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ONTOLOGY REPORT - ANNOTATIONS


Term:methylparaben
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Accession:CHEBI:31835 term browser browse the term
Definition:A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries.
Synonyms:related_synonym: 4-hydroxybenzoic acid methyl ester;   E 218;   E218;   FEMA No. 2710;   Formula=C8H8O3;   INS No. 218;   INS number 218;   InChI=1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3;   InChIKey=LXCFILQKKLGQFO-UHFFFAOYSA-N;   Maseptol;   Metaben;   Methaben;   Methyl 4-hydroxybenzoate;   Methyl butex;   Methyl chemosept;   Methyl parahydroxybenzoate;   Metoxyde;   Moldex;   Nipagin;   Paridol;   Preserval;   SMILES=COC(=O)c1ccc(O)cc1;   Septos;   Solbrol;   Tegosept M;   methyl p-hydroxybenzoate;   methyl paraben;   p-Oxybenzoesauremethylester;   p-carbomethoxyphenol;   p-hydroxybenzoic acid methyl ester;   p-methoxycarbonylphenol
 xref: CAS:99-76-3 "ChemIDplus";   CAS:99-76-3 "NIST Chemistry WebBook";   Drug_Central:1766 "DrugCentral";   HMDB:HMDB0032572;   KEGG:D01400
 xref_mesh: MESH:C015358
 xref: PDBeChem:MPB;   PMID:12115834 "Europe PMC";   PMID:12387298 "Europe PMC";   PMID:16938376 "Europe PMC";   PMID:17306434 "Europe PMC";   PMID:17351650 "Europe PMC";   PMID:22734461 "Europe PMC";   PMID:23068419 "Europe PMC";   PMID:23324734 "Europe PMC";   PMID:24083322 "Europe PMC";   PMID:6631690 "Europe PMC";   PMID:7334386 "Europe PMC";   Wikipedia:Methylparaben


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methylparaben term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aars2 alanyl-tRNA synthetase 2, mitochondrial JBrowse link 9 17,869,301 17,881,762 RGD:6480464
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 10 39,654,771 39,717,592 RGD:6480464
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:6480464
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:6480464
G Alpl alkaline phosphatase, biomineralization associated JBrowse link 5 156,086,496 156,141,513 RGD:6480464
G Arhgap9 Rho GTPase activating protein 9 JBrowse link 7 70,612,650 70,620,900 RGD:6480464
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:6480464
G Atp5mg ATP synthase membrane subunit g JBrowse link 8 49,220,441 49,227,273 RGD:6480464
G Atr ATR serine/threonine kinase JBrowse link 8 103,673,578 103,770,886 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:6480464
G Bcl2l2 Bcl2-like 2 JBrowse link 15 33,543,774 33,549,165 RGD:6480464
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:6480464
G Calb2 calbindin 2 JBrowse link 19 41,482,743 41,509,617 RGD:6480464
G Ccna1 cyclin A1 JBrowse link 2 144,456,689 144,503,570 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:6480464
G Cdc25a cell division cycle 25A JBrowse link 8 117,953,223 117,971,552 RGD:6480464
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:6480464
G Cdk6 cyclin-dependent kinase 6 JBrowse link 4 27,781,728 27,969,653 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdx1 caudal type homeo box 1 JBrowse link 18 56,337,485 56,355,477 RGD:6480464
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:6480464
G Celf5 CUGBP, Elav-like family member 5 JBrowse link 7 11,095,449 11,119,941 RGD:6480464
G Chst1 carbohydrate sulfotransferase 1 JBrowse link 3 81,441,785 81,512,829 RGD:6480464
G Col10a1 collagen type X alpha 1 chain JBrowse link 20 41,180,295 41,190,664 RGD:6480464
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:6480464
G Col8a1 collagen type VIII alpha 1 chain JBrowse link 11 44,877,690 45,006,203 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G E2f3 E2F transcription factor 3 JBrowse link 17 36,334,136 36,408,831 RGD:6480464
G Efna4 ephrin A4 JBrowse link 2 188,655,920 188,660,179 RGD:6480464
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:6480464
G Esrrg estrogen-related receptor gamma JBrowse link 13 106,063,799 106,683,353 RGD:6480464
G Flg filaggrin JBrowse link 2 193,565,401 193,574,297 RGD:6480464
G Fus FUS RNA binding protein JBrowse link 1 199,412,805 199,426,705 RGD:6480464
G Gja4 gap junction protein, alpha 4 JBrowse link 5 145,374,688 145,377,221 RGD:6480464
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:6480464
G Greb1 growth regulating estrogen receptor binding 1 JBrowse link 6 41,932,941 42,002,770 RGD:6480464
G Has1 hyaluronan synthase 1 JBrowse link 1 59,720,612 59,732,409 RGD:6480464
G Has2 hyaluronan synthase 2 JBrowse link 7 96,438,046 96,464,049 RGD:6480464
G Hoxc6 homeo box C6 JBrowse link 7 144,612,230 144,626,036 RGD:6480464
G Hps6 HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 JBrowse link 1 265,761,818 265,764,427 RGD:6480464
G Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 JBrowse link 8 70,630,546 70,685,882 RGD:6480464
G Il17rb interleukin 17 receptor B JBrowse link 16 6,064,287 6,077,978 RGD:6480464
G Il24 interleukin 24 JBrowse link 13 47,618,451 47,623,849 RGD:6480464
G Incenp inner centromere protein JBrowse link 1 225,923,448 225,953,384 RGD:6480464
G Ivl involucrin JBrowse link 2 192,761,171 192,773,346 RGD:6480464
G Kcnc1 potassium voltage-gated channel subfamily C member 1 JBrowse link 1 102,414,352 102,456,718 RGD:6480464
G Kcnf1 potassium voltage-gated channel modifier subfamily F member 1 JBrowse link 6 42,471,060 42,473,738 RGD:6480464
G Krt8 keratin 8 JBrowse link 7 143,596,511 143,603,745 RGD:6480464
G Krt82 keratin 82 JBrowse link 7 143,196,282 143,206,138 RGD:6480464
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Lmod1 leiomodin 1 JBrowse link 13 52,147,099 52,189,835 RGD:6480464
G LOC686683 similar to olfactory receptor 73 JBrowse link 3 76,186,104 76,187,045 RGD:6480464
G Lrrc29 leucine rich repeat containing 29 JBrowse link 19 37,266,782 37,282,076 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Masp1 mannan-binding lectin serine peptidase 1 JBrowse link 11 80,736,424 80,806,278 RGD:6480464
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:6480464
G Meox1 mesenchyme homeobox 1 JBrowse link 10 89,797,011 89,817,009 RGD:6480464
G Nanog Nanog homeobox JBrowse link 4 155,531,906 155,539,268 RGD:6480464
G Ncoa2 nuclear receptor coactivator 2 JBrowse link 5 5,466,544 5,696,540 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Otof otoferlin JBrowse link 6 27,328,343 27,424,864 RGD:6480464
G Pax3 paired box 3 JBrowse link 9 84,004,004 84,101,226 RGD:6480464
G Pcdha3 protocadherin alpha 3 JBrowse link 18 29,966,245 30,215,896 RGD:6480464
G Pcdhgc3 protocadherin gamma subfamily C, 3 JBrowse link 18 30,954,552 30,971,113 RGD:6480464
G Pex14 peroxisomal biogenesis factor 14 JBrowse link 5 165,782,895 165,918,445 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:6480464
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:6480464
G Shbg sex hormone binding globulin JBrowse link 10 56,219,861 56,237,354 RGD:6480464
G Siah2 siah E3 ubiquitin protein ligase 2 JBrowse link 2 148,874,151 148,891,900 RGD:6480464
G Smc1a structural maintenance of chromosomes 1A JBrowse link X 21,710,976 21,755,708 RGD:6480464
G Sox15 SRY-box transcription factor 15 JBrowse link 10 56,260,514 56,263,503 RGD:6480464
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:6480464
G Sp5 Sp5 transcription factor JBrowse link 3 56,766,475 56,769,277 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
G Susd3 sushi domain containing 3 JBrowse link 17 15,814,132 15,830,328 RGD:6480464
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:6480464
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link 9 20,546,159 20,621,051 RGD:6480464
G Ubd ubiquitin D JBrowse link 20 1,876,175 1,878,126 RGD:6480464
G Vill villin-like JBrowse link 8 127,735,233 127,753,313 RGD:6480464
G Wnk4 WNK lysine deficient protein kinase 4 JBrowse link 10 89,181,139 89,198,213 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:6480464
G Zfp397 zinc finger protein 397 JBrowse link 18 15,856,841 15,865,574 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        antimicrobial agent 17148
          antifungal agent 14605
            methylparaben 94
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      carboxylic acid 17918
                                        aromatic carboxylic acid 10681
                                          benzoic acids 10645
                                            benzoic acid 3372
                                              hydroxybenzoic acid 2743
                                                monohydroxybenzoic acid 833
                                                  4-hydroxybenzoic acid 148
                                                    4-hydroxybenzoate ester 143
                                                      paraben 143
                                                        methylparaben 94
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.