CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: butachlor
Accession: CHEBI:3230
browse the term
Definition: An aromatic amide that is 2-choro-N-(2,6-diethylphenyl)acetamide in which the amide nitrogen has been replaced by a butoxymethyl group.
Synonyms: exact_synonym: N-(butoxymethyl)-2-chloro-N-(2,6-diethylphenyl)acetamide
related_synonym: 2',6'-Diethyl-N-butoxymethyl-2-chloroacetanilide; 2',6'-Diethyl-N-butoxymethyl-alpha-chloroacetanilide; 2-Chloro-2',6'-diethyl-N-(butoxymethyl)acetanilide; Formula=C17H26ClNO2; InChI=1S/C17H26ClNO2/c1-4-7-11-21-13-19(16(20)12-18)17-14(5-2)9-8-10-15(17)6-3/h8-10H,4-7,11-13H2,1-3H3; InChIKey=HKPHPIREJKHECO-UHFFFAOYSA-N; N-(Butoxymethyl)-2-chloro-2',6'-diethylacetanilide; N-Butoxymethyl-alpha-chloro-2',6'-diethylacetanilide; SMILES=C1=CC=C(C(=C1CC)N(COCCCC)C(CCl)=O)CC
xref: AGR:IND601190844; CAS:23184-66-9; KEGG:C10931
xref_mesh: MESH:C054409
xref: MetaCyc:CPD-18941; PMID:20183093; PMID:25097380; PMID:25378033; PMID:25528421; PMID:25708297; PMID:25763539; PMID:26027538; PMID:26368393; PMID:26372161; PMID:26461443; PMID:26946506; PMID:26971167; PMID:27071456; PMID:27182978; PMID:27419617; PMID:27480594; PMID:27514993; PMID:27522569; PMID:27579872; PMID:27943158; PMID:27974272; PMID:27987462; PMID:28045224; PMID:28190210; PPDB:101; Reaxys:2873811
G
Ar
androgen receptor
increases activity
ISO
butachlor results in increased activity of AR protein
CTD
PMID:20143881
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases metabolic processing
ISO
CYP2B6 protein results in increased metabolism of butachlor
CTD
PMID:11133395
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases metabolic processing
ISO
CYP3A4 protein results in increased metabolism of butachlor
CTD
PMID:11133395
NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
G
Dio1
iodothyronine deiodinase 1
decreases activity
ISO
butachlor results in decreased activity of DIO1 protein
CTD
PMID:29228274
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
G
Nr1h4
nuclear receptor subfamily 1, group H, member 4
increases activity
ISO
butachlor results in increased activity of NR1H4 protein
CTD
PMID:20143881
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
increases activity
ISO
butachlor results in increased activity of NR3C1 protein
CTD
PMID:20143881
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Thrb
thyroid hormone receptor beta
affects binding
ISO
butachlor binds to THRB protein
CTD
PMID:28973306
NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all