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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Maxacalcitol
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Accession:CHEBI:31801 term browser browse the term
Synonyms:related_synonym: 22-oxacalcitriol;   Formula=C26H42O4;   InChI=1S/C26H42O4/c1-17-20(15-21(27)16-24(17)28)9-8-19-7-6-12-26(5)22(10-11-23(19)26)18(2)30-14-13-25(3,4)29/h8-9,18,21-24,27-29H,1,6-7,10-16H2,2-5H3/b19-8+,20-9-/t18-,21+,22+,23-,24-,26+/m0/s1;   InChIKey=DTXXSJZBSTYZKE-ZDQKKZTESA-N;   SMILES=C[C@@]12[C@](/C(=C/C=C/3\\C(=C)[C@@H](O)C[C@@H](C3)O)/CCC1)(CC[C@@]2([C@@H](OCCC(C)(C)O)C)[H])[H];   oxarol
 xref: CAS:103909-75-7;   Drug_Central:1638;   KEGG:D01098
 xref_mesh: MESH:C051883


show annotations for term's descendants           Sort by:
Maxacalcitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant decreases expression ISO maxacalcitol results in decreased expression of ACP5; maxacalcitol results in decreased expression of ACP5 protein CTD PMID:8840326 PMID:11576942 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO maxacalcitol results in increased expression of CDKN1A protein CTD PMID:16039115 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO maxacalcitol results in increased expression of CDKN1B protein CTD PMID:16039115 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO maxacalcitol results in increased expression of CYP24A1 mRNA CTD PMID:7530193 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Pth parathyroid hormone decreases expression
decreases secretion		 ISO
EXP		 maxacalcitol results in decreased expression of PTH protein
maxacalcitol results in decreased expression of PTH mRNA
maxacalcitol results in decreased secretion of PTH protein		 CTD PMID:8455354 PMID:8840326 PMID:11576942 PMID:16189633 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO maxacalcitol results in decreased phosphorylation of RB1 protein CTD PMID:16039115 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Tslp thymic stromal lymphopoietin increases expression ISO Oxarol increases expression of Tslp mRNA in ear skin RGD PMID:32060507 RGD:38549590 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Vdr vitamin D receptor multiple interactions ISO maxacalcitol affects the reaction [Calcitriol binds to VDR protein] CTD PMID:7530193 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    chemical entity 19816
      atom 19816
        nonmetal atom 19749
          carbon atom 19698
            organic molecular entity 19698
              Maxacalcitol 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            Maxacalcitol 8
paths to the root