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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tenoxicam
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Accession:CHEBI:32192 term browser browse the term
Definition:A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain and inflammation in osteoarthritis and rheumatoid arthritis. It is also indicated for short term treatment of acute musculoskeletal disorders including strains, sprains and other soft-tissue injuries.
Synonyms:exact_synonym: 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
 related_synonym: Formula=C13H11N3O4S2;   InChI=1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18);   InChIKey=LZNWYQJJBLGYLT-UHFFFAOYSA-N;   Mobiflex;   SMILES=CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O;   Tilcotil;   tenoxicamum
 xref: CAS:59804-37-4;   DrugBank:DB00469;   Drug_Central:2595;   KEGG:D01767
 xref_mesh: MESH:C032801
 xref: PMID:21129461;   PMID:21327813;   PMID:21682312;   PMID:21712619;   PMID:21777594;   PMID:21929527;   PMID:21981557;   PMID:22095696;   PMID:22182582;   PMID:22306394;   PMID:22675955;   PMID:22841852;   PMID:22876956;   PMID:23204620;   PMID:23273940;   PMID:23340327;   PMID:23480456;   PMID:23656309;   PMID:23932198;   PMID:24037655;   PMID:24093711;   PMID:28166217;   Patent:US2008014272;   Patent:US4687766;   Reaxys:572193;   Wikipedia:Tenoxicam



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tenoxicam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO tenoxicam inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15100168 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        anti-inflammatory agent 15841
          anti-inflammatory drug 13634
            non-steroidal anti-inflammatory drug 12719
              tenoxicam 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        carboacyl group 17469
                                          univalent carboacyl group 17469
                                            carbamoyl group 17285
                                              carboxamide 17285
                                                monocarboxylic acid amide 15010
                                                  tenoxicam 1
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