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ONTOLOGY REPORT - ANNOTATIONS


Term:indolin-2-one
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Accession:CHEBI:31697 term browser browse the term
Definition:An indolinone carrying an oxo group at position 2.
Synonyms:related_synonym: 1,3-dihydro-(2H)-indol-2-One;   1,3-dihydroindol-2-one;   2-indolinone;   2-oxindole;   Formula=C8H7NO;   InChI=1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10);   InChIKey=JYGFTBXVXVMTGB-UHFFFAOYSA-N;   SMILES=O=C1Cc2ccccc2N1;   oxindole
 xref: Beilstein:114692 "Beilstein";   CAS:59-48-3 "ChemIDplus";   CAS:59-48-3 "NIST Chemistry WebBook";   Gmelin:637057 "Gmelin";   KEGG:C12312
 xref_mesh: MESH:C022960
 xref: PMID:24433962 "Europe PMC";   PMID:24500796 "Europe PMC";   Reaxys:114692 "Reaxys"


show annotations for term's descendants       view all columns           Sort by:
 
indolin-2-one term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    chemical entity 19660
      atom 19658
        nonmetal atom 19525
          nitrogen atom 18315
            nitrogen molecular entity 18315
              amide 16928
                cyclic amide 2855
                  lactam 2855
                    gamma-lactam 346
                      indolin-2-one 5
                        3-hydroxy-3-(thiazol-2-yl)indolin-2-one 0
                        oxindolyl group + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic group 18340
                              organic divalent group 18330
                                organodiyl group 18330
                                  carbonyl group 18217
                                    carbonyl compound 18217
                                      carboxylic acid 17921
                                        carboacyl group 16944
                                          univalent carboacyl group 16944
                                            carbamoyl group 16623
                                              carboxamide 16623
                                                lactam 2855
                                                  gamma-lactam 346
                                                    indolin-2-one 5
                                                      3-hydroxy-3-(thiazol-2-yl)indolin-2-one 0
                                                      oxindolyl group + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.