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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:loteprednol etabonate
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Accession:CHEBI:31784 term browser browse the term
Definition:An etabonate ester that has formula C24H31ClO7.
Synonyms:exact_synonym: chloromethyl 17alpha-[(ethoxycarbonyl)oxy]-11beta-hydroxy-3-oxoandrosta-1,4-diene-17beta-carboxylate
 related_synonym: Formula=C24H31ClO7;   InChI=1S/C24H31ClO7/c1-4-30-21(29)32-24(20(28)31-13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)19(16)18(27)12-23(17,24)3/h7,9,11,16-19,27H,4-6,8,10,12-13H2,1-3H3/t16-,17-,18-,19+,22-,23-,24-/m0/s1;   InChIKey=DMKSVUSAATWOCU-HROMYWEYSA-N;   SMILES=[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(OC(=O)OCC)C(=O)OCCl
 xref: Beilstein:5461012;   CAS:82034-46-6;   DrugBank:DB00873;   Drug_Central:1611;   KEGG:D01689
 xref_mesh: MESH:C063378


show annotations for term's descendants           Sort by:
loteprednol etabonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Loteprednol Etabonate binds to and results in decreased activity of AR protein; Loteprednol Etabonate binds to and results in increased activity of AR protein CTD PMID:25752796 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO Loteprednol Etabonate binds to and results in increased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19825
      application 19667
        anti-inflammatory agent 16629
          anti-inflammatory drug 14974
            loteprednol etabonate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19797
                    p-block element atom 19797
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            heteroorganic entity 19492
                              organochalcogen compound 19254
                                organooxygen compound 19170
                                  carbonyl compound 18893
                                    ketone 17191
                                      oxo steroid 10545
                                        3-oxo steroid 9934
                                          3-oxo-Delta(1) steroid 5225
                                            3-oxo-Delta(1),Delta(4)-steroid 5225
                                              loteprednol 2
                                                loteprednol etabonate 2
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