CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Voglibose
Accession: CHEBI:32300
browse the term
Synonyms: related_synonym: 3,4-Dideoxy-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-C-(hydroxymethyl)-D-epi-inositol; AO-128; Basen (TN); Formula=C10H21NO7; InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7-,8+,9-,10-/m0/s1; InChIKey=FZNCGRZWXLXZSZ-CIQUZCHMSA-N; SMILES=N(C(CO)CO)[C@H]1C[C@@](CO)(O)[C@H]([C@@H]([C@H]1O)O)O; glustat; voglistat
xref: CAS:83480-29-9; Drug_Central:2845; HMDB:HMDB0015598; KEGG:D01665
xref_mesh: MESH:C102817
G
Alpi
alkaline phosphatase, intestinal
increases activity
EXP
voglibose results in increased activity of ALPI protein
CTD
PMID:12560160
NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
G
Dpp4
dipeptidylpeptidase 4
multiple interactions
ISO
voglibose results in decreased expression of and results in decreased activity of DPP4 protein
CTD
PMID:19208898
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Gcg
glucagon
increases expression increases secretion
ISO
voglibose results in increased expression of GCG mRNA; voglibose results in increased expression of GCG protein voglibose results in increased secretion of GCG protein
CTD
PMID:19208898
NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
G
Ins1
insulin 1
decreases secretion
ISO EXP
voglibose results in decreased secretion of INS1 protein
CTD
PMID:12560160 PMID:19208898
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
G
Neurod1
neuronal differentiation 1
increases expression
ISO
voglibose results in increased expression of NEUROD1 mRNA
CTD
PMID:19208898
NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649
G
Si
sucrase-isomaltase
decreases activity
EXP
voglibose results in decreased activity of SI protein
CTD
PMID:12560160
NCBI chr 2:157,505,893...157,586,228
Ensembl chr 2:157,506,342...157,585,260
G
Treh
trehalase
increases activity
EXP
voglibose results in increased activity of TREH protein
CTD
PMID:12560160
NCBI chr 8:44,990,182...45,003,881
Ensembl chr 8:44,990,182...45,003,540
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