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ONTOLOGY REPORT - ANNOTATIONS


Term:modafinil
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Accession:CHEBI:31859 term browser browse the term
Definition:A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
Synonyms:exact_synonym: rac-2-[(diphenylmethyl)sulfinyl]acetamide
 related_synonym: 2-(benzhydrylsulfinyl)acetamide;   CEP-1538;   CRL 40476;   Provigil;   modafinilo;   modafinilum
 xref: CAS:68693-11-8 "ChemIDplus";   DrugBank:DB00745;   HMDB:HMDB0014883;   KEGG:D01832
 xref_mesh: MESH:C048833
 xref: PMID:17712350 "Europe PMC";   PMID:22537794 "Europe PMC";   PMID:23017017 "Europe PMC";   PMID:23261131 "Europe PMC";   PMID:24109471 "Europe PMC";   PMID:24120858 "Europe PMC";   PMID:24287166 "Europe PMC";   PMID:24530829 "Europe PMC";   Patent:DE2809625;   Patent:US4177290;   Reaxys:1978970 "Reaxys";   Wikipedia:Modafinil


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modafinil term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp5 acid phosphatase 5, tartrate resistant JBrowse link 8 23,142,733 23,149,067 RGD:6480464
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:6480464
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:6480464
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:6480464
G Tnfrsf11a TNF receptor superfamily member 11A JBrowse link 13 25,778,306 25,835,802 RGD:6480464
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      chemical substance 10725
        mixture 9929
          racemate 8658
            modafinil 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                monocarboxylic acid amide 13180
                                                  2-[(diphenylmethyl)sulfinyl]acetamide 9
                                                    armodafinil 9
                                                      modafinil 9
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