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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Medazepam
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Accession:CHEBI:31807 term browser browse the term
Synonyms:related_synonym: Formula=C16H15ClN2;   InChI=1S/C16H15ClN2/c1-19-10-9-18-16(12-5-3-2-4-6-12)14-11-13(17)7-8-15(14)19/h2-8,11H,9-10H2,1H3;   InChIKey=YLCXGBZIZBEVPZ-UHFFFAOYSA-N;   SMILES=C1(=CC2=C(C=C1)N(CCN=C2C=3C=CC=CC3)C)Cl;   medazepam HCl;   medazepam hydrochloride;   mezapam
 xref: CAS:2898-12-6;   Drug_Central:1654;   KEGG:D01292
 xref_mesh: MESH:D008472


show annotations for term's descendants           Sort by:
Medazepam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C1 aldo-keto reductase family 1 member C1 decreases activity EXP Medazepam results in decreased activity of AKR1C1 protein CTD PMID:11995921 PMID:12604236 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283 		JBrowse link
G AKR1C2 aldo-keto reductase family 1 member C2 decreases activity EXP Medazepam results in decreased activity of AKR1C2 protein CTD PMID:11995921 PMID:12604236 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 decreases activity EXP Medazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 PMID:12604236 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686 		JBrowse link
G AKR1C4 aldo-keto reductase family 1 member C4 decreases activity EXP Medazepam results in decreased activity of AKR1C4 protein CTD PMID:12604236 NCBI chr10:5,196,837...5,218,949
Ensembl chr10:5,195,462...5,218,949 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases expression EXP Medazepam results in increased expression of CYP3A4 mRNA CTD PMID:20080160 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions
increases activity		 EXP Medazepam binds to and results in increased activity of NR1I2 protein
Medazepam results in increased activity of NR1I2 protein		 CTD PMID:20024649 PMID:20080160 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    chemical entity 26024
      atom 26009
        nonmetal atom 25498
          carbon atom 25403
            organic molecular entity 25392
              Medazepam 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      carbon group element atom 25434
                        carbon atom 25403
                          organic molecular entity 25392
                            Medazepam 6
paths to the root