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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Maxacalcitol
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Accession:CHEBI:31801 term browser browse the term
Synonyms:related_synonym: 22-oxacalcitriol;   Formula=C26H42O4;   InChI=1S/C26H42O4/c1-17-20(15-21(27)16-24(17)28)9-8-19-7-6-12-26(5)22(10-11-23(19)26)18(2)30-14-13-25(3,4)29/h8-9,18,21-24,27-29H,1,6-7,10-16H2,2-5H3/b19-8+,20-9-/t18-,21+,22+,23-,24-,26+/m0/s1;   InChIKey=DTXXSJZBSTYZKE-ZDQKKZTESA-N;   SMILES=C[C@@]12[C@](/C(=C/C=C/3\\C(=C)[C@@H](O)C[C@@H](C3)O)/CCC1)(CC[C@@]2([C@@H](OCCC(C)(C)O)C)[H])[H];   oxarol
 xref: CAS:103909-75-7;   Drug_Central:1638;   KEGG:D01098
 xref_mesh: MESH:C051883


show annotations for term's descendants           Sort by:
 
Maxacalcitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant decreases expression ISO maxacalcitol results in decreased expression of ACP5; maxacalcitol results in decreased expression of ACP5 protein CTD PMID:8840326, PMID:11576942 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO maxacalcitol results in increased expression of CDKN1A protein CTD PMID:16039115 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO maxacalcitol results in increased expression of CDKN1B protein CTD PMID:16039115 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO maxacalcitol results in increased expression of CYP24A1 mRNA CTD PMID:7530193 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Pth parathyroid hormone decreases expression
decreases secretion
ISO
EXP
maxacalcitol results in decreased expression of PTH protein
maxacalcitol results in decreased expression of PTH mRNA
maxacalcitol results in decreased secretion of PTH protein
CTD PMID:8455354, PMID:8840326, PMID:11576942, PMID:16189633 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO maxacalcitol results in decreased phosphorylation of RB1 protein CTD PMID:16039115 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression ISO Oxarol increases expression of Tslp mRNA in ear skin RGD PMID:32060507 RGD:38549590 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO maxacalcitol affects the reaction [Calcitriol binds to VDR protein] CTD PMID:7530193 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Maxacalcitol 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Maxacalcitol 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.