Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tandospirone citrate
go back to main search page
Accession:CHEBI:32182 term browser browse the term
Definition:A citrate salt of tandospirone , comprising equimolar amounts of citric acid and tandospirone. It is an anxiolytic drug used in the treatment of anxiety disorders.
Synonyms:related_synonym: Formula=C21H29N5O2.C6H8O7;   InChI=1S/C21H29N5O2.C6H8O7/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21;7-3(8)1-6(13,5(11)12)2-4(9)10/h3,6-7,15-18H,1-2,4-5,8-14H2;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t15-,16+,17+,18-;;   InChIKey=DMLGUJHNIWGCKM-DPFKZJTMSA-N;   SM 3997;   SM-3997 citrate;   SMILES=[C@]12([C@@]([C@@]3(C[C@]1(CC3)[H])[H])(C(N(C2=O)CCCCN4CCN(CC4)C5=NC=CC=N5)=O)[H])[H].C(=O)(O)C(CC(=O)O)(CC(=O)O)O;   Sediel;   metanopirone citrate
 xref: CAS:112457-95-1;   KEGG:D01992
 xref_mesh: MESH:C055267
 xref: PMID:11332196;   PMID:11481861;   PMID:11889759;   PMID:12355852;   PMID:12710093;   PMID:19638966;   PMID:2566565;   PMID:29254282;   PMID:31075722;   PMID:7904073



show annotations for term's descendants           Sort by:
tandospirone citrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]; WAY 100135 inhibits the reaction [tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]] CTD PMID:19352073 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19740
    role 19713
      biological role 19711
        biochemical role 19429
          cofactor 15974
            ammonium 8300
              ammonium ion derivative 8296
                tandospirone(1+) 1
                  tandospirone citrate 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    main group molecular entity 19686
                      s-block molecular entity 19541
                        hydrogen molecular entity 19534
                          hydrides 19019
                            inorganic hydride 17950
                              pnictogen hydride 17935
                                nitrogen hydride 17832
                                  ammonium 8300
                                    ammonium ion derivative 8296
                                      tandospirone(1+) 1
                                        tandospirone citrate 1
paths to the root