CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: polaprezinc
Accession: CHEBI:32024
browse the term
Synonyms: related_synonym: Formula=C9H11N4O3Zn; Formula=C9H12N4O3Zn; InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/q;+2/p-2/t7-;/m1./s1; InChIKey=IGXZLYMCFZHNKW-OGFXRTJISA-L; Promac; SMILES=C(C([N-][C@@H](C([O-])=O)CC1=CN=CN1)=O)CN.[Zn+2]; polaprezincum
xref: CAS:107667-60-7; DrugBank:DB09221; KEGG:D01611
xref_mesh: MESH:C061957
xref: PMID:22382829; PMID:2480637; PMID:30396959; Wikipedia:Zinc_L-carnosine
G
Casp3
caspase 3
multiple interactions
EXP
polaprezinc inhibits the reaction [Indomethacin results in increased activity of CASP3 protein]
CTD
PMID:11043455
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
EXP
polaprezinc results in increased expression of HSPA1A protein
CTD
PMID:16949620
NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
EXP
polaprezinc results in increased expression of HSPA1B protein
CTD
PMID:16984587
NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
G
Igf1
insulin-like growth factor 1
increases expression
ISO
polaprezinc results in increased expression of IGF1 mRNA
CTD
PMID:10423164
NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
G
Rgn
regucalcin
increases expression
ISO
polaprezinc results in increased expression of RGN mRNA
CTD
PMID:18327666
NCBI chr X:1,833,484...1,848,904
Ensembl chr X:1,833,492...1,848,904
G
Runx2
RUNX family transcription factor 2
increases expression
ISO
polaprezinc results in increased expression of RUNX2 mRNA
CTD
PMID:18327666
NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
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