Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:32316 term browser browse the term
Definition:A dibenzothiepine that has formula C18H18ClNOS.
Synonyms:exact_synonym: 2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine
 related_synonym: 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin;   2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin;   Formula=C18H18ClNOS;   InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3;   InChIKey=HDOZVRUNCMBHFH-UHFFFAOYSA-N;   Lodopin;   SMILES=CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12;   Setous;   zotepina;   zotepinum
 xref: Beilstein:1435710;   CAS:26615-21-4;   Drug_Central:2875;   KEGG:D01321;   LINCS:LSM-6636
 xref_mesh: MESH:C022172
 xref: Patent:DE1907670;   Patent:US3704245

show annotations for term's descendants           Sort by:
zotepine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin decreases expression ISO zotepine results in decreased expression of PRL protein CTD PMID:18063941 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      biological role 19720
        pharmacological role 18830
          neurotransmitter agent 16444
            serotonergic drug 3974
              zotepine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    main group molecular entity 19662
                      s-block molecular entity 19429
                        hydrogen molecular entity 19423
                          hydrides 18758
                            inorganic hydride 17453
                              pnictogen hydride 17428
                                nitrogen hydride 17272
                                  azane 17003
                                    ammonia 17002
                                      organic amino compound 17001
                                        tertiary amino compound 8648
                                          zotepine 1
paths to the root