Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lentinan
go back to main search page
Accession:CHEBI:31770 term browser browse the term
Definition:A 1,3 beta-glucan polysaccharide with beta-1,6 branching isolated from the edible mushroom Lentinula edodes. It has a molecular weight of around 500,000 Da; the exact composition is unknown.
Synonyms:related_synonym: Formula=(C42H70O35)n
 xref: CAS:37339-90-5;   DrugBank:DB13480;   GlyTouCan:G09583ED;   KEGG:C13156;   KEGG:D01695
 xref_mesh: MESH:D007912
 xref: Wikipedia:Lentinan


show annotations for term's descendants           Sort by:
 
lentinan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO Lentinan results in decreased expression of CYP1A1 CTD PMID:15630237 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression ISO Lentinan results in decreased expression of CYP1A2 CTD PMID:15630237 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Lentinan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:22102286 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Lentinan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:22102286 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Lentinan inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Lentinan inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:22102286 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity
multiple interactions
ISO Lentinan results in increased activity of RELA
Lentinan promotes the reaction [Lipopolysaccharides results in increased localization of RELA protein]
CTD PMID:15630237 PMID:22102286 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO Lentinan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Lentinan inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
Lentinan results in increased expression of TNF
CTD PMID:15630237 PMID:22102286 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      biological role 19825
        immunomodulator 13755
          lentinan 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      p-block molecular entity 19763
                        carbon group molecular entity 19668
                          organic molecular entity 19657
                            heteroorganic entity 19248
                              organochalcogen compound 18956
                                organooxygen compound 18879
                                  carbohydrates and carbohydrate derivatives 12268
                                    carbohydrate 12268
                                      polysaccharide 3060
                                        homopolysaccharide 1379
                                          glucan 1360
                                            lentinan 7
paths to the root