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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:polaprezinc
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Accession:CHEBI:32024 term browser browse the term
Synonyms:related_synonym: Formula=C9H11N4O3Zn;   Formula=C9H12N4O3Zn;   InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/q;+2/p-2/t7-;/m1./s1;   InChIKey=IGXZLYMCFZHNKW-OGFXRTJISA-L;   Promac;   SMILES=C(C([N-][C@@H](C([O-])=O)CC1=CN=CN1)=O)CN.[Zn+2];   polaprezincum
 xref: CAS:107667-60-7;   DrugBank:DB09221;   KEGG:D01611
 xref_mesh: MESH:C061957
 xref: PMID:22382829;   PMID:2480637;   PMID:30396959;   Wikipedia:Zinc_L-carnosine


show annotations for term's descendants           Sort by:
 
polaprezinc term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP polaprezinc inhibits the reaction [Indomethacin results in increased activity of CASP3 protein] CTD PMID:11043455 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP polaprezinc results in increased expression of HSPA1A protein CTD PMID:16949620
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP polaprezinc results in increased expression of HSPA1B protein CTD PMID:16984587 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO polaprezinc results in increased expression of IGF1 mRNA CTD PMID:10423164 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Rgn regucalcin increases expression ISO polaprezinc results in increased expression of RGN mRNA CTD PMID:18327666 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO polaprezinc results in increased expression of RUNX2 mRNA CTD PMID:18327666 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    chemical entity 20088
      group 19990
        organic group 18988
          amino-acid residue 9505
            peptide 9504
              polaprezinc 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      carboxylic acid 18597
                                        carboacyl group 17730
                                          univalent carboacyl group 17710
                                            carbamoyl group 17550
                                              carboxamide 17570
                                                peptide 9504
                                                  polaprezinc 6
paths to the root