
JBrowse link
G TNNT2 troponin T2, cardiac type affects expression EXP Doxorubicin affects the expression of TNNT2 protein CTD PMID:12322705 NCBI chr 7:1,598,306...1,620,531
Ensembl chr 7:1,598,306...1,613,741
JBrowse link
G VIP vasoactive intestinal peptide decreases expression EXP Doxorubicin results in decreased expression of VIP protein CTD PMID:3711722 NCBI chr 1:42,941,655...42,950,160
Ensembl chr 1:42,941,224...42,950,700
JBrowse link
G XIAP X-linked inhibitor of apoptosis affects response to substance EXP XIAP affects the susceptibility to Doxorubicin CTD PMID:16953886 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 227
    role 227
      biological role 227
        aetiopathogenetic role 145
          carcinogenic agent 14
            polycyclic arene 8
              ortho-fused polycyclic arene 8
                acene 5
                  tetracene 5
                    (13R)-13-dihydrocarminomycin 0
                    13-deoxycarminomycin 0
                    13-deoxydaunorubicin 0
                    13-dihydrodaunorubicin + 0
                    carminomycin + 0
                    daunorubicin + 0
                    doxorubicin + 5
                    doxorubicinol 0
                    idarubicin 0
                    tetracenecarboxylate ester + 0
                    tetracyclines + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 227
    subatomic particle 227
      composite particle 227
        hadron 227
          baryon 227
            nucleon 227
              atomic nucleus 227
                atom 227
                  main group element atom 220
                    main group molecular entity 220
                      s-block molecular entity 174
                        hydrogen molecular entity 172
                          hydrides 114
                            organic hydride 60
                              organic fundamental parent 60
                                hydrocarbon 37
                                  cyclic hydrocarbon 14
                                    arene 13
                                      polycyclic arene 8
                                        ortho-fused polycyclic arene 8
                                          acene 5
                                            tetracene 5
                                              (13R)-13-dihydrocarminomycin 0
                                              13-deoxycarminomycin 0
                                              13-deoxydaunorubicin 0
                                              13-dihydrodaunorubicin + 0
                                              carminomycin + 0
                                              daunorubicin + 0
                                              doxorubicin + 5
                                              doxorubicinol 0
                                              idarubicin 0
                                              tetracenecarboxylate ester + 0
                                              tetracyclines + 0
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