Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Tegafur
go back to main search page
Accession:CHEBI:32188 term browser browse the term
Definition:A pyrimidine that has formula C8H9FN2O3.
Synonyms:related_synonym: FT-207;   Formula=C8H9FN2O3;   InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13);   InChIKey=WFWLQNSHRPWKFK-UHFFFAOYSA-N;   SMILES=Fc1cn(C2CCCO2)c(=O)[nH]c1=O;   florafur;   ftorafur;   futraful
 xref: CAS:17902-23-7;   Drug_Central:4398;   KEGG:C12673;   KEGG:D01244;   LINCS:LSM-5155
 xref_mesh: MESH:D005641


show annotations for term's descendants           Sort by:
Tegafur term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cda cytidine deaminase affects response to substance ISO CDA gene polymorphism affects the susceptibility to Tegafur CTD PMID:18537153 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects response to substance ISO DPYD gene polymorphism affects the susceptibility to Tegafur CTD PMID:18537153 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Tegafur inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Tp53 tumor protein p53 affects response to substance
multiple interactions		 ISO TP53 protein affects the susceptibility to Tegafur
TP53 protein affects the susceptibility to [Uracil co-treated with Tegafur]		 CTD PMID:15182437 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tyms thymidylate synthetase affects response to substance ISO TYMS promoter polymorphism affects the susceptibility to Tegafur CTD PMID:16617381 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    chemical entity 19930
      molecular entity 19930
        polyatomic entity 19887
          heteroatomic molecular entity 19841
            halide 18697
              organohalogen compound 18561
                Tegafur 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            organic molecule 19764
                              organic cyclic compound 19553
                                organic heterocyclic compound 18905
                                  organic heteromonocyclic compound 17827
                                    diazines 13234
                                      pyrimidines 13100
                                        Tegafur 5
paths to the root