|
G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
multiple interactions |
EXP |
Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of ACSL4 protein]] |
CTD |
PMID:35093381 |
|
NCBI chr X:110,739,633...110,803,416
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|
G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]] |
CTD |
PMID:38992766 |
|
NCBI chr 1:241,159,723...241,172,503
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|
G |
Amotl1 |
angiomotin-like 1 |
multiple interactions decreases response to substance |
ISO |
Verteporfin inhibits the reaction [AMOTL1 protein results in increased activity of YAP1 protein] Verteporfin results in decreased susceptibility to AMOTL1 protein |
CTD |
PMID:34480788 |
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NCBI chr 8:11,348,651...11,467,564
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|
G |
Ankrd1 |
ankyrin repeat domain 1 |
multiple interactions decreases expression |
ISO |
verteporfin inhibits the reaction [YAP1 protein results in increased expression of ANKRD1 mRNA] verteporfin results in decreased expression of ANKRD1 mRNA [calcipotriene co-treated with Verteporfin] promotes the reaction [Carbon Tetrachloride results in increased expression of ANKRD1 mRNA]; Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ANKRD1 mRNA]; Verteporfin promotes the reaction [Carbon Tetrachloride results in increased expression of ANKRD1 mRNA] |
CTD |
PMID:29725256 PMID:29893953 PMID:38992766 |
|
NCBI chr 1:233,815,851...233,834,891
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|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of BAX protein]] |
CTD |
PMID:35093381 |
|
NCBI chr 1:105,076,472...105,081,906
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|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
EXP |
Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]] |
CTD |
PMID:35093381 |
|
NCBI chr13:23,204,464...23,366,900
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|
G |
Birc5 |
baculoviral IAP repeat-containing 5 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of BIRC5 mRNA] |
CTD |
PMID:29893953 |
|
NCBI chr10:103,567,369...103,580,069
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|
G |
Casp9 |
caspase 9 |
multiple interactions |
EXP |
Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in decreased expression of and results in increased cleavage of CASP9 protein]] |
CTD |
PMID:35093381 |
|
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL2 protein] |
CTD |
PMID:31812773 |
|
NCBI chr10:67,503,077...67,504,875
|
|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL5 protein] |
CTD |
PMID:31812773 |
|
NCBI chr10:68,820,330...68,824,906
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|
G |
Ccn1 |
cellular communication network factor 1 |
multiple interactions decreases expression |
ISO |
Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN1 mRNA] Verteporfin results in decreased expression of CCN1 mRNA Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCN1 mRNA] |
CTD |
PMID:29725256 PMID:29893953 |
|
NCBI chr 2:234,562,410...234,565,370
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|
G |
Ccn2 |
cellular communication network factor 2 |
decreases expression multiple interactions |
ISO |
Verteporfin results in decreased expression of CCN2 mRNA Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN2 mRNA] [calcipotriene co-treated with Verteporfin] promotes the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA]; Verteporfin inhibits the reaction [[XMU-MP-1 co-treated with Cadmium Chloride] results in increased expression of CCN2 mRNA]; Verteporfin promotes the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] |
CTD |
PMID:29725256 PMID:35027733 PMID:38992766 |
|
NCBI chr 1:22,621,498...22,624,614
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|
G |
Ccna2 |
cyclin A2 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 mRNA] |
CTD |
PMID:29893953 |
|
NCBI chr 2:121,355,363...121,361,762
|
|
G |
Ccnb1 |
cyclin B1 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNB1 mRNA] |
CTD |
PMID:29893953 |
|
NCBI chr 2:33,646,252...33,655,225
|
|
G |
Cdc20 |
cell division cycle 20 |
multiple interactions |
ISO |
[Verteporfin co-treated with calcipotriene] inhibits the reaction [Carbon Tetrachloride results in increased expression of CDC20 mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of CDC20 mRNA] |
CTD |
PMID:38992766 |
|
NCBI chr 5:137,251,596...137,255,799
|
|
G |
Cdc6 |
cell division cycle 6 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of CDC6 mRNA]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of CDC6 mRNA] |
CTD |
PMID:38992766 |
|
NCBI chr10:84,360,361...84,374,239
|
|
G |
Cma1 |
chymase 1 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CMA1 protein] |
CTD |
PMID:31812773 |
|
NCBI chr15:33,387,351...33,390,133
|
|
G |
Cnn2 |
calponin 2 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of CNN2 mRNA]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of CNN2 mRNA] |
CTD |
PMID:38992766 |
|
NCBI chr 7:9,712,505...9,719,678
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
[calcipotriene co-treated with Verteporfin] inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]; Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA] |
CTD |
PMID:38992766 |
|
NCBI chr10:80,380,458...80,397,461
|
|
G |
Csf3 |
colony stimulating factor 3 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CSF3 protein] |
CTD |
PMID:31812773 |
|
NCBI chr10:84,157,485...84,159,860
|
|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP2B10 mRNA] |
CTD |
PMID:29893953 |
|
NCBI chr 1:90,780,468...90,859,852
|
|
G |
Cyp2c24 |
cytochrome P450, family 2, subfamily c, polypeptide 24 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP2C55 mRNA] |
CTD |
PMID:29893953 |
|
NCBI chr 1:236,873,967...236,936,238
|
|
G |
Fundc1 |
FUN14 domain containing 1 |
multiple interactions |
EXP |
Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of FUNDC1 protein]] |
CTD |
PMID:35093381 |
|
NCBI chr X:5,083,635...5,100,293
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
decreases expression |
ISO |
Verteporfin results in decreased expression of GCLC protein |
CTD |
PMID:37832483 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of GPT protein]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein] |
CTD |
PMID:38992766 |
|
NCBI chr 7:110,295,599...110,300,134
|
|
G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions decreases expression |
EXP ISO |
Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in decreased expression of GPX4 protein]] Verteporfin results in decreased expression of GPX4 protein |
CTD |
PMID:35093381 PMID:37832483 |
|
NCBI chr 7:10,300,833...10,303,629
|
|
G |
Gsr |
glutathione-disulfide reductase |
decreases expression |
ISO |
Verteporfin results in decreased expression of GSR protein |
CTD |
PMID:37832483 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Hmmr |
hyaluronan-mediated motility receptor |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [calcipotriene promotes the reaction [Carbon Tetrachloride results in increased expression of HMMR mRNA]]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of HMMR mRNA] |
CTD |
PMID:38992766 |
|
NCBI chr10:25,635,249...25,665,389
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
verteporfin results in increased expression of HMOX1 protein |
CTD |
PMID:16462769 |
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Il11 |
interleukin 11 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL11 mRNA]; Verteporfin promotes the reaction [calcipotriene inhibits the reaction [Carbon Tetrachloride results in increased expression of IL11 mRNA]] |
CTD |
PMID:38992766 |
|
NCBI chr 1:69,069,829...69,076,129
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[EVP 4593 co-treated with Verteporfin] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA] Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein] |
CTD |
PMID:31812773 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Iqgap3 |
IQ motif containing GTPase activating protein 3 |
multiple interactions |
ISO |
[Verteporfin co-treated with calcipotriene] inhibits the reaction [Carbon Tetrachloride results in increased expression of IQGAP3 mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of IQGAP3 mRNA] |
CTD |
PMID:38992766 |
|
NCBI chr 2:173,542,151...173,583,956
|
|
G |
Jak1 |
Janus kinase 1 |
multiple interactions decreases expression |
ISO |
[Verteporfin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of JAK1 protein Verteporfin results in decreased expression of JAK1 protein |
CTD |
PMID:31812773 |
|
NCBI chr 5:120,895,606...121,004,207
|
|
G |
Jak2 |
Janus kinase 2 |
decreases expression multiple interactions |
ISO |
Verteporfin results in decreased expression of JAK2 protein [Verteporfin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of JAK2 protein |
CTD |
PMID:31812773 |
|
NCBI chr 1:236,408,905...236,468,769
|
|
G |
Mcm2 |
minichromosome maintenance complex component 2 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of MCM2 mRNA] |
CTD |
PMID:29893953 |
|
NCBI chr 4:122,903,679...122,918,205
|
|
G |
Mki67 |
marker of proliferation Ki-67 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [[calcipotriene co-treated with Carbon Tetrachloride] results in increased expression of MKI67 mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of MKI67 mRNA]; Verteporfin inhibits the reaction [perfluorooctanoic acid results in increased expression of MKI67 protein] |
CTD |
PMID:36152675 PMID:38992766 |
|
NCBI chr 1:199,926,150...199,952,847
|
|
G |
Mt1 |
metallothionein 1 |
multiple interactions |
ISO |
[Verteporfin co-treated with XMU-MP-1] promotes the reaction [Cadmium Chloride results in increased expression of MT1 mRNA] |
CTD |
PMID:35027733 |
|
NCBI chr19:10,831,959...10,832,975
|
|
G |
Mt2A |
metallothionein 2A |
multiple interactions |
ISO |
[Verteporfin co-treated with XMU-MP-1] promotes the reaction [Cadmium Chloride results in increased expression of MT2 mRNA] |
CTD |
PMID:35027733 |
|
NCBI chr19:10,837,934...10,838,708
|
|
G |
Nppb |
natriuretic peptide B |
multiple interactions |
EXP |
Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]] |
CTD |
PMID:35093381 |
|
NCBI chr 5:163,699,955...163,701,314
|
|
G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
EXP |
Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in decreased expression of OPA1 protein]] |
CTD |
PMID:35093381 |
|
NCBI chr11:84,612,943...84,690,025
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage |
ISO |
Verteporfin results in increased cleavage of PARP1 protein |
CTD |
PMID:31494105 |
|
NCBI chr13:94,839,484...94,871,295
|
|
G |
Rasal2 |
RAS protein activator like 2 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [RASAL2 protein results in increased activity of YAP1 protein] |
CTD |
PMID:34826200 |
|
NCBI chr13:69,279,882...69,569,161
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[Verteporfin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in decreased expression of RELA protein; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of and results in increased phosphorylation of RELA protein] |
CTD |
PMID:31812773 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
decreases expression multiple interactions |
ISO |
Verteporfin results in decreased expression of STAT1 protein Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of and results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:31812773 |
|
NCBI chr 9:56,911,522...56,951,926
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions decreases expression |
ISO |
Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of and results in increased phosphorylation of STAT3 protein] Verteporfin results in decreased expression of STAT3 protein |
CTD |
PMID:31812773 |
|
NCBI chr10:86,311,528...86,363,513
|
|
G |
Tead1 |
TEA domain transcription factor 1 |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [YAP1 protein binds to TEAD1 protein] |
CTD |
PMID:29893953 |
|
NCBI chr 1:166,791,900...167,010,591
|
|
G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
ISO |
[Verteporfin co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA; Verteporfin inhibits the reaction [[calcipotriene co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA] |
CTD |
PMID:38992766 |
|
NCBI chr X:3,766,509...3,772,578
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
Verteporfin inhibits the reaction [[calcipotriene co-treated with Carbon Tetrachloride] results in increased expression of TNF mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein] [EVP 4593 co-treated with Verteporfin] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; Verteporfin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA] |
CTD |
PMID:31812773 PMID:38992766 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Top2a |
DNA topoisomerase II alpha |
multiple interactions |
ISO |
[Verteporfin co-treated with calcipotriene] inhibits the reaction [Carbon Tetrachloride results in increased expression of TOP2A mRNA]; Verteporfin inhibits the reaction [[calcipotriene co-treated with Carbon Tetrachloride] results in increased expression of TOP2A mRNA]; Verteporfin inhibits the reaction [Carbon Tetrachloride results in increased expression of TOP2A mRNA] |
CTD |
PMID:38992766 |
|
NCBI chr10:84,441,954...84,473,093
|
|
G |
Yap1 |
Yes1 associated transcriptional regulator |
multiple interactions decreases expression decreases activity |
ISO EXP |
Verteporfin inhibits the reaction [AMOTL1 protein results in increased activity of YAP1 protein]; Verteporfin inhibits the reaction [RASAL2 protein results in increased activity of YAP1 protein]; Verteporfin inhibits the reaction [YAP1 protein results in increased expression of ANKRD1 mRNA]; Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN1 mRNA]; Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN2 mRNA] Verteporfin inhibits the reaction [YAP1 protein binds to TEAD1 protein] Verteporfin results in decreased expression of YAP1 protein Verteporfin results in decreased activity of YAP1 protein Verteporfin inhibits the reaction [Melatonin inhibits the reaction [Doxorubicin results in increased phosphorylation of YAP1 protein]] |
CTD |
PMID:29725256 PMID:29893953 PMID:31494105 PMID:34351699 PMID:34480788 PMID:34826200 PMID:35093381 More...
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|
NCBI chr 8:5,095,705...5,166,808
|
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