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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:polaprezinc
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Accession:CHEBI:32024 term browser browse the term
Synonyms:related_synonym: Formula=C9H11N4O3Zn;   Formula=C9H12N4O3Zn;   InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/q;+2/p-2/t7-;/m1./s1;   InChIKey=IGXZLYMCFZHNKW-OGFXRTJISA-L;   Promac;   SMILES=C(C([N-][C@@H](C([O-])=O)CC1=CN=CN1)=O)CN.[Zn+2];   polaprezincum
 xref: CAS:107667-60-7;   DrugBank:DB09221;   KEGG:D01611
 xref_mesh: MESH:C061957
 xref: PMID:22382829;   PMID:2480637;   PMID:30396959;   Wikipedia:Zinc_L-carnosine


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polaprezinc term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP polaprezinc inhibits the reaction [Indomethacin results in increased activity of CASP3 protein] CTD PMID:11043455 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP polaprezinc results in increased expression of HSPA1A protein CTD PMID:16949620 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP polaprezinc results in increased expression of HSPA1B protein CTD PMID:16984587 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO polaprezinc results in increased expression of IGF1 mRNA CTD PMID:10423164 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Rgn regucalcin increases expression ISO polaprezinc results in increased expression of RGN mRNA CTD PMID:18327666 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO polaprezinc results in increased expression of RUNX2 mRNA CTD PMID:18327666 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    chemical entity 19875
      group 19787
        organic group 18569
          amino-acid residue 9409
            peptide 9408
              polaprezinc 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      carbon group element atom 19668
                        carbon atom 19657
                          organic molecular entity 19657
                            organic group 18569
                              organic divalent group 18560
                                organodiyl group 18560
                                  carbonyl group 18468
                                    carbonyl compound 18468
                                      carboxylic acid 18142
                                        carboacyl group 17404
                                          univalent carboacyl group 17404
                                            carbamoyl group 17189
                                              carboxamide 17189
                                                peptide 9408
                                                  polaprezinc 6
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