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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:butamben
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Accession:CHEBI:3231 term browser browse the term
Definition:An amino acid ester resulting from the formal condensation of the carboxy group of 4-aminobenzoic acid with the hydroxy group of butan-1-ol. Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders.
Synonyms:exact_synonym: butyl 4-aminobenzoate
 related_synonym: 4-(butoxycarbonyl)aniline;   4-aminobenzoic acid butyl ester;   BAB;   Butesin;   Butoform;   Formula=C11H15NO2;   InChI=1S/C11H15NO2/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7H,2-3,8,12H2,1H3;   InChIKey=IUWVALYLNVXWKX-UHFFFAOYSA-N;   Planoform;   SMILES=CCCCOC(=O)c1ccc(N)cc1;   Scuroform;   Scuroforme;   butyl aminobenzoate;   butyl p-aminobenzoate;   n-butyl p-aminobenzoate;   p-aminobenzoic acid butyl ester
 xref: CAS:94-25-7;   Drug_Central:3051;   KEGG:C07875;   KEGG:D00730;   LINCS:LSM-5413
 xref_mesh: MESH:C004605
 xref: PMID:15920194;   PMID:15923341;   PMID:16368819;   PMID:18499609;   PMID:22133806;   PMID:2393134;   PMID:24486399;   PMID:7793660;   PMID:9009953;   PMID:9690593;   Patent:GB252870;   Patent:US1440652;   Reaxys:1211465;   Wikipedia:Butamben
 cyclic_relationship: is_conjugate_base_of CHEBI:86302


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butamben term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP butamben binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to MED1 protein]; butamben promotes the reaction [NR1I2.S protein binds to MED1 protein] CTD PMID:12198127 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA1 protein]; butamben promotes the reaction [NR1I2.S protein binds to NCOA1 protein] CTD PMID:12198127 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA2 protein] CTD PMID:12198127 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA3 protein] CTD PMID:12198127 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        aetiopathogenetic role 19044
          allergen 17271
            4-aminobenzoic acid 26
              butamben 5
                butamben picrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        aromatic carboxylic acid 11710
                                          benzoic acids 11683
                                            aminobenzoic acid 1627
                                              4-aminobenzoic acid 26
                                                butamben 5
                                                  butamben picrate 0
paths to the root