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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:iomeprol
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Accession:CHEBI:31710 term browser browse the term
Definition:A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a glycoloyl(methyl)amino group at the 5-position.
Synonyms:exact_synonym: N,N'-bis(2,3-dihydroxypropyl)-5-[glycoloyl(methyl)amino]-2,4,6-triiodoisophthalamide
 related_synonym: Formula=C17H22I3N3O8;   InChI=1S/C17H22I3N3O8/c1-23(9(29)6-26)15-13(19)10(16(30)21-2-7(27)4-24)12(18)11(14(15)20)17(31)22-3-8(28)5-25/h7-8,24-28H,2-6H2,1H3,(H,21,30)(H,22,31);   InChIKey=NJKDOADNQSYQEV-UHFFFAOYSA-N;   N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(N-methylglycolamido)isophthalamide;   SMILES=CN(C(=O)CO)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I;   iomeprolum
 xref: Beilstein:8177227;   CAS:78649-41-9;   Drug_Central:1463;   KEGG:D01719
 xref_mesh: MESH:C057937
 xref: PMID:15206581;   Reaxys:8177227;   Wikipedia:Iomeprol



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iomeprol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP [Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein] CTD PMID:26474837 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP [Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein] CTD PMID:26474837 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO iomeprol results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO iomeprol results in increased phosphorylation of MAPK9 protein CTD PMID:21036957 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase affects expression ISO iomeprol affects the expression of PIM1 protein CTD PMID:21036957 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation ISO iomeprol results in increased phosphorylation of RELA protein CTD PMID:21036957 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects expression ISO iomeprol affects the expression of STAT3 protein modified form CTD PMID:21036957 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        xenobiotic 18699
          iomeprol 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      carboxylic acid 18597
                                        carboacyl group 17730
                                          univalent carboacyl group 17710
                                            carbamoyl group 17550
                                              carboxamide 17570
                                                dicarboxylic acid amide 3148
                                                  dicarboxylic acid diamide 2695
                                                    benzenedicarboxamide 61
                                                      iomeprol 7
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