CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: tamibarotene
Accession: CHEBI:32181
browse the term
Definition: A dicarboxylic acid monoamide resulting from the condensation of one of the carboxy groups of terephthalic acid with the amino group of 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine.
Synonyms: exact_synonym: 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid
related_synonym: Am-80; Amnoid; Formula=C22H25NO3; InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-16(9-10-17(18)21)23-19(24)14-5-7-15(8-6-14)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26); InChIKey=MUTNCGKQJGXKEM-UHFFFAOYSA-N; SMILES=CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(cc3)C(O)=O)ccc12; Tamibaro; retinobenzoic acid
xref: CAS:94497-51-5; DrugBank:DB04942; Drug_Central:3580; HMDB:HMDB0015605; KEGG:C12864; KEGG:D01418; LINCS:LSM-5493
xref_mesh: MESH:C061133
xref: PDBeChem:A80; PMID:16531727; PMID:17925887; PMID:19182380; PMID:19389933; PMID:19514122; PMID:22014829; PMID:22863914; PMID:23404745; PMID:25448496; Reaxys:3564473; Wikipedia:Tamibarotene
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Acan
aggrecan
affects expression
ISO
tamibarotene affects the expression of ACAN mRNA
CTD
PMID:15498508
NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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Acvrl1
activin A receptor like type 1
decreases expression
ISO
tamibarotene results in decreased expression of ACVRL1 mRNA
CTD
PMID:15498508
NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
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Ada
adenosine deaminase
increases expression
ISO
tamibarotene results in increased expression of ADA mRNA
CTD
PMID:15498508
NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
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Adgre1
adhesion G protein-coupled receptor E1
increases expression
ISO
tamibarotene results in increased expression of ADGRE1 mRNA
CTD
PMID:15498508
NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
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Adnp2
ADNP homeobox 2
affects expression
ISO
tamibarotene affects the expression of ADNP2 mRNA
CTD
PMID:15498508
NCBI chr18:73,571,870...73,597,088
Ensembl chr18:73,571,936...73,628,484
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Adora3
adenosine A3 receptor
affects expression
ISO
tamibarotene affects the expression of ADORA3 mRNA
CTD
PMID:15498508
NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
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Agps
alkylglycerone phosphate synthase
affects expression
ISO
tamibarotene affects the expression of AGPS mRNA
CTD
PMID:15498508
NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830
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Agt
angiotensinogen
multiple interactions
ISO
tamibarotene inhibits the reaction [AGT protein results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [AGT protein results in increased secretion of IL6 protein]
CTD
PMID:16484594
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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Ahnak
AHNAK nucleoprotein
decreases expression
ISO
tamibarotene results in decreased expression of AHNAK mRNA
CTD
PMID:15498508
NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
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Aif1
allograft inflammatory factor 1
increases expression
ISO
tamibarotene results in increased expression of AIF1 mRNA
CTD
PMID:15498508
NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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Ak4
adenylate kinase 4
decreases expression
ISO
tamibarotene results in decreased expression of AK4 mRNA
CTD
PMID:15498508
NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
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Akap9
A-kinase anchoring protein 9
decreases expression
ISO
tamibarotene results in decreased expression of AKAP9 mRNA
CTD
PMID:15498508
NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
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Alas1
5'-aminolevulinate synthase 1
increases expression
ISO
tamibarotene results in increased expression of ALAS1 mRNA
CTD
PMID:15498508
NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
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Aldh1b1
aldehyde dehydrogenase 1 family, member B1
affects expression
ISO
tamibarotene affects the expression of ALDH1B1 mRNA
CTD
PMID:15498508
NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
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Alms1
ALMS1, centrosome and basal body associated protein
decreases expression
ISO
tamibarotene results in decreased expression of ALMS1 mRNA
CTD
PMID:15498508
NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005
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Alox5ap
arachidonate 5-lipoxygenase activating protein
increases expression
ISO
tamibarotene results in increased expression of ALOX5AP mRNA
CTD
PMID:15498508
NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
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Amd1
adenosylmethionine decarboxylase 1
decreases expression
ISO
tamibarotene results in decreased expression of AMD1 mRNA
CTD
PMID:15498508
NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
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Ankrd17
ankyrin repeat domain 17
decreases expression
ISO
tamibarotene results in decreased expression of ANKRD17 mRNA
CTD
PMID:15498508
NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617
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Anxa2
annexin A2
decreases expression
ISO
tamibarotene results in decreased expression of ANXA2 mRNA
CTD
PMID:15498508
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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Ap1s2
adaptor related protein complex 1 subunit sigma 2
increases expression
ISO
tamibarotene results in increased expression of AP1S2 mRNA
CTD
PMID:15498508
NCBI chr X:30,572,746...30,598,961
Ensembl chr X:30,572,751...30,597,262
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Apbb3
amyloid beta precursor protein binding family B member 3
affects expression
ISO
tamibarotene affects the expression of APBB3 mRNA
CTD
PMID:15498508
NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
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Apc
APC regulator of WNT signaling pathway
decreases expression
ISO
tamibarotene results in decreased expression of APC mRNA
CTD
PMID:15498508
NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
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Aqp7
aquaporin 7
affects expression
ISO
tamibarotene affects the expression of AQP7 mRNA
CTD
PMID:15498508
NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
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Arf6
ARF GTPase 6
affects expression
ISO
tamibarotene affects the expression of ARF6 mRNA
CTD
PMID:15498508
NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
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Arhgap4
Rho GTPase activating protein 4
increases expression
ISO
tamibarotene results in increased expression of ARHGAP4 mRNA
CTD
PMID:15498508
NCBI chr X:151,636,071...151,651,528
Ensembl chr X:151,632,454...151,651,128
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Arhgap45
Rho GTPase activating protein 45
increases expression
ISO
tamibarotene results in increased expression of ARHGAP45 mRNA
CTD
PMID:15498508
NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268
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Arhgap8
Rho GTPase activating protein 8
increases expression
ISO
tamibarotene results in increased expression of ARHGAP8 mRNA
CTD
PMID:17229644
NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093
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Arl4c
ARF like GTPase 4C
decreases expression
ISO
tamibarotene results in decreased expression of ARL4C mRNA
CTD
PMID:15498508
NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
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Asb2
ankyrin repeat and SOCS box-containing 2
increases expression
ISO
tamibarotene results in increased expression of ASB2 mRNA
CTD
PMID:17229644
NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854
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Atp13a3
ATPase 13A3
affects expression
ISO
tamibarotene affects the expression of ATP13A3 mRNA
CTD
PMID:15498508
NCBI chr11:70,364,998...70,442,005
Ensembl chr11:70,365,322...70,441,235
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Atp1a3
ATPase Na+/K+ transporting subunit alpha 3
affects expression
ISO
tamibarotene affects the expression of ATP1A3 mRNA
CTD
PMID:15498508
NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
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Atp2b1
ATPase plasma membrane Ca2+ transporting 1
affects expression
ISO
tamibarotene affects the expression of ATP2B1 mRNA
CTD
PMID:15498508
NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
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Atp6v0a1
ATPase H+ transporting V0 subunit a1
increases expression
ISO
tamibarotene results in increased expression of ATP6V0A1 mRNA
CTD
PMID:15498508
NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
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Atp6v0a2
ATPase H+ transporting V0 subunit a2
decreases expression
ISO
tamibarotene results in decreased expression of ATP6V0A2 mRNA
CTD
PMID:15498508
NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069
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Atp6v1a
ATPase H+ transporting V1 subunit A
affects expression
ISO
tamibarotene affects the expression of ATP6V1A mRNA
CTD
PMID:15498508
NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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Atpaf2
ATP synthase mitochondrial F1 complex assembly factor 2
affects expression
ISO
tamibarotene affects the expression of ATPAF2 mRNA
CTD
PMID:15498508
NCBI chr10:45,205,658...45,221,891
Ensembl chr10:45,197,441...45,221,026
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Atrx
ATRX, chromatin remodeler
decreases expression
ISO
tamibarotene results in decreased expression of ATRX mRNA
CTD
PMID:15498508
NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330
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Atxn7l3b
ataxin 7-like 3B
affects expression
ISO
tamibarotene affects the expression of ATXN7L3B mRNA
CTD
PMID:15498508
NCBI chr 7:48,322,451...48,325,975
Ensembl chr 7:48,321,755...48,328,878
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Axin1
axin 1
increases expression
ISO
tamibarotene results in increased expression of AXIN1 mRNA
CTD
PMID:15498508
NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615
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Azin1
antizyme inhibitor 1
affects expression
ISO
tamibarotene affects the expression of AZIN1 mRNA
CTD
PMID:15498508
NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
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Bak1
BCL2-antagonist/killer 1
increases expression
ISO
tamibarotene results in increased expression of BAK1 mRNA
CTD
PMID:15498508
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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Bcat1
branched chain amino acid transaminase 1
affects expression
ISO
tamibarotene affects the expression of BCAT1 mRNA
CTD
PMID:15498508
NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
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Bcl11a
BCL11 transcription factor A
decreases expression
ISO
tamibarotene results in decreased expression of BCL11A mRNA
CTD
PMID:15498508
NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
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Bcl2
BCL2, apoptosis regulator
multiple interactions affects expression decreases expression
ISO
Triiodothyronine promotes the reaction [tamibarotene results in decreased expression of BCL2 mRNA] tamibarotene affects the expression of BCL2 mRNA
CTD
PMID:11201846 PMID:15498508
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2a1
BCL2-related protein A1
increases expression multiple interactions
ISO
tamibarotene results in increased expression of BCL2A1 mRNA; tamibarotene results in increased expression of BCL2A1A mRNA Triiodothyronine promotes the reaction [tamibarotene results in increased expression of BCL2A1A mRNA]
CTD
PMID:11201846 PMID:15498508
NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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Bcl7a
BAF chromatin remodeling complex subunit BCL7A
decreases expression
ISO
tamibarotene results in decreased expression of BCL7A mRNA
CTD
PMID:15498508
NCBI chr12:33,211,978...33,243,903
Ensembl chr12:33,223,931...33,243,886
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Bclaf1
BCL2-associated transcription factor 1
decreases expression
ISO
tamibarotene results in decreased expression of BCLAF1 mRNA
CTD
PMID:15498508
NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
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Bdnf
brain-derived neurotrophic factor
multiple interactions increases expression
ISO EXP
[tamibarotene co-treated with BDNF] results in increased expression of NTRK2 tamibarotene results in increased expression of BDNF mRNA BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK1 protein]; BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK3 protein]; BDNF affects the reaction [tamibarotene results in increased phosphorylation of NTRK2 protein]
CTD
PMID:19182380 PMID:19457078
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Bhlhe40
basic helix-loop-helix family, member e40
affects expression
ISO
tamibarotene affects the expression of BHLHE40 mRNA
CTD
PMID:15498508
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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Blmh
bleomycin hydrolase
decreases expression
ISO
tamibarotene results in decreased expression of BLMH mRNA
CTD
PMID:15498508
NCBI chr10:61,772,112...61,815,212
Ensembl chr10:61,758,478...61,815,212
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Bltp1
bridge-like lipid transfer protein family member 1
affects expression
ISO
tamibarotene affects the expression of BLTP1 mRNA
CTD
PMID:15498508
NCBI chr 2:119,708,114...119,924,697
Ensembl chr 2:119,708,209...119,924,695
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Bpi
bactericidal/permeability-increasing protein
increases expression
ISO
tamibarotene results in increased expression of BPI mRNA
CTD
PMID:15498508
NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221
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Bptf
bromodomain PHD finger transcription factor
affects expression
ISO
tamibarotene affects the expression of BPTF mRNA
CTD
PMID:15498508
NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769
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Brca1
BRCA1, DNA repair associated
decreases expression
ISO
tamibarotene results in decreased expression of BRCA1 mRNA
CTD
PMID:15498508
NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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Brca2
BRCA2, DNA repair associated
affects expression decreases expression
ISO
tamibarotene affects the expression of BRCA2 mRNA tamibarotene results in decreased expression of BRCA2 mRNA
CTD
PMID:15498508
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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Brd3
bromodomain containing 3
affects expression
ISO
tamibarotene affects the expression of BRD3 mRNA
CTD
PMID:15498508
NCBI chr 3:10,773,163...10,829,675
Ensembl chr 3:10,775,272...10,829,577
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Bst2
bone marrow stromal cell antigen 2
affects expression
ISO
tamibarotene affects the expression of BST2 mRNA
CTD
PMID:15498508
NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
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Btf3
basic transcription factor 3
affects expression
ISO
tamibarotene affects the expression of BTF3 mRNA
CTD
PMID:15498508
NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879 Ensembl chr13:29,659,231...29,666,879
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Btg2
BTG anti-proliferation factor 2
increases expression
ISO
tamibarotene results in increased expression of BTG2 mRNA
CTD
PMID:15498508
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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Cadm1
cell adhesion molecule 1
increases expression
ISO
tamibarotene results in increased expression of CADM1 mRNA
CTD
PMID:15498508
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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Camk1
calcium/calmodulin-dependent protein kinase I
increases expression
ISO
tamibarotene results in increased expression of CAMK1 mRNA
CTD
PMID:15498508
NCBI chr 4:146,481,196...146,492,039
Ensembl chr 4:146,481,196...146,492,081
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Camta2
calmodulin binding transcription activator 2
increases expression
ISO
tamibarotene results in increased expression of CAMTA2 mRNA
CTD
PMID:15498508
NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558
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Capg
capping actin protein, gelsolin like
increases expression
ISO
tamibarotene results in increased expression of CAPG mRNA
CTD
PMID:15498508
NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
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Caprin1
cell cycle associated protein 1
decreases expression
ISO
tamibarotene results in decreased expression of CAPRIN1 mRNA
CTD
PMID:15498508
NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
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Casp9
caspase 9
increases expression
ISO
tamibarotene results in increased expression of CASP9 mRNA
CTD
PMID:15498508
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cbx3
chromobox 3
affects expression
ISO
tamibarotene affects the expression of CBX3 mRNA
CTD
PMID:15498508
NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283 Ensembl chr 4:80,546,010...80,559,283
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Ccdc22
coiled-coil domain containing 22
affects expression
ISO
tamibarotene affects the expression of CCDC22 mRNA
CTD
PMID:15498508
NCBI chr X:14,898,296...14,910,244
Ensembl chr X:14,898,296...14,910,244
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Ccdc93
coiled-coil domain containing 93
decreases expression
ISO
tamibarotene results in decreased expression of CCDC93 mRNA
CTD
PMID:15498508
NCBI chr13:32,607,618...32,675,993
Ensembl chr13:32,607,587...32,676,023
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Ccl4
C-C motif chemokine ligand 4
increases expression
ISO
tamibarotene results in increased expression of CCL4 mRNA
CTD
PMID:15498508
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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Ccl5
C-C motif chemokine ligand 5
increases expression decreases expression
ISO
tamibarotene results in increased expression of CCL5 mRNA tamibarotene results in decreased expression of CCL5 mRNA
CTD
PMID:15498508 PMID:20861477
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccl9
C-C motif chemokine ligand 9
decreases expression
ISO
tamibarotene results in decreased expression of CCL6 mRNA
CTD
PMID:20861477
NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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Ccnd1
cyclin D1
increases expression
ISO
tamibarotene results in increased expression of CCND1 mRNA
CTD
PMID:15498508
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccnf
cyclin F
decreases expression
ISO
tamibarotene results in decreased expression of CCNF mRNA
CTD
PMID:15498508
NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
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Ccng1
cyclin G1
affects expression
ISO
tamibarotene affects the expression of CCNG1 mRNA
CTD
PMID:15498508
NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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Ccr1
C-C motif chemokine receptor 1
increases expression
ISO
tamibarotene results in increased expression of CCR1 mRNA
CTD
PMID:15498508
NCBI chr 8:123,556,286...123,561,841
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Cd22
CD22 molecule
affects expression
ISO
tamibarotene affects the expression of CD22 mRNA
CTD
PMID:15498508
NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322
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Cd300a
Cd300a molecule
increases expression
ISO
tamibarotene results in increased expression of CD300A mRNA
CTD
PMID:15498508
NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
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Cd300c
CD300c molecule
increases expression
ISO
tamibarotene results in increased expression of CD300C mRNA
CTD
PMID:15498508
NCBI chr10:100,228,254...100,233,207
Ensembl chr10:100,228,430...100,232,879
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Cd36
CD36 molecule
multiple interactions
ISO
tamibarotene promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA] tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]
CTD
PMID:16484594
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cd38
CD38 molecule
increases expression
ISO
tamibarotene results in increased expression of CD38 mRNA; tamibarotene results in increased expression of CD38 protein
CTD
PMID:15498508 PMID:21393419
NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
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Cd3d
CD3 delta subunit of T-cell receptor complex
decreases expression
ISO
tamibarotene results in decreased expression of CD3D mRNA
CTD
PMID:20861477
NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809
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Cd3g
CD3 gamma subunit of T-cell receptor complex
decreases expression
ISO
tamibarotene results in decreased expression of CD3G mRNA
CTD
PMID:20861477
NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147
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Cd44
CD44 molecule
decreases expression affects expression
ISO
tamibarotene results in decreased expression of CD44 mRNA tamibarotene affects the expression of CD44 mRNA
CTD
PMID:15498508 PMID:17229644
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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Cd53
Cd53 molecule
increases expression
ISO
tamibarotene results in increased expression of CD53 mRNA
CTD
PMID:15498508
NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657
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Cd68
Cd68 molecule
decreases expression
ISO
tamibarotene results in decreased expression of CD68 mRNA
CTD
PMID:20861477
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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Cd69
Cd69 molecule
affects expression
ISO
tamibarotene affects the expression of CD69 mRNA
CTD
PMID:15498508
NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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Cd74
CD74 molecule
increases expression
ISO
tamibarotene results in increased expression of CD74 mRNA
CTD
PMID:17229644
NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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Cd79a
CD79a molecule
increases expression
ISO
tamibarotene results in increased expression of CD79A mRNA
CTD
PMID:17229644
NCBI chr 1:80,493,581...80,497,936
Ensembl chr 1:80,493,581...80,497,935
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Cdc25a
cell division cycle 25A
decreases expression
ISO
tamibarotene results in decreased expression of CDC25A mRNA
CTD
PMID:15498508
NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
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Cdc6
cell division cycle 6
decreases expression
ISO
tamibarotene results in decreased expression of CDC6 mRNA
CTD
PMID:15498508
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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Cdk10
cyclin-dependent kinase 10
affects expression
ISO
tamibarotene affects the expression of CDK10 mRNA
CTD
PMID:15498508
NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078
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Cdk8
cyclin-dependent kinase 8
affects expression
ISO
tamibarotene affects the expression of CDK8 mRNA
CTD
PMID:15498508
NCBI chr12:8,737,198...8,805,026
Ensembl chr12:8,737,262...8,804,177
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
tamibarotene results in increased expression of CDKN1A mRNA
CTD
PMID:17229644
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Ceacam6
CEA cell adhesion molecule 6
increases expression multiple interactions
ISO
tamibarotene results in increased expression of CEACAM6 mRNA CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEACAM6 mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEACAM6 mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEACAM6 mRNA]
CTD
PMID:27737899
NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:80,416,531...80,434,668
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Cebpb
CCAAT/enhancer binding protein beta
increases expression
ISO
tamibarotene results in increased expression of CEBPB mRNA
CTD
PMID:15498508
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Cebpd
CCAAT/enhancer binding protein delta
increases expression
ISO
tamibarotene results in increased expression of CEBPD mRNA
CTD
PMID:15498508
NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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Cebpe
CCAAT/enhancer binding protein epsilon
increases expression multiple interactions
ISO
tamibarotene results in increased expression of CEBPE mRNA CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEBPE mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEBPE mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEBPE mRNA]
CTD
PMID:27737899
NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814
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Cebpg
CCAAT/enhancer binding protein gamma
decreases expression
ISO
tamibarotene results in decreased expression of CEBPG mRNA
CTD
PMID:15498508
NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
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Celf1
CUGBP, Elav-like family member 1
affects expression
ISO
tamibarotene affects the expression of CELF1 mRNA
CTD
PMID:15498508
NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426
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Cep135
centrosomal protein 135
decreases expression
ISO
tamibarotene results in decreased expression of CEP135 mRNA
CTD
PMID:15498508
NCBI chr14:31,530,538...31,595,812
Ensembl chr14:31,531,482...31,595,772
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Chka
choline kinase alpha
decreases expression
ISO
tamibarotene results in decreased expression of CHKA mRNA
CTD
PMID:15498508
NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
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Ciita
class II, major histocompatibility complex, transactivator
increases expression
ISO
tamibarotene results in increased expression of CIITA mRNA
CTD
PMID:17229644
NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
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Clcnka
chloride voltage-gated channel Ka
decreases expression
ISO
tamibarotene results in decreased expression of CLCNKA mRNA
CTD
PMID:15498508
NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
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Cltb
clathrin, light chain B
increases expression
ISO
tamibarotene results in increased expression of CLTB mRNA
CTD
PMID:15498508
NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
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Col11a2
collagen type XI alpha 2 chain
affects expression
ISO
tamibarotene affects the expression of COL11A2 mRNA
CTD
PMID:15498508
NCBI chr20:4,786,932...4,816,598
Ensembl chr20:4,786,929...4,815,985
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Coro1a
coronin 1A
increases expression
ISO
tamibarotene results in increased expression of CORO1A mRNA
CTD
PMID:15498508
NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
G
Creb1
cAMP responsive element binding protein 1
affects expression
ISO
tamibarotene affects the expression of CREB1 mRNA
CTD
PMID:15498508
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
G
Creb3
cAMP responsive element binding protein 3
increases expression
ISO
tamibarotene results in increased expression of CREB3 mRNA
CTD
PMID:15498508
NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390
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Creg1
cellular repressor of E1A-stimulated genes 1
increases expression
ISO
tamibarotene results in increased expression of CREG1 mRNA
CTD
PMID:15498508
NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
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Csf3
colony stimulating factor 3
multiple interactions
ISO
[tamibarotene co-treated with CSF3 protein] results in increased expression of CEACAM8 mRNA; CSF3 protein inhibits the reaction [tamibarotene results in decreased expression of ITGB2 mRNA]; CSF3 protein inhibits the reaction [tamibarotene results in increased expression of ITGAM mRNA]; CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEACAM6 mRNA]; CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEBPE mRNA]; CSF3 protein promotes the reaction [tamibarotene results in increased expression of RARB mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEACAM6 mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEBPE mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in increased expression of ITGB2 mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEACAM6 mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEBPE mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of RARB mRNA]
CTD
PMID:27737899
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Csrp1
cysteine and glycine-rich protein 1
affects expression
ISO
tamibarotene affects the expression of CSRP1 mRNA
CTD
PMID:15498508
NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
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Cst3
cystatin C
increases expression
ISO
tamibarotene results in increased expression of CST3 mRNA
CTD
PMID:15498508
NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
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Ctif
cap binding complex dependent translation initiation factor
decreases expression
ISO
tamibarotene results in decreased expression of CTIF mRNA
CTD
PMID:15498508
NCBI chr18:69,056,151...69,327,454
Ensembl chr18:69,059,519...69,327,385
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Ctnnal1
catenin alpha-like 1
decreases expression
ISO
tamibarotene results in decreased expression of CTNNAL1 mRNA
CTD
PMID:15498508
NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431
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Ctsa
cathepsin A
increases expression
ISO
tamibarotene results in increased expression of CTSA mRNA
CTD
PMID:17229644
NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
G
Ctsd
cathepsin D
increases expression
ISO
tamibarotene results in increased expression of CTSD mRNA
CTD
PMID:15498508
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
G
Cul1
cullin 1
decreases expression
ISO
tamibarotene results in decreased expression of CUL1 mRNA
CTD
PMID:15498508
NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
G
Cxcl10
C-X-C motif chemokine ligand 10
decreases expression
ISO
tamibarotene results in decreased expression of CXCL10 mRNA
CTD
PMID:20861477
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl9
C-X-C motif chemokine ligand 9
decreases expression
ISO
tamibarotene results in decreased expression of CXCL9 mRNA
CTD
PMID:20861477
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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Cxcr4
C-X-C motif chemokine receptor 4
multiple interactions decreases expression
ISO
tamibarotene results in increased uptake of and affects the localization of CXCR4 protein tamibarotene results in decreased expression of CXCR4 mRNA
CTD
PMID:20141446 PMID:20861477
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
G
Cxcr5
C-X-C motif chemokine receptor 5
increases expression
ISO
tamibarotene results in increased expression of CXCR5 mRNA
CTD
PMID:15498508
NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893
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Cyba
cytochrome b-245 alpha chain
increases expression
ISO
tamibarotene results in increased expression of CYBA mRNA
CTD
PMID:15498508
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
G
Cybb
cytochrome b-245 beta chain
increases expression
ISO
tamibarotene results in increased expression of CYBB mRNA
CTD
PMID:15498508
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
multiple interactions
ISO
tamibarotene inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]
CTD
PMID:16289102
NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
G
Daam1
dishevelled associated activator of morphogenesis 1
decreases expression
ISO
tamibarotene results in decreased expression of DAAM1 mRNA
CTD
PMID:15498508
NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114
G
Dagla
diacylglycerol lipase, alpha
affects expression
ISO
tamibarotene affects the expression of DAGLA mRNA
CTD
PMID:15498508
NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
G
Dapk2
death-associated protein kinase 2
increases expression
ISO
tamibarotene results in increased expression of DAPK2 mRNA
CTD
PMID:15498508
NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
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Ddx18
DEAD-box helicase 18
affects expression
ISO
tamibarotene affects the expression of DDX18 mRNA
CTD
PMID:15498508
NCBI chr13:32,729,697...32,743,161
Ensembl chr13:32,729,700...32,743,161
G
Ddx21
DExD-box helicase 21
decreases expression
ISO
tamibarotene results in decreased expression of DDX21 mRNA
CTD
PMID:15498508
NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
G
Ddx51
DEAD-box helicase 51
affects expression
ISO
tamibarotene affects the expression of DDX51 mRNA
CTD
PMID:15498508
NCBI chr12:46,011,303...46,015,989
Ensembl chr12:46,011,070...46,016,200
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Dhrs3
dehydrogenase/reductase 3
increases expression
ISO
tamibarotene results in increased expression of DHRS3 mRNA
CTD
PMID:15498508
NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
G
Dmbt1
deleted in malignant brain tumors 1
affects expression
ISO
tamibarotene affects the expression of DMBT1 mRNA
CTD
PMID:15498508
NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
G
Dok2
docking protein 2
increases expression
ISO
tamibarotene results in increased expression of DOK2 mRNA
CTD
PMID:15498508
NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402
G
Dph1
diphthamide biosynthesis 1
increases expression
ISO
tamibarotene results in increased expression of DPH1 mRNA
CTD
PMID:15498508
NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850
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Dst
dystonin
decreases expression
ISO
tamibarotene results in decreased expression of DST mRNA
CTD
PMID:15498508
NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
G
Dusp10
dual specificity phosphatase 10
decreases expression
ISO
tamibarotene results in decreased expression of DUSP10 mRNA
CTD
PMID:17229644
NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
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Dvl1
dishevelled segment polarity protein 1
decreases expression
ISO
tamibarotene results in decreased expression of DVL1 mRNA
CTD
PMID:15498508
NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664
G
Dync1li2
dynein, cytoplasmic 1 light intermediate chain 2
decreases expression
ISO
tamibarotene results in decreased expression of DYNC1LI2 mRNA
CTD
PMID:15498508
NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
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Eci1
enoyl-CoA delta isomerase 1
affects expression
ISO
tamibarotene affects the expression of ECI1 mRNA
CTD
PMID:15498508
NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
G
Edn1
endothelin 1
increases expression
ISO
tamibarotene results in increased expression of EDN1 mRNA
CTD
PMID:15498508
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
G
Edn2
endothelin 2
increases expression
ISO
tamibarotene results in increased expression of EDN2 mRNA
CTD
PMID:15498508
NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
G
Edrf1
erythroid differentiation regulatory factor 1
decreases expression
ISO
tamibarotene results in decreased expression of EDRF1 mRNA
CTD
PMID:15498508
NCBI chr 1:188,441,514...188,478,743
Ensembl chr 1:188,441,634...188,478,701
G
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
increases expression
ISO
tamibarotene results in increased expression of EEF1A1 mRNA
CTD
PMID:15498508
NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
G
Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
decreases expression
ISO
tamibarotene results in decreased expression of EEF1E1 mRNA
CTD
PMID:15498508
NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720
G
Egr3
early growth response 3
increases expression
ISO
tamibarotene results in increased expression of EGR3 mRNA
CTD
PMID:15498508
NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
G
Eif2a
eukaryotic translation initiation factor 2A
affects expression
ISO
tamibarotene affects the expression of EIF2A mRNA
CTD
PMID:15498508
NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
G
Eif2s3
eukaryotic translation initiation factor 2 subunit gamma
affects expression
ISO
tamibarotene affects the expression of EIF2S3 mRNA
CTD
PMID:15498508
NCBI chr X:58,916,513...58,939,923
Ensembl chr X:58,917,490...58,940,686
G
Eif3a
eukaryotic translation initiation factor 3, subunit A
decreases expression
ISO
tamibarotene results in decreased expression of EIF3A mRNA
CTD
PMID:15498508
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
G
Eif4a2
eukaryotic translation initiation factor 4A2
decreases expression
ISO
tamibarotene results in decreased expression of EIF4A2 mRNA
CTD
PMID:15498508
NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
G
Eif4b
eukaryotic translation initiation factor 4B
decreases expression
ISO
tamibarotene results in decreased expression of EIF4B mRNA
CTD
PMID:15498508
NCBI chr 7:133,206,637...133,228,436
G
Epx
eosinophil peroxidase
decreases expression
ISO
tamibarotene results in decreased expression of EPX mRNA
CTD
PMID:15498508
NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
G
Ercc8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit
decreases expression
ISO
tamibarotene results in decreased expression of ERCC8 mRNA
CTD
PMID:15498508
NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859
G
Esr1
estrogen receptor 1
increases activity
ISO
tamibarotene results in increased activity of ESR1 protein
CTD
PMID:25257666
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Evx1
even-skipped homeobox 1
decreases expression
ISO
tamibarotene results in decreased expression of EVX1 mRNA
CTD
PMID:15498508
NCBI chr 4:81,416,590...81,420,967
Ensembl chr 4:81,416,590...81,420,967
G
Exoc3
exocyst complex component 3
affects expression
ISO
tamibarotene affects the expression of EXOC3 mRNA
CTD
PMID:15498508
NCBI chr 1:29,091,298...29,122,056
Ensembl chr 1:29,091,294...29,122,045
G
F3
coagulation factor III, tissue factor
multiple interactions decreases expression
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in decreased expression of F3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in decreased expression of F3 mRNA]
CTD
PMID:15020266
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
G
Fam89b
family with sequence similarity 89, member B
increases expression
ISO
tamibarotene results in increased expression of FAM89B mRNA
CTD
PMID:15498508
NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367
G
Fas
Fas cell surface death receptor
increases activity
ISO
tamibarotene results in increased activity of FAS protein
CTD
PMID:15703382
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
G
Fat1
FAT atypical cadherin 1
affects expression
ISO
tamibarotene affects the expression of FAT1 mRNA
CTD
PMID:15498508
NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107
G
Fbn2
fibrillin 2
decreases expression
ISO
tamibarotene results in decreased expression of FBN2 mRNA
CTD
PMID:15498508
NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976
G
Fbp1
fructose-bisphosphatase 1
increases expression
ISO
tamibarotene results in increased expression of FBP1 mRNA
CTD
PMID:15498508
NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
G
Fcer1g
Fc epsilon receptor Ig
increases expression
ISO
tamibarotene results in increased expression of FCER1G mRNA
CTD
PMID:15498508
NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443
G
Fcgr1a
Fc gamma receptor 1A
affects expression
ISO
tamibarotene affects the expression of FCGR1A mRNA
CTD
PMID:15498508
NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
G
Fcgr2b
Fc gamma receptor 2B
affects expression
ISO
tamibarotene affects the expression of FCGR2B mRNA
CTD
PMID:15498508
NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
G
Fes
FES proto-oncogene, tyrosine kinase
affects expression
ISO
tamibarotene affects the expression of FES mRNA
CTD
PMID:15498508
NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934
G
Fgfr1
Fibroblast growth factor receptor 1
decreases expression
ISO
tamibarotene results in decreased expression of FGFR1 mRNA
CTD
PMID:15498508
NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
G
Fgr
FGR proto-oncogene, Src family tyrosine kinase
increases expression
ISO
tamibarotene results in increased expression of FGR mRNA
CTD
PMID:15498508
NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
G
Fkbp5
FKBP prolyl isomerase 5
decreases expression
ISO
tamibarotene results in decreased expression of FKBP5 mRNA
CTD
PMID:15498508
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
G
Flot1
flotillin 1
increases expression
ISO
tamibarotene results in increased expression of FLOT1 mRNA
CTD
PMID:15498508
NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
G
Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
tamibarotene results in increased expression of FOSB mRNA
CTD
PMID:15498508
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
G
Foxo4
forkhead box O4
increases expression
ISO
tamibarotene results in increased expression of FOXO4 mRNA
CTD
PMID:15498508
NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115
G
Foxp3
forkhead box P3
decreases expression
ISO
tamibarotene results in decreased expression of FOXP3 mRNA
CTD
PMID:22077062
NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
G
Fuca1
alpha-L-fucosidase 1
increases expression
ISO
tamibarotene results in increased expression of FUCA1 mRNA
CTD
PMID:15498508
NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972
G
Fut4
fucosyltransferase 4
increases expression
ISO
tamibarotene results in increased expression of FUT4 mRNA
CTD
PMID:15498508
NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
G
Fyb1
FYN binding protein 1
affects expression
ISO
tamibarotene affects the expression of FYB1 mRNA
CTD
PMID:15498508
NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
G
Fyn
FYN proto-oncogene, Src family tyrosine kinase
decreases expression
ISO
tamibarotene results in decreased expression of FYN mRNA
CTD
PMID:15498508
NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
decreases expression
ISO
tamibarotene results in decreased expression of GADD45A mRNA
CTD
PMID:15498508
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Galk2
galactokinase 2
decreases expression
ISO
tamibarotene results in decreased expression of GALK2 mRNA
CTD
PMID:15498508
NCBI chr 3:113,110,057...113,243,014
Ensembl chr 3:113,110,030...113,233,306
G
Galt
galactose-1-phosphate uridylyltransferase
increases expression
ISO
tamibarotene results in increased expression of GALT mRNA
CTD
PMID:15498508
NCBI chr 5:56,927,039...56,930,284
Ensembl chr 5:56,926,724...56,930,265
G
Gata2
GATA binding protein 2
decreases expression
ISO
tamibarotene results in decreased expression of GATA2 mRNA
CTD
PMID:15498508
NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
G
Gatad1
GATA zinc finger domain containing 1
decreases expression
ISO
tamibarotene results in decreased expression of GATAD1 mRNA
CTD
PMID:15498508
NCBI chr 4:30,507,530...30,519,107
Ensembl chr 4:30,507,538...30,519,107
G
Gatc
glutamyl-tRNA amidotransferase subunit C
affects expression
ISO
tamibarotene affects the expression of GATC mRNA
CTD
PMID:15498508
NCBI chr12:41,270,096...41,278,067
Ensembl chr12:41,270,087...41,277,995
G
Gca
grancalcin
increases expression
ISO
tamibarotene results in increased expression of GCA mRNA
CTD
PMID:15498508
NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581
G
Gfap
glial fibrillary acidic protein
increases expression
EXP
tamibarotene results in increased expression of GFAP
CTD
PMID:19182380
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
G
Gfpt1
glutamine fructose-6-phosphate transaminase 1
affects expression
ISO
tamibarotene affects the expression of GFPT1 mRNA
CTD
PMID:15498508
NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
G
Ggt1
gamma-glutamyltransferase 1
increases expression
ISO
tamibarotene results in increased expression of GGT1 mRNA
CTD
PMID:15498508
NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
G
Glod4
glyoxalase domain containing 4
affects expression
ISO
tamibarotene affects the expression of GLOD4 mRNA
CTD
PMID:15498508
NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898
G
Glrx
glutaredoxin
increases expression
ISO
tamibarotene results in increased expression of GLRX mRNA
CTD
PMID:15498508
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
G
Gnaq
G protein subunit alpha q
affects expression
ISO
tamibarotene affects the expression of GNAQ mRNA
CTD
PMID:15498508
NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
G
Gng4
G protein subunit gamma 4
decreases expression
ISO
tamibarotene results in decreased expression of GNG4 mRNA
CTD
PMID:15498508
NCBI chr17:86,448,708...86,497,560
Ensembl chr17:86,449,022...86,495,254
G
Gpx1
glutathione peroxidase 1
affects expression
ISO
tamibarotene affects the expression of GPX1 mRNA
CTD
PMID:15498508
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Grina
glutamate ionotropic receptor NMDA type subunit associated protein 1
increases expression affects expression
ISO
tamibarotene results in increased expression of GRINA mRNA tamibarotene affects the expression of GRINA mRNA
CTD
PMID:15498508 PMID:17229644
NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
G
Grn
granulin precursor
increases expression
ISO
tamibarotene results in increased expression of GRN mRNA
CTD
PMID:15498508
NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
G
Gsk3b
glycogen synthase kinase 3 beta
affects expression
ISO
tamibarotene affects the expression of GSK3B mRNA
CTD
PMID:15498508
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Gsn
gelsolin
increases expression
ISO
tamibarotene results in increased expression of GSN mRNA
CTD
PMID:15498508
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
G
Gstm1
glutathione S-transferase mu 1
increases expression
ISO
tamibarotene results in increased expression of GSTM1 mRNA
CTD
PMID:15498508
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Gsto1
glutathione S-transferase omega 1
increases expression
ISO
tamibarotene results in increased expression of GSTO1 mRNA
CTD
PMID:15498508
NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
G
H2ac18
H2A clustered histone 18
increases expression
ISO
tamibarotene results in increased expression of H2AC18 mRNA
CTD
PMID:15498508
NCBI chr 2:183,808,398...183,808,992
G
H4f3
H1.3 linker histone, cluster member
affects expression
ISO
tamibarotene affects the expression of H1-3 mRNA
CTD
PMID:15498508
NCBI chr17:41,551,524...41,552,303
Ensembl chr17:41,529,667...41,552,334
G
Hck
HCK proto-oncogene, Src family tyrosine kinase
increases expression
ISO
tamibarotene results in increased expression of HCK mRNA
CTD
PMID:15498508
NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
G
Hipk1
homeodomain interacting protein kinase 1
decreases expression
ISO
tamibarotene results in decreased expression of HIPK1 mRNA
CTD
PMID:15498508
NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902
G
Hira
histone cell cycle regulator
affects expression
ISO
tamibarotene affects the expression of HIRA mRNA
CTD
PMID:15498508
NCBI chr11:82,024,469...82,133,212
Ensembl chr11:82,024,469...82,133,529
G
Hk3
hexokinase 3
increases expression
ISO
tamibarotene results in increased expression of HK3 mRNA
CTD
PMID:15498508
NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863
G
Hlx
H2.0-like homeobox
affects expression
ISO
tamibarotene affects the expression of HLX mRNA
CTD
PMID:15498508
NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750
G
Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
affects expression
ISO
tamibarotene affects the expression of HMGCS1 mRNA
CTD
PMID:15498508
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
G
Hpd
4-hydroxyphenylpyruvate dioxygenase
increases expression
ISO
tamibarotene results in increased expression of HPD mRNA
CTD
PMID:15498508
NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766
G
Hpgd
15-hydroxyprostaglandin dehydrogenase
affects expression
ISO
tamibarotene affects the expression of HPGD mRNA
CTD
PMID:15498508
NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
G
Hsp90ab1
heat shock protein 90 alpha family class B member 1
affects expression
ISO
tamibarotene affects the expression of HSP90AB1 mRNA
CTD
PMID:15498508
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
G
Hsp90b1
heat shock protein 90 beta family member 1
decreases expression
ISO
tamibarotene results in decreased expression of HSP90B1 mRNA
CTD
PMID:15498508
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
G
Ice1
interactor of little elongation complex ELL subunit 1
affects expression
ISO
tamibarotene affects the expression of ICE1 mRNA
CTD
PMID:15498508
NCBI chr 1:32,640,372...32,682,669
Ensembl chr 1:32,640,407...32,679,898
G
Ier3
immediate early response 3
increases expression
ISO
tamibarotene results in increased expression of IER3 mRNA
CTD
PMID:15498508
NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
G
Ifi35
interferon-induced protein 35
increases expression
ISO
tamibarotene results in increased expression of IFI35 mRNA
CTD
PMID:15498508
NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952
G
Ifit3
interferon-induced protein with tetratricopeptide repeats 3
increases expression
ISO
tamibarotene results in increased expression of IFIT3 mRNA
CTD
PMID:15498508
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
G
Ifng
interferon gamma
multiple interactions decreases expression increases response to substance
ISO EXP
tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein] tamibarotene results in decreased expression of IFNG; tamibarotene results in decreased expression of IFNG protein IFNG results in increased susceptibility to tamibarotene tamibarotene results in decreased expression of IFNG mRNA tamibarotene inhibits the reaction [MBP results in increased expression of IFNG mRNA]
CTD
PMID:10828746 PMID:11043609 PMID:11501064 PMID:20861477 PMID:22077062
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Igfbp2
insulin-like growth factor binding protein 2
affects expression
ISO
tamibarotene affects the expression of IGFBP2 mRNA
CTD
PMID:15498508
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
G
Igfbp3
insulin-like growth factor binding protein 3
increases expression
ISO
tamibarotene results in increased expression of IGFBP3 mRNA; tamibarotene results in increased expression of IGFBP3 protein
CTD
PMID:10766424
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
G
Ighg1
immunoglobulin heavy constant gamma 1
affects expression
ISO
tamibarotene affects the expression of IGHG1 mRNA
CTD
PMID:15498508
Ensembl chr 6:132,389,370...132,393,397
G
Ikzf1
IKAROS family zinc finger 1
affects expression
ISO
tamibarotene affects the expression of IKZF1 mRNA
CTD
PMID:15498508
NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
G
Il10
interleukin 10
multiple interactions
EXP
tamibarotene inhibits the reaction [MBP results in increased expression of IL10 mRNA]
CTD
PMID:11501064
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il10rb
interleukin 10 receptor subunit beta
increases expression
ISO
tamibarotene results in increased expression of IL10RB mRNA
CTD
PMID:15498508
NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074
G
Il17a
interleukin 17A
multiple interactions
ISO
IL17A affects the reaction [tamibarotene results in decreased expression of TGFB1 mRNA]
CTD
PMID:22077062
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
G
Il17rd
interleukin 17 receptor D
decreases expression
ISO
tamibarotene results in decreased expression of IL17RD mRNA
CTD
PMID:20861477
NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556
G
Il1b
interleukin 1 beta
multiple interactions increases expression decreases expression
ISO
tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 protein] tamibarotene results in increased expression of IL1B mRNA tamibarotene results in decreased expression of IL1B mRNA
CTD
PMID:9873234 PMID:15498508 PMID:20861477
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il21
interleukin 21
multiple interactions
ISO
tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein]
CTD
PMID:22077062
NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
G
Il27
interleukin 27
decreases expression
ISO
tamibarotene results in decreased expression of IL27 mRNA
CTD
PMID:20861477
NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
G
Il2rg
interleukin 2 receptor subunit gamma
decreases expression
ISO
tamibarotene results in decreased expression of IL2RG mRNA
CTD
PMID:20861477
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
G
Il4
interleukin 4
multiple interactions
EXP
HX 600 promotes the reaction [tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 protein]]; LE 540 inhibits the reaction [tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 protein]]; tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 mRNA]; tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 protein]
CTD
PMID:11233995
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il6
interleukin 6
multiple interactions decreases expression
ISO EXP
tamibarotene inhibits the reaction [AGT protein results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [AGT protein results in increased secretion of IL6 protein]; tamibarotene inhibits the reaction [Lipopolysaccharides results in increased expression of IL6]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein] tamibarotene results in decreased expression of IL6 mRNA tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 protein] tamibarotene affects the reaction [MBP results in increased expression of IL6 mRNA]
CTD
PMID:9873234 PMID:10828746 PMID:11043609 PMID:11501064 PMID:16484594 PMID:17229644 More...
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Il6r
interleukin 6 receptor
decreases expression
ISO
tamibarotene results in decreased expression of IL6RA protein
CTD
PMID:20861477
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
G
Il7
interleukin 7
decreases expression
ISO
tamibarotene results in decreased expression of IL7 mRNA
CTD
PMID:20861477
NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
G
Il7r
interleukin 7 receptor
decreases expression
ISO
tamibarotene results in decreased expression of IL7R mRNA
CTD
PMID:20861477
NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
G
Ilf3
interleukin enhancer binding factor 3
decreases expression
ISO
tamibarotene results in decreased expression of ILF3 mRNA
CTD
PMID:15498508
NCBI chr 8:19,922,409...19,960,495
Ensembl chr 8:19,922,460...19,960,350
G
Ilk
integrin-linked kinase
increases expression
ISO
tamibarotene results in increased expression of ILK mRNA
CTD
PMID:15498508
NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
G
Ipo5
importin 5
affects expression
ISO
tamibarotene affects the expression of IPO5 mRNA
CTD
PMID:15498508
NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126
G
Irak2
interleukin-1 receptor-associated kinase 2
increases expression
ISO
tamibarotene results in increased expression of IRAK2 mRNA
CTD
PMID:17229644
NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
G
Irf1
interferon regulatory factor 1
increases expression
ISO
tamibarotene results in increased expression of IRF1 mRNA
CTD
PMID:15498508 PMID:17229644
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
G
Irf7
interferon regulatory factor 7
increases expression
ISO
tamibarotene results in increased expression of IRF7 mRNA
CTD
PMID:15498508
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
G
Irf9
interferon regulatory factor 9
increases expression
ISO
tamibarotene results in increased expression of IRF9 mRNA
CTD
PMID:15498508
NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236
G
Isg15
ISG15 ubiquitin-like modifier
affects expression
ISO
tamibarotene affects the expression of ISG15 mRNA
CTD
PMID:15498508
NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
G
Isg20
interferon stimulated exonuclease gene 20
affects expression
ISO
tamibarotene affects the expression of ISG20 mRNA
CTD
PMID:15498508
NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
G
Itga3
integrin subunit alpha 3
increases expression
ISO
tamibarotene results in increased expression of ITGA3 mRNA
CTD
PMID:17229644
NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
G
Itga4
integrin subunit alpha 4
affects expression
ISO
tamibarotene affects the expression of ITGA4 mRNA
CTD
PMID:15498508
NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
G
Itgam
integrin subunit alpha M
increases expression affects expression multiple interactions
ISO
tamibarotene results in increased expression of ITGAM mRNA; tamibarotene results in increased expression of ITGAM protein tamibarotene affects the expression of ITGAM protein CSF3 protein inhibits the reaction [tamibarotene results in increased expression of ITGAM mRNA]; Triiodothyronine promotes the reaction [tamibarotene results in increased expression of ITGAM protein]
CTD
PMID:11201846 PMID:15498508 PMID:21393419 PMID:27737899
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
G
Itgb2
integrin subunit beta 2
increases expression decreases expression multiple interactions
ISO
tamibarotene results in increased expression of ITGB2 mRNA tamibarotene results in decreased expression of ITGB2 mRNA CSF3 protein inhibits the reaction [tamibarotene results in decreased expression of ITGB2 mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in increased expression of ITGB2 mRNA]
CTD
PMID:15498508 PMID:27737899
NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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Itgb7
integrin subunit beta 7
increases expression
ISO
tamibarotene results in increased expression of ITGB7 mRNA
CTD
PMID:15498508 PMID:17229644
NCBI chr 7:133,347,927...133,364,955
Ensembl chr 7:133,347,960...133,364,876
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Itpr2
inositol 1,4,5-trisphosphate receptor, type 2
affects expression
ISO
tamibarotene affects the expression of ITPR2 mRNA
CTD
PMID:15498508
NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
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Itpr3
inositol 1,4,5-trisphosphate receptor, type 3
decreases expression
ISO
tamibarotene results in decreased expression of ITPR3 mRNA
CTD
PMID:15498508
NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
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Jak1
Janus kinase 1
affects expression
ISO
tamibarotene affects the expression of JAK1 mRNA
CTD
PMID:15498508
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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Jak3
Janus kinase 3
decreases expression
ISO
tamibarotene results in decreased expression of JAK3 mRNA
CTD
PMID:20861477
NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
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Kat5
lysine acetyltransferase 5
increases expression
ISO
tamibarotene results in increased expression of KAT5 mRNA
CTD
PMID:15498508
NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
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Kcnab2
potassium voltage-gated channel subfamily A regulatory beta subunit 2
affects expression
ISO
tamibarotene affects the expression of KCNAB2 mRNA
CTD
PMID:15498508
NCBI chr 5:162,899,511...162,988,057
Ensembl chr 5:162,901,896...162,988,243
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Kdm5b
lysine demethylase 5B
affects expression
ISO
tamibarotene affects the expression of KDM5B mRNA
CTD
PMID:15498508
NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
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Kif2a
kinesin family member 2A
decreases expression
ISO
tamibarotene results in decreased expression of KIF2A mRNA
CTD
PMID:15498508
NCBI chr 2:38,367,998...38,431,237
Ensembl chr 2:38,367,998...38,431,508
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Klf10
KLF transcription factor 10
decreases expression
ISO
tamibarotene results in decreased expression of KLF10 mRNA
CTD
PMID:15498508
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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Klf5
KLF transcription factor 5
multiple interactions
ISO
tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to [RARA protein binds to RXRA protein]]; tamibarotene inhibits the reaction [KLF5 protein binds to PDGFA promoter]; tamibarotene inhibits the reaction [KLF5 results in increased expression of PDGFA mRNA]
CTD
PMID:16224062
NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
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Klf9
KLF transcription factor 9
decreases expression
ISO
tamibarotene results in decreased expression of KLF9 mRNA
CTD
PMID:15498508
NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037
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Kmt2b
lysine methyltransferase 2B
affects expression
ISO
tamibarotene affects the expression of KMT2B mRNA
CTD
PMID:15498508
NCBI chr 1:85,821,700...85,840,987
Ensembl chr 1:85,821,753...85,841,326
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Lamc1
laminin subunit gamma 1
decreases expression
ISO
tamibarotene results in decreased expression of LAMC1 mRNA
CTD
PMID:15498508
NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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Lasp1
LIM and SH3 protein 1
increases expression
ISO
tamibarotene results in increased expression of LASP1 mRNA
CTD
PMID:15498508
NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292
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Lck
LCK proto-oncogene, Src family tyrosine kinase
increases expression
ISO
tamibarotene results in increased expression of LCK mRNA
CTD
PMID:15498508
NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
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Lcp2
lymphocyte cytosolic protein 2
increases expression
ISO
tamibarotene results in increased expression of LCP2 mRNA
CTD
PMID:15498508
NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559
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Lgals1
galectin 1
increases expression
ISO
tamibarotene results in increased expression of LGALS1 mRNA
CTD
PMID:15498508
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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Lgals9
galectin 9
increases expression
ISO
tamibarotene results in increased expression of LGALS9 mRNA
CTD
PMID:15498508
NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
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Lmnb1
lamin B1
affects expression
ISO
tamibarotene affects the expression of LMNB1 mRNA
CTD
PMID:15498508
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
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Lpin1
lipin 1
decreases expression
ISO
tamibarotene results in decreased expression of LPIN1 mRNA
CTD
PMID:15498508
NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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Lrba
LPS responsive beige-like anchor protein
affects expression
ISO
tamibarotene affects the expression of LRBA mRNA
CTD
PMID:15498508
NCBI chr 2:171,623,668...172,202,576
Ensembl chr 2:171,621,507...172,202,724
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Lsm14a
LSM14A mRNA processing body assembly factor
decreases expression
ISO
tamibarotene results in decreased expression of LSM14A mRNA
CTD
PMID:15498508
NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276
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Lsp1
lymphocyte-specific protein 1
increases expression
ISO
tamibarotene results in increased expression of LSP1 mRNA
CTD
PMID:15498508
NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416
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Lst1
leukocyte specific transcript 1
increases expression
ISO
tamibarotene results in increased expression of LST1 mRNA
CTD
PMID:15498508
NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997
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Ltb4r
leukotriene B4 receptor
affects expression
ISO
tamibarotene affects the expression of LTB4R mRNA
CTD
PMID:15498508
NCBI chr15:29,263,199...29,265,716
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Ly6e
lymphocyte antigen 6 family member E
increases expression
ISO
tamibarotene results in increased expression of LY6E mRNA
CTD
PMID:15498508
NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
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Lyn
LYN proto-oncogene, Src family tyrosine kinase
increases expression
ISO
tamibarotene results in increased expression of LYN mRNA
CTD
PMID:15498508
NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
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Lztfl1
leucine zipper transcription factor-like 1
increases expression
ISO
tamibarotene results in increased expression of LZTFL1 mRNA
CTD
PMID:17229644
NCBI chr 8:123,344,085...123,360,245
Ensembl chr 8:123,344,925...123,360,192
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Macf1
microtubule-actin crosslinking factor 1
affects expression
ISO
tamibarotene affects the expression of MACF1 mRNA
CTD
PMID:15498508
NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905
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Macir
macrophage immunometabolism regulator
decreases expression
ISO
tamibarotene results in decreased expression of MACIR mRNA
CTD
PMID:15498508
NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733
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Map4k1
mitogen activated protein kinase kinase kinase kinase 1
increases expression
ISO
tamibarotene results in increased expression of MAP4K1 mRNA
CTD
PMID:17229644
NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493
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Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation
ISO EXP
[tamibarotene co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; tamibarotene promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of and results in decreased activity of MAPK1 protein] BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK1 protein]
CTD
PMID:15020266 PMID:19457078
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk14
mitogen activated protein kinase 14
affects expression
ISO
tamibarotene affects the expression of MAPK14 mRNA
CTD
PMID:15498508
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation
ISO EXP
[tamibarotene co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; tamibarotene promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of and results in decreased activity of MAPK3 protein] BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK3 protein]
CTD
PMID:15020266 PMID:19457078
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapkapk2
MAPK activated protein kinase 2
increases expression
ISO
tamibarotene results in increased expression of MAPKAPK2 mRNA
CTD
PMID:17229644
NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
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Mat2a
methionine adenosyltransferase 2A
decreases expression
ISO
tamibarotene results in decreased expression of MAT2A mRNA
CTD
PMID:15498508
NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
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Mbp
myelin basic protein
multiple interactions increases expression
EXP
tamibarotene affects the reaction [MBP results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of IFNG mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of IL10 mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of NOS2 mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of TNF mRNA] tamibarotene results in increased expression of MBP
CTD
PMID:11501064 PMID:19182380
NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
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Mdk
midkine
increases expression
ISO
tamibarotene results in increased expression of MDK mRNA
CTD
PMID:17229644
NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
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Mdm1
Mdm1 nuclear protein
decreases expression
ISO
tamibarotene results in decreased expression of MDM1 mRNA
CTD
PMID:15498508
NCBI chr 7:53,729,603...53,766,034
Ensembl chr 7:53,729,610...53,766,034
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Mdn1
midasin AAA ATPase 1
affects expression
ISO
tamibarotene affects the expression of MDN1 mRNA
CTD
PMID:15498508
NCBI chr 5:47,055,435...47,190,426
Ensembl chr 5:47,055,447...47,186,332
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Med21
mediator complex subunit 21
affects expression
ISO
tamibarotene affects the expression of MED21 mRNA
CTD
PMID:15498508
NCBI chr 4:179,560,509...179,583,811
Ensembl chr 4:179,560,579...179,567,548
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Mfap3
microfibril associated protein 3
affects expression
ISO
tamibarotene affects the expression of MFAP3 mRNA
CTD
PMID:15498508
NCBI chr10:41,696,788...41,711,490
Ensembl chr10:41,696,771...41,710,406
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Mfge8
milk fat globule EGF and factor V/VIII domain containing
increases expression
ISO
tamibarotene results in increased expression of MFGE8 mRNA
CTD
PMID:17229644
NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
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Morc2
MORC family CW-type zinc finger 2
decreases expression
ISO
tamibarotene results in decreased expression of MORC2 mRNA
CTD
PMID:15498508
NCBI chr14:78,529,603...78,571,375
Ensembl chr14:78,527,009...78,571,343
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Msh6
mutS homolog 6
decreases expression
ISO
tamibarotene results in decreased expression of MSH6 mRNA
CTD
PMID:15498508
NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
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Msi1
musashi RNA-binding protein 1
affects expression
ISO
tamibarotene affects the expression of MSI1 mRNA
CTD
PMID:15498508
NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076
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Msr1
macrophage scavenger receptor 1
multiple interactions
ISO
tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]
CTD
PMID:16484594
NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
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Mt1
metallothionein 1
increases expression
ISO
tamibarotene results in increased expression of MT1A mRNA
CTD
PMID:15498508
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
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Mt3
metallothionein 3
affects expression
ISO
tamibarotene affects the expression of MT3 mRNA
CTD
PMID:15498508
NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
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Mta1
metastasis associated 1
decreases expression
ISO
tamibarotene results in decreased expression of MTA1 mRNA
CTD
PMID:15498508
NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
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Mtg1
mitochondrial ribosome-associated GTPase 1
affects expression
ISO
tamibarotene affects the expression of MTG1 mRNA
CTD
PMID:15498508
NCBI chr 1:194,931,543...194,944,278
Ensembl chr 1:194,931,531...194,944,277
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Mtmr6
myotubularin related protein 6
decreases expression
ISO
tamibarotene results in decreased expression of MTMR6 mRNA
CTD
PMID:15498508
NCBI chr15:34,419,931...34,457,863
Ensembl chr15:34,419,903...34,457,861
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Mx2
MX dynamin like GTPase 2
affects expression
ISO
tamibarotene affects the expression of MX2 mRNA
CTD
PMID:15498508
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
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Myb
MYB proto-oncogene, transcription factor
affects expression
ISO
tamibarotene affects the expression of MYB mRNA
CTD
PMID:15498508
NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression
ISO
tamibarotene results in decreased expression of MYC mRNA
CTD
PMID:15498508
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myd88
MYD88, innate immune signal transduction adaptor
increases expression
ISO
tamibarotene results in increased expression of MYD88 mRNA
CTD
PMID:15498508
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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N4bp2l2
NEDD4 binding protein 2-like 2
decreases expression
ISO
tamibarotene results in decreased expression of N4BP2L2 mRNA
CTD
PMID:15498508
NCBI chr12:137,342...200,292
Ensembl chr12:103,590...197,784
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Nap1l1
nucleosome assembly protein 1-like 1
decreases expression
ISO
tamibarotene results in decreased expression of NAP1L1 mRNA
CTD
PMID:15498508
NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
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Ncbp2
nuclear cap binding protein subunit 2
decreases expression
ISO
tamibarotene results in decreased expression of NCBP2 mRNA
CTD
PMID:15498508
NCBI chr11:68,821,026...68,829,863
Ensembl chr11:68,817,740...68,851,885
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Ncf1
neutrophil cytosolic factor 1
increases expression
ISO
tamibarotene results in increased expression of NCF1 mRNA
CTD
PMID:15498508
NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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Nck1
NCK adaptor protein 1
affects expression
ISO
tamibarotene affects the expression of NCK1 mRNA
CTD
PMID:15498508
NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
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Ncoa6
nuclear receptor coactivator 6
decreases expression
ISO
tamibarotene results in decreased expression of NCOA6 mRNA
CTD
PMID:15498508
NCBI chr 3:143,890,896...143,961,916
Ensembl chr 3:143,890,896...143,952,268
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Ncor2
nuclear receptor co-repressor 2
increases expression
ISO
tamibarotene results in increased expression of NCOR2 mRNA
CTD
PMID:17229644
NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
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Nemp1
nuclear envelope integral membrane protein 1
decreases expression
ISO
tamibarotene results in decreased expression of NEMP1 mRNA
CTD
PMID:15498508
NCBI chr 7:63,514,025...63,538,791
Ensembl chr 7:63,479,951...63,534,602
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Nfe2
nuclear factor, erythroid 2
increases expression
ISO
tamibarotene results in increased expression of NFE2 mRNA
CTD
PMID:15498508
NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
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Nfe2l2
NFE2 like bZIP transcription factor 2
decreases expression
ISO
tamibarotene results in decreased expression of NFE2L2 mRNA
CTD
PMID:15498508
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfyb
nuclear transcription factor Y subunit beta
decreases expression
ISO
tamibarotene results in decreased expression of NFYB mRNA
CTD
PMID:15498508
NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565
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Nherf1
NHERF family PDZ scaffold protein 1
increases expression
ISO
tamibarotene results in increased expression of NHERF1 mRNA
CTD
PMID:15498508
NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
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Nipsnap1
nipsnap homolog 1
increases expression
ISO
tamibarotene results in increased expression of NIPSNAP1 mRNA
CTD
PMID:15498508
NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098
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Nkg7
natural killer cell granule protein 7
increases expression
ISO
tamibarotene results in increased expression of NKG7 mRNA
CTD
PMID:15498508
NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
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Nkrf
NFKB repressing factor
increases expression
ISO
tamibarotene results in increased expression of NKRF mRNA
CTD
PMID:20861477
NCBI chr X:116,126,341...116,144,554
Ensembl chr X:116,128,798...116,144,628
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Nos2
nitric oxide synthase 2
multiple interactions
EXP
tamibarotene inhibits the reaction [MBP results in increased expression of NOS2 mRNA]
CTD
PMID:11501064
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Npc2
NPC intracellular cholesterol transporter 2
increases expression
ISO
tamibarotene results in increased expression of NPC2 mRNA
CTD
PMID:15498508
NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
increases activity multiple interactions
ISO
tamibarotene results in increased activity of NR1H4 protein tamibarotene inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]
CTD
PMID:25257666
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Nr2f2
nuclear receptor subfamily 2, group F, member 2
decreases expression
ISO
tamibarotene results in decreased expression of NR2F2 mRNA
CTD
PMID:15498508
NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
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Ntrk2
neurotrophic receptor tyrosine kinase 2
multiple interactions increases phosphorylation increases expression
ISO EXP
[tamibarotene co-treated with BDNF] results in increased expression of NTRK2 tamibarotene results in increased phosphorylation of NTRK2 protein BDNF affects the reaction [tamibarotene results in increased phosphorylation of NTRK2 protein] tamibarotene results in increased expression of NTRK2
CTD
PMID:19182380 PMID:19457078
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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Nudt21
nudix hydrolase 21
affects expression
ISO
tamibarotene affects the expression of NUDT21 mRNA
CTD
PMID:15498508
NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682
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Nutf2
nuclear transport factor 2
affects expression
ISO
tamibarotene affects the expression of NUTF2 mRNA
CTD
PMID:15498508
NCBI chr19:33,752,319...33,773,595
Ensembl chr19:33,752,291...33,773,591
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Oas1a
2'-5' oligoadenylate synthetase 1A
affects expression
ISO
tamibarotene affects the expression of OAS1 mRNA
CTD
PMID:15498508
NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
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Oas2
2'-5' oligoadenylate synthetase 2
increases expression
ISO
tamibarotene results in increased expression of OAS2 mRNA
CTD
PMID:15498508
NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
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Oasl
2'-5'-oligoadenylate synthetase-like
increases expression
ISO
tamibarotene results in increased expression of OASL mRNA
CTD
PMID:15498508
NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
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Ocln
occludin
increases expression
ISO
tamibarotene results in increased expression of OCLN mRNA
CTD
PMID:16982755
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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Odc1
ornithine decarboxylase 1
decreases expression
ISO
tamibarotene results in decreased expression of ODC1 mRNA
CTD
PMID:15498508
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
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Oga
O-GlcNAcase
decreases expression
ISO
tamibarotene results in decreased expression of OGA mRNA
CTD
PMID:15498508
NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
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Ogg1
8-oxoguanine DNA glycosylase
increases expression
ISO
tamibarotene results in increased expression of OGG1 mRNA
CTD
PMID:15498508
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
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Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase
decreases expression
ISO
tamibarotene results in decreased expression of OGT mRNA
CTD
PMID:15498508
NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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Orc2
origin recognition complex, subunit 2
decreases expression
ISO
tamibarotene results in decreased expression of ORC2 mRNA
CTD
PMID:15498508
NCBI chr 9:60,001,631...60,038,301
Ensembl chr 9:60,001,910...60,038,195
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P2rx5
purinergic receptor P2X 5
increases expression
ISO
tamibarotene results in increased expression of P2RX5 mRNA
CTD
PMID:17229644
NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
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P2ry14
purinergic receptor P2Y14
increases expression
ISO
tamibarotene results in increased expression of P2RY14 mRNA
CTD
PMID:15498508
NCBI chr 2:143,372,697...143,413,213
Ensembl chr 2:143,372,697...143,413,141
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Pak1
p21 (RAC1) activated kinase 1
increases expression
ISO
tamibarotene results in increased expression of PAK1 mRNA
CTD
PMID:15498508
NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
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Pak2
p21 (RAC1) activated kinase 2
affects expression
ISO
tamibarotene affects the expression of PAK2 mRNA
CTD
PMID:15498508
NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816
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Pakap
paralemmin A kinase anchor protein
affects expression
ISO
tamibarotene affects the expression of PALM2AKAP2 mRNA
CTD
PMID:15498508
NCBI chr 5:72,536,986...72,648,524 NCBI chr 5:72,313,646...72,450,645
Ensembl chr 5:72,181,718...72,648,524
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Pank3
pantothenate kinase 3
affects expression
ISO
tamibarotene affects the expression of PANK3 mRNA
CTD
PMID:15498508
NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955
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Papola
poly (A) polymerase alpha
affects expression
ISO
tamibarotene affects the expression of PAPOLA mRNA
CTD
PMID:15498508
NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
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Pcdh1
protocadherin 1
affects expression
ISO
tamibarotene affects the expression of PCDH1 mRNA
CTD
PMID:15498508
NCBI chr18:30,011,692...30,039,679
Ensembl chr18:30,013,185...30,039,318
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Pcmt1
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
affects expression
ISO
tamibarotene affects the expression of PCMT1 mRNA
CTD
PMID:15498508
NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
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Pcna
proliferating cell nuclear antigen
affects expression
ISO
tamibarotene affects the expression of PCNA mRNA
CTD
PMID:15498508
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pdgfa
platelet derived growth factor subunit A
multiple interactions
ISO
tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to PDGFA promoter]; tamibarotene inhibits the reaction [KLF5 results in increased expression of PDGFA mRNA]; tamibarotene inhibits the reaction [RARA protein binds to PDGFA promoter]; tamibarotene inhibits the reaction [RXRA protein binds to PDGFA promoter]
CTD
PMID:16224062
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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Pdhx
pyruvate dehydrogenase complex, component X
affects expression
ISO
tamibarotene affects the expression of PDHX mRNA
CTD
PMID:15498508
NCBI chr 3:89,372,248...89,431,779
Ensembl chr 3:89,371,497...89,431,773
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Pgd
phosphogluconate dehydrogenase
increases expression
ISO
tamibarotene results in increased expression of PGD mRNA
CTD
PMID:15498508
NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
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Phyhip
phytanoyl-CoA 2-hydroxylase interacting protein
decreases expression
ISO
tamibarotene results in decreased expression of PHYHIP mRNA
CTD
PMID:15498508
NCBI chr15:45,533,974...45,545,223
Ensembl chr15:45,533,974...45,545,221
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Pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
affects expression
ISO
tamibarotene affects the expression of PIK3CB mRNA
CTD
PMID:15498508
NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
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Pik3cd
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
increases expression
ISO
tamibarotene results in increased expression of PIK3CD mRNA
CTD
PMID:15498508
NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
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Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
multiple interactions increases expression
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of and results in increased activity of PIK3CG protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of PIK3CG mRNA]; tamibarotene results in increased expression of and results in increased activity of PIK3CG protein
CTD
PMID:15020266 PMID:15498508
NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
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Pikfyve
phosphoinositide kinase, FYVE-type zinc finger containing
decreases expression
ISO
tamibarotene results in decreased expression of PIKFYVE mRNA
CTD
PMID:15498508
NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868
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Pim1
Pim-1 proto-oncogene, serine/threonine kinase
increases expression
ISO
tamibarotene results in increased expression of PIM1 mRNA
CTD
PMID:15498508
NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
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Pitpnb
phosphatidylinositol transfer protein, beta
affects expression
ISO
tamibarotene affects the expression of PITPNB mRNA
CTD
PMID:15498508
NCBI chr12:45,249,308...45,298,388
Ensembl chr12:45,249,333...45,298,314
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Pkn1
protein kinase N1
increases expression
ISO
tamibarotene results in increased expression of PKN1 mRNA
CTD
PMID:15498508
NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107
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Pkp4
plakophilin 4
decreases expression
ISO
tamibarotene results in decreased expression of PKP4 mRNA
CTD
PMID:15498508
NCBI chr 3:43,632,364...43,835,834
Ensembl chr 3:43,631,880...43,835,474
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Plek
pleckstrin
increases expression
ISO
tamibarotene results in increased expression of PLEK mRNA
CTD
PMID:15498508 PMID:17229644
NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
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Plk4
polo-like kinase 4
decreases expression
ISO
tamibarotene results in decreased expression of PLK4 mRNA
CTD
PMID:15498508
NCBI chr 2:123,802,527...123,820,942
Ensembl chr 2:123,802,512...123,820,942
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Plscr1
phospholipid scramblase 1
increases expression
ISO
tamibarotene results in increased expression of PLSCR1 mRNA
CTD
PMID:15498508
NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
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Plxna1
plexin A1
increases expression
ISO
tamibarotene results in increased expression of PLXNA1 mRNA
CTD
PMID:17229644
NCBI chr 4:121,737,934...121,782,901
Ensembl chr 4:121,737,945...122,024,196
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Pnn
pinin, desmosome associated protein
decreases expression
ISO
tamibarotene results in decreased expression of PNN mRNA
CTD
PMID:15498508
NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889
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Pold4
DNA polymerase delta 4, accessory subunit
increases expression
ISO
tamibarotene results in increased expression of POLD4 mRNA
CTD
PMID:15498508
NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401
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Por
cytochrome p450 oxidoreductase
increases expression
ISO
tamibarotene results in increased expression of POR mRNA
CTD
PMID:15498508
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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Ppat
phosphoribosyl pyrophosphate amidotransferase
decreases expression
ISO
tamibarotene results in decreased expression of PPAT mRNA
CTD
PMID:15498508
NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144
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Ppfia1
PTPRF interacting protein alpha 1
decreases expression
ISO
tamibarotene results in decreased expression of PPFIA1 mRNA
CTD
PMID:15498508
NCBI chr 1:199,641,277...199,718,371
Ensembl chr 1:199,641,277...199,717,277
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Ppp1cb
protein phosphatase 1 catalytic subunit beta
decreases expression
ISO
tamibarotene results in decreased expression of PPP1CB mRNA
CTD
PMID:15498508
NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
tamibarotene results in increased expression of PPP1R15A mRNA
CTD
PMID:17229644
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Ppp2r1b
protein phosphatase 2 scaffold subunit A beta
affects expression
ISO
tamibarotene affects the expression of PPP2R1B mRNA
CTD
PMID:15498508
NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
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Prdm2
PR/SET domain 2
affects expression
ISO
tamibarotene affects the expression of PRDM2 mRNA
CTD
PMID:15498508
NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825
G
Prkaca
protein kinase cAMP-activated catalytic subunit alpha
increases expression
ISO
tamibarotene results in increased expression of PRKACA mRNA
CTD
PMID:17229644
NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
G
Prkacb
protein kinase cAMP-activated catalytic subunit beta
decreases expression
ISO
tamibarotene results in decreased expression of PRKACB mRNA
CTD
PMID:15498508
NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
G
Prkcb
protein kinase C, beta
increases expression
ISO
tamibarotene results in increased expression of PRKCB mRNA
CTD
PMID:15498508
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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Prkcd
protein kinase C, delta
increases expression
ISO
tamibarotene results in increased expression of PRKCD mRNA
CTD
PMID:15498508
NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
G
Prkci
protein kinase C, iota
decreases expression
ISO
tamibarotene results in decreased expression of PRKCI mRNA
CTD
PMID:15498508
NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
G
Prkdc
protein kinase, DNA-activated, catalytic subunit
decreases expression affects expression
ISO
tamibarotene results in decreased expression of PRKDC mRNA tamibarotene affects the expression of PRKDC mRNA
CTD
PMID:15498508
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
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Prmt2
protein arginine methyltransferase 2
increases expression
ISO
tamibarotene results in increased expression of PRMT2 mRNA
CTD
PMID:15498508
NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643
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Prnp
prion protein
affects expression
ISO
tamibarotene affects the expression of PRNP mRNA
CTD
PMID:15498508
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Prpf40a
pre-mRNA processing factor 40 homolog A
affects expression
ISO
tamibarotene affects the expression of PRPF40A mRNA
CTD
PMID:15498508
NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
G
Prps1
phosphoribosyl pyrophosphate synthetase 1
affects expression
ISO
tamibarotene affects the expression of PRPS1 mRNA
CTD
PMID:15498508
NCBI chr X:104,132,139...104,154,191
Ensembl chr X:104,132,141...104,154,187
G
Prrc2c
proline-rich coiled-coil 2C
decreases expression
ISO
tamibarotene results in decreased expression of PRRC2C mRNA
CTD
PMID:15498508
NCBI chr13:75,003,995...75,073,701
Ensembl chr13:75,004,010...75,073,643
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Prtn3
proteinase 3
increases expression
ISO
tamibarotene results in increased expression of PRTN3 mRNA
CTD
PMID:17229644
NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944
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Psmb9
proteasome 20S subunit beta 9
increases expression
ISO
tamibarotene results in increased expression of PSMB9 mRNA
CTD
PMID:15498508
NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
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Psme2
proteasome activator subunit 2
increases expression
ISO
tamibarotene results in increased expression of PSME2 mRNA
CTD
PMID:15498508
NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946
G
Ptk2b
protein tyrosine kinase 2 beta
increases expression
ISO
tamibarotene results in increased expression of PTK2B mRNA
CTD
PMID:15498508
NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
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Ptpn3
protein tyrosine phosphatase, non-receptor type 3
affects expression
ISO
tamibarotene affects the expression of PTPN3 mRNA
CTD
PMID:15498508
NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443
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Ptprc
protein tyrosine phosphatase, receptor type, C
decreases expression
ISO
tamibarotene results in decreased expression of PTPRC mRNA
CTD
PMID:17229644
NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
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Ptprf
protein tyrosine phosphatase, receptor type, F
decreases expression
ISO
tamibarotene results in decreased expression of PTPRF mRNA
CTD
PMID:15498508
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
G
Ptprn
protein tyrosine phosphatase, receptor type, N
affects expression
ISO
tamibarotene affects the expression of PTPRN mRNA
CTD
PMID:15498508
NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
G
Pum1
pumilio RNA-binding family member 1
decreases expression
ISO
tamibarotene results in decreased expression of PUM1 mRNA
CTD
PMID:15498508
NCBI chr 5:142,836,933...142,954,331
Ensembl chr 5:142,837,127...142,954,039
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Rab1a
RAB1A, member RAS oncogene family
affects expression
ISO
tamibarotene affects the expression of RAB1A mRNA
CTD
PMID:15498508
NCBI chr14:94,422,219...94,448,799
Ensembl chr14:94,415,275...94,448,248
G
Rab31
RAB31, member RAS oncogene family
increases expression
ISO
tamibarotene results in increased expression of RAB31 mRNA
CTD
PMID:15498508
NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
G
Rab35
RAB35, member RAS oncogene family
affects expression
ISO
tamibarotene affects the expression of RAB35 mRNA
CTD
PMID:15498508
NCBI chr12:40,967,102...40,981,183
Ensembl chr12:40,967,103...40,991,195
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Rab3gap1
RAB3 GTPase activating protein catalytic subunit 1
decreases expression
ISO
tamibarotene results in decreased expression of RAB3GAP1 mRNA
CTD
PMID:15498508
NCBI chr13:39,355,698...39,429,154
Ensembl chr13:39,352,247...39,429,169
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Rab4a
RAB4A, member RAS oncogene family
decreases expression
ISO
tamibarotene results in decreased expression of RAB4A mRNA
CTD
PMID:15498508
NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703
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Rab5a
RAB5A, member RAS oncogene family
affects expression
ISO
tamibarotene affects the expression of RAB5A mRNA
CTD
PMID:15498508
NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
G
Rab5c
RAB5C, member RAS oncogene family
increases expression
ISO
tamibarotene results in increased expression of RAB5C mRNA
CTD
PMID:15498508
NCBI chr10:85,642,553...85,666,142
Ensembl chr10:85,642,809...85,666,103
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Rab6a
RAB6A, member RAS oncogene family
affects expression
ISO
tamibarotene affects the expression of RAB6A mRNA
CTD
PMID:15498508
NCBI chr 1:154,957,870...155,008,922
Ensembl chr 1:154,958,189...154,996,715
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Rabggtb
Rab geranylgeranyltransferase subunit beta
decreases expression
ISO
tamibarotene results in decreased expression of RABGGTB mRNA
CTD
PMID:15498508
NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050
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Rad50
RAD50 double strand break repair protein
affects expression
ISO
tamibarotene affects the expression of RAD50 mRNA
CTD
PMID:15498508
NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
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Rara
retinoic acid receptor, alpha
multiple interactions decreases response to substance increases expression
ISO EXP
tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to [RARA protein binds to RXRA protein]]; tamibarotene inhibits the reaction [RARA protein binds to PDGFA promoter] RARA results in decreased susceptibility to tamibarotene tamibarotene results in increased expression of RARA protein
CTD
PMID:16224062 PMID:17611697 PMID:19457078
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
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Rarb
retinoic acid receptor, beta
increases expression multiple interactions
ISO EXP
tamibarotene results in increased expression of RARB mRNA tamibarotene results in increased expression of RARB protein CSF3 protein promotes the reaction [tamibarotene results in increased expression of RARB mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of RARB mRNA]
CTD
PMID:16289102 PMID:19457078 PMID:27737899
NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
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Rarg
retinoic acid receptor, gamma
affects expression
ISO
tamibarotene affects the expression of RARG mRNA
CTD
PMID:7934625
NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
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Rassf6
Ras association domain family member 6
decreases expression
ISO
tamibarotene results in decreased expression of RASSF6 mRNA
CTD
PMID:17229644
NCBI chr14:17,433,328...17,473,565
Ensembl chr14:17,442,789...17,473,330
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Rbbp4
RB binding protein 4, chromatin remodeling factor
affects expression
ISO
tamibarotene affects the expression of RBBP4 mRNA
CTD
PMID:15498508
NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284 Ensembl chr 2:141,638,421...141,675,284
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Rcc1
regulator of chromosome condensation 1
decreases expression
ISO
tamibarotene results in decreased expression of RCC1 mRNA
CTD
PMID:15498508
NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
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Rela
RELA proto-oncogene, NF-kB subunit
affects expression
ISO
tamibarotene affects the expression of RELA mRNA
CTD
PMID:15498508
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Relb
RELB proto-oncogene, NF-kB subunit
increases expression
ISO
tamibarotene results in increased expression of RELB mRNA
CTD
PMID:17229644
NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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Rev3l
REV3 like, DNA directed polymerase zeta catalytic subunit
decreases expression
ISO
tamibarotene results in decreased expression of REV3L mRNA
CTD
PMID:15498508
NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099
G
Rfc5
replication factor C subunit 5
affects expression
ISO
tamibarotene affects the expression of RFC5 mRNA
CTD
PMID:15498508
NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
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Rgs16
regulator of G-protein signaling 16
decreases expression
ISO
tamibarotene results in decreased expression of RGS16 mRNA
CTD
PMID:15498508
NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
G
Rhbdd3
rhomboid domain containing 3
decreases expression
ISO
tamibarotene results in decreased expression of RHBDD3 mRNA
CTD
PMID:15498508
NCBI chr14:79,994,111...80,000,294
Ensembl chr14:79,994,158...80,000,175
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Rhoq
ras homolog family member Q
affects expression
ISO
tamibarotene affects the expression of RHOQ mRNA
CTD
PMID:15498508
NCBI chr 6:7,613,632...7,652,047
Ensembl chr 1:106,622,141...106,623,699
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Rhou
ras homolog family member U
decreases expression
ISO
tamibarotene results in decreased expression of RHOU mRNA
CTD
PMID:17229644
NCBI chr19:51,641,476...51,651,249
Ensembl chr19:51,641,227...51,650,552
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Rif1
replication timing regulatory factor 1
decreases expression
ISO
tamibarotene results in decreased expression of RIF1 mRNA
CTD
PMID:15498508
NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
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Rmnd5a
required for meiotic nuclear division 5 homolog A
decreases expression
ISO
tamibarotene results in decreased expression of RMND5A mRNA
CTD
PMID:15498508
NCBI chr 4:103,375,846...103,432,890
Ensembl chr 4:103,379,908...103,433,051
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Rnf115
ring finger protein 115
affects expression
ISO
tamibarotene affects the expression of RNF115 mRNA
CTD
PMID:15498508
NCBI chr 2:184,262,087...184,329,839
Ensembl chr 2:184,262,371...184,329,823
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Rnmt
RNA (guanine-7-) methyltransferase
affects expression
ISO
tamibarotene affects the expression of RNMT mRNA
CTD
PMID:15498508
NCBI chr18:61,886,230...61,909,775
Ensembl chr18:61,886,292...61,909,775
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Rps2
ribosomal protein S2
increases expression
ISO
tamibarotene results in increased expression of RPS2 mRNA
CTD
PMID:15498508
NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
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Rps6ka3
ribosomal protein S6 kinase A3
decreases expression
ISO
tamibarotene results in decreased expression of RPS6KA3 mRNA
CTD
PMID:15498508
NCBI chr X:35,517,306...35,623,296
Ensembl chr X:35,517,306...35,623,207
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Rps6kb1
ribosomal protein S6 kinase B1
affects expression
ISO
tamibarotene affects the expression of RPS6KB1 mRNA
CTD
PMID:15498508
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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Rrm2
ribonucleotide reductase regulatory subunit M2
affects expression
ISO
tamibarotene affects the expression of RRM2 mRNA
CTD
PMID:15498508
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
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RT1-A2
RT1 class Ia, locus A2
increases expression
ISO
tamibarotene results in increased expression of HLA-E mRNA
CTD
PMID:15498508
NCBI chr20:4,870,939...4,910,183
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RT1-Bb
RT1 class II, locus Bb
increases expression
ISO
tamibarotene results in increased expression of HLA-DQB1 mRNA
CTD
PMID:17229644
NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
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RT1-Da
RT1 class II, locus Da
increases expression
ISO
tamibarotene results in increased expression of HLA-DRA mRNA
CTD
PMID:17229644
NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
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RT1-DMa
RT1 class II, locus DMa
increases expression
ISO
tamibarotene results in increased expression of HLA-DMA mRNA
CTD
PMID:17229644
NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
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RT1-DMb
RT1 class II, locus DMb
increases expression
ISO
tamibarotene results in increased expression of HLA-DMB mRNA
CTD
PMID:17229644
NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
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RT1-Ha
RT1 class II, locus Ha
increases expression
ISO
tamibarotene results in increased expression of HLA-DPA1 mRNA
CTD
PMID:17229644
NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244
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RT1-M3-1
RT1 class Ib, locus M3, gene 1
increases expression
ISO
tamibarotene results in increased expression of HLA-G mRNA
CTD
PMID:15498508
NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
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Rtel1
regulator of telomere elongation helicase 1
affects expression
ISO
tamibarotene affects the expression of RTEL1 mRNA
CTD
PMID:15498508
NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348
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Runx1
RUNX family transcription factor 1
affects expression
ISO
tamibarotene affects the expression of RUNX1 mRNA
CTD
PMID:15498508
NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
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Runx2
RUNX family transcription factor 2
decreases expression
ISO
tamibarotene results in decreased expression of RUNX2 mRNA
CTD
PMID:15498508
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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Rxra
retinoid X receptor alpha
multiple interactions
ISO
tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to [RARA protein binds to RXRA protein]]; tamibarotene inhibits the reaction [RXRA protein binds to PDGFA promoter]
CTD
PMID:16224062
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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S100a4
S100 calcium-binding protein A4
decreases expression increases expression
ISO
tamibarotene results in decreased expression of S100A4 mRNA tamibarotene results in increased expression of S100A4 mRNA
CTD
PMID:15498508 PMID:17229644
NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
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S100a8
S100 calcium binding protein A8
increases expression
ISO
tamibarotene results in increased expression of S100A8 mRNA
CTD
PMID:15498508
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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S100a9
S100 calcium binding protein A9
increases expression
ISO
tamibarotene results in increased expression of S100A9 mRNA
CTD
PMID:15498508
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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Sacs
sacsin molecular chaperone
decreases expression
ISO
tamibarotene results in decreased expression of SACS mRNA
CTD
PMID:15498508
NCBI chr15:35,285,783...35,370,335
Ensembl chr15:35,285,782...35,370,335
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Sap30
Sin3A associated protein 30
decreases expression
ISO
tamibarotene results in decreased expression of SAP30 mRNA
CTD
PMID:15498508
NCBI chr16:32,747,777...32,753,114
Ensembl chr16:32,747,734...32,753,112
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Sat1
spermidine/spermine N1-acetyl transferase 1
increases expression
ISO
tamibarotene results in increased expression of SAT1 mRNA
CTD
PMID:15498508
NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
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Scamp1
secretory carrier membrane protein 1
affects expression
ISO
tamibarotene affects the expression of SCAMP1 mRNA
CTD
PMID:15498508
NCBI chr 2:25,433,958...25,516,734
Ensembl chr 2:25,433,959...25,516,673
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Sccpdh
saccharopine dehydrogenase (putative)
decreases expression
ISO
tamibarotene results in decreased expression of SCCPDH mRNA
CTD
PMID:15498508
NCBI chr13:91,400,120...91,421,875
Ensembl chr13:91,400,190...91,422,222
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Scd
stearoyl-CoA desaturase
affects expression
ISO
tamibarotene affects the expression of SCD mRNA
CTD
PMID:15498508
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Sec16a
SEC16 homolog A, endoplasmic reticulum export factor
decreases expression
ISO
tamibarotene results in decreased expression of SEC16A mRNA
CTD
PMID:15498508
NCBI chr 3:9,229,687...9,264,837
Ensembl chr 3:9,229,687...9,264,273
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Sec31a
SEC31 homolog A, COPII coat complex component
decreases expression
ISO
tamibarotene results in decreased expression of SEC31A mRNA
CTD
PMID:15498508
NCBI chr14:9,214,324...9,269,281
Ensembl chr14:9,214,349...9,269,273
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Sell
selectin L
increases expression
ISO
tamibarotene results in increased expression of SELL mRNA
CTD
PMID:15498508
NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
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Septin11
septin 11
affects expression decreases expression
ISO
tamibarotene affects the expression of SEPTIN11 mRNA tamibarotene results in decreased expression of SEPTIN11 mRNA
CTD
PMID:15498508
NCBI chr14:14,844,759...14,990,856
Ensembl chr14:14,844,580...14,990,853
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Serbp1
Serpine1 mRNA binding protein 1
affects expression
ISO
tamibarotene affects the expression of SERBP1 mRNA
CTD
PMID:15498508
NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813
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Serinc5
serine incorporator 5
decreases expression
ISO
tamibarotene results in decreased expression of SERINC5 mRNA
CTD
PMID:15498508
NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346
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Serpinb10
serpin family B member 10
decreases expression
ISO
tamibarotene results in decreased expression of SERPINB10 mRNA
CTD
PMID:15498508
NCBI chr13:23,553,348...23,571,182
Ensembl chr13:23,553,430...23,571,182
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Serpinb1a
serpin family B member 1A
increases expression
ISO
tamibarotene results in increased expression of SERPINB1 mRNA
CTD
PMID:15498508
NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
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Serpinb2
serpin family B member 2
decreases expression
ISO
tamibarotene results in decreased expression of SERPINB2 mRNA
CTD
PMID:15498508
NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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Serpinb8
serpin family B member 8
affects expression
ISO
tamibarotene affects the expression of SERPINB8 mRNA
CTD
PMID:15498508
NCBI chr13:23,626,936...23,650,277
Ensembl chr13:23,626,945...23,650,835
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Sfpq
splicing factor proline and glutamine rich
decreases expression
ISO
tamibarotene results in decreased expression of SFPQ mRNA
CTD
PMID:15498508
NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
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Sh2b2
SH2B adaptor protein 2
increases expression
ISO
tamibarotene results in increased expression of SH2B2 mRNA
CTD
PMID:17229644
NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844
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Sh2d1a
SH2 domain containing 1A
decreases expression
ISO
tamibarotene results in decreased expression of SH2D1A mRNA
CTD
PMID:17229644
NCBI chr X:121,373,693...121,401,923
G
Sipa1
signal-induced proliferation-associated 1
increases expression
ISO
tamibarotene results in increased expression of SIPA1 mRNA
CTD
PMID:15498508
NCBI chr 1:202,938,532...202,950,672
Ensembl chr 1:202,938,580...202,950,591
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Skp2
S-phase kinase associated protein 2
decreases expression
ISO
tamibarotene results in decreased expression of SKP2 mRNA
CTD
PMID:15498508
NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
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Sla
src-like adaptor
increases expression
ISO
tamibarotene results in increased expression of SLA mRNA
CTD
PMID:15498508
NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648
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Slc16a1
solute carrier family 16 member 1
affects expression
ISO
tamibarotene affects the expression of SLC16A1 mRNA
CTD
PMID:15498508
NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
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Slc16a3
solute carrier family 16 member 3
increases expression
ISO
tamibarotene results in increased expression of SLC16A3 mRNA
CTD
PMID:15498508
NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562
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Slc16a7
solute carrier family 16 member 7
affects expression
ISO
tamibarotene affects the expression of SLC16A7 mRNA
CTD
PMID:15498508
NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994
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Slc18a3
solute carrier family 18 member A3
increases expression
ISO
tamibarotene results in increased expression of SLC18A3 mRNA
CTD
PMID:20138974
NCBI chr16:7,713,630...7,716,491
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Slc1a1
solute carrier family 1 member 1
increases activity increases expression multiple interactions
EXP
tamibarotene results in increased activity of SLC1A1 protein tamibarotene results in increased expression of SLC1A1 protein HX 630 promotes the reaction [tamibarotene results in increased activity of SLC1A1 protein]; HX 630 promotes the reaction [tamibarotene results in increased expression of SLC1A1 protein]
CTD
PMID:19450544
NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
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Slc1a6
solute carrier family 1 member 6
decreases expression
ISO
tamibarotene results in decreased expression of SLC1A6 mRNA
CTD
PMID:15498508
NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449
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Slc26a2
solute carrier family 26 member 2
affects expression
ISO
tamibarotene affects the expression of SLC26A2 mRNA
CTD
PMID:15498508
NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626
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Slc2a4rg
SLC2A4 regulator
increases expression
ISO
tamibarotene results in increased expression of SLC2A4RG mRNA
CTD
PMID:17229644
NCBI chr 3:168,493,975...168,497,616
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Slc2a5
solute carrier family 2 member 5
increases expression
ISO
tamibarotene results in increased expression of SLC2A5 mRNA
CTD
PMID:15498508
NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
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Slc36a1
solute carrier family 36 member 1
increases expression
ISO
tamibarotene results in increased expression of SLC36A1 mRNA
CTD
PMID:15498508
NCBI chr10:39,319,062...39,357,374
Ensembl chr10:39,324,337...39,354,217
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Slc4a7
solute carrier family 4 member 7
affects expression
ISO
tamibarotene affects the expression of SLC4A7 mRNA
CTD
PMID:15498508
NCBI chr15:10,585,307...10,664,780
Ensembl chr15:10,588,979...10,664,781
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Smad2
SMAD family member 2
decreases expression increases phosphorylation
ISO
tamibarotene results in decreased expression of SMAD2 mRNA tamibarotene results in increased phosphorylation of SMAD2 protein
CTD
PMID:15498508 PMID:17611697
NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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Smad4
SMAD family member 4
decreases expression
ISO
tamibarotene results in decreased expression of SMAD4 mRNA
CTD
PMID:15498508
NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
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Smarcc1
SWI/SNF related BAF chromatin remodeling complex subunit C1
affects expression
ISO
tamibarotene affects the expression of SMARCC1 mRNA
CTD
PMID:15498508
NCBI chr 8:110,111,097...110,214,734
Ensembl chr 8:110,111,122...110,214,720
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Smc4
structural maintenance of chromosomes 4
decreases expression
ISO
tamibarotene results in decreased expression of SMC4 mRNA
CTD
PMID:15498508
NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
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Smc5
structural maintenance of chromosomes 5
affects expression
ISO
tamibarotene affects the expression of SMC5 mRNA
CTD
PMID:15498508
NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096
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Smox
spermine oxidase
increases expression
ISO
tamibarotene results in increased expression of SMOX mRNA
CTD
PMID:15498508
NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710 Ensembl chr X:118,731,900...118,765,710
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Smpd1
sphingomyelin phosphodiesterase 1
increases expression
ISO
tamibarotene results in increased expression of SMPD1 mRNA
CTD
PMID:15498508
NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
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Snrnp200
small nuclear ribonucleoprotein U5 subunit 200
decreases expression
ISO
tamibarotene results in decreased expression of SNRNP200 mRNA
CTD
PMID:15498508
NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182
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Sod3
superoxide dismutase 3
decreases expression
ISO
tamibarotene results in decreased expression of SOD3 mRNA
CTD
PMID:15498508
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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Son
SON DNA and RNA binding protein
affects expression
ISO
tamibarotene affects the expression of SON mRNA
CTD
PMID:15498508
NCBI chr11:30,850,890...30,923,167
Ensembl chr11:30,892,005...30,923,167
G
Spink2
serine peptidase inhibitor, Kazal type 2
decreases expression
ISO
tamibarotene results in decreased expression of SPINK2 mRNA
CTD
PMID:15498508
NCBI chr14:30,967,682...30,974,326
Ensembl chr14:30,967,714...30,974,326
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Spp1
secreted phosphoprotein 1
increases expression
ISO
tamibarotene results in increased expression of SPP1 mRNA
CTD
PMID:15498508
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Sprr2d
small proline-rich protein 2D
affects expression
ISO
tamibarotene affects the expression of SPRR2D mRNA
CTD
PMID:15498508
NCBI chr 2:177,870,082...177,870,679
Ensembl chr 2:177,870,434...177,870,679
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Spry2
sprouty RTK signaling antagonist 2
increases expression
ISO
tamibarotene results in increased expression of SPRY2 mRNA
CTD
PMID:15498508
NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009
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Sri
sorcin
increases expression affects expression
ISO
tamibarotene results in increased expression of SRI mRNA tamibarotene affects the expression of SRI mRNA
CTD
PMID:15498508 PMID:17229644
NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
G
Srsf10
serine and arginine rich splicing factor 10
affects expression decreases expression
ISO
tamibarotene affects the expression of SRSF10 mRNA tamibarotene results in decreased expression of SRSF10 mRNA
CTD
PMID:15498508
NCBI chr 5:148,088,759...148,102,964
Ensembl chr 5:148,088,823...148,101,768
G
Srsf3
serine and arginine rich splicing factor 3
affects expression
ISO
tamibarotene affects the expression of SRSF3 mRNA
CTD
PMID:15498508
NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
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Ss18
SS18 subunit of BAF chromatin remodeling complex
decreases expression
ISO
tamibarotene results in decreased expression of SS18 mRNA
CTD
PMID:15498508
NCBI chr18:5,773,042...5,835,696
Ensembl chr18:5,773,042...5,835,333
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Ssr1
signal sequence receptor subunit 1
affects expression
ISO
tamibarotene affects the expression of SSR1 mRNA
CTD
PMID:15498508
NCBI chr17:26,833,720...26,861,821
Ensembl chr17:26,833,741...26,861,821
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Stat1
signal transducer and activator of transcription 1
increases expression
ISO
tamibarotene results in increased expression of STAT1 mRNA
CTD
PMID:15498508
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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Stat5b
signal transducer and activator of transcription 5B
decreases expression
ISO
tamibarotene results in decreased expression of STAT5B mRNA
CTD
PMID:15498508
NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
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Stx16
syntaxin 16
affects expression
ISO
tamibarotene affects the expression of STX16 mRNA
CTD
PMID:15498508
NCBI chr 3:162,853,764...162,882,489
Ensembl chr 3:162,853,782...162,882,489
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Stx1a
syntaxin 1A
decreases expression
ISO
tamibarotene results in decreased expression of STX1A mRNA
CTD
PMID:15498508
NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
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Surf1
SURF1, cytochrome c oxidase assembly factor
affects expression
ISO
tamibarotene affects the expression of SURF1 mRNA
CTD
PMID:15498508
NCBI chr 3:10,241,793...10,244,686
Ensembl chr 3:10,241,837...10,263,315
G
Sympk
symplekin scaffold protein
affects expression
ISO
tamibarotene affects the expression of SYMPK mRNA
CTD
PMID:15498508
NCBI chr 1:78,672,372...78,700,684
Ensembl chr 1:78,672,378...78,700,684
G
Szrd1
SUZ RNA binding domain containing 1
decreases expression
ISO
tamibarotene results in decreased expression of SZRD1 mRNA
CTD
PMID:15498508
NCBI chr 5:153,418,748...153,443,286
Ensembl chr 5:153,418,748...153,443,252
G
Taf10
TATA-box binding protein associated factor 10
increases expression
ISO
tamibarotene results in increased expression of TAF10 mRNA
CTD
PMID:15498508
NCBI chr 1:160,095,108...160,096,401
Ensembl chr 1:160,095,108...160,096,376
G
Taf15
TATA-box binding protein associated factor 15
decreases expression
ISO
tamibarotene results in decreased expression of TAF15 mRNA
CTD
PMID:15498508
NCBI chr10:68,272,921...68,304,951
Ensembl chr10:68,272,969...68,304,949
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Tagln
transgelin
affects expression
ISO
tamibarotene affects the expression of TAGLN mRNA
CTD
PMID:15498508
NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
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Tap1
transporter 1, ATP binding cassette subfamily B member
increases expression
ISO
tamibarotene results in increased expression of TAP1 mRNA
CTD
PMID:15498508
NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
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Tap2
transporter 2, ATP binding cassette subfamily B member
increases expression
ISO
tamibarotene results in increased expression of TAP2 mRNA
CTD
PMID:15498508
NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
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Tbc1d5
TBC1 domain family, member 5
decreases expression
ISO
tamibarotene results in decreased expression of TBC1D5 mRNA
CTD
PMID:15498508
NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913
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Tbkbp1
TBK1 binding protein 1
decreases expression
ISO
tamibarotene results in decreased expression of TBKBP1 mRNA
CTD
PMID:15498508
NCBI chr10:82,120,558...82,135,749
Ensembl chr10:82,120,564...82,134,352
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Tcirg1
T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3
increases expression
ISO
tamibarotene results in increased expression of TCIRG1 mRNA
CTD
PMID:15498508
NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742
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Tdrd3
tudor domain containing 3
decreases expression
ISO
tamibarotene results in decreased expression of TDRD3 mRNA
CTD
PMID:15498508
NCBI chr15:63,340,531...63,497,208
Ensembl chr15:63,341,235...63,476,110
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Tfdp1
transcription factor Dp-1
affects expression
ISO
tamibarotene affects the expression of TFDP1 mRNA
CTD
PMID:15498508
NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
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Tfdp2
transcription factor Dp-2
decreases expression
ISO
tamibarotene results in decreased expression of TFDP2 mRNA
CTD
PMID:15498508
NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682
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Tfeb
transcription factor EB
increases expression
ISO
tamibarotene results in increased expression of TFEB mRNA
CTD
PMID:17229644
NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
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Tgfb1
transforming growth factor, beta 1
decreases expression multiple interactions
ISO
tamibarotene results in decreased expression of TGFB1 mRNA IL17A affects the reaction [tamibarotene results in decreased expression of TGFB1 mRNA]
CTD
PMID:22077062
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfb2
transforming growth factor, beta 2
increases secretion increases response to substance
ISO
tamibarotene results in increased secretion of TGFB2 protein TGFB2 results in increased susceptibility to tamibarotene
CTD
PMID:17611697
NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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Tgif1
TGFB-induced factor homeobox 1
decreases expression
ISO
tamibarotene results in decreased expression of TGIF1 mRNA
CTD
PMID:15498508
NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
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Tgm2
transglutaminase 2
increases activity
ISO
tamibarotene results in increased activity of TGM2 protein
CTD
PMID:2884032
NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
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Tgm5
transglutaminase 5
increases expression
ISO
tamibarotene results in increased expression of TGM5 mRNA
CTD
PMID:15498508
NCBI chr 3:108,008,087...108,044,013
Ensembl chr 3:108,008,143...108,043,976
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Tgoln2
trans-golgi network protein 2
affects expression
ISO
tamibarotene affects the expression of TGOLN2 mRNA
CTD
PMID:15498508
NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164
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Thbd
thrombomodulin
multiple interactions increases expression
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of THBD mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of THBD mRNA]
CTD
PMID:15020266
NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
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Themis2
thymocyte selection associated family member 2
increases expression
ISO
tamibarotene results in increased expression of THEMIS2 mRNA
CTD
PMID:15498508
NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400
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Timm17a
translocase of inner mitochondrial membrane 17A
affects expression
ISO
tamibarotene affects the expression of TIMM17A mRNA
CTD
PMID:15498508
NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO
tamibarotene results in increased expression of TIMP1 mRNA
CTD
PMID:15498508
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Tm9sf4
transmembrane 9 superfamily member 4
decreases expression
ISO
tamibarotene results in decreased expression of TM9SF4 mRNA
CTD
PMID:15498508
NCBI chr 3:141,627,128...141,675,386
Ensembl chr 3:141,627,346...141,675,386
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Tmbim6
transmembrane BAX inhibitor motif containing 6
affects expression
ISO
tamibarotene affects the expression of TMBIM6 mRNA
CTD
PMID:15498508
NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633
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Tmc6
transmembrane channel like 6
increases expression
ISO
tamibarotene results in increased expression of TMC6 mRNA
CTD
PMID:15498508
NCBI chr10:102,982,059...102,999,509
Ensembl chr10:102,971,229...102,998,960
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Tmpo
thymopoietin
affects expression
ISO
tamibarotene affects the expression of TMPO mRNA
CTD
PMID:15498508
NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
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Tnf
tumor necrosis factor
decreases expression multiple interactions increases expression increases activity
EXP ISO
tamibarotene results in decreased expression of TNF mRNA tamibarotene inhibits the reaction [MBP results in increased expression of TNF mRNA] tamibarotene results in increased expression of TNF mRNA tamibarotene results in increased activity of TNF protein
CTD
PMID:11043609 PMID:11501064 PMID:15498508 PMID:15703382
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip2
TNF alpha induced protein 2
increases expression
ISO
tamibarotene results in increased expression of TNFAIP2 mRNA
CTD
PMID:15498508
NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
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Tnfrsf14
TNF receptor superfamily member 14
increases expression
ISO
tamibarotene results in increased expression of TNFRSF14 mRNA
CTD
PMID:15498508
NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703
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Tnfrsf17
TNF receptor superfamily member 17
increases expression
ISO
tamibarotene results in increased expression of TNFRSF17 mRNA
CTD
PMID:17229644
NCBI chr10:4,301,023...4,306,889
Ensembl chr10:4,301,038...4,306,788
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Tnfsf10
TNF superfamily member 10
increases expression increases activity
ISO
tamibarotene results in increased expression of TNFSF10 mRNA tamibarotene results in increased activity of TNFSF10 protein
CTD
PMID:15498508 PMID:15703382
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Tnfsf14
TNF superfamily member 14
increases expression
ISO
tamibarotene results in increased expression of TNFSF14 mRNA
CTD
PMID:15498508
NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216
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Tnpo1
transportin 1
decreases expression
ISO
tamibarotene results in decreased expression of TNPO1 mRNA
CTD
PMID:15498508
NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
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Top1
DNA topoisomerase I
decreases expression
ISO
tamibarotene results in decreased expression of TOP1 mRNA
CTD
PMID:15498508
NCBI chr 3:149,293,469...149,376,618
Ensembl chr 3:149,293,403...149,376,623
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Top2a
DNA topoisomerase II alpha
affects expression
ISO
tamibarotene affects the expression of TOP2A mRNA
CTD
PMID:15498508
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Top2b
DNA topoisomerase II beta
affects expression
ISO
tamibarotene affects the expression of TOP2B mRNA
CTD
PMID:15498508
NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085
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Tor1b
torsin family 1, member B
increases expression
ISO
tamibarotene results in increased expression of TOR1B mRNA
CTD
PMID:15498508
NCBI chr 3:14,243,181...14,249,279
Ensembl chr 3:14,243,243...14,249,272
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Tpr
translocated promoter region, nuclear basket protein
decreases expression
ISO
tamibarotene results in decreased expression of TPR mRNA
CTD
PMID:15498508
NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
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Traf5
TNF receptor-associated factor 5
decreases expression
ISO
tamibarotene results in decreased expression of TRAF5 mRNA
CTD
PMID:17229644
NCBI chr13:103,569,944...103,618,747
Ensembl chr13:103,572,314...103,618,709
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Trib1
tribbles pseudokinase 1
affects expression
ISO
tamibarotene affects the expression of TRIB1 mRNA
CTD
PMID:15498508
NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
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Trim25
tripartite motif-containing 25
affects expression
ISO
tamibarotene affects the expression of TRIM25 mRNA
CTD
PMID:15498508
NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257
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Trim33
tripartite motif-containing 33
decreases expression
ISO
tamibarotene results in decreased expression of TRIM33 mRNA
CTD
PMID:15498508
NCBI chr 2:190,812,329...190,892,663
Ensembl chr 2:190,807,243...190,888,814
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Trio
trio Rho guanine nucleotide exchange factor
affects expression
ISO
tamibarotene affects the expression of TRIO mRNA
CTD
PMID:15498508
NCBI chr 2:78,505,069...78,801,384
Ensembl chr 2:78,505,070...78,803,135
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Troap
trophinin associated protein
decreases expression
ISO
tamibarotene results in decreased expression of TROAP mRNA
CTD
PMID:15498508
NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365
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Trrap
transformation/transcription domain-associated protein
decreases expression
ISO
tamibarotene results in decreased expression of TRRAP mRNA
CTD
PMID:15498508
NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674
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Tspyl4
TSPY-like 4
decreases expression
ISO
tamibarotene results in decreased expression of TSPYL4 mRNA
CTD
PMID:15498508
NCBI chr20:38,098,756...38,100,752
Ensembl chr20:38,098,677...38,103,053
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Ttc3
tetratricopeptide repeat domain 3
decreases expression
ISO
tamibarotene results in decreased expression of TTC3 mRNA
CTD
PMID:15498508
NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975
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Ttr
transthyretin
increases expression
ISO
tamibarotene results in increased expression of TTR mRNA
CTD
PMID:20138974
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Tuba4a
tubulin, alpha 4A
affects expression
ISO
tamibarotene affects the expression of TUBA4A mRNA
CTD
PMID:15498508
NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
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Tubb2b
tubulin, beta 2B class IIb
increases expression
ISO
tamibarotene results in increased expression of TUBB2B mRNA
CTD
PMID:15498508
NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
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Tubb3
tubulin, beta 3 class III
increases expression
EXP
tamibarotene results in increased expression of TUBB3
CTD
PMID:19182380
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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Tulp3
TUB like protein 3
affects expression
ISO
tamibarotene affects the expression of TULP3 mRNA
CTD
PMID:15498508
NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149
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Twf2
twinfilin actin-binding protein 2
affects expression
ISO
tamibarotene affects the expression of TWF2 mRNA
CTD
PMID:15498508
NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298
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Tyro3
TYRO3 protein tyrosine kinase
decreases expression
ISO
tamibarotene results in decreased expression of TYRO3 mRNA
CTD
PMID:15498508
NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142
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Tyrobp
transmembrane immune signaling adaptor Tyrobp
increases expression
ISO
tamibarotene results in increased expression of TYROBP mRNA
CTD
PMID:15498508
NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
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Uba7
ubiquitin-like modifier activating enzyme 7
increases expression
ISO
tamibarotene results in increased expression of UBA7 mRNA
CTD
PMID:15498508
NCBI chr 8:108,665,289...108,674,097
Ensembl chr 8:108,665,292...108,674,099
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Ugcg
UDP-glucose ceramide glucosyltransferase
affects expression
ISO
tamibarotene affects the expression of UGCG mRNA
CTD
PMID:15498508
NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
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Uros
uroporphyrinogen III synthase
affects expression
ISO
tamibarotene affects the expression of UROS mRNA
CTD
PMID:15498508
NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249
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Usp13
ubiquitin specific peptidase 13
decreases expression
ISO
tamibarotene results in decreased expression of USP13 mRNA
CTD
PMID:15498508
NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222
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Usp9x
ubiquitin specific peptidase 9, X-linked
affects expression
ISO
tamibarotene affects the expression of USP9X mRNA
CTD
PMID:15498508
NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711
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Utp20
UTP20 small subunit processome component
decreases expression
ISO
tamibarotene results in decreased expression of UTP20 mRNA
CTD
PMID:15498508
NCBI chr 7:23,134,630...23,215,639
Ensembl chr 7:23,134,637...23,215,632
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Vasp
vasodilator-stimulated phosphoprotein
increases expression
ISO
tamibarotene results in increased expression of VASP mRNA
CTD
PMID:15498508
NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
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Vav1
vav guanine nucleotide exchange factor 1
increases expression
ISO
tamibarotene results in increased expression of VAV1 mRNA
CTD
PMID:17229644
NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937
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Vav3
vav guanine nucleotide exchange factor 3
decreases expression
ISO
tamibarotene results in decreased expression of VAV3 mRNA
CTD
PMID:17229644
NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321
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Vegfa
vascular endothelial growth factor A
increases secretion increases expression
ISO
tamibarotene results in increased secretion of VEGFA protein tamibarotene results in increased expression of VEGFA mRNA
CTD
PMID:17170094
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vezf1
vascular endothelial zinc finger 1
affects expression
ISO
tamibarotene affects the expression of VEZF1 mRNA
CTD
PMID:15498508
NCBI chr10:72,859,669...72,876,111
Ensembl chr10:72,859,877...72,876,111
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Vim
vimentin
decreases expression
ISO
tamibarotene results in decreased expression of VIM mRNA
CTD
PMID:15498508
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Vrk2
VRK serine/threonine kinase 2
affects expression
ISO
tamibarotene affects the expression of VRK2 mRNA
CTD
PMID:15498508
NCBI chr14:100,313,771...100,434,520
Ensembl chr14:100,313,601...100,434,527
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Wars1
tryptophanyl-tRNA synthetase 1
increases expression
ISO
tamibarotene results in increased expression of WARS1 mRNA
CTD
PMID:15498508
NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
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Wee1
WEE1 G2 checkpoint kinase
affects expression
ISO
tamibarotene affects the expression of WEE1 mRNA
CTD
PMID:15498508
NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
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Wnk1
WNK lysine deficient protein kinase 1
decreases expression
ISO
tamibarotene results in decreased expression of WNK1 mRNA
CTD
PMID:15498508
NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
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Xbp1
X-box binding protein 1
increases expression
ISO
tamibarotene results in increased expression of XBP1 mRNA
CTD
PMID:17229644
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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Xpot
exportin for tRNA
decreases expression
ISO
tamibarotene results in decreased expression of XPOT mRNA
CTD
PMID:15498508
NCBI chr 7:57,111,536...57,152,013
Ensembl chr 7:57,111,536...57,152,099
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Ykt6
YKT6 v-SNARE homolog
affects expression
ISO
tamibarotene affects the expression of YKT6 mRNA
CTD
PMID:15498508
NCBI chr14:80,832,187...80,843,394
Ensembl chr14:80,832,187...80,843,385
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
affects expression
ISO
tamibarotene affects the expression of YWHAZ mRNA
CTD
PMID:15498508
NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
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Zbtb16
zinc finger and BTB domain containing 16
decreases expression
ISO
tamibarotene results in decreased expression of ZBTB16 mRNA
CTD
PMID:15498508
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
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Zcchc24
zinc finger CCHC-type containing 24
increases expression
ISO
tamibarotene results in increased expression of ZCCHC24 mRNA
CTD
PMID:15498508
NCBI chr16:1,274,544...1,326,664
Ensembl chr16:1,274,548...1,326,696
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Zfp148
zinc finger protein 148
affects expression decreases expression
ISO
tamibarotene affects the expression of ZNF148 mRNA tamibarotene results in decreased expression of ZNF148 mRNA
CTD
PMID:15498508
NCBI chr11:67,276,455...67,385,803
Ensembl chr11:67,281,707...67,385,772
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Zfp263
zinc finger protein 263
decreases expression
ISO
tamibarotene results in decreased expression of ZNF263 mRNA
CTD
PMID:15498508
NCBI chr10:11,764,424...11,774,324
Ensembl chr10:11,764,427...11,771,235
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Zfp267
zinc finger protein 267
decreases expression
ISO
tamibarotene results in decreased expression of ZNF267 mRNA
CTD
PMID:15498508
NCBI chr 2:119,017,280...119,035,885
Ensembl chr 2:119,017,285...119,031,900
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