CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Nilvadipine
Accession: CHEBI:31911
browse the term
Synonyms: related_synonym: FR-34235; Formula=C19H19N3O6; InChI=1S/C19H19N3O6/c1-10(2)28-19(24)15-11(3)21-14(9-20)17(18(23)27-4)16(15)12-6-5-7-13(8-12)22(25)26/h5-8,10,16,21H,1-4H3; InChIKey=FAIIFDPAEUKBEP-UHFFFAOYSA-N; SMILES=CC1=C(C(C(=C(N1)C#N)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC(C)C; nivadil; nivaldipine
alt_id: CHEBI:95208
xref: CAS:75530-68-6; Drug_Central:1934; HMDB:HMDB0015657; KEGG:D01908; LINCS:LSM-6501
xref_mesh: MESH:C035100
G
Abcb1a
ATP binding cassette subfamily B member 1A
multiple interactions
ISO
nilvadipine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]
CTD
PMID:11895100
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
G
Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
decreases activity
ISO
nilvadipine results in decreased activity of CYP2J2 protein
CTD
PMID:30965050
NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:111,178,703...111,244,794
G
Flt1
Fms related receptor tyrosine kinase 1
multiple interactions
EXP
nilvadipine inhibits the reaction [Cyclosporine results in increased expression of FLT1 mRNA]
CTD
PMID:12110003
NCBI chr12:12,333,050...12,504,750
Ensembl chr12:7,297,292...7,468,626
G
Nefl
neurofilament light chain
multiple interactions
EXP
nilvadipine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA]
CTD
PMID:31969611
NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
G
Ren
renin
multiple interactions
EXP
nilvadipine inhibits the reaction [Tacrolimus results in increased expression of REN protein]
CTD
PMID:7533848
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489
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