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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Nilvadipine
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Accession:CHEBI:31911 term browser browse the term
Synonyms:related_synonym: FR-34235;   Formula=C19H19N3O6;   InChI=1S/C19H19N3O6/c1-10(2)28-19(24)15-11(3)21-14(9-20)17(18(23)27-4)16(15)12-6-5-7-13(8-12)22(25)26/h5-8,10,16,21H,1-4H3;   InChIKey=FAIIFDPAEUKBEP-UHFFFAOYSA-N;   SMILES=CC1=C(C(C(=C(N1)C#N)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC(C)C;   nivadil;   nivaldipine
 alt_id: CHEBI:95208
 xref: CAS:75530-68-6;   Drug_Central:1934;   HMDB:HMDB0015657;   KEGG:D01908;   LINCS:LSM-6501
 xref_mesh: MESH:C035100


show annotations for term's descendants           Sort by:
Nilvadipine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO nilvadipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin] CTD PMID:11895100 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases activity ISO nilvadipine results in decreased activity of CYP2J2 protein CTD PMID:30965050 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions EXP nilvadipine inhibits the reaction [Cyclosporine results in increased expression of FLT1 mRNA] CTD PMID:12110003 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Nefl neurofilament light chain multiple interactions EXP nilvadipine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] CTD PMID:31969611 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Ren renin multiple interactions EXP nilvadipine inhibits the reaction [Tacrolimus results in increased expression of REN protein] CTD PMID:7533848 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19876
    chemical entity 19905
      group 19832
        pseudohalo group 4555
          cyano group 4555
            nitrile 4555
              Nilvadipine 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19876
    subatomic particle 19874
      composite particle 19874
        hadron 19874
          baryon 19874
            nucleon 19874
              atomic nucleus 19905
                atom 19905
                  main group element atom 19821
                    p-block element atom 19821
                      carbon group element atom 19768
                        carbon atom 19764
                          organic molecular entity 19764
                            organic group 18962
                              organic divalent group 18943
                                organodiyl group 18915
                                  carbonyl group 18869
                                    carbonyl compound 18869
                                      carboxylic acid 18618
                                        monocarboxylic acid 17917
                                          fatty acid 16580
                                            fatty acid derivative 8912
                                              fatty alcohol 6021
                                                secondary fatty alcohol 783
                                                  propan-2-ol 783
                                                    isopropyl ester 768
                                                      Nilvadipine 5
paths to the root