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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:butamben
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Accession:CHEBI:3231 term browser browse the term
Definition:An amino acid ester resulting from the formal condensation of the carboxy group of 4-aminobenzoic acid with the hydroxy group of butan-1-ol. Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders.
Synonyms:exact_synonym: butyl 4-aminobenzoate
 related_synonym: 4-(butoxycarbonyl)aniline;   4-aminobenzoic acid butyl ester;   BAB;   Butesin;   Butoform;   Formula=C11H15NO2;   InChI=1S/C11H15NO2/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7H,2-3,8,12H2,1H3;   InChIKey=IUWVALYLNVXWKX-UHFFFAOYSA-N;   Planoform;   SMILES=CCCCOC(=O)c1ccc(N)cc1;   Scuroform;   Scuroforme;   butyl aminobenzoate;   butyl p-aminobenzoate;   n-butyl p-aminobenzoate;   p-aminobenzoic acid butyl ester
 xref: CAS:94-25-7;   Drug_Central:3051;   KEGG:C07875;   KEGG:D00730;   LINCS:LSM-5413
 xref_mesh: MESH:C004605
 xref: PMID:15920194;   PMID:15923341;   PMID:16368819;   PMID:18499609;   PMID:22133806;   PMID:2393134;   PMID:24486399;   PMID:7793660;   PMID:9009953;   PMID:9690593;   Patent:GB252870;   Patent:US1440652;   Reaxys:1211465;   Wikipedia:Butamben
 cyclic_relationship: is_conjugate_base_of CHEBI:86302


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butamben term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP butamben binds to AR protein CTD PMID:14565775 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to MED1 protein]; butamben promotes the reaction [NR1I2.S protein binds to MED1 protein] CTD PMID:12198127 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA1 protein]; butamben promotes the reaction [NR1I2.S protein binds to NCOA1 protein] CTD PMID:12198127 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA2 protein] CTD PMID:12198127 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO butamben promotes the reaction [NR1I2.L protein binds to NCOA3 protein] CTD PMID:12198127 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        aetiopathogenetic role 18960
          allergen 16942
            4-aminobenzoic acid 26
              butamben 5
                butamben picrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        aromatic carboxylic acid 10898
                                          benzoic acids 10867
                                            aminobenzoic acid 1614
                                              4-aminobenzoic acid 26
                                                butamben 5
                                                  butamben picrate 0
paths to the root

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