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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:propylparaben
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Accession:CHEBI:32063 term browser browse the term
Definition:The benzoate ester that is the propyl ester of 4-hydroxybenzoic acid. Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products. Also used as a food additive.
Synonyms:exact_synonym: propyl 4-hydroxybenzoate
 related_synonym: 4-Hydroxybenzoic acid propyl ester;   Formula=C10H12O3;   InChI=1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3;   InChIKey=QELSKZZBTMNZEB-UHFFFAOYSA-N;   Propyl p-hydroxybenzoate;   Propyl parahydroxybenzoate;   SMILES=CCCOC(=O)c1ccc(O)cc1;   n-Propyl 4-hydroxybenzoate;   n-Propyl p-hydroxybenzoate;   n-propyl paraben;   p-Hydroxybenzoic acid propyl ester;   p-Hydroxybenzoic propyl ester;   p-Hydroxypropyl benzoate;   p-Oxybenzoesaeurepropylester;   propyl paraben
 xref: CAS:94-13-3;   Drug_Central:2307;   HMDB:HMDB0032574;   KEGG:D01422
 xref_mesh: MESH:C006068
 xref: PMID:21492176;   PMID:21549034;   PMID:21608130;   PMID:21645663;   PMID:21705745;   PMID:21886901;   PMID:22165009;   PMID:22177019;   PMID:22220814;   PMID:22237600;   PMID:22249112;   PMID:22305363;   PMID:22337803;   Reaxys:1103245;   Wikipedia:Propylparaben


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propylparaben term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO propylparaben results in increased expression of ADIPOQ mRNA CTD PMID:22956630 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO propylparaben results in increased expression of APAF1 mRNA CTD PMID:24481588 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Ar androgen receptor affects binding
multiple interactions
EXP
ISO
propylparaben binds to AR protein
propylparaben inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]
CTD PMID:14565775 PMID:20371976 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Areg amphiregulin increases expression ISO propylparaben results in increased expression of AREG mRNA CTD PMID:31939680 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Atm ATM serine/threonine kinase affects expression ISO propylparaben affects the expression of ATM mRNA CTD PMID:24481588 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atr ATR serine/threonine kinase increases expression ISO propylparaben results in increased expression of ATR mRNA CTD PMID:24481588 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
decreases expression
ISO propylparaben results in increased expression of BAD mRNA
propylparaben results in decreased expression of BAD mRNA
CTD PMID:24481588 PMID:33358972 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO propylparaben results in increased expression of BAK1 mRNA CTD PMID:24481588 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO propylparaben results in increased expression of BAX mRNA CTD PMID:24481588 PMID:31306770 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO propylparaben results in increased expression of BBC3 mRNA CTD PMID:24481588 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
ISO propylparaben results in increased expression of BCL2 mRNA
propylparaben results in decreased expression of BCL2 mRNA
CTD PMID:24481588 PMID:33358972 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO propylparaben results in increased expression of BCL2L1 mRNA; propylparaben results in increased expression of BCL2L1 protein CTD PMID:24481588 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO propylparaben results in increased expression of BCL2L11 mRNA CTD PMID:24481588 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l2 Bcl2-like 2 increases expression ISO propylparaben results in increased expression of BCL2L2 mRNA CTD PMID:24481588 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO propylparaben results in increased expression of BID mRNA CTD PMID:24481588 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bik BCL2-interacting killer increases expression ISO propylparaben results in increased expression of BIK mRNA CTD PMID:24481588 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO propylparaben results in increased expression of BIRC5 mRNA CTD PMID:24481588 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 increases expression ISO propylparaben results in increased expression of BIRC6 mRNA CTD PMID:24481588 NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434
JBrowse link
G Bok BCL2 family apoptosis regulator BOK increases expression ISO propylparaben results in increased expression of BOK mRNA CTD PMID:24481588 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Casp1 caspase 1 increases expression ISO propylparaben results in increased expression of CASP1 mRNA CTD PMID:24481588 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp2 caspase 2 increases expression ISO propylparaben results in increased expression of CASP2 mRNA CTD PMID:24481588 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases expression ISO propylparaben results in increased expression of CASP3 mRNA CTD PMID:24481588 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression ISO propylparaben results in increased expression of CASP4 mRNA CTD PMID:24481588 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 increases expression ISO propylparaben results in increased expression of CASP6 mRNA CTD PMID:24481588 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 increases expression ISO propylparaben results in increased expression of CASP7 mRNA CTD PMID:24481588 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases expression ISO propylparaben results in increased expression of CASP8 mRNA; propylparaben results in increased expression of CASP8 protein CTD PMID:24481588 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 increases expression ISO propylparaben results in increased expression of CASP8AP2 mRNA CTD PMID:24481588 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
JBrowse link
G Casp9 caspase 9 increases expression ISO propylparaben results in increased expression of CASP9 mRNA; propylparaben results in increased expression of CASP9 protein CTD PMID:24481588 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccna1 cyclin A1 increases expression ISO propylparaben results in increased expression of CCNA1 mRNA CTD PMID:24481588 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccna2 cyclin A2 increases expression
decreases expression
ISO propylparaben results in increased expression of CCNA2 mRNA
propylparaben results in decreased expression of CCNA2 mRNA
CTD PMID:24481588 PMID:33358972 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO propylparaben results in decreased expression of CCNB1 mRNA CTD PMID:24481588 PMID:33358972 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO propylparaben results in increased expression of CCND1 mRNA CTD PMID:24481588 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 increases expression
decreases expression
ISO propylparaben results in increased expression of CCNE1 mRNA
propylparaben results in decreased expression of CCNE1 mRNA
CTD PMID:24481588 PMID:33358972 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdc25a cell division cycle 25A increases expression ISO propylparaben results in increased expression of CDC25A mRNA CTD PMID:24481588 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression
decreases expression
ISO propylparaben results in increased expression of CDK2 mRNA
propylparaben results in decreased expression of CDK2 mRNA
CTD PMID:24481588 PMID:33358972 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO propylparaben results in increased expression of CDK4 mRNA CTD PMID:24481588 PMID:31306770 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO propylparaben results in decreased expression of CDK6 mRNA CTD PMID:24481588 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
increases expression
ISO propylparaben results in decreased expression of CDKN1A mRNA; propylparaben results in decreased expression of CDKN1A protein
propylparaben results in increased expression of CDKN1A mRNA
CTD PMID:24481588 PMID:31306770 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO propylparaben results in increased expression of CEBPA mRNA CTD PMID:22956630 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 affects expression ISO propylparaben affects the expression of CYP19A1 mRNA; propylparaben affects the expression of CYP19A1 protein CTD PMID:23744433 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity EXP propylparaben results in decreased activity of CYP1A1 protein CTD PMID:27432241 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity EXP propylparaben results in decreased activity of CYP1A2 protein CTD PMID:27432241 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP propylparaben results in decreased activity of CYP2B1 protein CTD PMID:27432241 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity EXP propylparaben results in decreased activity of CYP2C11 protein CTD PMID:27432241 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity EXP propylparaben results in decreased activity of CYP2E1 protein CTD PMID:27432241 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 decreases activity EXP propylparaben results in decreased activity of CYP3A62 protein CTD PMID:27432241 NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression ISO propylparaben results in increased expression of DIABLO mRNA CTD PMID:24481588 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO propylparaben results in increased expression of E2F1 mRNA CTD PMID:24481588 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E2f3 E2F transcription factor 3 affects expression ISO propylparaben affects the expression of E2F3 mRNA CTD PMID:24481588 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G Esr1 estrogen receptor 1 affects binding
increases expression
increases activity
multiple interactions
EXP
ISO
propylparaben binds to ESR1 protein
propylparaben results in increased expression of ESR1 mRNA; propylparaben results in increased expression of ESR1 protein
propylparaben results in increased activity of ESR1 protein
Fulvestrant inhibits the reaction [propylparaben results in increased activity of ESR1 protein]; propylparaben binds to and results in increased activity of ESR1 protein
CTD PMID:11193391 PMID:19063592 PMID:20132880 PMID:22562034 PMID:23567241 More... NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 affects binding
increases expression
multiple interactions
EXP
ISO
propylparaben binds to ESR2 protein
propylparaben results in increased expression of ESR2 mRNA; propylparaben results in increased expression of ESR2 protein
propylparaben binds to and results in increased activity of ESR2 protein
CTD PMID:11193391 PMID:20132880 PMID:23567241 PMID:25128701 PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO propylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
JBrowse link
G Faah fatty acid amide hydrolase decreases activity ISO propylparaben results in decreased activity of FAAH protein CTD PMID:27659731 NCBI chr 5:129,479,774...129,499,018 JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO propylparaben results in increased expression of FABP4 mRNA CTD PMID:22956630 PMID:24155963 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fadd Fas associated via death domain increases expression ISO propylparaben results in increased expression of FADD mRNA CTD PMID:24481588 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fasn fatty acid synthase increases expression ISO propylparaben results in increased expression of FASN mRNA CTD PMID:22956630 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Flg filaggrin multiple interactions ISO FLG gene mutant form affects the abundance of and affects the susceptibility to propylparaben CTD PMID:28525834 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO [Parabens results in increased abundance of propylparaben] which results in decreased secretion of FSHB protein CTD PMID:32122340 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression ISO propylparaben results in increased expression of GPER1 mRNA; propylparaben results in increased expression of GPER1 protein CTD PMID:26253279 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G H2ax H2A.X variant histone increases expression
multiple interactions
ISO propylparaben results in increased expression of H2AX protein modified form
Fulvestrant inhibits the reaction [propylparaben results in increased expression of H2AX protein modified form]
CTD PMID:31939680 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Lep leptin decreases expression
increases expression
ISO propylparaben results in decreased expression of LEP mRNA
propylparaben results in increased expression of LEP mRNA
CTD PMID:22956630 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation ISO propylparaben affects the phosphorylation of MAPK1 protein CTD PMID:26253279 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation ISO propylparaben affects the phosphorylation of MAPK3 protein CTD PMID:26253279 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO propylparaben results in increased expression of MCL1 mRNA CTD PMID:24481588 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
ISO NRG1 protein promotes the reaction [propylparaben results in increased expression of MYC mRNA]; propylparaben promotes the reaction [NRG1 protein results in increased expression of MYC mRNA] CTD PMID:26502914 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO propylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
multiple interactions
EXP
ISO
propylparaben results in increased expression of NR1I2 mRNA
propylparaben binds to and results in increased activity of NR1I2 protein
CTD PMID:31472229 PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO propylparaben results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases activity
ISO [butylparaben co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with propylparaben] results in increased activity of NR3C1 protein; [tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein
propylparaben results in increased activity of NR3C1 protein
CTD PMID:25448277 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO NRG1 protein promotes the reaction [propylparaben results in increased expression of MYC mRNA]; propylparaben promotes the reaction [NRG1 protein results in increased expression of MYC mRNA] CTD PMID:26502914 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Pgr progesterone receptor increases expression ISO propylparaben results in increased expression of PGR mRNA CTD PMID:25128701 PMID:31939680 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects expression EXP propylparaben affects the expression of PPARA mRNA CTD PMID:31472229 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
ISO propylparaben results in increased expression of PPARG mRNA
PPARG protein promotes the reaction [propylparaben binds to and results in increased activity of PPARG protein]; propylparaben binds to and results in increased activity of PPARG protein
CTD PMID:22956630 PMID:24155963 PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases expression ISO propylparaben results in increased expression of RIPK1 mRNA CTD PMID:24481588 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 increases expression ISO propylparaben results in increased expression of RIPK2 mRNA CTD PMID:24481588 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G S100g S100 calcium binding protein G increases expression EXP propylparaben results in increased expression of S100G protein CTD PMID:19654335 NCBI chr  X:31,705,853...31,708,422
Ensembl chr  X:31,705,866...31,708,433
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO propylparaben binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
G Star steroidogenic acute regulatory protein increases expression ISO propylparaben results in increased expression of STAR mRNA CTD PMID:31306770 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [propylparaben results in increased expression of TFF1 mRNA] CTD PMID:16797915 PMID:22562034 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO propylparaben binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO propylparaben binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Tnf tumor necrosis factor increases expression ISO propylparaben results in increased expression of TNF mRNA CTD PMID:24481588 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO propylparaben results in increased expression of TNFRSF10A mRNA CTD PMID:24481588 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO propylparaben results in increased expression of TNFRSF1A mRNA CTD PMID:24481588 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO propylparaben results in increased expression of TNFRSF25 mRNA CTD PMID:24481588 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO propylparaben results in increased expression of TNFSF10 mRNA CTD PMID:24481588 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tp53 tumor protein p53 increases expression ISO propylparaben results in increased expression of TP53 mRNA; propylparaben results in increased expression of TP53 protein CTD PMID:24481588 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 increases expression ISO propylparaben results in increased expression of TP53BP1 protein CTD PMID:31939680 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Tradd TNFRSF1A-associated via death domain increases expression ISO propylparaben results in increased expression of TRADD mRNA CTD PMID:24481588 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        antimicrobial agent 17400
          propylparaben 89
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        aromatic carboxylic acid 11708
                                          benzoic acids 11681
                                            benzoic acid 4157
                                              hydroxybenzoic acid 3562
                                                monohydroxybenzoic acid 1290
                                                  4-hydroxybenzoic acid 622
                                                    4-hydroxybenzoate ester 616
                                                      paraben 616
                                                        propylparaben 89
paths to the root