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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:32347 term browser browse the term
Definition:A biguanide that has formula C8H10ClN5.
Synonyms:related_synonym: Formula=C8H10ClN5;   InChI=1S/C8H10ClN5/c9-5-2-1-3-6(4-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14);   InChIKey=DIHXJZHAIHGSAW-UHFFFAOYSA-N;   SMILES=NC(=N)NC(=N)Nc1cccc(Cl)c1;   mCPBG
 xref: CAS:48144-44-1;   KEGG:C13646;   LINCS:LSM-2812
 xref_mesh: MESH:C065734

show annotations for term's descendants           Sort by:
m-Chlorophenylbiguanide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP 1-(3-chlorophenyl)biguanide results in increased expression of FOS protein CTD PMID:12088752 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions
decreases expression
EXP BESEB CDRI-08 inhibits the reaction [1-(3-chlorophenyl)biguanide results in decreased expression of HTR3A mRNA] CTD PMID:21735137 NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        pharmaceutical 19272
          drug 19272
            hypoglycemic agent 4030
              biguanides 440
                m-Chlorophenylbiguanide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                carbocyclic compound 18181
                                  benzenoid aromatic compound 17178
                                    benzenes 16920
                                      chlorobenzenes 12990
                                        monochlorobenzenes 8871
                                          m-Chlorophenylbiguanide 2
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.