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Accession:CHEBI:32269 term browser browse the term
Definition:An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine.
Synonyms:exact_synonym: (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate
 related_synonym: 1alphaH,5alphaH-Tropan-3alpha-yl indole-3-carboxylate;   Formula=C17H20N2O2;   InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3/t11-,12+,13+;   InChIKey=ZNRGQMMCGHDTEI-ITGUQSILSA-N;   SMILES=CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c[nH]c2ccccc12;   tropisetronum
 xref: CAS:89565-68-4 "ChemIDplus";   CAS:89565-68-4 "KEGG COMPOUND";   Drug_Central:2775 "DrugCentral";   KEGG:C13666;   KEGG:D02130
 xref_mesh: MESH:C045504
 xref: PDBeChem:TKT;   PMID:22905891 "Europe PMC";   PMID:23135693 "Europe PMC";   PMID:23415734 "Europe PMC";   PMID:23440693 "Europe PMC";   PMID:23515583 "Europe PMC";   PMID:23717236 "Europe PMC";   PMID:23727438 "Europe PMC";   PMID:23774631 "Europe PMC";   PMID:23868810 "Europe PMC";   PMID:23896722 "Europe PMC";   PMID:23937291 "Europe PMC";   PMID:24226381 "Europe PMC";   PMID:24374478 "Europe PMC";   PMID:24389031 "Europe PMC";   PMID:24455480 "Europe PMC";   PMID:24461640 "Europe PMC";   Reaxys:3619989 "Reaxys";   Wikipedia:Tropisetron
 cyclic_relationship: is_conjugate_base_of CHEBI:77571

show annotations for term's descendants       view all columns           Sort by:
tropisetron term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        immunomodulator 12640
          tropisetron 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                organic heterocyclic compound 18151
                                  organic heteropolycyclic compound 17415
                                    organic heterobicyclic compound 15891
                                      benzopyrrole 5750
                                        indoles 5526
                                          indolyl carboxylic acid 3169
                                            indol-3-yl carboxylic acid 3168
                                              indole-3-carboxylic acid 12
                                                tropisetron 11
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.