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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sucralose
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Accession:CHEBI:32159 term browser browse the term
Definition:A disaccharide derivative consisting of 4-chloro-4-deoxy-alpha-D-galactopyranose and 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose units linked by a glycosidic bond.
Synonyms:exact_synonym: 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-alpha-D-galactopyranoside
 related_synonym: Formula=C12H19Cl3O8;   InChI=1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1;   InChIKey=BAQAVOSOZGMPRM-QBMZZYIRSA-N;   SMILES=OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl;   Trichlorosucrose
 xref: CAS:56038-13-2;   HMDB:HMDB0031554;   KEGG:C12285
 xref_mesh: MESH:C026285
 xref: PMID:24687789;   PMID:25236212;   Reaxys:3654410;   Wikipedia:Sucralose


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sucralose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gast gastrin increases secretion EXP trichlorosucrose results in increased secretion of GAST protein CTD PMID:19208342 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Tas1r2 taste 1 receptor member 2 multiple interactions
affects binding
ISO trichlorosucrose results in increased activity of [TAS1R2 protein binds to TAS1R3 protein]
trichlorosucrose binds to TAS1R2 protein
CTD PMID:20173092 PMID:20302879 NCBI chr 5:158,119,894...158,135,733
Ensembl chr 5:158,042,587...158,135,733
JBrowse link
G Tas1r3 taste 1 receptor member 3 multiple interactions
affects binding
ISO trichlorosucrose results in increased activity of [TAS1R2 protein binds to TAS1R3 protein]
trichlorosucrose binds to TAS1R3 protein
CTD PMID:20173092 PMID:20302879 NCBI chr 5:173,307,325...173,312,950
Ensembl chr 5:173,308,870...173,312,023
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      biological role 19720
        xenobiotic 18393
          sucralose 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            heteroorganic entity 19206
                              organochalcogen compound 18951
                                organooxygen compound 18877
                                  carbohydrates and carbohydrate derivatives 12259
                                    carbohydrate 12259
                                      oligosaccharide 554
                                        disaccharide 460
                                          disaccharide derivative 419
                                            sucralose 3
paths to the root