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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Ramatroban
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Accession:CHEBI:32087 term browser browse the term
Synonyms:related_synonym: Formula=C21H21FN2O4S;   InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1;   InChIKey=LDXDSHIEDAPSSA-OAHLLOKOSA-N;   SMILES=C(CC(O)=O)N1C2=C(C=3C1=CC=CC3)C[C@@H](CC2)NS(=O)(=O)C4=CC=C(C=C4)F;   baynas
 xref: CAS:116649-85-5;   Drug_Central:2354;   KEGG:D01128
 xref_mesh: MESH:C063119


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Ramatroban term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions
affects binding
ISO
EXP
ramatroban binds to and affects the activity of PTGDR2 protein; ramatroban binds to and results in decreased activity of PTGDR2 protein; ramatroban inhibits the reaction [13,14-dihydro-15-ketoprostaglandin D2 binds to and results in increased activity of PTGDR2 protein]; ramatroban inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 binds to and results in increased activity of PTGDR2 protein]; ramatroban inhibits the reaction [15R-methyl prostaglandin D2 binds to and results in increased activity of PTGDR2 protein]; ramatroban inhibits the reaction [Indomethacin binds to and results in increased activity of PTGDR2 protein]; ramatroban inhibits the reaction [Prostaglandin D2 binds to and results in increased activity of PTGDR2 protein]
ramatroban binds to PTGDR2 protein
ramatroban inhibits the reaction [Prostaglandin D2 binds to PTGDR2 protein]
CTD PMID:15528449, PMID:15563582, PMID:16256979, PMID:21916510 NCBI chr 1:226,976,455...226,995,641
Ensembl chr 1:226,993,250...226,994,849
JBrowse link
G Tbxa2r thromboxane A2 receptor multiple interactions EXP ramatroban binds to and results in decreased activity of TBXA2R protein CTD PMID:16979129 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Ramatroban 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Ramatroban 2
paths to the root

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