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ONTOLOGY REPORT - ANNOTATIONS


Term:sulpiride
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Accession:CHEBI:32168 term browser browse the term
Definition:A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Synonyms:exact_synonym: N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
 related_synonym: 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide;   Formula=C15H23N3O4S;   InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21);   InChIKey=BGRJTUBHPOOWDU-UHFFFAOYSA-N;   N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide;   N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide;   SMILES=CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O;   Sulpirid;   Sulpyrid;   sulpirida;   sulpiridum
 xref: CAS:15676-16-1 "ChemIDplus";   CAS:15676-16-1 "KEGG DRUG";   CAS:15676-16-1 "NIST Chemistry WebBook";   DrugBank:DB00391;   Drug_Central:2537 "DrugCentral";   KEGG:D01226;   LINCS:LSM-5080
 xref_mesh: MESH:D013469
 xref: PMID:16327907 "Europe PMC";   PMID:16924461 "Europe PMC";   PMID:17912501 "Europe PMC";   PMID:17942035 "Europe PMC";   PMID:18757738 "Europe PMC";   PMID:18985321 "Europe PMC";   PMID:19370694 "Europe PMC";   PMID:19546258 "Europe PMC";   PMID:19672580 "Europe PMC";   PMID:19864199 "Europe PMC";   PMID:19941957 "Europe PMC";   PMID:20061345 "Europe PMC";   PMID:20091661 "Europe PMC";   PMID:20177884 "Europe PMC";   PMID:20304506 "Europe PMC";   PMID:20305607 "Europe PMC";   PMID:20538381 "Europe PMC";   PMID:20599913 "Europe PMC";   PMID:20875676 "Europe PMC";   Patent:DE2903891;   Patent:US3342826;   Reaxys:494008 "Reaxys";   Wikipedia:Sulpiride


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sulpiride term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Adcy5 adenylate cyclase 5 JBrowse link 11 68,695,839 68,842,452 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Ahrr aryl-hydrocarbon receptor repressor JBrowse link 1 31,603,297 31,698,329 RGD:6480464
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Arnt aryl hydrocarbon receptor nuclear translocator JBrowse link 2 196,594,178 196,651,486 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:6480464
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:6480464
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cckbr cholecystokinin B receptor JBrowse link 1 170,262,218 170,272,298 RGD:6480464
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6480464
G Cish cytokine inducible SH2-containing protein JBrowse link 8 116,054,547 116,059,494 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:6480464
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:6480464
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:6480464
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480464
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:6480464
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:6480464
G Kcnh1 potassium voltage-gated channel subfamily H member 1 JBrowse link 13 110,920,712 111,232,291 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 JBrowse link 13 53,750,470 53,870,288 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:6480464
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:6480464
G Scarb1 scavenger receptor class B, member 1 JBrowse link 12 36,694,952 36,761,445 RGD:6480464
G Slc18a2 solute carrier family 18 member A2 JBrowse link 1 280,397,831 280,457,968 RGD:6480464
G Slc22a23 solute carrier family 22, member 23 JBrowse link 17 31,236,015 31,403,685 RGD:6480464
G Slc22a3 solute carrier family 22 member 3 JBrowse link 1 48,433,079 48,521,261 RGD:6480464
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:6480464
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:6480464
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:6480464
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:6480464
G Srd5a2 steroid 5 alpha-reductase 2 JBrowse link 6 25,279,635 25,315,501 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            antiemetic 5083
              sulpiride 47
                (R)-(+)-sulpiride 0
                (S)-(-)-sulpiride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                monocarboxylic acid amide 13180
                                                  arenecarboxamide 6406
                                                    benzamides 6406
                                                      sulpiride 47
                                                        (R)-(+)-sulpiride 0
                                                        (S)-(-)-sulpiride 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.