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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:butachlor
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Accession:CHEBI:3230 term browser browse the term
Definition:An aromatic amide that is 2-choro-N-(2,6-diethylphenyl)acetamide in which the amide nitrogen has been replaced by a butoxymethyl group.
Synonyms:exact_synonym: N-(butoxymethyl)-2-chloro-N-(2,6-diethylphenyl)acetamide
 related_synonym: 2',6'-Diethyl-N-butoxymethyl-2-chloroacetanilide;   2',6'-Diethyl-N-butoxymethyl-alpha-chloroacetanilide;   2-Chloro-2',6'-diethyl-N-(butoxymethyl)acetanilide;   Formula=C17H26ClNO2;   InChI=1S/C17H26ClNO2/c1-4-7-11-21-13-19(16(20)12-18)17-14(5-2)9-8-10-15(17)6-3/h8-10H,4-7,11-13H2,1-3H3;   InChIKey=HKPHPIREJKHECO-UHFFFAOYSA-N;   N-(Butoxymethyl)-2-chloro-2',6'-diethylacetanilide;   N-Butoxymethyl-alpha-chloro-2',6'-diethylacetanilide;   SMILES=C1=CC=C(C(=C1CC)N(COCCCC)C(CCl)=O)CC
 xref: AGR:IND601190844;   CAS:23184-66-9;   KEGG:C10931
 xref_mesh: MESH:C054409
 xref: MetaCyc:CPD-18941;   PMID:20183093;   PMID:25097380;   PMID:25378033;   PMID:25528421;   PMID:25708297;   PMID:25763539;   PMID:26027538;   PMID:26368393;   PMID:26372161;   PMID:26461443;   PMID:26946506;   PMID:26971167;   PMID:27071456;   PMID:27182978;   PMID:27419617;   PMID:27480594;   PMID:27514993;   PMID:27522569;   PMID:27579872;   PMID:27943158;   PMID:27974272;   PMID:27987462;   PMID:28045224;   PMID:28190210;   PPDB:101;   Reaxys:2873811


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butachlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin increases expression ISO butachlor results in increased expression of ALB protein CTD PMID:34351278 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 decreases expression ISO butachlor results in decreased expression of APAF1 mRNA CTD PMID:34351278 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433 		JBrowse link
G AR androgen receptor increases activity EXP butachlor results in increased activity of AR protein CTD PMID:20143881 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ATG5 autophagy related 5 increases expression
decreases expression		 ISO butachlor results in increased expression of ATG5 protein
butachlor results in decreased expression of ATG5 mRNA		 CTD PMID:34351278 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G CASP3 caspase 3 decreases expression ISO butachlor results in decreased expression of CASP3 mRNA CTD PMID:34351278 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 decreases expression ISO butachlor results in decreased expression of CASP9 mRNA CTD PMID:34351278 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CYCS cytochrome c, somatic decreases expression ISO butachlor results in decreased expression of CYCS mRNA CTD PMID:34351278 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 increases metabolic processing EXP CYP2B6 protein results in increased metabolism of butachlor CTD PMID:11133395 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases metabolic processing EXP CYP3A4 protein results in increased metabolism of butachlor CTD PMID:11133395 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G DIO1 iodothyronine deiodinase 1 decreases activity EXP butachlor results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086 		JBrowse link
G IL10 interleukin 10 decreases expression ISO butachlor results in decreased expression of IL10 mRNA CTD PMID:34351278 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases expression ISO butachlor results in increased expression of MAP1LC3B protein CTD PMID:34351278 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MTOR mechanistic target of rapamycin kinase decreases expression ISO butachlor results in decreased expression of MTOR mRNA CTD PMID:34351278 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 increases activity EXP butachlor results in increased activity of NR1H4 protein CTD PMID:20143881 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 increases activity EXP butachlor results in increased activity of NR3C1 protein CTD PMID:20143881 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G SQSTM1 sequestosome 1 decreases expression ISO butachlor results in decreased expression of SQSTM1 mRNA; butachlor results in decreased expression of SQSTM1 protein CTD PMID:34351278 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G THRB thyroid hormone receptor beta affects binding EXP butachlor binds to THRB protein CTD PMID:28973306 NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756 		JBrowse link
G TNF tumor necrosis factor decreases expression ISO butachlor results in decreased expression of TNF mRNA CTD PMID:34351278 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      biological role 25929
        xenobiotic 20368
          butachlor 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    main group molecular entity 25834
                      s-block molecular entity 25166
                        hydrogen molecular entity 24765
                          hydrides 22965
                            inorganic hydride 20483
                              pnictogen hydride 20424
                                nitrogen hydride 20200
                                  azane 19942
                                    ammonia 19941
                                      organic amino compound 19941
                                        primary amino compound 9935
                                          primary amine 6517
                                            primary arylamine 3882
                                              aniline 3681
                                                anilide 1154
                                                  N-phenylacetamide 228
                                                    butachlor 18
paths to the root