CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: polaprezinc
Accession: CHEBI:32024
browse the term
Synonyms: related_synonym: Formula=C9H11N4O3Zn; Formula=C9H12N4O3Zn; InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/q;+2/p-2/t7-;/m1./s1; InChIKey=IGXZLYMCFZHNKW-OGFXRTJISA-L; Promac; SMILES=C(C([N-][C@@H](C([O-])=O)CC1=CN=CN1)=O)CN.[Zn+2]; polaprezincum
xref: CAS:107667-60-7; DrugBank:DB09221; KEGG:D01611
xref_mesh: MESH:C061957
xref: PMID:22382829; PMID:2480637; PMID:30396959; Wikipedia:Zinc_L-carnosine
G
Casp3
caspase 3
multiple interactions
EXP
polaprezinc inhibits the reaction [Indomethacin results in increased activity of CASP3 protein]
CTD
PMID:11043455
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression
EXP
polaprezinc results in increased expression of HSPA1B protein
CTD
PMID:16984587
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
EXP
polaprezinc results in increased expression of HSPA1A protein
CTD
PMID:16949620
NCBI chr20:3,870,765...3,873,221
G
Igf1
insulin-like growth factor 1
increases expression
ISO
polaprezinc results in increased expression of IGF1 mRNA
CTD
PMID:10423164
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Rgn
regucalcin
increases expression
ISO
polaprezinc results in increased expression of RGN mRNA
CTD
PMID:18327666
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
G
Runx2
RUNX family transcription factor 2
increases expression
ISO
polaprezinc results in increased expression of RUNX2 mRNA
CTD
PMID:18327666
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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