Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Olmesartan medoxomil
go back to main search page
Accession:CHEBI:31932 term browser browse the term
Synonyms:related_synonym: CS-866;   CS866;   Formula=C29H30N6O6;   InChI=1S/C29H30N6O6/c1-5-8-23-30-25(29(3,4)38)24(27(36)39-16-22-17(2)40-28(37)41-22)35(23)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)26-31-33-34-32-26/h6-7,9-14,38H,5,8,15-16H2,1-4H3,(H,31,32,33,34);   InChIKey=UQGKUQLKSCSZGY-UHFFFAOYSA-N;   SMILES=CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)OCC5=C(OC(=O)O5)C)C(C)(C)O;   olmetec
 alt_id: CHEBI:93384
 xref: CAS:144689-63-4;   Drug_Central:1985;   KEGG:D01204;   LINCS:LSM-3767
 xref_mesh: MESH:D000068557


show annotations for term's descendants           Sort by:
 
Olmesartan medoxomil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Olmesartan Medoxomil results in decreased activity of ABCB11 protein CTD PMID:23956101 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of BAX protein] CTD PMID:30594690 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in decreased expression of BCL2 protein] CTD PMID:30594690 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of CASP3 protein] CTD PMID:30594690 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in decreased activity of CAT protein] CTD PMID:30594690 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Olmesartan Medoxomil results in decreased expression of COL1A1 mRNA CTD PMID:18501344 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Crp C-reactive protein multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of CRP protein] CTD PMID:30594690 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Edn1 endothelin 1 decreases expression EXP Olmesartan Medoxomil results in decreased expression of EDN1 mRNA CTD PMID:16336959 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Fasn fatty acid synthase decreases expression EXP Olmesartan Medoxomil results in decreased expression of FASN mRNA CTD PMID:18501344 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in decreased expression of HMOX1 mRNA] CTD PMID:30594690 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il10 interleukin 10 multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in decreased expression of IL10 protein] CTD PMID:30594690 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of IL1B protein] CTD PMID:30594690 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of IL6 protein] CTD PMID:30594690 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased activity of MPO protein]; Olmesartan Medoxomil inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:23665423 PMID:30594690 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in decreased expression of NFE2L2 mRNA] CTD PMID:30594690 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in decreased expression of NFKBIA protein]; Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of NFKBIA mRNA] CTD PMID:30594690 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nppb natriuretic peptide B decreases expression EXP Olmesartan Medoxomil results in decreased expression of NPPB mRNA CTD PMID:16336959 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of RELA mRNA]; Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of RELA protein]; Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased phosphorylation of RELA protein] CTD PMID:30594690 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Olmesartan Medoxomil results in decreased expression of SERPINE1 mRNA CTD PMID:18501344 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP Olmesartan Medoxomil results in decreased expression of SREBF1 mRNA CTD PMID:18501344 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions
EXP Olmesartan Medoxomil results in decreased expression of TGFB1 mRNA
Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of TGFB1 protein]
CTD PMID:16336959 PMID:18501344 PMID:30594690 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
EXP Olmesartan Medoxomil inhibits the reaction [Acetic Acid results in increased expression of TNF protein]; Olmesartan Medoxomil inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]; Olmesartan Medoxomil inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]
Olmesartan Medoxomil results in decreased expression of TNF protein
CTD PMID:18501344 PMID:23665423 PMID:26781185 PMID:30594690 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19767
    chemical entity 19767
      molecular entity 19766
        polyatomic entity 19685
          molecule 19526
            cyclic compound 19359
              ring assembly 7264
                biphenyls 6009
                  Olmesartan medoxomil 22
Path 2
Term Annotations click to browse term
  CHEBI ontology 19767
    subatomic particle 19766
      composite particle 19766
        hadron 19766
          baryon 19766
            nucleon 19766
              atomic nucleus 19766
                atom 19766
                  main group element atom 19657
                    p-block element atom 19657
                      carbon group element atom 19573
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19496
                              organic cyclic compound 19322
                                carbocyclic compound 18299
                                  benzenoid aromatic compound 17404
                                    biphenyls 6009
                                      Olmesartan medoxomil 22
paths to the root