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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Pranoprofen
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Accession:CHEBI:32040 term browser browse the term
Synonyms:related_synonym: Formula=C15H13NO3;   InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)19-13/h2-7,9H,8H2,1H3,(H,17,18);   InChIKey=TVQZAMVBTVNYLA-UHFFFAOYSA-N;   SMILES=CC(C1=CC2=C(C=C1)OC3=C(C2)C=CC=N3)C(=O)O;   dl-Pranoprofen;   niflan;   oftalar
 alt_id: CHEBI:94417
 xref: CAS:52549-17-4;   Drug_Central:2238;   HMDB:HMDB0041996;   KEGG:D01578;   LINCS:LSM-5110
 xref_mesh: MESH:C043940



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Pranoprofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO pyranoprofen results in increased expression of AIFM1 protein CTD PMID:31765691 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Atm ATM serine/threonine kinase increases phosphorylation ISO pyranoprofen results in increased phosphorylation of ATM protein CTD PMID:31765691 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO pyranoprofen results in increased expression of BAD protein CTD PMID:31765691 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO pyranoprofen results in increased expression of BAX protein CTD PMID:31765691 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO pyranoprofen results in decreased expression of BCL2 protein CTD PMID:31765691 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO pyranoprofen results in decreased expression of BCL2L1 protein CTD PMID:31765691 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]] CTD PMID:16473424 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Casp2 caspase 2 increases activity ISO pyranoprofen results in increased activity of CASP2 protein CTD PMID:31765691 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases activity ISO pyranoprofen results in increased activity of CASP3 protein CTD PMID:31765691 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO pyranoprofen results in increased activity of CASP8 protein CTD PMID:31765691 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO pyranoprofen results in increased activity of CASP9 protein CTD PMID:31765691 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G H2ax H2A.X variant histone increases expression ISO pyranoprofen results in increased expression of H2AX protein CTD PMID:31765691 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Kng1 kininogen 1 multiple interactions ISO B 4162 inhibits the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium] CTD PMID:16473424 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase increases expression ISO pyranoprofen results in increased expression of MLKL protein CTD PMID:31765691 NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO pyranoprofen results in increased activity of PPARG protein CTD PMID:12065695 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO pyranoprofen results in increased expression of PTGS2 mRNA CTD PMID:10594327 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases expression ISO pyranoprofen results in increased expression of RIPK1 protein CTD PMID:31765691 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 increases expression ISO pyranoprofen results in increased expression of RIPK3 protein CTD PMID:31765691 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    chemical entity 19916
      molecular entity 19916
        polyatomic entity 19874
          molecule 19773
            cyclic compound 19583
              polycyclic compound 18880
                heteropolycyclic compound 18334
                  heterotricyclic compound 15667
                    organic heterotricyclic compound 15667
                      pyridochromene 52
                        Pranoprofen 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  organic heteropolycyclic compound 18334
                                    organic heterotricyclic compound 15667
                                      pyridochromene 52
                                        Pranoprofen 18
paths to the root