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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:propylparaben
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Accession:CHEBI:32063 term browser browse the term
Definition:The benzoate ester that is the propyl ester of 4-hydroxybenzoic acid. Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products. Also used as a food additive.
Synonyms:related_synonym: 4-Hydroxybenzoic acid propyl ester;   Formula=C10H12O3;   InChI=1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3;   InChIKey=QELSKZZBTMNZEB-UHFFFAOYSA-N;   Propyl 4-hydroxybenzoate;   Propyl p-hydroxybenzoate;   Propyl parahydroxybenzoate;   SMILES=CCCOC(=O)c1ccc(O)cc1;   n-Propyl 4-hydroxybenzoate;   n-Propyl p-hydroxybenzoate;   n-propyl paraben;   p-Hydroxybenzoic acid propyl ester;   p-Hydroxybenzoic propyl ester;   p-Hydroxypropyl benzoate;   p-Oxybenzoesaeurepropylester;   propyl paraben
 xref: CAS:94-13-3;   Drug_Central:2307;   HMDB:HMDB0032574;   KEGG:D01422
 xref_mesh: MESH:C006068
 xref: PMID:21492176;   PMID:21549034;   PMID:21608130;   PMID:21645663;   PMID:21705745;   PMID:21886901;   PMID:22165009;   PMID:22177019;   PMID:22220814;   PMID:22237600;   PMID:22249112;   PMID:22305363;   PMID:22337803;   Reaxys:1103245;   Wikipedia:Propylparaben


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propylparaben term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO propylparaben results in increased expression of ADIPOQ mRNA CTD PMID:22956630 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO propylparaben results in increased expression of APAF1 mRNA CTD PMID:24481588 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Ar androgen receptor affects binding EXP propylparaben binds to AR protein CTD PMID:14565775, PMID:20371976 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Areg amphiregulin increases expression ISO propylparaben results in increased expression of AREG mRNA CTD PMID:31939680 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Atm ATM serine/threonine kinase affects expression ISO propylparaben affects the expression of ATM mRNA CTD PMID:24481588 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atr ATR serine/threonine kinase increases expression ISO propylparaben results in increased expression of ATR mRNA CTD PMID:24481588 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO propylparaben results in increased expression of BAD mRNA CTD PMID:24481588 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO propylparaben results in increased expression of BAK1 mRNA CTD PMID:24481588 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO propylparaben results in increased expression of BAX mRNA CTD PMID:24481588, PMID:31306770 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO propylparaben results in increased expression of BBC3 mRNA CTD PMID:24481588 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO propylparaben results in increased expression of BCL2 mRNA CTD PMID:24481588 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO propylparaben results in increased expression of BCL2L1 mRNA; propylparaben results in increased expression of BCL2L1 protein CTD PMID:24481588 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO propylparaben results in increased expression of BCL2L11 mRNA CTD PMID:24481588 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bcl2l2 Bcl2-like 2 increases expression ISO propylparaben results in increased expression of BCL2L2 mRNA CTD PMID:24481588 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO propylparaben results in increased expression of BID mRNA CTD PMID:24481588 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bik BCL2-interacting killer increases expression ISO propylparaben results in increased expression of BIK mRNA CTD PMID:24481588 NCBI chr 7:124,390,924...124,410,449
Ensembl chr 7:124,391,432...124,410,447
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO propylparaben results in increased expression of BIRC5 mRNA CTD PMID:24481588 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 increases expression ISO propylparaben results in increased expression of BIRC6 mRNA CTD PMID:24481588 NCBI chr 6:21,900,763...22,092,484
Ensembl chr 6:21,950,100...22,092,346
JBrowse link
G Bok BCL2 family apoptosis regulator BOK increases expression ISO propylparaben results in increased expression of BOK mRNA CTD PMID:24481588 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Casp1 caspase 1 increases expression ISO propylparaben results in increased expression of CASP1 mRNA CTD PMID:24481588 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp2 caspase 2 increases expression ISO propylparaben results in increased expression of CASP2 mRNA CTD PMID:24481588 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 increases expression ISO propylparaben results in increased expression of CASP3 mRNA CTD PMID:24481588 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 increases expression ISO propylparaben results in increased expression of CASP4 mRNA CTD PMID:24481588 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp6 caspase 6 increases expression ISO propylparaben results in increased expression of CASP6 mRNA CTD PMID:24481588 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 increases expression ISO propylparaben results in increased expression of CASP7 mRNA CTD PMID:24481588 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases expression ISO propylparaben results in increased expression of CASP8 mRNA; propylparaben results in increased expression of CASP8 protein CTD PMID:24481588 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 increases expression ISO propylparaben results in increased expression of CASP8AP2 mRNA CTD PMID:24481588 NCBI chr 5:47,853,699...47,891,147
Ensembl chr 5:47,853,818...47,891,668
JBrowse link
G Casp9 caspase 9 increases expression ISO propylparaben results in increased expression of CASP9 mRNA; propylparaben results in increased expression of CASP9 protein CTD PMID:24481588 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccna1 cyclin A1 increases expression ISO propylparaben results in increased expression of CCNA1 mRNA CTD PMID:24481588 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccna2 cyclin A2 increases expression ISO propylparaben results in increased expression of CCNA2 mRNA CTD PMID:24481588 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO propylparaben results in decreased expression of CCNB1 mRNA CTD PMID:24481588 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO propylparaben results in increased expression of CCND1 mRNA CTD PMID:24481588 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 increases expression ISO propylparaben results in increased expression of CCNE1 mRNA CTD PMID:24481588 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdc25a cell division cycle 25A increases expression ISO propylparaben results in increased expression of CDC25A mRNA CTD PMID:24481588 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression ISO propylparaben results in increased expression of CDK2 mRNA CTD PMID:24481588 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO propylparaben results in increased expression of CDK4 mRNA CTD PMID:24481588, PMID:31306770 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO propylparaben results in decreased expression of CDK6 mRNA CTD PMID:24481588 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
increases expression
ISO propylparaben results in decreased expression of CDKN1A mRNA; propylparaben results in decreased expression of CDKN1A protein
propylparaben results in increased expression of CDKN1A mRNA
CTD PMID:24481588, PMID:31306770 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO propylparaben results in increased expression of CEBPA mRNA CTD PMID:22956630 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 affects expression ISO propylparaben affects the expression of CYP19A1 mRNA; propylparaben affects the expression of CYP19A1 protein CTD PMID:23744433 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity EXP propylparaben results in decreased activity of CYP1A1 protein CTD PMID:27432241 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity EXP propylparaben results in decreased activity of CYP1A2 protein CTD PMID:27432241 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP propylparaben results in decreased activity of CYP2B1 protein CTD PMID:27432241 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity EXP propylparaben results in decreased activity of CYP2C11 protein CTD PMID:27432241 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity EXP propylparaben results in decreased activity of CYP2E1 protein CTD PMID:27432241 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 decreases activity EXP propylparaben results in decreased activity of CYP3A62 protein CTD PMID:27432241 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression ISO propylparaben results in increased expression of DIABLO mRNA CTD PMID:24481588 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO propylparaben results in increased expression of E2F1 mRNA CTD PMID:24481588 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G E2f3 E2F transcription factor 3 affects expression ISO propylparaben affects the expression of E2F3 mRNA CTD PMID:24481588 NCBI chr17:36,334,136...36,408,831
Ensembl chr17:36,334,147...36,408,831
JBrowse link
G Esr1 estrogen receptor 1 affects binding
increases expression
increases activity
multiple interactions
EXP
ISO
propylparaben binds to ESR1 protein
propylparaben results in increased expression of ESR1 mRNA; propylparaben results in increased expression of ESR1 protein
propylparaben results in increased activity of ESR1 protein
fulvestrant inhibits the reaction [propylparaben results in increased activity of ESR1 protein]; propylparaben binds to and results in increased activity of ESR1 protein
CTD PMID:11193391, PMID:19063592, PMID:20132880, PMID:22562034, PMID:23567241, PMID:25128701 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 affects binding
increases expression
multiple interactions
EXP
ISO
propylparaben binds to ESR2 protein
propylparaben results in increased expression of ESR2 mRNA; propylparaben results in increased expression of ESR2 protein
propylparaben binds to and results in increased activity of ESR2 protein
CTD PMID:11193391, PMID:20132880, PMID:23567241, PMID:25128701 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO propylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436
JBrowse link
G Faah fatty acid amide hydrolase decreases activity ISO propylparaben results in decreased activity of FAAH protein CTD PMID:27659731 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO propylparaben results in increased expression of FABP4 mRNA CTD PMID:22956630, PMID:24155963 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fadd Fas associated via death domain increases expression ISO propylparaben results in increased expression of FADD mRNA CTD PMID:24481588 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fasn fatty acid synthase increases expression ISO propylparaben results in increased expression of FASN mRNA CTD PMID:22956630 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Flg filaggrin multiple interactions ISO FLG gene mutant form affects the abundance of and affects the susceptibility to propylparaben CTD PMID:28525834 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression ISO propylparaben results in increased expression of GPER1 mRNA; propylparaben results in increased expression of GPER1 protein CTD PMID:26253279 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G H2ax H2A.X variant histone increases expression
multiple interactions
ISO propylparaben results in increased expression of H2AX protein modified form
Fulvestrant inhibits the reaction [propylparaben results in increased expression of H2AX protein modified form]
CTD PMID:31939680 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Lep leptin decreases expression
increases expression
ISO propylparaben results in decreased expression of LEP mRNA
propylparaben results in increased expression of LEP mRNA
CTD PMID:22956630 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation ISO propylparaben affects the phosphorylation of MAPK1 protein CTD PMID:26253279 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation ISO propylparaben affects the phosphorylation of MAPK3 protein CTD PMID:26253279 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO propylparaben results in increased expression of MCL1 mRNA CTD PMID:24481588 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
ISO NRG1 protein promotes the reaction [propylparaben results in increased expression of MYC mRNA]; propylparaben promotes the reaction [NRG1 protein results in increased expression of MYC mRNA] CTD PMID:26502914 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO propylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression EXP propylparaben results in increased expression of NR1I2 mRNA CTD PMID:31472229 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO propylparaben results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases activity
ISO [butylparaben co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with propylparaben] results in increased activity of NR3C1 protein; [tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein
propylparaben results in increased activity of NR3C1 protein
CTD PMID:25448277 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO NRG1 protein promotes the reaction [propylparaben results in increased expression of MYC mRNA]; propylparaben promotes the reaction [NRG1 protein results in increased expression of MYC mRNA] CTD PMID:26502914 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Pgr progesterone receptor increases expression ISO propylparaben results in increased expression of PGR mRNA CTD PMID:25128701, PMID:31939680 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects expression EXP propylparaben affects the expression of PPARA mRNA CTD PMID:31472229 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
ISO propylparaben results in increased expression of PPARG mRNA
PPARG protein promotes the reaction [propylparaben binds to and results in increased activity of PPARG protein]
CTD PMID:22956630, PMID:24155963 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases expression ISO propylparaben results in increased expression of RIPK1 mRNA CTD PMID:24481588 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 increases expression ISO propylparaben results in increased expression of RIPK2 mRNA CTD PMID:24481588 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
JBrowse link
G S100g S100 calcium binding protein G increases expression EXP propylparaben results in increased expression of S100G protein CTD PMID:19654335 NCBI chr  X:33,442,820...33,445,714
Ensembl chr  X:33,443,186...33,445,709
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO propylparaben binds to SHBG protein CTD PMID:25349334 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Star steroidogenic acute regulatory protein increases expression ISO propylparaben results in increased expression of STAR mRNA CTD PMID:31306770 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [propylparaben results in increased expression of TFF1 mRNA] CTD PMID:16797915, PMID:22562034 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tnf tumor necrosis factor increases expression ISO propylparaben results in increased expression of TNF mRNA CTD PMID:24481588 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO propylparaben results in increased expression of TNFRSF10A mRNA CTD PMID:24481588 NCBI chr15:51,433,853...51,464,215 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO propylparaben results in increased expression of TNFRSF1A mRNA CTD PMID:24481588 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO propylparaben results in increased expression of TNFRSF25 mRNA CTD PMID:24481588 NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO propylparaben results in increased expression of TNFSF10 mRNA CTD PMID:24481588 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tp53 tumor protein p53 increases expression ISO propylparaben results in increased expression of TP53 mRNA; propylparaben results in increased expression of TP53 protein CTD PMID:24481588 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 increases expression ISO propylparaben results in increased expression of TP53BP1 protein CTD PMID:31939680 NCBI chr 3:113,160,030...113,259,701
Ensembl chr 3:113,160,000...113,231,790
JBrowse link
G Tradd TNFRSF1A-associated via death domain increases expression ISO propylparaben results in increased expression of TRADD mRNA CTD PMID:24481588 NCBI chr19:37,214,461...37,221,099
Ensembl chr19:37,214,471...37,216,572
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        antimicrobial agent 17309
          propylparaben 86
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        aromatic carboxylic acid 10889
                                          benzoic acids 10858
                                            benzoic acid 3839
                                              hydroxybenzoic acid 3227
                                                monohydroxybenzoic acid 1264
                                                  4-hydroxybenzoic acid 619
                                                    4-hydroxybenzoate ester 614
                                                      paraben 614
                                                        propylparaben 86
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.