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ONTOLOGY REPORT - ANNOTATIONS


Term:bupivacaine
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Accession:CHEBI:3215 term browser browse the term
Definition:A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Synonyms:exact_synonym: rac-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
 related_synonym: (RS)-bupivacaine;   1-Butyl-2',6'-pipecoloxylidide;   1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide;   Carbostesin;   DL-Bupivacaine;   Formula=C18H28N2O;   bupivacaina;   bupivacainum;   dl-1-Butyl-2',6'-pipecoloxylidide;   racemic bupivacaine
 alt_id: CHEBI:250882
 xref: CAS:2180-92-9 "KEGG COMPOUND";   CAS:2180-92-9 "NIST Chemistry WebBook";   CAS:38396-39-3 "ChemIDplus";   CAS:38396-39-3 "KEGG COMPOUND";   DrugBank:DB00297;   HMDB:HMDB0014442;   KEGG:C07529;   KEGG:D07552
 xref_mesh: MESH:D002045
 xref: PMID:10211016 "Europe PMC";   PMID:10499757 "Europe PMC";   PMID:11018648 "Europe PMC";   PMID:11020763 "Europe PMC";   PMID:11412729 "Europe PMC";   PMID:11529341 "Europe PMC";   PMID:11759364 "Europe PMC";   PMID:11778087 "Europe PMC";   PMID:11801199 "Europe PMC";   PMID:11812691 "Europe PMC";   PMID:14980918 "Europe PMC";   PMID:15321223 "Europe PMC";   PMID:16037174 "Europe PMC";   PMID:16418020 "Europe PMC";   PMID:17134470 "Europe PMC";   PMID:18299091 "Europe PMC";   PMID:18420860 "Europe PMC";   PMID:18451389 "Europe PMC";   PMID:18940244 "Europe PMC";   PMID:19468619 "Europe PMC";   PMID:19800297 "Europe PMC";   PMID:20164497 "Europe PMC";   PMID:23446090 "Europe PMC";   PMID:23807278 "Europe PMC";   PMID:23925646 "Europe PMC";   PMID:23978626 "Europe PMC";   PMID:24117122 "Europe PMC";   PMID:24117225 "Europe PMC";   PMID:24200700 "Europe PMC";   PMID:24317184 "Europe PMC";   PMID:24393760 "Europe PMC";   PMID:24398818 "Europe PMC";   PMID:24445889 "Europe PMC";   PMID:24450503 "Europe PMC";   PMID:24476569 "Europe PMC";   PMID:24513957 "Europe PMC";   PMID:24532522 "Europe PMC";   PMID:24535791 "Europe PMC";   PMID:8368547 "Europe PMC";   PMID:8489063 "Europe PMC";   PMID:9209608 "Europe PMC";   PMID:9989796 "Europe PMC";   Patent:US2955111;   Reaxys:280794 "Reaxys";   Wikipedia:Bupivacaine
 cyclic_relationship: is_conjugate_base_of CHEBI:77455


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bupivacaine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 JBrowse link 15 51,222,954 51,250,787 RGD:6480464
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 4 95,945,356 95,970,666 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:6480464
G Kcnk9 potassium two pore domain channel subfamily K member 9 JBrowse link 7 113,894,918 113,938,397 RGD:6480464
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:6480464
G Myf5 myogenic factor 5 JBrowse link 7 49,729,533 49,732,974 RGD:6480464
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:6480464
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:6480464
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:6480464
G Ptgdr prostaglandin D2 receptor JBrowse link 15 19,195,606 19,196,508 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Slc6a2 solute carrier family 6 member 2 JBrowse link 19 15,391,682 15,431,274 RGD:6480464
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      chemical substance 10725
        mixture 9929
          racemate 8658
            bupivacaine 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                monocarboxylic acid amide 13180
                                                  piperidinecarboxamide 26
                                                    1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide 18
                                                      dextrobupivacaine 18
                                                        bupivacaine 18
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.