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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Mequitazine
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Accession:CHEBI:31821 term browser browse the term
Definition:A phenothiazine that has formula C20H22N2S.
Synonyms:related_synonym: Formula=C20H22N2S;   InChI=1S/C20H22N2S/c1-3-7-19-17(5-1)22(18-6-2-4-8-20(18)23-19)14-16-13-21-11-9-15(16)10-12-21/h1-8,15-16H,9-14H2;   InChIKey=HOKDBMAJZXIPGC-UHFFFAOYSA-N;   SMILES=C(C1CN2CCC1CC2)N1c2ccccc2Sc2ccccc12;   metaplexan;   nipolazin
 xref: CAS:29216-28-2;   Drug_Central:1707;   HMDB:HMDB0015204;   KEGG:C12755;   KEGG:D01324
 xref_mesh: MESH:C006069


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Mequitazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases hydroxylation
multiple interactions
ISO CYP2D6 protein results in increased hydroxylation of mequitazine
Nicardipine inhibits the reaction [CYP2D6 protein results in increased hydroxylation of mequitazine]
CTD PMID:15863898 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    chemical entity 19771
      molecular entity 19770
        polyatomic entity 19688
          molecule 19527
            cyclic compound 19358
              polycyclic compound 18613
                heteropolycyclic compound 17977
                  heterotricyclic compound 14606
                    organic heterotricyclic compound 14606
                      phenothiazines 353
                        Mequitazine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      carbon group element atom 19574
                        carbon atom 19564
                          organic molecular entity 19564
                            organic molecule 19497
                              organic cyclic compound 19321
                                organic heterocyclic compound 18512
                                  organic heteropolycyclic compound 17977
                                    organic heterotricyclic compound 14606
                                      phenothiazines 353
                                        Mequitazine 1
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