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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:polaprezinc
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Accession:CHEBI:32024 term browser browse the term
Synonyms:related_synonym: Formula=C9H11N4O3Zn;   Formula=C9H12N4O3Zn;   InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/q;+2/p-2/t7-;/m1./s1;   InChIKey=IGXZLYMCFZHNKW-OGFXRTJISA-L;   Promac;   SMILES=C(C([N-][C@@H](C([O-])=O)CC1=CN=CN1)=O)CN.[Zn+2];   polaprezincum
 xref: CAS:107667-60-7;   DrugBank:DB09221;   KEGG:D01611
 xref_mesh: MESH:C061957
 xref: PMID:22382829;   PMID:2480637;   PMID:30396959;   Wikipedia:Zinc_L-carnosine


show annotations for term's descendants           Sort by:
polaprezinc term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP polaprezinc inhibits the reaction [Indomethacin results in increased activity of CASP3 protein] CTD PMID:11043455 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP polaprezinc results in increased expression of HSPA1B protein CTD PMID:16984587 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP polaprezinc results in increased expression of HSPA1A protein CTD PMID:16949620 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO polaprezinc results in increased expression of IGF1 mRNA CTD PMID:10423164 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Rgn regucalcin increases expression ISO polaprezinc results in increased expression of RGN mRNA CTD PMID:18327666 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO polaprezinc results in increased expression of RUNX2 mRNA CTD PMID:18327666 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19765
    chemical entity 19763
      group 19727
        organic group 18856
          amino-acid residue 9550
            peptide 9549
              polaprezinc 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19765
    subatomic particle 19763
      composite particle 19763
        hadron 19763
          baryon 19763
            nucleon 19763
              atomic nucleus 19763
                atom 19763
                  main group element atom 19712
                    p-block element atom 19712
                      carbon group element atom 19658
                        carbon atom 19654
                          organic molecular entity 19654
                            organic group 18856
                              organic divalent group 18842
                                organodiyl group 18842
                                  carbonyl group 18807
                                    carbonyl compound 18807
                                      carboxylic acid 18523
                                        carboacyl group 17654
                                          univalent carboacyl group 17654
                                            carbamoyl group 17496
                                              carboxamide 17496
                                                peptide 9549
                                                  polaprezinc 6
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