CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: plaunotol
Accession: CHEBI:32023
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Definition: A diterpenoid that is geranylgeraniol carrying an additional hydroxy substituent at position 18.
Synonyms: exact_synonym: (2Z,6E)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-6-methylocta-2,6-diene-1,8-diol
related_synonym: (E,Z,E)-7-Hydroxymethyl-3,11,15-trimethyl-2,6,10,14-hexadecatetraen-1-ol; 18-Hydroxygeranylgeraniol; Formula=C20H34O2; InChI=1S/C20H34O2/c1-17(2)8-5-9-18(3)10-6-12-20(16-22)13-7-11-19(4)14-15-21/h8,10,13-14,21-22H,5-7,9,11-12,15-16H2,1-4H3/b18-10+,19-14+,20-13-; InChIKey=SUWYPNNPLSRNPS-UNTSEYQFSA-N; Kelnac; Plaunotolum; SMILES=CC(C)=CCC\\C(C)=C\\CC\\C(CO)=C\\CC\\C(C)=C\\CO
xref: Beilstein:2217548; CAS:64218-02-6; Drug_Central:2222; KEGG:C13273; KEGG:D01803
xref_mesh: MESH:C047686
xref: MetaCyc:CPD-11423; PMID:10817427; PMID:10824880; PMID:12096020; PMID:17827146; PMID:18805546; PMID:21279879; PMID:21661449; PMID:22752851; PMID:23092673; PMID:24286075; PMID:2471968; PMID:3101705; PMID:8737142; PMID:8889714; PMID:9306259; PMID:9738829; PMID:9785600; Patent:US4059641; Reaxys:2217548
G
Itgam
integrin subunit alpha M
multiple interactions
ISO
plaunotol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGAM protein]
CTD
PMID:10215738
NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
G
Itgb2
integrin subunit beta 2
multiple interactions
ISO
plaunotol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGB2 protein]
CTD
PMID:10215738
NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
G
Tnf
tumor necrosis factor
decreases expression
ISO
plaunotol results in decreased expression of TNF protein
CTD
PMID:10215738
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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