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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Mequitazine
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Accession:CHEBI:31821 term browser browse the term
Definition:A phenothiazine that has formula C20H22N2S.
Synonyms:related_synonym: Formula=C20H22N2S;   InChI=1S/C20H22N2S/c1-3-7-19-17(5-1)22(18-6-2-4-8-20(18)23-19)14-16-13-21-11-9-15(16)10-12-21/h1-8,15-16H,9-14H2;   InChIKey=HOKDBMAJZXIPGC-UHFFFAOYSA-N;   SMILES=C(C1CN2CCC1CC2)N1c2ccccc2Sc2ccccc12;   metaplexan;   nipolazin
 xref: CAS:29216-28-2;   Drug_Central:1707;   HMDB:HMDB0015204;   KEGG:C12755;   KEGG:D01324
 xref_mesh: MESH:C006069


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Mequitazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases hydroxylation
multiple interactions
ISO CYP2D6 protein results in increased hydroxylation of mequitazine
Nicardipine inhibits the reaction [CYP2D6 protein results in increased hydroxylation of mequitazine]
CTD PMID:15863898 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19767
    chemical entity 19767
      molecular entity 19766
        polyatomic entity 19685
          molecule 19526
            cyclic compound 19359
              polycyclic compound 18613
                heteropolycyclic compound 17978
                  heterotricyclic compound 14605
                    organic heterotricyclic compound 14605
                      phenothiazines 352
                        Mequitazine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19767
    subatomic particle 19766
      composite particle 19766
        hadron 19766
          baryon 19766
            nucleon 19766
              atomic nucleus 19766
                atom 19766
                  main group element atom 19657
                    p-block element atom 19657
                      carbon group element atom 19573
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19496
                              organic cyclic compound 19322
                                organic heterocyclic compound 18510
                                  organic heteropolycyclic compound 17978
                                    organic heterotricyclic compound 14605
                                      phenothiazines 352
                                        Mequitazine 1
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