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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Medazepam
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Accession:CHEBI:31807 term browser browse the term
Synonyms:related_synonym: Formula=C16H15ClN2;   InChI=1S/C16H15ClN2/c1-19-10-9-18-16(12-5-3-2-4-6-12)14-11-13(17)7-8-15(14)19/h2-8,11H,9-10H2,1H3;   InChIKey=YLCXGBZIZBEVPZ-UHFFFAOYSA-N;   SMILES=C1(=CC2=C(C=C1)N(CCN=C2C=3C=CC=CC3)C)Cl;   medazepam HCl;   medazepam hydrochloride;   mezapam
 xref: CAS:2898-12-6;   Drug_Central:1654;   KEGG:D01292
 xref_mesh: MESH:D008472


show annotations for term's descendants           Sort by:
 
Medazepam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO Medazepam results in decreased activity of AKR1C4 protein CTD PMID:12604236 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Medazepam results in decreased activity of AKR1C2 protein CTD PMID:11995921, PMID:12604236 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Medazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921, PMID:12604236 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO Medazepam binds to and results in increased activity of NR1I2 protein
Medazepam results in increased activity of NR1I2 protein
CTD PMID:20024649, PMID:20080160 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Medazepam 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Medazepam 4
paths to the root

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