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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:32315 term browser browse the term
Definition:A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Synonyms:exact_synonym: 6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
 related_synonym: 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate;   Formula=C17H17ClN6O3;   InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3;   InChIKey=GBBSUAFBMRNDJC-UHFFFAOYSA-N;   SMILES=CN1CCN(CC1)C(=O)OC1N(C(=O)c2nccnc12)c1ccc(Cl)cn1;   zopiclona;   zopiclonum
 xref: Beilstein:768704;   CAS:43200-80-2;   DrugBank:DB01198;   Drug_Central:2873;   KEGG:D01372;   LINCS:LSM-4408
 xref_mesh: MESH:C515050
 xref: Patent:DE2300491;   Patent:US3862149;   Wikipedia:Zopiclone

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zopiclone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases metabolic processing ISO CYP2C8 protein results in increased metabolism of zopiclone CTD PMID:12464242 NCBI chr 1:147,236,480...147,307,988 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        pharmaceutical 19293
          drug 19293
            central nervous system drug 16449
              central nervous system depressant 16004
                zopiclone 1
                  (5R)-zopiclone 0
                  eszopiclone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  organic heteromonocyclic compound 16467
                                    pyridines 8390
                                      chloropyridine 1000
                                        monochloropyridine 138
                                          zopiclone 1
                                            (5R)-zopiclone 0
                                            eszopiclone 0
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