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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tenoxicam
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Accession:CHEBI:32192 term browser browse the term
Definition:A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain and inflammation in osteoarthritis and rheumatoid arthritis. It is also indicated for short term treatment of acute musculoskeletal disorders including strains, sprains and other soft-tissue injuries.
Synonyms:exact_synonym: 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
 related_synonym: Formula=C13H11N3O4S2;   InChI=1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18);   InChIKey=LZNWYQJJBLGYLT-UHFFFAOYSA-N;   Mobiflex;   SMILES=CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O;   Tilcotil;   tenoxicamum
 xref: CAS:59804-37-4;   DrugBank:DB00469;   Drug_Central:2595;   KEGG:D01767
 xref_mesh: MESH:C032801
 xref: PMID:21129461;   PMID:21327813;   PMID:21682312;   PMID:21712619;   PMID:21777594;   PMID:21929527;   PMID:21981557;   PMID:22095696;   PMID:22182582;   PMID:22306394;   PMID:22675955;   PMID:22841852;   PMID:22876956;   PMID:23204620;   PMID:23273940;   PMID:23340327;   PMID:23480456;   PMID:23656309;   PMID:23932198;   PMID:24037655;   PMID:24093711;   PMID:28166217;   Patent:US2008014272;   Patent:US4687766;   Reaxys:572193;   Wikipedia:Tenoxicam


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tenoxicam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO tenoxicam inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15100168 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      application 19426
        anti-inflammatory agent 14965
          anti-inflammatory drug 13624
            non-steroidal anti-inflammatory drug 12708
              tenoxicam 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        carboacyl group 17372
                                          univalent carboacyl group 17372
                                            carbamoyl group 17158
                                              carboxamide 17158
                                                monocarboxylic acid amide 14569
                                                  tenoxicam 1
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