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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:32347 term browser browse the term
Definition:A biguanide that has formula C8H10ClN5.
Synonyms:related_synonym: Formula=C8H10ClN5;   InChI=1S/C8H10ClN5/c9-5-2-1-3-6(4-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14);   InChIKey=DIHXJZHAIHGSAW-UHFFFAOYSA-N;   SMILES=NC(=N)NC(=N)Nc1cccc(Cl)c1;   mCPBG
 xref: CAS:48144-44-1;   KEGG:C13646;   LINCS:LSM-2812
 xref_mesh: MESH:C065734

show annotations for term's descendants           Sort by:
m-Chlorophenylbiguanide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP 1-(3-chlorophenyl)biguanide results in increased expression of FOS protein CTD PMID:12088752 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions
decreases expression
EXP BESEB CDRI-08 inhibits the reaction [1-(3-chlorophenyl)biguanide results in decreased expression of HTR3A mRNA] CTD PMID:21735137 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        pharmaceutical 19624
          drug 19655
            hypoglycemic agent 4149
              biguanides 446
                m-Chlorophenylbiguanide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                carbocyclic compound 18542
                                  benzenoid aromatic compound 17766
                                    benzenes 17590
                                      chlorobenzenes 13873
                                        monochlorobenzenes 9902
                                          m-Chlorophenylbiguanide 2
paths to the root