|
G |
A1bg |
alpha-1-B glycoprotein |
increases expression |
ISO |
Mercuric Chloride results in increased expression of A1BG mRNA |
CTD |
PMID:11267658 |
|
NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097
|
|
G |
A2m |
alpha-2-macroglobulin |
increases expression |
ISO |
Mercuric Chloride results in increased expression of A2M mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
|
|
G |
Abcb1b |
ATP-binding cassette, sub-family B member 1B |
increases expression |
EXP ISO |
Mercuric Chloride results in increased expression of ABCB1B mRNA |
CTD |
PMID:28536007 PMID:31175882 |
|
NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
|
|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression multiple interactions decreases response to substance |
ISO EXP |
Mercuric Chloride results in increased expression of ABCC1 mRNA Mercuric Chloride results in increased expression of and affects the localization of ABCC1 protein; SB 203580 inhibits the reaction [Mercuric Chloride results in increased expression of and affects the localization of ABCC1 protein]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Mercuric Chloride] Mercuric Chloride results in increased expression of ABCC1 protein |
CTD |
PMID:10685512 PMID:15585369 PMID:21783896 PMID:30031051 |
|
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
decreases response to substance multiple interactions affects response to substance increases expression affects expression |
ISO EXP |
ABCC2 protein results in decreased susceptibility to Mercuric Chloride ABCC2 protein affects the reaction [Succimer binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]]; ABCC2 protein affects the reaction [Unithiol binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]]; ABCC2 protein binds to and results in increased secretion of [Succimer binds to [Mercuric Chloride binds to Cysteine]]; ABCC2 protein binds to and results in increased secretion of [Unithiol binds to [Mercuric Chloride binds to Cysteine]] ABCC2 gene mutant form affects the susceptibility to Mercuric Chloride ABCC2 gene mutant form promotes the reaction [Mercuric Chloride results in increased expression of GCLM mRNA] Mercuric Chloride results in increased expression of ABCC2 mRNA Mercuric Chloride affects the expression of ABCC2 mRNA |
CTD |
PMID:18511429 PMID:21783896 PMID:24039982 PMID:25145654 PMID:27720909 PMID:28536007 PMID:32599119 More...
|
|
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
|
|
G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
increases expression |
ISO EXP |
Mercuric Chloride results in increased expression of ABCC4 mRNA |
CTD |
PMID:27720909 PMID:28536007 PMID:31175882 |
|
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
|
|
G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
increases expression increases response to substance affects export |
ISO EXP |
Mercuric Chloride results in increased expression of ABCG2 mRNA ABCG2 gene mutant form results in increased susceptibility to Mercuric Chloride ABCG2 protein affects the export of Mercuric Chloride |
CTD |
PMID:24118919 PMID:25868844 PMID:31175882 |
|
NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
|
|
G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of ABCG8 mRNA |
CTD |
PMID:31175882 |
|
NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
|
|
G |
Abhd17c |
abhydrolase domain containing 17C, depalmitoylase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of ABHD17C mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:138,084,632...138,125,595
Ensembl chr 1:138,084,634...138,125,595
|
|
G |
Ache |
acetylcholinesterase |
multiple interactions decreases activity |
EXP |
[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased activity of ACHE protein; [zinc chloride co-treated with Sodium Selenite] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased activity of ACHE protein]; cupric chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ACHE protein] |
CTD |
PMID:24799335 PMID:36646412 |
|
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
|
|
G |
Acot1 |
acyl-CoA thioesterase 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ACOT1 protein |
CTD |
PMID:37172713 |
|
NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
|
|
G |
Acss3 |
acyl-CoA synthetase short-chain family member 3 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ACSS3 protein |
CTD |
PMID:37172713 |
|
NCBI chr 7:42,241,261...42,450,209
Ensembl chr 7:42,242,652...42,450,230
|
|
G |
Actb |
actin, beta |
increases expression decreases expression |
ISO |
Mercuric Chloride results in increased expression of ACTB mRNA Mercuric Chloride results in decreased expression of ACTB protein |
CTD |
PMID:20452446 |
|
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
|
|
G |
Actn2 |
actinin alpha 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ACTN2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
|
|
G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ADAMTS1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
|
|
G |
Adcyap1r1 |
ADCYAP receptor type I |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ADCYAP1R1 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700
|
|
G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ADIPOQ mRNA |
CTD |
PMID:30807803 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
|
|
G |
Adm |
adrenomedullin |
increases expression multiple interactions |
EXP |
Mercuric Chloride results in increased expression of ADM mRNA; Mercuric Chloride results in increased expression of ADM protein Fingolimod Hydrochloride promotes the reaction [Mercuric Chloride results in increased expression of ADM mRNA]; Fingolimod Hydrochloride promotes the reaction [Mercuric Chloride results in increased expression of ADM protein]; Mycophenolic Acid inhibits the reaction [Mercuric Chloride results in increased expression of ADM protein] |
CTD |
PMID:15063164 PMID:15680492 PMID:16507785 |
|
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
|
|
G |
Adora1 |
adenosine A1 receptor |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of ADORA1 protein |
CTD |
PMID:10677590 |
|
NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
|
|
G |
Adtrp |
androgen-dependent TFPI-regulating protein |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of ADTRP mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826
|
|
G |
Aff3 |
ALF transcription elongation factor 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of AFF3 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 9:40,399,099...40,856,716
Ensembl chr 9:40,404,375...40,857,247
|
|
G |
Aff4 |
ALF transcription elongation factor 4 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of AFF4 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751
|
|
G |
Afg1l |
AFG1 like ATPase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of AFG1L mRNA |
CTD |
PMID:16507785 |
|
NCBI chr20:45,798,344...45,967,997
Ensembl chr20:45,798,349...45,967,906
|
|
G |
Ago2 |
argonaute RISC catalytic component 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of AGO2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
|
|
G |
Agrn |
agrin |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [AGRN protein results in increased phosphorylation of CHRNB1 protein] |
CTD |
PMID:15045580 |
|
NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
|
|
G |
Agt |
angiotensinogen |
increases expression |
EXP |
Mercuric Chloride results in increased expression of AGT protein; Mercuric Chloride results in increased expression of AGT protein modified form |
CTD |
PMID:18093879 PMID:22822941 |
|
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
|
|
G |
Agtr1a |
angiotensin II receptor, type 1a |
increases expression |
EXP |
Mercuric Chloride results in increased expression of AGTR1A mRNA |
CTD |
PMID:28987480 |
|
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
|
|
G |
Agxt |
alanine--glyoxylate aminotransferase |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of AGXT mRNA |
CTD |
PMID:37172713 |
|
NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
|
|
G |
Ahnak2 |
AHNAK nucleoprotein 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of AHNAK2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 6:131,830,668...131,876,311
Ensembl chr 6:131,831,454...131,854,463
|
|
G |
Akap17a |
A-kinase anchoring protein 17A |
increases expression |
EXP |
Mercuric Chloride results in increased expression of AKAP17A mRNA |
CTD |
PMID:16507785 |
|
NCBI chr12:16,310,427...16,315,166
Ensembl chr12:16,310,437...16,314,479
|
|
G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of AKR1C1 mRNA |
CTD |
PMID:38568856 |
|
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
|
|
G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of AKR1C2 mRNA |
CTD |
PMID:38568856 |
|
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
|
|
G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of AKR1C3 mRNA |
CTD |
PMID:38568856 |
|
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
|
|
G |
Akr7a3 |
aldo-keto reductase family 7 member A3 |
multiple interactions |
EXP |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of AKR7A3 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of AKR7A3 protein |
CTD |
PMID:29298499 |
|
NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Mercuric Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:16731823 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
|
|
G |
Alad |
aminolevulinate dehydratase |
multiple interactions decreases expression decreases activity increases activity |
ISO EXP |
[Mercuric Chloride co-treated with diphenyldiselenide] results in decreased activity of ALAD protein; [zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]] which affects the abundance of Mercury; Cadmium Chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; diphenyldiselenide inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; Mercuric Chloride promotes the reaction [Sodium Selenite results in decreased activity of ALAD protein]; Sodium Selenite promotes the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein] Mercuric Chloride results in decreased expression of ALAD protein Mercuric Chloride results in increased activity of ALAD protein lycopene inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]; zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of ALAD protein] |
CTD |
PMID:12595158 PMID:14615064 PMID:14630126 PMID:17516994 PMID:21259295 PMID:22413763 PMID:24619859 PMID:24679358 PMID:24954677 PMID:24970117 More...
|
|
NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
|
|
G |
Alb |
albumin |
affects binding increases expression multiple interactions decreases expression |
ISO EXP |
Mercuric Chloride binds to ALB protein Mercuric Chloride results in increased expression of ALB protein [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate co-treated with Mercuric Chloride co-treated with chromium trioxide co-treated with nickel chloride co-treated with manganese chloride co-treated with ferric chloride] results in decreased expression of ALB protein; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]; Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]]; Selenium inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]] |
CTD |
PMID:17489621 PMID:17657459 PMID:21549428 PMID:24485406 PMID:37172713 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
|
|
G |
Aldh18a1 |
aldehyde dehydrogenase 18 family, member A1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ALDH18A1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
|
|
G |
Aldh3a1 |
aldehyde dehydrogenase 3 family, member A1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of ALDH3A1 mRNA |
CTD |
PMID:38568856 |
|
NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
|
|
G |
Aldh6a1 |
aldehyde dehydrogenase 6 family, member A1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ALDH6A1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
|
|
G |
Alkbh5 |
alkB homolog 5, RNA demethylase |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ALKBH5 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:45,344,888...45,366,331
Ensembl chr10:45,343,395...45,366,331
|
|
G |
Amacr |
alpha-methylacyl-CoA racemase |
decreases expression multiple interactions |
EXP ISO |
Mercuric Chloride results in decreased expression of AMACR mRNA [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AMACR mRNA |
CTD |
PMID:16507785 PMID:27188386 |
|
NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
|
|
G |
Amer2 |
APC membrane recruitment protein 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of AMER2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr15:34,525,352...34,535,660
Ensembl chr15:34,524,542...34,528,455
|
|
G |
Anapc5 |
anaphase-promoting complex subunit 5 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ANAPC5 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr12:33,748,709...33,781,709
Ensembl chr12:33,748,735...33,781,781
|
|
G |
Angpt1 |
angiopoietin 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of ANGPT1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
|
|
G |
Ankrd10 |
ankyrin repeat domain 10 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ANKRD10 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr16:77,866,489...77,889,745
Ensembl chr16:77,864,261...77,889,745
|
|
G |
Ankrd66 |
ankyrin repeat domain 66 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ANKRD66 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 9:17,421,432...17,441,212
Ensembl chr 9:17,411,983...17,442,647
|
|
G |
Anxa5 |
annexin A5 |
multiple interactions |
ISO |
ANXA5 protein inhibits the reaction [Mercuric Chloride results in increased activity of F3 protein] |
CTD |
PMID:17726162 |
|
NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
|
|
G |
Apob |
apolipoprotein B |
increases expression |
ISO |
Mercuric Chloride results in increased expression of APOB mRNA |
CTD |
PMID:37172713 |
|
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
|
|
G |
App |
amyloid beta precursor protein |
multiple interactions increases secretion |
ISO |
Melatonin inhibits the reaction [Mercuric Chloride results in increased secretion of APP protein modified form] |
CTD |
PMID:10617124 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
|
|
G |
Aqp1 |
aquaporin 1 |
affects activity multiple interactions decreases activity |
ISO EXP |
Mercuric Chloride affects the activity of AQP1 protein Mercuric Chloride inhibits the reaction [AQP1 protein results in increased transport of Water] Mercuric Chloride results in decreased activity of AQP1 protein |
CTD |
PMID:7528928 PMID:8457558 PMID:10559675 PMID:11468359 PMID:19539607 |
|
NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
|
|
G |
Aqp11 |
aquaporin 11 |
multiple interactions |
ISO |
Mercaptoethanol inhibits the reaction [Mercuric Chloride inhibits the reaction [AQP11 protein results in increased transport of Water]]; Mercuric Chloride inhibits the reaction [AQP11 protein results in increased transport of Water] |
CTD |
PMID:21251984 |
|
NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725
|
|
G |
Aqp3 |
aquaporin 3 (Gill blood group) |
decreases activity multiple interactions decreases expression |
ISO EXP |
Mercuric Chloride results in decreased activity of AQP3 protein Mercaptoethanol inhibits the reaction [Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]]; Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]; Mercuric Chloride inhibits the reaction [Dexamethasone promotes the reaction [AQP3 protein results in increased transport of Water]] Mercuric Chloride results in decreased expression of AQP3 mRNA; Mercuric Chloride results in decreased expression of AQP3 protein |
CTD |
PMID:9124401 PMID:9374739 PMID:19513079 PMID:22687538 PMID:25766885 PMID:25854323 More...
|
|
NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
|
|
G |
Aqp4 |
aquaporin 4 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of AQP4 mRNA; Mercuric Chloride results in decreased expression of AQP4 protein |
CTD |
PMID:25854323 |
|
NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
|
|
G |
Aqp7 |
aquaporin 7 |
decreases activity multiple interactions decreases expression |
ISO EXP |
Mercuric Chloride results in decreased activity of AQP7 protein Mercaptoethanol inhibits the reaction [Mercuric Chloride results in decreased activity of AQP7 protein] Mercuric Chloride results in decreased expression of AQP7 protein |
CTD |
PMID:10777495 PMID:25854323 |
|
NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
|
|
G |
Aqp8 |
aquaporin 8 |
decreases activity multiple interactions |
ISO |
Mercuric Chloride results in decreased activity of AQP8 protein Mercuric Chloride inhibits the reaction [AQP8 protein results in increased transport of Water] |
CTD |
PMID:19840149 |
|
NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
|
|
G |
Aqp9 |
aquaporin 9 |
multiple interactions decreases activity |
EXP ISO |
Mercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water] Mercuric Chloride results in decreased activity of AQP9 protein |
CTD |
PMID:9514918 PMID:9733774 PMID:10205677 PMID:22114114 |
|
NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
|
|
G |
Arb2a |
ARB2 cotranscriptional regulator A |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ARB2A mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 2:7,553,873...8,018,183
Ensembl chr 2:7,553,891...8,018,162
|
|
G |
Arc |
activity-regulated cytoskeleton-associated protein |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ARC mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
|
|
G |
Arf5 |
ARF GTPase 5 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ARF5 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:57,038,521...57,041,447
Ensembl chr 4:57,038,521...57,041,441
|
|
G |
Arfgef3 |
ARFGEF family member 3 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ARFGEF3 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:13,245,578...13,404,319
Ensembl chr 1:13,244,830...13,404,084
|
|
G |
Arg2 |
arginase 2 |
decreases response to substance multiple interactions |
ISO EXP |
ARG2 protein results in decreased susceptibility to Mercuric Chloride Mercuric Chloride results in decreased expression of and results in decreased activity of ARG2 protein |
CTD |
PMID:17874066 |
|
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
|
|
G |
Arl5b |
ARF like GTPase 5B |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ARL5B mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854
|
|
G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ASNS mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
|
|
G |
Aspa |
aspartoacylase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of ASPA mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:57,891,704...57,945,267
Ensembl chr10:57,892,104...57,945,272
|
|
G |
Atf3 |
activating transcription factor 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ATF3 mRNA; Mercuric Chloride results in increased expression of ATF3 protein |
CTD |
PMID:16507785 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
|
|
G |
Atp11b |
ATPase phospholipid transporting 11B (putative) |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ATP11B mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 2:118,585,348...118,691,076
Ensembl chr 2:118,585,342...118,690,232
|
|
G |
Atp13a5 |
ATPase 13A5 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ATP13A5 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr11:71,376,388...71,515,789
Ensembl chr11:71,376,422...71,515,789
|
|
G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of ATP1A1 protein |
CTD |
PMID:16189294 PMID:21723307 |
|
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
|
|
G |
B2m |
beta-2 microglobulin |
multiple interactions |
ISO |
B2M protein affects the reaction [Mercuric Chloride results in increased expression of IFNG mRNA]; B2M protein affects the reaction [Mercuric Chloride results in increased expression of IL4 mRNA] |
CTD |
PMID:21793797 |
|
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
|
|
G |
B3gat1 |
beta-1,3-glucuronyltransferase 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of B3GAT1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395
|
|
G |
Bace2 |
beta-secretase 2 |
affects expression |
ISO |
Mercuric Chloride affects the expression of BACE2 mRNA |
CTD |
PMID:24118919 |
|
NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546
|
|
G |
Bad |
BCL2-associated agonist of cell death |
increases expression |
ISO |
Mercuric Chloride results in increased expression of BAD protein |
CTD |
PMID:21373768 |
|
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
|
|
G |
Bag2 |
BAG cochaperone 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of BAG2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721
|
|
G |
Bag3 |
BAG cochaperone 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of BAG3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
|
|
G |
Bambi |
BMP and activin membrane-bound inhibitor |
increases expression |
EXP |
Mercuric Chloride results in increased expression of BAMBI mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases activity increases expression |
ISO EXP |
GSK3B protein promotes the reaction [Mercuric Chloride results in increased activity of BAX protein] alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of BAX protein]; Berberine inhibits the reaction [Mercuric Chloride results in increased expression of BAX protein] |
CTD |
PMID:22785175 PMID:25600690 PMID:32134168 PMID:37172713 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
|
|
G |
Bche |
butyrylcholinesterase |
decreases activity |
ISO |
Mercuric Chloride results in decreased activity of BCHE protein |
CTD |
PMID:17355286 |
|
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression increases expression multiple interactions |
ISO EXP |
Mercuric Chloride results in decreased expression of BCL2 mRNA; Mercuric Chloride results in decreased expression of BCL2 protein Mercuric Chloride results in increased expression of BCL2 protein Mercuric Chloride results in increased expression of BCL2 mRNA Berberine inhibits the reaction [Mercuric Chloride results in decreased expression of BCL2 protein] |
CTD |
PMID:8872981 PMID:11068922 PMID:21373768 PMID:23202902 PMID:24751971 PMID:25600690 PMID:37172713 More...
|
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G |
Bcl2l1 |
Bcl2-like 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of BCL2L1 mRNA |
CTD |
PMID:8872981 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
[Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of BDNF mRNA |
CTD |
PMID:21084432 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
|
|
G |
Bhmt |
betaine-homocysteine S-methyltransferase |
multiple interactions |
ISO |
[Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of BHMT mRNA |
CTD |
PMID:21084432 |
|
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
|
|
G |
Bicdl1 |
BICD family like cargo adaptor 1 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BICDL1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr12:40,878,190...41,001,152
Ensembl chr12:40,876,884...40,966,130
|
|
G |
Bmpr2 |
bone morphogenetic protein receptor type 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of BMPR2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
|
|
G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of BTG2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
|
|
G |
Btg3 |
BTG anti-proliferation factor 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of BTG3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
|
|
G |
C13h1orf53 |
similar to human chromosome 1 open reading frame 53 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C1ORF53 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr13:50,413,785...50,418,974
Ensembl chr13:50,413,785...50,419,120
|
|
G |
C19h1orf198 |
similar to human chromosome 1 open reading frame 198 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of C19H1ORF198 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr19:52,604,060...52,629,436
Ensembl chr19:52,604,060...52,629,436
|
|
G |
C3 |
complement C3 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of C3 mRNA |
CTD |
PMID:22136142 |
|
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
|
|
G |
Cacybp |
calcyclin binding protein |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CACYBP mRNA |
CTD |
PMID:16507785 |
|
NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
|
|
G |
Car14 |
carbonic anhydrase 14 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CAR14 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693
|
|
G |
Cars1 |
cysteinyl-tRNA synthetase 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CARS1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
|
|
G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA] |
CTD |
PMID:28453771 |
|
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
|
|
G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases expression decreases expression increases cleavage decreases activity |
ISO EXP |
Mercuric Chloride inhibits the reaction [FAS affects the activity of CASP3 protein] 4-phenylbutyric acid inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 protein modified form]; [Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP3 protein; Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP3 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of CASP3 protein]; GSK3B protein promotes the reaction [Mercuric Chloride results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [Mercuric Chloride results in increased activity of CASP3 protein]; Silymarin inhibits the reaction [Mercuric Chloride results in increased activity of CASP3 protein] [lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of CASP3 protein; [zinc chloride co-treated with lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of CASP3 protein; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 protein]; Berberine inhibits the reaction [Mercuric Chloride results in increased activity of CASP3 protein]; Berberine inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 mRNA]; Mercuric Chloride inhibits the reaction [Gliotoxin results in increased activity of CASP3 protein]; Mercuric Chloride inhibits the reaction [S-nitro-N-acetylpenicillamine inhibits the reaction [Doxorubicin results in increased activity of and results in increased cleavage of CASP3 protein]] Mercuric Chloride results in increased expression of CASP3 mRNA; Mercuric Chloride results in increased expression of CASP3 protein; Mercuric Chloride results in increased expression of CASP3 protein modified form Mercuric Chloride results in decreased expression of CASP3 mRNA Mercuric Chloride results in decreased activity of CASP3 protein |
CTD |
PMID:12504520 PMID:12505371 PMID:15050407 PMID:15150681 PMID:15585371 PMID:15623433 PMID:16273840 PMID:17363214 PMID:20958918 PMID:21373768 PMID:22785175 PMID:22909951 PMID:23202902 PMID:25600690 PMID:26272509 PMID:32134168 PMID:32879258 PMID:33460233 PMID:36646412 PMID:37172713 More...
|
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
|
|
G |
Casp7 |
caspase 7 |
multiple interactions increases expression |
ISO |
[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein; Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein] Mercuric Chloride results in increased expression of CASP7 mRNA |
CTD |
PMID:22909951 PMID:23202902 |
|
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
|
|
G |
Casp8 |
caspase 8 |
multiple interactions increases activity |
ISO |
[Mercuric Chloride co-treated with sodium arsenite co-treated with Cadmium Chloride] results in increased activity of CASP8 protein Mercuric Chloride results in increased activity of CASP8 protein |
CTD |
PMID:16421179 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
|
|
G |
Casp9 |
caspase 9 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CASP9 protein |
CTD |
PMID:21373768 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
|
|
G |
Cat |
catalase |
increases activity increases expression multiple interactions decreases activity decreases expression affects activity |
EXP ISO |
Mercuric Chloride results in increased activity of CAT protein Mercuric Chloride results in increased expression of CAT protein [Mercuric Chloride co-treated with diphenyldiselenide] results in decreased activity of CAT protein Mercuric Chloride results in decreased activity of CAT protein Mercuric Chloride results in decreased expression of CAT protein mangiferin inhibits the reaction [Mercuric Chloride results in decreased expression of CAT protein] [lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased activity of CAT protein; [Vitamin E co-treated with Sodium Selenite] inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; [zinc chloride co-treated with Sodium Selenite] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; allyl sulfide inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Berberine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Mercuric Chloride results in increased activity of CAT protein]; Plant Extracts inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Selenium inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]]; Sodium Selenite inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein] Mercuric Chloride affects the activity of CAT protein |
CTD |
PMID:15977196 PMID:17516994 PMID:19427169 PMID:20629087 PMID:20820944 PMID:21259295 PMID:21787585 PMID:22351102 PMID:22416658 PMID:23369933 PMID:24485406 PMID:24555655 PMID:24751971 PMID:24970117 PMID:25368988 PMID:25600690 PMID:26215012 PMID:26825963 PMID:33460233 PMID:36646412 PMID:37172713 More...
|
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
|
|
G |
Cbl |
Cbl proto-oncogene |
multiple interactions decreases expression |
ISO |
Mercuric Chloride promotes the reaction [HCK protein results in increased phosphorylation of CBL protein] Mercuric Chloride results in decreased expression of CBL mRNA |
CTD |
PMID:10092522 PMID:27188386 |
|
NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
|
|
G |
Cc2d2b |
coiled-coil and C2 domain containing 2B |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of CC2D2B mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:239,561,506...239,655,771
Ensembl chr 1:239,561,987...239,682,416
|
|
G |
Ccdc186 |
coiled-coil domain containing 186 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CCDC186 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:255,831,663...255,871,954
Ensembl chr 1:255,839,595...255,871,935
|
|
G |
Ccl11 |
C-C motif chemokine ligand 11 |
decreases expression increases expression |
ISO |
Mercuric Chloride results in decreased expression of CCL11 protein Mercuric Chloride results in increased expression of CCL11 protein |
CTD |
PMID:21984480 |
|
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases response to substance increases expression multiple interactions |
EXP ISO |
CCL2 protein results in increased susceptibility to Mercuric Chloride Mercuric Chloride results in increased expression of CCL2 mRNA; Mercuric Chloride results in increased expression of CCL2 protein Mercuric Chloride inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein] |
CTD |
PMID:12834626 PMID:36416909 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
|
|
G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CCL20 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
|
|
G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression multiple interactions |
ISO |
Mercuric Chloride results in increased expression of CCL3 protein Mercuric Chloride inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] |
CTD |
PMID:21984480 PMID:36416909 |
|
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
|
|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression increases response to substance |
EXP |
Mercuric Chloride results in increased expression of CCL5 mRNA; Mercuric Chloride results in increased expression of CCL5 protein CCL5 protein results in increased susceptibility to Mercuric Chloride |
CTD |
PMID:12834626 |
|
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
|
|
G |
Ccn1 |
cellular communication network factor 1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CCN1 mRNA |
CTD |
PMID:38568856 |
|
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
|
|
G |
Ccn2 |
cellular communication network factor 2 |
decreases expression increases expression |
EXP ISO |
Mercuric Chloride results in decreased expression of CCN2 mRNA Mercuric Chloride results in increased expression of CCN2 mRNA |
CTD |
PMID:16507785 PMID:38568856 |
|
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
|
|
G |
Ccnb2 |
cyclin B2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CCNB2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
|
|
G |
Ccnh |
cyclin H |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CCNH protein |
CTD |
PMID:37172713 |
|
NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819
|
|
G |
Ccnt1 |
cyclin T1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of CCNT1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
|
|
G |
Ccr1 |
C-C motif chemokine receptor 1 |
increases expression increases response to substance |
EXP |
Mercuric Chloride results in increased expression of CCR1 mRNA; Mercuric Chloride results in increased expression of CCR1 protein CCR1 protein results in increased susceptibility to Mercuric Chloride |
CTD |
PMID:12834626 |
|
NCBI chr 8:123,556,286...123,561,841
|
|
G |
Ccr2 |
C-C motif chemokine receptor 2 |
increases expression increases response to substance |
EXP |
Mercuric Chloride results in increased expression of CCR2 mRNA; Mercuric Chloride results in increased expression of CCR2 protein CCR2 protein results in increased susceptibility to Mercuric Chloride |
CTD |
PMID:12834626 |
|
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
|
|
G |
Ccr5 |
C-C motif chemokine receptor 5 |
increases expression increases response to substance |
EXP |
Mercuric Chloride results in increased expression of CCR5 mRNA; Mercuric Chloride results in increased expression of CCR5 protein CCR5 protein results in increased susceptibility to Mercuric Chloride |
CTD |
PMID:12834626 |
|
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
|
|
G |
Cd22 |
CD22 molecule |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [CD22 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Mercuric Chloride inhibits the reaction [CD22 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Mercuric Chloride promotes the reaction [CD22 protein results in increased phosphorylation of SYK protein] |
CTD |
PMID:17656488 |
|
NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322
|
|
G |
Cd28 |
Cd28 molecule |
affects response to substance multiple interactions |
ISO |
CD28 protein affects the susceptibility to Mercuric Chloride CD28 protein affects the reaction [Mercuric Chloride results in decreased activity of FBL protein] |
CTD |
PMID:19077085 |
|
NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
|
|
G |
Cd55 |
CD55 molecule (Cromer blood group) |
multiple interactions affects response to substance |
ISO |
[Mercuric Chloride co-treated with CD55] results in increased expression of IFNG mRNA; [Mercuric Chloride co-treated with CD55] results in increased expression of IL10 mRNA; CD55 affects the reaction [Mercuric Chloride results in increased expression of IL10 mRNA]; CD55 affects the reaction [Mercuric Chloride results in increased expression of IL4 mRNA] CD55 protein affects the susceptibility to Mercuric Chloride |
CTD |
PMID:20408894 |
|
NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
|
|
G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CD86 protein |
CTD |
PMID:20417223 PMID:20457211 |
|
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
|
|
G |
Cdc42 |
cell division cycle 42 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CDC42 protein |
CTD |
PMID:22223485 |
|
NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
|
|
G |
Cdca2 |
cell division cycle associated 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of CDCA2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
|
|
G |
Cdh2 |
cadherin 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CDH2 mRNA |
CTD |
PMID:21126564 |
|
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
|
|
G |
Cdh5 |
cadherin 5 |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein] |
CTD |
PMID:31404653 |
|
NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CDK1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
|
|
G |
Cdk14 |
cyclin-dependent kinase 14 |
increases expression decreases expression |
ISO |
Mercuric Chloride results in increased expression of CDK14 mRNA Mercuric Chloride results in decreased expression of CDK14 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861
|
|
G |
Cdk20 |
cyclin-dependent kinase 20 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CDK20 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826
|
|
G |
Cdkl1 |
cyclin dependent kinase like 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CDKL1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CDKN1A mRNA |
CTD |
PMID:16507785 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
|
|
G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CDKN2B mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
|
|
G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions decreases expression |
ISO |
Mercuric Chloride results in decreased expression of and results in decreased activity of CEBPA protein Mercuric Chloride results in decreased expression of CEBPA mRNA |
CTD |
PMID:11267658 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
|
|
G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions increases stability |
ISO |
Mercuric Chloride results in increased expression of and results in increased activity of CEBPB protein Mercuric Chloride results in increased stability of CEBPB mRNA |
CTD |
PMID:11267658 |
|
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
|
|
G |
Cebpd |
CCAAT/enhancer binding protein delta |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CEBPD mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
|
|
G |
Celf2 |
CUGBP, Elav-like family member 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of CELF2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333
|
|
G |
Cep128 |
centrosomal protein 128 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CEP128 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 6:109,951,009...110,328,686
Ensembl chr 6:109,951,061...110,328,713
|
|
G |
Cep68 |
centrosomal protein 68 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CEP68 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr14:94,447,973...94,470,533
Ensembl chr14:94,449,055...94,470,517
|
|
G |
Cfb |
complement factor B |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CFB mRNA |
CTD |
PMID:22136142 |
|
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
|
|
G |
Cfd |
complement factor D |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of CFD mRNA |
CTD |
PMID:22136142 |
|
NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
|
|
G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CHAC1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
|
|
G |
Chd3 |
chromodomain helicase DNA binding protein 3 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CHD3 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047
|
|
G |
Chd7 |
chromodomain helicase DNA binding protein 7 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CHD7 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:21,812,007...21,995,358
Ensembl chr 5:21,812,070...21,995,358
|
|
G |
Chka |
choline kinase alpha |
increases expression affects expression |
EXP ISO |
Mercuric Chloride results in increased expression of CHKA mRNA Mercuric Chloride affects the expression of CHKA mRNA |
CTD |
PMID:16507785 PMID:24118919 |
|
NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
|
|
G |
Chkb |
choline kinase beta |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CHKB mRNA |
CTD |
PMID:24118919 |
|
NCBI chr 7:120,500,960...120,504,359
Ensembl chr 7:120,500,984...120,504,461
|
|
G |
Chordc1 |
cysteine and histidine rich domain containing 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CHORDC1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
|
|
G |
Chrna3 |
cholinergic receptor nicotinic alpha 3 subunit |
multiple interactions |
EXP |
[Mercuric Chloride co-treated with Acetylcholine] affects the activity of [CHRNA3 protein binds to CHRNB4 protein] |
CTD |
PMID:12130716 |
|
NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165
|
|
G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions |
EXP |
[Mercuric Chloride co-treated with Acetylcholine] affects the activity of [CHRNA4 protein binds to CHRNB2 protein]; [Mercuric Chloride co-treated with Acetylcholine] affects the activity of [CHRNA4 protein binds to CHRNB4 protein] |
CTD |
PMID:12130716 |
|
NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
|
|
G |
Chrnb1 |
cholinergic receptor nicotinic beta 1 subunit |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [AGRN protein results in increased phosphorylation of CHRNB1 protein] |
CTD |
PMID:15045580 |
|
NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
|
|
G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
EXP |
[Mercuric Chloride co-treated with Acetylcholine] affects the activity of [CHRNA4 protein binds to CHRNB2 protein] |
CTD |
PMID:12130716 |
|
NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
|
|
G |
Chrnb4 |
cholinergic receptor nicotinic beta 4 subunit |
multiple interactions |
EXP |
[Mercuric Chloride co-treated with Acetylcholine] affects the activity of [CHRNA3 protein binds to CHRNB4 protein]; [Mercuric Chloride co-treated with Acetylcholine] affects the activity of [CHRNA4 protein binds to CHRNB4 protein] |
CTD |
PMID:12130716 |
|
NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027
|
|
G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
increases phosphorylation multiple interactions |
ISO |
Mercuric Chloride results in increased phosphorylation of CHUK protein Mercuric Chloride inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] |
CTD |
PMID:10820281 PMID:21373768 |
|
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
|
|
G |
Cibar1 |
CBY1 interacting BAR domain containing 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of CIBAR1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 5:25,613,993...25,632,440
Ensembl chr 5:25,614,033...25,632,489
|
|
G |
Cimip2a |
ciliary microtubule inner protein 2A |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CIMIP2A mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 3:8,030,548...8,038,370
Ensembl chr 3:8,033,246...8,037,961
|
|
G |
Clic4 |
chloride intracellular channel 4 |
decreases activity |
ISO |
Mercuric Chloride results in decreased activity of CLIC4 protein |
CTD |
PMID:10968996 |
|
NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
|
|
G |
Clip3 |
CAP-GLY domain containing linker protein 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CLIP3 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:85,547,206...85,563,184
|
|
G |
Clu |
clusterin |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CLU mRNA |
CTD |
PMID:16507785 |
|
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
|
|
G |
Clvs2 |
clavesin 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of CLVS2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:23,735,660...23,842,685
Ensembl chr 1:23,735,272...23,842,692
|
|
G |
Cntf |
ciliary neurotrophic factor |
multiple interactions decreases activity |
ISO |
Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]; Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]; Glutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Glutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]; Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]; Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]; Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT1 protein]; Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]; Thioctic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT1 protein]]; Thioctic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]]; Thioctic Acid inhibits the reaction [Mercuric Chloride results in decreased activity of CNTF protein] |
CTD |
PMID:16896058 PMID:19635391 |
|
NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
increases expression |
EXP |
Mercuric Chloride results in increased expression of COL1A1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
|
|
G |
Col4a4 |
collagen type IV alpha 4 chain |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of COL4A4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876
|
|
G |
Crat |
carnitine O-acetyltransferase |
decreases activity |
EXP |
Mercuric Chloride results in decreased activity of CRAT protein |
CTD |
PMID:8075222 |
|
NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
|
|
G |
Crem |
cAMP responsive element modulator |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CREM mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
|
|
G |
Crocc |
ciliary rootlet coiled-coil, rootletin |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CROCC mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:153,320,962...153,363,734
Ensembl chr 5:153,320,962...153,363,578
|
|
G |
Crtap |
cartilage associated protein |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CRTAP mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631
|
|
G |
Csf2 |
colony stimulating factor 2 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CSF2 protein |
CTD |
PMID:21984480 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
|
|
G |
Csf3 |
colony stimulating factor 3 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CSF3 protein |
CTD |
PMID:21984480 |
|
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
|
|
G |
Csmd1 |
CUB and Sushi multiple domains 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CSMD1 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
|
|
G |
Csrnp1 |
cysteine and serine rich nuclear protein 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CSRNP1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
|
|
G |
Csrp3 |
cysteine and glycine rich protein 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CSRP3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
|
|
G |
Cth |
cystathionine gamma-lyase |
decreases activity multiple interactions |
EXP |
Mercuric Chloride results in decreased activity of CTH protein [Mercuric Chloride co-treated with Cysteine] results in decreased activity of CTH protein |
CTD |
PMID:22093698 |
|
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
|
|
G |
Ctsb |
cathepsin B |
increases activity |
ISO |
Mercuric Chloride results in increased activity of CTSB protein |
CTD |
PMID:25237059 |
|
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
|
|
G |
Ctsc |
cathepsin C |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CTSC mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
|
|
G |
Cwc27 |
CWC27 spliceosome associated cyclophilin |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of CWC27 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:35,764,674...35,975,908
Ensembl chr 2:35,764,686...35,975,872
|
|
G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases response to substance increases expression |
EXP |
CXCL10 protein results in increased susceptibility to Mercuric Chloride Mercuric Chloride results in increased expression of CXCL10 mRNA |
CTD |
PMID:12834626 |
|
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
|
|
G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CXCL2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
|
|
G |
Cxcr3 |
C-X-C motif chemokine receptor 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of CXCR3 mRNA; Mercuric Chloride results in increased expression of CXCR3 protein |
CTD |
PMID:12834626 |
|
NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969
|
|
G |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions increases expression |
EXP |
Peptides inhibits the reaction [Mercuric Chloride results in increased expression of CYBA mRNA] |
CTD |
PMID:28987480 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions decreases stability decreases activity increases expression |
ISO |
Hemin inhibits the reaction [Mercuric Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]; HMOX1 mRNA affects the reaction [Mercuric Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]; Mercuric Chloride inhibits the reaction [benz(a)anthracene results in increased activity of CYP1A1 protein]; Mercuric Chloride inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; Mercuric Chloride inhibits the reaction [benzo(b)fluoranthene results in increased activity of CYP1A1 protein]; Mercuric Chloride inhibits the reaction [benzo(k)fluoranthene results in increased activity of CYP1A1 protein]; Mercuric Chloride inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; Mercuric Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Mercuric Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Mercuric Chloride promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1A1 protein]; tin mesoporphyrin inhibits the reaction [Mercuric Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]] Mercuric Chloride results in decreased stability of CYP1A1 protein Mercuric Chloride results in decreased activity of CYP1A1 protein Mercuric Chloride results in increased expression of CYP1A1 mRNA |
CTD |
PMID:11162773 PMID:11408366 PMID:17889500 PMID:20837117 PMID:21435368 PMID:24472606 More...
|
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
|
|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases activity decreases expression |
ISO |
Mercuric Chloride results in decreased activity of CYP1A2 protein Mercuric Chloride results in decreased expression of CYP1A2 protein |
CTD |
PMID:11162773 PMID:37172713 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CYP1B1 mRNA |
CTD |
PMID:21435368 PMID:24472606 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
|
|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CYP2B10 mRNA |
CTD |
PMID:24472606 |
|
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
|
|
G |
Cyp2c6 |
cytochrome P450, family 2, subfamily C, polypeptide 6 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CYP2C29 mRNA |
CTD |
PMID:24472606 |
|
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression increases expression |
EXP ISO |
Mercuric Chloride results in decreased expression of CYP2E1 mRNA Mercuric Chloride results in increased expression of CYP2E1 protein |
CTD |
PMID:22792809 PMID:37172713 |
|
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
|
|
G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CYP3A5 mRNA |
CTD |
PMID:37172713 |
|
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
|
|
G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CYP4F18 mRNA |
CTD |
PMID:24472606 |
|
NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
|
|
G |
Cyp4f6 |
cytochrome P450, family 4, subfamily f, polypeptide 6 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of CYP4F16 mRNA |
CTD |
PMID:24472606 |
|
NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
|
|
G |
Dbp |
D-box binding PAR bZIP transcription factor |
increases expression |
EXP |
Mercuric Chloride results in increased expression of DBP mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
|
|
G |
Dbt |
dihydrolipoamide branched chain transacylase E2 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DBT mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609
|
|
G |
Dcaf12l2 |
DDB1 and CUL4 associated factor 12-like 2 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DCAF12L2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr X:123,293,761...123,296,550
Ensembl chr X:123,294,744...123,296,156
|
|
G |
Dcaf8 |
DDB1 and CUL4 associated factor 8 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of DCAF8 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726
|
|
G |
Dcn |
decorin |
increases expression |
EXP |
Mercuric Chloride results in increased expression of DCN mRNA; Mercuric Chloride results in increased expression of DCN protein |
CTD |
PMID:16005714 |
|
NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
EXP ISO |
Mercuric Chloride results in increased expression of DDIT3 mRNA Mercuric Chloride results in increased expression of DDIT3 protein 4-phenylbutyric acid inhibits the reaction [Mercuric Chloride results in increased expression of DDIT3 protein] |
CTD |
PMID:30807803 PMID:32879258 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
|
|
G |
Dgkg |
diacylglycerol kinase, gamma |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of DGKG mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
|
|
G |
Dglucy |
D-glutamate cyclase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of DGLUCY mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 6:120,055,480...120,130,910
Ensembl chr 6:120,055,460...120,130,910
|
|
G |
Dixdc1 |
DIX domain containing 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of DIXDC1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090
|
|
G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of DNAJB4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
|
|
G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of DNAJB9 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
|
|
G |
Dock10 |
dedicator of cytokinesis 10 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of DOCK10 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
|
|
G |
Dock11 |
dedicator of cytokinesis 11 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of DOCK11 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr X:115,131,720...115,314,854
Ensembl chr X:115,131,909...115,314,854
|
|
G |
Dusp5 |
dual specificity phosphatase 5 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of DUSP5 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
|
|
G |
Dusp7 |
dual specificity phosphatase 7 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of DUSP7 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404
|
|
G |
Dusp8 |
dual specificity phosphatase 8 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of DUSP8 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
|
|
G |
Ebf2 |
EBF transcription factor 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of EBF2 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr15:41,435,509...41,634,403
Ensembl chr15:41,435,509...41,634,403
|
|
G |
Edn1 |
endothelin 1 |
multiple interactions increases expression |
EXP |
candesartan cilexetil inhibits the reaction [Mercuric Chloride results in increased expression of EDN1 mRNA]; pimagedine inhibits the reaction [Mercuric Chloride results in increased expression of EDN1 mRNA] Mercuric Chloride results in increased expression of EDN1 mRNA; Mercuric Chloride results in increased expression of EDN1 protein |
CTD |
PMID:9788586 PMID:9853001 |
|
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
|
|
G |
Eef1g |
eukaryotic translation elongation factor 1 gamma |
multiple interactions |
ISO |
Mercuric Chloride results in increased expression of and results in increased secretion of EEF1G protein |
CTD |
PMID:24980261 |
|
NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
|
|
G |
Egf |
epidermal growth factor |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of EGF mRNA |
CTD |
PMID:8538927 PMID:10901180 |
|
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
|
|
G |
Egfr |
epidermal growth factor receptor |
increases expression |
EXP ISO |
Mercuric Chloride results in increased expression of EGFR mRNA |
CTD |
PMID:10901180 PMID:37172713 |
|
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
|
|
G |
Egr1 |
early growth response 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of EGR1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
|
|
G |
Ehbp1 |
EH domain binding protein 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of EHBP1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr14:96,093,327...96,380,502
Ensembl chr14:96,093,327...96,345,332
|
|
G |
Ehd1 |
EH-domain containing 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of EHD1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212
|
|
G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of EHHADH mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
|
|
G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [[IFNB1 results in increased expression of EIF2AK2 protein] which results in decreased susceptibility to Mercuric Chloride]; [IFNB1 results in increased expression of EIF2AK2 protein] which results in decreased susceptibility to Mercuric Chloride |
CTD |
PMID:16324719 |
|
NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
|
|
G |
Elovl3 |
ELOVL fatty acid elongase 3 |
decreases response to substance increases expression |
ISO |
ELOVL3 protein results in decreased susceptibility to Mercuric Chloride Mercuric Chloride results in increased expression of ELOVL3 mRNA |
CTD |
PMID:24118919 |
|
NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
|
|
G |
Elovl6 |
ELOVL fatty acid elongase 6 |
increases response to substance affects expression |
ISO |
ELOVL6 protein results in increased susceptibility to Mercuric Chloride Mercuric Chloride affects the expression of ELOVL6 mRNA |
CTD |
PMID:24118919 |
|
NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
|
|
G |
Eno1 |
enolase 1 |
multiple interactions |
ISO |
Mercuric Chloride results in increased expression of and results in increased secretion of ENO1 protein |
CTD |
PMID:26259607 |
|
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 Ensembl chr 3:160,719,951...160,731,336
|
|
G |
Entpd5 |
ectonucleoside triphosphate diphosphohydrolase 5 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ENTPD5 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530
|
|
G |
Epb41l3 |
erythrocyte membrane protein band 4.1-like 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of EPB41L3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607
|
|
G |
Ephx1 |
epoxide hydrolase 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of EPHX1 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
|
|
G |
Ephx2 |
epoxide hydrolase 2 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased expression of and results in increased activity of EPHX2 protein] which results in decreased abundance of 11,12-epoxy-5,8,14-eicosatrienoic acid; [Mercuric Chloride results in increased expression of and results in increased activity of EPHX2 protein] which results in decreased abundance of 14,15-epoxy-5,8,11-eicosatrienoic acid; Mercuric Chloride results in increased expression of and results in increased activity of EPHX2 protein |
CTD |
PMID:24472606 |
|
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
|
|
G |
Epo |
erythropoietin |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [cobaltous chloride results in increased expression of EPO mRNA]; Mercuric Chloride inhibits the reaction [cobaltous chloride results in increased expression of EPO protein]; Mercuric Chloride inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA]; Mercuric Chloride inhibits the reaction [Oxygen deficiency results in increased expression of EPO protein] |
CTD |
PMID:11090055 |
|
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
|
|
G |
Esr1 |
estrogen receptor 1 |
decreases expression affects response to substance multiple interactions increases activity |
ISO |
Mercuric Chloride results in decreased expression of ESR1 mRNA; Mercuric Chloride results in decreased expression of ESR1 protein ESR1 protein affects the susceptibility to Mercuric Chloride Mercuric Chloride inhibits the reaction [Estradiol binds to ESR1 protein] Mercuric Chloride results in increased activity of ESR1 protein |
CTD |
PMID:12746304 PMID:17716812 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
|
|
G |
Etv2 |
ETS variant transcription factor 2 |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Mercuric Chloride inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
|
NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431
|
|
G |
Etv4 |
ETS variant transcription factor 4 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ETV4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
|
|
G |
Evi5 |
ecotropic viral integration site 5 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of EVI5 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678
|
|
G |
F3 |
coagulation factor III, tissue factor |
multiple interactions increases activity |
ISO |
ANXA5 protein inhibits the reaction [Mercuric Chloride results in increased activity of F3 protein] |
CTD |
PMID:17726162 |
|
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
|
|
G |
Fabp6 |
fatty acid binding protein 6 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of FABP6 mRNA |
CTD |
PMID:31175882 |
|
NCBI chr10:28,063,603...28,068,276
Ensembl chr10:28,063,603...28,068,282
|
|
G |
Fadd |
Fas associated via death domain |
increases expression multiple interactions |
ISO |
Mercuric Chloride results in increased expression of FADD protein [Mercuric Chloride co-treated with sodium arsenite co-treated with Cadmium Chloride] results in increased expression of FADD protein |
CTD |
PMID:16421179 |
|
NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
|
|
G |
Fads1 |
fatty acid desaturase 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of FADS1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
|
|
G |
Fam135a |
family with sequence similarity 135, member A |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of FAM135A mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 9:26,420,116...26,500,803
Ensembl chr 9:26,420,528...26,500,717
|
|
G |
Fam169a |
family with sequence similarity 169, member A |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of FAM169A mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 2:28,384,162...28,441,361
Ensembl chr 2:28,383,784...28,438,910
|
|
G |
Fam219a |
family with sequence similarity 219, member A |
increases expression |
EXP |
Mercuric Chloride results in increased expression of FAM219A mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:56,679,272...56,729,959
Ensembl chr 5:56,680,613...56,729,924
|
|
G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
ISO |
Mercuric Chloride inhibits the reaction [FAS affects the activity of CASP3 protein] [Mercuric Chloride co-treated with sodium arsenite co-treated with Cadmium Chloride] results in increased expression of FAS protein Mercuric Chloride results in increased expression of FAS protein |
CTD |
PMID:15585371 PMID:16421179 |
|
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
|
|
G |
Fbl |
fibrillarin |
affects localization multiple interactions increases cleavage decreases activity |
ISO |
Mercuric Chloride affects the localization of FBL protein CD28 protein affects the reaction [Mercuric Chloride results in decreased activity of FBL protein]; IFNG protein affects the reaction [Mercuric Chloride results in decreased activity of FBL protein]; IL4 protein affects the reaction [Mercuric Chloride results in decreased activity of FBL protein]; IL6 protein affects the reaction [Mercuric Chloride results in decreased activity of FBL protein] Mercuric Chloride results in increased cleavage of FBL protein |
CTD |
PMID:10925315 PMID:10942594 PMID:12388758 PMID:19077085 |
|
NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
|
|
G |
Fcer2 |
Fc epsilon receptor II |
affects expression increases expression |
EXP |
Mercuric Chloride affects the expression of FCER2 protein [Mercuric Chloride results in increased expression of IL4 protein] which results in increased expression of FCER2 protein |
CTD |
PMID:7657819 |
|
NCBI chr12:1,742,809...1,754,476
Ensembl chr12:1,742,815...1,754,476
|
|
G |
Fcgr1a |
Fc gamma receptor 1A |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA] |
CTD |
PMID:28453771 |
|
NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
|
|
G |
Fcgr2a |
Fc gamma receptor 2A |
affects response to substance affects binding |
ISO |
FCGR3 protein affects the susceptibility to Mercuric Chloride Mercuric Chloride binds to FCGR3 protein |
CTD |
PMID:10666595 PMID:18314309 |
|
NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
|
|
G |
Fcgr2b |
Fc gamma receptor 2B |
affects response to substance |
ISO |
FCGR2B protein affects the susceptibility to Mercuric Chloride |
CTD |
PMID:18314309 |
|
NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
|
|
G |
Fkbp1a |
FKBP prolyl isomerase 1A |
increases expression |
EXP |
Mercuric Chloride results in increased expression of FKBP1A mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
|
|
G |
Fn1 |
fibronectin 1 |
affects folding affects binding increases expression |
EXP |
Mercuric Chloride affects the folding of FN1 protein Mercuric Chloride binds to FN1 protein Mercuric Chloride results in increased expression of FN1 protein |
CTD |
PMID:10469268 PMID:11768240 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
|
|
G |
Fn3k |
fructosamine 3 kinase |
increases expression |
EXP |
Mercuric Chloride results in increased expression of FN3K mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:106,700,670...106,715,903
Ensembl chr10:106,700,670...106,715,895
|
|
G |
Fnbp4 |
formin binding protein 4 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of FNBP4 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 3:76,733,012...76,763,077
Ensembl chr 3:76,733,027...76,763,079
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP ISO |
Mercuric Chloride promotes the reaction [HSPA5 protein binds to FOS enhancer] Mercuric Chloride results in increased expression of FOS mRNA |
CTD |
PMID:10362023 PMID:15111246 PMID:16507785 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
|
|
G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
EXP |
Mercuric Chloride results in increased expression of FOSL1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
|
|
G |
Fsd1l |
fibronectin type III and SPRY domain containing 1-like |
increases expression |
EXP |
Mercuric Chloride results in increased expression of FSD1L mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 5:68,258,877...68,334,931
Ensembl chr 5:68,258,932...68,334,928
|
|
G |
Ftl1 |
ferritin light chain 1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of FTL mRNA |
CTD |
PMID:38568856 |
|
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725 Ensembl chr 2:95,936,387...95,939,725
|
|
G |
G3bp1 |
G3BP stress granule assembly factor 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of G3BP1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268
|
|
G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
decreases expression decreases activity increases activity multiple interactions |
EXP |
Mercuric Chloride results in decreased expression of G6PC1 mRNA Mercuric Chloride results in decreased activity of G6PC1 protein Mercuric Chloride results in increased activity of G6PC1 protein zinc chloride inhibits the reaction [Mercuric Chloride results in increased activity of G6PC1 protein] |
CTD |
PMID:16507785 PMID:22413763 PMID:22416658 |
|
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
increases activity |
EXP |
Mercuric Chloride results in increased activity of G6PD protein |
CTD |
PMID:15977196 |
|
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
|
|
G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of GABBR2 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
|
|
G |
Gabrb3 |
gamma-aminobutyric acid type A receptor subunit beta 3 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRB3 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
|
|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
EXP |
Mercuric Chloride results in increased expression of GADD45A mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
|
|
G |
Galnt11 |
polypeptide N-acetylgalactosaminyltransferase 11 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of GALNT11 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140
|
|
G |
Gar1 |
GAR1 ribonucleoprotein |
increases expression |
EXP |
Mercuric Chloride results in increased expression of GAR1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524
|
|
G |
Gata2 |
GATA binding protein 2 |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Mercuric Chloride inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
|
NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
|
|
G |
Gatm |
glycine amidinotransferase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of GATM mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression decreases response to substance multiple interactions |
ISO EXP |
Mercuric Chloride results in increased expression of GCLC mRNA GCLC protein results in decreased susceptibility to Mercuric Chloride [Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of GCLC protein [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein] |
CTD |
PMID:24118919 PMID:27837179 PMID:30359721 PMID:38568856 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions increases expression |
ISO |
ABCC2 gene mutant form promotes the reaction [Mercuric Chloride results in increased expression of GCLM mRNA] [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA |
CTD |
PMID:24039982 PMID:27188386 |
|
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
|
|
G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of GDF15 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
|
|
G |
Gemin4 |
gem (nuclear organelle) associated protein 4 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of GEMIN4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431 Ensembl chr10:61,066,425...61,073,431
|
|
G |
Ggt1 |
gamma-glutamyltransferase 1 |
multiple interactions increases expression |
EXP |
Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]; Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]]; Selenium inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]] |
CTD |
PMID:24485406 |
|
NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
|
|
G |
Gja1 |
gap junction protein, alpha 1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of GJA1 mRNA; Mercuric Chloride results in increased expression of GJA1 protein |
CTD |
PMID:18409822 |
|
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
|
|
G |
Gjb1 |
gap junction protein, beta 1 |
increases expression decreases expression |
ISO EXP |
Mercuric Chloride results in increased expression of GJB1 mRNA; Mercuric Chloride results in increased expression of GJB1 protein Mercuric Chloride results in decreased expression of GJB1 mRNA |
CTD |
PMID:16507785 PMID:18409822 |
|
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
|
|
G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of GJB2 mRNA; Mercuric Chloride results in increased expression of GJB2 protein |
CTD |
PMID:18409822 |
|
NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
|
|
G |
Gldc |
glycine decarboxylase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of GLDC mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097
|
|
G |
Glrx |
glutaredoxin |
affects metabolic processing |
ISO |
Mercuric Chloride affects the metabolism of GLRX protein |
CTD |
PMID:18321861 |
|
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
|
|
G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of GPAT3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
|
|
G |
Gpnmb |
glycoprotein nmb |
increases expression |
EXP |
Mercuric Chloride results in increased expression of GPNMB mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions decreases activity increases activity increases expression |
EXP ISO |
Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]; Berberine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]; Plant Extracts inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]; Selenium inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]] Mercuric Chloride results in decreased activity of GPT protein Mercuric Chloride results in increased expression of GPT protein |
CTD |
PMID:24485406 PMID:24751971 PMID:24954677 PMID:26215012 PMID:33476711 PMID:37172713 More...
|
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions decreases expression |
EXP |
Berberine inhibits the reaction [Mercuric Chloride results in decreased expression of GPX1 mRNA] |
CTD |
PMID:24751971 PMID:33460233 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
|
|
G |
Gramd1b |
GRAM domain containing 1B |
increases expression |
EXP |
Mercuric Chloride results in increased expression of GRAMD1B mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:40,654,492...40,893,869
Ensembl chr 8:40,659,182...40,893,925
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
GSK3B protein promotes the reaction [Mercuric Chloride results in increased activity of BAX protein]; GSK3B protein promotes the reaction [Mercuric Chloride results in increased cleavage of CASP3 protein] |
CTD |
PMID:22785175 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
|
|
G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases activity |
ISO EXP |
naringin inhibits the reaction [Mercuric Chloride results in decreased activity of GSR protein] Berberine inhibits the reaction [Mercuric Chloride results in decreased activity of GSR protein]; Plant Extracts inhibits the reaction [Mercuric Chloride results in decreased activity of GSR protein] |
CTD |
PMID:23650045 PMID:24751971 PMID:25600690 PMID:26215012 PMID:33460233 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
increases expression multiple interactions |
ISO |
Mercuric Chloride results in increased expression of GSTM1 protein [Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of GSTM1 protein |
CTD |
PMID:9434069 PMID:30359721 |
|
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
affects response to substance multiple interactions increases expression |
ISO EXP |
GSTP1 protein SNP affects the susceptibility to Mercuric Chloride Mercuric Chloride inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene] Mercuric Chloride results in increased expression of GSTP1 mRNA [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GSTP1 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GSTP1 protein |
CTD |
PMID:22401947 PMID:29298499 PMID:32599119 |
|
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
|
|
G |
Hacd2 |
3-hydroxyacyl-CoA dehydratase 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of HACD2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
EXP ISO |
Mercuric Chloride results in increased expression of HAVCR1 mRNA; Mercuric Chloride results in increased expression of HAVCR1 protein |
CTD |
PMID:18441258 PMID:21126564 PMID:25145654 PMID:27720909 PMID:28536007 PMID:32599119 More...
|
|
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
|
|
G |
Hbegf |
heparin-binding EGF-like growth factor |
increases expression |
EXP |
Mercuric Chloride results in increased expression of HBEGF mRNA; Mercuric Chloride results in increased expression of HBEGF protein |
CTD |
PMID:7635938 PMID:10901180 |
|
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
|
|
G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
multiple interactions increases activity |
ISO |
Mercuric Chloride promotes the reaction [HCK protein results in increased phosphorylation of CBL protein] Mercuric Chloride results in increased activity of HCK protein |
CTD |
PMID:10092522 PMID:14551197 |
|
NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
|
|
G |
Hectd1 |
HECT domain E3 ubiquitin protein ligase 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of HECTD1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 6:69,181,429...69,268,045
Ensembl chr 6:69,181,436...69,268,053
|
|
G |
Hgf |
hepatocyte growth factor |
increases activity increases expression |
EXP |
Mercuric Chloride results in increased activity of HGF protein Mercuric Chloride results in increased expression of HGF mRNA |
CTD |
PMID:8342615 |
|
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
|
|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases activity multiple interactions |
ISO |
Mercuric Chloride results in increased activity of HIF1A protein Mercuric Chloride inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]; Mercuric Chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein] |
CTD |
PMID:11090055 PMID:19502547 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
|
|
G |
Hk2 |
hexokinase 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of HK2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
|
|
G |
Hmbs |
hydroxymethylbilane synthase |
decreases activity |
EXP |
Mercury dichloride decreases activity of purified Hmbs protein |
RGD |
PMID:6732900 |
RGD:25394584 |
NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
EXP |
Mercuric Chloride results in increased expression of HMGCR mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
|
|
G |
Hmmr |
hyaluronan-mediated motility receptor |
increases expression |
EXP |
Mercuric Chloride results in increased expression of HMMR mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression affects expression |
ISO EXP |
[Mercuric Chloride co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA; HMOX1 mRNA affects the reaction [Mercuric Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]; Mercuric Chloride promotes the reaction [HSF1 protein binds to HMOX1 promoter] Mercuric Chloride results in increased expression of HMOX1 mRNA Mercuric Chloride affects the expression of HMOX1 mRNA Mercuric Chloride results in increased expression of HMOX1 mRNA; Mercuric Chloride results in increased expression of HMOX1 protein HMOX1 enhancer affects the reaction [Mercuric Chloride results in increased expression of HMOX1 mRNA] [lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased expression of HMOX1 protein; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 protein; [zinc chloride co-treated with Sodium Selenite] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased expression of HMOX1 protein]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 protein]; Sodium Selenite inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased expression of HMOX1 protein] |
CTD |
PMID:7538129 PMID:8612205 PMID:8872981 PMID:9544699 PMID:9863766 PMID:16507785 PMID:17244614 PMID:20713136 PMID:20837117 PMID:21435368 PMID:22954530 PMID:27837179 PMID:28536007 PMID:36646412 More...
|
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
|
|
G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
EXP |
Mercuric Chloride promotes the reaction [HSPA5 protein binds to HRAS enhancer] |
CTD |
PMID:15111246 |
|
NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
|
|
G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of HSD11B2 protein |
CTD |
PMID:16189294 |
|
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
|
|
G |
Hsd17b2 |
hydroxysteroid (17-beta) dehydrogenase 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of HSD17B2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
|
|
G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
multiple interactions decreases expression |
EXP |
alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of HSD17B3 mRNA] |
CTD |
PMID:32134168 |
|
NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
|
|
G |
Hsd3b2 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
multiple interactions decreases expression |
EXP |
alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of HSD3B2 mRNA] |
CTD |
PMID:32134168 |
|
NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
|
|
G |
Hsf1 |
heat shock transcription factor 1 |
multiple interactions increases activity |
ISO |
Mercuric Chloride promotes the reaction [HSF1 protein binds to HMOX1 promoter]; Mercuric Chloride promotes the reaction [HSF1 protein binds to HSPA1A promoter] Mercuric Chloride results in increased activity of HSF1 protein |
CTD |
PMID:17244614 |
|
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
|
|
G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of HSP90B1 protein |
CTD |
PMID:10696793 |
|
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
|
|
G |
Hspa12a |
heat shock protein family A (Hsp70) member 12A |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of HSPA12A mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
|
|
G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
multiple interactions increases expression |
ISO EXP |
[Mercuric Chloride results in increased abundance of Reactive Oxygen Species] which results in increased expression of HSPA1A mRNA; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of HSPA1A mRNA]; Mercuric Chloride promotes the reaction [HSF1 protein binds to HSPA1A promoter]; Selenomethionine inhibits the reaction [Mercuric Chloride results in increased expression of HSPA1A mRNA] |
CTD |
PMID:16324719 PMID:16507785 PMID:17244614 |
|
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
|
|
G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
increases expression |
EXP |
Mercuric Chloride results in increased expression of HSPA1B mRNA |
CTD |
PMID:16507785 |
|
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
|
|
G |
Hspa4l |
heat shock protein family A (Hsp70) member 4 like |
increases expression |
EXP |
Mercuric Chloride results in increased expression of HSPA4L mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions affects expression increases expression |
EXP ISO |
Cycloheximide inhibits the reaction [Mercuric Chloride results in increased expression of HSPA5 protein]; Dactinomycin inhibits the reaction [Mercuric Chloride results in increased expression of HSPA5 mRNA]; Mercuric Chloride promotes the reaction [HSPA5 protein binds to FOS enhancer]; Mercuric Chloride promotes the reaction [HSPA5 protein binds to HRAS enhancer]; Mercuric Chloride results in increased expression of and results in increased activity of HSPA5 protein Mercuric Chloride affects the expression of HSPA5 mRNA Mercuric Chloride results in increased expression of HSPA5 mRNA; Mercuric Chloride results in increased expression of HSPA5 protein 4-phenylbutyric acid inhibits the reaction [Mercuric Chloride results in increased expression of HSPA5 protein] |
CTD |
PMID:15111246 PMID:17915553 PMID:30807803 PMID:32879258 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
|
|
G |
Hspa6l-ps1 |
heat shock protein family A (Hsp70) member 6 like, pseudogene 1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of HSPA6 mRNA |
CTD |
PMID:15287566 |
|
NCBI chr13:83,273,176...83,274,317
|
|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions |
ISO |
Mercuric Chloride results in increased expression of and results in increased secretion of HSPA8 protein |
CTD |
PMID:26259607 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
|
|
G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions increases expression |
EXP |
[Mercuric Chloride co-treated with bimoclomol] affects the localization of HSPA9 protein; Melatonin affects the reaction [Mercuric Chloride results in increased expression of HSPA9 protein] |
CTD |
PMID:15375764 PMID:16801527 PMID:16891066 PMID:21616119 |
|
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
|
|
G |
Hspb1 |
heat shock protein family B (small) member 1 |
decreases response to substance |
EXP |
HSPB1 protein results in decreased susceptibility to Mercuric Chloride |
CTD |
PMID:8917706 |
|
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
|
|
G |
Hspb8 |
heat shock protein family B (small) member 8 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of HSPB8 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
|
|
G |
Iars1 |
isoleucyl-tRNA synthetase 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IARS1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO EXP |
Mercuric Chloride results in increased expression of ICAM1 mRNA; Mercuric Chloride results in increased expression of ICAM1 protein |
CTD |
PMID:11884233 PMID:22822941 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
|
|
G |
Ier2 |
immediate early response 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IER2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
|
|
G |
Ifi44 |
interferon-induced protein 44 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFI44 mRNA |
CTD |
PMID:28453771 |
|
NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
|
|
G |
Ifnb1 |
interferon beta 1 |
multiple interactions |
ISO |
2-Aminopurine inhibits the reaction [[IFNB1 results in increased expression of EIF2AK2 protein] which results in decreased susceptibility to Mercuric Chloride]; [IFNB1 results in increased expression of EIF2AK2 protein] which results in decreased susceptibility to Mercuric Chloride |
CTD |
PMID:16324719 |
|
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
|
|
G |
Ifng |
interferon gamma |
multiple interactions decreases activity affects response to substance decreases expression increases secretion increases expression |
ISO EXP |
[Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Glutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Mercuric Chloride inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; Mercuric Chloride promotes the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] Mercuric Chloride results in decreased activity of IFNG protein IFNG protein affects the susceptibility to Mercuric Chloride Mercuric Chloride results in decreased expression of IFNG protein Mercuric Chloride results in increased secretion of IFNG protein Mercuric Chloride results in increased expression of IFNG mRNA; Mercuric Chloride results in increased expression of IFNG protein [Mercuric Chloride co-treated with CD55] results in increased expression of IFNG mRNA; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG protein; [Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of IFNG protein; B2M protein affects the reaction [Mercuric Chloride results in increased expression of IFNG mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IFNG protein affects the reaction [Mercuric Chloride results in decreased activity of FBL protein]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG mRNA]; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercuric Chloride results in increased expression of IFNG mRNA] |
CTD |
PMID:7657819 PMID:8898950 PMID:9376071 PMID:10447925 PMID:15588918 PMID:16428073 PMID:16896058 PMID:19077085 PMID:19203382 PMID:19462287 PMID:19635391 PMID:20049214 PMID:20408894 PMID:21084432 PMID:21793797 PMID:21984480 PMID:25237059 PMID:28453771 PMID:29594315 More...
|
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Ifrd1 |
interferon-related developmental regulator 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IFRD1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
|
|
G |
Igf1 |
insulin-like growth factor 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of IGF1 mRNA |
CTD |
PMID:7540432 PMID:8538927 |
|
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
|
|
G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IGFBP1 mRNA |
CTD |
PMID:7540432 |
|
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
|
|
G |
Ighg1 |
immunoglobulin heavy constant gamma 1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of IGHG1 protein |
CTD |
PMID:17015760 |
|
Ensembl chr 6:132,389,370...132,393,397
|
|
G |
Il10 |
interleukin 10 |
multiple interactions increases secretion increases expression decreases expression |
ISO EXP |
Mercuric Chloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] Mercuric Chloride results in increased secretion of IL10 protein Mercuric Chloride results in increased expression of IL10 mRNA; Mercuric Chloride results in increased expression of IL10 protein [Mercuric Chloride co-treated with CD55] results in increased expression of IL10 mRNA; CD55 affects the reaction [Mercuric Chloride results in increased expression of IL10 mRNA] Mercuric Chloride results in decreased expression of IL10 protein Selenium affects the reaction [Mercuric Chloride results in decreased expression of IL10 protein] |
CTD |
PMID:8898950 PMID:12490134 PMID:20049214 PMID:20408894 PMID:21984480 PMID:26089086 More...
|
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
|
|
G |
Il12a |
interleukin 12A |
multiple interactions |
ISO |
Mercuric Chloride results in increased expression of [IL12A protein binds to IL12B protein] |
CTD |
PMID:21984480 |
|
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
|
|
G |
Il12b |
interleukin 12B |
decreases expression multiple interactions |
ISO |
Mercuric Chloride results in decreased expression of IL12B protein Mercuric Chloride results in increased expression of [IL12A protein binds to IL12B protein] Mercuric Chloride inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein] |
CTD |
PMID:21984480 PMID:36416909 |
|
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
|
|
G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
decreases expression increases expression |
EXP |
Mercuric Chloride results in decreased expression of IL12RB2 mRNA Mercuric Chloride results in increased expression of IL12RB2 mRNA |
CTD |
PMID:10447925 PMID:10651948 |
|
NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289
|
|
G |
Il13 |
interleukin 13 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of IL13 protein |
CTD |
PMID:21984480 |
|
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
|
|
G |
Il17a |
interleukin 17A |
increases expression |
ISO |
Mercuric Chloride results in increased expression of IL-17A protein |
CTD |
PMID:21984480 |
|
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
|
|
G |
Il1a |
interleukin 1 alpha |
increases expression |
ISO |
Mercuric Chloride results in increased expression of IL1A protein |
CTD |
PMID:21984480 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions decreases expression increases expression affects expression affects secretion |
EXP ISO |
Tretinoin inhibits the reaction [Mercuric Chloride results in increased expression of IL1B mRNA] Mercuric Chloride results in decreased expression of IL1B protein Mercuric Chloride inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Mercuric Chloride inhibits the reaction [Uric Acid results in increased secretion of IL1B protein]; Mercuric Chloride promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL1B mRNA; [Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of IL1B mRNA; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercuric Chloride results in increased expression of IL1B mRNA] Mercuric Chloride results in increased expression of IL1B mRNA; Mercuric Chloride results in increased expression of IL1B protein Mercuric Chloride results in decreased expression of IL1B mRNA Mercuric Chloride analog affects the expression of IL1B mRNA Mercuric Chloride affects the secretion of IL1B protein; Mercuric Chloride analog affects the secretion of IL1B protein |
CTD |
PMID:9138684 PMID:16507785 PMID:17250768 PMID:20049214 PMID:21051542 PMID:21084432 PMID:21984480 PMID:25237059 PMID:28453771 PMID:29594315 PMID:29981841 PMID:37172713 PMID:38568856 More...
|
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
|
G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1RN protein] |
CTD |
PMID:20049214 |
|
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
|
|
G |
Il2 |
interleukin 2 |
decreases expression increases expression multiple interactions decreases activity decreases secretion |
ISO EXP |
Mercuric Chloride results in decreased expression of IL2 protein Mercuric Chloride results in increased expression of IL2 protein Mercuric Chloride results in increased expression of IL2 mRNA Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of IL2 protein]; Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]; Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein] Mercuric Chloride results in decreased secretion of IL2 protein |
CTD |
PMID:8898950 PMID:9376071 PMID:16428073 PMID:21984480 PMID:22910795 PMID:27714827 More...
|
|
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
|
|
G |
Il20 |
interleukin 20 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IL20 mRNA; Mercuric Chloride results in increased expression of IL20 protein |
CTD |
PMID:18496552 |
|
NCBI chr13:42,380,981...42,384,625
Ensembl chr13:42,380,981...42,384,625
|
|
G |
Il20ra |
interleukin 20 receptor subunit alpha |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IL20RA mRNA |
CTD |
PMID:18496552 |
|
NCBI chr 1:14,424,215...14,494,226
Ensembl chr 1:14,451,228...14,493,602
|
|
G |
Il20rb |
interleukin 20 receptor subunit beta |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IL20RB mRNA |
CTD |
PMID:18496552 |
|
NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942
|
|
G |
Il22ra1 |
interleukin 22 receptor subunit alpha 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IL22RA1 mRNA |
CTD |
PMID:18496552 |
|
NCBI chr 5:147,961,496...147,986,296
Ensembl chr 5:147,961,349...147,986,296
|
|
G |
Il2ra |
interleukin 2 receptor subunit alpha |
increases expression |
ISO |
Mercuric Chloride results in increased expression of IL2RA protein |
CTD |
PMID:7867075 |
|
NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
|
|
G |
Il4 |
interleukin 4 |
multiple interactions increases secretion increases activity increases expression affects response to substance decreases expression increases response to substance |
ISO EXP |
Mercuric Chloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL4 protein] Mercuric Chloride results in increased secretion of IL4 protein Deferoxamine inhibits the reaction [Mercuric Chloride results in increased expression of IL4 mRNA]; Levamisole inhibits the reaction [Mercuric Chloride results in increased expression of IL4 mRNA]; Pyruvic Acid inhibits the reaction [Mercuric Chloride results in increased expression of IL4 mRNA]; S-ethyl glutathione inhibits the reaction [Mercuric Chloride results in increased expression of IL4 mRNA]; S-ethyl glutathione inhibits the reaction [Mercuric Chloride results in increased expression of IL4 protein] Mercuric Chloride results in increased activity of IL4 promoter IL4 protein affects the susceptibility to Mercuric Chloride [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA; B2M protein affects the reaction [Mercuric Chloride results in increased expression of IL4 mRNA]; CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; CD55 affects the reaction [Mercuric Chloride results in increased expression of IL4 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IL4 protein affects the reaction [Mercuric Chloride results in decreased activity of FBL protein]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA] [Mercuric Chloride results in increased expression of IL4 protein] which results in increased expression of FCER2 protein; Mercuric Chloride results in increased expression of IL4; Mercuric Chloride results in increased expression of IL4 mRNA; Mercuric Chloride results in increased expression of IL4 protein Mercuric Chloride results in decreased expression of IL4 mRNA IL4 protein results in increased susceptibility to Mercuric Chloride |
CTD |
PMID:7589090 PMID:7657819 PMID:7664789 PMID:7867075 PMID:7871386 PMID:8102566 PMID:8560497 PMID:8898950 PMID:9182889 PMID:9376071 PMID:9405450 PMID:9647229 PMID:10886234 PMID:10886398 PMID:11222498 PMID:12490134 PMID:12849721 PMID:18075863 PMID:18432732 PMID:19077085 PMID:19604304 PMID:20049214 PMID:20408894 PMID:21793797 PMID:22136142 PMID:24089704 PMID:28453771 More...
|
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
|
|
G |
Il5 |
interleukin 5 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of IL5 protein |
CTD |
PMID:21984480 |
|
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
|
|
G |
Il6 |
interleukin 6 |
decreases activity multiple interactions affects response to substance increases secretion increases expression decreases expression |
ISO EXP |
Mercuric Chloride results in decreased activity of IL6 protein [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL6 mRNA; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IL6 protein affects the reaction [Mercuric Chloride results in decreased activity of FBL protein]; Mercuric Chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA] Mercuric Chloride promotes the reaction [TAC1 protein results in increased secretion of IL6 protein] IL6 protein affects the susceptibility to Mercuric Chloride Mercuric Chloride results in increased secretion of IL6 protein Mercuric Chloride results in increased expression of IL6 protein Mercuric Chloride results in increased expression of IL6 mRNA; Mercuric Chloride results in increased expression of IL6 protein Mercuric Chloride results in decreased expression of IL6 protein [lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of IL6 protein; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of IL6 protein]; Selenium affects the reaction [Mercuric Chloride results in decreased expression of IL6 protein]; Sodium Selenite promotes the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of IL6 protein]; zinc chloride inhibits the reaction [Sodium Selenite promotes the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of IL6 protein]] |
CTD |
PMID:8898950 PMID:12175822 PMID:16428073 PMID:19077085 PMID:19635391 PMID:20222982 PMID:21628964 PMID:25458486 PMID:26089086 PMID:28453771 PMID:32134168 PMID:36646412 PMID:37172713 More...
|
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
|
|
G |
Ins1 |
insulin 1 |
decreases expression multiple interactions decreases secretion |
EXP ISO |
Mercuric Chloride results in decreased expression of INS1 protein [Mercuric Chloride results in increased abundance of Mercury] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased secretion of INS1 protein] |
CTD |
PMID:20006636 PMID:30807803 PMID:33038468 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
|
|
G |
Insyn1 |
inhibitory synaptic factor 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of INSYN1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:58,904,153...58,914,850
Ensembl chr 8:58,904,153...58,914,843
|
|
G |
Ipo5 |
importin 5 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IPO5 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126
|
|
G |
Ipp |
intracisternal A particle-promoted polypeptide |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of IPP mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:129,962,528...130,001,237
Ensembl chr 5:129,962,643...130,001,242
|
|
G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA] |
CTD |
PMID:28453771 |
|
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
|
|
G |
Irf2bp2 |
interferon regulatory factor 2 binding protein 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of IRF2BP2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642
|
|
G |
Irf8 |
interferon regulatory factor 8 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA] |
CTD |
PMID:28453771 |
|
NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
|
|
G |
Irs2 |
insulin receptor substrate 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of IRS2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
|
|
G |
Itga4 |
integrin subunit alpha 4 |
increases expression multiple interactions |
EXP |
Mercuric Chloride results in increased expression of ITGA4 protein Tretinoin inhibits the reaction [Mercuric Chloride results in increased expression of ITGA4 mRNA] |
CTD |
PMID:17250768 |
|
NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
|
|
G |
Itprid2 |
ITPR interacting domain containing 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ITPRID2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978
|
|
G |
Itsn2 |
intersectin 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ITSN2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 6:27,616,645...27,727,373
Ensembl chr 6:27,600,406...27,727,124
|
|
G |
Jag1 |
jagged canonical Notch ligand 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of JAG1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
|
|
G |
Jak1 |
Janus kinase 1 |
decreases phosphorylation |
ISO |
Mercuric Chloride results in decreased phosphorylation of JAK1 protein |
CTD |
PMID:16896058 PMID:19635391 |
|
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
|
|
G |
Jak2 |
Janus kinase 2 |
decreases phosphorylation |
ISO |
Mercuric Chloride results in decreased phosphorylation of JAK2 protein |
CTD |
PMID:16896058 PMID:19635391 |
|
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
|
|
G |
Jmjd1c |
jumonji domain containing 1C |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of JMJD1C mRNA |
CTD |
PMID:27188386 |
|
NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases phosphorylation increases expression |
ISO EXP |
Mercuric Chloride results in increased phosphorylation of JUN protein Mercuric Chloride results in increased expression of JUN mRNA |
CTD |
PMID:10861847 PMID:16507785 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
|
|
G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
Mercuric Chloride results in increased expression of JUNB mRNA |
CTD |
PMID:16507785 |
|
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
|
|
G |
Kat6a |
lysine acetyltransferase 6A |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of KAT6A mRNA |
CTD |
PMID:27188386 |
|
NCBI chr16:69,084,914...69,165,923
Ensembl chr16:69,084,914...69,163,606
|
|
G |
Kcmf1 |
potassium channel modulatory factor 1 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCMF1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:104,888,452...104,950,234
Ensembl chr 4:104,889,847...104,950,234
|
|
G |
Kcnab1 |
potassium voltage-gated channel subfamily A regulatory beta subunit 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of KCNAB1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
|
|
G |
Kcne1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of KCNE1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
|
|
G |
Kcnj12 |
potassium inwardly-rectifying channel, subfamily J, member 12 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of KCNJ12 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492
|
|
G |
Kcnj15 |
potassium inwardly-rectifying channel, subfamily J, member 15 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of KCNJ15 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952
|
|
G |
Kcnk3 |
potassium two pore domain channel subfamily K member 3 |
decreases expression multiple interactions |
EXP |
Mercuric Chloride results in decreased expression of KCNK3 mRNA Mercuric Chloride results in increased expression of and affects the localization of KCNK3 protein |
CTD |
PMID:19533102 |
|
NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153
|
|
G |
Kctd4 |
potassium channel tetramerization domain containing 4 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of KCTD4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr15:51,263,664...51,278,030
Ensembl chr15:51,274,295...51,277,499
|
|
G |
Kdm6b |
lysine demethylase 6B |
increases expression |
EXP |
Mercuric Chloride results in increased expression of KDM6B mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794
|
|
G |
Kdsr |
3-ketodihydrosphingosine reductase |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KDSR mRNA |
CTD |
PMID:27188386 |
|
NCBI chr13:22,862,117...22,894,118
Ensembl chr13:22,862,117...22,894,108
|
|
G |
Khnyn |
KH and NYN domain containing |
increases expression |
ISO |
Mercuric Chloride results in increased expression of KHNYN protein |
CTD |
PMID:37172713 |
|
NCBI chr15:29,365,399...29,379,650
Ensembl chr15:29,365,260...29,376,967
|
|
G |
Kif3a |
kinesin family member 3a |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of KIF3A mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191
|
|
G |
Kifc1 |
kinesin family member C1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of KIFC1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
|
|
G |
Klf6 |
KLF transcription factor 6 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of KLF6 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
|
|
G |
Klhl28 |
kelch-like family member 28 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of KLHL28 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164
|
|
G |
Klk4 |
kallikrein-related peptidase 4 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of KLK4 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:94,344,195...94,349,425
Ensembl chr 1:94,344,195...94,349,424
|
|
G |
Klrd1 |
killer cell lectin like receptor D1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of KLRD1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
|
|
G |
Kpna4 |
karyopherin subunit alpha 4 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of KPNA4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081
|
|
G |
Krt79 |
keratin 79 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of KRT79 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 7:133,056,710...133,067,750
Ensembl chr 7:133,056,709...133,067,705
|
|
G |
Krtap1-1 |
keratin associated protein 1-1 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KRTAP1-5 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:84,545,765...84,546,331
Ensembl chr10:84,545,580...84,546,354
|
|
G |
Kyat1 |
kynurenine aminotransferase 1 |
multiple interactions increases expression |
ISO EXP |
KYAT1 protein results in increased amination of [Mercuric Chloride co-treated with Cysteine] [Mercuric Chloride co-treated with Cysteine] results in decreased activity of KYAT1 protein Mercuric Chloride results in increased expression of KYAT1 protein |
CTD |
PMID:9765069 PMID:22093698 |
|
NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355
|
|
G |
Kynu |
kynureninase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of KYNU mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
|
|
G |
L2hgdh |
L-2-hydroxyglutarate dehydrogenase |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of L2HGDH mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 6:88,164,429...88,205,585
Ensembl chr 6:88,164,440...88,205,578
|
|
G |
L3hypdh |
trans-L-3-hydroxyproline dehydratase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of L3HYPDH mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 6:90,636,310...90,647,106
Ensembl chr 6:90,636,310...90,647,106
|
|
G |
Lama3 |
laminin subunit alpha 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of LAMA3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353
|
|
G |
Larp4 |
La ribonucleoprotein 4 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LARP4 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 7:131,104,470...131,152,692
Ensembl chr 7:131,101,564...131,150,811
|
|
G |
Lcn2 |
lipocalin 2 |
increases expression decreases secretion |
EXP ISO |
Mercuric Chloride results in increased expression of LCN2 mRNA Mercuric Chloride results in decreased secretion of LCN2 protein |
CTD |
PMID:16507785 PMID:25145654 PMID:27720909 PMID:27888128 PMID:28536007 |
|
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
|
|
G |
Lep |
leptin |
decreases expression decreases secretion increases expression |
ISO EXP |
Mercuric Chloride results in decreased expression of LEP mRNA Mercuric Chloride results in decreased secretion of LEP protein Mercuric Chloride results in increased expression of LEP mRNA |
CTD |
PMID:22019852 PMID:30807803 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
|
|
G |
Lhb |
luteinizing hormone subunit beta |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of LHB protein |
CTD |
PMID:25368988 |
|
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
|
|
G |
Litaf |
lipopolysaccharide-induced TNF factor |
increases expression |
EXP |
Mercuric Chloride results in increased expression of LITAF mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
|
|
G |
Lmnb1 |
lamin B1 |
increases activity |
ISO |
Mercuric Chloride results in increased activity of LMNB1 protein |
CTD |
PMID:12504520 |
|
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
|
|
G |
Lonrf3 |
LON peptidase N-terminal domain and ring finger 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of LONRF3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr X:115,565,214...115,603,886
Ensembl chr X:115,565,267...115,598,809
|
|
G |
Lpgat1 |
lysophosphatidylglycerol acyltransferase 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of LPGAT1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
|
|
G |
Lrp6 |
LDL receptor related protein 6 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of LRP6 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
|
|
G |
Lrp8 |
LDL receptor related protein 8 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of LRP8 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
|
|
G |
Lrrc61 |
leucine rich repeat containing 61 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of LRRC61 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:77,503,882...77,523,909
Ensembl chr 4:77,503,857...77,524,020
|
|
G |
Lst1 |
leukocyte specific transcript 1 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LST1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997
|
|
G |
Ly96 |
lymphocyte antigen 96 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of LY96 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
|
|
G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of MAP2K6 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
|
|
G |
Map3k3 |
mitogen activated protein kinase kinase kinase 3 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of MAP3K3 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
|
|
G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
increases activity |
ISO |
Mercuric Chloride results in increased activity of MAP3K5 protein |
CTD |
PMID:16337887 |
|
NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO EXP |
[2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of [MAPK1 protein co-treated with MAPK3 protein]] which results in decreased susceptibility to Mercuric Chloride; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPK1 protein]; Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Mercuric Chloride analog results in increased phosphorylation of MAPK1 protein]; Mercuric Chloride inhibits the reaction [CD22 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] Mercuric Chloride analog results in increased phosphorylation of MAPK1 protein; Mercuric Chloride results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:10861847 PMID:17656488 PMID:19327394 PMID:20951154 PMID:21373768 PMID:22910795 PMID:23415682 PMID:29981841 More...
|
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
increases phosphorylation |
ISO |
Mercuric Chloride results in increased phosphorylation of MAPK14 protein |
CTD |
PMID:15585369 |
|
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
[2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of [MAPK1 protein co-treated with MAPK3 protein]] which results in decreased susceptibility to Mercuric Chloride; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPK3 protein]; Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Mercuric Chloride analog results in increased phosphorylation of MAPK3 protein]; Mercuric Chloride inhibits the reaction [CD22 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] Mercuric Chloride analog results in increased phosphorylation of MAPK3 protein; Mercuric Chloride results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:10861847 PMID:17656488 PMID:19327394 PMID:20951154 PMID:21373768 PMID:22910795 PMID:23415682 PMID:29981841 More...
|
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mapk4 |
mitogen-activated protein kinase 4 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of MAPK4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr18:67,512,805...67,661,271
Ensembl chr18:67,512,807...67,661,842
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
Mercuric Chloride results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:10861847 PMID:12883084 PMID:21373768 |
|
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
increases phosphorylation |
ISO |
Mercuric Chloride results in increased phosphorylation of MAPK9 protein |
CTD |
PMID:10861847 |
|
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
|
|
G |
Mapt |
microtubule-associated protein tau |
multiple interactions increases phosphorylation |
ISO |
Melatonin inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPT protein]; Mercuric Chloride binds to and affects the folding of MAPT protein; Mercuric Chloride promotes the reaction [Heparin promotes the reaction [MAPT protein binds to MAPT protein]] |
CTD |
PMID:10617124 PMID:20665688 |
|
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
|
|
G |
Mbd4 |
methyl-CpG binding domain 4 DNA glycosylase |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBD4 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982
|
|
G |
Mbl1 |
mannose binding lectin 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of MBL1 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174
|
|
G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of MCL1 mRNA |
CTD |
PMID:23202902 |
|
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
|
|
G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of MDM2 mRNA |
CTD |
PMID:23202902 |
|
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
|
|
G |
Me1 |
malic enzyme 1 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ME1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
|
|
G |
Mef2d |
myocyte enhancer factor 2D |
increases expression |
EXP |
Mercuric Chloride results in increased expression of MEF2D mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457
|
|
G |
Miga1 |
mitoguardin 1 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MIGA1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 2:241,224,118...241,279,174
Ensembl chr 2:241,226,015...241,279,106
|
|
G |
Mmp1 |
matrix metallopeptidase 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of MMP1 mRNA |
CTD |
PMID:11817102 |
|
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of MMP9 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
|
|
G |
Mob1a |
MOB kinase activator 1A |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of MOB1A mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561 Ensembl chr 1:115,831,551...115,848,561
|
|
G |
Mobp |
myelin-associated oligodendrocyte basic protein |
increases expression |
ISO |
Mercuric Chloride results in increased expression of MOBP mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 8:119,869,504...119,899,605
Ensembl chr 8:119,869,626...119,899,563
|
|
G |
Mpst |
mercaptopyruvate sulfurtransferase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of MPST mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141
|
|
G |
Mrs2 |
magnesium transporter MRS2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of MRS2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr17:40,063,924...40,087,073
Ensembl chr17:40,063,962...40,081,887
|
|
G |
Msr1 |
macrophage scavenger receptor 1 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of MSR1 mRNA |
CTD |
PMID:28453771 |
|
NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
|
|
G |
Mt1 |
metallothionein 1 |
increases expression multiple interactions affects expression affects binding decreases expression |
EXP ISO |
Mercuric Chloride results in increased expression of MT1 mRNA; Mercuric Chloride results in increased expression of MT1 protein; Mercuric Chloride results in increased expression of MT1A mRNA Curcumin affects the reaction [Mercuric Chloride results in increased expression of MT1A mRNA]; Vitamin E promotes the reaction [Mercuric Chloride results in increased expression of MT1A mRNA] Mercuric Chloride affects the expression of MT1A mRNA [Zinc binds to MT1 protein] which binds to Mercuric Chloride [MT1 gene mutant form co-treated with MT2 gene mutant form co-treated with Mercuric Chloride] results in decreased abundance of Dopamine; [MT1 gene mutant form co-treated with MT2 gene mutant form] results in increased susceptibility to Mercuric Chloride Mercuric Chloride results in decreased expression of MT1 mRNA |
CTD |
PMID:10991963 PMID:12815612 PMID:15606775 PMID:16507785 PMID:18226494 PMID:19088408 PMID:19720107 PMID:20229497 PMID:21094152 PMID:21435368 PMID:21628964 PMID:21787585 PMID:28536007 More...
|
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
|
|
G |
Mt2A |
metallothionein 2A |
multiple interactions increases expression affects expression |
ISO EXP |
Mercuric Chloride inhibits the reaction [Lipopolysaccharides results in increased expression of MT2A mRNA] Mercuric Chloride results in increased expression of MT2A mRNA Curcumin affects the reaction [Mercuric Chloride results in increased expression of MT2A mRNA] Mercuric Chloride affects the expression of MT2A mRNA [MT1 gene mutant form co-treated with MT2 gene mutant form co-treated with Mercuric Chloride] results in decreased abundance of Dopamine; [MT1 gene mutant form co-treated with MT2 gene mutant form] results in increased susceptibility to Mercuric Chloride Mercuric Chloride results in increased expression of MT2 mRNA |
CTD |
PMID:9138684 PMID:10362023 PMID:10991963 PMID:18226494 PMID:20229497 PMID:20450053 PMID:21628964 More...
|
|
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
|
|
G |
Mt3 |
metallothionein 3 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of MT3 mRNA |
CTD |
PMID:21628964 |
|
NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
|
|
G |
Mta2 |
metastasis associated 1 family, member 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of MTA2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:205,838,181...205,846,903
Ensembl chr 1:205,837,964...205,846,946
|
|
G |
Mthfd1l |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like |
increases expression |
EXP |
Mercuric Chloride results in increased expression of MTHFD1L mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905
|
|
G |
Mthfd2 |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
increases expression |
EXP |
Mercuric Chloride results in increased expression of MTHFD2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
|
|
G |
Mtpap |
mitochondrial poly(A) polymerase |
increases expression |
ISO |
Mercuric Chloride results in increased expression of MTPAP mRNA |
CTD |
PMID:27188386 |
|
NCBI chr17:53,320,739...53,341,500
Ensembl chr17:53,320,741...53,341,538
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression |
EXP |
Mercuric Chloride results in increased expression of MYC mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
|
|
G |
Myh10 |
myosin heavy chain 10 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of MYH10 protein |
CTD |
PMID:37172713 |
|
NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,394,389...53,525,165
|
|
G |
Mylk3 |
myosin light chain kinase 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of MYLK3 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954
|
|
G |
Myo5a |
myosin VA |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of MYO5A mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
|
|
G |
Naa16 |
N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of NAA16 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr15:54,711,620...54,770,915
Ensembl chr15:54,711,621...54,770,896
|
|
G |
Naalad2 |
N-acetylated alpha-linked acidic dipeptidase 2 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NAALAD2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 8:15,406,119...15,479,714
Ensembl chr 8:15,407,043...15,479,714
|
|
G |
Ncbp1 |
nuclear cap binding protein subunit 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of NCBP1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089
|
|
G |
Ndnf |
neuron-derived neurotrophic factor |
increases expression |
EXP |
Mercuric Chloride results in increased expression of NDNF mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 4:94,944,392...94,981,871
Ensembl chr 4:94,944,360...94,981,873
|
|
G |
Ndrg3 |
NDRG family member 3 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NDRG3 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 3:145,587,505...145,650,896
Ensembl chr 3:145,548,041...145,650,873 Ensembl chr 3:145,548,041...145,650,873
|
|
G |
Nefm |
neurofilament medium chain |
increases expression |
EXP |
Mercuric Chloride results in increased expression of NEFM mRNA |
CTD |
PMID:16507785 |
|
NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
|
|
G |
Neurl2 |
neuralized E3 ubiquitin protein ligase 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of NEURL2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:153,566,659...153,569,380
Ensembl chr 3:153,566,660...153,569,380
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions affects response to substance increases expression decreases expression affects localization |
ISO EXP |
[Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of NFE2L2 protein; Acetylcysteine inhibits the reaction [Mercuric Chloride promotes the reaction [Lipopolysaccharides results in increased expression of NFE2L2 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of NFE2L2 protein]; Mercuric Chloride affects the localization of and results in increased stability of NFE2L2 protein; Mercuric Chloride promotes the reaction [Lipopolysaccharides results in increased expression of NFE2L2 protein]; NFE2L2 mRNA affects the reaction [Mercuric Chloride results in increased activity of NQO1 protein]; NFE2L2 mRNA affects the reaction [Mercuric Chloride results in increased expression of NQO1 mRNA]; sodium selenide inhibits the reaction [Mercuric Chloride promotes the reaction [Lipopolysaccharides results in increased expression of NFE2L2 protein]]; sodium selenide inhibits the reaction [Mercuric Chloride results in increased expression of NFE2L2 protein]; Sodium Selenite affects the reaction [Mercuric Chloride affects the localization of NFE2L2 protein] [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Mercuric Chloride Mercuric Chloride results in decreased expression of NFE2L2 mRNA [lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of NFE2L2 protein; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 protein; [Sodium Selenite co-treated with zinc chloride] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of NFE2L2 protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of NFE2L2 protein]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 protein] |
CTD |
PMID:17959236 PMID:19303893 PMID:21843634 PMID:23202902 PMID:24816296 PMID:27837179 PMID:30359721 PMID:32134168 PMID:36646412 More...
|
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
|
|
G |
Nfia |
nuclear factor I/A |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of NFIA mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO EXP |
Mercuric Chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased activity of [RELA protein binds to NFKB1 protein]]; Mercuric Chloride inhibits the reaction [TNF results in increased activity of [RELA protein binds to NFKB1 protein]] |
CTD |
PMID:12426138 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
increases degradation |
ISO |
Mercuric Chloride results in increased degradation of NFKBIA protein |
CTD |
PMID:21373768 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
|
|
G |
Nipsnap1 |
nipsnap homolog 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of NIPSNAP1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098
|
|
G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions increases expression |
ISO |
N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercuric Chloride results in increased expression of NLRP3 mRNA] |
CTD |
PMID:25237059 |
|
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
|
|
G |
Nme4 |
NME/NM23 nucleoside diphosphate kinase 4 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of NME4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:15,114,624...15,118,479
Ensembl chr10:15,002,926...15,118,479
|
|
G |
Nog |
noggin |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AMACR mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BICDL1 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CHD3 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCMF1 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KRTAP1-5 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LST1 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPATA6L mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TPSG1 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C1ORF53 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CEP128 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DBT mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DCAF12L2 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRB3 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KDSR mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of L2HGDH mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LARP4 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBD4 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ME1 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MIGA1 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NAALAD2 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NDRG3 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NQO1 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIAS2 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIR mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF32 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFXN5 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLA2 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC30A5 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VIRMA mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of XIAP mRNA; [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZNF814 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
|
|
G |
Nop58 |
NOP58 ribonucleoprotein |
increases expression |
EXP |
Mercuric Chloride results in increased expression of NOP58 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810
|
|
G |
Nos1 |
nitric oxide synthase 1 |
decreases expression decreases phosphorylation |
EXP |
Mercuric Chloride results in decreased expression of NOS1 mRNA; Mercuric Chloride results in decreased expression of NOS1 protein Mercuric Chloride results in decreased phosphorylation of NOS1 protein |
CTD |
PMID:12460744 PMID:21554244 |
|
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression affects expression |
ISO EXP |
[Dimercaprol co-treated with Mercuric Chloride] inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]; Mercuric Chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of NOS2 mRNA]; Mercuric Chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of NOS2 protein]; Mercuric Chloride inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein] Mercuric Chloride results in increased expression of NOS2 mRNA Mercuric Chloride results in increased expression of NOS2 mRNA; Mercuric Chloride results in increased expression of NOS2 protein candesartan cilexetil inhibits the reaction [Mercuric Chloride results in increased expression of NOS2 mRNA]; Melatonin affects the reaction [Mercuric Chloride results in increased expression of NOS2 protein]; pimagedine inhibits the reaction [Mercuric Chloride results in increased expression of NOS2 mRNA]; pimagedine inhibits the reaction [Mercuric Chloride results in increased expression of NOS2 protein] Mercuric Chloride analog affects the expression of NOS2 mRNA |
CTD |
PMID:9810145 PMID:9853001 PMID:12175822 PMID:16801527 PMID:18441258 PMID:18838692 PMID:19501138 PMID:22822941 PMID:29981841 More...
|
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
|
|
G |
Nos3 |
nitric oxide synthase 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of NOS3 mRNA; Mercuric Chloride results in decreased expression of NOS3 protein |
CTD |
PMID:9788586 PMID:9853001 |
|
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
|
|
G |
Nox1 |
NADPH oxidase 1 |
multiple interactions increases expression decreases expression |
EXP |
celecoxib inhibits the reaction [Mercuric Chloride results in increased expression of NOX1 mRNA]; rofecoxib inhibits the reaction [Mercuric Chloride results in increased expression of NOX1 mRNA]; SB 203580 inhibits the reaction [Mercuric Chloride results in increased expression of NOX1 mRNA]; U 0126 inhibits the reaction [Mercuric Chloride results in increased expression of NOX1 mRNA] Mercuric Chloride results in decreased expression of NOX1 protein |
CTD |
PMID:21232032 PMID:23415682 PMID:28987480 |
|
NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
|
|
G |
Nox4 |
NADPH oxidase 4 |
increases expression multiple interactions |
EXP ISO |
Mercuric Chloride results in increased expression of NOX4 mRNA Peptides inhibits the reaction [Mercuric Chloride results in increased expression of NOX4 mRNA] [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NOX4 protein |
CTD |
PMID:21232032 PMID:28987480 PMID:30359721 |
|
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
|
|
G |
Nphs1 |
NPHS1 adhesion molecule, nephrin |
decreases expression multiple interactions |
EXP |
Mercuric Chloride results in decreased expression of NPHS1 mRNA Mercuric Chloride promotes the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein]; Puromycin Aminonucleoside promotes the reaction [Mercuric Chloride results in decreased expression of NPHS1 mRNA] |
CTD |
PMID:11012881 |
|
NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078
|
|
G |
Nploc4 |
NPL4 homolog, ubiquitin recognition factor |
increases expression |
EXP |
Mercuric Chloride results in increased expression of NPL4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913
|
|
G |
Nppa |
natriuretic peptide A |
increases expression |
ISO |
Mercuric Chloride results in increased expression of NPPA mRNA |
CTD |
PMID:24472606 |
|
NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
|
|
G |
Nppb |
natriuretic peptide B |
increases expression |
ISO |
Mercuric Chloride results in increased expression of NPPB mRNA |
CTD |
PMID:24472606 |
|
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
|
|
G |
Npy1r |
neuropeptide Y receptor Y1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of NPY1R mRNA |
CTD |
PMID:16507785 |
|
NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions increases activity decreases expression increases expression |
ISO |
[Dimercaprol co-treated with Mercuric Chloride] results in increased activity of NQO1 protein Mercuric Chloride results in increased activity of NQO1 protein [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NQO1 mRNA; Mercuric Chloride promotes the reaction [sulforaphane results in increased expression of and results in increased activity of NQO1 protein]; Mercuric Chloride promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Mercuric Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein]; Mercuric Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Mercuric Chloride results in increased expression of and results in increased activity of NQO1 protein; NFE2L2 mRNA affects the reaction [Mercuric Chloride results in increased activity of NQO1 protein]; NFE2L2 mRNA affects the reaction [Mercuric Chloride results in increased expression of NQO1 mRNA] Mercuric Chloride results in decreased expression of NQO1 mRNA; Mercuric Chloride results in decreased expression of NQO1 protein |
CTD |
PMID:18838692 PMID:21843634 PMID:23202902 PMID:26272509 PMID:27188386 PMID:37172713 PMID:38568856 More...
|
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
|
|
G |
Nr1d2 |
nuclear receptor subfamily 1, group D, member 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of NR1D2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
|
|
G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of NR1I2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Mercuric Chloride inhibits the reaction [Triamcinolone Acetonide binds to NR3C1 protein]]; Mercuric Chloride inhibits the reaction [Triamcinolone Acetonide binds to NR3C1 protein] |
CTD |
PMID:15250541 |
|
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
|
|
G |
Nt5e |
5' nucleotidase, ecto |
decreases activity |
EXP |
Mercuric Chloride results in decreased activity of NT5E protein |
CTD |
PMID:22416658 |
|
NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
|
|
G |
Ntf3 |
neurotrophin 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of NTF3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
|
|
G |
Nudt16l1 |
nudix hydrolase 16 like 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of NUDT16L1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:10,636,174...10,638,090
Ensembl chr10:10,636,174...10,688,370
|
|
G |
Odf2 |
outer dense fiber of sperm tails 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of ODF2 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 3:13,160,981...13,207,223
Ensembl chr 3:13,161,494...13,206,985
|
|
G |
Olfml1 |
olfactomedin-like 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of OLFML1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:161,478,129...161,502,541
Ensembl chr 1:161,478,242...161,502,537
|
|
G |
Ormdl1 |
ORMDL sphingolipid biosynthesis regulator 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of ORMDL1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211
|
|
G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of OSGIN1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
|
|
G |
Osr1 |
odd-skipped related transcription factor 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of OSR1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817
|
|
G |
P2rx2 |
purinergic receptor P2X 2 |
multiple interactions |
EXP |
Mercuric Chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein] |
CTD |
PMID:16190872 |
|
NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
|
|
G |
P4ha1 |
prolyl 4-hydroxylase subunit alpha 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of P4HA1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
|
|
G |
Parg |
poly (ADP-ribose) glycohydrolase |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of PARG mRNA |
CTD |
PMID:24118919 |
|
NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO |
Mercuric Chloride results in increased cleavage of PARP1 protein [Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein; Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein] |
CTD |
PMID:11068922 PMID:12504520 PMID:12505371 PMID:22909951 |
|
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
|
|
G |
Patj |
PATJ, crumbs cell polarity complex component |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of PATJ mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 5:113,061,985...113,364,807
Ensembl chr 5:113,062,118...113,364,807
|
|
G |
Pcnp |
PEST proteolytic signal containing nuclear protein |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of PCNP mRNA |
CTD |
PMID:27188386 |
|
NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348
|
|
G |
Pcsk6 |
proprotein convertase subtilisin/kexin type 6 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of PCSK6 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
|
|
G |
Pcsk9 |
proprotein convertase subtilisin/kexin type 9 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of PCSK9 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
|
|
G |
Pdk2 |
pyruvate dehydrogenase kinase 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of PDK2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
|
|
G |
Pdzd2 |
PDZ domain containing 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of PDZD2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:61,384,614...61,770,516
Ensembl chr 2:61,386,381...61,770,524
|
|
G |
Pdzd7 |
PDZ domain containing 7 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of PDZD7 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:243,888,295...243,907,778
Ensembl chr 1:243,888,281...243,906,839
|
|
G |
Pdzd8 |
PDZ domain containing 8 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PDZD8 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:258,449,218...258,506,828
Ensembl chr 1:258,449,218...258,506,828
|
|
G |
Pfkfb3 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PFKFB3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
|
|
G |
Pgr |
progesterone receptor |
multiple interactions increases expression |
ISO |
Estradiol promotes the reaction [Mercuric Chloride results in increased expression of PGR mRNA]; Estradiol promotes the reaction [Mercuric Chloride results in increased expression of PGR protein]; fulvestrant inhibits the reaction [Mercuric Chloride results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [Mercuric Chloride results in increased expression of PGR protein]; Mercuric Chloride promotes the reaction [Estradiol results in increased expression of PGR mRNA]; Mercuric Chloride promotes the reaction [Estradiol results in increased expression of PGR protein] Mercuric Chloride results in increased expression of PGR mRNA; Mercuric Chloride results in increased expression of PGR protein |
CTD |
PMID:12746304 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
|
|
G |
Pias2 |
protein inhibitor of activated STAT, 2 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIAS2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033
|
|
G |
Pip4p2 |
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PIP4P2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:28,259,821...28,307,225
Ensembl chr 5:28,259,760...28,307,225
|
|
G |
Pir |
pirin |
increases expression multiple interactions |
ISO |
Mercuric Chloride results in increased expression of PIR mRNA [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIR mRNA |
CTD |
PMID:27188386 |
|
NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218
|
|
G |
Pkm |
pyruvate kinase M1/2 |
multiple interactions |
ISO |
Mercuric Chloride results in increased expression of and results in increased secretion of PKM protein |
CTD |
PMID:24980261 |
|
NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
|
|
G |
Plekha5 |
pleckstrin homology domain containing A5 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of PLEKHA5 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:173,333,891...173,503,546
Ensembl chr 4:173,334,055...173,503,546
|
|
G |
Plk2 |
polo-like kinase 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PLK2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
|
|
G |
Pln |
phospholamban |
decreases phosphorylation increases expression |
EXP |
Mercuric Chloride results in decreased phosphorylation of PLN protein Mercuric Chloride results in increased expression of PLN protein |
CTD |
PMID:21723307 |
|
NCBI chr20:32,629,537...32,639,559
|
|
G |
Pm20d2 |
peptidase M20 domain containing 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of PM20D2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:47,566,059...47,586,334
Ensembl chr 5:47,566,072...47,586,212
|
|
G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of PMAIP1 mRNA |
CTD |
PMID:20713136 |
|
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
|
|
G |
Pnkd |
PNKD metallo-beta-lactamase domain containing |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of PNKD mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124
|
|
G |
Ppan |
peter pan homolog |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PPAN mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:19,423,908...19,427,941
Ensembl chr 8:19,423,961...19,427,938
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
decreases expression increases expression |
ISO EXP |
Mercuric Chloride results in decreased expression of PPARA mRNA Mercuric Chloride results in increased expression of PPARA mRNA |
CTD |
PMID:22019852 PMID:30807803 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression increases expression |
ISO EXP |
Mercuric Chloride results in decreased expression of PPARG mRNA; Mercuric Chloride results in decreased expression of PPARG protein Mercuric Chloride results in increased expression of PPARG mRNA |
CTD |
PMID:12883084 PMID:22019852 PMID:30807803 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
|
|
G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PPP1R15A mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
|
|
G |
Pprc1 |
PPARG related coactivator 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PPRC1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587
|
|
G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PRKAA1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
|
|
G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of PRKAA2 mRNA |
CTD |
PMID:22019852 |
|
NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
|
|
G |
Prkrip1 |
PRKR interacting protein 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of PRKRIP1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr12:20,470,802...20,491,789
Ensembl chr12:20,470,820...20,489,115
|
|
G |
Prph |
peripherin |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PRPH mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136
|
|
G |
Pten |
phosphatase and tensin homolog |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of PTEN mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
|
|
G |
Ptges3 |
prostaglandin E synthase 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PTGES3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
|
|
G |
Ptgr1 |
prostaglandin reductase 1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of PTGR1 mRNA |
CTD |
PMID:38568856 |
|
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA]; U 0126 inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA] Mercuric Chloride results in increased expression of PTGS2 mRNA; Mercuric Chloride results in increased expression of PTGS2 protein |
CTD |
PMID:20228412 PMID:23415682 PMID:28987480 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
|
|
G |
Pth1r |
parathyroid hormone 1 receptor |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of PTH1R mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
|
|
G |
Pthlh |
parathyroid hormone-like hormone |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PTHLH mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
|
|
G |
Ptp4a1 |
protein tyrosine phosphatase 4A1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PTP4A1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
|
|
G |
Ptpn12 |
protein tyrosine phosphatase, non-receptor type 12 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of PTPN12 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:14,020,997...14,092,931
Ensembl chr 4:14,021,052...14,092,927
|
|
G |
Pvr |
PVR cell adhesion molecule |
increases expression |
EXP |
Mercuric Chloride results in increased expression of PVR mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
|
|
G |
Rab11fip3 |
RAB11 family interacting protein 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of RAB11FIP3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479
|
|
G |
Rab2a |
RAB2A, member RAS oncogene family |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of RAB2A mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 5:21,676,017...21,740,035
Ensembl chr 5:21,676,129...21,739,899
|
|
G |
Rac1 |
Rac family small GTPase 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of RAC1 protein |
CTD |
PMID:22223485 |
|
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
|
|
G |
Ranbp1 |
RAN binding protein 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of RANBP1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
|
|
G |
Rapgef1 |
Rap guanine nucleotide exchange factor 1 |
increases phosphorylation |
ISO |
Mercuric Chloride results in increased phosphorylation of RAPGEF1 protein |
CTD |
PMID:14551197 |
|
NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984
|
|
G |
Rbak |
RB-associated KRAB zinc finger |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of RBAK mRNA |
CTD |
PMID:27188386 |
|
NCBI chr12:11,375,314...11,388,937
Ensembl chr12:11,375,318...11,388,934
|
|
G |
Rbm15 |
RNA binding motif protein 15 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of RBM15 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703
|
|
G |
Rbm39 |
RNA binding motif protein 39 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of RBM39 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213
|
|
G |
Rc3h2 |
ring finger and CCCH-type domains 2 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of RC3H2 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO EXP |
Mercuric Chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of RELA protein] Mercuric Chloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased activity of [RELA protein binds to NFKB1 protein]]; Mercuric Chloride inhibits the reaction [TNF results in increased activity of [RELA protein binds to NFKB1 protein]] |
CTD |
PMID:12175822 PMID:12426138 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
|
|
G |
Rfx4 |
regulatory factor X4 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of RFX4 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 7:18,853,065...19,015,378
Ensembl chr 7:18,853,322...19,014,967
|
|
G |
Rhoa |
ras homolog family member A |
decreases response to substance |
EXP |
RHOA protein results in decreased susceptibility to Mercuric Chloride |
CTD |
PMID:22223485 |
|
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
|
|
G |
Riok3 |
RIO kinase 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of RIOK3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343
|
|
G |
Rnd3 |
Rho family GTPase 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of RND3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
|
|
G |
Rnf32 |
ring finger protein 32 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF32 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:6,144,749...6,209,320
Ensembl chr 4:6,149,841...6,209,257
|
|
G |
Rpgr |
retinitis pigmentosa GTPase regulator |
affects response to substance |
ISO |
RPGR gene SNP affects the susceptibility to Mercuric Chloride |
CTD |
PMID:25622337 |
|
NCBI chr X:12,566,447...12,628,171
Ensembl chr X:12,566,645...12,747,882
|
|
G |
Rrp12 |
ribosomal RNA processing 12 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of RRP12 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:240,672,378...240,705,992
Ensembl chr 1:240,672,382...240,706,018
|
|
G |
Rsad2 |
radical S-adenosyl methionine domain containing 2 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of RSAD2 mRNA |
CTD |
PMID:28453771 |
|
NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
|
|
G |
RT1-Ba |
RT1 class II, locus Ba |
increases expression |
EXP |
Mercuric Chloride results in increased expression of RT1-BA protein |
CTD |
PMID:9536116 |
|
NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
|
|
G |
RT1-Da |
RT1 class II, locus Da |
increases expression |
EXP |
Mercuric Chloride results in increased expression of RT1-DA protein |
CTD |
PMID:9536116 |
|
NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
|
|
G |
Rxrg |
retinoid X receptor gamma |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of RXRG mRNA |
CTD |
PMID:16507785 |
|
NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
|
|
G |
Ryr2 |
ryanodine receptor 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of RYR2 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
|
|
G |
S100a8 |
S100 calcium binding protein A8 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of S100A8 mRNA |
CTD |
PMID:38568856 |
|
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
|
|
G |
S100a9 |
S100 calcium binding protein A9 |
increases expression decreases expression |
EXP ISO |
Mercuric Chloride results in increased expression of S100A9 mRNA Mercuric Chloride results in decreased expression of S100A9 mRNA |
CTD |
PMID:16507785 PMID:38568856 |
|
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
|
|
G |
Sars1 |
seryl-tRNA synthetase 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SARS1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
|
|
G |
Scnn1a |
sodium channel epithelial 1 subunit alpha |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SCNN1A protein |
CTD |
PMID:16189294 |
|
NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
|
|
G |
Scnn1b |
sodium channel epithelial 1 subunit beta |
affects expression |
EXP |
Mercuric Chloride affects the expression of SCNN1B protein |
CTD |
PMID:16189294 |
|
NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451
|
|
G |
Scnn1g |
sodium channel epithelial 1 subunit gamma |
affects expression |
EXP |
Mercuric Chloride affects the expression of SCNN1G protein |
CTD |
PMID:16189294 |
|
NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816
|
|
G |
Sdcbp |
syndecan binding protein |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SDCBP mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
|
|
G |
Sel1l |
SEL1L adaptor subunit of SYVN1 ubiquitin ligase |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SEL1L mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648
|
|
G |
Selenow |
selenoprotein W |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SELENOW mRNA |
CTD |
PMID:27188386 PMID:38568856 |
|
NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724 Ensembl chr 1:76,598,779...76,604,724
|
|
G |
Serpine1 |
serpin family E member 1 |
increases expression multiple interactions |
EXP ISO |
Mercuric Chloride results in increased expression of SERPINE1 mRNA; Mercuric Chloride results in increased expression of SERPINE1 protein Tacrolimus inhibits the reaction [Mercuric Chloride results in increased expression of SERPINE1 protein] |
CTD |
PMID:11817102 PMID:14620542 PMID:38568856 |
|
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
|
|
G |
Sesn1 |
sestrin 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SESN1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
|
|
G |
Setx |
senataxin |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SETX mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 3:12,428,091...12,480,801
Ensembl chr 3:12,427,635...12,480,803
|
|
G |
Sfxn5 |
sideroflexin 5 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFXN5 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:117,750,213...117,869,826
Ensembl chr 4:117,752,806...117,869,794
|
|
G |
Sh3pxd2b |
SH3 and PX domains 2B |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SH3PXD2B mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170
|
|
G |
Sik1 |
salt-inducible kinase 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SIK1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
|
|
G |
Simc1 |
SUMO-interacting motifs containing 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SIMC1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:10,061,752...10,106,938
Ensembl chr17:10,061,757...10,106,910
|
|
G |
Sla2 |
Src-like-adaptor 2 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLA2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 3:145,367,070...145,383,586
Ensembl chr 3:145,368,598...145,382,480
|
|
G |
Slc12a1 |
solute carrier family 12 member 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC12A1 protein |
CTD |
PMID:16189294 |
|
NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
|
|
G |
Slc12a3 |
solute carrier family 12 member 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC12A3 protein |
CTD |
PMID:16189294 |
|
NCBI chr19:10,630,651...10,679,250
Ensembl chr19:10,631,393...10,669,091
|
|
G |
Slc13a2 |
solute carrier family 13 member 2 |
increases secretion |
EXP |
Mercuric Chloride results in increased secretion of SLC13A2 protein |
CTD |
PMID:20407758 |
|
NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127
|
|
G |
Slc15a1 |
solute carrier family 15 member 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SLC15A1 mRNA |
CTD |
PMID:31175882 |
|
NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
|
|
G |
Slc16a6 |
solute carrier family 16, member 6 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC16A6 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779
|
|
G |
Slc19a3 |
solute carrier family 19 member 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC19A3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
|
|
G |
Slc20a1 |
solute carrier family 20 member 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SLC20A1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
|
|
G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions decreases activity decreases expression |
ISO EXP |
[Mercuric Chloride results in decreased activity of SLC22A2 protein] which results in decreased uptake of Tetraethylammonium Mercuric Chloride results in decreased expression of SLC22A2 mRNA |
CTD |
PMID:17287197 PMID:28536007 |
|
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
|
|
G |
Slc22a25 |
solute carrier family 22, member 25 |
decreases expression increases secretion |
EXP |
Mercuric Chloride results in decreased expression of SLC22A9 mRNA; Mercuric Chloride results in decreased expression of SLC22A9 protein Mercuric Chloride results in increased secretion of SLC22A9 protein |
CTD |
PMID:20407758 |
|
NCBI chr 1:205,338,698...205,498,486
Ensembl chr 1:205,338,699...205,433,085
|
|
G |
Slc22a3 |
solute carrier family 22 member 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SLC22A3 mRNA |
CTD |
PMID:28536007 |
|
NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
|
|
G |
Slc22a5 |
solute carrier family 22 member 5 |
decreases expression multiple interactions decreases transport |
EXP |
Mercuric Chloride results in decreased expression of SLC22A5 mRNA Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased transport of SLC22A5 protein]; Cysteine inhibits the reaction [Mercuric Chloride results in decreased transport of SLC22A5 protein]; Dithioerythritol inhibits the reaction [Mercuric Chloride results in decreased transport of SLC22A5 protein] |
CTD |
PMID:16507785 PMID:22900493 |
|
NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
|
|
G |
Slc22a6 |
solute carrier family 22 member 6 |
decreases expression increases expression |
EXP ISO |
Mercuric Chloride results in decreased expression of SLC22A6 mRNA Mercuric Chloride results in increased expression of SLC22A6 protein |
CTD |
PMID:16507785 PMID:26788513 PMID:28536007 PMID:30031051 |
|
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
|
|
G |
Slc22a8 |
solute carrier family 22 member 8 |
multiple interactions decreases expression increases expression |
EXP ISO |
Mercuric Chloride results in decreased expression of and affects the localization of SLC22A8 protein Mercuric Chloride results in decreased expression of SLC22A8 mRNA Mercuric Chloride results in increased expression of SLC22A8 protein |
CTD |
PMID:19533102 PMID:26788513 PMID:27720909 PMID:30031051 |
|
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
|
|
G |
Slc24a3 |
solute carrier family 24 member 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC24A3 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 3:132,552,119...133,051,192
Ensembl chr 3:132,551,595...133,051,192
|
|
G |
Slc25a1 |
solute carrier family 25 member 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC25A1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781
|
|
G |
Slc25a20 |
solute carrier family 25 member 20 |
multiple interactions decreases activity |
ISO |
Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of SLC25A20 protein]; Dithioerythritol inhibits the reaction [Mercuric Chloride results in decreased activity of SLC25A20 protein]; Glutathione inhibits the reaction [Mercuric Chloride results in decreased activity of SLC25A20 protein] |
CTD |
PMID:25849418 |
|
NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
|
|
G |
Slc25a25 |
solute carrier family 25 member 25 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SLC25A25 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
|
|
G |
Slc25a33 |
solute carrier family 25 member 33 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SLC25A33 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:160,195,040...160,219,961
Ensembl chr 5:160,195,042...160,219,961
|
|
G |
Slc25a36 |
solute carrier family 25 member 36 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SLC25A36 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 8:97,659,848...97,693,735
Ensembl chr 8:97,662,127...97,693,703
|
|
G |
Slc28a1 |
solute carrier family 28 member 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC28A1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464
|
|
G |
Slc29a1 |
solute carrier family 29 member 1 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of SLC29A1 mRNA |
CTD |
PMID:31175882 |
|
NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
|
|
G |
Slc29a3 |
solute carrier family 29 member 3 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC29A3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr20:28,645,265...28,685,388
Ensembl chr20:28,647,391...28,685,388
|
|
G |
Slc2a2 |
solute carrier family 2 member 2 |
multiple interactions |
EXP |
Mercuric Chloride inhibits the reaction [Cytochalasin B binds to SLC2A2 protein]; Mercuric Chloride inhibits the reaction [SLC2A2 protein results in increased uptake of 3-O-Methylglucose] |
CTD |
PMID:10825458 |
|
NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
|
|
G |
Slc2a3 |
solute carrier family 2 member 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SLC2A3 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
|
|
G |
Slc2a4 |
solute carrier family 2 member 4 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SLC2A4 protein |
CTD |
PMID:12883084 |
|
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
|
|
G |
Slc30a1 |
solute carrier family 30 member 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SLC30A1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
|
|
G |
Slc30a5 |
solute carrier family 30 member 5 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC30A5 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 2:31,945,745...31,975,969
Ensembl chr 2:31,945,729...31,975,934
|
|
G |
Slc37a4 |
solute carrier family 37 member 4 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC37A4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
|
|
G |
Slc3a2 |
solute carrier family 3 member 2 |
multiple interactions |
ISO |
Mercaptoethanol promotes the reaction [Mercuric Chloride inhibits the reaction [SLC3A2 protein results in increased uptake of Amino Acids, Peptides, and Proteins]]; Mercuric Chloride inhibits the reaction [SLC3A2 protein results in increased uptake of Amino Acids, Peptides, and Proteins] |
CTD |
PMID:9761775 |
|
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
|
|
G |
Slc40a1 |
solute carrier family 40 member 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SLC40A1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
|
|
G |
Slc47a2 |
solute carrier family 47 member 2 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of SLC47A2 mRNA |
CTD |
PMID:27720909 |
|
NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
|
|
G |
Slc51b |
SLC51 subunit beta |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SLC51B mRNA |
CTD |
PMID:31175882 |
|
NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145
|
|
G |
Slc6a4 |
solute carrier family 6 member 4 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC6A4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
|
|
G |
Slc6a9 |
solute carrier family 6 member 9 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SLC6A9 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
|
|
G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of SLC7A11 mRNA |
CTD |
PMID:38568856 |
|
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
|
|
G |
Slc7a5 |
solute carrier family 7 member 5 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SLC7A5 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
|
|
G |
Slc7a7 |
solute carrier family 7 member 7 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC7A7 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr15:27,822,088...27,873,121
Ensembl chr15:27,822,091...27,865,648
|
|
G |
Slc7a9 |
solute carrier family 7 member 9 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLC7A9 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:88,109,517...88,132,653
Ensembl chr 1:88,110,644...88,132,641
|
|
G |
Slc9a3 |
solute carrier family 9 member A3 |
decreases expression multiple interactions |
EXP |
Mercuric Chloride results in decreased expression of SLC9A3 protein Mercuric Chloride results in decreased activity of and results in increased phosphorylation of SLC9A3 protein |
CTD |
PMID:16189294 PMID:33476711 |
|
NCBI chr 1:29,124,633...29,167,912
Ensembl chr 1:29,124,674...29,167,417
|
|
G |
Slco1a4 |
solute carrier organic anion transporter family, member 1a4 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SLCO1A2 mRNA |
CTD |
PMID:28536007 |
|
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
|
|
G |
Slco4c1 |
solute carrier organic anion transporter family, member 4C1 |
decreases expression |
ISO EXP |
Mercuric Chloride results in decreased expression of SLCO4C1 mRNA |
CTD |
PMID:27720909 PMID:28536007 |
|
NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715
|
|
G |
Smtnl2 |
smoothelin-like 2 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SMTNL2 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:57,008,322...57,029,505
Ensembl chr10:57,008,327...57,029,505
|
|
G |
Sncaip |
synuclein, alpha interacting protein |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SNCAIP mRNA |
CTD |
PMID:32599119 |
|
NCBI chr18:46,205,846...46,343,932
Ensembl chr18:46,207,152...46,343,929
|
|
G |
Sod1 |
superoxide dismutase 1 |
increases expression increases activity |
EXP |
Mercuric Chloride results in increased expression of SOD1 protein Mercuric Chloride results in increased activity of SOD1 protein |
CTD |
PMID:15977196 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
|
|
G |
Sod2 |
superoxide dismutase 2 |
increases activity multiple interactions increases expression decreases expression |
EXP ISO |
Mercuric Chloride results in increased activity of SOD2 protein Dexamethasone inhibits the reaction [Mercuric Chloride results in increased expression of SOD2 protein]; Mercuric Chloride results in decreased activity of and results in increased reduction of SOD2 protein; Mercuric Chloride results in increased expression of and results in increased activity of SOD2 protein Mercuric Chloride results in increased expression of SOD2 mRNA; Mercuric Chloride results in increased expression of SOD2 protein Berberine inhibits the reaction [Mercuric Chloride results in decreased expression of SOD2 mRNA] |
CTD |
PMID:9374288 PMID:12111001 PMID:15977196 PMID:21232032 PMID:23415682 PMID:24751971 PMID:33460233 More...
|
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
|
|
G |
Sod3 |
superoxide dismutase 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SOD3 protein |
CTD |
PMID:18599595 PMID:23415682 |
|
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
|
|
G |
Sp1 |
Sp1 transcription factor |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SP1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
|
|
G |
Spata6l |
spermatogenesis associated 6-like |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPATA6L mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:226,630,470...226,682,979
Ensembl chr 1:226,641,518...226,682,884
|
|
G |
Spn |
sialophorin |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
|
NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
|
|
G |
Spock1 |
sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SPOCK1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:6,741,504...7,221,685
Ensembl chr17:6,742,273...7,224,935
|
|
G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions increases expression |
ISO EXP |
[Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of SPP1 protein Mercuric Chloride results in increased expression of SPP1 mRNA; Mercuric Chloride results in increased expression of SPP1 protein [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA |
CTD |
PMID:11274264 PMID:21084432 PMID:26272509 PMID:27188386 |
|
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
|
|
G |
Spsb1 |
splA/ryanodine receptor domain and SOCS box containing 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SPSB1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468
|
|
G |
Sptbn1 |
spectrin, beta, non-erythrocytic 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SPTBN1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
|
|
G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
increases expression |
ISO |
Mercuric Chloride results in increased expression of SRC mRNA |
CTD |
PMID:37172713 |
|
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
|
|
G |
Srebf2 |
sterol regulatory element binding transcription factor 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SREBF2 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
|
|
G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SRXN1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
|
|
G |
Star |
steroidogenic acute regulatory protein |
decreases expression multiple interactions |
EXP |
Mercuric Chloride results in decreased expression of STAR mRNA alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of STAR mRNA] |
CTD |
PMID:32134168 |
|
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Glutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Glutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]; Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT1 protein]; Mercuric Chloride inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; Thioctic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT1 protein]] |
CTD |
PMID:16896058 PMID:19635391 |
|
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions increases phosphorylation increases expression |
ISO |
Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]; Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]; Glutathione inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]; Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]; Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]; Thioctic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF results in increased phosphorylation of STAT3 protein]] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Mercuric Chloride results in increased phosphorylation of STAT3 protein] Mercuric Chloride analog results in increased phosphorylation of STAT3 protein; Mercuric Chloride results in increased phosphorylation of STAT3 protein Mercuric Chloride results in increased expression of STAT3 mRNA |
CTD |
PMID:16896058 PMID:19635391 PMID:29981841 PMID:37172713 |
|
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
|
|
G |
Stat6 |
signal transducer and activator of transcription 6 |
increases phosphorylation |
EXP |
Mercuric Chloride results in increased phosphorylation of STAT6 protein |
CTD |
PMID:19604304 |
|
NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
|
|
G |
Stbd1 |
starch binding domain 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of STBD1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
|
|
G |
Stip1 |
stress-induced phosphoprotein 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of STIP1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476
|
|
G |
Stra6 |
signaling receptor and transporter of retinol STRA6 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of STRA6 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860
|
|
G |
Suox |
sulfite oxidase |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of SUOX mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
|
|
G |
Supt16h |
SPT16 homolog, facilitates chromatin remodeling subunit |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SUPT16H mRNA |
CTD |
PMID:27188386 |
|
NCBI chr15:24,867,697...24,904,818
Ensembl chr15:24,866,489...24,904,846
|
|
G |
Susd2 |
sushi domain containing 2 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of SUSD2 mRNA |
CTD |
PMID:38568856 |
|
NCBI chr20:13,017,516...13,024,820
Ensembl chr20:13,017,477...13,024,903
|
|
G |
Syk |
spleen associated tyrosine kinase |
multiple interactions |
ISO |
Mercuric Chloride promotes the reaction [CD22 protein results in increased phosphorylation of SYK protein] |
CTD |
PMID:17656488 |
|
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
|
|
G |
Syne4 |
spectrin repeat containing nuclear envelope family member 4 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of SYNE4 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr 1:85,569,409...85,573,775
Ensembl chr 1:85,569,545...85,573,760
|
|
G |
Syt8 |
synaptotagmin 8 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of SYT8 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:197,588,126...197,593,598
Ensembl chr 1:197,590,149...197,593,504
|
|
G |
Tac1 |
tachykinin, precursor 1 |
multiple interactions |
ISO |
Mercuric Chloride promotes the reaction [TAC1 protein results in increased secretion of IL6 protein] |
CTD |
PMID:20222982 |
|
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
|
|
G |
Tardbp |
TAR DNA binding protein |
increases expression |
EXP |
Mercuric Chloride results in increased expression of TARDBP mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
|
|
G |
Tars1 |
threonyl-tRNA synthetase 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of TARS1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717
|
|
G |
Tf |
transferrin |
increases expression |
EXP |
Mercuric Chloride results in increased expression of TF protein |
CTD |
PMID:21549428 |
|
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
|
|
G |
Tfrc |
transferrin receptor |
increases expression |
ISO |
Mercuric Chloride results in increased expression of TFRC protein |
CTD |
PMID:9693280 |
|
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
|
|
G |
Tgfa |
transforming growth factor alpha |
increases expression |
EXP |
Mercuric Chloride results in increased expression of TGFA mRNA; Mercuric Chloride results in increased expression of TGFA protein |
CTD |
PMID:10901180 |
|
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases expression decreases activity |
EXP ISO |
Tacrolimus inhibits the reaction [Mercuric Chloride results in increased expression of TGFB1 protein] Mercuric Chloride results in increased expression of TGFB1 mRNA; Mercuric Chloride results in increased expression of TGFB1 protein Mercuric Chloride results in decreased activity of TGFB1 protein |
CTD |
PMID:10469268 PMID:14620542 PMID:31652400 |
|
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
|
|
G |
Tgif1 |
TGFB-induced factor homeobox 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of TGIF1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
|
|
G |
Thbs1 |
thrombospondin 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of THBS1 mRNA; Mercuric Chloride results in increased expression of THBS1 protein |
CTD |
PMID:16005714 |
|
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
|
|
G |
Thbs4 |
thrombospondin 4 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of THBS4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
|
|
G |
Thy1 |
Thy-1 cell surface antigen |
multiple interactions |
ISO |
Mercuric Chloride promotes the reaction [THY1 protein binds to THY1 protein] |
CTD |
PMID:7698341 |
|
NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
|
|
G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of TIMP1 mRNA |
CTD |
PMID:11817102 |
|
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
|
|
G |
Timp4 |
TIMP metallopeptidase inhibitor 4 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of TIMP4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
|
|
G |
Tmem106b |
transmembrane protein 106B |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of TMEM106B mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
|
|
G |
Tmem86a |
transmembrane protein 86A |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of TMEM86A mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 1:97,595,910...97,600,260
Ensembl chr 1:97,595,842...97,600,260
|
|
G |
Tmtc3 |
transmembrane O-mannosyltransferase targeting cadherins 3 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of TMTC3 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions increases secretion decreases expression increases expression affects secretion affects expression |
ISO EXP |
Mercuric Chloride inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; Mercuric Chloride inhibits the reaction [TNF results in increased activity of [RELA protein binds to NFKB1 protein]]; Mercuric Chloride promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Mercuric Chloride results in increased secretion of TNF protein [lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of TNF protein; [Sodium Selenite co-treated with zinc chloride] affects the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of TNF protein]; Berberine inhibits the reaction [Mercuric Chloride results in increased expression of TNF protein]; Mercuric Chloride inhibits the reaction [TNF results in increased activity of [RELA protein binds to NFKB1 protein]]; Mycophenolic Acid inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; Mycophenolic Acid inhibits the reaction [Mercuric Chloride results in increased secretion of TNF protein]; Pentoxifylline inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; Selenium affects the reaction [Mercuric Chloride results in decreased expression of TNF protein]; Sodium Selenite affects the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of TNF protein]; Tretinoin inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; zinc chloride inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of TNF protein] Mercuric Chloride results in decreased expression of TNF mRNA Mercuric Chloride results in increased expression of TNF mRNA; Mercuric Chloride results in increased expression of TNF protein [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; Mercuric Chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA]; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; SB 203580 inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA] Mercuric Chloride affects the secretion of TNF protein; Mercuric Chloride analog affects the secretion of TNF protein Mercuric Chloride affects the expression of TNF mRNA |
CTD |
PMID:7589090 PMID:8560497 PMID:11912253 PMID:12175822 PMID:12426138 PMID:12849721 PMID:15050407 PMID:17250768 PMID:19203382 PMID:20049214 PMID:21984480 PMID:25237059 PMID:25600690 PMID:26089086 PMID:28453771 PMID:29981841 PMID:32134168 PMID:36416909 PMID:36646412 PMID:37172713 More...
|
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
|
G |
Tnfrsf12a |
TNF receptor superfamily member 12A |
increases expression |
EXP |
Mercuric Chloride results in increased expression of TNFRSF12A mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
|
|
G |
Tnfrsf4 |
TNF receptor superfamily member 4 |
increases expression multiple interactions |
EXP |
Mercuric Chloride results in increased expression of TNFRSF4 protein Mercuric Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Staurosporine promotes the reaction [Mercuric Chloride results in increased expression of TNFRSF4 protein] |
CTD |
PMID:9766631 |
|
NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
|
|
G |
Tp53 |
tumor protein p53 |
increases expression |
ISO |
Mercuric Chloride results in increased expression of TRP53 mRNA |
CTD |
PMID:23202902 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
|
|
G |
Tp53bp1 |
tumor protein p53 binding protein 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of TP53BP1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
|
|
G |
Tpsg1 |
tryptase gamma 1 |
multiple interactions |
ISO |
[NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TPSG1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:14,386,352...14,390,258
Ensembl chr10:14,386,352...14,390,258
|
|
G |
Trdmt1 |
tRNA aspartic acid methyltransferase 1 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of TRDMT1 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr17:76,601,966...76,646,104
Ensembl chr17:76,610,543...76,645,439
|
|
G |
Trib1 |
tribbles pseudokinase 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of TRIB1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
|
|
G |
Trim5 |
tripartite motif-containing 5 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of TRIM5 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:158,720,407...158,737,393
Ensembl chr 1:158,720,410...158,814,012
|
|
G |
Trpc4 |
transient receptor potential cation channel, subfamily C, member 4 |
increases activity multiple interactions |
ISO |
Mercuric Chloride results in increased activity of TRPC4 protein 2-aminoethoxydiphenyl borate inhibits the reaction [Mercuric Chloride results in increased activity of TRPC4 protein] |
CTD |
PMID:21984481 |
|
NCBI chr 2:138,307,676...138,476,856
Ensembl chr 2:138,308,084...138,476,768
|
|
G |
Trpc5 |
transient receptor potential cation channel, subfamily C, member 5 |
multiple interactions increases activity affects response to substance |
ISO |
2-aminoethoxydiphenyl borate inhibits the reaction [Mercuric Chloride results in increased activity of TRPC5 protein]; Dithiothreitol inhibits the reaction [Mercuric Chloride results in increased activity of TRPC5 protein] TRPC5 mRNA affects the susceptibility to Mercuric Chloride |
CTD |
PMID:21984481 |
|
NCBI chr X:107,946,163...108,230,991
Ensembl chr X:107,939,131...108,230,991
|
|
G |
Trpm2 |
transient receptor potential cation channel, subfamily M, member 2 |
multiple interactions |
ISO |
Mercuric Chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein] |
CTD |
PMID:22750002 |
|
NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
|
|
G |
Tsc22d3 |
TSC22 domain family, member 3 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of TSC22D3 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr X:104,217,898...104,277,886
Ensembl chr X:104,217,925...104,276,861
|
|
G |
Tulp4 |
TUB like protein 4 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of TULP4 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 1:46,682,416...46,813,167
Ensembl chr 1:46,682,863...46,809,688
|
|
G |
Txn1 |
thioredoxin 1 |
multiple interactions decreases expression increases oxidation |
ISO |
Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of TXN protein]; Mercuric Chloride inhibits the reaction [Lipopolysaccharides results in decreased expression of TXN protein]; Mercuric Chloride results in decreased activity of and affects the metabolism of TXN protein; sodium selenide inhibits the reaction [Mercuric Chloride results in decreased expression of TXN protein] Mercuric Chloride results in increased oxidation of TXN protein |
CTD |
PMID:16337887 PMID:17959236 PMID:18321861 |
|
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
|
|
G |
Txn2 |
thioredoxin 2 |
increases oxidation |
ISO |
Mercuric Chloride results in increased oxidation of TXN2 protein |
CTD |
PMID:16337887 |
|
NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
|
|
G |
Txnrd1 |
thioredoxin reductase 1 |
multiple interactions decreases activity increases expression |
ISO EXP |
Mercuric Chloride promotes the reaction [Sodium Selenite results in increased expression of TXNRD1 mRNA]; Sodium Selenite inhibits the reaction [Mercuric Chloride results in decreased activity of TXNRD1 protein]; Sodium Selenite promotes the reaction [Mercuric Chloride results in increased expression of TXNRD1 mRNA]; Sodium Selenite promotes the reaction [Mercuric Chloride results in increased expression of TXNRD1 protein] [Sodium Selenite co-treated with NADP] inhibits the reaction [Mercuric Chloride results in decreased activity of TXNRD1 protein]; Dimercaprol inhibits the reaction [Mercuric Chloride results in decreased activity of TXNRD1 protein]; dimethyl mercaptosuccinate inhibits the reaction [Mercuric Chloride results in decreased activity of TXNRD1 protein]; Thioctic Acid inhibits the reaction [Mercuric Chloride results in decreased activity of TXNRD1 protein]; Unithiol inhibits the reaction [Mercuric Chloride results in decreased activity of TXNRD1 protein] Mercuric Chloride results in increased expression of TXNRD1 mRNA; Mercuric Chloride results in increased expression of TXNRD1 protein |
CTD |
PMID:16507785 PMID:17959236 PMID:18321861 PMID:20810785 PMID:24816296 |
|
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
|
|
G |
Txnrd2 |
thioredoxin reductase 2 |
decreases activity |
EXP ISO |
Mercuric Chloride results in decreased activity of TXNRD2 protein |
CTD |
PMID:17157198 PMID:24816296 |
|
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
|
|
G |
U2surp |
U2 snRNP-associated SURP domain containing |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of U2SURP mRNA |
CTD |
PMID:27188386 |
|
NCBI chr 8:96,018,932...96,075,795
Ensembl chr 8:96,022,957...96,075,691
|
|
G |
Uba6 |
ubiquitin-like modifier activating enzyme 6 |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of UBA6 mRNA |
CTD |
PMID:27188386 |
|
NCBI chr14:21,884,039...21,947,857
Ensembl chr14:21,884,039...21,947,857
|
|
G |
Ube2b |
ubiquitin-conjugating enzyme E2B |
increases expression |
EXP |
Mercuric Chloride results in increased expression of UBE2B mRNA |
CTD |
PMID:16507785 |
|
NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665
|
|
G |
Ube2z |
ubiquitin-conjugating enzyme E2Z |
decreases expression |
ISO |
Mercuric Chloride results in decreased expression of UBE2Z mRNA |
CTD |
PMID:27188386 |
|
NCBI chr10:80,997,816...81,016,936
Ensembl chr10:80,997,817...81,016,936
|
|
G |
Ubqln1 |
ubiquilin 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of UBQLN1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090
|
|
G |
Ubr4 |
ubiquitin protein ligase E3 component n-recognin 4 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of UBR4 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784
|
|
G |
Ucp1 |
uncoupling protein 1 |
decreases expression |
EXP |
Mercuric Chloride results in decreased expression of UCP1 mRNA |
CTD |
PMID:32599119 |
|
NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
|
|
G |
Ugdh |
UDP-glucose 6-dehydrogenase |
increases expression |
EXP |
Mercuric Chloride results in increased expression of UGDH mRNA |
CTD |
PMID:16507785 |
|
NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
|
|
G |
Uggt1 |
UDP-glucose glycoprotein glucosyltransferase 1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of UGGT1 mRNA |
CTD |
PMID:16507785 |
|
NCBI chr 9:38,355,229...38,468,473
Ensembl chr 9:38,359,089...38,468,467
|
|