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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:32316 term browser browse the term
Definition:A dibenzothiepine that has formula C18H18ClNOS.
Synonyms:exact_synonym: 2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine
 related_synonym: 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin;   2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin;   Formula=C18H18ClNOS;   InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3;   InChIKey=HDOZVRUNCMBHFH-UHFFFAOYSA-N;   Lodopin;   SMILES=CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12;   Setous;   zotepina;   zotepinum
 xref: Beilstein:1435710;   CAS:26615-21-4;   Drug_Central:2875;   KEGG:D01321;   LINCS:LSM-6636
 xref_mesh: MESH:C022172
 xref: Patent:DE1907670;   Patent:US3704245

show annotations for term's descendants           Sort by:
zotepine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin decreases expression ISO zotepine results in decreased expression of PRL protein CTD PMID:18063941 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      biological role 19825
        pharmacological role 18870
          neurotransmitter agent 16469
            serotonergic drug 3969
              zotepine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    main group molecular entity 19763
                      s-block molecular entity 19511
                        hydrogen molecular entity 19503
                          hydrides 18775
                            inorganic hydride 17505
                              pnictogen hydride 17478
                                nitrogen hydride 17323
                                  azane 17040
                                    ammonia 17039
                                      organic amino compound 17038
                                        tertiary amino compound 8652
                                          zotepine 1
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